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Fusion gene ID: 26433 |
FusionGeneSummary for PDE7A_TRIM55 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PDE7A_TRIM55 | Fusion gene ID: 26433 | Hgene | Tgene | Gene symbol | PDE7A | TRIM55 | Gene ID | 5150 | 84675 |
| Gene name | phosphodiesterase 7A | tripartite motif containing 55 | |
| Synonyms | HCP1|PDE7 | MURF-2|RNF29|muRF2 | |
| Cytomap | 8q13.1 | 8q13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7ATM22phosphodiesterase isozyme 7 | tripartite motif-containing protein 55muscle specific ring finger 2muscle-specific RING finger protein 2ring finger protein 29 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q13946 | Q9BYV6 | |
| Ensembl transtripts involved in fusion gene | ENST00000401827, ENST00000396642, ENST00000379419, ENST00000518667, | ENST00000353317, ENST00000315962, ENST00000276573, ENST00000350034, | |
| Fusion gene scores | * DoF score | 8 X 6 X 5=240 | 3 X 3 X 3=27 |
| # samples | 8 | 3 | |
| ** MAII score | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PDE7A [Title/Abstract] AND TRIM55 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A2-A04P-01A | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000401827 | ENST00000353317 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| In-frame | ENST00000401827 | ENST00000315962 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| In-frame | ENST00000401827 | ENST00000276573 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| 5CDS-intron | ENST00000401827 | ENST00000350034 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| In-frame | ENST00000396642 | ENST00000353317 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| In-frame | ENST00000396642 | ENST00000315962 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| In-frame | ENST00000396642 | ENST00000276573 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| 5CDS-intron | ENST00000396642 | ENST00000350034 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000379419 | ENST00000353317 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000379419 | ENST00000315962 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000379419 | ENST00000276573 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-intron | ENST00000379419 | ENST00000350034 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000518667 | ENST00000353317 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000518667 | ENST00000315962 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-3CDS | ENST00000518667 | ENST00000276573 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
| intron-intron | ENST00000518667 | ENST00000350034 | PDE7A | chr8 | 66753606 | - | TRIM55 | chr8 | 67061880 | + |
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FusionProtFeatures for PDE7A_TRIM55 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PDE7A | TRIM55 |
| Hydrolyzes the second messenger cAMP, which is a keyregulator of many important physiological processes. May have arole in muscle signal transduction. {ECO:0000269|PubMed:19350606}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PDE7A | chr8:66753606 | chr8:67061880 | ENST00000396642 | - | 1 | 12 | 28_33 | 46 | 425 | Compositional bias | Note=Poly-Ser |
