|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 24899 |
FusionGeneSummary for NSD1_C11orf58 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NSD1_C11orf58 | Fusion gene ID: 24899 | Hgene | Tgene | Gene symbol | NSD1 | C11orf58 | Gene ID | 64324 | 10944 |
| Gene name | nuclear receptor binding SET domain protein 1 | chromosome 11 open reading frame 58 | |
| Synonyms | ARA267|KMT3B|SOTOS|SOTOS1|STO | IMAGE145052|SMAP | |
| Cytomap | 5q35.3 | 11p15.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specificH3-K36-HMTaseH4-K20-HMTaseNR-binding SET domain-containing proteinandrogen receptor coactivator 267 kDa proteinandrogen receptor-associated coregulator 267androgen receptor-as | small acidic protein | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q96L73 | ||
| Ensembl transtripts involved in fusion gene | ENST00000354179, ENST00000439151, ENST00000347982, ENST00000361032, ENST00000511258, | ENST00000228136, ENST00000422258, ENST00000527893, ENST00000525684, | |
| Fusion gene scores | * DoF score | 17 X 10 X 13=2210 | 3 X 3 X 2=18 |
| # samples | 20 | 3 | |
| ** MAII score | log2(20/2210*10)=-3.46597446450407 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NSD1 [Title/Abstract] AND C11orf58 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NSD1 | GO:0045893 | positive regulation of transcription, DNA-templated | 11509567 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-85-A50M-01A | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000354179 | ENST00000228136 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-5UTR | ENST00000354179 | ENST00000422258 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000354179 | ENST00000527893 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000354179 | ENST00000525684 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| In-frame | ENST00000439151 | ENST00000228136 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-5UTR | ENST00000439151 | ENST00000422258 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000439151 | ENST00000527893 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000439151 | ENST00000525684 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| In-frame | ENST00000347982 | ENST00000228136 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-5UTR | ENST00000347982 | ENST00000422258 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000347982 | ENST00000527893 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000347982 | ENST00000525684 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| In-frame | ENST00000361032 | ENST00000228136 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-5UTR | ENST00000361032 | ENST00000422258 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000361032 | ENST00000527893 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| 5CDS-3UTR | ENST00000361032 | ENST00000525684 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| intron-3CDS | ENST00000511258 | ENST00000228136 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| intron-5UTR | ENST00000511258 | ENST00000422258 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| intron-3UTR | ENST00000511258 | ENST00000527893 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
| intron-3UTR | ENST00000511258 | ENST00000525684 | NSD1 | chr5 | 176666866 | + | C11orf58 | chr11 | 16766148 | + |
Top |
FusionProtFeatures for NSD1_C11orf58 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NSD1 | C11orf58 |
| Histone methyltransferase. Preferentially methylates'Lys-36' of histone H3 and 'Lys-20' of histone H4 (in vitro).Transcriptional intermediary factor capable of both negatively orpositively influencing transcription, depending on the cellularcontext. {ECO:0000269|PubMed:21196496}. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 323_388 | 1165 | 2428 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 323_388 | 1165 | 2428 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 323_388 | 1331 | 2594 | Domain | PWWP 1 |
| Hgene | NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 323_388 | 1434 | 2697 | Domain | PWWP 1 |
| Tgene | >C11orf58 | chr5:176666866 | chr11:16766148 | ENST00000228136 | + | 0 | 5 | 109_139 | 21 | 184 | Compositional bias | Note=Asp-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 2207_2421 | 1165 | 2428 | Compositional bias | Note=Pro-rich |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 2207_2421 | 1165 | 2428 | Compositional bias | Note=Pro-rich |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 2207_2421 | 1331 | 2594 | Compositional bias | Note=Pro-rich |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 2207_2421 | 1434 | 2697 | Compositional bias | Note=Pro-rich |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1756_1818 | 1165 | 2428 | Domain | PWWP 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1890_1940 | 1165 | 2428 | Domain | AWS |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1942_2059 | 1165 | 2428 | Domain | SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 2066_2082 | 1165 | 2428 | Domain | Post-SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1756_1818 | 1165 | 2428 | Domain | PWWP 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1890_1940 | 1165 | 2428 | Domain | AWS |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1942_2059 | 1165 | 2428 | Domain | SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 2066_2082 | 1165 | 2428 | Domain | Post-SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1756_1818 | 1331 | 2594 | Domain | PWWP 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1890_1940 | 1331 | 2594 | Domain | AWS |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1942_2059 | 1331 | 2594 | Domain | SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 2066_2082 | 1331 | 2594 | Domain | Post-SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1756_1818 | 1434 | 2697 | Domain | PWWP 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1890_1940 | 1434 | 2697 | Domain | AWS |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1942_2059 | 1434 | 2697 | Domain | SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 2066_2082 | 1434 | 2697 | Domain | Post-SET |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1952_1954 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1994_1997 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 2020_2021 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 2060_2066 | 1165 | 2428 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1952_1954 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1994_1997 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 2020_2021 | 1165 | 2428 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 2060_2066 | 1165 | 2428 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1952_1954 | 1331 | 2594 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1994_1997 | 1331 | 2594 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 2020_2021 | 1331 | 2594 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 2060_2066 | 1331 | 2594 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1952_1954 | 1434 | 2697 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1994_1997 | 1434 | 2697 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 2020_2021 | 1434 | 2697 | Region | Note=S-adenosyl-L-methionine binding |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 2060_2066 | 1434 | 2697 | Region | Note=Inhibits enzyme activity in the absence of bound histone |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1543_1589 | 1165 | 2428 | Zinc finger | PHD-type 1 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1590_1646 | 1165 | 2428 | Zinc finger | PHD-type 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 1707_1751 | 1165 | 2428 | Zinc finger | PHD-type 3 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000347982 | + | 9 | 24 | 2118_2165 | 1165 | 2428 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1543_1589 | 1165 | 2428 | Zinc finger | PHD-type 1 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1590_1646 | 1165 | 2428 | Zinc finger | PHD-type 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 1707_1751 | 1165 | 2428 | Zinc finger | PHD-type 3 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000354179 | + | 9 | 24 | 2118_2165 | 1165 | 2428 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1543_1589 | 1331 | 2594 | Zinc finger | PHD-type 1 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1590_1646 | 1331 | 2594 | Zinc finger | PHD-type 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 1707_1751 | 1331 | 2594 | Zinc finger | PHD-type 3 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000361032 | + | 5 | 20 | 2118_2165 | 1331 | 2594 | Zinc finger | PHD-type 4%3B atypical |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1543_1589 | 1434 | 2697 | Zinc finger | PHD-type 1 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1590_1646 | 1434 | 2697 | Zinc finger | PHD-type 2 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 1707_1751 | 1434 | 2697 | Zinc finger | PHD-type 3 |
| Hgene | >NSD1 | chr5:176666866 | chr11:16766148 | ENST00000439151 | + | 8 | 23 | 2118_2165 | 1434 | 2697 | Zinc finger | PHD-type 4%3B atypical |
Top |
FusionGeneSequence for NSD1_C11orf58 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NSD1_ENST00000354179_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_1328aa MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRR PYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKL DSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFIS GDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDE EKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSA EPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEE CSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHI PIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSG ELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLR GGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTK PRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQ AELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREA PFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKLGSSN WEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDV >In-frame_NSD1_ENST00000439151_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_1597aa MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRRP YRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLD SEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISG DISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEE KRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAE PGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEEC SLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIP IEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGE LSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRG GAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKP RKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQA ELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAP FLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKLGSSNW EAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVA >In-frame_NSD1_ENST00000347982_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_1328aa MPLKTRTALSDDPDSSTSTLGNMLELPGTSSSSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVSNRR PYRQYYVEAFGDPSERAWVAGKAIVMFEGRHQFEELPVLRRRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKL DSEEDMPFEDCTNDPESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFIS GDISDTQASNELSRIANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDE EKRSDSISICTTSDDGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSA EPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEE CSLKCCSSDTKGSPLASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHI PIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSG ELSASLPGLLSDKRDLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLR GGAEDPSKEDPLQIMGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTK PRKRMNRFKEKENSECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQ AELPEPAVRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREA PFLEGPLAQSELGGGHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKLGSSN WEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDV >In-frame_NSD1_ENST00000361032_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_1494aa MDQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGS ADGSESFQDPEKSDSRAQTPIVCTSLSPGGPTALAMKQEPSCNNSPELQVKVTKTIKNGFLHFENFTCVDDADVDSEMDPEQPVTEDESI