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Fusion gene ID: 25024 |
FusionGeneSummary for NTRK3_PEAK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NTRK3_PEAK1 | Fusion gene ID: 25024 | Hgene | Tgene | Gene symbol | NTRK3 | PEAK1 | Gene ID | 4916 | 79834 |
| Gene name | neurotrophic receptor tyrosine kinase 3 | pseudopodium enriched atypical kinase 1 | |
| Synonyms | GP145-TrkC|TRKC|gp145(trkC) | SGK269 | |
| Cytomap | 15q25.3 | 15q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | NT-3 growth factor receptorETS related protein-neurotrophic receptor tyrosine kinase fusion proteinETV6-NTRK3 fusionneurotrophic tyrosine kinase, receptor, type 3tyrosine kinase receptor C | pseudopodium-enriched atypical kinase 1NKF3 kinase family membersugen kinase 269tyrosine-protein kinase SgK269 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q16288 | Q9H792 | |
| Ensembl transtripts involved in fusion gene | ENST00000394480, ENST00000557856, ENST00000357724, ENST00000355254, ENST00000360948, ENST00000542733, ENST00000558676, ENST00000317501, ENST00000558306, ENST00000540489, | ENST00000560626, ENST00000558305, ENST00000567337, ENST00000312493, | |
| Fusion gene scores | * DoF score | 7 X 7 X 3=147 | 6 X 5 X 4=120 |
| # samples | 11 | 7 | |
| ** MAII score | log2(11/147*10)=-0.418312631311705 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NTRK3 [Title/Abstract] AND PEAK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NTRK3 | GO:0000187 | activation of MAPK activity | 23027130 |
| Hgene | NTRK3 | GO:0001933 | negative regulation of protein phosphorylation | 23027130 |
| Hgene | NTRK3 | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 23027130 |
| Hgene | NTRK3 | GO:0008284 | positive regulation of cell proliferation | 23027130 |
| Hgene | NTRK3 | GO:0010628 | positive regulation of gene expression | 23027130 |
| Hgene | NTRK3 | GO:0030335 | positive regulation of cell migration | 23027130 |
| Hgene | NTRK3 | GO:0032148 | activation of protein kinase B activity | 23027130 |
| Hgene | NTRK3 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation | 23027130 |
| Hgene | NTRK3 | GO:0050927 | positive regulation of positive chemotaxis | 23027130 |
| Hgene | NTRK3 | GO:0090630 | activation of GTPase activity | 23027130 |
| Hgene | NTRK3 | GO:2000251 | positive regulation of actin cytoskeleton reorganization | 23027130 |
| Tgene | PEAK1 | GO:0016477 | cell migration | 20534451 |
| Tgene | PEAK1 | GO:0034446 | substrate adhesion-dependent cell spreading | 20534451 |
| Tgene | PEAK1 | GO:0046777 | protein autophosphorylation | 20534451 |
| Tgene | PEAK1 | GO:0051893 | regulation of focal adhesion assembly | 23105102 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-TM-A7CF-01A | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000394480 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000394480 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000394480 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000394480 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| In-frame | ENST00000557856 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000557856 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000557856 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000557856 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| Frame-shift | ENST00000357724 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000357724 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000357724 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000357724 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| Frame-shift | ENST00000355254 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000355254 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000355254 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000355254 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| Frame-shift | ENST00000360948 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000360948 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000360948 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000360948 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| Frame-shift | ENST00000542733 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000542733 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000542733 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000542733 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| In-frame | ENST00000558676 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000558676 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000558676 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000558676 