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Fusion gene ID: 29100 |
FusionGeneSummary for PSKH1_C16orf87 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PSKH1_C16orf87 | Fusion gene ID: 29100 | Hgene | Tgene | Gene symbol | PSKH1 | C16orf87 | Gene ID | 5681 | 388272 |
| Gene name | protein serine kinase H1 | chromosome 16 open reading frame 87 | |
| Synonyms | - | - | |
| Cytomap | 16q22.1 | 16q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase H1PSK-H1 | UPF0547 protein C16orf87 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | P11801 | Q6PH81 | |
| Ensembl transtripts involved in fusion gene | ENST00000291041, ENST00000575198, | ENST00000394806, ENST00000285697, ENST00000564250, | |
| Fusion gene scores | * DoF score | 5 X 2 X 4=40 | 2 X 1 X 2=4 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/40*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: PSKH1 [Title/Abstract] AND C16orf87 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-A6-6650-01B | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000291041 | ENST00000394806 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| In-frame | ENST00000291041 | ENST00000285697 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| 5CDS-5UTR | ENST00000291041 | ENST00000564250 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| intron-3CDS | ENST00000575198 | ENST00000394806 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| intron-3CDS | ENST00000575198 | ENST00000285697 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
| intron-5UTR | ENST00000575198 | ENST00000564250 | PSKH1 | chr16 | 67943609 | + | C16orf87 | chr16 | 46858394 | - |
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FusionProtFeatures for PSKH1_C16orf87 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PSKH1 | C16orf87 |
| May be a SFC-associated serine kinase (splicing factorcompartment-associated serine kinase) with a role in intranuclearSR protein (non-snRNP splicing factors containing aserine/arginine-rich domain) trafficking and pre-mRNA processing.{ECO:0000269|PubMed:12466556}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PSKH1 | chr16:67943609 | chr16:46858394 | ENST00000291041 | + | 2 | 3 | 104_112 | 319 | 425 | Nucleotide binding | ATP |
| Tgene | >C16orf87 | chr16:67943609 | chr16:46858394 | ENST00000285697 | - | 0 | 4 | 104_132 | 22 | 155 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >C16orf87 | chr16:67943609 | chr16:46858394 | ENST00000394806 | - | 0 | 3 | 104_132 | 22 | 94 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PSKH1 | chr16:67943609 | chr16:46858394 | ENST00000291041 | + | 2 | 3 | 98_355 | 319 | 425 | Domain | Protein kinase |
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FusionGeneSequence for PSKH1_C16orf87 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_391aa MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKF DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL FDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTEKQEKEIDI >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_452aa MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKF DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL FDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRR RTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSASAKKHEEEREKQEKEIDIYANLSDEKAFVFSVALAEINRKIINQRLI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_1173nt ATGGGCTGTGGGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACT AAGAGTGACGTGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACAC CCCTGCCCCGGTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTT GACCCACGTGTTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACC CGGCAGCCGTATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTG CGTCATGCCAACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTC TTTGACCGCATCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCAT GCACTGGGCATCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTC GGCCTGGCCAGTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTC CGCAAGCCATACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGAC AACCGTACCCGGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGT TACATATTTATTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAGAAACAGGAAAAGGAAATTGACATC TATGCTAACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTC >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_1356nt ATGGGCTGTGGGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACT AAGAGTGACGTGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACAC CCCTGCCCCGGTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTT GACCCACGTGTTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACC CGGCAGCCGTATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTG CGTCATGCCAACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTC TTTGACCGCATCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCAT GCACTGGGCATCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTC GGCCTGGCCAGTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTC CGCAAGCCATACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGAC AACCGTACCCGGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGT TACATATTTATTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAAAACAAGCATGAGGCCAAGAGGAGG CGAACAGAGAGAGTTAGGAGAGAGAAGATAAATTCTACAGTAAATAAAGATTTAGAAAACAGAAAGAGGTCTCGAAGTAACAGCCATTCA GATCATATCAGACGAGGAAGAGGAAGACCTAAAAGTGCATCTGCCAAAAAACATGAGGAAGAAAGAGAGAAACAGGAAAAGGAAATTGAC ATCTATGCTAACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_7688nt GAGAATGGCGGCGGCGGCGGCGGCGGCGGCGGCCGCTGCCATTGCCCGGAGATGGCCGGCAGAGCCGCCGAGACGCCGAAGAGCCCGCCG CCCGCGCGAGGTGTAGACGGGGCACTGCCTTCAGAGCAGGTCCTGCCAGCCTCGCTGGAGAGGATGCCCTCGTGTCCGTGATGGGCTGTG GGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACTAAGAGTGACG TGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACACCCCTGCCCCG GTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTTGACCCACGTG TTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACCCGGCAGCCGT ATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTGCGTCATGCCA ACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTCTTTGACCGCA TCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCATGCACTGGGCA TCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTCGGCCTGGCCA GTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTCCGCAAGCCAT ACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGACAACCGTACCC GGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGTTACATATTTA TTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAGAAACAGGAAAAGGAAATTGACATCTATGCTAACC TGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTCTGATACTTGT TTGCAAAATCTGCTGAAACTTCTGTCAGGATAACATCAGCAAATTCTCAAACAGTTATGGACTCTCAGGAGCATTCTGACTGCATCAATA AGGGCCATCGATTGTTTCTTTCTCGCCTGTCGTTTAGCCTGTGCCACACTTCGGGAGCAAAGCTGTGTAGGCTTGGACTGTTCTGGGATT TCCTTGTTTACCAAGGAGTATTGTCAGTGTTTTGTGTTTGGGATATAAGTAAGTGTATTTGCCAACAACAAAAAAAAACCAACAAAAATG CTGGATGGATGTTAAAGGATAAAAAGTGATGGGGTATGGGGTAGGTATGAAAACTAGGGTAATAAGATGCTTGATTGTTTTCAGGTTTGC CACCAGAGATGCAATATTTTAAATACTGTCAGAAAGAGTGATTTTTAAAAATATATATTTCAGATTTTCAGTGCTAACAGATTGCATATA TACAGTTCATTTACTTTTATTAAATTGGCAATCGATATTTTATTGAATGGGGAATTAAGAATATAAACTGTAAATTTTGTCTTAAATTGA TTTTTTTTCTTGGCCTTTATTTTTATTACTTAAGGTATGAGTTATATTTTAGGAGATACTTTCTAGACAGTTTGAAGTTTGGGTGCTATA TGAAGAAAAACATTTAATGATATACTCAGATATAAACACCTTGTTTTCTTGAATGTAATTTATTTATTAGCTAAAAAAAAAAAACAAACT GCTCTCAAGATGGTGCCTGTTAACCTAAACATGAAATATATTTATTACATGCAAAATATTTCTTAGCCACTTTTAAGCAGTAATGTTTTA TCTGAATGGATATTTGTTTCTATATCCTGATAATTATTTAAATTGTTACTTTCAATCTGGAAGAAAAAATAAACCTTAATATTGAAACTA AGTAGATTAAATAGTGTGATAAAAGTTTTTTGTTCTGGTGAAGTTTGTGAAATATATTTAAATTCTTAATTTTTCTAGTGTTAAGTCATA ATCGTTTATAGTTGATTTATATTAAATGCTTTTGCATTTTGGCATATCAATTTAATGATTAACATATTCAAACTTGGTAATCACTCCCCT TATTTTCAGTCGCTCTTCCCCCAATCTGTTTAGAAATCCTTTTAAAGCCTTCTTACAGAAGATAGTCATCAGTTAGATTTAGCCCCCTTT TAAGAGAATCTCCCTTTCAATTTTAGCCGTAACATTATCAATTTCAGACTTCATCCTGCATCTCCCATCACCTCCTCAAAGAAAAAAGGT CAACATTTTTTCCTACTTTATTTAAATGGTAACCAGCAGAGGGAGCTTAAGAGGTACTCTAGATAGGATAAAGAATTTTCCTAAGGATTC CTTTTCCTTTAATCCCTGTATCTATCTGCAGGTACTACTGCAACTATTTTGTATGCATTTTATTTATTTATTTAGGAGACAGAGTCTTGC TCGGTCGCCCAGGCTGGAGTGCAGTGGCACTGTCTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTTATGCCTCAGCCTC CTGAGTAGCTGTGACTAGAGGCGTGCGCCACCACGCCTGGCTGTTTTTTTTTTTGTATTTTTTAGTACAGATGGGGTCTCAGCATGTTGG CCAGGCTGGTCTCAAATTCCTGGCCTTAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACTCA GCCTTGTGTGCGTTTTAGAGTCTTAACTAGTAGTTTCCCCAATAATGTAATGTGATTTTATCTTTGAAACATACTGTAAGGAAACTTTTG ATTTTAAGTAAAAAAGCTTAAAAATGATTAATATCTAAAAATGCTTGTATACATATATATGTCCTCAGAAAAAGCAAGAACAGCTTGTGG AATAAGCACGTCTTTAAGGAATTATCGATGTCAGAGTCTATCCATTTAAAGCTGAAGACCATTACAGGAAAGTCATGTTAAAATATTCAT TGGATATGGTAAAGGAGGTACTGGTGGCTGGGCTGGAGCTTGCCGTATAGAAAAGTAATTACTTCAGATCTCATAATGTTAAATTATTGG CTTATTTAAAAATTTCCGTGGCAGAGAGGCAAATTAGGTTTCCTCTGTGACATAACCTATTTAACCAATTTTTCAAAAAATTGTACTCTA TGAGCTTTCTTGTTATAAAGCTAAAAAATTTAATTTGTCTAGGCATGTTGTAATGGTCCCAGAAAATATTACTTTGTCACTGGTGTCAGA GAAACCTCTGTCATCAGCAGATGTCCTAAGAGTATAATTATAGTTCTTTACTTAATCCAAAATTTGTTCTGCTCTGATATCTATAAATGA TATGATTATTCAAAATACCTTGAAATGATTCCACAATTAGATTAGGTCTGTTGAAGATAACTTATTCTTAAATATGAGTAAGATTAAATA AAAGTAGTTTGAGAGTTGTTACTCCCTGCCTCAACTCCATGGTATTCCAAAATGTTTTTGTGGGCACTTTAATACTTGTAGTTTGATTTT GTTTGTTAGTTTTAGAAATGAACATTTCTTAGATTTTCATGGGTATTTTTTGGCTGTATTTAAATGTAAATGATATAAAAGTAAGGGAAA TTGTGCAAATTATTTCTTGTGTAGTAATCAGTGGAAGTGATCAAACAGCTTGAAGCAGTTTATGATGAGAAAATTTAAAATTGCAAATGA CCTGAAAATTTAGCCAGTCTATTCTTATTTCTTTAAATTTCAGAAATACTTAAGAAAAAAAAAAAAAAGGTCAGTATGACCTCTGAGTTG CTTCCTAAAAGTAATCAGATAGTGTTCTCCCTCAGATAAGATTTCAAATTGAAAAGTATTTGACTTCTTTAACTCTAGTAATTGCACTTG