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Fusion gene ID: 2651 |
FusionGeneSummary for ARID2_ZNF641 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARID2_ZNF641 | Fusion gene ID: 2651 | Hgene | Tgene | Gene symbol | ARID2 | ZNF641 | Gene ID | 196528 | 121274 |
| Gene name | AT-rich interaction domain 2 | zinc finger protein 641 | |
| Synonyms | BAF200|CSS6|p200 | - | |
| Cytomap | 12q12 | 12q13.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AT-rich interactive domain-containing protein 2ARID domain-containing protein 2AT rich interactive domain 2 (ARID, RFX-like)BRG1-associated factor 200zinc finger protein with activation potentialzipzap/p200 | zinc finger protein 641 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q68CP9 | Q96N77 | |
| Ensembl transtripts involved in fusion gene | ENST00000334344, ENST00000422737, ENST00000479608, ENST00000444670, ENST00000457135, | ENST00000301042, ENST00000544117, ENST00000448928, ENST00000547026, | |
| Fusion gene scores | * DoF score | 8 X 5 X 7=280 | 1 X 1 X 1=1 |
| # samples | 8 | 1 | |
| ** MAII score | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: ARID2 [Title/Abstract] AND ZNF641 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ARID2 | GO:0006337 | nucleosome disassembly | 8895581 |
| Hgene | ARID2 | GO:0008285 | negative regulation of cell proliferation | 26169693 |
| Hgene | ARID2 | GO:0030336 | negative regulation of cell migration | 26169693 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AR-A1AV-01A | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000334344 | ENST00000301042 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| In-frame | ENST00000334344 | ENST00000544117 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5CDS-5UTR | ENST00000334344 | ENST00000448928 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5CDS-5UTR | ENST00000334344 | ENST00000547026 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5UTR-3CDS | ENST00000422737 | ENST00000301042 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5UTR-3CDS | ENST00000422737 | ENST00000544117 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5UTR-5UTR | ENST00000422737 | ENST00000448928 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| 5UTR-5UTR | ENST00000422737 | ENST00000547026 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000479608 | ENST00000301042 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000479608 | ENST00000544117 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000479608 | ENST00000448928 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000479608 | ENST00000547026 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000444670 | ENST00000301042 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000444670 | ENST00000544117 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000444670 | ENST00000448928 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000444670 | ENST00000547026 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000457135 | ENST00000301042 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-3CDS | ENST00000457135 | ENST00000544117 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000457135 | ENST00000448928 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
