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Fusion gene ID: 2748 |
FusionGeneSummary for ARMC1_PEX19 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARMC1_PEX19 | Fusion gene ID: 2748 | Hgene | Tgene | Gene symbol | ARMC1 | PEX19 | Gene ID | 55156 | 5824 |
| Gene name | armadillo repeat containing 1 | peroxisomal biogenesis factor 19 | |
| Synonyms | Arcp | D1S2223E|HK33|PBD12A|PMP1|PMPI|PXF|PXMP1 | |
| Cytomap | 8q13.1 | 1q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | armadillo repeat-containing protein 1 | peroxisomal biogenesis factor 1933 kDa housekeeping proteinhousekeeping gene, 33kDperoxin-19peroxisomal farnesylated protein | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q9NVT9 | P40855 | |
| Ensembl transtripts involved in fusion gene | ENST00000276569, ENST00000458464, ENST00000523384, | ENST00000368072, ENST00000440949, ENST00000532508, | |
| Fusion gene scores | * DoF score | 4 X 2 X 2=16 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/16*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ARMC1 [Title/Abstract] AND PEX19 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PEX19 | GO:0006625 | protein targeting to peroxisome | 16344115|16763195 |
| Tgene | PEX19 | GO:0045046 | protein import into peroxisome membrane | 11402059|14709540 |
| Tgene | PEX19 | GO:0050821 | protein stabilization | 14709540|16344115 |
| Tgene | PEX19 | GO:0061077 | chaperone-mediated protein folding | 14709540 |
| Tgene | PEX19 | GO:0072321 | chaperone-mediated protein transport | 11402059|14709540 |
| Tgene | PEX19 | GO:1900131 | negative regulation of lipid binding | 19715730 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A7-A4SE-01A | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000276569 | ENST00000368072 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| In-frame | ENST00000276569 | ENST00000440949 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| 5CDS-5UTR | ENST00000276569 | ENST00000532508 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-3CDS | ENST00000458464 | ENST00000368072 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-3CDS | ENST00000458464 | ENST00000440949 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-5UTR | ENST00000458464 | ENST00000532508 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-3CDS | ENST00000523384 | ENST00000368072 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-3CDS | ENST00000523384 | ENST00000440949 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
| intron-5UTR | ENST00000523384 | ENST00000532508 | ARMC1 | chr8 | 66525479 | - | PEX19 | chr1 | 160249635 | - |
