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Fusion gene ID: 25618 |
FusionGeneSummary for OTUB1_RPS6KA4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OTUB1_RPS6KA4 | Fusion gene ID: 25618 | Hgene | Tgene | Gene symbol | OTUB1 | RPS6KA4 | Gene ID | 55611 | 8986 |
| Gene name | OTU deubiquitinase, ubiquitin aldehyde binding 1 | ribosomal protein S6 kinase A4 | |
| Synonyms | HSPC263|OTB1|OTU1 | MSK2|RSK-B|S6K-alpha-4 | |
| Cytomap | 11q13.1 | 11q13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ubiquitin thioesterase OTUB1OTU domain, ubiquitin aldehyde binding 1OTU domain-containing ubiquitin aldehyde-binding protein 1OTU-domain Ubal-binding 1deubiquitinating enzyme OTUB1otubain-1ubiquitin-specific protease otubain 1ubiquitin-specific-pro | ribosomal protein S6 kinase alpha-490 kDa ribosomal protein S6 kinase 4mitogen- and stress-activated protein kinase 2nuclear mitogen- and stress-activated protein kinase 2ribosomal protein S6 kinase, 90kDa, polypeptide 4ribosomal protein kinase B | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96FW1 | O75676 | |
| Ensembl transtripts involved in fusion gene | ENST00000541478, ENST00000535715, ENST00000422031, ENST00000428192, ENST00000538426, ENST00000543004, ENST00000536443, ENST00000543988, | ENST00000528057, ENST00000334205, ENST00000294261, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 2 X 1 X 2=4 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: OTUB1 [Title/Abstract] AND RPS6KA4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | OTUB1 | GO:0006974 | cellular response to DNA damage stimulus | 20725033 |
| Hgene | OTUB1 | GO:0071108 | protein K48-linked deubiquitination | 18954305|19211026|23827681 |
| Hgene | OTUB1 | GO:1901315 | negative regulation of histone H2A K63-linked ubiquitination | 20725033 |
| Tgene | RPS6KA4 | GO:0006355 | regulation of transcription, DNA-templated | 9792677 |
| Tgene | RPS6KA4 | GO:0006468 | protein phosphorylation | 9792677 |
| Tgene | RPS6KA4 | GO:0035556 | intracellular signal transduction | 9792677 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | HNSC | TCGA-CV-5973-01A | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000541478 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| intron-3CDS | ENST00000541478 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| intron-3CDS | ENST00000541478 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000535715 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000535715 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000535715 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000422031 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000422031 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000422031 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000428192 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000428192 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000428192 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000538426 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000538426 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000538426 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543004 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543004 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543004 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| 3UTR-3CDS | ENST00000536443 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| 3UTR-3CDS | ENST00000536443 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| 3UTR-3CDS | ENST00000536443 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543988 | ENST00000528057 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543988 | ENST00000334205 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
| In-frame | ENST00000543988 | ENST00000294261 | OTUB1 | chr11 | 63756224 | + | RPS6KA4 | chr11 | 64132773 | + |
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FusionProtFeatures for OTUB1_RPS6KA4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| OTUB1 | RPS6KA4 |
| Hydrolase that can specifically remove 'Lys-48'-linkedconjugated ubiquitin from proteins and plays an importantregulatory role at the level of protein turnover by preventingdegradation. Regulator of T-cell anergy, a phenomenon that occurswhen T-cells are rendered unresponsive to antigen rechallenge andno longer respond to their cognate antigen. Acts via itsinteraction with RNF128/GRAIL, a crucial inductor of CD4 T-cellanergy. Isoform 1 destabilizes RNF128, leading to prevent anergy.In contrast, isoform 2 stabilizes RNF128 and promotes anergy.Surprisingly, it regulates RNF128-mediated ubiquitination, butdoes not deubiquitinate polyubiquitinated RNF128. Deubiquitinatesestrogen receptor alpha (ESR1). Mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains, but not 'Lys-63'-linkedpolyubiquitin chains. Not able to cleave di-ubiquitin. Alsocapable of removing NEDD8 from NEDD8 conjugates, but with a muchlower preference compared to 'Lys-48'-linked ubiquitin. Plays a key non-catalytic role in DNA repair regulationby inhibiting activity of RNF168, an E3 ubiquitin-protein ligasethat promotes accumulation of 'Lys-63'-linked histone H2A and H2AXat DNA damage sites. Inhibits RNF168 independently of ubiquitinthioesterase activity by binding and inhibiting UBE2N/UBC13, theE2 partner of RNF168, thereby limiting spreading of 'Lys-63'-linked histone H2A and H2AX marks. Inhibition occurs by binding tofree ubiquitin: free ubiquitin acts as an allosteric regulatorthat increases affinity for UBE2N/UBC13 and disrupts interactionwith UBE2V1. The OTUB1-UBE2N/UBC13-free ubiquitin complex adopts aconfiguration that mimics a cleaved 'Lys48'-linked di-ubiquitinchain. | Serine/threonine-protein kinase that is required for themitogen or stress-induced phosphorylation of the transcriptionfactors CREB1 and ATF1 and for the regulation of the transcriptionfactor RELA, and that contributes to gene activation by histonephosphorylation and functions in the regulation of inflammatorygenes. Phosphorylates CREB1 and ATF1 in response to mitogenic orstress stimuli such as UV-C irradiation, epidermal growth factor(EGF) and anisomycin. Plays an essential role in the control ofRELA transcriptional activity in response to TNF. Phosphorylates'Ser-10' of histone H3 in response to mitogenics, stress stimuliand EGF, which results in the transcriptional activation ofseveral immediate early genes, including proto-oncogenes c-fos/FOSand c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3.Mediates the mitogen- and stress-induced phosphorylation of highmobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-likereceptor TLR4 to limit the production of pro-inflammatorycytokines. Functions probably by inducing transcription of the MAPkinase phosphatase DUSP1 and the anti-inflammatory cytokineinterleukin 10 (IL10), via CREB1 and ATF1 transcription factors.