| Hgene | PDE7A | chr8:66753606 | chr8:67061880 | ENST00000401827 | - | 1 | 13 | 28_33 | 46 | 483 | Compositional bias | Note=Poly-Ser |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000350034 | + | 0 | 5 | 168_248 | -76 | 242 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000276573 | + | 3 | 11 | 269_327 | 201 | 541 | Domain | COS |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000315962 | + | 3 | 10 | 269_327 | 201 | 549 | Domain | COS |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000350034 | + | 0 | 5 | 269_327 | -76 | 242 | Domain | COS |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000353317 | + | 3 | 9 | 269_327 | 201 | 453 | Domain | COS |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000350034 | + | 0 | 5 | 103_145 | -76 | 242 | Zinc finger | B box-type |
| Tgene | >TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000350034 | + | 0 | 5 | 10_66 | -76 | 242 | Zinc finger | RING-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PDE7A | chr8:66753606 | chr8:67061880 | ENST00000379419 | - | 1 | 13 | 28_33 | -48 | 457 | Compositional bias | Note=Poly-Ser |
| Hgene | >PDE7A | chr8:66753606 | chr8:67061880 | ENST00000379419 | - | 1 | 13 | 136_458 | -48 | 457 | Domain | PDEase |
| Hgene | >PDE7A | chr8:66753606 | chr8:67061880 | ENST00000396642 | - | 1 | 12 | 136_458 | 46 | 425 | Domain | PDEase |
| Hgene | >PDE7A | chr8:66753606 | chr8:67061880 | ENST00000401827 | - | 1 | 13 | 136_458 | 46 | 483 | Domain | PDEase |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000276573 | + | 3 | 11 | 168_248 | 201 | 541 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000315962 | + | 3 | 10 | 168_248 | 201 | 549 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000353317 | + | 3 | 9 | 168_248 | 201 | 453 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000276573 | + | 3 | 11 | 103_145 | 201 | 541 | Zinc finger | B box-type |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000276573 | + | 3 | 11 | 10_66 | 201 | 541 | Zinc finger | RING-type |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000315962 | + | 3 | 10 | 103_145 | 201 | 549 | Zinc finger | B box-type |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000315962 | + | 3 | 10 | 10_66 | 201 | 549 | Zinc finger | RING-type |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000353317 | + | 3 | 9 | 103_145 | 201 | 453 | Zinc finger | B box-type |
| Tgene | TRIM55 | chr8:66753606 | chr8:67061880 | ENST00000353317 | + | 3 | 9 | 10_66 | 201 | 453 | Zinc finger | RING-type |