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FusionProtFeatures for ARMC1_PEX19 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARMC1 | PEX19 |
| Necessary for early peroxisomal biogenesis. Acts both asa cytosolic chaperone and as an import receptor for peroxisomalmembrane proteins (PMPs). Binds and stabilizes newly synthesizedPMPs in the cytoplasm by interacting with their hydrophobicmembrane-spanning domains, and targets them to the peroxisomemembrane by binding to the integral membrane protein PEX3.Excludes CDKN2A from the nucleus and prevents its interaction withMDM2, which results in active degradation of TP53.{ECO:0000269|PubMed:10051604, ECO:0000269|PubMed:10704444,ECO:0000269|PubMed:11259404, ECO:0000269|PubMed:11883941,ECO:0000269|PubMed:14709540, ECO:0000269|PubMed:15007061}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARMC1 | chr8:66525479 | chr1:160249635 | ENST00000276569 | - | 4 | 7 | 39_81 | 155 | 283 | Repeat | Note=ARM |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PEX19 | chr8:66525479 | chr1:160249635 | ENST00000368072 | - | 5 | 8 | 2_56 | 257 | 300 | Region | Note=Docking to the peroxisome membrane and binding to PEX3 |
| Tgene | PEX19 | chr8:66525479 | chr1:160249635 | ENST00000368072 | - | 5 | 8 | 2_91 | 257 | 300 | Region | Note=Necessary for PEX19 function on peroxisome biogenesis |
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FusionGeneSequence for ARMC1_PEX19 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000368072_chr1_160249635_-_198aa MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVI QKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTLQDLGHPPKELAGEMPPGLNFDLDA >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000440949_chr1_160249635_-_198aa MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVI QKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTLQDLGHPPKELAGEMPPGLNFDLDA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000368072_chr1_160249635_-_594nt ATGAATTCTTCCACTTCCACCATGAGTGAAGAGCCTGACGCTCTATCGGTAGTTAACCAGTTACGGGATCTAGCAGCAGATCCGTTAAAC AGAAGAGCCATCGTCCAGGATCAGGGATGTCTGCCTGGCCTTATTTTATTTATGGACCATCCCAACCCTCCAGTCGTCCACTCCGCTTTG CTTGCTCTTCGATACTTGGCAGAATGCCGTGCAAACAGAGAAAAGATGAAAGGAGAACTGGGTATGATGTTGAGCTTACAAAATGTTATA CAGAAAACTACAACTCCAGGAGAAACAAAACTTCTGGCCTCTGAAATCTATGACATTCTTCAGTCCTCCAATATGGCAGATGGTGATAGT TTTAATGAGATGAATTCACGTCGAAGGAAAGCTCAATTTTTTCTGGGAACTACAAACAAACGTGCCAAAACAGTGGTTTTGCATATAGAT GGCCTTGATGATACGCTACAAGATTTAGGCCATCCTCCAAAAGAGCTGGCTGGAGAGATGCCTCCTGGCCTCAACTTTGACCTGGATGCC >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000440949_chr1_160249635_-_594nt ATGAATTCTTCCACTTCCACCATGAGTGAAGAGCCTGACGCTCTATCGGTAGTTAACCAGTTACGGGATCTAGCAGCAGATCCGTTAAAC