FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 26089

FusionGeneSummary for PAX8_PPARG

check button Fusion gene summary
Fusion gene informationFusion gene name: PAX8_PPARG
Fusion gene ID: 26089
HgeneTgene
Gene symbol

PAX8

PPARG

Gene ID

7849

5468

Gene namepaired box 8peroxisome proliferator activated receptor gamma
Synonyms-CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma
Cytomap

2q14.1

3p25.2

Type of geneprotein-codingprotein-coding
Descriptionpaired box protein Pax-8paired domain gene 8peroxisome proliferator-activated receptor gammaPPAR-gammanuclear receptor subfamily 1 group C member 3peroxisome proliferator-activated nuclear receptor gamma variant 1
Modification date2018051920180523
UniProtAcc

Q06710

P37231

Ensembl transtripts involved in fusion geneENST00000348715, ENST00000397647, 
ENST00000263335, ENST00000429538, 
ENST00000263334, 		ENST00000397010, 
ENST00000309576, ENST00000397015, 
ENST00000397012, ENST00000397026, 
ENST00000397000, ENST00000539812, 
ENST00000287820, 
Fusion gene scores* DoF score7 X 8 X 4=2248 X 5 X 4=160
# samples 1313
** MAII scorelog2(13/224*10)=-0.784987109029149
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/160*10)=-0.299560281858908
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAX8 [Title/Abstract] AND PPARG [Title/Abstract] AND fusion [Title/Abstract]

Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. (pmid: 16609007)
Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePAX8

GO:0006351

transcription, DNA-templated

9590296

HgenePAX8

GO:0045893

positive regulation of transcription, DNA-templated

9388203|15356023|15961562

HgenePAX8

GO:0045944

positive regulation of transcription by RNA polymerase II

9388203

HgenePAX8

GO:0071371

cellular response to gonadotropin stimulus

15961562

TgenePPARG

GO:0000122

negative regulation of transcription by RNA polymerase II

12700342

TgenePPARG

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

18293083

TgenePPARG

GO:0007165

signal transduction

9568716

TgenePPARG

GO:0010742

macrophage derived foam cell differentiation

26504087

TgenePPARG

GO:0010745

negative regulation of macrophage derived foam cell differentiation

19114110

TgenePPARG

GO:0010871

negative regulation of receptor biosynthetic process

12700342

TgenePPARG

GO:0010887

negative regulation of cholesterol storage

19114110

TgenePPARG

GO:0010891

negative regulation of sequestering of triglyceride

12700342

TgenePPARG

GO:0016525

negative regulation of angiogenesis

28566713

TgenePPARG

GO:0030224

monocyte differentiation

9568716

TgenePPARG

GO:0032526

response to retinoic acid

16239304

TgenePPARG

GO:0042953

lipoprotein transport

9568716

TgenePPARG

GO:0043537

negative regulation of blood vessel endothelial cell migration

28566713

TgenePPARG

GO:0045713

low-density lipoprotein particle receptor biosynthetic process

9568716

TgenePPARG

GO:0045944

positive regulation of transcription by RNA polymerase II

9568715|12700342|16239304|17611579

TgenePPARG

GO:0048469

cell maturation

9568716

TgenePPARG

GO:0048662

negative regulation of smooth muscle cell proliferation

20622039

TgenePPARG

GO:0051091

positive regulation of DNA binding transcription factor activity

18293083

TgenePPARG

GO:0061614

pri-miRNA transcription by RNA polymerase II

28566713

TgenePPARG

GO:0071404

cellular response to low-density lipoprotein particle stimulus

9568716

TgenePPARG

GO:1904706

negative regulation of vascular smooth muscle cell proliferation

28522568


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVTHCATCGA-ET-A39N-01APAX8chr2

113992971

-PPARGchr3

12421203

+
TCGARVTHCATCGA-BJ-A0YZ-01APAX8chr2

113994178

-PPARGchr3

12421203

+
TCGARVTHCATCGA-EM-A3AJ-01APAX8chr2

113992971

-PPARGchr3

12421203

+
TCGARVTHCATCGA-BJ-A0ZF-01APAX8chr2

113992971

-PPARGchr3

12421203

+
TCGARVTHCATCGA-DE-A4M9-01APAX8chr2

113992971

-PPARGchr3

12421203

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000348715ENST00000397010PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000309576PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397015PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397012PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397026PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397000PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000539812PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000287820PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397010PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000309576PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397015PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397012PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397026PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397000PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000539812PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000287820PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397010PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000309576PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397015PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397012PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397026PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397000PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000539812PAX8chr2

113992971

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000287820PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397010PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000309576PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397015PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397012PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397026PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397000PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000539812PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000287820PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397010PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000309576PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397015PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397012PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397026PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397000PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000539812PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000287820PAX8chr2

113992971

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397010PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000309576PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397015PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397012PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397026PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000397000PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000539812PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000348715ENST00000287820PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397010PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000309576PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397015PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397012PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397026PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000397000PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000539812PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000397647ENST00000287820PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397010PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000309576PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397015PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397012PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397026PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000397000PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000539812PAX8chr2

113994178

-PPARGchr3

12421203

+
intron-5UTRENST00000263335ENST00000287820PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397010PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000309576PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397015PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397012PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397026PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000397000PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000539812PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000429538ENST00000287820PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397010PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000309576PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397015PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397012PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397026PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000397000PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000539812PAX8chr2

113994178

-PPARGchr3

12421203

+
5CDS-5UTRENST00000263334ENST00000287820PAX8chr2

113994178

-PPARGchr3

12421203

+

Top

FusionProtFeatures for PAX8_PPARG


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PAX8

Q06710

PPARG

P37231

Transcription factor for the thyroid-specific expressionof the genes exclusively expressed in the thyroid cell type,maintaining the functional differentiation of such cells.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for PAX8_PPARG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for PAX8_PPARG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PAX8NKX2-1, POU2AF1, CHUK, CXCL9, PKM, SERINC1, ANXA7, EP300, RB1PPARGNCOA4, GADD45G, DNTTIP2, PPARGC1A, HDAC3, HDAC4, RB1, EP300, EDF1, FABP1, NR0B2, SVIL, NRIP1, POU1F1, CREBBP, RXRA, MED24, MSX2, PML, ZBTB5, NR2E3, MAFF, ZBTB20, ZBTB3, ZNF496, ZBTB9, ZSCAN1, PIAS1, NCOR1, NCOR2, HMGA1, SP1, TFAP2A, CEBPB, MED1, ZNHIT3, TRIP4, JMJD1C, NFKBIB, SERPINH1, NCOA1, TRIM24, NCOA2, NCOA3, GRIP1, KAT5, LRIF1, HDAC1, MECP2, EZH2, NCOA6, NR0B1, COPS5, FHOD1, KIF1A, RXRB, ROBO4, KLF4, KDM4C, TNP1, KCTD13, RAD54L2, ANP32A, APP, RELA, UBC, CDC34, JAZF1, MED14, BCAS2, NEDD4, SMARCD3, SMARCA4, CDK5, MIF4GD, USP7, ALOX15B, SMAD2, ZFYVE9, NR3C1, MUC1, NSD1, PAXIP1, ASH2L, RBBP5, PRKAA1, PRKAA2, CTNNB1, SFPQ, NR4A1, NR4A2, JUN, NFE2L3, PHB2, STAT5A, VDR, RXRG, MAP2K1, CAV1, SMAD3, PDIA2, PPM1B, XRCC6, XRCC5, MAPK1, RANBP3, XPO1, JUND, LMO4, RFX5, CIITA, TCF4, NFKB1, PPARG, PRKCA, PIN1, STAT6, IKBKB, KAT2A, KIF11, CEP350, UBE2I, KLF5, IGFBP3, EGFR, MDM2, YWHAB, YWHAG, PPARGC1B, STAT1, STUB1, FLYWCH2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for PAX8_PPARG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgenePPARGP37231DB00244MesalazinePeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB00573FenoprofenPeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB00795SulfasalazinePeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB01039FenofibratePeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB01050IbuprofenPeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB13873Fenofibric acidPeroxisome proliferator-activated receptor gammasmall moleculeapproved
TgenePPARGP37231DB00313Valproic AcidPeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB00328IndomethacinPeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB00412RosiglitazonePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB00731NateglinidePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB00912RepaglinidePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB00966TelmisartanPeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01014BalsalazidePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01067GlipizidePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01118AmiodaronePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01132PioglitazonePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01252MitiglinidePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB01393BezafibratePeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB08604TriclosanPeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational
TgenePPARGP37231DB09213DexibuprofenPeroxisome proliferator-activated receptor gammasmall moleculeapproved|investigational

Top

RelatedDiseases for PAX8_PPARG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePAX8C1869118HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS3CTD_human;ORPHANET;UNIPROT
HgenePAX8C0009404Colorectal Neoplasms1CTD_human
HgenePAX8C2931367Thyroid cancer, follicular1CTD_human
TgenePPARGC0011860Diabetes Mellitus, Non-Insulin-Dependent5CTD_human
TgenePPARGC0011853Diabetes Mellitus, Experimental3CTD_human
TgenePPARGC0020538Hypertensive disease3CTD_human;HPO
TgenePPARGC0021655Insulin Resistance3CTD_human;HPO
TgenePPARGC0035126Reperfusion Injury3CTD_human
TgenePPARGC2609414Acute kidney injury3CTD_human
TgenePPARGC0002395Alzheimer's Disease2CTD_human
TgenePPARGC0021368Inflammation2CTD_human
TgenePPARGC0022116Ischemia2CTD_human
TgenePPARGC0028754Obesity2CTD_human;HPO;UNIPROT
TgenePPARGC0030297Pancreatic Neoplasm2CTD_human
TgenePPARGC0038356Stomach Neoplasms2CTD_human
TgenePPARGC1720861Familial Partial Lipodystrophy, Type 32ORPHANET;UNIPROT
TgenePPARGC0001418Adenocarcinoma1CTD_human
TgenePPARGC0004153Atherosclerosis1CTD_human
TgenePPARGC0004763Barrett Esophagus1CTD_human
TgenePPARGC0009375Colonic Neoplasms1CTD_human
TgenePPARGC0009404Colorectal Neoplasms1CTD_human
TgenePPARGC0010346Crohn Disease1CTD_human
TgenePPARGC0011849Diabetes Mellitus1CTD_human;HPO
TgenePPARGC0017658Glomerulonephritis1CTD_human
TgenePPARGC0018801Heart failure1CTD_human
TgenePPARGC0023794Lipoidosis1CTD_human
TgenePPARGC0023903Liver neoplasms1CTD_human
TgenePPARGC0025202melanoma1CTD_human
TgenePPARGC0025517Metabolic Diseases1CTD_human
TgenePPARGC0027746Nerve Degeneration1CTD_human
TgenePPARGC0029408Degenerative polyarthritis1CTD_human
TgenePPARGC0033860Psoriasis1CTD_human
TgenePPARGC0036341Schizophrenia1PSYGENET
TgenePPARGC0040136Thyroid Neoplasm1CTD_human
TgenePPARGC0079772T-Cell Lymphoma1CTD_human
TgenePPARGC0085413Polycystic Kidney, Autosomal Dominant1CTD_human
TgenePPARGC0221406Pituitary-dependent Cushing's disease1CTD_human
TgenePPARGC0236811Chronobiology Disorders1CTD_human
TgenePPARGC0242339Dyslipidemias1CTD_human
TgenePPARGC0242488Acute Lung Injury1CTD_human
TgenePPARGC0271694Familial partial lipodystrophy1CTD_human
TgenePPARGC0282548Leukostasis1CTD_human
TgenePPARGC0525045Mood Disorders1PSYGENET
TgenePPARGC2239176Liver carcinoma1CTD_human
TgenePPARGC2931367Thyroid cancer, follicular1CTD_human