{ECO:0000269|PubMed:11035004, ECO:0000269|PubMed:12773393,ECO:0000269|PubMed:9792677}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for OTUB1_RPS6KA4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_537aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQYELDLREPA LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEA SQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLG VILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLR >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_544aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYE LDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKR HFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDES CDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSA RSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPL >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_296aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTV DPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPA >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_574aa MCGVEGCCQGGATRRGSLPGGRQLATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLE LSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNN AVMTDGLEAPGAGDRPGRAAVARSAMMQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNL HEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRP QSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKE LVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSAT >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_581aa MCGVEGCCQGGATRRGSLPGGRQLATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLE LSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNN AVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQS HPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDF GFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQG VSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRK >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_333aa MCGVEGCCQGGATRRGSLPGGRQLATRKRSVVRRCLKMAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLE LSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNN AAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFN >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_537aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQYELDLREPA LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEA SQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLG VILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLR >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_544aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYE LDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKR HFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDES CDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSA RSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPL >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_296aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTV DPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPA >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_537aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQYELDLREPA LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEA SQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLG VILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLR >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_544aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYE LDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKR HFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDES CDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSA RSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPL >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_296aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFR PQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTV DPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPA >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_546aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEDMTDPCLLQIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALA ARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQ YELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRK KRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYD ESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDG SARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANG >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_553aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEDMTDPCLLQIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALA ARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQ DSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGE LLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPEL LAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRG SSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKG >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_305aa MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEDMTDPCLLQIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALA ARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAAEIMCKIREGRFSLDGEAWQGVSEEAK ELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSA >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_507aa MAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPP PGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRL EANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENI LYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMC KIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREG >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_514aa MAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPP PGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAV KILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHR DLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQS QAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAF >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_266aa MAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPP PGDPRIFQGYSFVAPSILFDHNNAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1611nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCG CTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTG GAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAG CTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCA AGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATC CTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATG CAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGC GTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGC AAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACC GTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGG ACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGC TTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCT >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1632nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAG CTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTC AAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTG CACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGG CACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGC GACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCG CAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCC TGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGC CAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAG CTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCG CGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTC AACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACC GCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTG >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_888nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAA ATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTG GACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACG CCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTC TTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCA >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1722nt ATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCG GTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGT CTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAG CTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGG AAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTAC TCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAAC GCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAG CTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTC AAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTG CACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGG CACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGC GACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCG CAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCC TGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGC CAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAG CTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCG CGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTC AACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACC GCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTG >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1743nt ATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCG GTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGT CTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAG CTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGG AAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTAC TCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAAC GCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCG CCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAG AGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCA CACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTG GAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAG GAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTC GGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCG CAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCC TCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGT GTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCG TGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTC AACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAG CAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCC >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_999nt ATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCG GTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGT CTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAG CTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGG AAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTAC TCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAAC GCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTG GTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGC TCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAAC CGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCC TCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCC >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1611nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCG CTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTG GAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAG CTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCA AGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATC CTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATG CAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGC GTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGC AAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACC GTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGG ACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGC TTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCT >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1632nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAG CTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTC AAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTG CACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGG CACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGC GACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCG CAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCC TGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGC CAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAG CTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCG CGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTC AACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACC GCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTG >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_888nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAA ATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTG GACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACG CCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTC TTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCA >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1611nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCG CTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTG GAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAG CTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCA AGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATC CTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATG CAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGC GTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGC AAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACC GTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGG ACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGC TTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCT >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1632nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAG CTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTC AAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTG CACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGG CACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGC GACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCG CAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCC TGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGC CAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAG CTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCG CGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTC AACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACC GCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTG >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_888nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAA ATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTG GACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACG CCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTC TTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCA >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1638nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGG CTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCT GCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCT GTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCAC AACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAG TACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTC GCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTG AATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAG AAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTG CACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTG CGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGAC GAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGG CAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCC AAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGC AGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATG GCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGC GCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGC >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1659nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGG CTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCT GCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCT GTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCAC AACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAG GACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAG CGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGC CAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAG CTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATG CACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATC GACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTG CTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAG GGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGG CAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGC AGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCG GGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGG CGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGG >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_915nt ATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATC ATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGG CTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCT GCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCT GTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCAC AACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAG GAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGC GCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCA TTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCC ACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCC >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_1521nt ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCG CTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTG GAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAG CTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCA AGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATC CTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATG CAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGC GTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGC AAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACC GTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGG ACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGC TTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCT >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_1542nt ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTG GAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAG CTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTC AAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTG CACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGG CACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGC GACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCG CAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCC TGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGC CAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAG CTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCG CGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTC AACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACC GCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTG >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_798nt ATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAG TATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGG CCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCA CCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAA ATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTG GACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACG CCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTC TTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2798nt GTCAGATGCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTC ACTTTTCTACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCA CCGGGAACTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGTGCGGATCTGGGGCGGCCGGCCTCTCCTACAGGTC TCAGGTCCGCAGGCCTGGCGTGCCAGCACCTGCCACGGGACTGGAAGCCCATTCCTTGACAACGCCTAAGGGGATCCCGTTGCTAGGGCT GTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAA AGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCA TCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGG AGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCC GGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCC CACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGC TGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTG CGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGC TGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACC AGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAG CAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACA TCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCA TGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGG GCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGT GCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGA CCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCC GGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGG GCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCC CTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCAC CACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAG GGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATA GAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCA GGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTG TTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTG TTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAG GAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCC TTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCTGTGCCTTTGACTTTAAAATAAAAGTCCACCCAGTGCTGT >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2819nt GTCAGATGCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTC ACTTTTCTACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCA CCGGGAACTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGTGCGGATCTGGGGCGGCCGGCCTCTCCTACAGGTC TCAGGTCCGCAGGCCTGGCGTGCCAGCACCTGCCACGGGACTGGAAGCCCATTCCTTGACAACGCCTAAGGGGATCCCGTTGCTAGGGCT GTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAA AGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCA TCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGG AGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCC GGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCC CACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGC TGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACG AGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAG TCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATC TGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGC GGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACC GCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGC CGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGT CCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGA GCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGG AGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCG CGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCAT TCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCA CCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCC TGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCT GCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAA TTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCT TCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCT AAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAAT TACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGC TTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTA CTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCTGTGCCTTTGACTTTAAAA >In-frame_OTUB1_ENST00000535715_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_2074nt GTCAGATGCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTC ACTTTTCTACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCA CCGGGAACTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGTGCGGATCTGGGGCGGCCGGCCTCTCCTACAGGTC TCAGGTCCGCAGGCCTGGCGTGCCAGCACCTGCCACGGGACTGGAAGCCCATTCCTTGACAACGCCTAAGGGGATCCCGTTGCTAGGGCT GTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGGGAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAA AGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCA TCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGG AGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCC GGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCC CACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCA AAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCG TGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGA CGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCT TCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTG CACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCAC TGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGA CTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAG TTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGG GGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTC TCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTG GGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAA GGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTG GGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCTGTGCCTTTGACTTTAAAATAAAAGTCCACCCAGTGCTGTGTG >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2669nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAG CGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCC GCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCC TGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCG GGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCT TCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAA TCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCG AGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCT TCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGG CCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGC GGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGC GCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCA AGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCA AAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGG AGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGA CAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTT TGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTT CTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTC AACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGA AGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTC TCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAG >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2690nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAG CGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCT TTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGC GCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGG TCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCA GCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACA CGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCA CGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGA TGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGC GCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGC GGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCG AGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCG TGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGG GCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCC TCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTC CTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGG GGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAG GAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCG TTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAG AGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTC CTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGG >In-frame_OTUB1_ENST00000422031_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_1945nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCT GGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGG GCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCT CGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGC GGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAG GGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGC CCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAG AGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGG GGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTA AGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAAC TGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGC ATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCA CCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCC >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2669nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAG CGGTGGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCC GCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCC TGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCG GGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCT TCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAA TCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCG AGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCT TCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGG CCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGC GGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGC GCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCA AGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCA AAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGG AGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGA CAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTT TGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTT CTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTC AACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGA AGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTC TCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAG >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2690nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAG CGGTGGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCT TTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGC GCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGG TCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCA GCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACA CGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCA CGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGA TGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGC GCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGC GGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCG AGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCG TGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGG GCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCC TCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTC CTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGG GGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAG GAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCG TTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAG AGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTC CTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGG >In-frame_OTUB1_ENST00000428192_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_1945nt GCTGCTCCGCACTGCAGCTATGGTCGCATGCAGTGCCTGCCGAAGCCCGCAGCAGGAATGCTGCCTTCGGTGATTTTAATTTCACTTTTC TACTTCTCTCAATAACAAAATCCGCGTTTCAAACTCCAGGGAAAAGAAAACGGAATTGGCTCCAGGAGGATCTGCAATCACCACCGGGAA CTTTGGGAGGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGGCTGTTGCCAAGGCGGGGCAACGAGGAGGGGCTCGCTTCCGG GAGGACGGCAATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGC CGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTG TGCAGAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCA AGGGCCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTG CGGAGGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTG TGGCACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCT GGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGG GCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCT CGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGC GGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAG GGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGC CCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAG AGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGG GGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTA AGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAAC TGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGC ATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCA CCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCC >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2390nt AATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCA GCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACC CTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCG ATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAAT TCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCT CCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCA GGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCC AGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGT CACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGC TGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACG AGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACT TCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGG CGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGG CCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGG GTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCT CGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTC TCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGA AGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCC CCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCT CACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGA AGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCC CTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACT GAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCAC TTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCT GCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACC CCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAG >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2411nt AATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCA GCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACC CTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCG ATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAAT TCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCT CCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCA GGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGT GTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGG CTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGC TGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGT CGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGG CCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGT ACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGG GGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCC TTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGC TCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTG GGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATG CACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCC CCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGG CTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCAC CCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTG GGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCC CCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGA GGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGG GGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAG GAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGG >In-frame_OTUB1_ENST00000538426_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_1666nt AATTGGCAACCCGGAAGCGGTCGGTAGTGCGGCGCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCA GCGACTCCGAAGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCAGAACC CTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCG ATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAAT TCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCT CCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTG TATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGT GGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCA ACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGC AGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCC GCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCAC TCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGT ATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTC TCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAG TTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTT ATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCC TCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCT TCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCT >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2384nt GCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATG ATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGG TGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGG TGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTC GGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTC TCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCG CTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCG GCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTGCCAGTCACACC CCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGC ACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCATGCACGAGGAGG CGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCATCGACTTCGGGT TCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCTGCTGGCGCAGC AGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTG GCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTAT CCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGC TGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACG CCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGA AGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCC GAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCC CGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGTATT TTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCC CAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTA GGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATG GACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCA CTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCC TCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCTGTG >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2405nt GCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATG ATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGG TGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGG TGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTC GGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTC TCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGTGGCCAGGAGCG CTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCC GCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCC TGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGC GGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCG TGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGG TGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTG CCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGG TCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACG GGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGG GACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCG CAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCC TGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCG CCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGA CCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACT CCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGT GGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCC CCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCA CCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACC CTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCC ATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTG >In-frame_OTUB1_ENST00000543004_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_1660nt GCTGTTTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGAGCCGCTGGGCAGCGACTCCGAAGGTGTTAACTGTCTGGCCTATG ATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGGACATGACAGATCCCTGCCTCCTCCAGATTGCTGTGCAGAACCCTCTGG TGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGGCCTCGATTGGG TGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGAGGAATTCACTC GGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGCACCCTCCATTC TCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCG AGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGC AGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCA CCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGC TGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAG CCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGG AGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCAGAAGTATTTTT ATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAG GACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGA GTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTCACTTTATGGAC TGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTT TATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCT TTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCCAGGCTGTGCCT >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000528057_chr11_64132773_+_2485nt