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| Frame-shift | ENST00000317501 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000317501 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000317501 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000317501 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| intron-3CDS | ENST00000558306 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| intron-intron | ENST00000558306 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| intron-intron | ENST00000558306 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| intron-intron | ENST00000558306 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| In-frame | ENST00000540489 | ENST00000560626 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000540489 | ENST00000558305 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000540489 | ENST00000567337 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
| 5CDS-intron | ENST00000540489 | ENST00000312493 | NTRK3 | chr15 | 88726649 | - | PEAK1 | chr15 | 77407661 | - |
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FusionProtFeatures for NTRK3_PEAK1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NTRK3 | PEAK1 |
| Receptor tyrosine kinase involved in nervous system andprobably heart development. Upon binding of its ligandNTF3/neurotrophin-3, NTRK3 autophosphorylates and activatesdifferent signaling pathways, including the phosphatidylinositol3-kinase/AKT and the MAPK pathways, that control cell survival anddifferentiation. {ECO:0000269|PubMed:25196463}. | Probable catalytically inactive kinase. Scaffoldingprotein that regulates the cytoskeleton to control cell spreadingand migration by modulating focal adhesion dynamics(PubMed:23105102, PubMed:20534451). Acts as a scaffold formediating EGFR signaling (PubMed:23846654).{ECO:0000269|PubMed:20534451, ECO:0000269|PubMed:23105102,ECO:0000269|PubMed:23846654}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NTRK3_PEAK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NTRK3_ENST00000557856_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_519aa MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRS LHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYISVRAKLKNLSSIITAWLSGRVWLSILTFSRTVVISLLKSLTVCFPGRI QMTLKRMRMTWKRLKKTPKEKRMGKTQSPVLKQHHPRKRIRESXARSRGATLWSSPGRFHVLLWLILCETLWPSMGKALICMRGRCVCCS YSYALVLSTSNPTMSLTAIYAXRTCYLSTTSLGGLPKALGLQSPAPPHLIPLGLXXATSLRPSRRAIWWTPRSSGTSLALPQRSXQLPSI KSVMSSRQASSSMRCCTYPTPLMRTQSXRRGNTHEQTCLASHSAPPTPGVCSSWPAASXIPTLLSGSSFQTPKASSSVCSGAPAKISSRL >In-frame_NTRK3_ENST00000558676_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_519aa MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRS LHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYISVRAKLKNLSSIITAWLSGRVWLSILTFSRTVVISLLKSLTVCFPGRI QMTLKRMRMTWKRLKKTPKEKRMGKTQSPVLKQHHPRKRIRESXARSRGATLWSSPGRFHVLLWLILCETLWPSMGKALICMRGRCVCCS YSYALVLSTSNPTMSLTAIYAXRTCYLSTTSLGGLPKALGLQSPAPPHLIPLGLXXATSLRPSRRAIWWTPRSSGTSLALPQRSXQLPSI KSVMSSRQASSSMRCCTYPTPLMRTQSXRRGNTHEQTCLASHSAPPTPGVCSSWPAASXIPTLLSGSSFQTPKASSSVCSGAPAKISSRL >In-frame_NTRK3_ENST00000540489_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_519aa MDVSLCPAKCSFWRIFLLGSVWLDYVGSVLACPANCVCSKTEINCRRPDDGNLFPLLEGQDSGNSNGNASINITDISRNITSIHIENWRS LHTLNAVDMELYTGLQKLTIKNSGLRSIQPRAFAKNPHLRYISVRAKLKNLSSIITAWLSGRVWLSILTFSRTVVISLLKSLTVCFPGRI QMTLKRMRMTWKRLKKTPKEKRMGKTQSPVLKQHHPRKRIRESXARSRGATLWSSPGRFHVLLWLILCETLWPSMGKALICMRGRCVCCS YSYALVLSTSNPTMSLTAIYAXRTCYLSTTSLGGLPKALGLQSPAPPHLIPLGLXXATSLRPSRRAIWWTPRSSGTSLALPQRSXQLPSI KSVMSSRQASSSMRCCTYPTPLMRTQSXRRGNTHEQTCLASHSAPPTPGVCSSWPAASXIPTLLSGSSFQTPKASSSVCSGAPAKISSRL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NTRK3_ENST00000557856_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_1559nt ATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGGCTGGACTATGTGGGCTCCGTGCTG GCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGAACCTCTTCCCCCTCCTGGAAGGGCAG GATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTTCCATACACATAGAGAACTGGCGCAGT CTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGAACTCAGGACTTCGGAGCATTCAGCCC AGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCAGCAGTATTATCACAGCTTGGCTGTCC GGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCCTAACCGTCTGCTTCCCTGGGAGGATC CAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAACGGATGGGAAAAACCCAAAGCCCTGTT CTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGTTGTGGTCATCACCAGGGAGGTTCCAT GTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTATGAGAGGCAGGTGTGTCTGCTGCTCT TACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCTAGAGAACCTGCTACTTGTCCACTACC AGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCACTAGGCTTATAGTGAGCAACTTCTCTC AGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCCAGAGATCATAACAGCTACCCAGTATA AAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTTTGATGAGAACCCAGAGCTGAAGGAGA GGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCAGCAGCTGGCCAGCTGCCTCCTGAATC CCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGGCCCCCGCGAAGATCTCTTCCAGACTT TCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCGAACACTGCTCATGATCAAGTTTGCTG AGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGCTTTTGCCACTACAGACTCCCTCAGTT >In-frame_NTRK3_ENST00000558676_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_1559nt ATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGGCTGGACTATGTGGGCTCCGTGCTG GCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGAACCTCTTCCCCCTCCTGGAAGGGCAG GATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTTCCATACACATAGAGAACTGGCGCAGT CTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGAACTCAGGACTTCGGAGCATTCAGCCC AGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCAGCAGTATTATCACAGCTTGGCTGTCC GGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCCTAACCGTCTGCTTCCCTGGGAGGATC CAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAACGGATGGGAAAAACCCAAAGCCCTGTT CTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGTTGTGGTCATCACCAGGGAGGTTCCAT GTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTATGAGAGGCAGGTGTGTCTGCTGCTCT TACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCTAGAGAACCTGCTACTTGTCCACTACC AGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCACTAGGCTTATAGTGAGCAACTTCTCTC AGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCCAGAGATCATAACAGCTACCCAGTATA AAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTTTGATGAGAACCCAGAGCTGAAGGAGA GGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCAGCAGCTGGCCAGCTGCCTCCTGAATC CCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGGCCCCCGCGAAGATCTCTTCCAGACTT TCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCGAACACTGCTCATGATCAAGTTTGCTG AGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGCTTTTGCCACTACAGACTCCCTCAGTT >In-frame_NTRK3_ENST00000540489_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_1559nt ATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGGCTGGACTATGTGGGCTCCGTGCTG GCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGAACCTCTTCCCCCTCCTGGAAGGGCAG GATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTTCCATACACATAGAGAACTGGCGCAGT CTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGAACTCAGGACTTCGGAGCATTCAGCCC AGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCAGCAGTATTATCACAGCTTGGCTGTCC GGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCCTAACCGTCTGCTTCCCTGGGAGGATC CAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAACGGATGGGAAAAACCCAAAGCCCTGTT CTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGTTGTGGTCATCACCAGGGAGGTTCCAT GTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTATGAGAGGCAGGTGTGTCTGCTGCTCT TACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCTAGAGAACCTGCTACTTGTCCACTACC AGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCACTAGGCTTATAGTGAGCAACTTCTCTC AGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCCAGAGATCATAACAGCTACCCAGTATA AAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTTTGATGAGAACCCAGAGCTGAAGGAGA GGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCAGCAGCTGGCCAGCTGCCTCCTGAATC CCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGGCCCCCGCGAAGATCTCTTCCAGACTT TCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCGAACACTGCTCATGATCAAGTTTGCTG AGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGCTTTTGCCACTACAGACTCCCTCAGTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NTRK3_ENST00000557856_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_7581nt CTTTTTTAGAAGCAGCGATCGGAGATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGG CTGGACTATGTGGGCTCCGTGCTGGCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGAAC CTCTTCCCCCTCCTGGAAGGGCAGGATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTTCC ATACACATAGAGAACTGGCGCAGTCTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGAAC TCAGGACTTCGGAGCATTCAGCCCAGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCAGC AGTATTATCACAGCTTGGCTGTCCGGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCCTA ACCGTCTGCTTCCCTGGGAGGATCCAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAACGG ATGGGAAAAACCCAAAGCCCTGTTCTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGTTG TGGTCATCACCAGGGAGGTTCCATGTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTATG AGAGGCAGGTGTGTCTGCTGCTCTTACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCTAG AGAACCTGCTACTTGTCCACTACCAGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCACTA GGCTTATAGTGAGCAACTTCTCTCAGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCCAG AGATCATAACAGCTACCCAGTATAAAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTTTG ATGAGAACCCAGAGCTGAAGGAGAGGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCAGC AGCTGGCCAGCTGCCTCCTGAATCCCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGGCC CCCGCGAAGATCTCTTCCAGACTTTCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCGAA CACTGCTCATGATCAAGTTTGCTGAGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGCTT TTGCCACTACAGACTCCCTCAGTTGTATTGTGAAAATTCTGCAGCACCGTTAATGTGTACCTGGATGATGCTTTTACTACATCTTCACCT TCTTCATGTCACCCATGCACTTCCCCTCCCTAGTGCTCACTCCAAATTCAAGGAAAGAAGAAAGGCAAACCTCTATCCCTGTCCGTGAAC AAGTGGGTCTATTCAGAAAGGTTATCCACTGCCCCAGATTGAATGAGAAGCTGAGTCTGTCTTAACTTTACAGAAATTCAGCTGCACAAA CTTGCAGTTGCCTTCCCTTGAAACACCTTCTATCCTAATAGTCCCATAAATGCAGGTAAAAATGAAAATCCATATTCTTGAAGGGACAGC TTCTTTGGTATGAACTCAGCCAGTGAGCTGTGTCCATTTCCTCCATAATTCTGGATATCACCTATCTTTTTAGCACCAAGTATTTATTCT CACTAGCAGTAGACAGACTTAACCAGTCTCTACCACGACCCAGTAGACTCTGACAACAGACTCTTCCTTTAAGGTGTCAACAACTGACTT ACTAGGCAGGACTGCCATCCTTAGCATCAGCCCAGTTTTGGTTACCAGGGACTATATCTTTTGTTCCAGGAGAGAGTAGAAAGAAAAGGA GAGATCCCATCCTTGGGTCATAGACCCATTTTCATTGCCATTATCTGTAAGTATGTGCACTGCATGGAGGACAGCCCTAATAGTCTCCCC TCTGCTGCCACTGCCTGATTCTCCACTCTGTCCCCACTTGCCAGTGAAGTTTGGATTTATCAGCCACTTGTGGCCCATTACAGAGCTGAC CCAAGGTGGTGTCACCAATGCCTCAGCAGGGTGGAGTGCAGTTCAGAGCTTATAAATAGCTGGCAGGGCATGAGGAGATGATTTTCTTGC ATGTGCAATTCTCTAGGGGCCATCAGGAAACAGAGTTTAAAGTACCCTTTGATTACTGTCAGAACTGTCAGCATTTGCAGTTTTCCCCGA GCAGTAATTGGCCAGCTCCCTTCTATCAGTAGCCAGTGTTAACTAGTTTACCAAATGCTGTAAACAATTGCCCTGAATGAAATAGCTGTC AGTGGAGCTCTAAGATCTCCTTTAGAGGGCACAGTGAGGTGGGCTGTTGGGATGGCCGTAGGCAGGGGAGAGGAAGAAGGCCACTGATGA GACTGCTGACCTCCTCAGAAGGTTGACCTCTTCTAGAGAGACTGCCTCCCAGTGTTTAAGTGGCTCATTGCTCCTTCTGACTCTGTAAAA TGGCTCTGGAGGACAGCTCACAGGAATTCTGATTGCTGAGGTGGGTGATTGAGAGCTGTTCACCATGTGTGCAGCCTGTGCTCCCCTTCT ATGGATATGTGTGCAATTTTTGTATGTATTTTTTTAGCTGTATATTACAGTGTTTATGTTGCAACTTCACCTGAAGCGAGTCTACAGAAA CCCTCCCCCTTCTTCCCTTGGCACATATTTGCGCTAAGAGATGAGCGTTCCTTCCACTGGGGTTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTATGTATACACATGTTCACCTGTGCTTGTTTTATTCAAAACTGTGAGTATGTGTTTACTTTGACCTTGAAATC CCAAGAGTCACTCGAACAATGTGTGTGTACACTTGTGTGCCCATGTGTGCGTGCACACGCATGCTGGAAGTAGAGGCCAGGCCTCTAGAA AAGCAACCTGTGGCAGGGTTGACAGACATGTTCTCTGTGCCTAGTGAGTGAGTGAGCCCTGAGGCCCCTCATCTACCAGTGCAGAGTTTC CTTAAAGCCAAGACTGACTGTGCAGTATTACTTACATAGCACATTAGTGGCCTTGGAAATTTCTAAACTTTTAACATTTTTAACAGCTTT TCATGTGATTCATGTATAACAAAGAGGATCAGGAAAGGAAAATAATGTATTTTATTGTGCTCTTATTACTTTTTTAAGTGATTGTAATAT GTGAGGCTCTATTTGGAGAATGTCCCTTATCCCCTGGCCAGCAATATAGGACTCACAGGAAAGAAGGCTGGTTAGCCCACAAAGAGTCTT GCCTCCTCTAGCCAGAGTGCAGGGCTCTGCTCCTAGGAATGGCCATGGAGTGGGCATGCTGCTGCAGGCCAGCAGTCTGCTCTTGGTGTC CTGTGGCATGGCCGCGCCTTGCCTTGAAGGTTGGTGTTTGGTTCATCTTAGCATAGAACATGTGCACATAACTCCTTGCCTGATTATGCA CTGAAGGGCAGCACACAGACCACTGACCATGTCAGCCAGCACATTCCCTTAACCTCCCCCACCTCCCATCTTGCAATGTCTTGCATATTG AGATATACCTTCTCAATGTCATGTTCGTGGTGCCTTGCCCATGTAAATTTCAATGTTGACTATTTAATGAGGTTACATATTTAATGCTGA ATGTTTCCTGGTCCCTCTATTTGTTATGTCTCTACTTATCTTTTTTTTTCTTTCTCTTTTTCTGTTATGATTTGGATCCAGTCTTCACTT TAACTCTATGGTATAATAAGCATGGACACCTCCACTACCATTATCTTACAGCACTGGTAAACCAAGCACCTCTTCATATCAGATGTTTTT AGTACTGTTTTTATATTCAGATTTGTTAAGGGCAAAAGATGAATGCAAACTAGCCAGAGAAAAGCCTCAGGCTTCCCAGAGACAGGTGGC TAGATTAATTTTTCTCTGGGTGATGGCCAAAGAATGTGAGATAGAGAGGGAAGGGGGTGTTACAGGTTAGAGCAGAATAGAGAAAGAAAC TATATTTCTAGGCAAAAAGTACTACATGAGTTGGTCTTCAGAATATTTTTCCAAAAAAATGAAATTCAGTCAGTTTAACATTATCACAAA TATTTTTCATTTTAATTGTGGTAGGACCTTTGAATTTGTTCATCAACTGGAAAGAAATCCTACCCTCTGTAGACACATACACACACATTT ATATATCTATGTGTTTGAATTGTGACTAGTATAGCACTTTACATTTTCTCAAGTAACAGGAAGTTATTGCCTTCAATATTGATTGGAAAT TGTTTTCTATTGAAGTCTATACTGTAGAGTTTTCCATTTATATTGAGAGTTTGAACAATTAAGCTCCTATTGGAACTTTTCCTTAAGCCA CATGAGCATGAACAATCTCTGTGACACTTGGGTGCTAGAGAAACACAACAGTGGCTAAAGTAGCCAAGAGCAAGACTGAATGTATAGCAG AGTGCCTTGTTAGAGTGGTAACCTAGTCTTGGAAGCAATTCAGTGGATGTTTCATAAAGAGGACTAGAACTTCAAGAAGCCTCCTGTGCT GGCTGAGGTGAGCCCTTTTGGTATATGTACACTACTGGGTTGCCTAGAAGCCAATTCATGAAGAATAACAGCAGGATGAGAAAAAGAGTC ACTGTAACCTGTGGAACAACAACGTAAGAATCACCAACCCCTAGGCTGAGCTAGAACTGGAAGCCAGGAATATGGCAATGAGTTTCAAGA TTTGCCCTCAGAAGATGAACTGGGTGAGGTATGGGTTGAGGTGAGGGCACAAGCACTCATCCTACCTACCCTGCTGCTGTTGAGGAGCTA GAAGTAAAACATATTGGTTAGGATTTTAACAGTTGGAGTAGCCTCCCATTATCAGATTAAGTGGGGGTCACTTTTGCTTCCAAACTCAGA ATAAGTTTGTAAACATGGGAAAGTCTAAGCCAAGAGATCTAAAGCTCTAGAAATATTAATGACATTTCTGGGAGTAAAACTACTAAAAAT TATATCTTAAAAGTTTCTAGTAGTATGAAGTTCCCAGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGGCGAGGTG GGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCATCTCTACTAAAAATACAAAAATTAGCCGGGCA TGATGGCAGGCACCTGTAATCTAAGCTACTCGGGAGGCTGAGGCAAGAGAATCTCTTGAACCCAGGAGGCAAAGGTTGCAGTGAGCCAAG ATCACGCCATCGCACTCCAGCCTGGGAGATTGAGCAACTTCGTCTCAAAAAAAAGTTTCCAGGAAAGATCTTTGGGTCCTACTAAGCGTC TCAATTTTGAGTTATGAATACTTTGGTTCAGGGAAGTAACCTGACATTTGGTTTTGCTGGAATTAGGGTTTTCGCTAGATTTGACTGCAA TTAGGATTTCTTCTAGATTTTACCAGCAGTGATCTGAAAAAGTACAGGCTAGTCACAGAAATAGAGATGGATTTAGGATACTACACTATA TTTCAAATGATTCTAGATGTGTAAATATAGTATGAACATTCTTGGAGAGGGGTGAGACAAACTGGACTTGCTGGGCCAACCCTGGCATGT TTTTCATTCTCCTCACTAGTTGACAAGGATTGAAAATTCCGCTCCAGCCTAATGAGTGAACAGGATGGCTGCCCACAAAACCAAGTTATT AGCTTTATGTCATCGAAGCTCATATTCTCAAAGGCCCAAAGTGCTGTGCCGAGACAAATCCAAGTGCTGCTCTTGCTGAAGTGCGCACTG AAGTCCAGCTGTCCGTGCTTACAGCAGTGCCAAAAGTGGGGATTCCATGGACCAAAAACGGTGCCATAAGGGAAGCCAGAAGAGTTGCAG TGCAAGATCCTGGGAGAGATTATACCAAAGAAATCAAGCCTTTTTATCCTGATGCTTCTAAGATGATGAGGGTGAGCTGTGACAGATGCT GTGGGAGGGGAGTTCACATACATTCCATGTCAAGGCATTTAGCTGATAAATCCATCCTCAGAAAAGCACCTTTTTAAAAAGAAGTCCATT TTGTATATTAGAAGATGATGATGATGATGAAGATGAAGAAAGCCCTGGCAGATACAAAGTTCCTCAGTATTTAAGGAGAAGGATCTCTTC CATGTCCCCTTGACATGACTGTGGCTATTGCCCAAACCTCAGCTTGAGAACATCATATAATACTGAGAGCGGAAGATTTTTTTAAAGAGA TATGGTAGTTTAAATAGGTTTGTTTAAAGAACTCTTGGGAAATTTCTTAACAAATTGTAATTGTTTTTATAAACCTTCCTACAGAGTTGT GTACCATTCATCATCACCATCATTTAATATCTGTAAGTGCCCAGAAGGTACAAGGTGCTATACAGCCGTTAAACACCCCCTCCCTGCAAC TGTTTAAAATTAGAATAGATTTTTGCATCAACCACTGCTAGAAGCTTTCCCCACCTAGGTGGGCTGCAAGGGCCTGCATTCCCAACATCC CATTACATGTTTCCCACTCCAGAAAGTCTCTGGGTTTATTCCAGCTTTTTATCTTGACGTGTCCCATTCACCCCCATGGTTTGGTTTGGT TTGGTTTTGTTTTTTAAATCAAGAAAGTTTCAGGGAATCAAAAGAGGTCGGACATTTTTTAACCTAGCAGAAGTACAGAGTCATATATTT TGCTACGAATATTGTTGTAGTACAGAAAACCCACTTTGCCCGTTAGTGTGTGGATAGTATGTGTGTGTCCGCACTCATGATAACTTGAAT GTTGAACCAGACATAGGGTTCATTTTTGAAAGGTTAAACCACACTGTTTCAGGAACTTGCTCCAAATACTACTTGGTTATCCCTTCCTTT ACCAGTTAGAACTAAAGAGTGTGATGTATGAACACACTGGGTTGGGATTTTCTGTTGAGGATATGCAGGGCATTTTGGCATGAGGCAAAT ACAGAAGCAAGATTTCATTCTACTTGGTGATTTGAATCATGACAGTCCTCATTCCAATCTCTCTTTAATTCTCTCTGGCCCTGCCCACAC TCTGTATTTGAAAATCTTGTTTTTGCTCTTTCCGGAGCTTCACCCCTCTACTTACATATTGTAAAGTTGTATAAATCTATCATTGAAAGG TCCTCTCTGCCAGCAGTGGTGCCACCCTTTGGTTTGCTGTGGTACTTTGCTGTGTACTCCGTGGCATCATGTTACTGTGTAAATAAATTC >In-frame_NTRK3_ENST00000558676_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_7583nt CTCTTTTTTAGAAGCAGCGATCGGAGATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCT GGCTGGACTATGTGGGCTCCGTGCTGGCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGA ACCTCTTCCCCCTCCTGGAAGGGCAGGATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTT CCATACACATAGAGAACTGGCGCAGTCTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGA ACTCAGGACTTCGGAGCATTCAGCCCAGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCA GCAGTATTATCACAGCTTGGCTGTCCGGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCC TAACCGTCTGCTTCCCTGGGAGGATCCAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAAC GGATGGGAAAAACCCAAAGCCCTGTTCTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGT TGTGGTCATCACCAGGGAGGTTCCATGTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTA TGAGAGGCAGGTGTGTCTGCTGCTCTTACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCT AGAGAACCTGCTACTTGTCCACTACCAGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCAC TAGGCTTATAGTGAGCAACTTCTCTCAGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCC AGAGATCATAACAGCTACCCAGTATAAAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTT TGATGAGAACCCAGAGCTGAAGGAGAGGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCA GCAGCTGGCCAGCTGCCTCCTGAATCCCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGG CCCCCGCGAAGATCTCTTCCAGACTTTCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCG AACACTGCTCATGATCAAGTTTGCTGAGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGC TTTTGCCACTACAGACTCCCTCAGTTGTATTGTGAAAATTCTGCAGCACCGTTAATGTGTACCTGGATGATGCTTTTACTACATCTTCAC CTTCTTCATGTCACCCATGCACTTCCCCTCCCTAGTGCTCACTCCAAATTCAAGGAAAGAAGAAAGGCAAACCTCTATCCCTGTCCGTGA ACAAGTGGGTCTATTCAGAAAGGTTATCCACTGCCCCAGATTGAATGAGAAGCTGAGTCTGTCTTAACTTTACAGAAATTCAGCTGCACA AACTTGCAGTTGCCTTCCCTTGAAACACCTTCTATCCTAATAGTCCCATAAATGCAGGTAAAAATGAAAATCCATATTCTTGAAGGGACA GCTTCTTTGGTATGAACTCAGCCAGTGAGCTGTGTCCATTTCCTCCATAATTCTGGATATCACCTATCTTTTTAGCACCAAGTATTTATT CTCACTAGCAGTAGACAGACTTAACCAGTCTCTACCACGACCCAGTAGACTCTGACAACAGACTCTTCCTTTAAGGTGTCAACAACTGAC TTACTAGGCAGGACTGCCATCCTTAGCATCAGCCCAGTTTTGGTTACCAGGGACTATATCTTTTGTTCCAGGAGAGAGTAGAAAGAAAAG GAGAGATCCCATCCTTGGGTCATAGACCCATTTTCATTGCCATTATCTGTAAGTATGTGCACTGCATGGAGGACAGCCCTAATAGTCTCC CCTCTGCTGCCACTGCCTGATTCTCCACTCTGTCCCCACTTGCCAGTGAAGTTTGGATTTATCAGCCACTTGTGGCCCATTACAGAGCTG ACCCAAGGTGGTGTCACCAATGCCTCAGCAGGGTGGAGTGCAGTTCAGAGCTTATAAATAGCTGGCAGGGCATGAGGAGATGATTTTCTT GCATGTGCAATTCTCTAGGGGCCATCAGGAAACAGAGTTTAAAGTACCCTTTGATTACTGTCAGAACTGTCAGCATTTGCAGTTTTCCCC GAGCAGTAATTGGCCAGCTCCCTTCTATCAGTAGCCAGTGTTAACTAGTTTACCAAATGCTGTAAACAATTGCCCTGAATGAAATAGCTG TCAGTGGAGCTCTAAGATCTCCTTTAGAGGGCACAGTGAGGTGGGCTGTTGGGATGGCCGTAGGCAGGGGAGAGGAAGAAGGCCACTGAT GAGACTGCTGACCTCCTCAGAAGGTTGACCTCTTCTAGAGAGACTGCCTCCCAGTGTTTAAGTGGCTCATTGCTCCTTCTGACTCTGTAA AATGGCTCTGGAGGACAGCTCACAGGAATTCTGATTGCTGAGGTGGGTGATTGAGAGCTGTTCACCATGTGTGCAGCCTGTGCTCCCCTT CTATGGATATGTGTGCAATTTTTGTATGTATTTTTTTAGCTGTATATTACAGTGTTTATGTTGCAACTTCACCTGAAGCGAGTCTACAGA AACCCTCCCCCTTCTTCCCTTGGCACATATTTGCGCTAAGAGATGAGCGTTCCTTCCACTGGGGTTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTATGTATACACATGTTCACCTGTGCTTGTTTTATTCAAAACTGTGAGTATGTGTTTACTTTGACCTTGAAA TCCCAAGAGTCACTCGAACAATGTGTGTGTACACTTGTGTGCCCATGTGTGCGTGCACACGCATGCTGGAAGTAGAGGCCAGGCCTCTAG AAAAGCAACCTGTGGCAGGGTTGACAGACATGTTCTCTGTGCCTAGTGAGTGAGTGAGCCCTGAGGCCCCTCATCTACCAGTGCAGAGTT TCCTTAAAGCCAAGACTGACTGTGCAGTATTACTTACATAGCACATTAGTGGCCTTGGAAATTTCTAAACTTTTAACATTTTTAACAGCT TTTCATGTGATTCATGTATAACAAAGAGGATCAGGAAAGGAAAATAATGTATTTTATTGTGCTCTTATTACTTTTTTAAGTGATTGTAAT ATGTGAGGCTCTATTTGGAGAATGTCCCTTATCCCCTGGCCAGCAATATAGGACTCACAGGAAAGAAGGCTGGTTAGCCCACAAAGAGTC TTGCCTCCTCTAGCCAGAGTGCAGGGCTCTGCTCCTAGGAATGGCCATGGAGTGGGCATGCTGCTGCAGGCCAGCAGTCTGCTCTTGGTG TCCTGTGGCATGGCCGCGCCTTGCCTTGAAGGTTGGTGTTTGGTTCATCTTAGCATAGAACATGTGCACATAACTCCTTGCCTGATTATG CACTGAAGGGCAGCACACAGACCACTGACCATGTCAGCCAGCACATTCCCTTAACCTCCCCCACCTCCCATCTTGCAATGTCTTGCATAT TGAGATATACCTTCTCAATGTCATGTTCGTGGTGCCTTGCCCATGTAAATTTCAATGTTGACTATTTAATGAGGTTACATATTTAATGCT GAATGTTTCCTGGTCCCTCTATTTGTTATGTCTCTACTTATCTTTTTTTTTCTTTCTCTTTTTCTGTTATGATTTGGATCCAGTCTTCAC TTTAACTCTATGGTATAATAAGCATGGACACCTCCACTACCATTATCTTACAGCACTGGTAAACCAAGCACCTCTTCATATCAGATGTTT TTAGTACTGTTTTTATATTCAGATTTGTTAAGGGCAAAAGATGAATGCAAACTAGCCAGAGAAAAGCCTCAGGCTTCCCAGAGACAGGTG GCTAGATTAATTTTTCTCTGGGTGATGGCCAAAGAATGTGAGATAGAGAGGGAAGGGGGTGTTACAGGTTAGAGCAGAATAGAGAAAGAA ACTATATTTCTAGGCAAAAAGTACTACATGAGTTGGTCTTCAGAATATTTTTCCAAAAAAATGAAATTCAGTCAGTTTAACATTATCACA AATATTTTTCATTTTAATTGTGGTAGGACCTTTGAATTTGTTCATCAACTGGAAAGAAATCCTACCCTCTGTAGACACATACACACACAT TTATATATCTATGTGTTTGAATTGTGACTAGTATAGCACTTTACATTTTCTCAAGTAACAGGAAGTTATTGCCTTCAATATTGATTGGAA ATTGTTTTCTATTGAAGTCTATACTGTAGAGTTTTCCATTTATATTGAGAGTTTGAACAATTAAGCTCCTATTGGAACTTTTCCTTAAGC CACATGAGCATGAACAATCTCTGTGACACTTGGGTGCTAGAGAAACACAACAGTGGCTAAAGTAGCCAAGAGCAAGACTGAATGTATAGC AGAGTGCCTTGTTAGAGTGGTAACCTAGTCTTGGAAGCAATTCAGTGGATGTTTCATAAAGAGGACTAGAACTTCAAGAAGCCTCCTGTG CTGGCTGAGGTGAGCCCTTTTGGTATATGTACACTACTGGGTTGCCTAGAAGCCAATTCATGAAGAATAACAGCAGGATGAGAAAAAGAG TCACTGTAACCTGTGGAACAACAACGTAAGAATCACCAACCCCTAGGCTGAGCTAGAACTGGAAGCCAGGAATATGGCAATGAGTTTCAA GATTTGCCCTCAGAAGATGAACTGGGTGAGGTATGGGTTGAGGTGAGGGCACAAGCACTCATCCTACCTACCCTGCTGCTGTTGAGGAGC TAGAAGTAAAACATATTGGTTAGGATTTTAACAGTTGGAGTAGCCTCCCATTATCAGATTAAGTGGGGGTCACTTTTGCTTCCAAACTCA GAATAAGTTTGTAAACATGGGAAAGTCTAAGCCAAGAGATCTAAAGCTCTAGAAATATTAATGACATTTCTGGGAGTAAAACTACTAAAA ATTATATCTTAAAAGTTTCTAGTAGTATGAAGTTCCCAGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGGCGAGG TGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCATCTCTACTAAAAATACAAAAATTAGCCGGG CATGATGGCAGGCACCTGTAATCTAAGCTACTCGGGAGGCTGAGGCAAGAGAATCTCTTGAACCCAGGAGGCAAAGGTTGCAGTGAGCCA AGATCACGCCATCGCACTCCAGCCTGGGAGATTGAGCAACTTCGTCTCAAAAAAAAGTTTCCAGGAAAGATCTTTGGGTCCTACTAAGCG TCTCAATTTTGAGTTATGAATACTTTGGTTCAGGGAAGTAACCTGACATTTGGTTTTGCTGGAATTAGGGTTTTCGCTAGATTTGACTGC AATTAGGATTTCTTCTAGATTTTACCAGCAGTGATCTGAAAAAGTACAGGCTAGTCACAGAAATAGAGATGGATTTAGGATACTACACTA TATTTCAAATGATTCTAGATGTGTAAATATAGTATGAACATTCTTGGAGAGGGGTGAGACAAACTGGACTTGCTGGGCCAACCCTGGCAT GTTTTTCATTCTCCTCACTAGTTGACAAGGATTGAAAATTCCGCTCCAGCCTAATGAGTGAACAGGATGGCTGCCCACAAAACCAAGTTA TTAGCTTTATGTCATCGAAGCTCATATTCTCAAAGGCCCAAAGTGCTGTGCCGAGACAAATCCAAGTGCTGCTCTTGCTGAAGTGCGCAC TGAAGTCCAGCTGTCCGTGCTTACAGCAGTGCCAAAAGTGGGGATTCCATGGACCAAAAACGGTGCCATAAGGGAAGCCAGAAGAGTTGC AGTGCAAGATCCTGGGAGAGATTATACCAAAGAAATCAAGCCTTTTTATCCTGATGCTTCTAAGATGATGAGGGTGAGCTGTGACAGATG CTGTGGGAGGGGAGTTCACATACATTCCATGTCAAGGCATTTAGCTGATAAATCCATCCTCAGAAAAGCACCTTTTTAAAAAGAAGTCCA TTTTGTATATTAGAAGATGATGATGATGATGAAGATGAAGAAAGCCCTGGCAGATACAAAGTTCCTCAGTATTTAAGGAGAAGGATCTCT TCCATGTCCCCTTGACATGACTGTGGCTATTGCCCAAACCTCAGCTTGAGAACATCATATAATACTGAGAGCGGAAGATTTTTTTAAAGA GATATGGTAGTTTAAATAGGTTTGTTTAAAGAACTCTTGGGAAATTTCTTAACAAATTGTAATTGTTTTTATAAACCTTCCTACAGAGTT GTGTACCATTCATCATCACCATCATTTAATATCTGTAAGTGCCCAGAAGGTACAAGGTGCTATACAGCCGTTAAACACCCCCTCCCTGCA ACTGTTTAAAATTAGAATAGATTTTTGCATCAACCACTGCTAGAAGCTTTCCCCACCTAGGTGGGCTGCAAGGGCCTGCATTCCCAACAT CCCATTACATGTTTCCCACTCCAGAAAGTCTCTGGGTTTATTCCAGCTTTTTATCTTGACGTGTCCCATTCACCCCCATGGTTTGGTTTG GTTTGGTTTTGTTTTTTAAATCAAGAAAGTTTCAGGGAATCAAAAGAGGTCGGACATTTTTTAACCTAGCAGAAGTACAGAGTCATATAT TTTGCTACGAATATTGTTGTAGTACAGAAAACCCACTTTGCCCGTTAGTGTGTGGATAGTATGTGTGTGTCCGCACTCATGATAACTTGA ATGTTGAACCAGACATAGGGTTCATTTTTGAAAGGTTAAACCACACTGTTTCAGGAACTTGCTCCAAATACTACTTGGTTATCCCTTCCT TTACCAGTTAGAACTAAAGAGTGTGATGTATGAACACACTGGGTTGGGATTTTCTGTTGAGGATATGCAGGGCATTTTGGCATGAGGCAA