| intron-5UTR | ENST00000457135 | ENST00000547026 | ARID2 | chr12 | 46125097 | + | ZNF641 | chr12 | 48741898 | - |
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FusionProtFeatures for ARID2_ZNF641 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARID2 | ZNF641 |
| Transcriptional activator. Activates transcriptionalactivities of SRE and AP-1. {ECO:0000269|PubMed:16343441}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 109_181 | 5 | 439 | Domain | KRAB |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 109_181 | -9 | 416 | Domain | KRAB |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 109_181 | 5 | 439 | Domain | KRAB |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 109_181 | -9 | 425 | Domain | KRAB |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 171_265 | 5 | 439 | Region | Note=Transactivation |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 171_265 | -9 | 416 | Region | Note=Transactivation |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 171_265 | 5 | 439 | Region | Note=Transactivation |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 171_265 | -9 | 425 | Region | Note=Transactivation |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 264_286 | 5 | 439 | Zinc finger | C2H2-type 1 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 292_314 | 5 | 439 | Zinc finger | C2H2-type 2 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 320_342 | 5 | 439 | Zinc finger | C2H2-type 3 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 372_394 | 5 | 439 | Zinc finger | C2H2-type 4 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000301042 | - | 1 | 7 | 400_422 | 5 | 439 | Zinc finger | C2H2-type 5 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 264_286 | -9 | 416 | Zinc finger | C2H2-type 1 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 292_314 | -9 | 416 | Zinc finger | C2H2-type 2 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 320_342 | -9 | 416 | Zinc finger | C2H2-type 3 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 372_394 | -9 | 416 | Zinc finger | C2H2-type 4 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000448928 | - | 0 | 5 | 400_422 | -9 | 416 | Zinc finger | C2H2-type 5 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 264_286 | 5 | 439 | Zinc finger | C2H2-type 1 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 292_314 | 5 | 439 | Zinc finger | C2H2-type 2 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 320_342 | 5 | 439 | Zinc finger | C2H2-type 3 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 