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Fusion gene ID: 27909 |
FusionGeneSummary for POLB_ASH2L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: POLB_ASH2L | Fusion gene ID: 27909 | Hgene | Tgene | Gene symbol | POLB | ASH2L | Gene ID | 11232 | 9070 |
| Gene name | DNA polymerase gamma 2, accessory subunit | ASH2 like, histone lysine methyltransferase complex subunit | |
| Synonyms | HP55|MTPOLB|PEOA4|POLB|POLG-BETA|POLGB | ASH2|ASH2L1|ASH2L2|Bre2 | |
| Cytomap | 17q23.3 | 8p11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA polymerase subunit gamma-2, mitochondrialDNA polymerase gamma accessory 55 kDa subunitmitochondrial DNA polymerase subunit gamma-2mitochondrial DNA polymerase, accessory subunitp55polymerase (DNA directed), gamma 2, accessory subunitpolymerase ( | set1/Ash2 histone methyltransferase complex subunit ASH2ASH2-like proteinash2 (absent, small, or homeotic)-like | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P06746 | Q9UBL3 | |
| Ensembl transtripts involved in fusion gene | ENST00000265421, ENST00000538005, ENST00000530566, ENST00000521492, | ENST00000343823, ENST00000250635, ENST00000545394, ENST00000428278, ENST00000521652, ENST00000524263, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 6 X 5 X 5=150 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/150*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: POLB [Title/Abstract] AND ASH2L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Transcription factor involved fusion gene, inframe and retained DNA-binding domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ASH2L | GO:0006974 | cellular response to DNA damage stimulus | 17500065 |
| Tgene | ASH2L | GO:0043627 | response to estrogen | 16603732 |
| Tgene | ASH2L | GO:0051568 | histone H3-K4 methylation | 17355966|19556245 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-WR-A838-01A | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000265421 | ENST00000343823 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000265421 | ENST00000250635 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000265421 | ENST00000545394 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000265421 | ENST00000428278 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000265421 | ENST00000521652 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| 5CDS-intron | ENST00000265421 | ENST00000524263 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000538005 | ENST00000343823 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000538005 | ENST00000250635 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000538005 | ENST00000545394 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000538005 | ENST00000428278 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000538005 | ENST00000521652 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| 5CDS-intron | ENST00000538005 | ENST00000524263 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-3CDS | ENST00000530566 | ENST00000343823 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-3CDS | ENST00000530566 | ENST00000250635 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-3CDS | ENST00000530566 | ENST00000545394 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-3CDS | ENST00000530566 | ENST00000428278 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-3CDS | ENST00000530566 | ENST00000521652 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| intron-intron | ENST00000530566 | ENST00000524263 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000521492 | ENST00000343823 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000521492 | ENST00000250635 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000521492 | ENST00000545394 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000521492 | ENST00000428278 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| In-frame | ENST00000521492 | ENST00000521652 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
| 5CDS-intron | ENST00000521492 | ENST00000524263 | POLB | chr8 | 42227506 | + | ASH2L | chr8 | 37976788 | + |
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FusionProtFeatures for POLB_ASH2L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| POLB | ASH2L |
| Repair polymerase that plays a key role in base-excisionrepair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activitythat removes the 5' sugar phosphate and also acts as a DNApolymerase that adds one nucleotide to the 3' end of the arisingsingle-nucleotide gap. Conducts 'gap-filling' DNA synthesis in astepwise distributive fashion rather than in a processive fashionas for other DNA polymerases. {ECO:0000269|PubMed:11805079,ECO:0000269|PubMed:21362556, ECO:0000269|PubMed:9207062,ECO:0000269|PubMed:9572863}. | Component of the Set1/Ash2 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' ofhistone H3, but not if the neighboring 'Lys-9' residue is alreadymethylated. As part of the MLL1/MLL complex it is involved inmethylation and dimethylation at 'Lys-4' of histone H3. Mayfunction as a transcriptional regulator. May play a role inhematopoiesis. {ECO:0000269|PubMed:12670868,ECO:0000269|PubMed:19556245}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | POLB | chr8:42227506 | chr8:37976788 | ENST00000265421 | + | 13 | 14 | 183_192 | 304 | 336 | Region | Note=DNA binding |
| Tgene | >ASH2L | chr8:42227506 | chr8:37976788 | ENST00000250635 | + | 7 | 15 | 360_583 | 190 | 502 | Domain | B30.2/SPRY |
| Tgene | >ASH2L | chr8:42227506 | chr8:37976788 | ENST00000343823 | + | 7 | 16 | 360_583 | 284 | 629 | Domain | B30.2/SPRY |
| Tgene | >ASH2L | chr8:42227506 | chr8:37976788 | ENST00000428278 | + | 7 | 16 | 360_583 | 190 | 535 | Domain | B30.2/SPRY |
| Tgene | >ASH2L | chr8:42227506 | chr8:37976788 | ENST00000521652 | + | 7 | 15 | 360_583 | 190 | 502 | Domain | B30.2/SPRY |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000250635 | + | 7 | 15 | 67_177 | 190 | 502 | Region | Note=DNA-binding |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000343823 | + | 7 | 16 | 67_177 | 284 | 629 | Region | Note=DNA-binding |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000428278 | + | 7 | 16 | 67_177 | 190 | 535 | Region | Note=DNA-binding |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000521652 | + | 7 | 15 | 67_177 | 190 | 502 | Region | Note=DNA-binding |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000250635 | + | 7 | 15 | 117_150 | 190 | 502 | Zinc finger | Note=C4-type |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000250635 | + | 7 | 15 | 1_66 | 190 | 502 | Zinc finger | Note=PHD-type%3B atypical |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000343823 | + | 7 | 16 | 117_150 | 284 | 629 | Zinc finger | Note=C4-type |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000343823 | + | 7 | 16 | 1_66 | 284 | 629 | Zinc finger | Note=PHD-type%3B atypical |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000428278 | + | 7 | 16 | 117_150 | 190 | 535 | Zinc finger | Note=C4-type |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000428278 | + | 7 | 16 | 1_66 | 190 | 535 | Zinc finger | Note=PHD-type%3B atypical |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000521652 | + | 7 | 15 | 117_150 | 190 | 502 | Zinc finger | Note=C4-type |
| Tgene | ASH2L | chr8:42227506 | chr8:37976788 | ENST00000521652 | + | 7 | 15 | 1_66 | 190 | 502 | Zinc finger | Note=PHD-type%3B atypical |