EEIFEETQTNATCNYETKSENGVKVAMGSEQDSTPESRHGAVKSPFLPLAPQTETQKNKQRNEVDGSNEKAALLPAPFSLGDTNITIEEQ LNSINLSFQDDPDSSTSTLGNMLELPGTSSSSTSQELPFVPQKILSKWEASVGLAEQYDVPKGSKNRKCIPGSIKLDSEEDMPFEDCTND PESEHDLLLNGCLKSLAFDSEHSADEKEKPCAKSRARKSSDNPKRTSVKKGHIQFEAHKDERRGKIPENLGLNFISGDISDTQASNELSR IANSLTGSNTAPGSFLFSSCGKNTAKKEFETSNGDSLLGLPEGALISKCSREKNKPQRSLVCGSKVKLCYIGAGDEEKRSDSISICTTSD DGSSDLDPIEHSSESDNSVLEIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLISNSHTDHLMGCTKSAEPGTETSQVNLSDL KASTLVHKPQSDFTNDALSPKFNLSSSISSENSLIKGGAANQALLHSKSKQPKFRSIKCKHKENPVMAEPPVINEECSLKCCSSDTKGSP LASISKSGKVDGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRSLGEDVSDSGTSKPSKPLLFSSASSQNHIPIEPDYKFSTLLMM LKDMHDSKTKEQRLMTAQNLVSYRSPGRGDCSTNSPVGVSKVLVSGGSTHNSEKKGDGTQNSANPSPSGGDSALSGELSASLPGLLSDKR DLPASGKSRSDCVTRRNCGRSKPSSKLRDAFSAQMVKNTVNRKALKTERKRKLNQLPSVTLDAVLQGDRERGGSLRGGAEDPSKEDPLQI MGHLTSEDGDHFSDVHFDSKVKQSDPGKISEKGLSFENGKGPELDSVMNSENDELNGVNQVVPKKRWQRLNQRRTKPRKRMNRFKEKENS ECAFRVLLPSDPVQEGRDEFPEHRTPSASILEEPLTEQNHADCLDSAGPRLNVCDKSSASIGDMEKEPGIPSLTPQAELPEPAVRSEKKR LRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEEESLLARGRSSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSELGG GHAELPQLTLSVPVAPEVSPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSKKLGSSNWEAADLGNEERKQK FLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NSD1_ENST00000354179_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_3984nt ATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCA TCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCA AAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGG CCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGA CATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGT AAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTG GACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTG GCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACT AGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCT GGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTG TTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATC TCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAG GAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGAT AACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTT GCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCA GAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGAT GCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACAT TCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAG TGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTG AACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTAC AGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATA CCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACT GCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGA GGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGC GAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGC AACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAG ACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGA GGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCAT TTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCT GTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAA CCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGG CGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCA GCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAG GCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGAT CAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCC CGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCT CCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCG GAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACT AAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAAT TGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAGTTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTT GTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGGGAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAA AGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGTGGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTG GCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCTGAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAA TCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTGGAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATG >In-frame_NSD1_ENST00000439151_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_4791nt ATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGC CCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGGTGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCT TATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTACAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCT GCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCAAGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGT CCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCCCCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTT CTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGATTCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATA GAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTATGAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAA CAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCATTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAA AGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCAGCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAA TTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCA TCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAA TTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCC TATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACAT CAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAA TGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGAC AGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCT TTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGT GTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGG GATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTT TCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCA AAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAA AAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAAC AGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCT GCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAG CCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCT CTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCG AAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGC AGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAAC AATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGA TCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCT ATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCT CAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGC TCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAG TTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAAC TGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACC GAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGT GGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTC GATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTA ATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCT CGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGG GATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCT GGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCT GAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAG ATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGA GGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCG TTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAA GTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAG AAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAATTGG GAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAGTTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTTGTT ATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGGGAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAAAGT ATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGTGGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTGGCT GGAGATGATGATGATGACGATGATGATTCACCTGATCCTGAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAATCT GCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTGGAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATGTTT >In-frame_NSD1_ENST00000347982_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_3984nt ATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCA TCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCA AAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGG CCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGA CATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGT AAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTG GACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTG GCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACT AGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCT GGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTG TTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATC TCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAG GAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGAT AACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTT GCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCA GAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGAT GCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACAT TCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAG TGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTG AACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTAC AGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATA CCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACT GCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGA GGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGC GAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGC AACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAG ACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGA GGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCAT TTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCT GTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAA CCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGG CGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCA GCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAG GCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGAT CAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCC CGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCT CCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCG GAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACT AAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAAT TGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAGTTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTT GTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGGGAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAA AGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGTGGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTG GCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCTGAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAA TCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTGGAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATG >In-frame_NSD1_ENST00000361032_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_4482nt ATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGC CCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGGTGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCT TATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTACAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCT GCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCAAGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGT CCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCCCCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTT CTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGATTCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATA GAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTATGAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAA CAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCATTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAA AGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCAGCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAA TTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCA TCATCTACTTCACAGGAATTGCCATTTGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTT CCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGAT CCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCT TGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGAT GAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGG ATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAG ACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTG GTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGAT GATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAG AACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTC ATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTG AAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGT GAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAA CACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCT TTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAA ACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAG CCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATG TTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGAC TGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAG AACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGA GACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCT TTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACT CTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATA ATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCT GAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAA GTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCT GAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATA CTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGC ATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGC CTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAG CAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAAT TCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGT GGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTA GTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATG CCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAATTGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAG TTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTTGTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGG GAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAAAGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGT GGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTGGCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCT GAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAATCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NSD1_ENST00000354179_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_5263nt GGCCGGGTAGGGGGTTCGCCTGCGGCCGCGTCTGCTCGGGGCCTGAGGCCTCGAAGACCCCAGCCCAAGCCCCCAGGTTGATGCCGGCCC AGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGAC AGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGA ATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATG GTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGT GGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACC TGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGG ACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCC ATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTC TGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACAT ACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCA GGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAA CACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAA GAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCAT TAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCC AGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGT AAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTC TCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAA CCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAA GTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTC TTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAAC CAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGT CAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAA ATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTA CCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGA GAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACC TGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCC TTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACT GAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAG TAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCA ATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGA TGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAG ATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCA TAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGT TTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGC TGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAA AAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCA GAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTT GGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGC CCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAA TGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAATTGGGAGGCAGCAGACTTGGG TAATGAAGAGAGAAAACAAAAGTTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTTGTTATAGGAGATCACAAATC AACATCTCACTTCCGAACCGGGGAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAAAGTATGGACAGTAAATTATC AGGAAGATATCGGCGACATTGTGGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTGGCTGGAGATGATGATGATGA CGATGATGATTCACCTGATCCTGAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAATCTGCTGAAGAACTCCAAGC TGCTGAGCACCCTGATGAAGTGGAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATGTTTGTTAAATCCAGTGGTTC ATAACTCCCAAACGCTTAGTCTTTGTATTAAAAGTAAGCCTTATTGTTACAATGCACAGTGGAGGACTGCTTATAGAGCACAGACCTTTG TATTATAATTTTTAAAAAGGCCCTTTTAAATAATTACAAAGAGTGTTTGCTTTCAAATGCCATGGGTTACACTTTTATGGGCATGACTAT AACCATTTTTGTAAAGAGTAAGAGTTGTATAAAATAAGAAATAAATACAGTACTCAACTTCCTTTCATATTAGCATCATCAACCCTCTAA TTCACCTTATGGGGGAAATGCTTCTTTTTGTTTGTGATAGCTATTTTATCATTTCCTTCATATTTTTCTCTTATAAAAATGTATTTGATA CTGTGATATGTTCACGAAAAGTATTCTTTAATTATTCTTTGTTATAGTAGAGCTGTTCATTATGGATATTTCTGCTGCCAGTCACAATCT AAATTAATTTTGGCAAAAGATTGGGTACTTAGTTTCCTGTTACTGAGTTAGCTCTACTCTTTTGGACCAAAGCAACATGAGAGCAAGTAC TTTTCACACTTGTTAAGATGGAGTTATAACTGTCATACATTTGGAATATTATGATCCCAAGTAGTCTTTTTATAATTTGGATTGTATCGT ATGTTAGATTTTTGATAAAATTTGGCCAATTTTTACAGAAGAAATTCTCTGATCATTTAGTTCTGTCTATTTAGAAATATGTAAAACTGG ATTTTTTTTTAAGTAATATGTGACCAAAGTTAATTTTGTCCCAAAGGTCTAAATAAAGAGCAGTTTCCCATATTTGGCTGTGATACCTTT ATCCTCATTATCTACAAATGAGGAACAGGCTTACTGATAAGAAGCTGAAACAAGAAATTCTCTTCATTTTATCCCAGTGCTATTTTATTG