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FusionGeneSequence for PDE7A_TRIM55 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_298aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQIGFEAPPLQGQAA >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_394aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPTGSEQTTE SETPVPAAAETADPLFYPSWYKGQTRKATTNPPCTPGSEGLGQIGPPGSEDSNVRKAEVAAAAASERAAVSGKETSAPAATSQIGFEAPP >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_386aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPTGSEQTTE SETPVPAAAETADPLFYPSWYKGQTRKATTNPPCTPGSEGLGQIGPPGSEDSNVRKAEVAAAAASERAAVSGKETSAPAATSQELVICLA >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_298aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQIGFEAPPLQGQAA >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_394aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPTGSEQTTE SETPVPAAAETADPLFYPSWYKGQTRKATTNPPCTPGSEGLGQIGPPGSEDSNVRKAEVAAAAASERAAVSGKETSAPAATSQIGFEAPP >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_386aa MEVCYQLPVLPLDRPVPQHVLSRRGAISFSSSSALFGCPNPRQLSQECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEHVR ALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE EEGGEGEKEGEGEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGALPVSSPEPPPALPPAADAPVTQGEVVPTGSEQTTE SETPVPAAAETADPLFYPSWYKGQTRKATTNPPCTPGSEGLGQIGPPGSEDSNVRKAEVAAAAASERAAVSGKETSAPAATSQELVICLA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_894nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGATTGGATTTGAGGCTCCTCCCCTCCAGGGACAGGCTGCA >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_1182nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGATTGGATTTGAGGCTCCTCCC CTCCAGGGACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCC >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_1158nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGGAGTTAGTAATCTGCCTAGCG >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_894nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGATTGGATTTGAGGCTCCTCCCCTCCAGGGACAGGCTGCA >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_1182nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGATTGGATTTGAGGCTCCTCCC CTCCAGGGACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCC >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_1158nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGGAGTTAGTAATCTGCCTAGCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_2230nt GCTGCTCCTGAGTCCCGCGCGCCCTGGGTCTGGCCGCTGGCTCCAGCTGTCTTTTCTTGCACTGCTTTGCTCCGTTCGTGCTGCGCTCGA ACTCTGCAGTCCGGGTACCTGCTCCTCTCGGCCGAGGAGCCCCAGGGCGGCGGGGTTCCCTTTCCGACTTTGCCTGTGCTGGCCCCGCTT GCACCCCGTCCCCCCTCGCCTGGAGCGAGGCGCGCGCCGGTCCTGGTAATTGGCGCCGCGGCCGCCGCGGAGCCTTCCCGCCGGCGGCCC GAGCGGAGGGCTGGGGTTGGGGAGGCGTGAGCGCGGCTTCCCAGCCCGGGGTCGGTCCCCGCCCGCCCTGCCCCCGTCTCGGCCCGGAGC CCCCGAGCCGCGGCCCCCTCCCACTGCAGGGGCCGGCGGCCGCGGCAGGGCGGGCGCCGCGCGGAGGCAGGGCGGGCGTATTCAATGGAA GTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGCTCCAGC TCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTTGATTAC CTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGTGCTCTG ATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCAGTGTTT CTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAGAACATG AACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAAGAAGAA GGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAGTTTCCA GGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCTCCAGAG CCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGATTGGATTTGAGGCTCCTCCCCTCCAGGGACAGGCTGCAGCTCCA GCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCCCTAAATGAATGATATTCATTCCAA