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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 29100

FusionGeneSummary for PSKH1_C16orf87

check button Fusion gene summary
Fusion gene informationFusion gene name: PSKH1_C16orf87
Fusion gene ID: 29100
HgeneTgene
Gene symbol

PSKH1

C16orf87

Gene ID

5681

388272

Gene nameprotein serine kinase H1chromosome 16 open reading frame 87
Synonyms--
Cytomap

16q22.1

16q11.2

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase H1PSK-H1UPF0547 protein C16orf87
Modification date2018051920180519
UniProtAcc

P11801

Q6PH81

Ensembl transtripts involved in fusion geneENST00000291041, ENST00000575198, 
ENST00000394806, ENST00000285697, 
ENST00000564250, 
Fusion gene scores* DoF score5 X 2 X 4=402 X 1 X 2=4
# samples 52
** MAII scorelog2(5/40*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(2/4*10)=2.32192809488736
Context

PubMed: PSKH1 [Title/Abstract] AND C16orf87 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVCOADTCGA-A6-6650-01BPSKH1chr16

67943609

+C16orf87chr16

46858394

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000291041ENST00000394806PSKH1chr16

67943609

+C16orf87chr16

46858394

-
In-frameENST00000291041ENST00000285697PSKH1chr16

67943609

+C16orf87chr16

46858394

-
5CDS-5UTRENST00000291041ENST00000564250PSKH1chr16

67943609

+C16orf87chr16

46858394

-
intron-3CDSENST00000575198ENST00000394806PSKH1chr16

67943609

+C16orf87chr16

46858394

-
intron-3CDSENST00000575198ENST00000285697PSKH1chr16

67943609

+C16orf87chr16

46858394

-
intron-5UTRENST00000575198ENST00000564250PSKH1chr16

67943609

+C16orf87chr16

46858394

-

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FusionProtFeatures for PSKH1_C16orf87


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PSKH1

P11801

C16orf87

Q6PH81

May be a SFC-associated serine kinase (splicing factorcompartment-associated serine kinase) with a role in intranuclearSR protein (non-snRNP splicing factors containing aserine/arginine-rich domain) trafficking and pre-mRNA processing.{ECO:0000269|PubMed:12466556}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePSKH1chr16:67943609chr16:46858394ENST00000291041+23104_112319425Nucleotide bindingATP
TgeneC16orf87chr16:67943609chr16:46858394ENST00000285697-04104_13222155Coiled coilOntology_term=ECO:0000255
TgeneC16orf87chr16:67943609chr16:46858394ENST00000394806-03104_1322294Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePSKH1chr16:67943609chr16:46858394ENST00000291041+2398_355319425DomainProtein kinase


Top

FusionGeneSequence for PSKH1_C16orf87


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_391aa
MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQTAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKF
DPRVTAKTDIKALIGRGSFSRVVRVEHRATRQPTAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL
FDRIIAKGSFTERDATRVLQMVLDGVRTLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV
RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTEKQEKEIDI

>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_452aa
MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQTAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKF
DPRVTAKTDIKALIGRGSFSRVVRVEHRATRQPTAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGEL
FDRIIAKGSFTERDATRVLQMVLDGVRTLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLV
RKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEVPVACKSCPCGYIFISRKLLNAKHSEKSPPSTENKHEAKRR
RTERVRREKINSTVNKDLENRKRSRSNSHSDHIRRGRGRPKSASAKKHEEEREKQEKEIDITANLSDEKAFVFSVALAEINRKIINQRLI


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_1173nt
ATGGGCTGTGGGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACT
AAGAGTGACGTGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACAC
CCCTGCCCCGGTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTT
GACCCACGTGTTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACC
CGGCAGCCGTATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTG
CGTCATGCCAACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTC
TTTGACCGCATCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCAT
GCACTGGGCATCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTC
GGCCTGGCCAGTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTC
CGCAAGCCATACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGAC
AACCGTACCCGGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGT
TACATATTTATTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAGAAACAGGAAAAGGAAATTGACATC
TATGCTAACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTC

>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_1356nt
ATGGGCTGTGGGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACT
AAGAGTGACGTGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACAC
CCCTGCCCCGGTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTT
GACCCACGTGTTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACC
CGGCAGCCGTATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTG
CGTCATGCCAACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTC
TTTGACCGCATCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCAT
GCACTGGGCATCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTC
GGCCTGGCCAGTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTC
CGCAAGCCATACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGAC
AACCGTACCCGGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGT
TACATATTTATTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAAAACAAGCATGAGGCCAAGAGGAGG
CGAACAGAGAGAGTTAGGAGAGAGAAGATAAATTCTACAGTAAATAAAGATTTAGAAAACAGAAAGAGGTCTCGAAGTAACAGCCATTCA
GATCATATCAGACGAGGAAGAGGAAGACCTAAAAGTGCATCTGCCAAAAAACATGAGGAAGAAAGAGAGAAACAGGAAAAGGAAATTGAC
ATCTATGCTAACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATT


* Fusion transcript sequences (Full-length transcript).
>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000394806_chr16_46858394_-_7688nt
GAGAATGGCGGCGGCGGCGGCGGCGGCGGCGGCCGCTGCCATTGCCCGGAGATGGCCGGCAGAGCCGCCGAGACGCCGAAGAGCCCGCCG
CCCGCGCGAGGTGTAGACGGGGCACTGCCTTCAGAGCAGGTCCTGCCAGCCTCGCTGGAGAGGATGCCCTCGTGTCCGTGATGGGCTGTG
GGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACTAAGAGTGACG
TGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACACCCCTGCCCCG
GTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTTGACCCACGTG
TTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACCCGGCAGCCGT
ATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTGCGTCATGCCA
ACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTCTTTGACCGCA
TCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCATGCACTGGGCA
TCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTCGGCCTGGCCA
GTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTCCGCAAGCCAT
ACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGACAACCGTACCC
GGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGTTACATATTTA
TTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAGAAACAGGAAAAGGAAATTGACATCTATGCTAACC
TGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTCTGATACTTGT
TTGCAAAATCTGCTGAAACTTCTGTCAGGATAACATCAGCAAATTCTCAAACAGTTATGGACTCTCAGGAGCATTCTGACTGCATCAATA
AGGGCCATCGATTGTTTCTTTCTCGCCTGTCGTTTAGCCTGTGCCACACTTCGGGAGCAAAGCTGTGTAGGCTTGGACTGTTCTGGGATT
TCCTTGTTTACCAAGGAGTATTGTCAGTGTTTTGTGTTTGGGATATAAGTAAGTGTATTTGCCAACAACAAAAAAAAACCAACAAAAATG
CTGGATGGATGTTAAAGGATAAAAAGTGATGGGGTATGGGGTAGGTATGAAAACTAGGGTAATAAGATGCTTGATTGTTTTCAGGTTTGC
CACCAGAGATGCAATATTTTAAATACTGTCAGAAAGAGTGATTTTTAAAAATATATATTTCAGATTTTCAGTGCTAACAGATTGCATATA
TACAGTTCATTTACTTTTATTAAATTGGCAATCGATATTTTATTGAATGGGGAATTAAGAATATAAACTGTAAATTTTGTCTTAAATTGA
TTTTTTTTCTTGGCCTTTATTTTTATTACTTAAGGTATGAGTTATATTTTAGGAGATACTTTCTAGACAGTTTGAAGTTTGGGTGCTATA
TGAAGAAAAACATTTAATGATATACTCAGATATAAACACCTTGTTTTCTTGAATGTAATTTATTTATTAGCTAAAAAAAAAAAACAAACT
GCTCTCAAGATGGTGCCTGTTAACCTAAACATGAAATATATTTATTACATGCAAAATATTTCTTAGCCACTTTTAAGCAGTAATGTTTTA
TCTGAATGGATATTTGTTTCTATATCCTGATAATTATTTAAATTGTTACTTTCAATCTGGAAGAAAAAATAAACCTTAATATTGAAACTA
AGTAGATTAAATAGTGTGATAAAAGTTTTTTGTTCTGGTGAAGTTTGTGAAATATATTTAAATTCTTAATTTTTCTAGTGTTAAGTCATA
ATCGTTTATAGTTGATTTATATTAAATGCTTTTGCATTTTGGCATATCAATTTAATGATTAACATATTCAAACTTGGTAATCACTCCCCT
TATTTTCAGTCGCTCTTCCCCCAATCTGTTTAGAAATCCTTTTAAAGCCTTCTTACAGAAGATAGTCATCAGTTAGATTTAGCCCCCTTT
TAAGAGAATCTCCCTTTCAATTTTAGCCGTAACATTATCAATTTCAGACTTCATCCTGCATCTCCCATCACCTCCTCAAAGAAAAAAGGT
CAACATTTTTTCCTACTTTATTTAAATGGTAACCAGCAGAGGGAGCTTAAGAGGTACTCTAGATAGGATAAAGAATTTTCCTAAGGATTC
CTTTTCCTTTAATCCCTGTATCTATCTGCAGGTACTACTGCAACTATTTTGTATGCATTTTATTTATTTATTTAGGAGACAGAGTCTTGC
TCGGTCGCCCAGGCTGGAGTGCAGTGGCACTGTCTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTTATGCCTCAGCCTC
CTGAGTAGCTGTGACTAGAGGCGTGCGCCACCACGCCTGGCTGTTTTTTTTTTTGTATTTTTTAGTACAGATGGGGTCTCAGCATGTTGG
CCAGGCTGGTCTCAAATTCCTGGCCTTAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACTCA
GCCTTGTGTGCGTTTTAGAGTCTTAACTAGTAGTTTCCCCAATAATGTAATGTGATTTTATCTTTGAAACATACTGTAAGGAAACTTTTG
ATTTTAAGTAAAAAAGCTTAAAAATGATTAATATCTAAAAATGCTTGTATACATATATATGTCCTCAGAAAAAGCAAGAACAGCTTGTGG
AATAAGCACGTCTTTAAGGAATTATCGATGTCAGAGTCTATCCATTTAAAGCTGAAGACCATTACAGGAAAGTCATGTTAAAATATTCAT
