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Fusion gene ID: 24955 |
FusionGeneSummary for NSRP1_ANKRD13B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NSRP1_ANKRD13B | Fusion gene ID: 24955 | Hgene | Tgene | Gene symbol | NSRP1 | ANKRD13B | Gene ID | 84081 | 124930 |
| Gene name | nuclear speckle splicing regulatory protein 1 | ankyrin repeat domain 13B | |
| Synonyms | CCDC55|HSPC095|NSrp70 | - | |
| Cytomap | 17q11.2 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nuclear speckle splicing regulatory protein 1coiled-coil domain containing 55coiled-coil domain-containing protein 55nuclear speckle-related protein 70 | ankyrin repeat domain-containing protein 13B | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9H0G5 | Q86YJ7 | |
| Ensembl transtripts involved in fusion gene | ENST00000540900, ENST00000584423, ENST00000247026, ENST00000479218, | ENST00000394859, | |
| Fusion gene scores | * DoF score | 7 X 5 X 4=140 | 3 X 1 X 3=9 |
| # samples | 8 | 4 | |
| ** MAII score | log2(8/140*10)=-0.807354922057604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/9*10)=2.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NSRP1 [Title/Abstract] AND ANKRD13B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NSRP1 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome | 21296756 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A2-A25B-01A | NSRP1 | chr17 | 28445191 | + | ANKRD13B | chr17 | 27934760 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000540900 | ENST00000394859 | NSRP1 | chr17 | 28445191 | + | ANKRD13B | chr17 | 27934760 | + |
| In-frame | ENST00000584423 | ENST00000394859 | NSRP1 | chr17 | 28445191 | + | ANKRD13B | chr17 | 27934760 | + |
| In-frame | ENST00000247026 | ENST00000394859 | NSRP1 | chr17 | 28445191 | + | ANKRD13B | chr17 | 27934760 | + |
| 3UTR-3CDS | ENST00000479218 | ENST00000394859 | NSRP1 | chr17 | 28445191 | + | ANKRD13B | chr17 | 27934760 | + |
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FusionProtFeatures for NSRP1_ANKRD13B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NSRP1 | ANKRD13B |
