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Fusion gene ID: 25591 |
FusionGeneSummary for OSCP1_NF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OSCP1_NF1 | Fusion gene ID: 25591 | Hgene | Tgene | Gene symbol | OSCP1 | NF1 | Gene ID | 127700 | 4763 |
| Gene name | organic solute carrier partner 1 | neurofibromin 1 | |
| Synonyms | C1orf102|NOR1 | NFNS|VRNF|WSS | |
| Cytomap | 1p34.3 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein OSCP1organic solute carrier protein 1organic solute transport protein 1oxidored nitro domain containing proteinoxidored-nitro domain-containing protein 1 | neurofibrominneurofibromatosis 1neurofibromatosis-related protein NF-1truncated neurofibromin 1 | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q8WVF1 | P21359 | |
| Ensembl transtripts involved in fusion gene | ENST00000495222, ENST00000235532, ENST00000356637, ENST00000433045, ENST00000315643, ENST00000354267, | ENST00000356175, ENST00000358273, ENST00000431387, ENST00000581113, ENST00000417592, ENST00000444181, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 15 X 13 X 12=2340 |
| # samples | 4 | 16 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/2340*10)=-3.8703647195834 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: OSCP1 [Title/Abstract] AND NF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NF1 | GO:0043547 | positive regulation of GTPase activity | 2121371 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | MESO | TCGA-UD-AAC4-01A | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000495222 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-3CDS | ENST00000495222 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000495222 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000495222 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000495222 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000495222 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000235532 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000235532 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000235532 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000235532 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000235532 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000235532 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000356637 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000356637 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000356637 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000356637 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000356637 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000356637 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-3CDS | ENST00000433045 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-3CDS | ENST00000433045 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000433045 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000433045 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000433045 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| intron-intron | ENST00000433045 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000315643 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000315643 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000315643 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000315643 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000315643 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000315643 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000354267 | ENST00000356175 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| In-frame | ENST00000354267 | ENST00000358273 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000354267 | ENST00000431387 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000354267 | ENST00000581113 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000354267 | ENST00000417592 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
| 5CDS-intron | ENST00000354267 | ENST00000444181 | OSCP1 | chr1 | 36915859 | - | NF1 | chr17 | 29701031 | + |
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FusionProtFeatures for OSCP1_NF1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| OSCP1 | NF1 |
| May be involved in drug clearance in the placenta.{ECO:0000269|PubMed:16006562}. | Stimulates the GTPase activity of Ras. NF1 shows greateraffinity for Ras GAP, but lower specific activity. May be aregulator of Ras activity. {ECO:0000269|PubMed:2121371,ECO:0000269|PubMed:8417346}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for OSCP1_NF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_85aa >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_85aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_255nt ATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATC CCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_3859nt ATTGGGACGCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGT GCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGA CAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGC AAGCCAAGTGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAA AATCAACTTAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATA ATGAACCCATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTC TTCTACTTTTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCT CAATTGTAAGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTC CCTTCTTCATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGT ATGTTTAATCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAA AGCCACAGACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCA ATAATTACAGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCAT CCAAACTAGTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAAC CAAAACTATACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATC AGTGAACAAAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACAT TTAGGGTAGCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTG AATGTCTTTTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAA TCACTGTGAAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGG CATTGGAATTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATC TGGATGTTCCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAA TGGCTTTGAGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCA CAGCTAATTCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTT AATGTAAATAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATT TGCCAAAATAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAA ACTTTTGTTTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATT AGAACTGTGTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCT GGGGTAAGTTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTG TTGGTTTGGTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATAC TGATATTTCCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCT TTGAAATGCAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACT TCTGACTTTTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAA CACTTTTTTAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCT GTTAAAAATATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGT CCTGGATAATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGG CAAAGTGGCTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCT ATCCTGTGTCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTT TTGTTTTTTGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAA AAATTCATTCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTAT ATTTACTATACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAA AATTTGATTATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAA TTGTATATGATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGT ACGCCAGCAGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTC >In-frame_OSCP1_ENST00000235532_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_3859nt ATTGGGACGCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGT GCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGA CAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGC AAGCCAAGTGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAA AATCAACTTAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATA ATGAACCCATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTC TTCTACTTTTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCT CAATTGTAAGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTC CCTTCTTCATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGT ATGTTTAATCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAA AGCCACAGACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCA ATAATTACAGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCAT CCAAACTAGTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAAC CAAAACTATACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATC AGTGAACAAAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACAT TTAGGGTAGCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTG AATGTCTTTTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAA TCACTGTGAAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGG CATTGGAATTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATC TGGATGTTCCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAA TGGCTTTGAGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCA CAGCTAATTCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTT AATGTAAATAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATT TGCCAAAATAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAA ACTTTTGTTTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATT AGAACTGTGTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCT GGGGTAAGTTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTG TTGGTTTGGTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATAC TGATATTTCCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCT TTGAAATGCAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACT TCTGACTTTTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAA CACTTTTTTAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCT GTTAAAAATATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGT CCTGGATAATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGG CAAAGTGGCTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCT ATCCTGTGTCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTT TTGTTTTTTGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAA AAATTCATTCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTAT ATTTACTATACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAA AATTTGATTATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAA TTGTATATGATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGT ACGCCAGCAGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTC >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_3841nt GGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGCTACCGCTGCT CTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCCGCAAAGGAAT CGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAGTGCAGAAGCA AAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACTTAACATGGGC TCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCCATCCGGTTTG CCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTTTTGGCGTGTA TCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTAAGAGAGGATG AATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTCATCCTACAGA GTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAATCTTTTAGCT GTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAGACAAGGTACT TGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTACAGGAAAATAA GTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTAGTTTATTTTT TTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTATACTAAGTAT AGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACAAAGTGTTGAA AATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTAGCTGATATTT TTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTTTTAATCTTCC TCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTGAAAAGACTGG TCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAATTTTCATAGT AATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTTCCAATTTAGA ACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTGAGGGGGGAAA AAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAATTCAATAAATA ATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAATAAAATTGGT TTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAATAAGAGGAAA GAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGTTTTTAAACTA TTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGTGTTTAGAAAT AGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAGTTTCACAGTT TCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTGGTGCATATGA TAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTTCCATAAACGG GTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATGCAAAAATACC TTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTTTTGAGGAAAA TCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTTTAGTCTTCAT ACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAATATTATAAGT AATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATAATCTACCTGT TATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGGCTACAGCTCT GTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTGTCCTAGTTGG GGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTTTGTTTTTGTT TCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCATTCTTAGTGTC AGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTATACTGTAAAT ATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGATTATTCTCGTG TTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATATGATAACTTAC TGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGCAGGAAAAATA CTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATTTTCCTCCTTG >In-frame_OSCP1_ENST00000356637_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_3841nt GGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGCTACCGCTGCT CTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCCGCAAAGGAAT CGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAGTGCAGAAGCA AAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACTTAACATGGGC TCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCCATCCGGTTTG CCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTTTTGGCGTGTA TCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTAAGAGAGGATG AATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTCATCCTACAGA GTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAATCTTTTAGCT GTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAGACAAGGTACT TGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTACAGGAAAATAA GTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTAGTTTATTTTT TTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTATACTAAGTAT AGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACAAAGTGTTGAA AATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTAGCTGATATTT TTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTTTTAATCTTCC TCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTGAAAAGACTGG TCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAATTTTCATAGT AATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTTCCAATTTAGA ACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTGAGGGGGGAAA AAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAATTCAATAAATA ATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAATAAAATTGGT TTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAATAAGAGGAAA GAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGTTTTTAAACTA TTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGTGTTTAGAAAT AGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAGTTTCACAGTT TCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTGGTGCATATGA TAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTTCCATAAACGG GTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATGCAAAAATACC TTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTTTTGAGGAAAA TCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTTTAGTCTTCAT ACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAATATTATAAGT AATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATAATCTACCTGT TATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGGCTACAGCTCT GTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTGTCCTAGTTGG GGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTTTGTTTTTGTT TCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCATTCTTAGTGTC AGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTATACTGTAAAT ATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGATTATTCTCGTG TTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATATGATAACTTAC TGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGCAGGAAAAATA CTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATTTTCCTCCTTG >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_3893nt CTTCCCGTCACGGCGTTGCCCCAGCAACCGGACTATTGGGACGCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTT CACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCG ACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCC ACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAGTGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGA AGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACTTAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCC CCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCCATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCT AAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTTTTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAA GTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTAAGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAG CCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTCATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATAC AAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAATCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACC ATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAGACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGG ATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTACAGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAAC TATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTAGTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTA AAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTATACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCC TCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACAAAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCAT TAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTAGCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTG TATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTTTTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAA ACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTGAAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGA ATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAATTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTAC AAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTTCCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTC TACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTGAGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCT GTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAATTCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTT CACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAATAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAA TTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAATAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATT GTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGTTTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGAC AGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGTGTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCAC CATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAGTTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGAT AACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTGGTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAAT AAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTTCCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATG ATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATGCAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTA ACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTTTTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAA CCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTTTAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCA AGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAATATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTT AAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATAATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTT GCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGGCTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCA GGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTGTCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGT AGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTTTGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCAT GTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCATTCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGT AAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTATACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTA AAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGATTATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATC ATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATATGATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTT TGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGCAGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAAT CATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATTTTCCTCCTTGTGTATGTACTTCCCCCACCCCCCTTTTTTTAAGTAAAA >In-frame_OSCP1_ENST00000315643_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_3893nt CTTCCCGTCACGGCGTTGCCCCAGCAACCGGACTATTGGGACGCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTT CACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGCTACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCG ACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCCGCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCC ACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAGTGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGA AGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACTTAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCC CCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCCATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCT AAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTTTTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAA GTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTAAGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAG CCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTCATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATAC AAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAATCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACC ATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAGACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGG ATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTACAGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAAC TATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTAGTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTA AAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTATACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCC TCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACAAAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCAT TAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTAGCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTG TATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTTTTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAA ACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTGAAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGA ATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAATTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTAC AAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTTCCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTC TACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTGAGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCT GTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAATTCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTT CACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAATAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAA TTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAATAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATT GTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGTTTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGAC AGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGTGTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCAC CATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAGTTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGAT AACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTGGTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAAT AAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTTCCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATG ATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATGCAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTA ACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTTTTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAA CCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTTTAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCA AGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAATATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTT AAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATAATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTT GCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGGCTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCA GGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTGTCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGT AGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTTTGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCAT GTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCATTCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGT AAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTATACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTA AAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGATTATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATC ATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATATGATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTT TGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGCAGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAAT CATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATTTTCCTCCTTGTGTATGTACTTCCCCCACCCCCCTTTTTTTAAGTAAAA >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000356175_chr17_29701031_+_3851nt GCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGC TACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCC GCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAG TGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACT TAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCC ATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTT TTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTA AGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTC ATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAA TCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAG ACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTAC AGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTA GTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTA TACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACA AAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTA GCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTT TTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTG AAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAA TTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTT CCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTG AGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAAT TCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAA TAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAA TAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGT TTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGT GTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAG TTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTG GTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTT CCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATG CAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTT TTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTT TAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAA TATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATA ATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGG CTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTG TCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTT TGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCAT TCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTA TACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGAT TATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATAT GATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGC AGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATT >In-frame_OSCP1_ENST00000354267_chr1_36915859_-_NF1_ENST00000358273_chr17_29701031_+_3851nt GCTGCGGCCTGGCCTTCAGGCCACTGGCTACCGAACCCCGGGGCTCTTCACCAGTCCAGCTCGTTTCCAGCACCATGTCGGTGCGGACGC TACCGCTGCTCTTCTTGAACTTGGGCGGGGAGATGCTTTACATCCTCGACCAACGGCTGCGGGCCCAGAACATCCCGGGAGACAAGGCCC GCAAAGGAATCGACAAGGAGAACGTTGAACTCTCCCCTACCACTGGCCACTGTAACAGTGGACGAACTCGCCACGGATCCGCAAGCCAAG TGCAGAAGCAAAGAAGCGCTGGCAGTTTCAAACGTAATAGCATTAAGAAGATCGTGTGAAGCTTGCTTGCTTTCTTTTTTAAAATCAACT TAACATGGGCTCTTCACTAGTGACCCCTTCCCTGTCCTTGCCCTTTCCCCCCATGTTGTAATGCTGCACTTCCTGTTTTATAATGAACCC ATCCGGTTTGCCATGTTGCCAGATGATCAACTCTTCGAAGCCTTGCCTAAATTTAATGCTGCCTTTTCTTTAACTTTTTTTCTTCTACTT