TGGATATGGTAAAGGAGGTACTGGTGGCTGGGCTGGAGCTTGCCGTATAGAAAAGTAATTACTTCAGATCTCATAATGTTAAATTATTGG
CTTATTTAAAAATTTCCGTGGCAGAGAGGCAAATTAGGTTTCCTCTGTGACATAACCTATTTAACCAATTTTTCAAAAAATTGTACTCTA
TGAGCTTTCTTGTTATAAAGCTAAAAAATTTAATTTGTCTAGGCATGTTGTAATGGTCCCAGAAAATATTACTTTGTCACTGGTGTCAGA
GAAACCTCTGTCATCAGCAGATGTCCTAAGAGTATAATTATAGTTCTTTACTTAATCCAAAATTTGTTCTGCTCTGATATCTATAAATGA
TATGATTATTCAAAATACCTTGAAATGATTCCACAATTAGATTAGGTCTGTTGAAGATAACTTATTCTTAAATATGAGTAAGATTAAATA
AAAGTAGTTTGAGAGTTGTTACTCCCTGCCTCAACTCCATGGTATTCCAAAATGTTTTTGTGGGCACTTTAATACTTGTAGTTTGATTTT
GTTTGTTAGTTTTAGAAATGAACATTTCTTAGATTTTCATGGGTATTTTTTGGCTGTATTTAAATGTAAATGATATAAAAGTAAGGGAAA
TTGTGCAAATTATTTCTTGTGTAGTAATCAGTGGAAGTGATCAAACAGCTTGAAGCAGTTTATGATGAGAAAATTTAAAATTGCAAATGA
CCTGAAAATTTAGCCAGTCTATTCTTATTTCTTTAAATTTCAGAAATACTTAAGAAAAAAAAAAAAAAGGTCAGTATGACCTCTGAGTTG
CTTCCTAAAAGTAATCAGATAGTGTTCTCCCTCAGATAAGATTTCAAATTGAAAAGTATTTGACTTCTTTAACTCTAGTAATTGCACTTG
ATTCTCTAATTCTGATCATTAAAATGACTTGGCAATATTTAATTTTGGCTTGCCTTTCAATCTGCATGTTTGTCTTAAATTTAGAAAAAT
TAAGCTCTTTACTTACTTTTATATAAAGTATTAATTGGCCAGGCATGGTGGCTTACACCTGTAATCCCAACACTTTGGGAGGCCAAGGCA
GGAGAGTTGTTTGAAGCCAGGAGTTTGAGACCAGCCTGGGCAACATGATGAGACCGCGTCTCTACAAAAAGTAAAATTAGCTGGGTGTGG
TGCTTCCAGCTACTAGGCAGCTGAGGCTAAAGGATCACTTGAGCCCAGGAGTTCGAGGCTGCAGTGAGTGATGATCTTGCCACTGCACTC
CAGCCTGGGAGGCAGAGCAAGAAACACCCTGTGTGAAAAAAGTATTGAATTTGTTTGATTCCACTTTCAAAATATGCTCTAGATACAGGT
AGTCATTCTGCCAAATTGTGTTCTTCTCTAAAACATTTTGTCCGTCATTCTTTGAAACTCATTCTTAATTATTTCCACTTTACCTTCTAG
TTTGGTTTGATGCCTTATATTCTTGCTAGTTAAAAGCATTTTTTCCCTAGTATTTTCTGTCTTTCTAGCCTTTAAGGCATATTGTTGTTA
ACAAATCTCTTATTTAAGTTAATTAAAGTTTTTTCTGTGCAGCTGGGTTTTTTCTTTTACTACATGACAAGCTTCATTTTTACATTTGGA
AGTACATGTATATATGTTTATATATTTTTATTCTCAGGATCTATTTTCTAGGGAACTATTTTTTTAAATTATTCTTTTGTGCTGCCTTAA
CCCATTTATTATAGTTTGAATATTAGTAGTACTTACTACTCAAAGATTACAACTATACTAATAACTATCCTAACATACAAAGCAGACTCT
CCAGGATTAAAAGTATGAGACATATAACAGAGTCTGGAATAGAATAATTCTTTTTACCCCAGTCAAGTATTTGCCTTTTGCATTATTAAG
GAATCTGTTTTGTTCTTTTATTGATAATTTCTATATTTTTTTCTTTGCCTTATTGCACTGGTTGGGACTTTTTGCCTTGATCCAGTTGTA
GGGGGGAAACATTCAGTCATTAAGCATTAAATAACTTTGTTGTTGTTGTGGGCTTGAAAAAATACCCTTTAGTAGATTGAGGGTAGACTC
TTTTATTTCTGCTTGTTGGAAGTTTTCTGTCAGGAACAGATGTTGAATTTTGTCAGATGCTTTTTCTGCATAATTGATAGGACCTTTTTT