AGAAGAGCCATCGTCCAGGATCAGGGATGTCTGCCTGGCCTTATTTTATTTATGGACCATCCCAACCCTCCAGTCGTCCACTCCGCTTTG CTTGCTCTTCGATACTTGGCAGAATGCCGTGCAAACAGAGAAAAGATGAAAGGAGAACTGGGTATGATGTTGAGCTTACAAAATGTTATA CAGAAAACTACAACTCCAGGAGAAACAAAACTTCTGGCCTCTGAAATCTATGACATTCTTCAGTCCTCCAATATGGCAGATGGTGATAGT TTTAATGAGATGAATTCACGTCGAAGGAAAGCTCAATTTTTTCTGGGAACTACAAACAAACGTGCCAAAACAGTGGTTTTGCATATAGAT GGCCTTGATGATACGCTACAAGATTTAGGCCATCCTCCAAAAGAGCTGGCTGGAGAGATGCCTCCTGGCCTCAACTTTGACCTGGATGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000368072_chr1_160249635_-_3578nt GAGGCGTCAGGTCACCTGGGAAGAGTCTGCAGAGCCTTTGCCCGCCAGCGCCTTCGCTCTTTGGCTCCCTGAGTTAGTCCGGTTGCTTGC GATCGCCGCGGCCGGGGCTGCGAACCGAAGGGCTCGCTCCGCGCCGCCTGGGTCTCTACCTCATCCGTAGGTGTGGCCCTGATGGTGTGG CAGGCTCTGGACTCCTAAAGCTCTGGAGCGAATTTAAGATTTTATTCATGTGCATGGCATAGAAGATGAATTCTTCCACTTCCACCATGA GTGAAGAGCCTGACGCTCTATCGGTAGTTAACCAGTTACGGGATCTAGCAGCAGATCCGTTAAACAGAAGAGCCATCGTCCAGGATCAGG GATGTCTGCCTGGCCTTATTTTATTTATGGACCATCCCAACCCTCCAGTCGTCCACTCCGCTTTGCTTGCTCTTCGATACTTGGCAGAAT GCCGTGCAAACAGAGAAAAGATGAAAGGAGAACTGGGTATGATGTTGAGCTTACAAAATGTTATACAGAAAACTACAACTCCAGGAGAAA CAAAACTTCTGGCCTCTGAAATCTATGACATTCTTCAGTCCTCCAATATGGCAGATGGTGATAGTTTTAATGAGATGAATTCACGTCGAA GGAAAGCTCAATTTTTTCTGGGAACTACAAACAAACGTGCCAAAACAGTGGTTTTGCATATAGATGGCCTTGATGATACGCTACAAGATT TAGGCCATCCTCCAAAAGAGCTGGCTGGAGAGATGCCTCCTGGCCTCAACTTTGACCTGGATGCCCTCAATCTTTCGGGCCCACCAGGTG CCAGTGGTGAACAGTGTCTGATCATGTGAAACACAACACGTTTTCCTCTCTGAGTCCCAGCTATGGGGAACATCTGGAGTCAGCAGAACC ATTGGGACCTGAGGCAGGAGTGTCACCTGCGGGAGAAGTCTGCCCGCTGCCCTCTGTCATCCCATTCAAGATTGTGCCATACCAGCTGAG GTTTTTCCTCTGTCTCTCTAGGAATAGGGTCTGTTTCACAGGCCATTTCTGTGAACCCTACTCCATTGTGGTTTCTGCCACTATCAAAGT TCCAGCTACCTGCAAGGTGAAGGAAGGCATCCCTTTTGGGGCATGCACTTTCTTTCCTTTCTCAAAATAATGTTATATGTGGCCACACTG ATGTTCACCTTTACGTCCAGGGTCTTTGTGCCTTGTCTCTACTCCCTCTCTTGGATCTGGGGAGGAGGGGCAGAGACCTGGGACTCTGTA TTTCTATAGTTCTCCTGGCAGAGCCTTTGAGAATGGGGAGAAACAGCCTGGGCTGGGGCTACAGGTCTGTCACTATGCTCTCTTGCCTTC AGACAGACCATTCTGAATTCTCTAAAGGGAAAGGGCTTTTGCATCTAATCACAATAGAGTTGAAAGAGAGGCCTTAGGATTCTCCTCTCT CTAGGTGCTGAGCCCTCACCTCCCTGTTCCAGGCTGAGAACTCAAATGGTTACCCTGCTTCTTCCTACAATGCTGTGTGATATGGGTGAA CCCAGCCCCTGACCTTCCTCTATCCCCTGCCCATCCTCCCTTTTACCTCCTCTCTTTTTTAAACACCTGTTTATCCCAACCTTTTTGAGC TCAAGCTGTGATAAAGAAGGGCCCATCCTATTTCCCCTCATCTAGTCCATTTACGATTCTCACTGACTCCCCGTCTTCCTGGCAGACACA AATAAACCCAGTGTCAGGTCTAGGAAATTAATGGCTATTCTTCCCCAGATACATTCTGGCTTATTTGAGATACATGATTCTCTTAGAATC CTGTCCCTTGGTTCAGGAAAGTAGCTTGGAAAAGGAGTAGGGGTATAGCTTGGGTCCCTTTTCCTGCAAGGCCCCATGGGGCAGAATATA ATAAATATTCTGAGTGAGGAGTGTGGTCTTTTTCTGATCTTCCTCAGCTTCCGTAAGTTGCAGAGTGAGGTATATTAGGAGACTAGTTCT ACACAATATTGTAATGCTGGGTTCCATCAACACCCACCTTCCACAACTCAGTCTGCACCTCAGTTGGCAAAGGAGACTGGATGGCCATCT