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Fusion gene ID: 29224 |
FusionGeneSummary for PSME3_TM9SF2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PSME3_TM9SF2 | Fusion gene ID: 29224 | Hgene | Tgene | Gene symbol | PSME3 | TM9SF2 | Gene ID | 10197 | 9375 |
| Gene name | proteasome activator subunit 3 | transmembrane 9 superfamily member 2 | |
| Synonyms | HEL-S-283|Ki|PA28-gamma|PA28G|PA28gamma|REG-GAMMA | P76 | |
| Cytomap | 17q21.31 | 13q32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | proteasome activator complex subunit 311S regulator complex gamma subunit11S regulator complex subunit gammaKi antigenKi nuclear autoantigenPA28 gamma variant 5REG gamma-3activator of multicatalytic protease subunit 3epididymis secretory protein L | transmembrane 9 superfamily member 276 kDa membrane proteindinucleotide oxidase disulfide thiol exchanger 3 superfamily member 2transmembrane protein 9 superfamily member 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P61289 | Q99805 | |
| Ensembl transtripts involved in fusion gene | ENST00000545225, ENST00000590720, ENST00000541124, ENST00000592578, ENST00000441946, ENST00000293362, ENST00000592169, | ENST00000376387, ENST00000463709, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 2 X 2 X 2=8 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/60*10)=0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: PSME3 [Title/Abstract] AND TM9SF2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PSME3 | GO:0061136 | regulation of proteasomal protein catabolic process | 18309296 |
| Hgene | PSME3 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway | 18309296 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-V1-A9ZR-01A | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000545225 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 5CDS-intron | ENST00000545225 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| In-frame | ENST00000590720 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 5CDS-intron | ENST00000590720 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 3UTR-3CDS | ENST00000541124 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 3UTR-intron | ENST00000541124 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| intron-3CDS | ENST00000592578 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| intron-intron | ENST00000592578 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| In-frame | ENST00000441946 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 5CDS-intron | ENST00000441946 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| In-frame | ENST00000293362 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 5CDS-intron | ENST00000293362 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| In-frame | ENST00000592169 | ENST00000376387 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
| 5CDS-intron | ENST00000592169 | ENST00000463709 | PSME3 | chr17 | 40991397 | + | TM9SF2 | chr13 | 100214945 | + |
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FusionProtFeatures for PSME3_TM9SF2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PSME3 | TM9SF2 |