CTCCCCTTTAGAATGTTCATATGGTGAAACATACTGATAGCTTTTCTTTTCTTTTTTTTTTGACACGGAGTCTCACTCTGTCACCCAGGC
TGGAGTGCAATGGTGCGATCTTGGCTCACTGCACCCTCTGCCTCTTGGGTTCAAGCTTCCCTCACCAGCCTCCCAAGTACCTGGGTATAC
AGGTGTGCATCACCATGCCCGGCTAATTTTTGAATTTTTAGTAGAGATAGGTTTTTACCATGTTGGCCAGGCTGGTCTTCAACTCCTGAC
TCAGCCTCCCAAAGTGTTGGGATTACAGTCTCGCTCTGTCGCCCAGGCTGGAGGGCAGTGGTGTGATCTTGGCTCAATGCAACCTTGCAA
CCTCTGCCTCCCGAGTTCAAGCGATTCTCCTGCCTTAGCCTCCTGAGTAGCTGGAATTACAGGCGCACGCCACTACACCCAGCTTCTTTT
TGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAAGCTGGTCTCGAACTCCTGAGCTCCGGTGATCCACCCGCCTTTACAGGCAT
GAGCCACCGTGCCCGGCTGCATTTCTCTTTTGTAAGAACCTGCTCTGGTTTATTGATATTTTGCTGTTTTTCTGTTTTAAGTTTCATTAA
TTTCTGATCTTTAGTATTTTCTCCTTTCTTTGCTTTGGGCTTATTTGCTCCCTTTTCTAGCTTATTGTGGCGGAAGCTCAGATCATTGAT
TTTAAAATTTACTTATTTATTTATTTATTTATTTAATTCAACACTGATCAGAAGGCTTTTTGTGCTTTTCTAAAAAAAGCATTTAATGCT
ATAAATTTCCCATTTGCTTTATCTCACAAATTTTATTGTGTTGTAATTTTGTGTTCAATTTAGAATATTCTGATTTTTCTTGGTATTACT
ATAATTTTCAAATATTTAGAGTTTTTTTCAGTTATCTTTCTGTTACTGATTGTAATTTATTGTTTTTTAAAATTATAGTTCTTTGAATAG
TTTTGCAGTATTTGCTCTAGGGATTACTATAAACATACTTCACTTTTTACAGTTCACTTAGAAGTCAATATTTTACCAGTTCAAGTGGAA
TGTAGAAAAATCTTACCACTGTTTACATTCCTTTACCCTCTCCCCTTTATGTTATAATTTTCTTATAAATCATAAGACTTGGCTGGGCAC
AGTGGCTCACCTGTAATCCCAGGACTGGGAGGCCGAGGCGAGCAGATTGCTTAAGTCCAGGAGTTCGAGACCAGCCTGGACAATGTGGTG
AAACCCCAACTCTACAAAAAATACACAAAATTAGCTAGGCGTGGTAGCATGTTCCTGTAGTCCCAGCTACTCAGGAGGCTGAAGTGGGAG
GATTACTTGAGCCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATCACTCCACTCCACTCCAGCCTGAGTGACAGAGCTAGACACTGTGTCT
CAAAAAATAAAAATAAAAAATAAGACTCATCAGATAATGTATTTTTTCCTTACAACTATCATAGATATTTTTAAGAACCCAAGAGGAAAA
CAGTCTATCACATTTACCACAATATTTATCATTTGTATTAATCTTCCTTAATTCTTGATGTTCCAAGTTTACATAGGTATCAGTCCTTTT
CATCTGGAAAATTTCTTTTAGTGCAGGTCTGTTGACATTTAATTCTCTTATTTTTTCTTCATCTGAGAATGTCTTTATTTTGCCTTAATT
CATGAAAGATATTTTTGCTGGATATAAACTACTGTGTTGACAGTTCTTTCAGCCTCCATGGTTTCTGATGAGAAATGTGCAGCCATTAAA
GTAATATTTCCCCTGTATGAAACATGTTATTTTTCTCTGAGTATTTTCAGGAATCTTTGTCTTTGGTTTTTATTGGTTTGATTATGATGT
GCCCGGGTGTTTGAATTTATTCTCTTTGGGATTTGTTGAGCTTAAATGTGTAAGTTTATGCCTTTCATCAGATTATGTAAAGTTTTAAAC
CATTCAGATATTTTCTGCTCTACTTTCTCCTCCCTCTTAGGCTCCAGTGATGCAAGTGTTAGACTCTTTGGTATTATCTCACAGATCTCA
GAACCTCTGTTCATTTATTTTATTTTAATAAATCATTTCAGTTAACAAAATCATATATTGTATGCAGCATGATGTTTCAATATGTATGTT