ATACAGAAGCAAGATTTCATTCTACTTGGTGATTTGAATCATGACAGTCCTCATTCCAATCTCTCTTTAATTCTCTCTGGCCCTGCCCAC ACTCTGTATTTGAAAATCTTGTTTTTGCTCTTTCCGGAGCTTCACCCCTCTACTTACATATTGTAAAGTTGTATAAATCTATCATTGAAA GGTCCTCTCTGCCAGCAGTGGTGCCACCCTTTGGTTTGCTGTGGTACTTTGCTGTGTACTCCGTGGCATCATGTTACTGTGTAAATAAAT >In-frame_NTRK3_ENST00000540489_chr15_88726649_-_PEAK1_ENST00000560626_chr15_77407661_-_7563nt TCGGAGATGGATGTCTCTCTTTGCCCAGCCAAGTGTAGTTTCTGGCGGATTTTCTTGCTGGGAAGCGTCTGGCTGGACTATGTGGGCTCC GTGCTGGCTTGCCCTGCAAATTGTGTCTGCAGCAAGACTGAGATCAATTGCCGGCGGCCGGACGATGGGAACCTCTTCCCCCTCCTGGAA GGGCAGGATTCAGGGAACAGCAATGGGAACGCCAGTATCAACATCACGGACATCTCAAGGAATATCACTTCCATACACATAGAGAACTGG CGCAGTCTTCACACGCTCAACGCCGTGGACATGGAGCTCTACACCGGACTTCAAAAGCTGACCATCAAGAACTCAGGACTTCGGAGCATT CAGCCCAGAGCCTTTGCCAAGAACCCCCATTTGCGTTATATATCTGTAAGAGCAAAGCTAAAGAATCTCAGCAGTATTATCACAGCTTGG CTGTCCGGCAGAGTCTGGCTGTCCATTTTAACATTCAGCAGGACTGTGGTCATTTCCTTGCTGAAGTCCCTAACCGTCTGCTTCCCTGGG AGGATCCAGATGACCCTGAAAAGGATGAGGATGACATGGAAGAGACTGAAGAAGACGCCAAAGGAGAAACGGATGGGAAAAACCCAAAGC CCTGTTCTGAAGCAGCATCATCCCAGAAAGAGAATCAGGGAGTCATGAGCAAGAAGCAGAGGAGCCACGTTGTGGTCATCACCAGGGAGG TTCCATGTCTTACTGTGGCTGATTTTGTGCGAGACTCTCTGGCCCAGCATGGGAAAAGCCCTGATTTGTATGAGAGGCAGGTGTGTCTGC TGCTCTTACAGCTATGCTCTGGTCTTGAGCACCTCAAACCCTACCATGTCACTCACTGCGATCTACGCCTAGAGAACCTGCTACTTGTCC ACTACCAGCCTGGGGGGACTGCCCAAGGCTTTGGGCCTGCAGAGCCCAGCCCCACCTCATCTTATCCCACTAGGCTTATAGTGAGCAACT TCTCTCAGGCCAAGCAGAAGAGCCATCTGGTGGACCCCGAGATCCTCCGGGACCAGTCTCGCCTTGCCCCAGAGATCATAACAGCTACCC AGTATAAAAAGTGTGATGAGTTCCAGACAGGCATCCTCATCTATGAGATGCTGCACCTACCCAACCCCTTTGATGAGAACCCAGAGCTGA AGGAGAGGGAATACACACGAGCAGACCTGCCTCGCATCCCATTCCGCTCCCCCTACTCCCGGGGTCTGCAGCAGCTGGCCAGCTGCCTCC TGAATCCCAACCCTTCTGAGCGGATCCTCATTTCAGACGCCAAAGGCATCCTCCAGTGTCTGCTCTGGGGCCCCCGCGAAGATCTCTTCC AGACTTTCACCGCCTGCCCTAGCCTAGTACAGAGGAACACCCTGCTCCAAAACTGGCTAGACATCAAGCGAACACTGCTCATGATCAAGT TTGCTGAGAAGTCCCTGGACAGGGAAGGTGGAATCAGCCTTGAGGACTGGCTTTGTGCTCAGTATTTGGCTTTTGCCACTACAGACTCCC TCAGTTGTATTGTGAAAATTCTGCAGCACCGTTAATGTGTACCTGGATGATGCTTTTACTACATCTTCACCTTCTTCATGTCACCCATGC ACTTCCCCTCCCTAGTGCTCACTCCAAATTCAAGGAAAGAAGAAAGGCAAACCTCTATCCCTGTCCGTGAACAAGTGGGTCTATTCAGAA AGGTTATCCACTGCCCCAGATTGAATGAGAAGCTGAGTCTGTCTTAACTTTACAGAAATTCAGCTGCACAAACTTGCAGTTGCCTTCCCT TGAAACACCTTCTATCCTAATAGTCCCATAAATGCAGGTAAAAATGAAAATCCATATTCTTGAAGGGACAGCTTCTTTGGTATGAACTCA GCCAGTGAGCTGTGTCCATTTCCTCCATAATTCTGGATATCACCTATCTTTTTAGCACCAAGTATTTATTCTCACTAGCAGTAGACAGAC TTAACCAGTCTCTACCACGACCCAGTAGACTCTGACAACAGACTCTTCCTTTAAGGTGTCAACAACTGACTTACTAGGCAGGACTGCCAT CCTTAGCATCAGCCCAGTTTTGGTTACCAGGGACTATATCTTTTGTTCCAGGAGAGAGTAGAAAGAAAAGGAGAGATCCCATCCTTGGGT CATAGACCCATTTTCATTGCCATTATCTGTAAGTATGTGCACTGCATGGAGGACAGCCCTAATAGTCTCCCCTCTGCTGCCACTGCCTGA TTCTCCACTCTGTCCCCACTTGCCAGTGAAGTTTGGATTTATCAGCCACTTGTGGCCCATTACAGAGCTGACCCAAGGTGGTGTCACCAA TGCCTCAGCAGGGTGGAGTGCAGTTCAGAGCTTATAAATAGCTGGCAGGGCATGAGGAGATGATTTTCTTGCATGTGCAATTCTCTAGGG GCCATCAGGAAACAGAGTTTAAAGTACCCTTTGATTACTGTCAGAACTGTCAGCATTTGCAGTTTTCCCCGAGCAGTAATTGGCCAGCTC CCTTCTATCAGTAGCCAGTGTTAACTAGTTTACCAAATGCTGTAAACAATTGCCCTGAATGAAATAGCTGTCAGTGGAGCTCTAAGATCT CCTTTAGAGGGCACAGTGAGGTGGGCTGTTGGGATGGCCGTAGGCAGGGGAGAGGAAGAAGGCCACTGATGAGACTGCTGACCTCCTCAG AAGGTTGACCTCTTCTAGAGAGACTGCCTCCCAGTGTTTAAGTGGCTCATTGCTCCTTCTGACTCTGTAAAATGGCTCTGGAGGACAGCT CACAGGAATTCTGATTGCTGAGGTGGGTGATTGAGAGCTGTTCACCATGTGTGCAGCCTGTGCTCCCCTTCTATGGATATGTGTGCAATT TTTGTATGTATTTTTTTAGCTGTATATTACAGTGTTTATGTTGCAACTTCACCTGAAGCGAGTCTACAGAAACCCTCCCCCTTCTTCCCT TGGCACATATTTGCGCTAAGAGATGAGCGTTCCTTCCACTGGGGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT ATGTATACACATGTTCACCTGTGCTTGTTTTATTCAAAACTGTGAGTATGTGTTTACTTTGACCTTGAAATCCCAAGAGTCACTCGAACA ATGTGTGTGTACACTTGTGTGCCCATGTGTGCGTGCACACGCATGCTGGAAGTAGAGGCCAGGCCTCTAGAAAAGCAACCTGTGGCAGGG TTGACAGACATGTTCTCTGTGCCTAGTGAGTGAGTGAGCCCTGAGGCCCCTCATCTACCAGTGCAGAGTTTCCTTAAAGCCAAGACTGAC TGTGCAGTATTACTTACATAGCACATTAGTGGCCTTGGAAATTTCTAAACTTTTAACATTTTTAACAGCTTTTCATGTGATTCATGTATA ACAAAGAGGATCAGGAAAGGAAAATAATGTATTTTATTGTGCTCTTATTACTTTTTTAAGTGATTGTAATATGTGAGGCTCTATTTGGAG AATGTCCCTTATCCCCTGGCCAGCAATATAGGACTCACAGGAAAGAAGGCTGGTTAGCCCACAAAGAGTCTTGCCTCCTCTAGCCAGAGT GCAGGGCTCTGCTCCTAGGAATGGCCATGGAGTGGGCATGCTGCTGCAGGCCAGCAGTCTGCTCTTGGTGTCCTGTGGCATGGCCGCGCC TTGCCTTGAAGGTTGGTGTTTGGTTCATCTTAGCATAGAACATGTGCACATAACTCCTTGCCTGATTATGCACTGAAGGGCAGCACACAG ACCACTGACCATGTCAGCCAGCACATTCCCTTAACCTCCCCCACCTCCCATCTTGCAATGTCTTGCATATTGAGATATACCTTCTCAATG TCATGTTCGTGGTGCCTTGCCCATGTAAATTTCAATGTTGACTATTTAATGAGGTTACATATTTAATGCTGAATGTTTCCTGGTCCCTCT ATTTGTTATGTCTCTACTTATCTTTTTTTTTCTTTCTCTTTTTCTGTTATGATTTGGATCCAGTCTTCACTTTAACTCTATGGTATAATA AGCATGGACACCTCCACTACCATTATCTTACAGCACTGGTAAACCAAGCACCTCTTCATATCAGATGTTTTTAGTACTGTTTTTATATTC AGATTTGTTAAGGGCAAAAGATGAATGCAAACTAGCCAGAGAAAAGCCTCAGGCTTCCCAGAGACAGGTGGCTAGATTAATTTTTCTCTG