CCTTGCAGTCAGGCAGAGAGGCCTACGCCAGGGCCGAGCCCCCCGGCCTGCTCCAGCGGCGGCCCGCGCCGTGAGGGCCTCGAGTTTCGC TGGGCTACGGAGCACAAAGGTCCGGGCGGGCCATTCGGGATGTCGTAGGCGGCCCTGGGATGTGAGGGGCCTGCGGGATCTGTCCCTGAG GCCTGCGACTTTTTCTGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCA GAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGG CCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGA GGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGC ACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGT GGCCAGGAGCGCTATGATGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTCTGTGTGTCGCCGCTGCCGCCA GCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGAAGTGGCTGCCCTGCGCCTGTG CCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCTGGAGCTGCTGCGGGGCGGGGA GCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCTCGTGTCGGCCGTGAGCTTCAT GCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCCCGGGGCCCCGGTGAAAATCAT CGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCTGCAGTACGCTGCCCCCGAGCT GCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCTGTCGGGGCAGGTCCCCTTCCA GGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTG GCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGG CAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTC GGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCG GCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGG GGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCC CGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGA GCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGG GGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAA GCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACT GTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCA TTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCAC CCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCA >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000334205_chr11_64132773_+_2506nt CCTTGCAGTCAGGCAGAGAGGCCTACGCCAGGGCCGAGCCCCCCGGCCTGCTCCAGCGGCGGCCCGCGCCGTGAGGGCCTCGAGTTTCGC TGGGCTACGGAGCACAAAGGTCCGGGCGGGCCATTCGGGATGTCGTAGGCGGCCCTGGGATGTGAGGGGCCTGCGGGATCTGTCCCTGAG GCCTGCGACTTTTTCTGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCA GAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGG CCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGA GGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGC ACCCTCCATTCTCTTTGACCACAACAACGCGGTGATGACCGATGGGCTGGAAGCGCCTGGTGCTGGAGACCGGCCAGGTCGGGCAGCGGT GGCCAGGAGCGCTATGATGCAGGACTCGCCCTTCTTCCAGCAGTACGAGCTGGACCTGCGGGAGCCTGCGCTGGGCCAGGGCAGCTTTTC TGTGTGTCGCCGCTGCCGCCAGCGCCAGAGCGGCCAGGAGTTCGCAGTCAAGATCCTCAGTCGCAGGCTGGAGGCGAACACGCAGCGCGA AGTGGCTGCCCTGCGCCTGTGCCAGTCACACCCCAACGTGGTGAATCTGCACGAGGTGCATCACGACCAGCTGCACACGTACCTGGTCCT GGAGCTGCTGCGGGGCGGGGAGCTGCTGGAGCACATCCGCAAGAAGCGGCACTTCAGCGAGTCGGAAGCAAGCCAGATCCTGCGCAGCCT CGTGTCGGCCGTGAGCTTCATGCACGAGGAGGCGGGCGTGGTGCACCGCGACCTCAAGCCGGAGAACATCCTGTACGCCGACGACACGCC CGGGGCCCCGGTGAAAATCATCGACTTCGGGTTCGCGCGGTTGCGGCCGCAGAGTCCCGGGGTGCCCATGCAGACGCCCTGCTTCACGCT GCAGTACGCTGCCCCCGAGCTGCTGGCGCAGCAGGGCTACGACGAGTCCTGCGACCTCTGGAGCCTGGGCGTCATTCTGTACATGATGCT GTCGGGGCAGGTCCCCTTCCAGGGGGCCTCTGGCCAGGGCGGGCAGAGCCAGGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTT CTCCCTTGACGGGGAGGCCTGGCAGGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCT GAAGCTCGAGGGACTGCGGGGCAGCTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTC CTCTGGGCCCGCAGTGCGCTCGGGTCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGA GAATGCACCCCTGGCCAAGCGGCGGAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCG AGCCCCCGTCGCCTCCAAAGGGGCCCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCAT AGGGGCTGTGACCTGGGAGCCCGGCTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTAC CCCACCCCACTCCCAGACAGAGCAGAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCC TGCTGGGGAGTGGGGTTTGGGGGGCCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAA GAGCCCCTCCCCCACTTCTAAGCACTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCC TGGGAGGGGCACCCCTCAACTGTCACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGC CCTGGGGGACCCTCTGAAGCATTTCTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAA AAGAGGAGGCCATCTTCTCACCCACCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATC >In-frame_OTUB1_ENST00000543988_chr11_63756224_+_RPS6KA4_ENST00000294261_chr11_64132773_+_1761nt CCTTGCAGTCAGGCAGAGAGGCCTACGCCAGGGCCGAGCCCCCCGGCCTGCTCCAGCGGCGGCCCGCGCCGTGAGGGCCTCGAGTTTCGC TGGGCTACGGAGCACAAAGGTCCGGGCGGGCCATTCGGGATGTCGTAGGCGGCCCTGGGATGTGAGGGGCCTGCGGGATCTGTCCCTGAG GCCTGCGACTTTTTCTGGTGTTAACTGTCTGGCCTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAAGAGATTGCTGTGCA GAACCCTCTGGTGTCAGAGCGGCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATGACAACATCTATCAACAGAAGATCAAGGG CCTCGATTGGGTGGCTCTGGCTGCCAGGAAGATTCCAGCCCCATTCCGGCCCCAAATCCGCTCAGAGCTGGATGTGGGCAACTTTGCGGA GGAATTCACTCGGCTGGAGCCTGTCTACTCACCCCCTGGCAGCCCCCCACCTGGGGACCCCCGAATCTTTCAGGGATACTCCTTTGTGGC ACCCTCCATTCTCTTTGACCACAACAACGCGGCCGAGATCATGTGCAAAATCCGCGAGGGGCGCTTCTCCCTTGACGGGGAGGCCTGGCA GGGTGTATCCGAGGAAGCCAAGGAGCTGGTCCGAGGGCTCCTGACCGTGGACCCCGCCAAGCGGCTGAAGCTCGAGGGACTGCGGGGCAG CTCGTGGCTGCAGGACGGCAGCGCGCGCTCCTCGCCCCCGCTCCGGACGCCCGACGTGCTCGAGTCCTCTGGGCCCGCAGTGCGCTCGGG TCTCAACGCCACCTTCATGGCATTCAACCGGGGCAAGCGGGAGGGCTTCTTCCTGAAGAGCGTGGAGAATGCACCCCTGGCCAAGCGGCG GAAGCAGAAGCTGCGGAGCGCCACCGCCTCCCGCCGGGGCTCCCCTGCACCAGCCAACCCGGGCCGAGCCCCCGTCGCCTCCAAAGGGGC CCCCCGCCGAGCCAACGGCCCCCTGCCCCCCTCCTAATCCCCACCACTGTGACCCCCTTCCCTCATAGGGGCTGTGACCTGGGAGCCCGG CTCACTCCCGGAGGCCTCTGCCTGCGGCTGACCTGATCCCCAAGGGACTGTCCTTTCCTCTCCTACCCCACCCCACTCCCAGACAGAGCA GAAGTATTTTTATAAGCAGAGAATTTTTTATGTCTTACCAGATAGAGTTGCAGGGAAGGGGGGGCCTGCTGGGGAGTGGGGTTTGGGGGG CCCTCTCCCAGGACACTGCCTCTTCTGGGCAGAAGGCCCCTCCAGGGGGACTGCTCCAACAGGAAAGAGCCCCTCCCCCACTTCTAAGCA CTGAGTTAGGAGTGCTAACTCCTAAACTGGGACCCCCTACCCTGTTCTCCCCTGAGGCCCCGTTCCTGGGAGGGGCACCCCTCAACTGTC ACTTTATGGACTGTCTGTGCAATTACGTCCACCAAAGACCCGTGTTGGGGGTACTGAAGGAGAGGCCCTGGGGGACCCTCTGAAGCATTT CTGCCTCACTTTATGTCATCTGCTTCTCCCCTGTTGGGGCTAAGGAAGGAGATAGGTGGCTCCTAAAAGAGGAGGCCATCTTCTCACCCA CCCCTTCCTCTTTGGCACAGCTACTCCTGGCTGGGGGTGGGGCCTTGGGGGTCTGGGCTGGGCATCCATGGTCACTGCCTCAGCCCAGCC |
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FusionGenePPI for OTUB1_RPS6KA4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| OTUB1 | RNF128, USP8, DDX5, GNB2L1, NPM1, EBNA1BP2, EIF4A3, DDX54, DDX23, PCNA, NAT10, DDX24, FUS, MSH2, UBE2D2, UBE2N, STAMBP, CASP14, CPNE7, OTUD6B, STAMBPL1, UBC, RHOA, TRAF3, TRAF6, MAVS, ESR1, TP53, UBE2D1, H2AFX, ANXA1, CDKN1A, TTR, ANXA7, TSC22D1, UBE2S, UBE2V2, RFFL, PJA1, TRIM63, TRIM55, TRIM54, USP21, USP15, USP28, DSTN, ECT2, RNF126, ACTB, SMAD9, BIRC2, BIRC3, TNFSF12, SMAD2, SMAD3, SMAD4, KDM1A, NMRAL1, ERN1, UBE2D3, UBE2D4, RNF2, NEDD8, NFKBIA, CYP1A1, CSNK2A1, ACVR1, BMPR1A, ACVR1B, TGFBR1, BMPR1B, SERBP1, VPS29, NTRK1, EWSR1, FOXM1, AURKA, HIF1AN, MAZ, RCC1, CCNB1, SRPRB, YTHDF2, LUC7L2, NOSIP, NUDC, RPL26L1, MAGED2, STUB1, ZBTB21, SLC25A13, CHORDC1, RCC2, QPCTL, FARSB, TOMM22, OSGEP, MCCC2, UBTD1, CXorf56, ILKAP, C19orf43, DNAJC7, UBE2E2, USMG5, ZC3HAV1L, KCTD12, FAM136A, UBE2W, UBE2E3, CKAP2, C2orf47, SNRNP27, RP9, ABCF1, PNKD, NUP93, ABCF2, SLC27A4, UBL4A, AGK, HSD17B12, IMMT, TCEB1, PCBP1, PPA1, KARS, NOLC1, LAGE3, PIN1, AIMP2, TARDBP, PRDX1, CALD1, SLC25A11, SLC25A3, UBE2L3, UBE2G2, SEC61B, MTPN, CSE1L, SLC16A1, SLC25A1, UBE2E1, SSR4, SRP9, GCLM, BAG6, CRKL, RANBP1, TXLNA, HSPA9, GPX4, ATP5C1, BSG, CBS, HSPA4, PRDX2, DNAJA1, SDHA, PRDX5, ERP29, MPG, MAPK1, CAD, RRM1, TCEA1, SDHB, CTPS1, HSPA6, CBR1, HSPA8, HSPA5, TXN, ASNS, SLC3A2, HSPA1A, UQCRH, SLC25A5, COL1A1, AIFM1, BAG2, TDP2, UTS2, IKBKAP, CTNND1, IDH3B, ASNA1, PHGDH, PFAS, IRS4, NDUFA4, PGRMC1, SLIT3, FLYWCH2, RFX7, PFN2, CSRP2, VDAC3, MAP4, ADSL, EPM2A, ARCN1, PRSS38, SSH3, ZNF746, DUSP13, DUSP8, USP47, FGB, DLD, HSD17B10, IL1RL2 | RPS6KA4 | MAPK14, MAPK3, CREB1, FOS, NEDD4, MAPK1, SH3KBP1, DDX42, HECW2, RNF2, MYLK2, DLG3, MESDC2, CDC37, KLHDC3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for OTUB1_RPS6KA4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for OTUB1_RPS6KA4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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