>In-frame_PSKH1_ENST00000291041_chr16_67943609_+_C16orf87_ENST00000285697_chr16_46858394_-_2384nt
GAGAATGGCGGCGGCGGCGGCGGCGGCGGCGGCCGCTGCCATTGCCCGGAGATGGCCGGCAGAGCCGCCGAGACGCCGAAGAGCCCGCCG
CCCGCGCGAGGTGTAGACGGGGCACTGCCTTCAGAGCAGGTCCTGCCAGCCTCGCTGGAGAGGATGCCCTCGTGTCCGTGATGGGCTGTG
GGACAAGCAAGGTCCTTCCCGAGCCACCCAAGGATGTCCAGCTGGATCTGGTCAAGAAGGTGGAGCCCTTCAGTGGCACTAAGAGTGACG
TGTACAAGCACTTCATCACAGAGGTGGACAGTGTTGGCCCTGTCAAAGCCGGGTTCCCAGCAGCAAGTCAGTATGCACACCCCTGCCCCG
GTCCCCCGACTGCTGGCCACACGGAGCCTCCCTCAGAACCACCACGCAGGGCCAGGGTAGCTAAGTACAGGGCCAAGTTTGACCCACGTG
TTACAGCTAAGTATGACATCAAGGCCCTAATTGGCCGAGGCAGCTTCAGCCGAGTGGTACGTGTAGAGCACCGGGCAACCCGGCAGCCGT
ATGCCATCAAGATGATTGAGACCAAGTACCGGGAGGGGCGGGAGGTGTGTGAGTCGGAGCTGCGTGTGCTGCGTCGGGTGCGTCATGCCA
ACATCATCCAGCTGGTGGAGGTGTTCGAGACACAGGAGCGGGTGTACATGGTGATGGAGCTGGCCACTGGTGGAGAGCTCTTTGACCGCA
TCATTGCCAAGGGCTCCTTCACCGAGCGTGACGCCACGCGGGTGCTGCAGATGGTGCTGGATGGCGTCCGGTATCTGCATGCACTGGGCA
TCACACACCGAGACCTCAAACCTGAGAATCTGCTCTACTACCATCCGGGCACTGACTCCAAGATCATCATCACCGACTTCGGCCTGGCCA
GTGCTCGCAAGAAGGGTGATGACTGCTTGATGAAGACCACCTGTGGCACGCCTGAGTACATTGCCCCAGAAGTCCTGGTCCGCAAGCCAT
ACACCAACTCAGTGGACATGTGGGCGCTGGGCGTCATTGCCTACATCCTACTCAGTGGCACCATGCCGTTTGAGGATGACAACCGTACCC
GGCTGTACCGGCAGATCCTCAGGGGCAAGTACAGTTACTCTGGGGAGGTTCCTGTTGCATGTAAATCATGTCCTTGTGGTTACATATTTA
TTAGCAGAAAACTTTTAAATGCAAAACACTCAGAGAAATCACCACCTTCTACAGAAAACAAGCATGAGGCCAAGAGGAGGCGAACAGAGA
GAGTTAGGAGAGAGAAGATAAATTCTACAGTAAATAAAGATTTAGAAAACAGAAAGAGGTCTCGAAGTAACAGCCATTCAGATCATATCA
GACGAGGAAGAGGAAGACCTAAAAGTGCATCTGCCAAAAAACATGAGGAAGAAAGAGAGAAACAGGAAAAGGAAATTGACATCTATGCTA
ACCTGTCTGATGAAAAGGCTTTCGTGTTTTCAGTCGCCTTGGCAGAAATAAATAGAAAAATTATCAATCAAAGACTTATTCTCTGATACT
TGTTTGCAAAATCTGCTGAAACTTCTGTCAGGATAACATCAGCAAATTCTCAAACAGTTATGGACTCTCAGGAGCATTCTGACTGCATCA
ATAAGGGCCATCGATTGTTTCTTTCTCGCCTGTCGTTTAGCCTGTGCCACACTTCGGGAGCAAAGCTGTGTAGGCTTGGACTGTTCTGGG
ATTTCCTTGTTTACCAAGGAGTATTGTCAGTGTTTTGTGTTTGGGATATAAGTAAGTGTATTTGCCAACAACAAAAAAAAACCAACAAAA
ATGCTGGATGGATGTTAAAGGATAAAAAGTGATGGGGTATGGGGTAGGTATGAAAACTAGGGTAATAAGATGCTTGATTGTTTTCAGGTT
TGCCACCAGAGATGCAATATTTTAAATACTGTCAGAAAGAGTGATTTTTAAAAATATATATTTCAGATTTTCAGTGCTAACAGATTGCAT
ATATACAGTTCATTTACTTTTATTAAATTGGCAATCGATATTTTATTGAATGGGGAATTAAGAATATAAACTGTAAATTTTGTCTTAAAT
TGATTTTTTTTCTTGGCCTTTATTTTTATTACTTAAGGTATGAGTTATATTTTAGGAGATACTTTCTAGACAGTTTGAAGTTTGGGTGCT
ATATGAAGAAAAACATTTAATGATATACTCAGATATAAACACCTTGTTTTCTTGAATGTAATTTATTTATTAGCTAAAAAAAAAAAACAA
ACTGCTCTCAAGATGGTGCCTGTTAACCTAAACATGAAATATATTTATTACATGCAAAATATTTCTTAGCCACTTTTAAGCAGTAATGTT


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FusionGenePPI for PSKH1_C16orf87


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PSKH1CDC6, HSP90AA1, SNTA1, RDH13, NXF1, UNC119C16orf87ELAVL1, HDAC1, HDAC2, MAGEA12, MOV10, HIST1H2BA, MIER3, ANAPC2, MIER1, CDC16, ARID5B, NEK2, ANAPC4, CDC23, CDC27, MIER2, ANAPC5, ANAPC1, FZR1, H2AFX, ANAPC7, ANAPC16


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PSKH1_C16orf87


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PSKH1_C16orf87


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource