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Fusion gene ID: 25408 |
FusionGeneSummary for OLFM2_CRTC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: OLFM2_CRTC1 | Fusion gene ID: 25408 | Hgene | Tgene | Gene symbol | OLFM2 | CRTC1 | Gene ID | 93145 | 23373 |
| Gene name | olfactomedin 2 | CREB regulated transcription coactivator 1 | |
| Synonyms | NOE2|NOELIN2|NOELIN2_V1|OlfC | MECT1|TORC-1|TORC1|WAMTP1 | |
| Cytomap | 19p13.2 | 19p13.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | noelin-2neuronal olfactomedin related ER localized protein 2 | CREB-regulated transcription coactivator 1mucoepidermoid carcinoma translocated protein 1transducer of regulated cAMP response element-binding protein (CREB) 1 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O95897 | Q6UUV9 | |
| Ensembl transtripts involved in fusion gene | ENST00000264833, ENST00000590841, | ENST00000321949, ENST00000338797, ENST00000594658, ENST00000601916, | |
| Fusion gene scores | * DoF score | 10 X 1 X 7=70 | 5 X 3 X 4=60 |
| # samples | 10 | 5 | |
| ** MAII score | log2(10/70*10)=0.514573172829758 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: OLFM2 [Title/Abstract] AND CRTC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | OLFM2 | GO:0009306 | protein secretion | 21228389 |
| Tgene | CRTC1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 14536081 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCS | TCGA-N9-A4Q3-01A | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264833 | ENST00000321949 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| In-frame | ENST00000264833 | ENST00000338797 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| In-frame | ENST00000264833 | ENST00000594658 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| In-frame | ENST00000264833 | ENST00000601916 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| intron-3CDS | ENST00000590841 | ENST00000321949 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| intron-3CDS | ENST00000590841 | ENST00000338797 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| intron-3CDS | ENST00000590841 | ENST00000594658 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
| intron-3CDS | ENST00000590841 | ENST00000601916 | OLFM2 | chr19 | 10046980 | - | CRTC1 | chr19 | 18853720 | + |
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FusionProtFeatures for OLFM2_CRTC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| OLFM2 | CRTC1 |
| Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expressionand translocation of OLFM2 to the nucleus where it binds to SRF,causing its dissociation from the transcriptional repressorHEY2/HERP1 and facilitating binding of SRF to target genes(PubMed:25298399). Plays a role in AMPAR complex organization (Bysimilarity). Is a regulator of vascular smooth-muscle cell (SMC)phenotypic switching, that acts by promoting RUNX2 and inhibitingMYOCD binding to SRF. SMC phenotypic switching is the processthrough which vascular SMCs undergo transition between a quiescentcontractile phenotype and a proliferative synthetic phenotype inresponse to pathological stimuli. SMC phenotypic plasticity isessential for vascular development and remodeling (By similarity).{ECO:0000250|UniProtKB:Q568Y7, ECO:0000250|UniProtKB:Q8BM13,ECO:0000269|PubMed:25298399}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CRTC1 | chr19:10046980 | chr19:18853720 | ENST00000321949 | + | 0 | 14 | 299_366 | 42 | 635 | Compositional bias | Note=Ser-rich |
| Tgene | >CRTC1 | chr19:10046980 | chr19:18853720 | ENST00000338797 | + | 0 | 15 | 299_366 | 42 | 651 | Compositional bias | Note=Ser-rich |
| Tgene | >CRTC1 | chr19:10046980 | chr19:18853720 | ENST00000321949 | + | 0 | 14 | 242_258 | 42 | 635 | Motif | Nuclear export signal |
| Tgene | >CRTC1 | chr19:10046980 | chr19:18853720 | ENST00000338797 | + | 0 | 15 | 242_258 | 42 | 651 | Motif | Nuclear export signal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >OLFM2 | chr19:10046980 | chr19:18853720 | ENST00000264833 | - | 1 | 6 | 136_193 | 21 | 455 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >OLFM2 | chr19:10046980 | chr19:18853720 | ENST00000264833 | - | 1 | 6 | 58_85 | 21 | 455 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >OLFM2 | chr19:10046980 | chr19:18853720 | ENST00000264833 | - | 1 | 6 | 194_446 | 21 | 455 | Domain | Olfactomedin-like |
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FusionGeneSequence for OLFM2_CRTC1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000321949_chr19_18853720_+_614aa MWPLTVPPPLLLLLCSGLAGQLQLQKSQYLQLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRL GSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSK QAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIG GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPP PPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG SSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNI >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000338797_chr19_18853720_+_630aa MWPLTVPPPLLLLLCSGLAGQLQLQKSQYLQLGPSRGQYYGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTT RHHGLVDRVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTV PGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSS SSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPP QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPA NQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLP DSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRLX >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000594658_chr19_18853720_+_614aa MWPLTVPPPLLLLLCSGLAGQLQLQKSQYLQLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRL GSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSK QAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIG GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPP PPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG SSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNI >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000601916_chr19_18853720_+_447aa MWPLTVPPPLLLLLCSGLAGQLQLQKSQYLQLGPSRGQYYGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRL GSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSK QAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIG GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSHGSLPDSQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000321949_chr19_18853720_+_1842nt ATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCC TACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCA CCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCC CCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCG CCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGG AGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTG TCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAG GCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATC ATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCC GACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCC >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000338797_chr19_18853720_+_1890nt ATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG CCCAGCGGATTTCTGGGGGAGGCCCTGGCAGCGGCTCCTGTCTCTCTGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACC CGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGA CGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTG CACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTC CCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCC TGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCC CTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCC AGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAG CACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATC ACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCG CAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGT GGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCC CCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCC AACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGG GACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATC AGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCG GACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAA GAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTG ACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGA >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000594658_chr19_18853720_+_1842nt ATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCC TACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCA CCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCC CCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCG CCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGG AGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTG TCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAG GCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATC ATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCC GACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCC >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000601916_chr19_18853720_+_1341nt ATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAGTACCTG CAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCCTTCCAG ACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTC GGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCC GCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGG TCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAG CAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAAC ACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCG CTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGT GGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGG CGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGC AGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAG CAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACC AGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000321949_chr19_18853720_+_2598nt CGCAACAAAGACTCGGAGCGAGCGAGGGGGCGGGGGTGGGGCGGAATCCCGGCCGCCGGCGAGGCGGGGGAGGCGGCGGCGCAGGGTCGC CCCGGCCGGGCGGGCGGGGTCGCGCCTGGTGGCGGTCCCCGCGCCGAGGCGCCGCTAGGGCGGGCGGGGGTCGGGACGCCGGGCTAGGGG CGCGTCATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAG TACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCC TTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGC CGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCA CCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGC AGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTT TCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAG GAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCG ACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGC ATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAG GCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAG CTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAG CCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAG CCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCC TCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCC CCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAAT GCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTAC TCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCC AACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTC GACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTT CTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCG CCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGC CAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGC TGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTG TAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCAT TTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAG >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000338797_chr19_18853720_+_6888nt CGCAACAAAGACTCGGAGCGAGCGAGGGGGCGGGGGTGGGGCGGAATCCCGGCCGCCGGCGAGGCGGGGGAGGCGGCGGCGCAGGGTCGC CCCGGCCGGGCGGGCGGGGTCGCGCCTGGTGGCGGTCCCCGCGCCGAGGCGCCGCTAGGGCGGGCGGGGGTCGGGACGCCGGGCTAGGGG CGCGTCATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAG TACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCC TTCCAGCCCAGCGGATTTCTGGGGGAGGCCCTGGCAGCGGCTCCTGTCTCTCTGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGG ACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAA CACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCC GCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTA ACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCC AAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGG GGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGC AGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCT CCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCA CCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCA CCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCC CCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAG TCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCC CCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTG TTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAAC GCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGC CTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTC TCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGAC CCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGC CTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAAC GGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGC GAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCC CTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCT CAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCC CGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCCAGAGCGCGGG GCAGACGCAAAGTGAAATAAACACTATTTTGACGGCTGTCTTTTATATTTCTGAGCACACACAGAGCCCTGGCGTCCACCGGGGCAGGCG CAAAGTGGACAGAGCATGCAGGGCGGCGGACCCCCCCACGACCCTCCTCGCCCTGTCTCCATCCCCTCGAAGCCCTGCCTCACCGCAGGC AGGCCCATCGGTGGCCACCTTTGCCGGGAAGTGACCGGAAGGCCCCGTGAGGGGTCGAACGCGGAGGCAGGGGTTACCTCTTGGGGCTTT ACAATCCGTGGCCCCTCCTGTCCTGCACTGTGGTCACCGGTCCTGTCATAGATGCTGTTAATTTAAGGTACAGGCAGAGGTGGCCAGGGG AGTTTCATTGTGGTTTTTTTTTCCTTTTAGTTTCTAGTTACATTTTGGTTGTAGATGACTCGCTTAATCTTTTAAGCCAACACTTGCCTG AGAGCATGTTTTTATTTCAGAAATCCAACTTTACCTATTTTTTAAGCTAACTGGAAATGGAGGCCATGCGCCCCAAAGCAGCCCGCCACC CACCTGAGTGTAAGAAGTGAGTCCGGCTTTTGGGTTTCACCCCAAGTTATCTCAAAACAAAAGGGCTGGTCAGGCTGGGCAGGGCCTTGT CAGGAGCTCACGGTAGGCAGAGGTGCCTCTGCCAGGGCCACAGAACAGACTTCCGGGAAGGGGCCTTGGCTTTTATTGAGGGTCTCTCAA AGACCCAGCCTGCCAGCCTCTCCCAGAGGTGCCTGCTAGTCCTTAGAGTGTGTGTGTGAAGATGCCATGACCAGTGGCAGCTGAGACCTC TCTGCCCCAAGAGTGTGGGGGACTGGCAGGGAGCGAGGGTCCCCGAGACGAGGACCACGGTCCTCCCTGAGAACCTGGGTGGAACTGGCA TTTCATCCCCTCTCCACCCTACCCTCTGGCTCCTAGCCCACACCCCCTCTCTTGGGCAGCGTGGTCTGCTGGCTGCCCCTTCTTGGCAGC TCAGGGTCGTGGCAGGTGGACTTGGAGACACACAGCAGTGTGTGTTTTAGTGGCAGGTTTCAGGAGCACCTCTAAGACCAGGGTGACAGG GTACTTGGGAGCTGTCCTGGACCCTCCCCATACCACGGGCCCTGCAAGGGAGGCATCAGGGCTGGCTTTGTTTTCTGCTGTTCTTGGAAT AGGAACTGCTGTTCTGATCCCCCCAAAACTGCATTGCGGCTCTCGCTCGCTCCTGCCTGCCGGGACAGCGCCTTCTGCTGAGTCCGTTTA TTTGTAGTGTCATGGCTGCTGCTTTCACTGGGGTCCTGGGCACCCTGGCTTCTGTCCTCAGAGCTGGGTTTGATCCTAGCAACCATCCCT TCCTCTCTTTGCCCGGCAATGCCTTTGGCATGTGTCTGAGCAGCCAAGTGGCCACTCATAGGAGAAGGCTCCCTGGTCACGTTGCTCCTG CTGCCGTCTTGTTCCAAGGTGCGGGGGGGACACTGTTGGTCTGTCCAGGTCAAGGTCCCTTTCTCTTACCATGACAGAGGCTGGGGGCAG ACAGCGGGGACTTTTTTTTTTTTTTAAGAAAAACTACATGTACATAGGAGAGTTTCATTACCATTAGACTTGTATGTAGGACTTAAAAAA AAATGGCCTTAATAAAATTACAAGCAACCCGCCTGGATGCGGTTTTCAAAAGAAGGCATTGAGGACCATGCTAGGAAACCTCATACCCCA TCCGTCCAACCTCCGGCGGGCGCCACTGCTTGTCCTCTGGTCTTCGGTGTGGACAGATAGGAGAGGAGGGATGCCCACCTCGGAGCATCC CAGGCCCGTGGCCCATTTTCAGCATCCTGAAGCCAGATTCACAGTGACATTGTGTTAACGTGACGACCTTGGTCCATTATGGAGTTCTTT TTCCAATAAGAACCTGGTGGACCGAGGTCCGAGCTTGCCAGGGACAGTGGGGCCCACGCGAGTACCCGGGGCCCAGCCAGGAGCCAGCAG CCAGGCGTCCCTGTGTTCCAGAAGGATTCACGCCCCTCCTGGACCTGGGCGGGCCTCCCAGGGGGTCTGTATCACGGCCTTTTGTGTGTG CGTACGTGTGGTTTTTTTAAATATCACTACTACATATTCTTGAATTGCCAAGACTTTCTGAAACAAGACAGCTTAAGGGAATCAGCCTTT TGCTTTGTGATGTGAAAATACTGTGATTTGACGAGCCGCTTCCTGAGGGGCAGGCCCACGTGGGGAGGTTGCGCCGTGTACATAGACCCG CCGTCTGTGTCCTTGGTCAGGCCCGGATGCTTGGTCTACACTGGGTTAGAGGCTGCTCTCCCCACGCACCCATGTGCTCATGGCTTCTGC AGACCCTCTGCTGGGTACATCGGTCCCCTACGGCGAAGTTCAGCCAGGGCTCTCCCTCCTGAGAGCATGGCGTCCCCACCTTCCTGTTTC GCCGACGTCACTACCCAGGGTGGCAAGTCTTGCAGGCAGAGGGTGTAGCCCAAGTTCAGCCTCTCTCTGTGTCCTCCAGAGAAGAGGGTT CTTTGCCCTCATCAGGGCCCTGCTTGTGGGTTTTCGGCTCTGGGGAGGAGAGTGTTGGCATCAGTGTGTTTGGCCTGATTTCTTCAGGGG GCCAAGCTCCCGGGAGGACCCCTAGCCAGGAGGGCCCCCCATGTCCATCCATCCCTCCTGCTGGGGCTTGGATGTCAGGCTTGGGGGCTG TGAGCTGGGACCTCGCCTGAGCCCGGTCAGGTGGGACAGGAGCCTGCCAGAAGCCCATGGGGGGCCAGGCCGGGTGGCTTCTATTTTATT TTTTTAGAGATGGGGTCTTGCTGTGTTGCCCAGGCTGGTCTCGGACTCCTGGGCTCAAGCAGTCCTCCCTCCTCGGCCTCCCAAAGTTCT GGGGCTACAGGTGTGAGCCACTTCTGCCCAGCATCCCAGGCCTGAACAGCCTTGGCAGGACCCGTCCCTAGAGGGGGCTCTGGTGCCTCC CTTAGGTGGGCCTTGAGCTGGTTTTTAACCAAACATCCTTCCAAACTCGGGCTGCGACCTGCTTCCTGAGTTTTCTGTATTTCCAAGGAG CCCTCCGACCAGGGAGAGGCTGGTGGAGTAAGGTCCAGCGGTATTCGGGGGTCCTCTGTCACCTCGCCCTGAAAACAGCAGCTCCCATCA CCTTCACTGGGTCCCGATGGAGCCGTCTCAGAGGCCGAGGGGCCCTCTGTGTGGGGGTGGGACGCAGGGGCTCTCAGAGCAAGGGCCACA AAGCCGATGGCACAGATGTGCCCCTGGGCCTGGCCCGTCACCCACATGTGGTGCCCTGGGCCAGGGCGTGCGGGCGCCAGAGCCTTCCCT ACACAGCCTAAGAGCAGGGGCAAGACTCGGCCCCTCACTCACCCTGGGAGGCCTGCCTGGGCTACATGGACACCTGGGTCTCTTTCTACC CCCATTCACCATGGACCAGGGGCCTCCATTTCCTGGGGGCTCTTGCGGCATGTGATTTGGGGGTCCCTGGGACATTCTCCCGTCAGCTCC ACCTGAGCCAAGTGTCCTGTTCCCTGCGGCCCTTGGCCTTCCAGGGTCCTGGCCAGGCAGGGGTCAGGCACCCCATACTCTTCCGTGTGG CACAGGTGTCCACCCACCCCCACTGGCCACAGACACCATTCTCCCCCTGGGAGCAGGAGGTGGAGTAAGTTGTACCCCCAGGCCTGGGTG CTGGGGAGTTCCTGAGGGCATGGGTGGGGCAGGAGTGAGTGCCTCGTGATCCCAGCCTCAGTTTCTCTCTTGTCACTTTCTCAAACCTGC AGGTCTCAGGGCCCCGGGCTCCTCCTGGGCAGGATGGGGGGCAGGGGCTGGGCCTTGGGGTGGTGCTGGCTCTGATGATTCCAGAGCCTG TATCCACCTTCTGGGCTCCTGGCCAGCACCCCACCCCCAGGAGCCAGGGACAGGTGGCATGTGTTGGGGTCGGGGGATGGCCCCCATCTC GAAGTGTTCTGGAATTTGGGGGCAACCCTTGCCCAGCCCAGCCATCAAGAACTTCTGATCTCCTGCCCACCAGGAGGGGACTTAGCCATG GACTTGGCCAGTAGGCCTGGGGAGGGAGGGCTTTGGCAGCCAAAGTCCACTGGCCCTGCCGTGCCCCTGAGTAGGAAACTGTCCCCTAGG GGCTGGGTGGCCCCACTGATATATGCAAACCCGCCGGTCCGAGCCCTGTTCCTGCCTGTGCTCCTCTGTGCCCAGGCTGGCTCTCCCCCA >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000594658_chr19_18853720_+_2598nt CGCAACAAAGACTCGGAGCGAGCGAGGGGGCGGGGGTGGGGCGGAATCCCGGCCGCCGGCGAGGCGGGGGAGGCGGCGGCGCAGGGTCGC