ATTAATTACTAAAAAGTATTACTTTCTAATTTTATTGCTGTTTCTGTTGGTGTGAGATTAGAATCATCTGACTGCTATTAGGTGGTTGAT TTGTATAGCTGATTAACACAAATTGCATTATGAGCTAGTAAATGGATCTTTGGATAATGGGGTCCAAATTCTTAATGTTTATAAGTAACA >In-frame_NSD1_ENST00000439151_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_5955nt GCTGGCCCGGGAGGGGGCGCGGGGCACGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCC TTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGG TGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCTTATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTA CAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCTGCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCA AGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGTCCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCC CCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTTCTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGAT TCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATAGAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTAT GAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAACAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCA TTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAAAGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCA GCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAATTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGT ACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAG TCTACGCCACTGAAGTATGAAGTTGGAGATCTCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCG TTGATTAACACACATTCAAAAATGAAAGTTTCCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGA GCCTGGGTGGCTGGAAAAGCAATCGTCATGTTTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAA GAAAAAGGATATAGGCATAAGGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAG GGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAG TCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCT AAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGG AGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCA AATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCA AATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGT GGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGA AGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATG TTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGT AACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCA TCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAAC TCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAA GAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCC AGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCA GTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCA AAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAA GATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCT ACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCC GCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTC CCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCA GCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGAT GCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGC CACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAA GGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTG CCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGT GCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAG GAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGT GACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGG AAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTG CACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTG ATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACAT GCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAA ACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAG AAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAATTGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAGTTCTTG AGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTTGTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGGGAAGAA GACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAAAGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGTGGACTT GGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTGGCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCTGAAAGT CCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAATCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTGGAGGAT CCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATGTTTGTTAAATCCAGTGGTTCATAACTCCCAAACGCTTAGTCTTTGTAT TAAAAGTAAGCCTTATTGTTACAATGCACAGTGGAGGACTGCTTATAGAGCACAGACCTTTGTATTATAATTTTTAAAAAGGCCCTTTTA AATAATTACAAAGAGTGTTTGCTTTCAAATGCCATGGGTTACACTTTTATGGGCATGACTATAACCATTTTTGTAAAGAGTAAGAGTTGT ATAAAATAAGAAATAAATACAGTACTCAACTTCCTTTCATATTAGCATCATCAACCCTCTAATTCACCTTATGGGGGAAATGCTTCTTTT TGTTTGTGATAGCTATTTTATCATTTCCTTCATATTTTTCTCTTATAAAAATGTATTTGATACTGTGATATGTTCACGAAAAGTATTCTT TAATTATTCTTTGTTATAGTAGAGCTGTTCATTATGGATATTTCTGCTGCCAGTCACAATCTAAATTAATTTTGGCAAAAGATTGGGTAC TTAGTTTCCTGTTACTGAGTTAGCTCTACTCTTTTGGACCAAAGCAACATGAGAGCAAGTACTTTTCACACTTGTTAAGATGGAGTTATA ACTGTCATACATTTGGAATATTATGATCCCAAGTAGTCTTTTTATAATTTGGATTGTATCGTATGTTAGATTTTTGATAAAATTTGGCCA ATTTTTACAGAAGAAATTCTCTGATCATTTAGTTCTGTCTATTTAGAAATATGTAAAACTGGATTTTTTTTTAAGTAATATGTGACCAAA GTTAATTTTGTCCCAAAGGTCTAAATAAAGAGCAGTTTCCCATATTTGGCTGTGATACCTTTATCCTCATTATCTACAAATGAGGAACAG GCTTACTGATAAGAAGCTGAAACAAGAAATTCTCTTCATTTTATCCCAGTGCTATTTTATTGATTAATTACTAAAAAGTATTACTTTCTA ATTTTATTGCTGTTTCTGTTGGTGTGAGATTAGAATCATCTGACTGCTATTAGGTGGTTGATTTGTATAGCTGATTAACACAAATTGCAT TATGAGCTAGTAAATGGATCTTTGGATAATGGGGTCCAAATTCTTAATGTTTATAAGTAACAAGTTCAAAGGCTTTAGTCACACCTGTTT >In-frame_NSD1_ENST00000347982_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_5204nt CCTCCGCCTCCCCTCAGGTTGATGCCGGCCCAGGATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCC AGTGAATTTAGATGCCCCTGAAGACAAGGACAGCCCTTTCGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTAC CTGGAACTTCATCATCATCTACTTCACAGGAATTGCCATTTTGTCAACCTAAGAAAAAGTCTACGCCACTGAAGTATGAAGTTGGAGATC TCATCTGGGCAAAATTCAAGAGACGCCCATGGTGGCCCTGCAGGATTTGTTCTGATCCGTTGATTAACACACATTCAAAAATGAAAGTTT CCAACCGGAGGCCCTATCGGCAGTACTACGTGGAGGCTTTTGGAGATCCTTCTGAGAGAGCCTGGGTGGCTGGAAAAGCAATCGTCATGT TTGAAGGCAGACATCAATTCGAAGAGCTACCTGTCCTTAGGAGAAGAGGGAAACAGAAAGAAAAAGGATATAGGCATAAGGTTCCTCAGA AAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTTCCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTT CAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGATCCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTT TGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCTTGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATC CAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGATGAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAA ACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGGATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAG GAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAGACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGG GTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTGGTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAG CAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGATGATGGAAGCAGTGACCTGGATCCCATAGAACACAGCT CAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAGAACATGTTATCTATGCAGAAAAATGAAAAGATAAAGT ATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTCATTAGTAACTCACATACAGACCACTTAATGGGTTGTA CTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTGAAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATT TTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGTGAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAG CTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAACACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTA TAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCTTTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTC TAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAAACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGG AACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAGCCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTC AGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATGTTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGC GGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGACTGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTT TGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAGAACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTG CATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGAGACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTG TTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCTTTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTA AAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACTCTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAG GTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATAATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTT CTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCTGAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAG AGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAAGTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAA GGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCTGAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTG TGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATACTTGAGGAACCACTGACAGAGCAAAATCATGCTGACT GCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGCATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTT TGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGCCTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAG AAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAGCAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAA GCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAATTCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTG AAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGTGGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGC CTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTAGTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAA GAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATGCCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGG GATCTAGCAATTGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAGTTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATA CTGGTCGTCTTGTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGGGAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTC AATATCAGCAAAGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGTGGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAG AAGGTGATGTGGCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCTGAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAG AGAAAGAAGAATCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTGGAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATT ATAAAATGATGTTTGTTAAATCCAGTGGTTCATAACTCCCAAACGCTTAGTCTTTGTATTAAAAGTAAGCCTTATTGTTACAATGCACAG TGGAGGACTGCTTATAGAGCACAGACCTTTGTATTATAATTTTTAAAAAGGCCCTTTTAAATAATTACAAAGAGTGTTTGCTTTCAAATG CCATGGGTTACACTTTTATGGGCATGACTATAACCATTTTTGTAAAGAGTAAGAGTTGTATAAAATAAGAAATAAATACAGTACTCAACT TCCTTTCATATTAGCATCATCAACCCTCTAATTCACCTTATGGGGGAAATGCTTCTTTTTGTTTGTGATAGCTATTTTATCATTTCCTTC ATATTTTTCTCTTATAAAAATGTATTTGATACTGTGATATGTTCACGAAAAGTATTCTTTAATTATTCTTTGTTATAGTAGAGCTGTTCA TTATGGATATTTCTGCTGCCAGTCACAATCTAAATTAATTTTGGCAAAAGATTGGGTACTTAGTTTCCTGTTACTGAGTTAGCTCTACTC TTTTGGACCAAAGCAACATGAGAGCAAGTACTTTTCACACTTGTTAAGATGGAGTTATAACTGTCATACATTTGGAATATTATGATCCCA AGTAGTCTTTTTATAATTTGGATTGTATCGTATGTTAGATTTTTGATAAAATTTGGCCAATTTTTACAGAAGAAATTCTCTGATCATTTA GTTCTGTCTATTTAGAAATATGTAAAACTGGATTTTTTTTTAAGTAATATGTGACCAAAGTTAATTTTGTCCCAAAGGTCTAAATAAAGA GCAGTTTCCCATATTTGGCTGTGATACCTTTATCCTCATTATCTACAAATGAGGAACAGGCTTACTGATAAGAAGCTGAAACAAGAAATT CTCTTCATTTTATCCCAGTGCTATTTTATTGATTAATTACTAAAAAGTATTACTTTCTAATTTTATTGCTGTTTCTGTTGGTGTGAGATT AGAATCATCTGACTGCTATTAGGTGGTTGATTTGTATAGCTGATTAACACAAATTGCATTATGAGCTAGTAAATGGATCTTTGGATAATG >In-frame_NSD1_ENST00000361032_chr5_176666866_+_C11orf58_ENST00000228136_chr11_16766148_+_5601nt ATGGATCAGACCTGTGAACTACCCAGAAGAAATTGTCTGCTGCCCTTTTCCAATCCAGTGAATTTAGATGCCCCTGAAGACAAGGACAGC CCTTTCGGTAATGGTCAATCCAATTTTTCTGAGCCACTTAATGGGTGTACTATGCAGTTATCGACTGTCAGTGGAACATCCCAAAATGCT TATGGACAAGATTCTCCATCTTGTTACATTCCACTGCGGAGACTACAGGATTTGGCCTCCATGATCAATGTAGAGTATTTAAATGGGTCT GCTGATGGATCAGAATCCTTTCAAGACCCTGAAAAAAGTGATTCAAGAGCTCAGACGCCAATTGTTTGCACTTCCTTGAGTCCTGGTGGT CCTACAGCACTTGCTATGAAACAGGAACCCTCTTGTAATAACTCCCCTGAACTCCAGGTAAAAGTAACAAAGACTATCAAGAATGGCTTT CTGCACTTTGAGAATTTTACTTGTGTGGACGATGCAGATGTAGATTCTGAAATGGACCCAGAACAGCCAGTCACAGAGGATGAGAGTATA GAGGAGATCTTTGAGGAAACTCAGACCAATGCCACCTGCAATTATGAGACTAAATCAGAGAATGGTGTAAAAGTGGCCATGGGAAGTGAA