| Subunit of the 11S REG-gamma (also called PA28-gamma)proteasome regulator, a doughnut-shaped homoheptamer whichassociates with the proteasome. 11S REG-gamma activates thetrypsin-like catalytic subunit of the proteasome but inhibits thechymotrypsin-like and postglutamyl-preferring (PGPH) subunits.Facilitates the MDM2-p53/TP53 interaction which promotesubiquitination- and MDM2-dependent proteasomal degradation ofp53/TP53, limiting its accumulation and resulting in inhibitedapoptosis after DNA damage. May also be involved in cell cycleregulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition(PubMed:25361978). {ECO:0000269|PubMed:10835274,ECO:0000269|PubMed:11185562, ECO:0000269|PubMed:11432824,ECO:0000269|PubMed:15111123, ECO:0000269|PubMed:18309296,ECO:0000269|PubMed:25361978, ECO:0000269|PubMed:9325261}. | In the intracellular compartments, may function as achannel or small molecule transporter. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 653_663 | 641 | 664 | Topological domain | Cytoplasmic |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 29_300 | 641 | 664 | Topological domain | Lumenal |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 322_374 | 641 | 664 | Topological domain | Cytoplasmic |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 396_398 | 641 | 664 | Topological domain | Lumenal |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 420_437 | 641 | 664 | Topological domain | Cytoplasmic |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 459_466 | 641 | 664 | Topological domain | Lumenal |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 488_522 | 641 | 664 | Topological domain | Cytoplasmic |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 544_554 | 641 | 664 | Topological domain | Lumenal |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 576_591 | 641 | 664 | Topological domain | Cytoplasmic |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 613_631 | 641 | 664 | Topological domain | Lumenal |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 301_321 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 375_395 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 399_419 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 438_458 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 467_487 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 523_543 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 555_575 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 592_612 | 641 | 664 | Transmembrane | Helical |
| Tgene | TM9SF2 | chr17:40991397 | chr13:100214945 | ENST00000376387 | + | 15 | 17 | 632_652 | 641 | 664 | Transmembrane | Helical |
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FusionGeneSequence for PSME3_TM9SF2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PSME3_ENST00000545225_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_189aa MNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGN NFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYEQLASLHAFGLLP >In-frame_PSME3_ENST00000590720_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_250aa MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLD ECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQIS >In-frame_PSME3_ENST00000441946_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_261aa MEKWILKKIKYLQSGGLSASYYSYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGL DGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVE >In-frame_PSME3_ENST00000293362_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_263aa MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLD ECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRT >In-frame_PSME3_ENST00000592169_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_194aa