CTGCTGCCCCTCTGTCTGCCTGGCTGAGATGCATGTGGGCAGCAGGAAGCCCAAGTGAAATTAATATTATGCAGATGATGAAAGGGACCT CTGAACAGGATTTCTGCAAAAATAGCCCCAAACTGCAATTCCATATGACTTATCTAACATCTTGGGGGGAAAGAATATTTTGAGAAAATA GTTGCAGAAAGCACTGGAAATAATAAACTTGATCTTATACAAATCTTCTATTGTGTGGAAAATGTTGTGAAGGGTGTGTAGGTGTGGTAC ATGTGTATGTCACTAACAAGTGGCAAATGGTGAAAAAAGTGGTCACTATGCTTTTGTCTCTCATAGGCACTGACTTTTTGTTATTATATT ATGGTAGCTTTCATTTCCTTTACTCTTTAACAGTGCAGGTGGTCAGTGAAAATCAGTGTCAACTCAGAAGTGACTGATTTATCAATACAT GGACAAAAAGTAAATCATTGACCAAAGCTATGAAATGTTTCACAAAGTTTTCCTCTTTTGCATAACAGATGTCACTGGATGTACATTCAG AAATGTTCTTTGAATTTGGTGACACTTTCATGGTCCAGAAAGCTGAAGGCCTGGGCATCTCTTGTGACATTTTTCTAATATTAGTTTTAG ATTTTCACGTATTAGGCACTTTAGTTGAATCTTCCAGCAAAAGCTGTCTACTTTCTCTTTTATTCACTGTGGCACCAATCTGGTAAATTG TAGAACAATTGCATGTGTTTAAATATATATACAAACATATCACACATTAAATATATATATATTTAAATCATGCTTTGTTAATATTTGTCC >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_2518nt GCTGCTCCTGAGTCCCGCGCGCCCTGGGTCTGGCCGCTGGCTCCAGCTGTCTTTTCTTGCACTGCTTTGCTCCGTTCGTGCTGCGCTCGA ACTCTGCAGTCCGGGTACCTGCTCCTCTCGGCCGAGGAGCCCCAGGGCGGCGGGGTTCCCTTTCCGACTTTGCCTGTGCTGGCCCCGCTT GCACCCCGTCCCCCCTCGCCTGGAGCGAGGCGCGCGCCGGTCCTGGTAATTGGCGCCGCGGCCGCCGCGGAGCCTTCCCGCCGGCGGCCC GAGCGGAGGGCTGGGGTTGGGGAGGCGTGAGCGCGGCTTCCCAGCCCGGGGTCGGTCCCCGCCCGCCCTGCCCCCGTCTCGGCCCGGAGC CCCCGAGCCGCGGCCCCCTCCCACTGCAGGGGCCGGCGGCCGCGGCAGGGCGGGCGCCGCGCGGAGGCAGGGCGGGCGTATTCAATGGAA GTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGCTCCAGC TCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTTGATTAC CTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGTGCTCTG ATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCAGTGTTT CTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAGAACATG AACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAAGAAGAA GGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAGTTTCCA GGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCTCCAGAG CCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAGTCTGAA ACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACCAACCCA CCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCAGCAGCC GCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGATTGGATTTGAGGCTCCTCCCCTCCAG GGACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCCCTAAAT GAATGATATTCATTCCAACTGCTGCCCCTCTGTCTGCCTGGCTGAGATGCATGTGGGCAGCAGGAAGCCCAAGTGAAATTAATATTATGC AGATGATGAAAGGGACCTCTGAACAGGATTTCTGCAAAAATAGCCCCAAACTGCAATTCCATATGACTTATCTAACATCTTGGGGGGAAA GAATATTTTGAGAAAATAGTTGCAGAAAGCACTGGAAATAATAAACTTGATCTTATACAAATCTTCTATTGTGTGGAAAATGTTGTGAAG GGTGTGTAGGTGTGGTACATGTGTATGTCACTAACAAGTGGCAAATGGTGAAAAAAGTGGTCACTATGCTTTTGTCTCTCATAGGCACTG ACTTTTTGTTATTATATTATGGTAGCTTTCATTTCCTTTACTCTTTAACAGTGCAGGTGGTCAGTGAAAATCAGTGTCAACTCAGAAGTG ACTGATTTATCAATACATGGACAAAAAGTAAATCATTGACCAAAGCTATGAAATGTTTCACAAAGTTTTCCTCTTTTGCATAACAGATGT CACTGGATGTACATTCAGAAATGTTCTTTGAATTTGGTGACACTTTCATGGTCCAGAAAGCTGAAGGCCTGGGCATCTCTTGTGACATTT TTCTAATATTAGTTTTAGATTTTCACGTATTAGGCACTTTAGTTGAATCTTCCAGCAAAAGCTGTCTACTTTCTCTTTTATTCACTGTGG CACCAATCTGGTAAATTGTAGAACAATTGCATGTGTTTAAATATATATACAAACATATCACACATTAAATATATATATATTTAAATCATG >In-frame_PDE7A_ENST00000401827_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_1713nt GCTGCTCCTGAGTCCCGCGCGCCCTGGGTCTGGCCGCTGGCTCCAGCTGTCTTTTCTTGCACTGCTTTGCTCCGTTCGTGCTGCGCTCGA ACTCTGCAGTCCGGGTACCTGCTCCTCTCGGCCGAGGAGCCCCAGGGCGGCGGGGTTCCCTTTCCGACTTTGCCTGTGCTGGCCCCGCTT GCACCCCGTCCCCCCTCGCCTGGAGCGAGGCGCGCGCCGGTCCTGGTAATTGGCGCCGCGGCCGCCGCGGAGCCTTCCCGCCGGCGGCCC GAGCGGAGGGCTGGGGTTGGGGAGGCGTGAGCGCGGCTTCCCAGCCCGGGGTCGGTCCCCGCCCGCCCTGCCCCCGTCTCGGCCCGGAGC CCCCGAGCCGCGGCCCCCTCCCACTGCAGGGGCCGGCGGCCGCGGCAGGGCGGGCGCCGCGCGGAGGCAGGGCGGGCGTATTCAATGGAA GTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGCTCCAGC TCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTTGATTAC CTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGTGCTCTG ATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCAGTGTTT CTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAGAACATG AACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAAGAAGAA GGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAGTTTCCA GGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCTCCAGAG CCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAGTCTGAA ACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACCAACCCA CCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCAGCAGCC GCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGGAGTTAGTAATCTGCCTAGCGCTTTTG GCTTTTCTTATTCTTCACTACATCTGGAGTCAGATTCAGTGCTTGATTTTTACTTTAATGGATTGGATTTGAGGCTCCTCCCCTCCAGGG ACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCCCTAAATGA >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000353317_chr8_67061880_+_1786nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGATTGGATTTGAGGCTCCTCCCCTCCAGGGACAGGCTGCA GCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCCCTAAATGAATGATATTCA TTCCAACTGCTGCCCCTCTGTCTGCCTGGCTGAGATGCATGTGGGCAGCAGGAAGCCCAAGTGAAATTAATATTATGCAGATGATGAAAG GGACCTCTGAACAGGATTTCTGCAAAAATAGCCCCAAACTGCAATTCCATATGACTTATCTAACATCTTGGGGGGAAAGAATATTTTGAG AAAATAGTTGCAGAAAGCACTGGAAATAATAAACTTGATCTTATACAAATCTTCTATTGTGTGGAAAATGTTGTGAAGGGTGTGTAGGTG TGGTACATGTGTATGTCACTAACAAGTGGCAAATGGTGAAAAAAGTGGTCACTATGCTTTTGTCTCTCATAGGCACTGACTTTTTGTTAT TATATTATGGTAGCTTTCATTTCCTTTACTCTTTAACAGTGCAGGTGGTCAGTGAAAATCAGTGTCAACTCAGAAGTGACTGATTTATCA ATACATGGACAAAAAGTAAATCATTGACCAAAGCTATGAAATGTTTCACAAAGTTTTCCTCTTTTGCATAACAGATGTCACTGGATGTAC ATTCAGAAATGTTCTTTGAATTTGGTGACACTTTCATGGTCCAGAAAGCTGAAGGCCTGGGCATCTCTTGTGACATTTTTCTAATATTAG TTTTAGATTTTCACGTATTAGGCACTTTAGTTGAATCTTCCAGCAAAAGCTGTCTACTTTCTCTTTTATTCACTGTGGCACCAATCTGGT AAATTGTAGAACAATTGCATGTGTTTAAATATATATACAAACATATCACACATTAAATATATATATATTTAAATCATGCTTTGTTAATAT >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000315962_chr8_67061880_+_2074nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGATTGGATTTGAGGCTCCTCCC CTCCAGGGACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCC CTAAATGAATGATATTCATTCCAACTGCTGCCCCTCTGTCTGCCTGGCTGAGATGCATGTGGGCAGCAGGAAGCCCAAGTGAAATTAATA TTATGCAGATGATGAAAGGGACCTCTGAACAGGATTTCTGCAAAAATAGCCCCAAACTGCAATTCCATATGACTTATCTAACATCTTGGG GGGAAAGAATATTTTGAGAAAATAGTTGCAGAAAGCACTGGAAATAATAAACTTGATCTTATACAAATCTTCTATTGTGTGGAAAATGTT GTGAAGGGTGTGTAGGTGTGGTACATGTGTATGTCACTAACAAGTGGCAAATGGTGAAAAAAGTGGTCACTATGCTTTTGTCTCTCATAG