TTCCTCATGTTCCCTTGAGTATTTCAATGTAGAAAGCCCTTCAAGTGGTATTATATTTTAACCTTTTACATTATTGTTATTAATGTTAGT AATATATTGTTATGTTTTCTAAATTATTTTTCTTTAAGCTGACGTGGCTTTTTTTCTGTGGCTCCCAGTGGGTCTACGGACCTTGGCTGA CATATGTTGGTAGGTACTCTGGTCAGCTCAGCTGGCTGTCCTGGTTCACTCAGAAGATAAGTCTCTCCAAAGCAAATTCACATGCATTAT GAGTCGCTTTGAGCTTCTGACATGTCACTTGCCCCGAGGTTAAAACTTTTCACCCCTTGAAGACCTTACATGTTTTATGGTATTGGTGAG GAAGGAAATGTTCTCAAGGTCTCAGGCTATTTGGGAAATTCCAACTCCTATACCTTACCAGAGCATGGAAGAGCCCAGATCTGAATGTAA AACGTCTCTGTTCTGCCAGAGATGGAAAAAATACAGGTATACTTGTGATATAGTCATGGGGCTTCAGTGTCACTATTTTCTCCTTAAAGC TCCAGCCAAAAACTGGACAAGGATAGAGAGGAGGAGGGAAGAACAAAAGAGCCCTTCTCTATGAACCTTGTGCCTTCTGTCCTACCAGTT TTCTTTTACAGATTCTCACTTCTGCTAGCCTAGCCAGGGCTTACTCCAGGAATCTAAATAGATGCCCTAGTCCACTTTATCTTTGTTCCC AAGGCACTCATTTTTATTTTGATTTTGATTGAATGTGAGCAGGTTGACCTCAGGTCACACTTTGTTCCAAAAACTTTTGGAATTATTCCA GGACTTGTGGTGGAGTTATGGTACTCTAGGGCAGTCTTTCTCAAACTATGTATGGTAAAGGACCAGGTTTTTTGTTTTCCAGTCCTTCAC TTATCAATATGCATTCCTATTGCCCATGACAGGTATGGAGTTCACACTGTGTGCTGCCGACCCGGCAAGTTTGACAGCACCCAAACTGGC CAGACTGTTCTGTAGGTTAAGTCCATTGATCATGTACTTGGATATCACAGCAACATTGAAATGCTAAAAAGTTTTTAAACACTCTCAATT TCTAATTCACCATGTCACAGACTGGTGAAAAAAAAAAAAAGGTGTTCACTGACCAGCACAAGTCTGCAGATCATCTTTGAGTAGCACTGT TTTGGGGCCCTCGGTCTCTCTGAAGACCCTAGCAGAACTGATACCTACCTGTATCTCTTGTTCTCTCCTATTTGAGTTTCACTTCCAGAG AACTTGTTCTTCAGCAAGAATGTGTCACTAGTAAGGACATCTCTAGCATTTCTCTAGCCTTCCTTTTCTGCTGCTCAAAAATAATCGTTA CAAAGCTTAGGTTTAAGCTGTATATGAAATATTTATGCGACTCTCAAACTTTAAAGGAGTTGCTCCTTTGTTCCAAAATTAAATGTGTTA >In-frame_ARMC1_ENST00000276569_chr8_66525479_-_PEX19_ENST00000440949_chr1_160249635_-_1909nt GAGGCGTCAGGTCACCTGGGAAGAGTCTGCAGAGCCTTTGCCCGCCAGCGCCTTCGCTCTTTGGCTCCCTGAGTTAGTCCGGTTGCTTGC GATCGCCGCGGCCGGGGCTGCGAACCGAAGGGCTCGCTCCGCGCCGCCTGGGTCTCTACCTCATCCGTAGGTGTGGCCCTGATGGTGTGG CAGGCTCTGGACTCCTAAAGCTCTGGAGCGAATTTAAGATTTTATTCATGTGCATGGCATAGAAGATGAATTCTTCCACTTCCACCATGA GTGAAGAGCCTGACGCTCTATCGGTAGTTAACCAGTTACGGGATCTAGCAGCAGATCCGTTAAACAGAAGAGCCATCGTCCAGGATCAGG GATGTCTGCCTGGCCTTATTTTATTTATGGACCATCCCAACCCTCCAGTCGTCCACTCCGCTTTGCTTGCTCTTCGATACTTGGCAGAAT GCCGTGCAAACAGAGAAAAGATGAAAGGAGAACTGGGTATGATGTTGAGCTTACAAAATGTTATACAGAAAACTACAACTCCAGGAGAAA CAAAACTTCTGGCCTCTGAAATCTATGACATTCTTCAGTCCTCCAATATGGCAGATGGTGATAGTTTTAATGAGATGAATTCACGTCGAA GGAAAGCTCAATTTTTTCTGGGAACTACAAACAAACGTGCCAAAACAGTGGTTTTGCATATAGATGGCCTTGATGATACGCTACAAGATT TAGGCCATCCTCCAAAAGAGCTGGCTGGAGAGATGCCTCCTGGCCTCAACTTTGACCTGGATGCCCTCAATCTTTCGGGCCCACCAGGTG CCAGTGGTGAACAGTGTCTGATCATGTGAAACACAACACGTTTTCCTCTCTGAGTCCCAGCTATGGGGAACATCTGGAGTCAGCAGAACC ATTGGGACCTGAGGCAGGAGTGTCACCTGCGGGAGAAGTCTGCCCGCTGCCCTCTGTCATCCCATTCAAGATTGTGCCATACCAGCTGAG GTTTTTCCTCTGTCTCTCTAGGAATAGGGTCTGTTTCACAGGCCATTTCTGTGAACCCTACTCCATTGTGGTTTCTGCCACTATCAAAGT TCCAGCTACCTGCAAGGTGAAGGAAGGCATCCCTTTTGGGGCATGCACTTTCTTTCCTTTCTCAAAATAATGTTATATGTGGCCACACTG