ATTCTCTAATTCTGATCATTAAAATGACTTGGCAATATTTAATTTTGGCTTGCCTTTCAATCTGCATGTTTGTCTTAAATTTAGAAAAAT TAAGCTCTTTACTTACTTTTATATAAAGTATTAATTGGCCAGGCATGGTGGCTTACACCTGTAATCCCAACACTTTGGGAGGCCAAGGCA GGAGAGTTGTTTGAAGCCAGGAGTTTGAGACCAGCCTGGGCAACATGATGAGACCGCGTCTCTACAAAAAGTAAAATTAGCTGGGTGTGG TGCTTCCAGCTACTAGGCAGCTGAGGCTAAAGGATCACTTGAGCCCAGGAGTTCGAGGCTGCAGTGAGTGATGATCTTGCCACTGCACTC CAGCCTGGGAGGCAGAGCAAGAAACACCCTGTGTGAAAAAAGTATTGAATTTGTTTGATTCCACTTTCAAAATATGCTCTAGATACAGGT AGTCATTCTGCCAAATTGTGTTCTTCTCTAAAACATTTTGTCCGTCATTCTTTGAAACTCATTCTTAATTATTTCCACTTTACCTTCTAG TTTGGTTTGATGCCTTATATTCTTGCTAGTTAAAAGCATTTTTTCCCTAGTATTTTCTGTCTTTCTAGCCTTTAAGGCATATTGTTGTTA ACAAATCTCTTATTTAAGTTAATTAAAGTTTTTTCTGTGCAGCTGGGTTTTTTCTTTTACTACATGACAAGCTTCATTTTTACATTTGGA AGTACATGTATATATGTTTATATATTTTTATTCTCAGGATCTATTTTCTAGGGAACTATTTTTTTAAATTATTCTTTTGTGCTGCCTTAA CCCATTTATTATAGTTTGAATATTAGTAGTACTTACTACTCAAAGATTACAACTATACTAATAACTATCCTAACATACAAAGCAGACTCT CCAGGATTAAAAGTATGAGACATATAACAGAGTCTGGAATAGAATAATTCTTTTTACCCCAGTCAAGTATTTGCCTTTTGCATTATTAAG GAATCTGTTTTGTTCTTTTATTGATAATTTCTATATTTTTTTCTTTGCCTTATTGCACTGGTTGGGACTTTTTGCCTTGATCCAGTTGTA GGGGGGAAACATTCAGTCATTAAGCATTAAATAACTTTGTTGTTGTTGTGGGCTTGAAAAAATACCCTTTAGTAGATTGAGGGTAGACTC TTTTATTTCTGCTTGTTGGAAGTTTTCTGTCAGGAACAGATGTTGAATTTTGTCAGATGCTTTTTCTGCATAATTGATAGGACCTTTTTT CTCCCCTTTAGAATGTTCATATGGTGAAACATACTGATAGCTTTTCTTTTCTTTTTTTTTTGACACGGAGTCTCACTCTGTCACCCAGGC TGGAGTGCAATGGTGCGATCTTGGCTCACTGCACCCTCTGCCTCTTGGGTTCAAGCTTCCCTCACCAGCCTCCCAAGTACCTGGGTATAC AGGTGTGCATCACCATGCCCGGCTAATTTTTGAATTTTTAGTAGAGATAGGTTTTTACCATGTTGGCCAGGCTGGTCTTCAACTCCTGAC TCAGCCTCCCAAAGTGTTGGGATTACAGTCTCGCTCTGTCGCCCAGGCTGGAGGGCAGTGGTGTGATCTTGGCTCAATGCAACCTTGCAA CCTCTGCCTCCCGAGTTCAAGCGATTCTCCTGCCTTAGCCTCCTGAGTAGCTGGAATTACAGGCGCACGCCACTACACCCAGCTTCTTTT TGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAAGCTGGTCTCGAACTCCTGAGCTCCGGTGATCCACCCGCCTTTACAGGCAT GAGCCACCGTGCCCGGCTGCATTTCTCTTTTGTAAGAACCTGCTCTGGTTTATTGATATTTTGCTGTTTTTCTGTTTTAAGTTTCATTAA TTTCTGATCTTTAGTATTTTCTCCTTTCTTTGCTTTGGGCTTATTTGCTCCCTTTTCTAGCTTATTGTGGCGGAAGCTCAGATCATTGAT TTTAAAATTTACTTATTTATTTATTTATTTATTTAATTCAACACTGATCAGAAGGCTTTTTGTGCTTTTCTAAAAAAAGCATTTAATGCT ATAAATTTCCCATTTGCTTTATCTCACAAATTTTATTGTGTTGTAATTTTGTGTTCAATTTAGAATATTCTGATTTTTCTTGGTATTACT ATAATTTTCAAATATTTAGAGTTTTTTTCAGTTATCTTTCTGTTACTGATTGTAATTTATTGTTTTTTAAAATTATAGTTCTTTGAATAG TTTTGCAGTATTTGCTCTAGGGATTACTATAAACATACTTCACTTTTTACAGTTCACTTAGAAGTCAATATTTTACCAGTTCAAGTGGAA TGTAGAAAAATCTTACCACTGTTTACATTCCTTTACCCTCTCCCCTTTATGTTATAATTTTCTTATAAATCATAAGACTTGGCTGGGCAC AGTGGCTCACCTGTAATCCCAGGACTGGGAGGCCGAGGCGAGCAGATTGCTTAAGTCCAGGAGTTCGAGACCAGCCTGGACAATGTGGTG AAACCCCAACTCTACAAAAAATACACAAAATTAGCTAGGCGTGGTAGCATGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAAGTGGGAG GATTACTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATCACTCCACTCCACTCCAGCCTGAGTGACAGAGCTAGACACTGTGTCT CAAAAAATAAAAATAAAAAATAAGACTCATCAGATAATGTATTTTTTCCTTACAACTATCATAGATATTTTTAAGAACCCAAGAGGAAAA CAGTCTATCACATTTACCACAATATTTATCATTTGTATTAATCTTCCTTAATTCTTGATGTTCCAAGTTTACATAGGTATCAGTCCTTTT CATCTGGAAAATTTCTTTTAGTGCAGGTCTGTTGACATTTAATTCTCTTATTTTTTCTTCATCTGAGAATGTCTTTATTTTGCCTTAATT CATGAAAGATATTTTTGCTGGATATAAACTACTGTGTTGACAGTTCTTTCAGCCTCCATGGTTTCTGATGAGAAATGTGCAGCCATTAAA