| RNA-binding protein that mediates pre-mRNA alternativesplicing regulation. {ECO:0000269|PubMed:21296756}. | Ubiquitin-binding protein that specifically recognizesand binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linkedubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFRat the cell membrane. {ECO:0000269|PubMed:22298428}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NSRP1_ANKRD13B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NSRP1_ENST00000584423_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_627aa MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDEVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVS TRDLELVQLVLRYRDYQRVVKRLAGIPVLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGN RSFVFRGQDTSAVVMEIDHDRRVVYTETLALAGQDRELLLAAAQPTEEQVLSRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNG YEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPME LTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSP SSETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSMMGGQREAATRDDDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTH >In-frame_NSRP1_ENST00000247026_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_627aa MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDEVDIEQLDPRGRTPLHLATTLGHLECARVLLAHGADVGRENRSGWTVLQEAVS TRDLELVQLVLRYRDYQRVVKRLAGIPVLLEKLRKAQDFYVEMKWEFTSWVPLVSKICPSDTYKVWKSGQNLRVDTTLLGFDHMTWQRGN RSFVFRGQDTSAVVMEIDHDRRVVYTETLALAGQDRELLLAAAQPTEEQVLSRLTAPVVTTQLDTKNISFERNKTGILGWRSEKTEMVNG YEAKVYGASNVELITRTRTEHLSEQHKGKVKGCKTPLQSFLGIAEQHGGPQNGTLITQTLSQANPTAITAEEYFNPNFELGNRDMGRPME LTTKTQKFKAKLWLCEEHPLSLCEQVAPIIDLMAVSNALFAKLRDFITLRLPPGFPVKIEIPIFHILNARITFGNLNGCDEPVPSVRGSP SSETPSPGSDSSSVSSSSSTTSCRGCEISPALFEAPRGYSMMGGQREAATRDDDDDLLQFAIQQSLLEAGSEYDQVTIWEALTNSKPGTH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NSRP1_ENST00000584423_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_1881nt ATGGCGATTCCGGGCAGGCAGTATGGGCTTATTTTGCCAAAGAAAACACAGCAGTTGCACCCTGTTTTGCAAAAACCATCAGTGTTTGGG AATGATTCTGATGATGATGATGAGGTGGACATCGAGCAGCTGGATCCCCGCGGCCGGACTCCCCTGCACCTGGCCACCACGCTGGGGCAC