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FusionGeneSequence for POLB_ASH2L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_649aa MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDG YRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEM PPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYF EEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADV >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_616aa MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDG YRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEM PPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYF >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_649aa MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDG YRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEM PPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYF EEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADV >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_649aa MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDG YRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEM PPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYF EEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADV >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_616aa MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVL YFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDG YRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEM PPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYF >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_495aa MLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSK NDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKA RSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGE KGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPE DTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKY >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_462aa MLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSK NDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKA RSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGE KGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPE DTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETE >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_495aa MLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSK NDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKA RSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGE KGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPE DTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKY >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_495aa MLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSK NDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKA RSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGE KGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPE DTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKY >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_462aa MLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSK NDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKA RSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGE KGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPE DTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETE >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_368aa MRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPH APDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS QPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEK SLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGR >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_335aa MRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPH APDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS QPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEK >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_368aa MRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPH APDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS QPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEK SLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGR >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_368aa MRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPH APDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS QPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEK SLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGR >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_335aa MRAHALEKGFTINEYTIRPLGVTGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPH APDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWS QPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_1947nt ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGC CAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAG AAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAG GATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAA ACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATT CCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTC TATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCC TTGGGAGTCACTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACC ACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGC TATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGA GACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACT GTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATG CCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGG CGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATT AATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTT GAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAA GGTGTGGCTTACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCA TGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTC >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_1848nt ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGC CAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAG AAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAG GATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAA ACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATT CCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTC TATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCC TTGGGAGTCACTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACC ACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGC TATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGA GACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACT GTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATG CCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGG CGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATT AATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTT GAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAG TATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCAC >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_1947nt ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGC CAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAG AAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAG GATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAA ACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATT CCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTC TATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCC TTGGGAGTCACTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACC ACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGC TATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGA GACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACT GTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATG CCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGG CGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATT AATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTT GAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAA GGTGTGGCTTACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCA TGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTC >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_1947nt ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGC CAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAG AAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAG GATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAA ACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATT CCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTC TATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCC TTGGGAGTCACTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACC ACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGC TATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGA GACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACT GTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATG CCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGG CGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATT AATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTT GAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAA GGTGTGGCTTACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCA TGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTC >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_1848nt ATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGC CAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAG AAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAG GATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAA ACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATT CCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGT TTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAG CTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTC TATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCC TTGGGAGTCACTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACC ACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGC TATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGA GACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACT GTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATG CCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGG CGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATT AATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTT GAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAG TATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCAC >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_1485nt ATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGT GCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTT GTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAA AATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGG AGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACT GGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATT CTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAG AAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAG GGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGAC TTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTAC AAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTAT CCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTG >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_1386nt ATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGT GCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTT GTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAA AATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGG AGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACT GGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATT CTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAG AAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAG GGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGAC TTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAG GATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAA >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_1485nt ATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGT GCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTT GTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAA AATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGG AGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACT GGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATT CTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAG AAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAG GGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGAC TTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTAC AAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTAT CCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTG >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_1485nt ATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGT GCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTT GTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAA AATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGG AGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACT GGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATT CTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAG AAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAG GGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGAC TTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTAC AAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTAT CCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTG >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_1386nt ATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGT GCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTT GTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAA AATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGG AGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACT GGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCC CGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATT CTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGA GCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAG AAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACC GCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAG GGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAA GACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGAC TTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAG GATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAA >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_1104nt ATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATTGCAGCAGGAAGC AGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCT GCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCAC GCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTT TTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGG GCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCC CAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCC ATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCA TTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAG AGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATTTTTGAGGGGGTT TACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTAC CGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGGAGG >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_1005nt ATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATTGCAGCAGGAAGC AGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCT GCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCAC GCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTT TTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGG GCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCC CAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCC ATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCA TTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAG AGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATG AGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGGAGGCGCAGTCCC >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_1104nt ATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATTGCAGCAGGAAGC AGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCT GCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCAC GCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTT TTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGG GCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCC CAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCC ATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCA TTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAG AGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATTTTTGAGGGGGTT TACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTAC CGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGGAGG >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_1104nt ATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATTGCAGCAGGAAGC AGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCT GCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCAC GCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTT TTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGG GCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCC CAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCC ATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCA TTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAG AGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATTTTTGAGGGGGTT TACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTAC CGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGGAGG >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_1005nt ATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATTGCAGCAGGAAGC AGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCT GCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCAC GCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTT TTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGG GCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCC CAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCC ATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCA TTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAG AGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACTTACCGCCCTATG AGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGGAGGCGCAGTCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_3011nt AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAA GTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAAC GGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCC ACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTG GAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGA GTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAG ATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAG AGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAG GTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGG TTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTG GGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCA CTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGG CCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATA TTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACA GAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAG AGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATA CCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAA AGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTG AAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAG ACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTT ACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGT ATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACG TGGAGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACT GGGGGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTG GGTAGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCG CTGACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTA AGGAGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGA AATGGTAACCTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGT TTTGTTCATTTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCA GCTTTAACAAAATGAGAAACTTCCCAAATAAAACTTGTTTTGAAGTTTATGTGACACTTTGCTTCCCTTCAGATTGGGTGCCTCTTGGTG ACAGTGTTCAGAAATGTAAGCAGCACGAGGAAGGGAGCTGGCACTGGGAGGAAGAGCCGGGTTTCTGAGTTGTGTTTTGGCTGCTTTCCT ATTGCTCCCATTCTTGCCAATCAGCCACCCCCTTTCCTGTGAAAATCTGCCACCTTGAGGAGAGGAACAAGAGTTTAAAAGGGCTAATGA >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_2654nt AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAA GTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAAC GGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCC ACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTG GAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGA GTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAG ATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAG AGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAG GTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGG TTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTG GGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCA CTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGG CCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATA TTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACA GAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAG AGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATA CCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAA AGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTG AAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAG ACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGA AGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAG AAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTT GTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACT GCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCA GGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAA TAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAAC CTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCAT TTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACA >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_2569nt AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAA GTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAAC GGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCC ACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTG GAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGA GTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAG ATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAG AGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAG GTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGG TTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTG GGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCA CTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGG CCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATA TTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACA GAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAG AGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATA CCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAA AGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTG AAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAG ACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTT ACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGT ATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACG TGGAGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACT GGGGGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTG GGTAGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCG CTGACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTA AGGAGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGA >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_2749nt AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAA GTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAAC GGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCC ACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTG GAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGA GTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAG ATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAG AGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAG GTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGG TTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTG GGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCA CTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGG CCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATA TTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACA GAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAG AGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATA CCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAA AGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTG AAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAG ACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTT ACAAAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGT ATCCTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACG TGGAGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACT GGGGGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTG GGTAGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCG CTGACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTA AGGAGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGA AATGGTAACCTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGT TTTGTTCATTTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCA >In-frame_POLB_ENST00000265421_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_2650nt AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAA GTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAAC GGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCC ACAAGTACAATGCTTACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTG GAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGA GTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAG ATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAG AGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAG GTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGG TTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTG GGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCA CTGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGG CCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATA TTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACA GAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAG AGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATA CCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAA AGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTG AAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAG ACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGA AGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAG AAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTT GTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACT GCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCA GGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAA TAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAAC CTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCAT TTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACA >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_2730nt ATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTC CCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCG ACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGATCTCAGAAAA AATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAA ATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCC AGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAG TTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAA AAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATT TTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATT TTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAG GATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAA GTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGT TTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGC GGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGG ATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATA ATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCT GTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTT TGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAA ATGAGAAACTTCCCAAATAAAACTTGTTTTGAAGTTTATGTGACACTTTGCTTCCCTTCAGATTGGGTGCCTCTTGGTGACAGTGTTCAG AAATGTAAGCAGCACGAGGAAGGGAGCTGGCACTGGGAGGAAGAGCCGGGTTTCTGAGTTGTGTTTTGGCTGCTTTCCTATTGCTCCCAT TCTTGCCAATCAGCCACCCCCTTTCCTGTGAAAATCTGCCACCTTGAGGAGAGGAACAAGAGTTTAAAAGGGCTAATGATCTCCCTCCCG >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_2373nt ATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTC CCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCG ACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGATCTCAGAAAA AATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAA ATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCC AGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAG TTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAA AAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATT TTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACT TACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGG AGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGTTTTTGTTTT TGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGCGGGAGACTG CCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGGATTGCATAA GCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATAATATTGTCC GAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCTGTTTCTGAG AACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTTTGAAATACA CTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAAATGAGAAAC >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_2288nt ATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTC CCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCG ACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGATCTCAGAAAA AATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAA ATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCC AGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAG TTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAA AAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATT TTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATT TTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAG GATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAA GTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGT TTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGC GGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGG ATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATA ATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCT >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_2468nt ATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTC CCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCG ACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGATCTCAGAAAA AATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAA ATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCC AGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAG TTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAA AAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATT TTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACAAAGATATT TTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAG GATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAA GTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGT TTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGC GGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGG ATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATA ATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCT GTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTT TGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAA >In-frame_POLB_ENST00000538005_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_2369nt ATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTACCTCCTTCAAGCTGGGAGAGGGCTCTAGTC CCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACTCTCAACGGGGGAATCACCG ACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGATCTCAGAAAA AATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAA ATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCC AGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAG TTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAA AAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATT TTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGGATCTCACT TACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAGTGGATGGG AGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGTTTTTGTTTT TGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGCGGGAGACTG CCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGGATTGCATAA GCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATAATATTGTCC GAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCTGTTTCTGAG AACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTTTGAAATACA CTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAAATGAGAAAC >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000343823_chr8_37976788_+_2468nt TCATCGTTTCTTCCACGTTGCTCTCTTCTGTTTATTTTGATGTCTGTGTTTCGTGTTCAGGGTTTTCTTTGATTAGTTTCTTGCTTAGAA TCACACAAAGACCAAATCCTCATAATGAGAATCCTTATTTGCAGTTTTGTGTAGTTCTCTAATTATCGTGAAGTGTAATAGAAAGGTAGG GATAGTGTATTGCTCACAGAAGCTGCTAAGTTAAAAGTGCTCAGAATTCTAGAGCTGCTAACATTAAAAACAAAAATGGCCTTGTGTTTT ACTTGATTAAAATTAAGCCTTAAGTTTAGAACATCTTTAAACTTGGTTTAAAATGTTCATTTTAGGGTGTTTGCCAGCTTCCCAGTAAAA ATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGA GTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTG GGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCC GGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTC TAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAG CCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGA AGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCG CTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGG GAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAG ACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACT TTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACA AAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATC CTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGG AGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGG GGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGT AGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTG ACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGG AGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAAT GGTAACCTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTT GTTCATTTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCT TTAACAAAATGAGAAACTTCCCAAATAAAACTTGTTTTGAAGTTTATGTGACACTTTGCTTCCCTTCAGATTGGGTGCCTCTTGGTGACA