ATGTTCACCTTTACGTCCAGGGTCTTTGTGCCTTGTCTCTACTCCCTCTCTTGGATCTGGGGAGGAGGGGCAGAGACCTGGGACTCTGTA TTTCTATAGTTCTCCTGGCAGAGCCTTTGAGAATGGGGAGAAACAGCCTGGGCTGGGGCTACAGGTCTGTCACTATGCTCTCTTGCCTTC AGACAGACCATTCTGAATTCTCTAAAGGGAAAGGGCTTTTGCATCTAATCACAATAGAGTTGAAAGAGAGGCCTTAGGATTCTCCTCTCT CTAGGTGCTGAGCCCTCACCTCCCTGTTCCAGGCTGAGAACTCAAATGGTTACCCTGCTTCTTCCTACAATGCTGTGTGATATGGGTGAA CCCAGCCCCTGACCTTCCTCTATCCCCTGCCCATCCTCCCTTTTACCTCCTCTCTTTTTTAAACACCTGTTTATCCCAACCTTTTTGAGC TCAAGCTGTGATAAAGAAGGGCCCATCCTATTTCCCCTCATCTAGTCCATTTACGATTCTCACTGACTCCCCGTCTTCCTGGCAGACACA AATAAACCCAGTGTCAGGTCTAGGAAATTAATGGCTATTCTTCCCCAGATACATTCTGGCTTATTTGAGATACATGATTCTCTTAGAATC CTGTCCCTTGGTTCAGGAAAGTAGCTTGGAAAAGGAGTAGGGGTATAGCTTGGGTCCCTTTTCCTGCAAGGCCCCATGGGGCAGAATATA |
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FusionGenePPI for ARMC1_PEX19 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ARMC1 | CALM1, ELAVL1, APP, EPS8, MTFR1L, CRMP1, DPYSL3, DPYSL2, STXBP1, ATP4A, DPYSL5, CAMK2A, CAMK2B, DNAJC11, GPM6B, HIST1H2BL, VSNL1, NCAM1, EPB41L1, GNAO1, GNG2, GPM6A, SNCB, SYN2, SYN1, RAB3A, CNTN1, MAP2, CAMKV, NCALD, STX1B, SYT1, DCTN2, FUS, GALE, SEC23A, UFD1L, DNAAF5, GARS, HNRNPDL, HSPBP1, HSPA8, MAPT, UBC | PEX19 | PEX16, PEX3, ABCD1, ABCD3, ABCD2, PEX10, PEX12, PEX13, PEX11B, PEX14, SLC25A17, ELAVL1, NUDCD2, NUBP2, DSTN, HSPB1, PEX11A, PEX26, SMAD2, PXMP2, EGFR, PXMP4, PMP22, SRPK1, MFSD5, F11R, KIFAP3, GSKIP, STK3, TMEM54, CDC25A, IRF3, EIF1B, OIP5, VCP, PTPLAD1, PPIB, IL23A, FKBP7, UBAC2, FAF2, CD33, COMTD1, SLC27A4, ASPM, MYO1D, MYO5C, MYO5B, MYO5A, CHSY1, HSD17B11, TMX2, FAM174A, MGAT2, ATP13A2, HADHB, FAR2, FAM20B, IQGAP3, EXOG, GLCE, CMSS1, MANEAL, EXD2, EXT1, RHOT1, HINT3, CENPP, TMTC4, TMEM246, CYC1, SOAT1, POMGNT1, MOSPD2, GALNT2, PNKD, HS2ST1, MUL1, FBXO30, LETMD1, PTOV1, QPCTL, EGLN1, C3orf33, GLB1L2, SCCPDH, UXS1, RDH12, TTF2, SEPN1, ABHD12, MBTPS1, SELT, MARC2, UQCR10, UQCRH, GALNT16, B3GALT6, MRPL20, NAT14, PLD6, HIGD2A, TUSC3, CHST7, CA14, IQCF1, POLE2, PSMA5, PSMB1, PSMB4, POLE, PSMD6, XPO1, PTPN4, TPTE2, EPHA1, SIGLECL1, C12orf49, PTPRN |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ARMC1_PEX19 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ARMC1_PEX19 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PEX19 | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | PEX19 | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Tgene | PEX19 | C0043459 | Zellweger Syndrome | 1 | CTD_human;ORPHANET |
| Tgene | PEX19 | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| Tgene | PEX19 | C1832200 | Peroxisome biogenesis disorders | 1 | CTD_human |
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