GCACTGACTTTTTGTTATTATATTATGGTAGCTTTCATTTCCTTTACTCTTTAACAGTGCAGGTGGTCAGTGAAAATCAGTGTCAACTCA GAAGTGACTGATTTATCAATACATGGACAAAAAGTAAATCATTGACCAAAGCTATGAAATGTTTCACAAAGTTTTCCTCTTTTGCATAAC AGATGTCACTGGATGTACATTCAGAAATGTTCTTTGAATTTGGTGACACTTTCATGGTCCAGAAAGCTGAAGGCCTGGGCATCTCTTGTG ACATTTTTCTAATATTAGTTTTAGATTTTCACGTATTAGGCACTTTAGTTGAATCTTCCAGCAAAAGCTGTCTACTTTCTCTTTTATTCA CTGTGGCACCAATCTGGTAAATTGTAGAACAATTGCATGTGTTTAAATATATATACAAACATATCACACATTAAATATATATATATTTAA ATCATGCTTTGTTAATATTTGTCCCACCATAATGCCTCCTTCAGAACATAAGTGTAACTTTATATGAACTCTTAAATAAATGATGTTTTT >In-frame_PDE7A_ENST00000396642_chr8_66753606_-_TRIM55_ENST00000276573_chr8_67061880_+_1269nt ATGGAAGTGTGTTACCAGCTGCCGGTACTGCCCCTGGACAGGCCGGTCCCCCAGCACGTCCTCAGCCGCCGAGGAGCCATCAGCTTCAGC TCCAGCTCCGCTCTCTTCGGCTGCCCCAATCCCCGGCAGCTCTCTCAGGAATGTTGCAGAAAACAGAAACAAGAGCTTTGTGAGAAGTTT GATTACCTGTATGGCATTTTGGAGGAGAGGAAGAATGAAATGACCCAAGTCATTACCCGAACCCAAGAGGAGAAACTGGAACATGTCCGT GCTCTGATCAAAAAGTATTCTGATCATTTGGAGAACGTCTCAAAGTTGGTTGAGTCAGGAATTCAGTTTATGGATGAGCCAGAAATGGCA GTGTTTCTGCAGAATGCCAAAACCCTGCTAAAAAAAATCTCGGAAGCATCAAAGGCATTTCAGATGGAGAAAATAGAACATGGCTATGAG AACATGAACCACTTCACAGTCAACCTCAATAGAGAAGAAAAGATAATACGTGAAATTGACTTTTACAGAGAAGATGAAGATGAAGAAGAA GAAGAAGGCGGAGAAGGAGAAAAAGAAGGAGAAGGAGAAGTGGGAGGAGAAGCAGTAGAAGTGGAAGAGGTAGAAAATGTTCAAACAGAG TTTCCAGGAGAAGATGAAAACCCAGAAAAAGCTTCAGAGCTCTCTCAGGTGGAGCTGCAGGCTGCCCCTGGGGCACTTCCAGTTTCCTCT CCAGAGCCACCTCCAGCCCTGCCACCTGCTGCGGATGCCCCTGTGACACAGGGGGAGGTTGTACCCACTGGCTCTGAGCAGACCACAGAG TCTGAAACTCCAGTCCCTGCAGCAGCAGAAACTGCGGATCCCTTGTTTTACCCTAGTTGGTATAAAGGCCAAACCCGGAAAGCCACCACC AACCCACCTTGCACCCCAGGGAGCGAAGGTCTGGGGCAAATAGGGCCTCCAGGTTCTGAGGATTCGAATGTACGGAAGGCAGAAGTGGCA GCAGCCGCAGCGAGTGAGAGGGCAGCTGTGAGTGGTAAGGAAACTAGTGCACCTGCAGCTACTTCTCAGGAGTTAGTAATCTGCCTAGCG CTTTTGGCTTTTCTTATTCTTCACTACATCTGGAGTCAGATTCAGTGCTTGATTTTTACTTTAATGGATTGGATTTGAGGCTCCTCCCCT CCAGGGACAGGCTGCAGCTCCAGCGAGTGGCAGTGGAGCTGATTCTGAGCCAGCTCGCCATATCTTCTCCTTTTCCTGGTTGAACTCCCT |
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FusionGenePPI for PDE7A_TRIM55 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PDE7A | UBXN11, VPS13A, THBS3, DCAF8 | TRIM55 | UBE2I, USP13, TRIM63, UBE2D1, UBE2D2, UBE2D3, SQSTM1, USP5, ATXN3, USP7, OTUB1, UCHL3, USP8, UCHL5, OTUB2, ATXN3L, USP28, ESPL1, STAM, YOD1, USP4, HNRNPC, SAFB, SRSF11, SRSF7, SEPT7, SRSF10, NCSTN, HNRNPU, PRPF8, NHP2L1, SAP18, SF3A1, SEPT2, PRPF19, USP39, THOC6, BUD31, PHGDH, S100A9, NFIA, SF3B6, CDC5L, SRSF1, RANBP2, DHX9, SF3B3, TRIM55, BRAP, MDM4, PCGF1, RNF114, TRIM27, DES, ACTA1, MYOT, TNNI3, TNNI2, TNNI1, MYBPC3, MYBPC1, TTN, TCAP, NEB, NEBL, FLNA, FLNB, FLNC, ANKRD1, FHL2, MYOZ1, PIAS1, PIAS3, PIAS2, DCAF6, UXT, GMEB1, LMCD1, NOMO1, EEF1G, GFM1, EIF3E, MRPL41, MRPL19, EHHADH, ATP5B, NDUFA1, CKM |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PDE7A_TRIM55 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | PDE7A | Q13946 | DB00651 | Dyphylline | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | small molecule | approved |
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RelatedDiseases for PDE7A_TRIM55 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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