372_394 | 5 | 439 | Zinc finger | C2H2-type 4 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000544117 | - | 0 | 6 | 400_422 | 5 | 439 | Zinc finger | C2H2-type 5 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 264_286 | -9 | 425 | Zinc finger | C2H2-type 1 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 292_314 | -9 | 425 | Zinc finger | C2H2-type 2 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 320_342 | -9 | 425 | Zinc finger | C2H2-type 3 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 372_394 | -9 | 425 | Zinc finger | C2H2-type 4 |
| Tgene | >ZNF641 | chr12:46125097 | chr12:48741898 | ENST00000547026 | - | 0 | 6 | 400_422 | -9 | 425 | Zinc finger | C2H2-type 5 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ARID2 | chr12:46125097 | chr12:48741898 | ENST00000334344 | + | 3 | 21 | 793_1128 | 94 | 1836 | Compositional bias | Note=Gln-rich |
| Hgene | >ARID2 | chr12:46125097 | chr12:48741898 | ENST00000334344 | + | 3 | 21 | 524_603 | 94 | 1836 | DNA binding | RFX-type winged-helix |
| Hgene | >ARID2 | chr12:46125097 | chr12:48741898 | ENST00000334344 | + | 3 | 21 | 13_105 | 94 | 1836 | Domain | ARID |
| Hgene | >ARID2 | chr12:46125097 | chr12:48741898 | ENST00000334344 | + | 3 | 21 | 313_317 | 94 | 1836 | Motif | Note=LXXLL |
| Hgene | >ARID2 | chr12:46125097 | chr12:48741898 | ENST00000334344 | + | 3 | 21 | 1632_1657 | 94 | 1836 | Zinc finger | Note=C2H2-type |
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FusionGeneSequence for ARID2_ZNF641 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_528aa MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALK QYYLRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNT GDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDI LRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGK QFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRK >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_528aa MANSTGKAPPDERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEEFNFPRSCSNAAFALK QYYLRSQFGSAAEMLSEQTAALGTGWESMNVQLDGAEPQVERGSQEERPWRTVPGPLEHLCCDLEEEPQSLQEKAQSAPWVPAIPQEGNT GDWEMAAALLAAGSQGLVTIKDVSLCFSQEEWRSLDPSQTDFYGEYVMQENCGIVVSLRFPIPKLDMLSQLEGGEEQWVPDPQDLEERDI LRVTYTGDGSEHEGDTPELEAEPPRMLSSVSEDTVLWNPEHDESWDSMPSSSRGMLLGPPFLQEDSFSNLLCSTEMDSLLRPHTCPQCGK QFVWGSHLARHQQTHTGERPYSCLKCEKTFGRRHHLIRHQKTHLHDKTSRCSECGKNFRCNSHLASHQRVHAEGKSCKGQEVGESPGTRK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_1584nt ATGGCAAACTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGA GGGTCGCCTTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTC GCGAAGGTTTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAA CAGTATTACTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAAT GTACAGCTGGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTG TGCTGTGACCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACT GGAGACTGGGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAG GAGTGGCGGAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTT CCAATTCCCAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATT CTGAGGGTCACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTG TCTGAAGATACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCT TTTCTTCAGGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAA CAGTTTGTATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTT GGGCGAAGACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGC AACTCCCATCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAA CGGCAGCGTGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGG CTGACCCACACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACC >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_1584nt ATGGCAAACTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGA GGGTCGCCTTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTC GCGAAGGTTTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAA CAGTATTACTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAAT GTACAGCTGGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTG TGCTGTGACCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACT GGAGACTGGGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAG GAGTGGCGGAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTT CCAATTCCCAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATT CTGAGGGTCACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTG TCTGAAGATACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCT TTTCTTCAGGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAA CAGTTTGTATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTT GGGCGAAGACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGC AACTCCCATCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAA CGGCAGCGTGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGG CTGACCCACACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000301042_chr12_48741898_-_4721nt GCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCACCGCCGGCCCATGACTGAGCCCCGCCGCCGCCGGCCGAGGAATGGGCTCCG GGCTCTGGTAGGAAGCGCTGGGAGCGGGGGGCGCTTTTAAAACACCGATCTGGGTTTTTTAAAAACCTCCTTTGAAAAAATAATGGCAAA CTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGAGGGTCGCC TTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTCGCGAAGGT TTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAACAGTATTA CTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAATGTACAGCT GGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTGTGCTGTGA CCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACTGGAGACTG GGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAGGAGTGGCG GAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTTCCAATTCC CAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATTCTGAGGGT CACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTGTCTGAAGA TACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCTTTTCTTCA GGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAACAGTTTGT ATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTTGGGCGAAG ACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGCAACTCCCA TCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAACGGCAGCG TGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGGCTGACCCA CACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACCCACCAGGG ACAAAGTCCCCGGAACAGCTGGGACAGAGGAACATCTGTCTTTTGAAATCTGTTTCCACTACAGCTATGGTCAAGTCTATCAGCCGGTGC TACCAGGAGTCACTGCCAGGGCTGCCGTTCTCCTGAACCCCAGTGGCCAGAATCATAAGCCCTGACCCCATCCCTAGAAAGATGAGGTCC CAGCAATGGCCAGAGCATTTCTCACCAGTTCTGTGAGATAGCACATAAAAATAGAGTTCTTTGGGCAAAACTTTTGGGAAGCAATGCATC CTACATGGGCTGATATTCAGCCTGAGCTGTTCTCAAGAGGAGAGTGGTACTGGCAGTTTATGGCTGAAATCCATTCTGATTGGTTGGAGT CTATGCTATACCAGTTGTTAAACATTTTGAGTATCACTCTTGCATACTGTTACTATTATATTTTCTCTATATATAGACAGAAAGGCCATT TTAGAATATTAAAGGCTCTGAAAATTTCTGCAGTAGACCCAACTGAAGGTTCTATTAAGGCAGTGTTTCCTAAATGTATTTGACCTCAGT ATCCTTTCTATTTACATCCCACAGAACTGGTGACTATGAAACACTCTGGTGAACACTGGGTTAGAGAGTAACAAGGAAACAAGAGATAGT GATCAGGCATCCAGAGCCCCCTTTTTTATCCATATGAAAGCCAGGGGGGCCAGACCTTGTTCATGTGTGGGTCTGTCTTCCTTATGCCAA TCAGCAGTATATACATCACCTCTCACCCTCACCTGCTGAAAAAATAACCTTTTTACCCATTATTCCTACTCCCTTCATCCTGCACATACA TATATCCAGCTGAGAGATCACACTACAAGGCTAAGAGATGATCTAATACCCCCAAATAGCCCTGGCCCACACAGAAAAACAGAAAAACAA AAAAAACTTTATCCCCTTGAACAGTCCCCTCTCTCCTCTTGACTGTCTTTATGTGTCTGTGTATTTGTGTGCAGGGTCTTTGAAGACAGC ATGCTATGTGCAAACTGTACAAGCTAGGTTTTCTAGGGGCTGTGTTCTGGGGATGAGGGTAGTGGGGATTATATGGGGTTTTTTCTTTGT TTCAAGACAGGAAGCAGTCTGGTTAAGGGAGAACTAGTGGAAAGGGTTAAATGACAGGTTAAGTTGAGTACAAAGCTTTCCCAGTACTGC TGAGATTAAGACAATTGTGGATGTGTATGTCTAGGTTTGAATCTCTGGGCTGCAGATTGCTTTTGCCCTGGCAGAGAAAGAGGAGTCTTT GGGGAGGTGAGCTGTTTCTTGTTGATTTCAGGCAAGAGGCACATAGAAACTTTGTATTGAGTGGGGATTTTGTTTTAAGTGCTGGAAAAT TAGGGCAGGAATTACGTGTTTGCAAGTTGTTGCCATCACTGGTTTGAATTTGACTGCCTCATCAAGGGGCAAGAGTTATTCTTGAAGATC TCATTCTCCCAGAAACAGAACTTTAGGGAAAATGGCTGTGGCTTAGCTTTTCAGCTGCTGCAGGGTAATAAGCTTTCTGGTTGGTTTTCC TTCCAATTCTGGAAAGGTGTCCACACTAAGACCCTTAACTCTAGGGCTTGCATAAGTATTCTAGCATCGTTAGCTAATGAGTTGGTCATT GTTTCTCTTTATCAATAATTGTGTTAATACCAATCTTATAATTTAAAAATTATCTTGTATGTAAGAGCAGTTCGGGGTTAGGGAGGAAGA GGAGCAAAGTGGGATATTTTCTCTTTAATGCTTAGATACTGTTTCTTCCCTAAGATGTGTTTCTCAACCACAATTGGTGGAATGAACCAG AGAGGCAAGAGGAAGTGAATTGCACCAATTTAGTTTAGCGACTGTGCCTTTTGCAGGAAAAACTGGGTGAATCACAGCTCCTCAGAGTCC TGGACTCAACTAGAATTGAAGATAGACTTATTTTGCTGACTGGGCTTCTTAGAGTTTATGTGACTTGAACAGCTTGGCCCCTGCCTCCCT TCTGCTACTGTGAGCAGCCTTCCTTCTTCCTTCATTCTTCCTGGAATGCAGTTCTCTTGCTTATGATCCTATGAATAAGGCAAAATGGCT GGTCTTTGTAAGGCAGGTCTTGCCCTAGCTTCTCAGAAACAGGAGCATTTTAGGATCAGTATTAGGAGATGCCCCAGGGAGTAAGAAAGT ATTGGGTTCAGTGATAAATCTGGACTCTGACATTTCTTTTACTCTCCCTCTTTAATACTAAAAGCTCTGCATAAGCAATGGTTCAGAACC TGTCTTGGGTACAGACCTGTTGAATCTGACAGAAACCAGAAACGCACTTTTGAGAAAAAGACATTTGTAATTCACTCAGTTTTCCATACA CATTTAGCAGGTTCAAAGCCCATCTGTGGAATCCCTAAACTGCCTTCAAAGAAAGGGAGTTCCCCGATCTAAAATGGTCATTATATATTT GTGTCAAGAATTAGAAGGCAAGGGTCACTAAATATTTTAAGGATTAAGGTACCAGAGGCATCAGTGGTATAAGGATGGAGTCTGGTCTTT AATTACGACAAGGGTATTGCTTACATTCTACTCTCTGGTTTTCAAAAAGATCTGACATGCTGACAAATCCAGCTCCTCACAAATCTTGTT TGAAGGACTTGTGGGAAGTGATATTCCTTACTATTAGATCACGCCCCTTATAACTACATGTTAACATCCAGCCTTTTATCTGTTTGAGTA ATTGTAGGGATAGAAAGTGAAGCCCCCAGAGTTAGGTGCAAGTATAGCACCCAGCTGAAAGGCATCATGGAGTCTAAGGGCCTTCTACAG AAGGGGCAATCCTTTGGGTTATTTCTGGTGTACCACTGTCTTCTCTACCTCGGTCCAACACCACCTCTCTTGGACAAAAAATAAAACAAG CAACAGCCATCAGATGAGTGAATAGATTTGAATGATTTTTCCCACAGGGAATCAGCCTCAAATGTTCATGTTTCACCCCGTCCCCTTTAA >In-frame_ARID2_ENST00000334344_chr12_46125097_+_ZNF641_ENST00000544117_chr12_48741898_-_4602nt GCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCACCGCCGGCCCATGACTGAGCCCCGCCGCCGCCGGCCGAGGAATGGGCTCCG GGCTCTGGTAGGAAGCGCTGGGAGCGGGGGGCGCTTTTAAAACACCGATCTGGGTTTTTTAAAAACCTCCTTTGAAAAAATAATGGCAAA CTCGACGGGGAAGGCGCCTCCGGACGAGCGGAGAAAGGGACTCGCTTTCCTGGACGAGCTGCGGCAGTTCCACCACAGCAGAGGGTCGCC TTTTAAAAAAATCCCTGCGGTGGGTGGGAAGGAGCTGGATCTTCACGGTCTCTACACCAGAGTCACTACTTTAGGCGGATTCGCGAAGGT TTCTGAGAAGAATCAGTGGGGAGAAATTGTTGAAGAGTTCAACTTTCCCAGAAGTTGTTCTAACGCTGCCTTTGCTTTAAAACAGTATTA CTTGCGGTCACAATTTGGGTCTGCAGCAGAAATGCTTTCAGAACAGACAGCAGCGCTGGGGACAGGATGGGAATCAATGAATGTACAGCT GGATGGAGCAGAGCCCCAGGTGGAAAGGGGAAGCCAGGAAGAGCGGCCATGGAGAACAGTACCAGGACCTCTGGAGCACCTGTGCTGTGA CCTTGAAGAGGAGCCACAGTCCCTTCAGGAGAAGGCTCAGTCTGCTCCCTGGGTTCCTGCAATTCCCCAGGAGGGGAACACTGGAGACTG GGAGATGGCAGCTGCACTTCTTGCGGCTGGATCACAGGGCCTGGTAACCATCAAGGATGTGTCACTGTGCTTCTCTCAGGAGGAGTGGCG GAGCCTGGACCCCTCTCAGACAGACTTTTATGGAGAATATGTCATGCAGGAAAACTGTGGGATAGTAGTCTCTCTGAGATTTCCAATTCC CAAACTGGACATGCTTTCTCAACTAGAAGGAGGAGAAGAACAATGGGTCCCTGACCCCCAGGACTTAGAGGAGAGGGACATTCTGAGGGT CACATATACAGGAGATGGAAGTGAACATGAGGGGGATACCCCTGAACTAGAAGCAGAACCTCCCAGAATGTTATCCAGCGTGTCTGAAGA TACTGTTCTCTGGAACCCGGAGCATGATGAGAGCTGGGATTCCATGCCCAGCAGCTCCAGAGGAATGCTCCTGGGGCCCCCTTTTCTTCA GGAAGATAGTTTCTCAAACCTGCTGTGTAGCACAGAGATGGATTCCCTGTTAAGACCCCACACATGCCCCCAGTGTGGGAAACAGTTTGT ATGGGGTTCCCACCTTGCCAGGCATCAACAAACACACACTGGGGAGAGACCCTACAGCTGCCTCAAGTGTGAGAAGACCTTTGGGCGAAG ACATCACCTCATCAGGCACCAGAAAACCCACCTACATGACAAGACCAGCAGGTGCTCTGAGTGTGGTAAGAATTTCCGATGCAACTCCCA TCTGGCCAGCCACCAGAGAGTGCATGCAGAAGGCAAATCCTGCAAAGGCCAAGAGGTTGGAGAGAGCCCTGGCACAAGGAAACGGCAGCG TGCCCCACCAGTGCCAAAGTGTCACGTGTGCACTGAATGTGGGAAGAGCTTTGGCCGAAGGCACCACCTTGTGAGACACTGGCTGACCCA CACTGGGGAGAAGCCCTTCCAGTGCCCTCGCTGTGAGAAGAGCTTTGGCCGAAAACATCACCTGGACAGGCACCTGCTCACCCACCAGGG ACAAAGTCCCCGGAACAGCTGGGACAGAGGAACATCTGTCTTTTGAAATCTGTTTCCACTACAGCTATGGTCAAGTCTATCAGCCGGTGC TACCAGGAGTCACTGCCAGGGCTGCCGTTCTCCTGAACCCCAGTGGCCAGAATCATAAGCCCTGACCCCATCCCTAGAAAGATGAGGTCC CAGCAATGGCCAGAGCATTTCTCACCAGTTCTGTGAGATAGCACATAAAAATAGAGTTCTTTGGGCAAAACTTTTGGGAAGCAATGCATC CTACATGGGCTGATATTCAGCCTGAGCTGTTCTCAAGAGGAGAGTGGTACTGGCAGTTTATGGCTGAAATCCATTCTGATTGGTTGGAGT CTATGCTATACCAGTTGTTAAACATTTTGAGTATCACTCTTGCATACTGTTACTATTATATTTTCTCTATATATAGACAGAAAGGCCATT TTAGAATATTAAAGGCTCTGAAAATTTCTGCAGTAGACCCAACTGAAGGTTCTATTAAGGCAGTGTTTCCTAAATGTATTTGACCTCAGT ATCCTTTCTATTTACATCCCACAGAACTGGTGACTATGAAACACTCTGGTGAACACTGGGTTAGAGAGTAACAAGGAAACAAGAGATAGT GATCAGGCATCCAGAGCCCCCTTTTTTATCCATATGAAAGCCAGGGGGGCCAGACCTTGTTCATGTGTGGGTCTGTCTTCCTTATGCCAA