CTTGAGTGTGCCCGTGTGCTCCTGGCGCACGGCGCAGACGTGGGCAGGGAGAATCGCAGCGGCTGGACAGTGCTCCAGGAGGCTGTGAGT ACCCGGGACCTGGAGCTGGTGCAGCTGGTGCTTCGGTACCGGGACTACCAGCGGGTGGTGAAGCGGCTGGCGGGCATCCCCGTGCTCCTG GAGAAGCTGCGCAAGGCCCAGGACTTCTACGTGGAGATGAAATGGGAGTTCACTAGCTGGGTGCCCCTGGTGTCCAAGATCTGCCCTAGT GACACCTACAAAGTGTGGAAGAGCGGCCAGAACCTGAGGGTAGACACCACACTCCTGGGCTTTGACCACATGACCTGGCAGCGAGGGAAC CGCAGCTTTGTCTTCAGGGGCCAAGACACAAGCGCCGTGGTCATGGAGATTGACCACGACCGCCGGGTGGTGTACACAGAGACTCTGGCA CTGGCTGGGCAGGACCGGGAGCTGCTGCTGGCTGCTGCTCAGCCCACTGAGGAACAGGTGCTGAGCCGGCTTACCGCGCCCGTCGTCACC ACTCAGCTTGACACCAAGAATATCTCCTTTGAGAGGAACAAGACTGGCATCCTGGGCTGGCGCAGTGAAAAGACGGAGATGGTGAATGGG TATGAAGCTAAGGTGTATGGGGCATCTAACGTGGAGCTCATCACCCGCACACGGACAGAACATCTTTCAGAACAGCACAAGGGCAAGGTC AAAGGCTGTAAGACACCTTTGCAGTCCTTCCTGGGAATCGCTGAGCAGCACGGGGGCCCCCAAAATGGGACCCTGATCACTCAGACTCTG AGCCAAGCCAACCCCACTGCCATCACTGCAGAAGAATACTTCAACCCCAACTTTGAGCTGGGCAACCGTGATATGGGCCGCCCCATGGAA CTGACCACCAAGACACAGAAGTTCAAGGCCAAGCTGTGGCTGTGTGAGGAGCATCCCCTGTCCCTGTGTGAGCAGGTGGCCCCCATCATT GACCTCATGGCCGTCAGCAATGCGCTTTTTGCCAAGCTCCGGGACTTCATCACCCTGCGTCTGCCTCCTGGCTTCCCAGTTAAGATTGAA ATCCCGATCTTCCACATCCTCAACGCCCGCATCACCTTCGGGAACCTCAACGGCTGCGACGAACCGGTGCCATCGGTGCGAGGCAGCCCC AGCAGCGAGACGCCTTCCCCAGGCAGCGACTCCTCCAGCGTCAGCAGCTCCAGCTCCACGACCTCCTGCCGCGGCTGCGAGATCTCCCCA GCGTTGTTCGAGGCCCCGCGCGGCTACAGCATGATGGGCGGCCAGCGGGAGGCGGCGACCCGGGACGACGACGACGACCTGCTGCAATTC GCCATCCAGCAGAGCCTGCTTGAGGCGGGCAGTGAGTATGACCAGGTCACCATCTGGGAGGCGCTAACCAACAGCAAGCCAGGCACCCAC CCCATGTCCTACGAGGGTCGCCGACAGGACAGGAGCGCCCCGCCCACGCCGCAGCGCCAGCCTGCGCCCCCGGCGTCAGTGCCCAGCCCT CGGCCCAGCTCAGGGCCAGGTTCCGGCGGCCACGTGTTCCGGAGCTACGACGAGCAGCTGCGGCTGGCGATGGAACTGTCGGCGCAGGAG >In-frame_NSRP1_ENST00000247026_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_1881nt ATGGCGATTCCGGGCAGGCAGTATGGGCTTATTTTGCCAAAGAAAACACAGCAGTTGCACCCTGTTTTGCAAAAACCATCAGTGTTTGGG AATGATTCTGATGATGATGATGAGGTGGACATCGAGCAGCTGGATCCCCGCGGCCGGACTCCCCTGCACCTGGCCACCACGCTGGGGCAC CTTGAGTGTGCCCGTGTGCTCCTGGCGCACGGCGCAGACGTGGGCAGGGAGAATCGCAGCGGCTGGACAGTGCTCCAGGAGGCTGTGAGT ACCCGGGACCTGGAGCTGGTGCAGCTGGTGCTTCGGTACCGGGACTACCAGCGGGTGGTGAAGCGGCTGGCGGGCATCCCCGTGCTCCTG