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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 2651

FusionGeneSummary for ARID2_ZNF641

check button Fusion gene summary
Fusion gene informationFusion gene name: ARID2_ZNF641
Fusion gene ID: 2651
HgeneTgene
Gene symbol

ARID2

ZNF641

Gene ID

196528

121274

Gene nameAT-rich interaction domain 2zinc finger protein 641
SynonymsBAF200|CSS6|p200-
Cytomap

12q12

12q13.11

Type of geneprotein-codingprotein-coding
DescriptionAT-rich interactive domain-containing protein 2ARID domain-containing protein 2AT rich interactive domain 2 (ARID, RFX-like)BRG1-associated factor 200zinc finger protein with activation potentialzipzap/p200zinc finger protein 641
Modification date2018051920180523
UniProtAcc

Q68CP9

Q96N77

Ensembl transtripts involved in fusion geneENST00000334344, ENST00000422737, 
ENST00000479608, ENST00000444670, 
ENST00000457135, 
ENST00000301042, 
ENST00000544117, ENST00000448928, 
ENST00000547026, 
Fusion gene scores* DoF score8 X 5 X 7=2801 X 1 X 1=1
# samples 81
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: ARID2 [Title/Abstract] AND ZNF641 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARID2

GO:0006337

nucleosome disassembly

8895581

HgeneARID2

GO:0008285

negative regulation of cell proliferation

26169693

HgeneARID2

GO:0030336

negative regulation of cell migration

26169693


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-AR-A1AV-01AARID2chr12

46125097

+ZNF641chr12

48741898

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000334344ENST00000301042ARID2chr12

46125097

+ZNF641chr12

48741898

-
In-frameENST00000334344ENST00000544117ARID2chr12

46125097

+ZNF641chr12

48741898

-
5CDS-5UTRENST00000334344ENST00000448928ARID2chr12

46125097

+ZNF641chr12

48741898

-
5CDS-5UTRENST00000334344ENST00000547026ARID2chr12

46125097

+ZNF641chr12

48741898

-
5UTR-3CDSENST00000422737ENST00000301042ARID2chr12

46125097

+ZNF641chr12

48741898

-
5UTR-3CDSENST00000422737ENST00000544117ARID2chr12

46125097

+ZNF641chr12

48741898

-
5UTR-5UTRENST00000422737ENST00000448928ARID2chr12

46125097

+ZNF641chr12

48741898

-
5UTR-5UTRENST00000422737ENST00000547026ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000479608ENST00000301042ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000479608ENST00000544117ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000479608ENST00000448928ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000479608ENST00000547026ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000444670ENST00000301042ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000444670ENST00000544117ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000444670ENST00000448928ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000444670ENST00000547026ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000457135ENST00000301042ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-3CDSENST00000457135ENST00000544117ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000457135ENST00000448928ARID2chr12

46125097

+ZNF641chr12

48741898

-
intron-5UTRENST00000457135ENST00000547026ARID2chr12

46125097

+ZNF641chr12

48741898

-

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FusionProtFeatures for ARID2_ZNF641


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARID2

Q68CP9

ZNF641

Q96N77

Transcriptional activator. Activates transcriptionalactivities of SRE and AP-1. {ECO:0000269|PubMed:16343441}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17109_1815439DomainKRAB
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05109_181-9416DomainKRAB
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06109_1815439DomainKRAB
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06109_181-9425DomainKRAB
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17171_2655439RegionNote=Transactivation
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05171_265-9416RegionNote=Transactivation
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06171_2655439RegionNote=Transactivation
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06171_265-9425RegionNote=Transactivation
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17264_2865439Zinc fingerC2H2-type 1
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17292_3145439Zinc fingerC2H2-type 2
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17320_3425439Zinc fingerC2H2-type 3
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17372_3945439Zinc fingerC2H2-type 4
TgeneZNF641chr12:46125097chr12:48741898ENST00000301042-17400_4225439Zinc fingerC2H2-type 5
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05264_286-9416Zinc fingerC2H2-type 1
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05292_314-9416Zinc fingerC2H2-type 2
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05320_342-9416Zinc fingerC2H2-type 3
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05372_394-9416Zinc fingerC2H2-type 4
TgeneZNF641chr12:46125097chr12:48741898ENST00000448928-05400_422-9416Zinc fingerC2H2-type 5
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06264_2865439Zinc fingerC2H2-type 1
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06292_3145439Zinc fingerC2H2-type 2
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06320_3425439Zinc fingerC2H2-type 3
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06372_3945439Zinc fingerC2H2-type 4
TgeneZNF641chr12:46125097chr12:48741898ENST00000544117-06400_4225439Zinc fingerC2H2-type 5
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06264_286-9425Zinc fingerC2H2-type 1
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06292_314-9425Zinc fingerC2H2-type 2
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06320_342-9425Zinc fingerC2H2-type 3
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06372_394-9425Zinc fingerC2H2-type 4
TgeneZNF641chr12:46125097chr12:48741898ENST00000547026-06400_422-9425Zinc fingerC2H2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARID2chr12:46125097chr12:48741898ENST00000334344+321793_1128941836Compositional biasNote=Gln-rich
HgeneARID2chr12:46125097chr12:48741898ENST00000334344+321524_603941836DNA bindingRFX-type winged-helix
HgeneARID2chr12:46125097chr12:48741898ENST00000334344+32113_105941836DomainARID
HgeneARID2chr12:46125097chr12:48741898ENST00000334344+321313_317941836MotifNote=LXXLL
HgeneARID2chr12:46125097chr12:48741898ENST00000334344+3211632_1657941836Zinc fingerNote=C2H2-type


