	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 28555

FusionGeneSummary for PPT2_TUBB4A

Fusion gene summary

Fusion gene information	Fusion gene name: PPT2_TUBB4A
	Fusion gene ID: 28555
		Hgene	Tgene
	Gene symbol	PPT2	TUBB4A
	Gene ID	9374	10382
	Gene name	palmitoyl-protein thioesterase 2	tubulin beta 4A class IVa
	Synonyms	C6orf8\|G14\|PPT-2	DYT4\|TUBB4\|beta-5
	Cytomap	6p21.32	19p13.3
	Type of gene	protein-coding	protein-coding
	Description	lysosomal thioesterase PPT2S-thioesterase G14VE-statin2palmitoyl-protein hydrolase 2	tubulin beta-4A chaindystonia 4, torsion (autosomal dominant)tubulin beta-4 chaintubulin, beta 4tubulin, beta, 5
	Modification date	20180523	20180523
	UniProtAcc	Q9UMR5	P04350
	Ensembl transtripts involved in fusion gene	ENST00000361568, ENST00000395523, ENST00000324816, ENST00000445576, ENST00000437001, ENST00000375137, ENST00000375143, ENST00000493548, ENST00000412651, ENST00000457509, ENST00000550796, ENST00000547565, ENST00000440533, ENST00000445462, ENST00000486923, ENST00000550232, ENST00000383152, ENST00000399665, ENST00000547646, ENST00000551703, ENST00000399662, ENST00000399660, ENST00000480985, ENST00000467040, ENST00000487203, ENST00000423347, ENST00000440507, ENST00000551222, ENST00000548089, ENST00000424353, ENST00000452304, ENST00000459936, ENST00000549741, ENST00000383301, ENST00000399860, ENST00000546871, ENST00000399859, ENST00000399856, ENST00000414356, ENST00000452562, ENST00000552922, ENST00000549544, ENST00000420778, ENST00000427556, ENST00000483049, ENST00000547891, ENST00000525601, ENST00000547508, ENST00000422988, ENST00000547309, ENST00000552076, ENST00000465052, ENST00000438385, ENST00000456497, ENST00000547558,	ENST00000264071, ENST00000540257, ENST00000601152, ENST00000598006, ENST00000596926,
Fusion gene scores	* DoF score	4 X 4 X 2=32	8 X 8 X 1=64
	# samples	4	8
	** MAII score	log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(8/64*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: PPT2 [Title/Abstract] AND TUBB4A [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			BF933096	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3UTR	ENST00000361568	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000361568	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000361568	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000361568	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000361568	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000395523	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000395523	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000395523	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000395523	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000395523	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000324816	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000324816	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000324816	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000324816	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000324816	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000445576	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000445576	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445576	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445576	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445576	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000437001	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000437001	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000437001	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000437001	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000437001	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000375137	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000375137	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375137	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375137	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375137	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000375143	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000375143	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375143	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375143	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000375143	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000493548	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000493548	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000493548	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000493548	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000493548	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000412651	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000412651	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000412651	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000412651	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000412651	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000457509	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000457509	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000457509	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000457509	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000457509	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000550796	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000550796	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550796	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550796	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550796	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547565	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547565	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547565	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547565	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547565	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000440533	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000440533	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440533	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440533	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440533	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000445462	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000445462	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445462	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445462	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000445462	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000486923	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000486923	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000486923	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000486923	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000486923	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000550232	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000550232	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550232	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550232	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000550232	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000383152	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000383152	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383152	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383152	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383152	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399665	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399665	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399665	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399665	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399665	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547646	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547646	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547646	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547646	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547646	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000551703	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000551703	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551703	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551703	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551703	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399662	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399662	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399662	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399662	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399662	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399660	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399660	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399660	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399660	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399660	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000480985	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000480985	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000480985	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000480985	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000480985	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000467040	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000467040	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000467040	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000467040	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000467040	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000487203	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000487203	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000487203	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000487203	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000487203	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000423347	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000423347	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000423347	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000423347	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000423347	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000440507	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000440507	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440507	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440507	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000440507	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000551222	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000551222	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551222	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551222	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000551222	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000548089	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000548089	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000548089	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000548089	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000548089	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000424353	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000424353	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000424353	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000424353	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000424353	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000452304	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000452304	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452304	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452304	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452304	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000459936	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000459936	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000459936	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000459936	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000459936	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000549741	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000549741	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549741	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549741	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549741	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000383301	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000383301	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383301	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383301	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000383301	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399860	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399860	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399860	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399860	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399860	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000546871	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000546871	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000546871	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000546871	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000546871	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399859	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399859	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399859	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399859	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399859	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399856	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000399856	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399856	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399856	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000399856	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000414356	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000414356	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000414356	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000414356	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000414356	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000452562	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000452562	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452562	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452562	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000452562	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000552922	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000552922	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552922	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552922	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552922	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000549544	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000549544	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549544	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549544	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000549544	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000420778	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000420778	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000420778	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000420778	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000420778	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000427556	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000427556	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000427556	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000427556	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000427556	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000483049	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000483049	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000483049	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000483049	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000483049	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547891	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547891	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547891	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547891	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547891	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000525601	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000525601	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000525601	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000525601	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000525601	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547508	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547508	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547508	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547508	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547508	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000422988	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000422988	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000422988	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000422988	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000422988	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547309	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547309	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547309	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547309	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547309	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000552076	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000552076	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552076	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552076	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000552076	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000465052	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000465052	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000465052	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000465052	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000465052	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000438385	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000438385	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000438385	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000438385	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000438385	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000456497	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000456497	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000456497	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000456497	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000456497	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547558	ENST00000264071	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-3UTR	ENST00000547558	ENST00000540257	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547558	ENST00000601152	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547558	ENST00000598006	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+
intron-intron	ENST00000547558	ENST00000596926	PPT2	chr6	3397973	+	TUBB4A	chr19	6495065	+

Top

FusionProtFeatures for PPT2_TUBB4A

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
PPT2 Q9UMR5	TUBB4A P04350
	Tubulin is the major constituent of microtubules. Itbinds two moles of GTP, one at an exchangeable site on the betachain and one at a non-exchangeable site on the alpha chain.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Top

FusionGeneSequence for PPT2_TUBB4A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for PPT2_TUBB4A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

RelatedDrugs for PPT2_TUBB4A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Tgene	TUBB4A	P04350	DB11638	Artenimol	Tubulin beta-4A chain	small molecule	approved\|investigational

Top

RelatedDiseases for PPT2_TUBB4A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	TUBB4A	C1851943	DYSTONIA 4, TORSION, AUTOSOMAL DOMINANT (disorder)	1	ORPHANET;UNIPROT
Tgene	TUBB4A	C2676244	Leukodystrophy, Hypomyelinating, 6	1	ORPHANET;UNIPROT

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 28555

FusionGeneSummary for PPT2_TUBB4A

FusionProtFeatures for PPT2_TUBB4A

FusionGeneSequence for PPT2_TUBB4A

FusionGenePPI for PPT2_TUBB4A

RelatedDrugs for PPT2_TUBB4A

RelatedDiseases for PPT2_TUBB4A