MASLLKVDQEVKLKVDSFRERITSEPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPR IEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYEQLASLHA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PSME3_ENST00000545225_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_569nt ATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGATGAG TGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAGAAA GTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGGAAAC AACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTCTAGA TATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGATGAG AAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCTTTTGGTTTGTTACCA >In-frame_PSME3_ENST00000590720_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_752nt ATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGCTCAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGGCAGAAGACTTGGTG GCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATCTTAAACATCCATGACCTAACTCAGATCCACTCT GACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGAT GAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAG AAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGGA AACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTCT AGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGAT GAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCTTTTGGTTTGTTA >In-frame_PSME3_ENST00000441946_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_785nt ATGGAAAAATGGATCCTCAAAAAAATAAAGTATTTGCAGTCTGGGGGCCTCTCAGCTTCTTATTACAGTTACAAGGTTGATTCTTTCAGG GAGCGGATCACAAGTGAGGCAGAAGACTTGGTGGCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATC TTAAACATCCATGACCTAACTCAGATCCACTCTGACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTG GATGGTCCCACTTATAAGAAGCGAAGGTTGGATGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTG AAAAGCAACCAGCAGCTGGTGGACATTATTGAGAAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGG GTACAGCTCCTGATTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAG AGTGAAGCTGCATCTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTG GAGGACTATCGCCGCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAA >In-frame_PSME3_ENST00000293362_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_791nt ATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGCTCAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGGCAGAAGACTTGGTG GCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATCTTAAACATCCATGACCTAACTCAGATCCACTCT GACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGAT GAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAG AAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGCCTTCAGGCAAAGGTCCTCATATATGTTTTGACCTCCAGGTCAAA ATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACT GTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCC CATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAA >In-frame_PSME3_ENST00000592169_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_584nt ATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGCTCAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGCCCACTTATAAGAAG CGAAGGTTGGATGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTG GACATTATTGAGAAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGG ATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTG GACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTG ACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PSME3_ENST00000545225_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_2656nt