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Fusion gene ID: 2745 |
FusionGeneSummary for ARL8B_USP4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARL8B_USP4 | Fusion gene ID: 2745 | Hgene | Tgene | Gene symbol | ARL8B | USP4 | Gene ID | 55207 | 7375 |
| Gene name | ADP ribosylation factor like GTPase 8B | ubiquitin specific peptidase 4 | |
| Synonyms | ARL10C|Gie1 | UNP|Unph | |
| Cytomap | 3p26.1 | 3p21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP-ribosylation factor-like protein 8BADP-ribosylation factor-like 10CADP-ribosylation factor-like 8BADP-ribosylation factor-like protein 10Cnovel small G protein indispensable for equal chromosome segregation 1 | ubiquitin carboxyl-terminal hydrolase 4deubiquitinating enzyme 4ubiquitin carboxyl-terminal esterase 4ubiquitin specific peptidase 4 (proto-oncogene)ubiquitin specific protease 4 (proto-oncogene)ubiquitin thioesterase 4ubiquitin thiolesterase 4ubiq | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q9NVJ2 | Q13107 | |
| Ensembl transtripts involved in fusion gene | ENST00000256496, ENST00000419534, ENST00000468010, | ENST00000351842, ENST00000265560, ENST00000488520, ENST00000416417, ENST00000415188, | |
| Fusion gene scores | * DoF score | 4 X 2 X 5=40 | 4 X 4 X 3=48 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/40*10)=0.584962500721156 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/48*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARL8B [Title/Abstract] AND USP4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | USP4 | GO:0016579 | protein deubiquitination | 16316627|16339847|16472766 |
| Tgene | USP4 | GO:0031647 | regulation of protein stability | 16472766 |
| Tgene | USP4 | GO:0034394 | protein localization to cell surface | 16339847 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-D5-6534-01A | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000256496 | ENST00000351842 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| In-frame | ENST00000256496 | ENST00000265560 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-5UTR | ENST00000256496 | ENST00000488520 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-intron | ENST00000256496 | ENST00000416417 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-intron | ENST00000256496 | ENST00000415188 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| In-frame | ENST00000419534 | ENST00000351842 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| In-frame | ENST00000419534 | ENST00000265560 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-5UTR | ENST00000419534 | ENST00000488520 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-intron | ENST00000419534 | ENST00000416417 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| 5CDS-intron | ENST00000419534 | ENST00000415188 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| intron-3CDS | ENST00000468010 | ENST00000351842 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| intron-3CDS | ENST00000468010 | ENST00000265560 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| intron-5UTR | ENST00000468010 | ENST00000488520 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| intron-intron | ENST00000468010 | ENST00000416417 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
| intron-intron | ENST00000468010 | ENST00000415188 | ARL8B | chr3 | 5164273 | + | USP4 | chr3 | 49339975 | - |
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FusionProtFeatures for ARL8B_USP4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARL8B | USP4 |
| May play a role in lysosome motility (PubMed:16537643,PubMed:25898167). May play a role in chromosome segregation(PubMed:15331635). {ECO:0000269|PubMed:15331635,ECO:0000269|PubMed:16537643, ECO:0000269|PubMed:25898167}. | Hydrolase that deubiquitinates target proteins such asthe receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination ofADORA2A increases the amount of functional receptor at the cellsurface. May regulate mRNA splicing through deubiquitination ofthe U4 spliceosomal protein PRPF3. This may prevent itsrecognition by the U5 component PRPF8 thereby destabilizinginteractions within the U4/U6.U5 snRNP. May also play a role inthe regulation of quality control in the ER.{ECO:0000269|PubMed:16316627, ECO:0000269|PubMed:16339847,ECO:0000269|PubMed:16472766, ECO:0000269|PubMed:20595234,ECO:0000269|PubMed:7784062}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARL8B | chr3:5164273 | chr3:49339975 | ENST00000256496 | + | 1 | 7 | 1_19 | 41 | 187 | Intramembrane | Note=Note%3DMediates targeting to membranes |