GTAATATTTCCCCTGTATGAAACATGTTATTTTTCTCTGAGTATTTTCAGGAATCTTTGTCTTTGGTTTTTATTGGTTTGATTATGATGT GCCCGGGTGTTTGAATTTATTCTCTTTGGGATTTGTTGAGCTTAAATGTGTAAGTTTATGCCTTTCATCAGATTATGTAAAGTTTTAAAC CATTCAGATATTTTCTGCTCTACTTTCTCCTCCCTCTTAGGCTCCAGTGATGCAAGTGTTAGACTCTTTGGTATTATCTCACAGATCTCA GAACCTCTGTTCATTTATTTTATTTTAATAAATCATTTCAGTTAACAAAATCATATATTGTATGCAGCATGATGTTTCAATATGTATGTT >In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_2384nt GAGAATGGCGGCGGCGGCGGCGGCGGCGGCGGCCGCTGCCATTGCCCGGAGATGGCCGGCAGAGCCGCCGAGACGCCGAAGAGCCCGCCG CCCGCGCGAGGTGTAGACGGGGCACTGCCTTCAGAGCAGGTCCTGCCAGCCTCGCTGGAGAGGATGCCCTCGTGTCCGTGATGGGCTGTG GGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACTAAGAGTGACG TGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACACCCCTGCCCCG GTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTTGACCCACGTG TTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACCCGGCAGCCGT ATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTGCGTCATGCCA ACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTCTTTGACCGCA TCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCATGCACTGGGCA TCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTCGGCCTGGCCA GTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTCCGCAAGCCAT ACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGACAACCGTACCC GGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGTTACATATTTA TTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAAAACAAGCATGAGGCCAAGAGGAGGCGAACAGAGA GAGTTAGGAGAGAGAAGATAAATTCTACAGTAAATAAAGATTTAGAAAACAGAAAGAGGTCTCGAAGTAACAGCCATTCAGATCATATCA GACGAGGAAGAGGAAGACCTAAAAGTGCATCTGCCAAAAAACATGAGGAAGAAAGAGAGAAACAGGAAAAGGAAATTGACATCTATGCTA ACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTCTGATACT TGTTTGCAAAATCTGCTGAAACTTCTGTCAGGATAACATCAGCAAATTCTCAAACAGTTATGGACTCTCAGGAGCATTCTGACTGCATCA ATAAGGGCCATCGATTGTTTCTTTCTCGCCTGTCGTTTAGCCTGTGCCACACTTCGGGAGCAAAGCTGTGTAGGCTTGGACTGTTCTGGG ATTTCCTTGTTTACCAAGGAGTATTGTCAGTGTTTTGTGTTTGGGATATAAGTAAGTGTATTTGCCAACAACAAAAAAAAACCAACAAAA ATGCTGGATGGATGTTAAAGGATAAAAAGTGATGGGGTATGGGGTAGGTATGAAAACTAGGGTAATAAGATGCTTGATTGTTTTCAGGTT TGCCACCAGAGATGCAATATTTTAAATACTGTCAGAAAGAGTGATTTTTAAAAATATATATTTCAGATTTTCAGTGCTAACAGATTGCAT ATATACAGTTCATTTACTTTTATTAAATTGGCAATCGATATTTTATTGAATGGGGAATTAAGAATATAAACTGTAAATTTTGTCTTAAAT TGATTTTTTTTCTTGGCCTTTATTTTTATTACTTAAGGTATGAGTTATATTTTAGGAGATACTTTCTAGACAGTTTGAAGTTTGGGTGCT ATATGAAGAAAAACATTTAATGATATACTCAGATATAAACACCTTGTTTTCTTGAATGTAATTTATTTATTAGCTAAAAAAAAAAAACAA ACTGCTCTCAAGATGGTGCCTGTTAACCTAAACATGAAATATATTTATTACATGCAAAATATTTCTTAGCCACTTTTAAGCAGTAATGTT |
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FusionGenePPI for PSKH1_C16orf87 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PSKH1 | CDC6, HSP90AA1, SNTA1, RDH13, NXF1, UNC119 | C16orf87 | ELAVL1, HDAC1, HDAC2, MAGEA12, MOV10, HIST1H2BA, MIER3, ANAPC2, MIER1, CDC16, ARID5B, NEK2, ANAPC4, CDC23, CDC27, MIER2, ANAPC5, ANAPC1, FZR1, H2AFX, ANAPC7, ANAPC16 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PSKH1_C16orf87 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PSKH1_C16orf87 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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