AAGTGTAGGAGCCAAGGCCGCAGAGAATGGGGAGGCTCCGCTATTCTCTAAATTCAGGGGGCGGCGGGCGCGGTGGCTCACGCCTGTAAT CTCAGCACTTGGGGAGGCCGAGGAGGGCGGATCACGTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACACAGTGAAACCCCGTCTCTAC TAAAAATACAAAAACTAGCCGGGCGTGGTGGGGCACGCCTATAATCCCAGCTTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCG CTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCGGGCCACTGCACTCCAGCCTGGGCGACAGGGCAAGGCTCCATCTCAGAACA ACAACAGCAACAACAAAAGGCCGGGCATGGTGGCTCACGCTTGTAATTCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACAAGGCTGG AGTGAAGCGGAACAAACAAACATGGCTCACTGCAGATTTGACTTCCTGGCTCAAGCAATCCTCTTGCTTCAACCTCCAGTGTAGCAGGGA CCACAGCATGAAAGCCCCTTTAGGGGAGGTGACTGGAATCATCCCCAAAGAATTCTCACCTAGTCCTGGTGTGGCTGCTTCATAGTCCTG CGTTTCTTCCTGCTTGGCTGTCCCTAACATCTCAGAAACGCATAGAGAAGTAACGGGCTTCTAGAGAGGTTGATTCTTTCAGGGAGCGGA TCACAAGTGAGGCAGAAGACTTGGTGGCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATCTTAAACA TCCATGACCTAACTCAGATCCACTCTGACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTC CCACTTATAAGAAGCGAAGGTTGGATGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCA ACCAGCAGCTGGTGGACATTATTGAGAAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGGGTACAGC TCCTGATTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAG CTGCATCTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACT ATCGCCGCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGG CTTCTTTGCATGCTTTTGGTTTGTTACCAAAATATACAGTGTGGTGAAGGTTGACTGAAGAAGTCCAGTGTGTCCAGTTAAAACAGAAAT AAATTAAACTCTTCATCAACAAAGACCTGTTTTTGTGACTGCCTTGAGTTTTATCAGAATTATTGGCCTAGTAATCCTTCAGAAACACCG TAATTCTAAATAAACCTCTTCCCATACACCTTTCCCCCATAAGATGTGTCTTCAACACTATAAAGCATTTGTATTGTGATTTGATTAAGT ATATATTTGGTTGTTCTCAATGAAGAGCAAATTTAAATATTATGTGCATTTGTAAATACAGTAGCTATAAAATTTTCCATACTTCTAATG GCAGAATAGAGGAGGCCATATTAAATAATACTGATGAAAGGCAGGACACTGCATTGTAAATAGGATTTTCTAGGCTCGGTAGGCAGAAAG AATTATTTTTCTTTGAAGGAAATAACTTTTTATCATGGTAATTTTGAAGGATGATTCCTATGATGTGTTCACCAGGGGAATGTGGCTTTT AAAGAAAATCTTCTATTGGTTGTAACTGTTCATATCTTCTTACTTTTCTGTGTTGACTTCATTATTCCCATGGTATTGGCCTTTTAAACT ATGTGCCTCTGAGTCTTTCAATTTATAAATTTGTTATCTTAATAAATATTATAAAAATGTCTTCATTGCATCATTACCTATTATATATTC AAGGAGGTTCTGTAAATACAGATCTATTTACCAAGGTGTTTTGAAATGATTTATACTATTTTATCAGATTTTACTGGATTTTGTTAATGT AACACTTTCTGAGTTTTGATCTGAATGGAATTTCACTGTGTAAGGCATTGTCTAAAATGTTCACTGTGAGGCAGTAGAGGAGGTTGAAGT CATGCATATCTAGACAGATGAATTATCTGCAAGTACTTAAGGTGGAGCCTTACTACATTGTCATTAAGGAGTTTCTATTTTTGACTTGTT TTTCAAAATACAGTGTTTTAAGTCAGGTTTTATTACCTGGACATTAGCAATCACTAGCAAGTCTTCATCTTTATGATTTCATTGTTTTAA TTTAGATTTCACAAACAGTTTTACTTCTAAGAGTTAAGAAATGCACTGTCTTTCACATTCATCTGACTAATTGAAATCCATTTATGTAGA ATATAGGAATGGGGGGTGATTCTGAAGTATCGGTCTGCTTGTATCTGTGAGCATATTCATTTGTATTTTAGGGTCTCTCTGCTTGCTGCT >In-frame_PSME3_ENST00000590720_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_2233nt AGTTTCCGGCGTGAGCGGCGAAAGCCGGGAGGGCGAGCGAGAGAGCAAGCAGGCAGCAGGCTGCCGGCGGGCGGGCGGACGGCACAGAGG GAGGGAGCGAGCGAGCAGTGAGTAAGCCAGCAAGGGCGGTCGGGTCCCGAGGTCAGCCGAGATTTCTCAGGTCCCTCCGGCCCCCTCCCT GGAGTCCACAGCGCCTCCGGTGTCCAGAGGATCGGACACGGCCCGGCCCGGCCATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGC TCAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGGCAGAAGACTTGGTGGCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATA GTTTTCTGAAGGAACCAATCTTAAACATCCATGACCTAACTCAGATCCACTCTGACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCA CCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGATGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTG TGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAGAAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAAT GTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTG CAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAA TAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAG AGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCTTTTGGTTTGTTACCAAAATATACAGTGTGGTGAAGGTTGACTGAAGAAG TCCAGTGTGTCCAGTTAAAACAGAAATAAATTAAACTCTTCATCAACAAAGACCTGTTTTTGTGACTGCCTTGAGTTTTATCAGAATTAT TGGCCTAGTAATCCTTCAGAAACACCGTAATTCTAAATAAACCTCTTCCCATACACCTTTCCCCCATAAGATGTGTCTTCAACACTATAA AGCATTTGTATTGTGATTTGATTAAGTATATATTTGGTTGTTCTCAATGAAGAGCAAATTTAAATATTATGTGCATTTGTAAATACAGTA GCTATAAAATTTTCCATACTTCTAATGGCAGAATAGAGGAGGCCATATTAAATAATACTGATGAAAGGCAGGACACTGCATTGTAAATAG GATTTTCTAGGCTCGGTAGGCAGAAAGAATTATTTTTCTTTGAAGGAAATAACTTTTTATCATGGTAATTTTGAAGGATGATTCCTATGA TGTGTTCACCAGGGGAATGTGGCTTTTAAAGAAAATCTTCTATTGGTTGTAACTGTTCATATCTTCTTACTTTTCTGTGTTGACTTCATT ATTCCCATGGTATTGGCCTTTTAAACTATGTGCCTCTGAGTCTTTCAATTTATAAATTTGTTATCTTAATAAATATTATAAAAATGTCTT CATTGCATCATTACCTATTATATATTCAAGGAGGTTCTGTAAATACAGATCTATTTACCAAGGTGTTTTGAAATGATTTATACTATTTTA TCAGATTTTACTGGATTTTGTTAATGTAACACTTTCTGAGTTTTGATCTGAATGGAATTTCACTGTGTAAGGCATTGTCTAAAATGTTCA CTGTGAGGCAGTAGAGGAGGTTGAAGTCATGCATATCTAGACAGATGAATTATCTGCAAGTACTTAAGGTGGAGCCTTACTACATTGTCA TTAAGGAGTTTCTATTTTTGACTTGTTTTTCAAAATACAGTGTTTTAAGTCAGGTTTTATTACCTGGACATTAGCAATCACTAGCAAGTC TTCATCTTTATGATTTCATTGTTTTAATTTAGATTTCACAAACAGTTTTACTTCTAAGAGTTAAGAAATGCACTGTCTTTCACATTCATC TGACTAATTGAAATCCATTTATGTAGAATATAGGAATGGGGGGTGATTCTGAAGTATCGGTCTGCTTGTATCTGTGAGCATATTCATTTG >In-frame_PSME3_ENST00000441946_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_2541nt GAAAGCCGGGAGGGCGAGCGAGAGAGCAAGCAGGCAGCAGGCTGCCGGCGGGCGGGCGGACGGCACAGAGGGAGGGAGCGAGCGAGCAGT GAGTAAGCCAGCAAGGGCGGTCGGGTCCCGAGGTCAGCCGAGATTTCTCAGGTCCCTCCGGCCCCCTCCCTGGAGTCCACAGCGCCTCCG GTGTCCAGAGGATCGGACACGGCCCGGCCCGGCCATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGCTCAAGCTCTGAGCTTCCGC TCGGCTCAGCCCAGCCCCCAACTCCCGGGGTCGGCTTCGCGGGAGAGGAAAATATAGGATGGCTTTCTGTACCGCGTCTGATGATGGAGA GTCCCGGGGACACCTCCGCGGACACGTGTTGGACTCAGGGCTTTAGGCCCGTGACAGCTGACAGCTTCAGACACAGGAGGAAGGGAGGGA AGGGGGAGGACAGAGGAGACAGGCAGGTGCTGTCCTCAAAGCCCTGCGTTCTTCTGAGATGGAAAAATGGATCCTCAAAAAAATAAAGTA TTTGCAGTCTGGGGGCCTCTCAGCTTCTTATTACAGTTACAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGGCAGAAGACTTGGT GGCAAATTTTTTCCCAAAGAAGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATCTTAAACATCCATGACCTAACTCAGATCCACTC TGACATGAATCTCCCAGTCCCTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGA TGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGA GAAAGTGAAACCTGAGATCCGGCTGTTGATTGAGAAATGTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGG AAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTC TAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGA TGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCTTTTGGTTTGTT ACCAAAATATACAGTGTGGTGAAGGTTGACTGAAGAAGTCCAGTGTGTCCAGTTAAAACAGAAATAAATTAAACTCTTCATCAACAAAGA CCTGTTTTTGTGACTGCCTTGAGTTTTATCAGAATTATTGGCCTAGTAATCCTTCAGAAACACCGTAATTCTAAATAAACCTCTTCCCAT ACACCTTTCCCCCATAAGATGTGTCTTCAACACTATAAAGCATTTGTATTGTGATTTGATTAAGTATATATTTGGTTGTTCTCAATGAAG AGCAAATTTAAATATTATGTGCATTTGTAAATACAGTAGCTATAAAATTTTCCATACTTCTAATGGCAGAATAGAGGAGGCCATATTAAA TAATACTGATGAAAGGCAGGACACTGCATTGTAAATAGGATTTTCTAGGCTCGGTAGGCAGAAAGAATTATTTTTCTTTGAAGGAAATAA CTTTTTATCATGGTAATTTTGAAGGATGATTCCTATGATGTGTTCACCAGGGGAATGTGGCTTTTAAAGAAAATCTTCTATTGGTTGTAA CTGTTCATATCTTCTTACTTTTCTGTGTTGACTTCATTATTCCCATGGTATTGGCCTTTTAAACTATGTGCCTCTGAGTCTTTCAATTTA TAAATTTGTTATCTTAATAAATATTATAAAAATGTCTTCATTGCATCATTACCTATTATATATTCAAGGAGGTTCTGTAAATACAGATCT ATTTACCAAGGTGTTTTGAAATGATTTATACTATTTTATCAGATTTTACTGGATTTTGTTAATGTAACACTTTCTGAGTTTTGATCTGAA TGGAATTTCACTGTGTAAGGCATTGTCTAAAATGTTCACTGTGAGGCAGTAGAGGAGGTTGAAGTCATGCATATCTAGACAGATGAATTA TCTGCAAGTACTTAAGGTGGAGCCTTACTACATTGTCATTAAGGAGTTTCTATTTTTGACTTGTTTTTCAAAATACAGTGTTTTAAGTCA GGTTTTATTACCTGGACATTAGCAATCACTAGCAAGTCTTCATCTTTATGATTTCATTGTTTTAATTTAGATTTCACAAACAGTTTTACT TCTAAGAGTTAAGAAATGCACTGTCTTTCACATTCATCTGACTAATTGAAATCCATTTATGTAGAATATAGGAATGGGGGGTGATTCTGA AGTATCGGTCTGCTTGTATCTGTGAGCATATTCATTTGTATTTTAGGGTCTCTCTGCTTGCTGCTTAGGAGAGCAAATCAGATACTGTCA >In-frame_PSME3_ENST00000293362_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_2200nt GGGCGGACGGCACAGAGGGAGGGAGCGAGCGAGCAGTGAGTAAGCCAGCAAGGGCGGTCGGGTCCCGAGGTCAGCCGAGATTTCTCAGGT CCCTCCGGCCCCCTCCCTGGAGTCCACAGCGCCTCCGGTGTCCAGAGGATCGGACACGGCCCGGCCCGGCCATGGCCTCGTTGCTGAAGG TGGATCAGGAAGTGAAGCTCAAGGTTGATTCTTTCAGGGAGCGGATCACAAGTGAGGCAGAAGACTTGGTGGCAAATTTTTTCCCAAAGA AGTTATTAGAACTTGATAGTTTTCTGAAGGAACCAATCTTAAACATCCATGACCTAACTCAGATCCACTCTGACATGAATCTCCCAGTCC CTGACCCCATTCTTCTCACCAATAGCCATGATGGACTGGATGGTCCCACTTATAAGAAGCGAAGGTTGGATGAGTGTGAAGAAGCCTTCC AAGGAACCAAGGTGTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAGAAAGTGAAACCTGAGATCC GGCTGTTGATTGAGAAATGTAACACGCCTTCAGGCAAAGGTCCTCATATATGTTTTGACCTCCAGGTCAAAATGTGGGTACAGCTCCTGA TTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAACAGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCAT CTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTCTAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCC GCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCATATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTT TGCATGCTTTTGGTTTGTTACCAAAATATACAGTGTGGTGAAGGTTGACTGAAGAAGTCCAGTGTGTCCAGTTAAAACAGAAATAAATTA AACTCTTCATCAACAAAGACCTGTTTTTGTGACTGCCTTGAGTTTTATCAGAATTATTGGCCTAGTAATCCTTCAGAAACACCGTAATTC TAAATAAACCTCTTCCCATACACCTTTCCCCCATAAGATGTGTCTTCAACACTATAAAGCATTTGTATTGTGATTTGATTAAGTATATAT TTGGTTGTTCTCAATGAAGAGCAAATTTAAATATTATGTGCATTTGTAAATACAGTAGCTATAAAATTTTCCATACTTCTAATGGCAGAA TAGAGGAGGCCATATTAAATAATACTGATGAAAGGCAGGACACTGCATTGTAAATAGGATTTTCTAGGCTCGGTAGGCAGAAAGAATTAT TTTTCTTTGAAGGAAATAACTTTTTATCATGGTAATTTTGAAGGATGATTCCTATGATGTGTTCACCAGGGGAATGTGGCTTTTAAAGAA AATCTTCTATTGGTTGTAACTGTTCATATCTTCTTACTTTTCTGTGTTGACTTCATTATTCCCATGGTATTGGCCTTTTAAACTATGTGC CTCTGAGTCTTTCAATTTATAAATTTGTTATCTTAATAAATATTATAAAAATGTCTTCATTGCATCATTACCTATTATATATTCAAGGAG GTTCTGTAAATACAGATCTATTTACCAAGGTGTTTTGAAATGATTTATACTATTTTATCAGATTTTACTGGATTTTGTTAATGTAACACT TTCTGAGTTTTGATCTGAATGGAATTTCACTGTGTAAGGCATTGTCTAAAATGTTCACTGTGAGGCAGTAGAGGAGGTTGAAGTCATGCA TATCTAGACAGATGAATTATCTGCAAGTACTTAAGGTGGAGCCTTACTACATTGTCATTAAGGAGTTTCTATTTTTGACTTGTTTTTCAA AATACAGTGTTTTAAGTCAGGTTTTATTACCTGGACATTAGCAATCACTAGCAAGTCTTCATCTTTATGATTTCATTGTTTTAATTTAGA TTTCACAAACAGTTTTACTTCTAAGAGTTAAGAAATGCACTGTCTTTCACATTCATCTGACTAATTGAAATCCATTTATGTAGAATATAG GAATGGGGGGTGATTCTGAAGTATCGGTCTGCTTGTATCTGTGAGCATATTCATTTGTATTTTAGGGTCTCTCTGCTTGCTGCTTAGGAG >In-frame_PSME3_ENST00000592169_chr17_40991397_+_TM9SF2_ENST00000376387_chr13_100214945_+_1968nt CGAGCGAGCAGTGAGTAAGCCAGCAAGGGCGGTCGGGTCCCGAGGTCAGCCGAGATTTCTCAGGTCCCTCCGGCCCCCTCCCTGGAGTCC ACAGCGCCTCCGGTGTCCAGAGGATCGGACACGGCCCGGCCCGGCCATGGCCTCGTTGCTGAAGGTGGATCAGGAAGTGAAGCTCAAGGT TGATTCTTTCAGGGAGCGGATCACAAGTGAGCCCACTTATAAGAAGCGAAGGTTGGATGAGTGTGAAGAAGCCTTCCAAGGAACCAAGGT