CCCGGCCGGGCGGGCGGGGTCGCGCCTGGTGGCGGTCCCCGCGCCGAGGCGCCGCTAGGGCGGGCGGGGGTCGGGACGCCGGGCTAGGGG CGCGTCATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAG TACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCC TTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGC CGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCA CCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGC AGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTT TCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAG GAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCG ACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGC ATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAG GCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGGCTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAG CTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCCGCCTCCTCCACCCGCGTCCCAGCAG CCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTGACTCGTGGGCCACAG CCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACATCGCC TCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCC CCAGGGAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAAT GCTCTGTCCCACCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTAC TCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCC AACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTC GACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTT CTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCG CCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGC CAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGC TGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTG TAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCAT TTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAG >In-frame_OLFM2_ENST00000264833_chr19_10046980_-_CRTC1_ENST00000601916_chr19_18853720_+_2083nt CGCAACAAAGACTCGGAGCGAGCGAGGGGGCGGGGGTGGGGCGGAATCCCGGCCGCCGGCGAGGCGGGGGAGGCGGCGGCGCAGGGTCGC CCCGGCCGGGCGGGCGGGGTCGCGCCTGGTGGCGGTCCCCGCGCCGAGGCGCCGCTAGGGCGGGCGGGGGTCGGGACGCCGGGCTAGGGG CGCGTCATGTGGCCGCTCACGGTCCCGCCGCCGCTGCTGCTGCTGCTGTGCTCAGGCCTGGCCGGACAGCTCCAGCTCCAGAAATCCCAG TACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGATCGGGAGTGGCACCATGGACCTGCCC TTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTGTACCGGGAGCGTGGC CGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACCTCTCA CCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGC AGTGGGTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTT TCCAAGCAAGCATGGGACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAG GAAAACACTACAGCCCTGATCCCCGCCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCG ACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGCACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGC ATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCACAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAG GCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGCTGGAGCAGTTCAACATGATGGAGAACGCCATCAGC TCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGAC TCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCCCAGCCTCTCTAAAGAA CTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCCCTGACC CTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCG GGCACGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCT TGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCG AGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGG CTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGG GGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCC AGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCCAGAGCGCGGGGCAGACGCA |
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FusionGenePPI for OLFM2_CRTC1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| OLFM2 | SRSF5, ST13, BLOC1S6, KRTAP10-3, OLFM1, ZFHX4, RNF40, TUBB1, DVL2, FEM1B, OLFM3, KDM5C, MSTO1, LRIF1, ZSWIM8, CBY1, EGFL7, DTNB, SDF2L1, DPYSL4, METTL3, PEX6, GALNS, BMP7, ZNF507, C15orf39, FUT11, NCOR1, CTDNEP1, BANP, VCPIP1, USP54, GPATCH8, N4BP2L2, DNAJB9, HAUS8 | CRTC1 | CREB1, MAP3K1, MEIS1, YWHAE, CREBBP, EP300, SRPK2, XPO1, KCTD3, KIF13B, CBY1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for OLFM2_CRTC1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for OLFM2_CRTC1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CRTC1 | C0279628 | Adenocarcinoma Of Esophagus | 1 | CTD_human |
| Tgene | CRTC1 | C0525045 | Mood Disorders | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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