| Hgene | ARL8B | chr3:5164273 | chr3:49339975 | ENST00000256496 | + | 1 | 7 | 29_35 | 41 | 187 | Nucleotide binding | Note=GTP |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 483_571 | 376 | 964 | Domain | Note=Ubiquitin-like 2 |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 483_571 | 329 | 917 | Domain | Note=Ubiquitin-like 2 |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 11_122 | -4 | 314 | Domain | DUSP |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 142_226 | -4 | 314 | Domain | Note=Ubiquitin-like 1 |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 302_923 | -4 | 314 | Domain | Note=USP |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 483_571 | -4 | 314 | Domain | Note=Ubiquitin-like 2 |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 767_772 | 376 | 964 | Motif | Nuclear localization signal |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 767_772 | 329 | 917 | Motif | Nuclear localization signal |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 133_141 | -4 | 314 | Motif | Nuclear export signal |
| Tgene | >USP4 | chr3:5164273 | chr3:49339975 | ENST00000416417 | - | 0 | 7 | 767_772 | -4 | 314 | Motif | Nuclear localization signal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ARL8B | chr3:5164273 | chr3:49339975 | ENST00000256496 | + | 1 | 7 | 130_133 | 41 | 187 | Nucleotide binding | Note=GTP |
| Hgene | >ARL8B | chr3:5164273 | chr3:49339975 | ENST00000256496 | + | 1 | 7 | 71_75 | 41 | 187 | Nucleotide binding | GTP |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 11_122 | 376 | 964 | Domain | DUSP |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 142_226 | 376 | 964 | Domain | Note=Ubiquitin-like 1 |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 302_923 | 376 | 964 | Domain | Note=USP |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 11_122 | 329 | 917 | Domain | DUSP |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 142_226 | 329 | 917 | Domain | Note=Ubiquitin-like 1 |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 302_923 | 329 | 917 | Domain | Note=USP |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000265560 | - | 8 | 22 | 133_141 | 376 | 964 | Motif | Nuclear export signal |
| Tgene | USP4 | chr3:5164273 | chr3:49339975 | ENST00000351842 | - | 7 | 21 | 133_141 | 329 | 917 | Motif | Nuclear export signal |
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FusionGeneSequence for ARL8B_USP4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_629aa MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIATQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANG RPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAV SDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPL LLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQK KIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELF TTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYG >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_629aa MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIATQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANG RPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAV SDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPL LLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQK KIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELF TTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYG >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_629aa MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIATQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANG RPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAV SDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPL LLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQK KIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELF TTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYG >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_629aa MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIATQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANG RPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAV SDLCEALSRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVTLPVYFRERKSRPSSTSSASALYGQPL LLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEFGSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQK KIKGQPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAYEKHVSMLQPQKKKKTTVALRDCIELF TTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_1887nt ATGCTGGCGCTCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTAC TCGGGCAAGACCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAG GAGCTGCTGGCCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGG CGGCCAGATGCGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTC AAATCTACTTTGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAA GATCGAGTTATGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTG TCCGACCTGTGCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAA ATTTTCCAAATGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCG GAATGTGTCACGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTA TTGCTTTCTGTCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTA CCTGATGAGTTTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAG CATCAGGAAGAAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAG AAGATCAAAGGCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCT GATGGAAAACTACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAA TCTGAGGCCTACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTC ACCACCATGGAGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGG TCCTTGCCCAAGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCA ATCAGAGGGCTGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGA GCCATGGGGGTTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCC TCTGAGGATCAGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGT >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_1887nt ATGCTGGCGCTCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTAC TCGGGCAAGACCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAG GAGCTGCTGGCCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGG CGGCCAGATGCGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTC AAATCTACTTTGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAA GATCGAGTTATGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTG TCCGACCTGTGCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAA ATTTTCCAAATGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCG GAATGTGTCACGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTA TTGCTTTCTGTCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTA CCTGATGAGTTTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAG CATCAGGAAGAAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAG AAGATCAAAGGCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCT GATGGAAAACTACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAA TCTGAGGCCTACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTC ACCACCATGGAGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGG TCCTTGCCCAAGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCA ATCAGAGGGCTGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGA GCCATGGGGGTTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCC TCTGAGGATCAGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGT >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_1887nt ATGCTGGCGCTCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTAC TCGGGCAAGACCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAG GAGCTGCTGGCCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGG CGGCCAGATGCGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTC AAATCTACTTTGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAA GATCGAGTTATGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTG TCCGACCTGTGCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAA ATTTTCCAAATGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCG GAATGTGTCACGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTA TTGCTTTCTGTCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTA CCTGATGAGTTTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAG CATCAGGAAGAAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAG AAGATCAAAGGCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCT GATGGAAAACTACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAA TCTGAGGCCTACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTC ACCACCATGGAGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGG TCCTTGCCCAAGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCA ATCAGAGGGCTGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGA GCCATGGGGGTTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCC TCTGAGGATCAGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGT >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_1887nt ATGCTGGCGCTCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTAC TCGGGCAAGACCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAG GAGCTGCTGGCCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGG CGGCCAGATGCGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTC AAATCTACTTTGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAA GATCGAGTTATGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTG TCCGACCTGTGCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAA ATTTTCCAAATGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCG GAATGTGTCACGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTA TTGCTTTCTGTCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTA CCTGATGAGTTTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAG CATCAGGAAGAAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAG AAGATCAAAGGCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCT GATGGAAAACTACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAA TCTGAGGCCTACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTC ACCACCATGGAGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGG TCCTTGCCCAAGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCA ATCAGAGGGCTGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGA GCCATGGGGGTTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCC TCTGAGGATCAGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_2595nt GGATTGGCCGCGCCGCTCTTGCCGTGGGTGCCGACGGCGGCGCCGGGACGGGCGTGGGGGGTAGGGCGAGTCATATGATCCGCTCGGCTT CCTGGGTCTGGCTGCTGCCGCCCGCCGGTGTCCGCCCGTGTCGCGCCGGGGCACCAAGGAGCCGTTGGAGGGTCCGGGCGGAGGCCCGCT CGTGTGGAAGTCGTCGACGCCGCCGCTCGTCCGTCCTCCCGTCCGTTCTCGCTCCCGGCCGCCATCATGCTGGCGCTCATCTCCCGCCTG CTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTACTCGGGCAAGACCACCTTCGTCAAT GTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAGGAGCTGCTGGCCTTTCTTCTAGAT GGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGGCGGCCAGATGCGGTGGTGGCAAAG GAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTCAAATCTACTTTGGTTTGCCCAGAA TGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAAGATCGAGTTATGGAGGTTTTCCTG GTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTGTCCGACCTGTGCGAGGCTCTCTCC AGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAAATTTTCCAAATGGATGAAGGTTTA AACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCGGAATGTGTCACGCTTCCAGTCTAC TTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTATTGCTTTCTGTCCCCAAGCACAAG TTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTACCTGATGAGTTTGGCAGCTCACCC TTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAGCATCAGGAAGAAGGCAAAGAGCAG CTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAGAAGATCAAAGGCCAGCCCTGCCCA AAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCTGATGGAAAACTACTTAAACTCAAC TCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAATCTGAGGCCTACGAGAAGCATGTG AGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTCACCACCATGGAGACCCTTGGGGAG CATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGGTCCTTGCCCAAGATCCTGGTGGTC CACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCAATCAGAGGGCTGAACATGTCCGAG TTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGAGCCATGGGGGTTGGCCACTACACT GCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCCTCTGAGGATCAGATAGTGACTAAA GCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGTTCTGGTTCCTCTGATGGAGGGACA CGACCAAGCAGCTCTCAGCAGGGCTTTGGGGATGATGAGGCTTGCAGCATGGACACCAACTAATGCTGACTCCACGATCCTGCCACCCTG