GTTTGTGATGCCCAATGGGATGCTGAAAAGCAACCAGCAGCTGGTGGACATTATTGAGAAAGTGAAACCTGAGATCCGGCTGTTGATTGA GAAATGTAACACGGTCAAAATGTGGGTACAGCTCCTGATTCCCAGGATAGAAGATGGAAACAACTTTGGGGTGTCCATTCAGGAGGAAAC AGTTGCAGAGCTAAGAACTGTTGAGAGTGAAGCTGCATCTTATCTGGACCAGATTTCTAGATATTATATTACAAGAGCCAAATTGGTTTC TAAAATAGCTAAATATCCCCATGTGGAGGACTATCGCCGCACCGTGACAGAGATTGATGAGAAAGAATATATCAGCCTTCGGCTCATCAT ATCAGAGCTGAGGAATCAATATGAACAATTGGCTTCTTTGCATGCTTTTGGTTTGTTACCAAAATATACAGTGTGGTGAAGGTTGACTGA AGAAGTCCAGTGTGTCCAGTTAAAACAGAAATAAATTAAACTCTTCATCAACAAAGACCTGTTTTTGTGACTGCCTTGAGTTTTATCAGA ATTATTGGCCTAGTAATCCTTCAGAAACACCGTAATTCTAAATAAACCTCTTCCCATACACCTTTCCCCCATAAGATGTGTCTTCAACAC TATAAAGCATTTGTATTGTGATTTGATTAAGTATATATTTGGTTGTTCTCAATGAAGAGCAAATTTAAATATTATGTGCATTTGTAAATA CAGTAGCTATAAAATTTTCCATACTTCTAATGGCAGAATAGAGGAGGCCATATTAAATAATACTGATGAAAGGCAGGACACTGCATTGTA AATAGGATTTTCTAGGCTCGGTAGGCAGAAAGAATTATTTTTCTTTGAAGGAAATAACTTTTTATCATGGTAATTTTGAAGGATGATTCC TATGATGTGTTCACCAGGGGAATGTGGCTTTTAAAGAAAATCTTCTATTGGTTGTAACTGTTCATATCTTCTTACTTTTCTGTGTTGACT TCATTATTCCCATGGTATTGGCCTTTTAAACTATGTGCCTCTGAGTCTTTCAATTTATAAATTTGTTATCTTAATAAATATTATAAAAAT GTCTTCATTGCATCATTACCTATTATATATTCAAGGAGGTTCTGTAAATACAGATCTATTTACCAAGGTGTTTTGAAATGATTTATACTA TTTTATCAGATTTTACTGGATTTTGTTAATGTAACACTTTCTGAGTTTTGATCTGAATGGAATTTCACTGTGTAAGGCATTGTCTAAAAT GTTCACTGTGAGGCAGTAGAGGAGGTTGAAGTCATGCATATCTAGACAGATGAATTATCTGCAAGTACTTAAGGTGGAGCCTTACTACAT TGTCATTAAGGAGTTTCTATTTTTGACTTGTTTTTCAAAATACAGTGTTTTAAGTCAGGTTTTATTACCTGGACATTAGCAATCACTAGC AAGTCTTCATCTTTATGATTTCATTGTTTTAATTTAGATTTCACAAACAGTTTTACTTCTAAGAGTTAAGAAATGCACTGTCTTTCACAT TCATCTGACTAATTGAAATCCATTTATGTAGAATATAGGAATGGGGGGTGATTCTGAAGTATCGGTCTGCTTGTATCTGTGAGCATATTC |
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FusionGenePPI for PSME3_TM9SF2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PSME3 | FXR2, WDR25, ZCCHC10, KANSL1, NUDT18, BBS2, SERF2, PSME3, ITPKB, MCC, RNPS1, ATP5B, ADAP1, HSPA5, MDM2, TP53, CDKN1A, CDKN2A, BAP1, TAF1D, USP43, WDR48, SLX1B, UBC, SMURF1, NCOA3, DTNBP1, TBXA2R, PML, CHEK2, PARD3, AICDA, PSMD4, ATN1, COIL, PSMA1, PSMA7, PSMB1, PSMB4, PSMA5, PSMB3, PSMA4, PSMA6, PSMB2, PSMD11, PSMC5, PSMD1, PSMD2, PSMD8, PSMC2, PSMD12, PSMA8, MYH9, VCAM1, ITGA4, CBX2, CBX4, PARK2, NPM1, BAG3, CLK3, CLK2, YWHAQ, C1QBP, ADARB2, GTPBP4, SHFM1, PSMD14, CREBBP, SIRT1, PRKAB2, TUBGCP3, HUWE1, PFDN5, SPG7, DIP2A, FBXO7, TXN2, PRR13, EAF1, TNFAIP8L1, MOV10, NXF1, CAMTA2, FAM192A, TSHZ3, CSRP2BP, YEATS2, PRR14L, SALL2, SNAPC4, ZKSCAN1, ZNF324, THAP11, FLYWCH2, GATAD2A, SNAPC1, MGA, CHD8, ZBTB9, STRBP, ZZZ3, TSR1, TRMT6, GTF2F1, DIEXF, L3MBTL2, MBTD1, TADA2A, FBXL19, RALY, ELF2, ZNF891, TRIM33, MBIP, PCGF6, RAD18, RTEL1, SNAPC3, RAB40A, CMSS1, RSRP1, LIG3, RAB40AL, LUC7L, PSMB9, CCAR2, AHCYL1, HDGF, HIBCH, AHNAK, ARHGEF2, NUP50, PSMA2, PSMA3, SF3A3, SF3B2, SRRT, SRSF2, SF3B3, SF3B5, SFN, MED4, LCA5, EAF2, DEPTOR, ZNF526, KLF2, PIAS1, UBE2I, HYPK, CDC25B, RASL10B, RPL15, MRPS34, CCDC69, TP53TG5, KLHDC8A, HUS1B, TSPYL6, ZMAT5, SSH3, PPM1E, GATAD2B, TSPYL1, DLD, HSD17B10, TRIM25, BRCA1 | TM9SF2 | UNC93B1, SRSF7, RPN2, SLC25A3, MMGT1, SMAD4, ATP1B3, TCTN3, PTAR1, TMPRSS11B, SLC22A9, TTC30B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PSME3_TM9SF2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PSME3_TM9SF2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PSME3 | C0019693 | HIV Infections | 1 | CTD_human |
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