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FusionGeneSequence for ARID2_ZNF641


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_528aa
MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALK
QYYLRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNT
GDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDI
LRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGK
QFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRK

>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_528aa
MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALK
QYYLRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNT
GDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDI
LRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGK
QFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRK


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_1584nt
ATGGCAAACTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGA
GGGTCGCCTTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTC
GCGAAGGTTTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAA
CAGTATTACTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAAT
GTACAGCTGGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTG
TGCTGTGACCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACT
GGAGACTGGGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAG
GAGTGGCGGAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTT
CCAATTCCCAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATT
CTGAGGGTCACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTG
TCTGAAGATACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCT
TTTCTTCAGGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAA
CAGTTTGTATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTT
GGGCGAAGACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGC
AACTCCCATCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAA
CGGCAGCGTGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGG
CTGACCCACACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACC

>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_1584nt
ATGGCAAACTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGA
GGGTCGCCTTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTC
GCGAAGGTTTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAA
CAGTATTACTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAAT
GTACAGCTGGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTG
TGCTGTGACCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACT
GGAGACTGGGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAG
GAGTGGCGGAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTT
CCAATTCCCAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATT
CTGAGGGTCACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTG
TCTGAAGATACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCT
TTTCTTCAGGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAA
CAGTTTGTATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTT
GGGCGAAGACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGC
AACTCCCATCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAA
CGGCAGCGTGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGG
CTGACCCACACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACC


* Fusion transcript sequences (Full-length transcript).
>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_4721nt
GCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCACCGCCGGCCCATGACTGAGCCCCGCCGCCGCCGGCCGAGGAATGGGCTCCG
GGCTCTGGTAGGAAGCGCTGGGAGCGGGGGGCGCTTTTAAAACACCGATCTGGGTTTTTTAAAAACCTCCTTTGAAAAAATAATGGCAAA
CTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGAGGGTCGCC
TTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTCGCGAAGGT
TTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAACAGTATTA
CTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAATGTACAGCT
GGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTGTGCTGTGA
CCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACTGGAGACTG
GGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAGGAGTGGCG
GAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTTCCAATTCC
CAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATTCTGAGGGT
CACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTGTCTGAAGA
TACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCTTTTCTTCA
GGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAACAGTTTGT
ATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTTGGGCGAAG
ACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGCAACTCCCA
TCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAACGGCAGCG
TGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGGCTGACCCA
CACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACCCACCAGGG
ACAAAGTCCCCGGAACAGCTGGGACAGAGGAACATCTGTCTTTTGAAATCTGTTTCCACTACAGCTATGGTCAAGTCTATCAGCCGGTGC
TACCAGGAGTCACTGCCAGGGCTGCCGTTCTCCTGAACCCCAGTGGCCAGAATCATAAGCCCTGACCCCATCCCTAGAAAGATGAGGTCC
CAGCAATGGCCAGAGCATTTCTCACCAGTTCTGTGAGATAGCACATAAAAATAGAGTTCTTTGGGCAAAACTTTTGGGAAGCAATGCATC
CTACATGGGCTGATATTCAGCCTGAGCTGTTCTCAAGAGGAGAGTGGTACTGGCAGTTTATGGCTGAAATCCATTCTGATTGGTTGGAGT
CTATGCTATACCAGTTGTTAAACATTTTGAGTATCACTCTTGCATACTGTTACTATTATATTTTCTCTATATATAGACAGAAAGGCCATT
TTAGAATATTAAAGGCTCTGAAAATTTCTGCAGTAGACCCAACTGAAGGTTCTATTAAGGCAGTGTTTCCTAAATGTATTTGACCTCAGT
ATCCTTTCTATTTACATCCCACAGAACTGGTGACTATGAAACACTCTGGTGAACACTGGGTTAGAGAGTAACAAGGAAACAAGAGATAGT
GATCAGGCATCCAGAGCCCCCTTTTTTATCCATATGAAAGCCAGGGGGGCCAGACCTTGTTCATGTGTGGGTCTGTCTTCCTTATGCCAA
TCAGCAGTATATACATCACCTCTCACCCTCACCTGCTGAAAAAATAACCTTTTTACCCATTATTCCTACTCCCTTCATCCTGCACATACA
TATATCCAGCTGAGAGATCACACTACAAGGCTAAGAGATGATCTAATACCCCCAAATAGCCCTGGCCCACACAGAAAAACAGAAAAACAA
AAAAAACTTTATCCCCTTGAACAGTCCCCTCTCTCCTCTTGACTGTCTTTATGTGTCTGTGTATTTGTGTGCAGGGTCTTTGAAGACAGC
ATGCTATGTGCAAACTGTACAAGCTAGGTTTTCTAGGGGCTGTGTTCTGGGGATGAGGGTAGTGGGGATTATATGGGGTTTTTTCTTTGT
TTCAAGACAGGAAGCAGTCTGGTTAAGGGAGAACTAGTGGAAAGGGTTAAATGACAGGTTAAGTTGAGTACAAAGCTTTCCCAGTACTGC
TGAGATTAAGACAATTGTGGATGTGTATGTCTAGGTTTGAATCTCTGGGCTGCAGATTGCTTTTGCCCTGGCAGAGAAAGAGGAGTCTTT
GGGGAGGTGAGCTGTTTCTTGTTGATTTCAGGCAAGAGGCACATAGAAACTTTGTATTGAGTGGGGATTTTGTTTTAAGTGCTGGAAAAT
TAGGGCAGGAATTACGTGTTTGCAAGTTGTTGCCATCACTGGTTTGAATTTGACTGCCTCATCAAGGGGCAAGAGTTATTCTTGAAGATC
TCATTCTCCCAGAAACAGAACTTTAGGGAAAATGGCTGTGGCTTAGCTTTTCAGCTGCTGCAGGGTAATAAGCTTTCTGGTTGGTTTTCC
TTCCAATTCTGGAAAGGTGTCCACACTAAGACCCTTAACTCTAGGGCTTGCATAAGTATTCTAGCATCGTTAGCTAATGAGTTGGTCATT
GTTTCTCTTTATCAATAATTGTGTTAATACCAATCTTATAATTTAAAAATTATCTTGTATGTAAGAGCAGTTCGGGGTTAGGGAGGAAGA
GGAGCAAAGTGGGATATTTTCTCTTTAATGCTTAGATACTGTTTCTTCCCTAAGATGTGTTTCTCAACCACAATTGGTGGAATGAACCAG
AGAGGCAAGAGGAAGTGAATTGCACCAATTTAGTTTAGCGACTGTGCCTTTTGCAGGAAAAACTGGGTGAATCACAGCTCCTCAGAGTCC
TGGACTCAACTAGAATTGAAGATAGACTTATTTTGCTGACTGGGCTTCTTAGAGTTTATGTGACTTGAACAGCTTGGCCCCTGCCTCCCT
TCTGCTACTGTGAGCAGCCTTCCTTCTTCCTTCATTCTTCCTGGAATGCAGTTCTCTTGCTTATGATCCTATGAATAAGGCAAAATGGCT
GGTCTTTGTAAGGCAGGTCTTGCCCTAGCTTCTCAGAAACAGGAGCATTTTAGGATCAGTATTAGGAGATGCCCCAGGGAGTAAGAAAGT
ATTGGGTTCAGTGATAAATCTGGACTCTGACATTTCTTTTACTCTCCCTCTTTAATACTAAAAGCTCTGCATAAGCAATGGTTCAGAACC
TGTCTTGGGTACAGACCTGTTGAATCTGACAGAAACCAGAAACGCACTTTTGAGAAAAAGACATTTGTAATTCACTCAGTTTTCCATACA
CATTTAGCAGGTTCAAAGCCCATCTGTGGAATCCCTAAACTGCCTTCAAAGAAAGGGAGTTCCCCGATCTAAAATGGTCATTATATATTT
GTGTCAAGAATTAGAAGGCAAGGGTCACTAAATATTTTAAGGATTAAGGTACCAGAGGCATCAGTGGTATAAGGATGGAGTCTGGTCTTT
AATTACGACAAGGGTATTGCTTACATTCTACTCTCTGGTTTTCAAAAAGATCTGACATGCTGACAAATCCAGCTCCTCACAAATCTTGTT
TGAAGGACTTGTGGGAAGTGATATTCCTTACTATTAGATCACGCCCCTTATAACTACATGTTAACATCCAGCCTTTTATCTGTTTGAGTA
ATTGTAGGGATAGAAAGTGAAGCCCCCAGAGTTAGGTGCAAGTATAGCACCCAGCTGAAAGGCATCATGGAGTCTAAGGGCCTTCTACAG
AAGGGGCAATCCTTTGGGTTATTTCTGGTGTACCACTGTCTTCTCTACCTCGGTCCAACACCACCTCTCTTGGACAAAAAATAAAACAAG
CAACAGCCATCAGATGAGTGAATAGATTTGAATGATTTTTCCCACAGGGAATCAGCCTCAAATGTTCATGTTTCACCCCGTCCCCTTTAA