TAGCGCCAGTGTAATCCCCCAGGAGAACATCTTTGACACTCTGCAGACTGCTAGTGTTCTGTCTAAAAACCAGACAAGGAAATACCCTTC TTTTATGAGCAGAAGGAAACAAAAAAAAAAAAAGAAGACCGTTTACCTAGAAGAAGCTATGTCAAGAGGCTGAATTATTTTTATTTTTAA ACAGGTGGTGAGAAATTTCTGTGAAACCTGTGAAGCTGAAAAGGGGGTGGGATGGGGGTACTCAATGGAGTATGTCTGATGGATCCCGAA GAATGGAGAGGAACACAGGCGCTGAGTATGGAGCAGCCTGGAGACCCACCCCACCTGCAGGGCTGCCCTGAGCGCCTGGATTTCTGGTTC >In-frame_ARL8B_ENST00000256496_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_2320nt GGATTGGCCGCGCCGCTCTTGCCGTGGGTGCCGACGGCGGCGCCGGGACGGGCGTGGGGGGTAGGGCGAGTCATATGATCCGCTCGGCTT CCTGGGTCTGGCTGCTGCCGCCCGCCGGTGTCCGCCCGTGTCGCGCCGGGGCACCAAGGAGCCGTTGGAGGGTCCGGGCGGAGGCCCGCT CGTGTGGAAGTCGTCGACGCCGCCGCTCGTCCGTCCTCCCGTCCGTTCTCGCTCCCGGCCGCCATCATGCTGGCGCTCATCTCCCGCCTG CTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTACTCGGGCAAGACCACCTTCGTCAAT GTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAGGAGCTGCTGGCCTTTCTTCTAGAT GGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGGCGGCCAGATGCGGTGGTGGCAAAG GAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTCAAATCTACTTTGGTTTGCCCAGAA TGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAAGATCGAGTTATGGAGGTTTTCCTG GTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTGTCCGACCTGTGCGAGGCTCTCTCC AGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAAATTTTCCAAATGGATGAAGGTTTA AACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCGGAATGTGTCACGCTTCCAGTCTAC TTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTATTGCTTTCTGTCCCCAAGCACAAG TTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTACCTGATGAGTTTGGCAGCTCACCC TTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAGCATCAGGAAGAAGGCAAAGAGCAG CTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAGAAGATCAAAGGCCAGCCCTGCCCA AAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCTGATGGAAAACTACTTAAACTCAAC TCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAATCTGAGGCCTACGAGAAGCATGTG AGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTCACCACCATGGAGACCCTTGGGGAG CATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGGTCCTTGCCCAAGATCCTGGTGGTC CACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCAATCAGAGGGCTGAACATGTCCGAG TTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGAGCCATGGGGGTTGGCCACTACACT GCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCCTCTGAGGATCAGATAGTGACTAAA GCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGTTCTGGTTCCTCTGATGGAGGGACA CGACCAAGCAGCTCTCAGCAGGGCTTTGGGGATGATGAGGCTTGCAGCATGGACACCAACTAATGCTGACTCCACGATCCTGCCACCCTG TAGCGCCAGTGTAATCCCCCAGGAGAACATCTTTGACACTCTGCAGACTGCTAGTGTTCTGTCTAAAAACCAGACAAGGAAATACCCTTC >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000351842_chr3_49339975_-_2519nt GATCCGCTCGGCTTCCTGGGTCTGGCTGCTGCCGCCCGCCGGTGTCCGCCCGTGTCGCGCCGGGGCACCAAGGAGCCGTTGGAGGGTCCG GGCGGAGGCCCGCTCGTGTGGAAGTCGTCGACGCCGCCGCTCGTCCGTCCTCCCGTCCGTTCTCGCTCCCGGCCGCCATCATGCTGGCGC TCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTACTCGGGCAAGA CCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAGGAGCTGCTGG CCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGGCGGCCAGATG CGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTCAAATCTACTT TGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAAGATCGAGTTA TGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTGTCCGACCTGT GCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAAATTTTCCAAA TGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCGGAATGTGTCA CGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTATTGCTTTCTG TCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTACCTGATGAGT TTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAGCATCAGGAAG AAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAGAAGATCAAAG GCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCTGATGGAAAAC TACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAATCTGAGGCCT ACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTCACCACCATGG AGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGGTCCTTGCCCA AGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCAATCAGAGGGC TGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGAGCCATGGGGG TTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCCTCTGAGGATC AGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGTTCTGGTTCCT CTGATGGAGGGACACGACCAAGCAGCTCTCAGCAGGGCTTTGGGGATGATGAGGCTTGCAGCATGGACACCAACTAATGCTGACTCCACG ATCCTGCCACCCTGTAGCGCCAGTGTAATCCCCCAGGAGAACATCTTTGACACTCTGCAGACTGCTAGTGTTCTGTCTAAAAACCAGACA AGGAAATACCCTTCTTTTATGAGCAGAAGGAAACAAAAAAAAAAAAAGAAGACCGTTTACCTAGAAGAAGCTATGTCAAGAGGCTGAATT ATTTTTATTTTTAAACAGGTGGTGAGAAATTTCTGTGAAACCTGTGAAGCTGAAAAGGGGGTGGGATGGGGGTACTCAATGGAGTATGTC TGATGGATCCCGAAGAATGGAGAGGAACACAGGCGCTGAGTATGGAGCAGCCTGGAGACCCACCCCACCTGCAGGGCTGCCCTGAGCGCC >In-frame_ARL8B_ENST00000419534_chr3_5164273_+_USP4_ENST00000265560_chr3_49339975_-_2244nt GATCCGCTCGGCTTCCTGGGTCTGGCTGCTGCCGCCCGCCGGTGTCCGCCCGTGTCGCGCCGGGGCACCAAGGAGCCGTTGGAGGGTCCG GGCGGAGGCCCGCTCGTGTGGAAGTCGTCGACGCCGCCGCTCGTCCGTCCTCCCGTCCGTTCTCGCTCCCGGCCGCCATCATGCTGGCGC TCATCTCCCGCCTGCTGGACTGGTTCCGTTCGCTCTTCTGGAAGGAAGAGATGGAGCTGACGCTCGTGGGGCTGCAGTACTCGGGCAAGA CCACCTTCGTCAATGTCATCGCGACTCAAGTAGGACGTTTTGCTCCTCAATTTTCTGGCTACCAGCAACAAGATTCTCAGGAGCTGCTGG CCTTTCTTCTAGATGGATTGCATGAAGATCTGAACCGGGTAAAGAAAAAGCCCTACTTGGAGCTGAAGGATGCCAATGGGCGGCCAGATG CGGTGGTGGCAAAGGAAGCCTGGGAGAATCACAGGTTGAGGAATGATTCTGTGATTGTGGATACTTTCCATGGCCTCTTCAAATCTACTT TGGTTTGCCCAGAATGTGCTAAGGTTTCTGTGACCTTTGACCCATTTTGCTATCTAACGCTGCCACTGCCCTTGAAGAAAGATCGAGTTA TGGAGGTTTTCCTGGTTCCTGCTGACCCTCACTGCAGACCTACTCAGTACCGTGTGACTGTGCCGCTGATGGGGGCTGTGTCCGACCTGT GCGAGGCTCTCTCCAGGCTGTCTGGCATTGCTGCAGAAAATATGGTGGTCGCAGATGTGTATAATCACCGATTCCACAAAATTTTCCAAA TGGATGAAGGTTTAAACCACATCATGCCTCGGGATGACATTTTCGTGTACGAGGTCTGCAGCACTTCCGTGGATGGCTCGGAATGTGTCA CGCTTCCAGTCTACTTCAGGGAGAGGAAGTCCAGGCCATCAAGCACTTCCTCCGCATCAGCGCTATATGGGCAGCCACTATTGCTTTCTG TCCCCAAGCACAAGTTAACCCTTGAGTCTTTGTACCAGGCTGTTTGTGATCGTATCAGCCGCTATGTGAAACAGCCTTTACCTGATGAGT TTGGCAGCTCACCCTTGGAGCCAGGGGCCTGCAATGGCTCCAGGAACAGCTGTGAAGGAGAAGATGAGGAAGAAATGGAGCATCAGGAAG AAGGCAAAGAGCAGCTTTCAGAAACAGAAGGCAGTGGGGAAGATGAGCCAGGAAATGACCCCAGTGAGACCACCCAAAAGAAGATCAAAG GCCAGCCCTGCCCAAAAAGGCTTTTTACCTTCAGTCTTGTGAACTCCTATGGAACAGCTGACATAAATTCACTTGCAGCTGATGGAAAAC TACTTAAACTCAACTCTCGATCTACACTGGCCATGGATTGGGACAGTGAAACTCGGAGACTTTACTATGATGAGCAAGAATCTGAGGCCT ACGAGAAGCATGTGAGCATGTTGCAGCCTCAGAAGAAGAAGAAGACCACAGTGGCCCTGAGAGACTGCATCGAGCTCTTCACCACCATGG AGACCCTTGGGGAGCATGACCCCTGGTACTGTCCCAACTGTAAGAAGCATCAACAGGCCACAAAAAAGTTTGACCTATGGTCCTTGCCCA AGATCCTGGTGGTCCACCTCAAACGTTTCTCCTACAACAGATACTGGAGGGATAAGCTCGACACAGTCGTAGAATTCCCAATCAGAGGGC TGAACATGTCCGAGTTTGTCTGTAACCTGTCAGCAAGGCCTTATGTGTACGACCTCATTGCCGTGTCCAATCATTATGGAGCCATGGGGG TTGGCCACTACACTGCATATGCGAAGAACAAACTGAATGGTAAATGGTATTACTTTGATGATAGCAACGTGTCCCTGGCCTCTGAGGATC AGATAGTGACTAAAGCAGCTTATGTGCTATTTTACCAACGTCGAGATGATGAATTTTATAAGACACCTTCACTTAGCAGTTCTGGTTCCT CTGATGGAGGGACACGACCAAGCAGCTCTCAGCAGGGCTTTGGGGATGATGAGGCTTGCAGCATGGACACCAACTAATGCTGACTCCACG ATCCTGCCACCCTGTAGCGCCAGTGTAATCCCCCAGGAGAACATCTTTGACACTCTGCAGACTGCTAGTGTTCTGTCTAAAAACCAGACA |
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FusionGenePPI for ARL8B_USP4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ARL8B | ATP5J2, TUBB, ELAVL1, ATP6V1B1, APP, AMH, BTN3A3, SRPRB, DGUOK, DNAAF2, SDF4, VPS4A, SGOL2, FAM63B, ETFA, RAB2A, RAB7A, SSR4, FOXS1, DUSP19, DUSP9, GRPR, PMEL, LAMP3, OAZ3, PCDHGB1, TBC1D22B, MAS1, CPLX3, RAB29, RAET1E, ALPI, IL17RC, HCCS, GBA | USP4 | TP53BP2, RB1, RBL1, RBL2, TRIM21, ADSL, USP11, USP1, PRPF4, PRPF3, AKAP7, EIF4E2, PPIH, LSM6, LSM4, PRPF31, LSM7, LSM8, DCP1A, MEPCE, LSM2, TUT1, EDC3, USP32, DCP1B, SART3, IGKV2D-29, UBC, USP4, TRAF2, TRAF6, TK1, CDKN1A, SMN1, RCC1, ANXA7, HUWE1, PDK1, MAP3K7, IKBKB, RIPK1, TNFRSF1A, TGFBR1, AKT1, YWHAH, SFN, USP15, USP19, CUL4B, NLK, LGALS1, PSMD11, FAM96B, PSAP, ATP1B3, LAMA5, NPC2, PSMA6, ATP1B1, PLOD1, PPIA, ASS1, PGM1, PSMC5, TRIM63, TRIM55, TRIM54, USP21, USP28, BRAP, DDX58, PTEN, PLA2G2A, PRPF19, PCNA, CT55, OBFC1, TCEAL1, ELMO1, NTRK1, TCF7L2, RORC, HDAC2, RAD50, MRE11A, RBBP8, PTP4A3, CTNNB1, RNPS1, TCP10L, CABP1, JUNB, RNF19B, RAB30, FAM196A, MAP3K6, BSPRY, LGALS7, TRMT1, ENSA, RIPPLY2, ATP6V0D1, EXOC1, C6orf141, SLX1A, FAM46A, SRP9, IRF8, SMAD4 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ARL8B_USP4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ARL8B_USP4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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