GTGTTCAGAAATGTAAGCAGCACGAGGAAGGGAGCTGGCACTGGGAGGAAGAGCCGGGTTTCTGAGTTGTGTTTTGGCTGCTTTCCTATT GCTCCCATTCTTGCCAATCAGCCACCCCCTTTCCTGTGAAAATCTGCCACCTTGAGGAGAGGAACAAGAGTTTAAAAGGGCTAATGATCT >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000250635_chr8_37976788_+_2111nt TCATCGTTTCTTCCACGTTGCTCTCTTCTGTTTATTTTGATGTCTGTGTTTCGTGTTCAGGGTTTTCTTTGATTAGTTTCTTGCTTAGAA TCACACAAAGACCAAATCCTCATAATGAGAATCCTTATTTGCAGTTTTGTGTAGTTCTCTAATTATCGTGAAGTGTAATAGAAAGGTAGG GATAGTGTATTGCTCACAGAAGCTGCTAAGTTAAAAGTGCTCAGAATTCTAGAGCTGCTAACATTAAAAACAAAAATGGCCTTGTGTTTT ACTTGATTAAAATTAAGCCTTAAGTTTAGAACATCTTTAAACTTGGTTTAAAATGTTCATTTTAGGGTGTTTGCCAGCTTCCCAGTAAAA ATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGA GTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTG GGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCC GGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTC TAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAG CCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGA AGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCG CTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGG GAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAG ACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACT TTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGG ATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAG TGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGTT TTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGCG GGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGGA TTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATAA TATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCTG TTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTTT GAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAAA >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000545394_chr8_37976788_+_2026nt TCATCGTTTCTTCCACGTTGCTCTCTTCTGTTTATTTTGATGTCTGTGTTTCGTGTTCAGGGTTTTCTTTGATTAGTTTCTTGCTTAGAA TCACACAAAGACCAAATCCTCATAATGAGAATCCTTATTTGCAGTTTTGTGTAGTTCTCTAATTATCGTGAAGTGTAATAGAAAGGTAGG GATAGTGTATTGCTCACAGAAGCTGCTAAGTTAAAAGTGCTCAGAATTCTAGAGCTGCTAACATTAAAAACAAAAATGGCCTTGTGTTTT ACTTGATTAAAATTAAGCCTTAAGTTTAGAACATCTTTAAACTTGGTTTAAAATGTTCATTTTAGGGTGTTTGCCAGCTTCCCAGTAAAA ATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGA GTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTG GGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCC GGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTC TAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAG CCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGA AGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCG CTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGG GAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAG ACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACT TTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACA AAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATC CTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGG AGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGG GGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGT AGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTG ACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGG AGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAAT >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000428278_chr8_37976788_+_2206nt TCATCGTTTCTTCCACGTTGCTCTCTTCTGTTTATTTTGATGTCTGTGTTTCGTGTTCAGGGTTTTCTTTGATTAGTTTCTTGCTTAGAA TCACACAAAGACCAAATCCTCATAATGAGAATCCTTATTTGCAGTTTTGTGTAGTTCTCTAATTATCGTGAAGTGTAATAGAAAGGTAGG GATAGTGTATTGCTCACAGAAGCTGCTAAGTTAAAAGTGCTCAGAATTCTAGAGCTGCTAACATTAAAAACAAAAATGGCCTTGTGTTTT ACTTGATTAAAATTAAGCCTTAAGTTTAGAACATCTTTAAACTTGGTTTAAAATGTTCATTTTAGGGTGTTTGCCAGCTTCCCAGTAAAA ATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGA GTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTG GGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCC GGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTC TAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAG CCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGA AGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCG CTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGG GAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAG ACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACT TTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGATAATATTTTATAAAAATGGTGTCAATCAAGGTGTGGCTTACA AAGATATTTTTGAGGGGGTTTACTTCCCAGCCATCTCACTGTACAAGAGCTGCACGGTTTCCATTAACTTTGGACCATGCTTCAAGTATC CTCCGAAGGATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGG AGACAGAAGTGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGG GGTTTTGTTTTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGT AGGACTGCGGGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTG ACTCCAGGATTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGG AGTGAATAATATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAAT GGTAACCTGTTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTT GTTCATTTTGAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCT >In-frame_POLB_ENST00000521492_chr8_42227506_+_ASH2L_ENST00000521652_chr8_37976788_+_2107nt TCATCGTTTCTTCCACGTTGCTCTCTTCTGTTTATTTTGATGTCTGTGTTTCGTGTTCAGGGTTTTCTTTGATTAGTTTCTTGCTTAGAA TCACACAAAGACCAAATCCTCATAATGAGAATCCTTATTTGCAGTTTTGTGTAGTTCTCTAATTATCGTGAAGTGTAATAGAAAGGTAGG GATAGTGTATTGCTCACAGAAGCTGCTAAGTTAAAAGTGCTCAGAATTCTAGAGCTGCTAACATTAAAAACAAAAATGGCCTTGTGTTTT ACTTGATTAAAATTAAGCCTTAAGTTTAGAACATCTTTAAACTTGGTTTAAAATGTTCATTTTAGGGTGTTTGCCAGCTTCCCAGTAAAA ATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGA GTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTG GGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCC GGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTC TAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAG CCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGA AGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCG CTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGG GAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAG ACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACT TTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGTTTCCATTAACTTTGGACCATGCTTCAAGTATCCTCCGAAGG ATCTCACTTACCGCCCTATGAGTGACATGGGCTGGGGCGCCGTGGTAGAGCACACCCTGGCTGACGTCTTGTATCACGTGGAGACAGAAG TGGATGGGAGGCGCAGTCCCCCATGGGAACCCTGACCAGGTCCCTCTTTTCTGTCAAGGACTTTCTGGGAATAATACTGGGGGTTTTGTT TTTGTTTTTGAACTGTCTCAAATGTTCTCCCAAAGATGCTAAAAACACAGCCTCTCCTTTTAGCAAGTTAAAAGGCTGGGTAGGACTGCG GGAGACTGCCTGCCTTTCACCATTTTCTCCCCACTTCCAGTGACTGCTCTTATTTTGTGTACCATAAGCCAACAACCGCTGACTCCAGGA TTGCATAAGCCCCCTGTGAAATCGGTGCTGTACTGCATACCCTGCCAGCTGTGACTTGTTATCCTACTATATTTTCTAAGGAGTGAATAA TATTGTCCGAGTAACTAACTTATTTAAAAGACATTTCCTTCTGTGGGCATTGACTGTATCCCACCTGTTTTCCAAGGAAATGGTAACCTG TTTCTGAGAACACCTGAAATCAATGGCTATACATTCCAAACCAATCTAAACGCTATTTCCTTTTGGTGTGGGTTTGGTTTTGTTCATTTT GAAATACACTTTTGAACACTGAGATCCGTAAAACTACTAGATCTCTGGAAGTGTAATTGTGAAAGAAACTTGCTTGCAGCTTTAACAAAA |
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FusionGenePPI for POLB_ASH2L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| POLB | TAF1D, XRCC1, NEIL1, TLE1, KAT7, PNKP, WRN, NCAPG, PCNA, PARP1, STUB1, HUWE1, UNG, SRPK2, TPP2, APEX1, EP300, XPC, SUPT16H, LIG3, TDP1, PARP2, SSRP1, APLF, HIST1H2AG, HIST2H2AB, BCKDHB, CETN2, APTX, BCKDHA, HSD17B7, HIST1H2BG, XRCC3, EMC2, MMGT1 | ASH2L | DPY30, KMT2A, ASH2L, MEN1, RBBP5, WDR5, HCFC1, HCFC2, KMT2C, HIST3H3, UNC119, CXXC1, SETD1A, WDR82P1, KDM6A, PHF8, MYB, CHD8, CTNNB1, ZNF335, CCAR2, C11orf30, NCOA6, ZSCAN1, HIST1H3A, SRRM1, PAX7, MEF2D, SETD1B, PAXIP1, KMT2D, USF1, PAGR1, KMT2B, E2F1, E2F4, PRMT1, WDR82, PSMC5, PYGO2, CDC73, ESR1, KDM4B, BARD1, BRCA1, PPP1CC, KDM6B, SMAD9, WWP1, SENP3, PPARG, PKN1, EP300, TP53, MICU2, XPO1, FOXQ1, DNMT3L, CHD7, KMT2E, CCDC69, EPB41L5, FOXA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for POLB_ASH2L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | POLB | P06746 | DB01592 | Iron | DNA polymerase beta | small molecule | approved |
| Hgene | POLB | P06746 | DB00987 | Cytarabine | DNA polymerase beta | small molecule | approved|investigational |
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RelatedDiseases for POLB_ASH2L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | POLB | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Hgene | POLB | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| Hgene | POLB | C0023434 | Chronic Lymphocytic Leukemia | 1 | CTD_human |
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