TTGGCGTGTATCTGGTATATGTAAGTGTTCAGAACAACTGCAAAGAAAGTGGGAGGTCAGGAAACTTTTAACTGAGAAATCTCAATTGTA AGAGAGGATGAATTCTTGAATACTGCTACTACTGGCCAGTGATGAAAGCCATTTGCACAGAGCTCTGCCTTCTGTGGTTTTCCCTTCTTC ATCCTACAGAGTAAAGTGTTAGTCCTATTTATACATTTTTCAAGATACAAGTTTATGAGAGAAATAGTATTATAACCCCAGTATGTTTAA TCTTTTAGCTGTGGACTTTTTTTTTAACCGTACAAAACTGAAAGAACCATAGAGGTCAAGCCTCAGTGACTTGACACCATAAAGCCACAG ACAAGGTACTTGGGGGGGAGGGCAGGGAAATTTCATATTTTATAGTGGATTCTTAAGAAATACTAACACTTGAGTATTAGCAATAATTAC AGGAAAATAAGTGCGACCACATATATCTTAACATTACTGAATTAAAACTATGGCTTCTAAGTCCTTATCCAAACTCAGTCATCCAAACTA GTTTATTTTTTTCTCCAGTTGATTATCTTTTAATTTTTAATTTTGCTAAAGGTGGTTTTTTTGTGTTTTGTTTTTTGTAAACCAAAACTA TACTAAGTATAGTAATTATATATATATATATATTTTTTCCCCTCCCCCTCTTCTTTCCTAACTAATTCTGAGCAGGGTAATCAGTGAACA AAGTGTTGAAAATTGTTCCCAGAAGGTAATTTTCATAGATGTTTGCATTAGCTCCATAGCAAAATGGAATGGTACGTGACATTTAGGGTA GCTGATATTTTTATTTTGTTAAATAATTTCCAAGAATAGAGTATGGTGTATATTATAAATTTCTTTGATAAGATGTATTTTGAATGTCTT TTAATCTTCCTCCTCCTCTCCAAAAAAATCAGAAACCTCTTTAAGAAAACATGTAGGTTATATATGCTAGAATTGCATTTAATCACTGTG AAAAGACTGGTCAGCCTGCATTAGTATGACAGTAGGGGGGCTGTTAGAATTGCTGCTATACTGGTGGTATGGATTATCATGGCATTGGAA TTTTCATAGTAATGCAGATCCAATTTCTTTGTGGTACCTGCAGTTTACAAAATAATTTGACTTCAGTGAGCATATTGGTATCTGGATGTT CCAATTTAGAACTAAACCATATTTATTACAAAAAGATATTAATCCCTCTACTCCCAGGTTCCCTTTATATGTTAAGATATAATGGCTTTG AGGGGGGAAAAAATAAACCTAGGGGAGAGGGGAGTTTCCTGTAGTGCTGTTTCATTAGAGGATTTCAGTAAATTAAATTCCACAGCTAAT TCAATAAATAATGGTACATTTAAGTGTTCTGATTTTAATAATATATTTCACATTTATCCACACAGTAACAATGTAATATGTTAATGTAAA TAAAATTGGTTTTGATACTCAGAAATAACAAGAATTTAATTTTTTAAATTTGTTTACAGTCCTGGGAAAAGTAAGAATTATTTGCCAAAA TAAGAGGAAAGAAAACCTTAGTATTATTAATGAGTTTACCATAGAATTGTTGGAAATACTGAAGACAGGTGCAATTTACTAAACTTTTGT TTTTAAACTATTGTAGAGGCTGCATTAGAAGAAAATGTTTATAATGACAGAGCAACTATGACTATATAAAAAAGCTGAAATTAGAACTGT GTTTAGAAATAGATCAGTAACCCAGTGCCAAGGATGCCAAGCTGCCACCATGGTCTTGGCTCTCCCACAACCCAGTGTTTCTGGGGTAAG TTTCACAGTTTCTAGGCCCTGGAATAGCAGGCAGTGTAAGCCTTTGATAACTTTAGTTCGATGTTTTTCTTGTTTTTGTTTGTTGGTTTG GTGCATATGATAGTGGGTGTTATGCTATTTTGCTCTTCCCATCAAAATAAAGAAACTTCCAGAGGTTTACTGTTAAAAATACTGATATTT CCATAAACGGGTTTACCAAGGGTGTAGTATTTCATACCGCCTGAAATGATCAGCATTGGCACAAATCAAAATTCAGCCGCCTTTGAAATG CAAAAATACCTTTGACTAGTAAGTACATCCTAGGAGTTTGAAAACTTAACTAAGGTTTAAAATTTACCTTGTTTAAAGAACTTCTGACTT TTGAGGAAAATCTAGCTTTCCAAGTAACTAAAATGTACATGAGATAAACCTCTCACCACTATGTGTCCCTTGAGAAATGCAACACTTTTT TAGTCTTCATACTTGTAATCTATAAAAGAAATTCTGAAGTTTAGACCAAGTTGCCCATTTCTGCGTAATTGACATAAGTTCTGTTAAAAA TATTATAAGTAATTCGTTTCGGTTTGTAGATGTTTCCCCTGACTTGTTAAAGAGGAAACCAGGAACTCAGTCATGTTTTTGTCCTGGATA ATCTACCTGTTATGCCAGTACTCCCATCCGAGGGGCATGCCCTTAGTTGCCCAGATGGAGATGCAGTTCAGTAGATTTGGGGCAAAGTGG CTACAGCTCTGTCTTCCATTCACTCAACACCTGTTCATGACTGAGCCAGGTGCCCAGGACACATCCTAAACAGTCAGCTTCTATCCTGTG TCCTAGTTGGGGAGACAGAGTGCCAGCCAGCAACCCTCCCAGGTTTGTAGGTTTTAGGGGTTTTCAGTTTTGTTTGGGTTTTTTGTTTTT TGTTTTTGTTTCTACATCCTTCCCCGACTCCCAGGCATAATGAGGCATGTCTTACTCAATGTTATGCAATGGATTTAGGCAAAAATTCAT TCTTAGTGTCAGCCACACAATTTTTTTTAATGCAGTATATTCACCTGTAAATAGTTTGTGTAAAATTTGACAAAAAAAGTATATTTACTA TACTGTAAATATATGTGATGATATATTGTATTATTTTGCTTTTTTGTAAAGCAGTTAGTTGCTGCACATGGATAACAACAAAAATTTGAT TATTCTCGTGTTAGTATTGTTAACTTCTTTTTGCGACTGCGTTACATCATTTAAAGAAAATGCTGTGTATTGTAAACTTAAATTGTATAT GATAACTTACTGTCCTTTCCATCCGGGCCTAAACTTTGGCAGTTCCTTTGTCTACAACCTTGTTAATACTGTAAACAGTTGTACGCCAGC AGGAAAAATACTGCCCAACAGACAAAATCGATCATTGTAGGGGAAAATCATAGAAATCCATTTCAGATCTTTATTGTTCCTCACCCCATT |
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FusionGenePPI for OSCP1_NF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| OSCP1 | WDR54, XPO1, GYG2, KANK4, DRG1 | NF1 | HRAS, SMARCA4, POLR2A, TIRAP, SIRT7, VCP, NSFL1C, CAV1, YWHAB, FAF2, NXF1, CCDC8, HLA-DPA1, EFNB2, CD274, TNFSF13B, CA14, SLAMF1, VSIG4, TGOLN2, HTR6, NOSIP, KRAS, CLK1, CDC5L, APP, YWHAH, PML, TRAF6, PTEN, SDC2, EGFR, CD79B, P4HA3, SCN3B, VSIG1, SIGLECL1, EPHA1, FAM174A, KCTD3, KIF13B, ZBTB21, KSR1, CGN, GIGYF1, LRFN1, RTKN, MAST3, DENND1A, SH3PXD2A, SRGAP2, DENND4C, PPM1H, EIF4E2, SIPA1L1, LIMA1, RALGPS2, MAGI1, CBY1, TESK2, CDC25C, DCLK1, GIGYF2, HDAC4, LPIN3, ZNF638, CAMSAP2, NADK, MAPKAP1, SRSF12, RASAL2, SYDE1, KIAA1804, TIAM1, AGAP1, CDC25B, CDK16, SH3RF3, PHLDB2, PLEKHA7, KIF1C, OSBPL6, FAM110B, USP21, NAV1, TANC2, PTPN13, FAM53C, ANKRD34A, STARD13, PTPN14, GAB2, DENND4A, INPP5E, TOP1, TOP2A, TOP3A, NRAS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for OSCP1_NF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for OSCP1_NF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | NF1 | C0027831 | Neurofibromatosis 1 | 34 | CTD_human;ORPHANET;UNIPROT |
| Tgene | NF1 | C2931482 | Neurofibromatosis-Noonan syndrome | 5 | CTD_human;ORPHANET;UNIPROT |
| Tgene | NF1 | C0349639 | Juvenile Myelomonocytic Leukemia | 3 | CTD_human;HPO;ORPHANET |
| Tgene | NF1 | C0004114 | Astrocytoma | 2 | CTD_human;HPO |
| Tgene | NF1 | C0023467 | Leukemia, Myelocytic, Acute | 2 | CTD_human |
| Tgene | NF1 | C0025202 | melanoma | 2 | CTD_human |
| Tgene | NF1 | C0206727 | Nerve Sheath Tumors | 2 | CTD_human |
| Tgene | NF1 | C0001430 | Adenoma | 1 | CTD_human |
| Tgene | NF1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Tgene | NF1 | C0016057 | Fibrosarcoma | 1 | CTD_human |
| Tgene | NF1 | C0017636 | Glioblastoma | 1 | CTD_human |
| Tgene | NF1 | C0017638 | Glioma | 1 | CTD_human |
| Tgene | NF1 | C0023186 | Learning Disorders | 1 | CTD_human |
| Tgene | NF1 | C0023827 | liposarcoma | 1 | CTD_human |
| Tgene | NF1 | C0027809 | Neurilemmoma | 1 | CTD_human |
| Tgene | NF1 | C0027830 | neurofibroma | 1 | CTD_human |
| Tgene | NF1 | C0027962 | Melanocytic nevus | 1 | CTD_human |
| Tgene | NF1 | C0031511 | Pheochromocytoma | 1 | CTD_human |
| Tgene | NF1 | C0162678 | Neurofibromatoses | 1 | CTD_human;HPO |
| Tgene | NF1 | C1261473 | Sarcoma | 1 | CTD_human |
| Tgene | NF1 | C1834235 | NEUROFIBROMATOSIS, FAMILIAL SPINAL | 1 | CTD_human;UNIPROT |
| Tgene | NF1 | C3714756 | Intellectual Disability | 1 | CTD_human;HPO |
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