GAGAAGCTGCGCAAGGCCCAGGACTTCTACGTGGAGATGAAATGGGAGTTCACTAGCTGGGTGCCCCTGGTGTCCAAGATCTGCCCTAGT GACACCTACAAAGTGTGGAAGAGCGGCCAGAACCTGAGGGTAGACACCACACTCCTGGGCTTTGACCACATGACCTGGCAGCGAGGGAAC CGCAGCTTTGTCTTCAGGGGCCAAGACACAAGCGCCGTGGTCATGGAGATTGACCACGACCGCCGGGTGGTGTACACAGAGACTCTGGCA CTGGCTGGGCAGGACCGGGAGCTGCTGCTGGCTGCTGCTCAGCCCACTGAGGAACAGGTGCTGAGCCGGCTTACCGCGCCCGTCGTCACC ACTCAGCTTGACACCAAGAATATCTCCTTTGAGAGGAACAAGACTGGCATCCTGGGCTGGCGCAGTGAAAAGACGGAGATGGTGAATGGG TATGAAGCTAAGGTGTATGGGGCATCTAACGTGGAGCTCATCACCCGCACACGGACAGAACATCTTTCAGAACAGCACAAGGGCAAGGTC AAAGGCTGTAAGACACCTTTGCAGTCCTTCCTGGGAATCGCTGAGCAGCACGGGGGCCCCCAAAATGGGACCCTGATCACTCAGACTCTG AGCCAAGCCAACCCCACTGCCATCACTGCAGAAGAATACTTCAACCCCAACTTTGAGCTGGGCAACCGTGATATGGGCCGCCCCATGGAA CTGACCACCAAGACACAGAAGTTCAAGGCCAAGCTGTGGCTGTGTGAGGAGCATCCCCTGTCCCTGTGTGAGCAGGTGGCCCCCATCATT GACCTCATGGCCGTCAGCAATGCGCTTTTTGCCAAGCTCCGGGACTTCATCACCCTGCGTCTGCCTCCTGGCTTCCCAGTTAAGATTGAA ATCCCGATCTTCCACATCCTCAACGCCCGCATCACCTTCGGGAACCTCAACGGCTGCGACGAACCGGTGCCATCGGTGCGAGGCAGCCCC AGCAGCGAGACGCCTTCCCCAGGCAGCGACTCCTCCAGCGTCAGCAGCTCCAGCTCCACGACCTCCTGCCGCGGCTGCGAGATCTCCCCA GCGTTGTTCGAGGCCCCGCGCGGCTACAGCATGATGGGCGGCCAGCGGGAGGCGGCGACCCGGGACGACGACGACGACCTGCTGCAATTC GCCATCCAGCAGAGCCTGCTTGAGGCGGGCAGTGAGTATGACCAGGTCACCATCTGGGAGGCGCTAACCAACAGCAAGCCAGGCACCCAC CCCATGTCCTACGAGGGTCGCCGACAGGACAGGAGCGCCCCGCCCACGCCGCAGCGCCAGCCTGCGCCCCCGGCGTCAGTGCCCAGCCCT CGGCCCAGCTCAGGGCCAGGTTCCGGCGGCCACGTGTTCCGGAGCTACGACGAGCAGCTGCGGCTGGCGATGGAACTGTCGGCGCAGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NSRP1_ENST00000584423_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_3123nt CGTGACGACATCGGCGTCAGCGTCACGGAGGCGTCGGCCACGTTCAGCGGACACGGGAGCAAGATGGCGATTCCGGGCAGGCAGTATGGG CTTATTTTGCCAAAGAAAACACAGCAGTTGCACCCTGTTTTGCAAAAACCATCAGTGTTTGGGAATGATTCTGATGATGATGATGAGGTG GACATCGAGCAGCTGGATCCCCGCGGCCGGACTCCCCTGCACCTGGCCACCACGCTGGGGCACCTTGAGTGTGCCCGTGTGCTCCTGGCG CACGGCGCAGACGTGGGCAGGGAGAATCGCAGCGGCTGGACAGTGCTCCAGGAGGCTGTGAGTACCCGGGACCTGGAGCTGGTGCAGCTG GTGCTTCGGTACCGGGACTACCAGCGGGTGGTGAAGCGGCTGGCGGGCATCCCCGTGCTCCTGGAGAAGCTGCGCAAGGCCCAGGACTTC TACGTGGAGATGAAATGGGAGTTCACTAGCTGGGTGCCCCTGGTGTCCAAGATCTGCCCTAGTGACACCTACAAAGTGTGGAAGAGCGGC