>In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_4602nt
GCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCACCGCCGGCCCATGACTGAGCCCCGCCGCCGCCGGCCGAGGAATGGGCTCCG
GGCTCTGGTAGGAAGCGCTGGGAGCGGGGGGCGCTTTTAAAACACCGATCTGGGTTTTTTAAAAACCTCCTTTGAAAAAATAATGGCAAA
CTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGAGGGTCGCC
TTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTCGCGAAGGT
TTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAACAGTATTA
CTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAATGTACAGCT
GGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTGTGCTGTGA
CCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACTGGAGACTG
GGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAGGAGTGGCG
GAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTTCCAATTCC
CAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATTCTGAGGGT
CACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTGTCTGAAGA
TACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCTTTTCTTCA
GGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAACAGTTTGT
ATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTTGGGCGAAG
ACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGCAACTCCCA
TCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAACGGCAGCG
TGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGGCTGACCCA
CACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACCCACCAGGG
ACAAAGTCCCCGGAACAGCTGGGACAGAGGAACATCTGTCTTTTGAAATCTGTTTCCACTACAGCTATGGTCAAGTCTATCAGCCGGTGC
TACCAGGAGTCACTGCCAGGGCTGCCGTTCTCCTGAACCCCAGTGGCCAGAATCATAAGCCCTGACCCCATCCCTAGAAAGATGAGGTCC
CAGCAATGGCCAGAGCATTTCTCACCAGTTCTGTGAGATAGCACATAAAAATAGAGTTCTTTGGGCAAAACTTTTGGGAAGCAATGCATC
CTACATGGGCTGATATTCAGCCTGAGCTGTTCTCAAGAGGAGAGTGGTACTGGCAGTTTATGGCTGAAATCCATTCTGATTGGTTGGAGT
CTATGCTATACCAGTTGTTAAACATTTTGAGTATCACTCTTGCATACTGTTACTATTATATTTTCTCTATATATAGACAGAAAGGCCATT
TTAGAATATTAAAGGCTCTGAAAATTTCTGCAGTAGACCCAACTGAAGGTTCTATTAAGGCAGTGTTTCCTAAATGTATTTGACCTCAGT
ATCCTTTCTATTTACATCCCACAGAACTGGTGACTATGAAACACTCTGGTGAACACTGGGTTAGAGAGTAACAAGGAAACAAGAGATAGT
GATCAGGCATCCAGAGCCCCCTTTTTTATCCATATGAAAGCCAGGGGGGCCAGACCTTGTTCATGTGTGGGTCTGTCTTCCTTATGCCAA
TCAGCAGTATATACATCACCTCTCACCCTCACCTGCTGAAAAAATAACCTTTTTACCCATTATTCCTACTCCCTTCATCCTGCACATACA
TATATCCAGCTGAGAGATCACACTACAAGGCTAAGAGATGATCTAATACCCCCAAATAGCCCTGGCCCACACAGAAAAACAGAAAAACAA
AAAAAACTTTATCCCCTTGAACAGTCCCCTCTCTCCTCTTGACTGTCTTTATGTGTCTGTGTATTTGTGTGCAGGGTCTTTGAAGACAGC
ATGCTATGTGCAAACTGTACAAGCTAGGTTTTCTAGGGGCTGTGTTCTGGGGATGAGGGTAGTGGGGATTATATGGGGTTTTTTCTTTGT