TCAGCAGTATATACATCACCTCTCACCCTCACCTGCTGAAAAAATAACCTTTTTACCCATTATTCCTACTCCCTTCATCCTGCACATACA TATATCCAGCTGAGAGATCACACTACAAGGCTAAGAGATGATCTAATACCCCCAAATAGCCCTGGCCCACACAGAAAAACAGAAAAACAA AAAAAACTTTATCCCCTTGAACAGTCCCCTCTCTCCTCTTGACTGTCTTTATGTGTCTGTGTATTTGTGTGCAGGGTCTTTGAAGACAGC ATGCTATGTGCAAACTGTACAAGCTAGGTTTTCTAGGGGCTGTGTTCTGGGGATGAGGGTAGTGGGGATTATATGGGGTTTTTTCTTTGT TTCAAGACAGGAAGCAGTCTGGTTAAGGGAGAACTAGTGGAAAGGGTTAAATGACAGGTTAAGTTGAGTACAAAGCTTTCCCAGTACTGC TGAGATTAAGACAATTGTGGATGTGTATGTCTAGGTTTGAATCTCTGGGCTGCAGATTGCTTTTGCCCTGGCAGAGAAAGAGGAGTCTTT GGGGAGGTGAGCTGTTTCTTGTTGATTTCAGGCAAGAGGCACATAGAAACTTTGTATTGAGTGGGGATTTTGTTTTAAGTGCTGGAAAAT TAGGGCAGGAATTACGTGTTTGCAAGTTGTTGCCATCACTGGTTTGAATTTGACTGCCTCATCAAGGGGCAAGAGTTATTCTTGAAGATC TCATTCTCCCAGAAACAGAACTTTAGGGAAAATGGCTGTGGCTTAGCTTTTCAGCTGCTGCAGGGTAATAAGCTTTCTGGTTGGTTTTCC TTCCAATTCTGGAAAGGTGTCCACACTAAGACCCTTAACTCTAGGGCTTGCATAAGTATTCTAGCATCGTTAGCTAATGAGTTGGTCATT GTTTCTCTTTATCAATAATTGTGTTAATACCAATCTTATAATTTAAAAATTATCTTGTATGTAAGAGCAGTTCGGGGTTAGGGAGGAAGA GGAGCAAAGTGGGATATTTTCTCTTTAATGCTTAGATACTGTTTCTTCCCTAAGATGTGTTTCTCAACCACAATTGGTGGAATGAACCAG AGAGGCAAGAGGAAGTGAATTGCACCAATTTAGTTTAGCGACTGTGCCTTTTGCAGGAAAAACTGGGTGAATCACAGCTCCTCAGAGTCC TGGACTCAACTAGAATTGAAGATAGACTTATTTTGCTGACTGGGCTTCTTAGAGTTTATGTGACTTGAACAGCTTGGCCCCTGCCTCCCT TCTGCTACTGTGAGCAGCCTTCCTTCTTCCTTCATTCTTCCTGGAATGCAGTTCTCTTGCTTATGATCCTATGAATAAGGCAAAATGGCT GGTCTTTGTAAGGCAGGTCTTGCCCTAGCTTCTCAGAAACAGGAGCATTTTAGGATCAGTATTAGGAGATGCCCCAGGGAGTAAGAAAGT ATTGGGTTCAGTGATAAATCTGGACTCTGACATTTCTTTTACTCTCCCTCTTTAATACTAAAAGCTCTGCATAAGCAATGGTTCAGAACC TGTCTTGGGTACAGACCTGTTGAATCTGACAGAAACCAGAAACGCACTTTTGAGAAAAAGACATTTGTAATTCACTCAGTTTTCCATACA CATTTAGCAGGTTCAAAGCCCATCTGTGGAATCCCTAAACTGCCTTCAAAGAAAGGGAGTTCCCCGATCTAAAATGGTCATTATATATTT GTGTCAAGAATTAGAAGGCAAGGGTCACTAAATATTTTAAGGATTAAGGTACCAGAGGCATCAGTGGTATAAGGATGGAGTCTGGTCTTT AATTACGACAAGGGTATTGCTTACATTCTACTCTCTGGTTTTCAAAAAGATCTGACATGCTGACAAATCCAGCTCCTCACAAATCTTGTT TGAAGGACTTGTGGGAAGTGATATTCCTTACTATTAGATCACGCCCCTTATAACTACATGTTAACATCCAGCCTTTTATCTGTTTGAGTA ATTGTAGGGATAGAAAGTGAAGCCCCCAGAGTTAGGTGCAAGTATAGCACCCAGCTGAAAGGCATCATGGAGTCTAAGGGCCTTCTACAG AAGGGGCAATCCTTTGGGTTATTTCTGGTGTACCACTGTCTTCTCTACCTCGGTCCAACACCACCTCTCTTGGACAAAAAATAAAACAAG |
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FusionGenePPI for ARID2_ZNF641 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ARID2 | HNRNPA1, KHDRBS2, NFYC, SMARCE1, BCL7C, BRD7, CHD7, PBRM1, SMARCC2, SMARCC1, SMARCD1, SMARCB1, SMARCA4, SMARCAD1, TFAP4, DPF3, NUP50, LHX4, SS18, HIST1H3E, CD14, EGR1, KPNA1, AP4M1, TSC22D2, RRM2, VHL, BCL7A, ZNF23, TRIM25 | ZNF641 | SQLE, KDM1A, APP, DTX2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ARID2_ZNF641 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ARID2_ZNF641 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ARID2 | C2239176 | Liver carcinoma | 2 | CTD_human |
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