CAGAACCTGAGGGTAGACACCACACTCCTGGGCTTTGACCACATGACCTGGCAGCGAGGGAACCGCAGCTTTGTCTTCAGGGGCCAAGAC ACAAGCGCCGTGGTCATGGAGATTGACCACGACCGCCGGGTGGTGTACACAGAGACTCTGGCACTGGCTGGGCAGGACCGGGAGCTGCTG CTGGCTGCTGCTCAGCCCACTGAGGAACAGGTGCTGAGCCGGCTTACCGCGCCCGTCGTCACCACTCAGCTTGACACCAAGAATATCTCC TTTGAGAGGAACAAGACTGGCATCCTGGGCTGGCGCAGTGAAAAGACGGAGATGGTGAATGGGTATGAAGCTAAGGTGTATGGGGCATCT AACGTGGAGCTCATCACCCGCACACGGACAGAACATCTTTCAGAACAGCACAAGGGCAAGGTCAAAGGCTGTAAGACACCTTTGCAGTCC TTCCTGGGAATCGCTGAGCAGCACGGGGGCCCCCAAAATGGGACCCTGATCACTCAGACTCTGAGCCAAGCCAACCCCACTGCCATCACT GCAGAAGAATACTTCAACCCCAACTTTGAGCTGGGCAACCGTGATATGGGCCGCCCCATGGAACTGACCACCAAGACACAGAAGTTCAAG GCCAAGCTGTGGCTGTGTGAGGAGCATCCCCTGTCCCTGTGTGAGCAGGTGGCCCCCATCATTGACCTCATGGCCGTCAGCAATGCGCTT TTTGCCAAGCTCCGGGACTTCATCACCCTGCGTCTGCCTCCTGGCTTCCCAGTTAAGATTGAAATCCCGATCTTCCACATCCTCAACGCC CGCATCACCTTCGGGAACCTCAACGGCTGCGACGAACCGGTGCCATCGGTGCGAGGCAGCCCCAGCAGCGAGACGCCTTCCCCAGGCAGC GACTCCTCCAGCGTCAGCAGCTCCAGCTCCACGACCTCCTGCCGCGGCTGCGAGATCTCCCCAGCGTTGTTCGAGGCCCCGCGCGGCTAC AGCATGATGGGCGGCCAGCGGGAGGCGGCGACCCGGGACGACGACGACGACCTGCTGCAATTCGCCATCCAGCAGAGCCTGCTTGAGGCG GGCAGTGAGTATGACCAGGTCACCATCTGGGAGGCGCTAACCAACAGCAAGCCAGGCACCCACCCCATGTCCTACGAGGGTCGCCGACAG GACAGGAGCGCCCCGCCCACGCCGCAGCGCCAGCCTGCGCCCCCGGCGTCAGTGCCCAGCCCTCGGCCCAGCTCAGGGCCAGGTTCCGGC GGCCACGTGTTCCGGAGCTACGACGAGCAGCTGCGGCTGGCGATGGAACTGTCGGCGCAGGAGCAGGAGGAGAGGCGGCGGCGCGCGCGC CAGGAGGAGGAGGAGCTGGAGCGCATCCTGAGGCTCTCACTGACCGAGCAGTAGCGCCCCCTGCCGGGACCCTCGCCAGCGCCACGCGCG CCACGCCCAGGGCCAGGAGCCAGACAAACCCCGGCCTGCGCGCCTGCAGAGCGGCGGCTGGAGACTGGAGCCACCGCCTCGCGGGTGCAG CAGCACAGCAGGCACGGTTCGGGGAGGGATTCGGCATGGCCGCGGGGTACCTTCCCAGGCCAGGGCCCTGGAGGCAACTGGCACGGCCTG GTCCCCCTGCTTTGCTGTATTCTGATTCCCCAACCCGCTCCCCTGGGCTCAGATCTGTCCTGTCCTAGGGCGGAGCCAGGCGGTCCTGAG GGGGAGATGAATCCTTAGAGGAGCGCTGTCCCTATCCCTTGCTCCTTCTGGCCGGTCCGCATTTCTGTTCACTAACCCCACTCCAGGACA CTGCCCCTGAAGCCTTTGCATCTCTGCTCTTCACTCCTGGGGGGCAGCTGAGCTCCCCGCGTGCTGTGTCACTGCTTTGTTCCAGACACA AACCAGCACGTCTAGGGCCCAGCCCCTCCCCCACCCCGGCATTTCAGCGTCAAGTGCACTTAGCGGGGTACCCGGCTCCCCCAGCCCCCA CACCCGTCCTGGGTCTCAGGGTGGTTCCAGCTTCTCCTTGGGCAGCCAGAAGTTGGAGTCCCATCCCCCAAGGCACATTTTTTTTTTTTT