TTCAAGACAGGAAGCAGTCTGGTTAAGGGAGAACTAGTGGAAAGGGTTAAATGACAGGTTAAGTTGAGTACAAAGCTTTCCCAGTACTGC
TGAGATTAAGACAATTGTGGATGTGTATGTCTAGGTTTGAATCTCTGGGCTGCAGATTGCTTTTGCCCTGGCAGAGAAAGAGGAGTCTTT
GGGGAGGTGAGCTGTTTCTTGTTGATTTCAGGCAAGAGGCACATAGAAACTTTGTATTGAGTGGGGATTTTGTTTTAAGTGCTGGAAAAT
TAGGGCAGGAATTACGTGTTTGCAAGTTGTTGCCATCACTGGTTTGAATTTGACTGCCTCATCAAGGGGCAAGAGTTATTCTTGAAGATC
TCATTCTCCCAGAAACAGAACTTTAGGGAAAATGGCTGTGGCTTAGCTTTTCAGCTGCTGCAGGGTAATAAGCTTTCTGGTTGGTTTTCC
TTCCAATTCTGGAAAGGTGTCCACACTAAGACCCTTAACTCTAGGGCTTGCATAAGTATTCTAGCATCGTTAGCTAATGAGTTGGTCATT
GTTTCTCTTTATCAATAATTGTGTTAATACCAATCTTATAATTTAAAAATTATCTTGTATGTAAGAGCAGTTCGGGGTTAGGGAGGAAGA
GGAGCAAAGTGGGATATTTTCTCTTTAATGCTTAGATACTGTTTCTTCCCTAAGATGTGTTTCTCAACCACAATTGGTGGAATGAACCAG
AGAGGCAAGAGGAAGTGAATTGCACCAATTTAGTTTAGCGACTGTGCCTTTTGCAGGAAAAACTGGGTGAATCACAGCTCCTCAGAGTCC
TGGACTCAACTAGAATTGAAGATAGACTTATTTTGCTGACTGGGCTTCTTAGAGTTTATGTGACTTGAACAGCTTGGCCCCTGCCTCCCT
TCTGCTACTGTGAGCAGCCTTCCTTCTTCCTTCATTCTTCCTGGAATGCAGTTCTCTTGCTTATGATCCTATGAATAAGGCAAAATGGCT
GGTCTTTGTAAGGCAGGTCTTGCCCTAGCTTCTCAGAAACAGGAGCATTTTAGGATCAGTATTAGGAGATGCCCCAGGGAGTAAGAAAGT
ATTGGGTTCAGTGATAAATCTGGACTCTGACATTTCTTTTACTCTCCCTCTTTAATACTAAAAGCTCTGCATAAGCAATGGTTCAGAACC
TGTCTTGGGTACAGACCTGTTGAATCTGACAGAAACCAGAAACGCACTTTTGAGAAAAAGACATTTGTAATTCACTCAGTTTTCCATACA
CATTTAGCAGGTTCAAAGCCCATCTGTGGAATCCCTAAACTGCCTTCAAAGAAAGGGAGTTCCCCGATCTAAAATGGTCATTATATATTT
GTGTCAAGAATTAGAAGGCAAGGGTCACTAAATATTTTAAGGATTAAGGTACCAGAGGCATCAGTGGTATAAGGATGGAGTCTGGTCTTT
AATTACGACAAGGGTATTGCTTACATTCTACTCTCTGGTTTTCAAAAAGATCTGACATGCTGACAAATCCAGCTCCTCACAAATCTTGTT
TGAAGGACTTGTGGGAAGTGATATTCCTTACTATTAGATCACGCCCCTTATAACTACATGTTAACATCCAGCCTTTTATCTGTTTGAGTA
ATTGTAGGGATAGAAAGTGAAGCCCCCAGAGTTAGGTGCAAGTATAGCACCCAGCTGAAAGGCATCATGGAGTCTAAGGGCCTTCTACAG
AAGGGGCAATCCTTTGGGTTATTTCTGGTGTACCACTGTCTTCTCTACCTCGGTCCAACACCACCTCTCTTGGACAAAAAATAAAACAAG


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FusionGenePPI for ARID2_ZNF641


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ARID2HNRNPA1, KHDRBS2, NFYC, SMARCE1, BCL7C, BRD7, CHD7, PBRM1, SMARCC2, SMARCC1, SMARCD1, SMARCB1, SMARCA4, SMARCAD1, TFAP4, DPF3, NUP50, LHX4, SS18, HIST1H3E, CD14, EGR1, KPNA1, AP4M1, TSC22D2, RRM2, VHL, BCL7A, ZNF23, TRIM25ZNF641SQLE, KDM1A, APP, DTX2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ARID2_ZNF641


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARID2_ZNF641


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARID2C2239176Liver carcinoma2CTD_human