GGTGATGGCCAAAGAATGTGAGATAGAGAGGGAAGGGGGTGTTACAGGTTAGAGCAGAATAGAGAAAGAAACTATATTTCTAGGCAAAAA GTACTACATGAGTTGGTCTTCAGAATATTTTTCCAAAAAAATGAAATTCAGTCAGTTTAACATTATCACAAATATTTTTCATTTTAATTG TGGTAGGACCTTTGAATTTGTTCATCAACTGGAAAGAAATCCTACCCTCTGTAGACACATACACACACATTTATATATCTATGTGTTTGA ATTGTGACTAGTATAGCACTTTACATTTTCTCAAGTAACAGGAAGTTATTGCCTTCAATATTGATTGGAAATTGTTTTCTATTGAAGTCT ATACTGTAGAGTTTTCCATTTATATTGAGAGTTTGAACAATTAAGCTCCTATTGGAACTTTTCCTTAAGCCACATGAGCATGAACAATCT CTGTGACACTTGGGTGCTAGAGAAACACAACAGTGGCTAAAGTAGCCAAGAGCAAGACTGAATGTATAGCAGAGTGCCTTGTTAGAGTGG TAACCTAGTCTTGGAAGCAATTCAGTGGATGTTTCATAAAGAGGACTAGAACTTCAAGAAGCCTCCTGTGCTGGCTGAGGTGAGCCCTTT TGGTATATGTACACTACTGGGTTGCCTAGAAGCCAATTCATGAAGAATAACAGCAGGATGAGAAAAAGAGTCACTGTAACCTGTGGAACA ACAACGTAAGAATCACCAACCCCTAGGCTGAGCTAGAACTGGAAGCCAGGAATATGGCAATGAGTTTCAAGATTTGCCCTCAGAAGATGA ACTGGGTGAGGTATGGGTTGAGGTGAGGGCACAAGCACTCATCCTACCTACCCTGCTGCTGTTGAGGAGCTAGAAGTAAAACATATTGGT TAGGATTTTAACAGTTGGAGTAGCCTCCCATTATCAGATTAAGTGGGGGTCACTTTTGCTTCCAAACTCAGAATAAGTTTGTAAACATGG GAAAGTCTAAGCCAAGAGATCTAAAGCTCTAGAAATATTAATGACATTTCTGGGAGTAAAACTACTAAAAATTATATCTTAAAAGTTTCT AGTAGTATGAAGTTCCCAGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGGCGAGGTGGGCAGATCACCTGAGGTC AGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCATCTCTACTAAAAATACAAAAATTAGCCGGGCATGATGGCAGGCACCTGTA ATCTAAGCTACTCGGGAGGCTGAGGCAAGAGAATCTCTTGAACCCAGGAGGCAAAGGTTGCAGTGAGCCAAGATCACGCCATCGCACTCC AGCCTGGGAGATTGAGCAACTTCGTCTCAAAAAAAAGTTTCCAGGAAAGATCTTTGGGTCCTACTAAGCGTCTCAATTTTGAGTTATGAA TACTTTGGTTCAGGGAAGTAACCTGACATTTGGTTTTGCTGGAATTAGGGTTTTCGCTAGATTTGACTGCAATTAGGATTTCTTCTAGAT TTTACCAGCAGTGATCTGAAAAAGTACAGGCTAGTCACAGAAATAGAGATGGATTTAGGATACTACACTATATTTCAAATGATTCTAGAT GTGTAAATATAGTATGAACATTCTTGGAGAGGGGTGAGACAAACTGGACTTGCTGGGCCAACCCTGGCATGTTTTTCATTCTCCTCACTA GTTGACAAGGATTGAAAATTCCGCTCCAGCCTAATGAGTGAACAGGATGGCTGCCCACAAAACCAAGTTATTAGCTTTATGTCATCGAAG CTCATATTCTCAAAGGCCCAAAGTGCTGTGCCGAGACAAATCCAAGTGCTGCTCTTGCTGAAGTGCGCACTGAAGTCCAGCTGTCCGTGC TTACAGCAGTGCCAAAAGTGGGGATTCCATGGACCAAAAACGGTGCCATAAGGGAAGCCAGAAGAGTTGCAGTGCAAGATCCTGGGAGAG ATTATACCAAAGAAATCAAGCCTTTTTATCCTGATGCTTCTAAGATGATGAGGGTGAGCTGTGACAGATGCTGTGGGAGGGGAGTTCACA TACATTCCATGTCAAGGCATTTAGCTGATAAATCCATCCTCAGAAAAGCACCTTTTTAAAAAGAAGTCCATTTTGTATATTAGAAGATGA TGATGATGATGAAGATGAAGAAAGCCCTGGCAGATACAAAGTTCCTCAGTATTTAAGGAGAAGGATCTCTTCCATGTCCCCTTGACATGA CTGTGGCTATTGCCCAAACCTCAGCTTGAGAACATCATATAATACTGAGAGCGGAAGATTTTTTTAAAGAGATATGGTAGTTTAAATAGG TTTGTTTAAAGAACTCTTGGGAAATTTCTTAACAAATTGTAATTGTTTTTATAAACCTTCCTACAGAGTTGTGTACCATTCATCATCACC ATCATTTAATATCTGTAAGTGCCCAGAAGGTACAAGGTGCTATACAGCCGTTAAACACCCCCTCCCTGCAACTGTTTAAAATTAGAATAG ATTTTTGCATCAACCACTGCTAGAAGCTTTCCCCACCTAGGTGGGCTGCAAGGGCCTGCATTCCCAACATCCCATTACATGTTTCCCACT CCAGAAAGTCTCTGGGTTTATTCCAGCTTTTTATCTTGACGTGTCCCATTCACCCCCATGGTTTGGTTTGGTTTGGTTTTGTTTTTTAAA TCAAGAAAGTTTCAGGGAATCAAAAGAGGTCGGACATTTTTTAACCTAGCAGAAGTACAGAGTCATATATTTTGCTACGAATATTGTTGT AGTACAGAAAACCCACTTTGCCCGTTAGTGTGTGGATAGTATGTGTGTGTCCGCACTCATGATAACTTGAATGTTGAACCAGACATAGGG TTCATTTTTGAAAGGTTAAACCACACTGTTTCAGGAACTTGCTCCAAATACTACTTGGTTATCCCTTCCTTTACCAGTTAGAACTAAAGA GTGTGATGTATGAACACACTGGGTTGGGATTTTCTGTTGAGGATATGCAGGGCATTTTGGCATGAGGCAAATACAGAAGCAAGATTTCAT TCTACTTGGTGATTTGAATCATGACAGTCCTCATTCCAATCTCTCTTTAATTCTCTCTGGCCCTGCCCACACTCTGTATTTGAAAATCTT GTTTTTGCTCTTTCCGGAGCTTCACCCCTCTACTTACATATTGTAAAGTTGTATAAATCTATCATTGAAAGGTCCTCTCTGCCAGCAGTG GTGCCACCCTTTGGTTTGCTGTGGTACTTTGCTGTGTACTCCGTGGCATCATGTTACTGTGTAAATAAATTCATTTTAATACACACTAAA |
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FusionGenePPI for NTRK3_PEAK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NTRK3 | NTF3, FRS2, SHC1, PLCG1, SQSTM1, PTPN1, APP, HSP90AA1, IRAK3, TNK2, NTRK1, SH3BP4, PTPRS, MYADM, C1GALT1, GNB2, C6orf120, MTOR, LGALS1, PTCD2, TMEM11, PAG1, EFR3A, TBC1D24, GNB4, TMEM192, INTS7, DENND4A, FAM171A2, KIAA0391, EPHA2, ATP7B, CXCR4, ACAD10, HRAS, EHD4, RPTOR, HEATR6, SLC39A11 | PEAK1 | CRK, GRB2, PPP1CC, PPP1CA, NCK2, CARD8, SH2D2A, AURKA, PPP1R3A, CRKL, SORT1, XRCC5, TOR1AIP1, CDH1, PTPRK, SHC1, VWA5A, BBS7, DQX1, PCDHB11, AARSD1, MTNR1B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NTRK3_PEAK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NTRK3_PEAK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NTRK3 | C0036341 | Schizophrenia | 3 | PSYGENET |
| Hgene | NTRK3 | C0041696 | Unipolar Depression | 2 | PSYGENET |
| Hgene | NTRK3 | C1269683 | Major Depressive Disorder | 2 | PSYGENET |
| Hgene | NTRK3 | C0014175 | Endometriosis | 1 | CTD_human |
| Hgene | NTRK3 | C0017638 | Glioma | 1 | CTD_human |
| Hgene | NTRK3 | C0038220 | Status Epilepticus | 1 | CTD_human |
| Hgene | NTRK3 | C0525045 | Mood Disorders | 1 | PSYGENET |
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