TTTTTTGTGATCAGGGAGTGTGTCCAACGTAGCCCCCTGGCCTGTGCAAGCCCTGACTCCCTCATGGTGCCTCGGAGAGTGGGGAGCATA TTGGGCTGGGGTAAGCACTAGACCCAAGTAGACTGGACACAAAGGGCTCGCCCAGGGCCCTGGCGCCACCCCCACCCCTTCCCACCAGCT GCTGCTAGCCTCTGTGGTTGTACATCCCACTTGCCCCCACACGGAGACTGACTCTAAAACCCTTCATCCAATGGTGCTAACCCCCGGCTC TCCCCTGCCCCACCTCACCCACCCAGAGAAGCACAGACCCCGCCAGGGGCAGGGGCCCACCGCACACCCTTGTCCCGGGCCTGTCTGGGA CTGGCCTTCCCGGCTCAGCCAGTGAGGCTCAGAAGGGACACAAAGAGGGATGGAAGAAAAGAACAAAGAGAAACTGTTCCTCCCACCCCC >In-frame_NSRP1_ENST00000247026_chr17_28445191_+_ANKRD13B_ENST00000394859_chr17_27934760_+_3123nt CGTGACGACATCGGCGTCAGCGTCACGGAGGCGTCGGCCACGTTCAGCGGACACGGGAGCAAGATGGCGATTCCGGGCAGGCAGTATGGG CTTATTTTGCCAAAGAAAACACAGCAGTTGCACCCTGTTTTGCAAAAACCATCAGTGTTTGGGAATGATTCTGATGATGATGATGAGGTG GACATCGAGCAGCTGGATCCCCGCGGCCGGACTCCCCTGCACCTGGCCACCACGCTGGGGCACCTTGAGTGTGCCCGTGTGCTCCTGGCG CACGGCGCAGACGTGGGCAGGGAGAATCGCAGCGGCTGGACAGTGCTCCAGGAGGCTGTGAGTACCCGGGACCTGGAGCTGGTGCAGCTG GTGCTTCGGTACCGGGACTACCAGCGGGTGGTGAAGCGGCTGGCGGGCATCCCCGTGCTCCTGGAGAAGCTGCGCAAGGCCCAGGACTTC TACGTGGAGATGAAATGGGAGTTCACTAGCTGGGTGCCCCTGGTGTCCAAGATCTGCCCTAGTGACACCTACAAAGTGTGGAAGAGCGGC CAGAACCTGAGGGTAGACACCACACTCCTGGGCTTTGACCACATGACCTGGCAGCGAGGGAACCGCAGCTTTGTCTTCAGGGGCCAAGAC ACAAGCGCCGTGGTCATGGAGATTGACCACGACCGCCGGGTGGTGTACACAGAGACTCTGGCACTGGCTGGGCAGGACCGGGAGCTGCTG CTGGCTGCTGCTCAGCCCACTGAGGAACAGGTGCTGAGCCGGCTTACCGCGCCCGTCGTCACCACTCAGCTTGACACCAAGAATATCTCC TTTGAGAGGAACAAGACTGGCATCCTGGGCTGGCGCAGTGAAAAGACGGAGATGGTGAATGGGTATGAAGCTAAGGTGTATGGGGCATCT AACGTGGAGCTCATCACCCGCACACGGACAGAACATCTTTCAGAACAGCACAAGGGCAAGGTCAAAGGCTGTAAGACACCTTTGCAGTCC TTCCTGGGAATCGCTGAGCAGCACGGGGGCCCCCAAAATGGGACCCTGATCACTCAGACTCTGAGCCAAGCCAACCCCACTGCCATCACT GCAGAAGAATACTTCAACCCCAACTTTGAGCTGGGCAACCGTGATATGGGCCGCCCCATGGAACTGACCACCAAGACACAGAAGTTCAAG GCCAAGCTGTGGCTGTGTGAGGAGCATCCCCTGTCCCTGTGTGAGCAGGTGGCCCCCATCATTGACCTCATGGCCGTCAGCAATGCGCTT TTTGCCAAGCTCCGGGACTTCATCACCCTGCGTCTGCCTCCTGGCTTCCCAGTTAAGATTGAAATCCCGATCTTCCACATCCTCAACGCC CGCATCACCTTCGGGAACCTCAACGGCTGCGACGAACCGGTGCCATCGGTGCGAGGCAGCCCCAGCAGCGAGACGCCTTCCCCAGGCAGC GACTCCTCCAGCGTCAGCAGCTCCAGCTCCACGACCTCCTGCCGCGGCTGCGAGATCTCCCCAGCGTTGTTCGAGGCCCCGCGCGGCTAC