CAAGACAGCACACCAGAGAGTAGACACGGTGCAGTCAAATCGCCATTCTTGCCATTAGCTCCTCAGACTGAAACACAGAAAAATAAGCAA AGAAATGAAGTGGACGGCAGCAATGAAAAAGCAGCCCTTCTCCCAGCCCCCTTTTCACTAGGAGACACAAACATTACAATAGAAGAGCAA TTAAACTCAATAAATTTATCTTTTCAGGATGATCCAGATTCCAGTACCAGTACATTAGGAAACATGCTAGAATTACCTGGAACTTCATCA TCATCTACTTCACAGGAATTGCCATTTGTTCCTCAGAAAATTTTGAGTAAATGGGAAGCCAGTGTTGGACTTGCAGAACAGTATGATGTT CCCAAGGGGTCAAAGAACCGAAAATGTATTCCTGGTTCAATCAAGTTGGACAGTGAAGAAGATATGCCATTTGAAGACTGCACAAATGAT CCTGAGTCAGAACATGACCTGTTGCTTAATGGCTGTTTGAAATCACTGGCTTTTGATTCTGAACATTCTGCAGATGAGAAGGAAAAGCCT TGCGCTAAATCTCGAGCCAGAAAGAGCTCTGATAATCCAAAAAGGACTAGTGTGAAAAAGGGCCACATACAATTTGAAGCACATAAAGAT GAACGGAGGGGAAAGATTCCAGAGAACCTTGGCCTAAACTTTATCTCTGGGGATATATCTGATACGCAGGCCTCTAATGAACTTTCCAGG ATAGCAAATAGCCTCACAGGGTCCAACACTGCCCCAGGAAGTTTTCTGTTTTCTTCCTGTGGAAAAAACACTGCAAAGAAAGAATTTGAG ACTTCAAATGGTGACTCTTTATTGGGCTTGCCTGAGGGTGCTTTGATCTCAAAGTGTTCTCGAGAGAAGAATAAACCCCAACGAAGCCTG GTGTGTGGTTCAAAAGTGAAGCTCTGCTATATTGGAGCAGGTGATGAGGAAAAGCGAAGTGATTCCATTAGTATCTGTACCACTTCTGAT GATGGAAGCAGTGACCTGGATCCCATAGAACACAGCTCAGAGTCTGATAACAGTGTCCTTGAAATTCCAGATGCTTTCGATAGAACAGAG AACATGTTATCTATGCAGAAAAATGAAAAGATAAAGTATTCTAGGTTTGCTGCCACAAACACTAGGGTAAAAGCAAAACAGAAGCCTCTC ATTAGTAACTCACATACAGACCACTTAATGGGTTGTACTAAGAGTGCAGAGCCTGGAACCGAGACGTCTCAGGTTAATCTCTCTGATCTG AAGGCATCTACTCTTGTTCACAAACCCCAGTCAGATTTTACAAATGATGCTCTCTCTCCAAAATTCAACCTGTCATCAAGCATATCCAGT GAGAACTCGTTAATAAAGGGTGGGGCAGCAAATCAAGCTCTATTACATTCGAAAAGCAAACAGCCCAAGTTCCGAAGTATAAAGTGCAAA CACAAAGAAAATCCAGTTATGGCAGAACCCCCAGTTATAAATGAGGAGTGCAGTTTGAAATGCTGCTCTTCTGATACCAAAGGCTCTCCT TTGGCCAGCATTTCTAAAAGTGGGAAAGTGGATGGTCTAAAACTACTGAACAATATGCATGAGAAAACCAGGGATTCAAGTGACATAGAA ACAGCAGTGGTGAAACATGTTTTATCCGAGTTGAAGGAACTCTCTTACAGATCCTTAGGTGAGGATGTCAGTGACTCTGGAACATCAAAG CCATCAAAACCATTACTTTTCTCTTCTGCTTCTAGTCAGAATCACATACCTATTGAACCAGACTACAAATTCAGTACATTGCTAATGATG TTGAAAGATATGCATGATAGTAAGACGAAGGAGCAGCGGTTGATGACTGCTCAAAACCTGGTCTCTTACCGGAGTCCTGGTCGTGGGGAC TGTTCTACTAATAGTCCTGTAGGAGTCTCTAAGGTTTTGGTTTCAGGAGGCTCCACACACAATTCAGAGAAAAAGGGAGATGGCACTCAG AACTCCGCCAATCCTAGCCCTAGTGGGGGTGACTCTGCATTATCTGGCGAGTTGTCTGCTTCCCTACCTGGCTTACTGTCCGACAAGAGA GACCTCCCTGCTTCTGGTAAAAGTCGTTCAGACTGTGTTACTAGGCGCAACTGTGGACGATCAAAGCCTTCATCCAAATTGCGAGATGCT TTTTCAGCCCAAATGGTAAAGAACACAGTGAACCGTAAAGCCTTAAAGACCGAGCGCAAAAGAAAACTGAATCAGCTTCCAAGTGTGACT CTTGATGCTGTACTGCAGGGAGACCGAGAACGTGGAGGTTCATTGAGAGGTGGGGCAGAAGATCCTAGTAAAGAGGATCCCCTTCAGATA ATGGGCCACTTAACAAGTGAAGATGGTGACCATTTTTCTGATGTGCATTTCGATAGCAAGGTTAAGCAATCTGATCCTGGTAAAATTTCT GAAAAAGGACTCTCTTTTGAAAACGGAAAAGGCCCAGAGCTGGACTCTGTAATGAACAGTGAGAATGATGAACTCAATGGTGTAAATCAA GTGGTGCCTAAAAAGCGGTGGCAGCGTTTAAACCAAAGGCGCACTAAACCTCGTAAGCGCATGAACAGATTTAAAGAGAAAGAAAACTCT GAGTGTGCCTTTAGGGTCTTACTTCCTAGTGACCCTGTGCAGGAGGGGCGGGATGAGTTTCCAGAGCATAGAACTCCTTCAGCAAGCATA CTTGAGGAACCACTGACAGAGCAAAATCATGCTGACTGCTTAGATTCAGCTGGGCCACGGTTAAATGTTTGTGATAAATCCAGTGCCAGC ATTGGTGACATGGAAAAGGAGCCAGGAATTCCCAGTTTGACACCACAGGCTGAGCTCCCTGAACCAGCTGTGCGGTCAGAGAAGAAACGC CTTAGGAAGCCAAGCAAGTGGCTTTTGGAATATACAGAAGAATATGATCAGATATTTGCTCCTAAGAAAAAACAAAAGAAGGTACAGGAG CAGGTGCACAAGGTAAGTTCCCGCTGTGAAGAGGAAAGCCTTCTAGCCCGAGGTCGATCTAGTGCTCAGAACAAGCAGGTGGACGAGAAT TCTTTGATTTCAACCAAAGAAGAGCCTCCAGTTCTTGAAAGGGAGGCTCCGTTTTTGGAGGGCCCCTTGGCTCAGTCAGAACTTGGAGGT GGACATGCTGAGTTGCCGCAGCTGACCTTGTCTGTGCCTGTGGCTCCGGAAGTCTCTCCACGGCCTGCCCTTGAGTCTGAGGAATTGCTA GTTAAAACGCCAGGAAATTATGAAAGTAAACGTCAAAGAAAACCAACTAAGAAACTTCTTGAATCCAATGATTTAGACCCTGGATTTATG CCCAAGAAGGGGGACCTTGGCCTTTCTAAAAAGCTGGGATCTAGCAATTGGGAGGCAGCAGACTTGGGTAATGAAGAGAGAAAACAAAAG TTCTTGAGACTTATGGGTGCAGGAAAGAAAGAACATACTGGTCGTCTTGTTATAGGAGATCACAAATCAACATCTCACTTCCGAACCGGG GAAGAAGACAAGAAAATTAATGAAGAACTGGAGTCTCAATATCAGCAAAGTATGGACAGTAAATTATCAGGAAGATATCGGCGACATTGT GGACTTGGCTTCAGTGAGGTAGAAGACCATGATGGAGAAGGTGATGTGGCTGGAGATGATGATGATGACGATGATGATTCACCTGATCCT GAAAGTCCAGATGATTCTGAAAGCGATTCAGAGTCAGAGAAAGAAGAATCTGCTGAAGAACTCCAAGCTGCTGAGCACCCTGATGAAGTG GAGGATCCCAAAAACAAAAAAGATGCAAAAAGCAATTATAAAATGATGTTTGTTAAATCCAGTGGTTCATAACTCCCAAACGCTTAGTCT TTGTATTAAAAGTAAGCCTTATTGTTACAATGCACAGTGGAGGACTGCTTATAGAGCACAGACCTTTGTATTATAATTTTTAAAAAGGCC CTTTTAAATAATTACAAAGAGTGTTTGCTTTCAAATGCCATGGGTTACACTTTTATGGGCATGACTATAACCATTTTTGTAAAGAGTAAG AGTTGTATAAAATAAGAAATAAATACAGTACTCAACTTCCTTTCATATTAGCATCATCAACCCTCTAATTCACCTTATGGGGGAAATGCT TCTTTTTGTTTGTGATAGCTATTTTATCATTTCCTTCATATTTTTCTCTTATAAAAATGTATTTGATACTGTGATATGTTCACGAAAAGT ATTCTTTAATTATTCTTTGTTATAGTAGAGCTGTTCATTATGGATATTTCTGCTGCCAGTCACAATCTAAATTAATTTTGGCAAAAGATT GGGTACTTAGTTTCCTGTTACTGAGTTAGCTCTACTCTTTTGGACCAAAGCAACATGAGAGCAAGTACTTTTCACACTTGTTAAGATGGA GTTATAACTGTCATACATTTGGAATATTATGATCCCAAGTAGTCTTTTTATAATTTGGATTGTATCGTATGTTAGATTTTTGATAAAATT TGGCCAATTTTTACAGAAGAAATTCTCTGATCATTTAGTTCTGTCTATTTAGAAATATGTAAAACTGGATTTTTTTTTAAGTAATATGTG ACCAAAGTTAATTTTGTCCCAAAGGTCTAAATAAAGAGCAGTTTCCCATATTTGGCTGTGATACCTTTATCCTCATTATCTACAAATGAG GAACAGGCTTACTGATAAGAAGCTGAAACAAGAAATTCTCTTCATTTTATCCCAGTGCTATTTTATTGATTAATTACTAAAAAGTATTAC TTTCTAATTTTATTGCTGTTTCTGTTGGTGTGAGATTAGAATCATCTGACTGCTATTAGGTGGTTGATTTGTATAGCTGATTAACACAAA TTGCATTATGAGCTAGTAAATGGATCTTTGGATAATGGGGTCCAAATTCTTAATGTTTATAAGTAACAAGTTCAAAGGCTTTAGTCACAC |
Top |
FusionGenePPI for NSD1_C11orf58 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NSD1 | ZNF496, AR, RELA, AFF1, SIRT7, HIST4H4, TNFRSF21, RARA, RXRA, ESR1, PPARG, VDR, THRB, RORA, RORB, HNF4G, NR2F6, ESRRA, NR5A2, NR6A1, NR2F1, NR2F2, NR2E1, HIST3H3, HIST1H1B, ATRX, SNORD3A, HIST1H1D, HIST1H1C, GAR1, HIST1H3A, HIST1H4A, POLR2A, ZFY, ZBTB48, ZNF692, MECP2, TRIM25 | C11orf58 | MARK2, WDR48, ZBTB48, TRA2A, SF3B1, A2M, KIAA1377, EEF1G, FBN3, POLR2C, SHC1, SLC44A1, RPLP1, SEMA5B, RNF19A, SNCAIP, MBTPS1, PTN, AHCYL1, PRDX6, SET, PSMB7, CCNT1, PSMB2, RCN1, MYL6B, BZW2, CHORDC1, HSPD1, KYNU, LDHA, SCRN1, GDA, GNS, NAGK, OXCT1, SMS, SUGT1, WDR1, KPNB1, RANGAP1, HMGN5, HYPK, NAP1L1, PTMA, EWSR1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for NSD1_C11orf58 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for NSD1_C11orf58 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NSD1 | C0175695 | Sotos' syndrome | 14 | CTD_human;ORPHANET;UNIPROT |
| Hgene | NSD1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Hgene | NSD1 | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Hgene | NSD1 | C0265210 | Weaver syndrome | 1 | CTD_human;ORPHANET |
| Hgene | NSD1 | C3714756 | Intellectual Disability | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|