AGCATGATGGGCGGCCAGCGGGAGGCGGCGACCCGGGACGACGACGACGACCTGCTGCAATTCGCCATCCAGCAGAGCCTGCTTGAGGCG GGCAGTGAGTATGACCAGGTCACCATCTGGGAGGCGCTAACCAACAGCAAGCCAGGCACCCACCCCATGTCCTACGAGGGTCGCCGACAG GACAGGAGCGCCCCGCCCACGCCGCAGCGCCAGCCTGCGCCCCCGGCGTCAGTGCCCAGCCCTCGGCCCAGCTCAGGGCCAGGTTCCGGC GGCCACGTGTTCCGGAGCTACGACGAGCAGCTGCGGCTGGCGATGGAACTGTCGGCGCAGGAGCAGGAGGAGAGGCGGCGGCGCGCGCGC CAGGAGGAGGAGGAGCTGGAGCGCATCCTGAGGCTCTCACTGACCGAGCAGTAGCGCCCCCTGCCGGGACCCTCGCCAGCGCCACGCGCG CCACGCCCAGGGCCAGGAGCCAGACAAACCCCGGCCTGCGCGCCTGCAGAGCGGCGGCTGGAGACTGGAGCCACCGCCTCGCGGGTGCAG CAGCACAGCAGGCACGGTTCGGGGAGGGATTCGGCATGGCCGCGGGGTACCTTCCCAGGCCAGGGCCCTGGAGGCAACTGGCACGGCCTG GTCCCCCTGCTTTGCTGTATTCTGATTCCCCAACCCGCTCCCCTGGGCTCAGATCTGTCCTGTCCTAGGGCGGAGCCAGGCGGTCCTGAG GGGGAGATGAATCCTTAGAGGAGCGCTGTCCCTATCCCTTGCTCCTTCTGGCCGGTCCGCATTTCTGTTCACTAACCCCACTCCAGGACA CTGCCCCTGAAGCCTTTGCATCTCTGCTCTTCACTCCTGGGGGGCAGCTGAGCTCCCCGCGTGCTGTGTCACTGCTTTGTTCCAGACACA AACCAGCACGTCTAGGGCCCAGCCCCTCCCCCACCCCGGCATTTCAGCGTCAAGTGCACTTAGCGGGGTACCCGGCTCCCCCAGCCCCCA CACCCGTCCTGGGTCTCAGGGTGGTTCCAGCTTCTCCTTGGGCAGCCAGAAGTTGGAGTCCCATCCCCCAAGGCACATTTTTTTTTTTTT TTTTTTGTGATCAGGGAGTGTGTCCAACGTAGCCCCCTGGCCTGTGCAAGCCCTGACTCCCTCATGGTGCCTCGGAGAGTGGGGAGCATA TTGGGCTGGGGTAAGCACTAGACCCAAGTAGACTGGACACAAAGGGCTCGCCCAGGGCCCTGGCGCCACCCCCACCCCTTCCCACCAGCT GCTGCTAGCCTCTGTGGTTGTACATCCCACTTGCCCCCACACGGAGACTGACTCTAAAACCCTTCATCCAATGGTGCTAACCCCCGGCTC TCCCCTGCCCCACCTCACCCACCCAGAGAAGCACAGACCCCGCCAGGGGCAGGGGCCCACCGCACACCCTTGTCCCGGGCCTGTCTGGGA CTGGCCTTCCCGGCTCAGCCAGTGAGGCTCAGAAGGGACACAAAGAGGGATGGAAGAAAAGAACAAAGAGAAACTGTTCCTCCCACCCCC |
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FusionGenePPI for NSRP1_ANKRD13B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NSRP1 | NEDD4L, NEDD4, JMJD6, APP, BARD1, CTNNBL1, FBXO25, CDK18, SRPK2, SRPK1, CIAO1, HIST1H3E, MYO1C, XRCC3, EMC2, CHORDC1, MMGT1 | ANKRD13B | RPLP1, EGFR, UBC, GNAI3, PSMD4, HDAC1, BOD1L1, VCP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NSRP1_ANKRD13B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NSRP1_ANKRD13B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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