FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 24195

FusionGeneSummary for NFE2L2_PDE11A

check button Fusion gene summary
Fusion gene informationFusion gene name: NFE2L2_PDE11A
Fusion gene ID: 24195
HgeneTgene
Gene symbol

NFE2L2

PDE11A

Gene ID

4780

50940

Gene namenuclear factor, erythroid 2 like 2phosphodiesterase 11A
SynonymsHEBP1|IMDDHH|NRF2PPNAD2
Cytomap

2q31.2

2q31.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear factor erythroid 2-related factor 2nuclear factor erythroid-derived 2-like 2dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AcAMP and cGMP cyclic nucleotide phosphodiesterase 11A
Modification date2018052720180329
UniProtAcc

Q16236

Q9HCR9

Ensembl transtripts involved in fusion geneENST00000397063, ENST00000397062, 
ENST00000446151, ENST00000464747, 
ENST00000423513, 
ENST00000286063, 
ENST00000358450, ENST00000450799, 
ENST00000409504, ENST00000389683, 
ENST00000449286, ENST00000497003, 
Fusion gene scores* DoF score15 X 14 X 7=14708 X 4 X 6=192
# samples 218
** MAII scorelog2(21/1470*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(8/192*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NFE2L2 [Title/Abstract] AND PDE11A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneNFE2L2

GO:0010499

proteasomal ubiquitin-independent protein catabolic process

19424503

HgeneNFE2L2

GO:0016567

protein ubiquitination

15983046

HgeneNFE2L2

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

15983046

HgeneNFE2L2

GO:0045944

positive regulation of transcription by RNA polymerase II

17015834

HgeneNFE2L2

GO:0071498

cellular response to fluid shear stress

25190803


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-18-4721-01ANFE2L2chr2

178097120

-PDE11Achr2

178634101

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000397063ENST00000286063NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
Frame-shitENST00000397063ENST00000358450NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397063ENST00000450799NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397063ENST00000409504NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397063ENST00000389683NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397063ENST00000449286NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-5UTRENST00000397063ENST00000497003NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
In-frameENST00000397062ENST00000286063NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
In-frameENST00000397062ENST00000358450NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397062ENST00000450799NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397062ENST00000409504NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397062ENST00000389683NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000397062ENST00000449286NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-5UTRENST00000397062ENST00000497003NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
Frame-shitENST00000446151ENST00000286063NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
Frame-shitENST00000446151ENST00000358450NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000446151ENST00000450799NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000446151ENST00000409504NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000446151ENST00000389683NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000446151ENST00000449286NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-5UTRENST00000446151ENST00000497003NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
Frame-shitENST00000464747ENST00000286063NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
Frame-shitENST00000464747ENST00000358450NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000464747ENST00000450799NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000464747ENST00000409504NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000464747ENST00000389683NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-intronENST00000464747ENST00000449286NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
5CDS-5UTRENST00000464747ENST00000497003NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-3CDSENST00000423513ENST00000286063NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-3CDSENST00000423513ENST00000358450NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-intronENST00000423513ENST00000450799NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-intronENST00000423513ENST00000409504NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-intronENST00000423513ENST00000389683NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-intronENST00000423513ENST00000449286NFE2L2chr2

178097120

-PDE11Achr2

178634101

-
intron-5UTRENST00000423513ENST00000497003NFE2L2chr2

178097120

-PDE11Achr2

178634101

-

Top

FusionProtFeatures for NFE2L2_PDE11A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
NFE2L2

Q16236

PDE11A

Q9HCR9

Transcription activator that binds to antioxidantresponse (ARE) elements in the promoter regions of target genes.Important for the coordinated up-regulation of genes in responseto oxidative stress and the regulation of cellular redoxconditions. May be involved in the transcriptional activation ofgenes of the beta-globin cluster by mediating enhancer activity ofhypersensitive site 2 of the beta-globin locus control region.{ECO:0000269|PubMed:11035812, ECO:0000269|PubMed:29018201}. Plays a role in signal transduction by regulating theintracellular concentration of cyclic nucleotides cAMP and cGMP.Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively. {ECO:0000269|PubMed:10725373,ECO:0000269|PubMed:10906126, ECO:0000269|PubMed:11050148}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for NFE2L2_PDE11A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000286063_chr2_178634101_-_553aa
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKETELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQ
HIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGM
QQDIEQVWEELLSIPELQVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWL
LTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHA
VMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVA
ELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLTQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS

>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000358450_chr2_178634101_-_553aa
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKETELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQ
HIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGM
QQDIEQVWEELLSIPELQVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDTETLCRWL
LTVRKNTRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLTGTSATLEHHHFNHA
VMILQSEGHNIFANLSSKETSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVA
ELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLTQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000286063_chr2_178634101_-_1659nt
ATGATGGACTTGGAGCTGCCGCCGCCGGGACTCCCGTCCCAGCAGGACATGGATTTGATTGACATACTTTGGAGGCAAGATATAGATCTT
GGAGTAAGTCGAGAAGTATTTGACTTCAGTCAGCGACGGAAAGAGTATGAGCTGGAAAAACAGAAAAAACTTGAAAAGGAAAGACAAGAA
CAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGTTACAACTAGATGAAGAGACAGGTGAATTTCTCCCAATTCAGCCAGCCCAG
CACATCCAGTCAGAAACCAGTGGATCTGCCAACTACTCCCAGGTTGCCCACATTCCCAAATCAGATGCTTTGTACTTTGATGACTGCATG
CAGCTTTTGGCGCAGACATTCCCGTTTGTAGATGACAATGAGGTTTCTTCGGCTACGTTTCAGTCACTTGTTCCTGATATTCCCGGTCAC
ATCGAGAGCCCAGTCTTCATTGCTACTAATCAGGCTCAGTCACCTGAAACTTCTGTTGCTCAGGTAGCCCCTGTTGATTTAGACGGTATG
CAACAGGACATTGAGCAAGTTTGGGAGGAGCTATTATCCATTCCTGAGTTACAGGTGCTATCATACCATGCAACATGTTCAAAAGCTGAA
GTTGACAAGTTTAAGGCAGCCAACATCCCTCTGGTGTCAGAACTTGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGAT
GCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTT
TTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGGAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACC
ACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACC
AACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTCTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCC
GTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTGTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCA
ATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAA
AACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCA
GAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGG
AAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTG
AAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCC

>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000358450_chr2_178634101_-_1659nt
ATGATGGACTTGGAGCTGCCGCCGCCGGGACTCCCGTCCCAGCAGGACATGGATTTGATTGACATACTTTGGAGGCAAGATATAGATCTT
GGAGTAAGTCGAGAAGTATTTGACTTCAGTCAGCGACGGAAAGAGTATGAGCTGGAAAAACAGAAAAAACTTGAAAAGGAAAGACAAGAA
CAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGTTACAACTAGATGAAGAGACAGGTGAATTTCTCCCAATTCAGCCAGCCCAG
CACATCCAGTCAGAAACCAGTGGATCTGCCAACTACTCCCAGGTTGCCCACATTCCCAAATCAGATGCTTTGTACTTTGATGACTGCATG
CAGCTTTTGGCGCAGACATTCCCGTTTGTAGATGACAATGAGGTTTCTTCGGCTACGTTTCAGTCACTTGTTCCTGATATTCCCGGTCAC
ATCGAGAGCCCAGTCTTCATTGCTACTAATCAGGCTCAGTCACCTGAAACTTCTGTTGCTCAGGTAGCCCCTGTTGATTTAGACGGTATG
CAACAGGACATTGAGCAAGTTTGGGAGGAGCTATTATCCATTCCTGAGTTACAGGTGCTATCATACCATGCAACATGTTCAAAAGCTGAA
GTTGACAAGTTTAAGGCAGCCAACATCCCTCTGGTGTCAGAACTTGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGAT
GCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTT
TTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGGAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACC
ACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACC
AACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTCTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCC
GTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTGTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCA
ATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAA
AACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCA
GAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGG
AAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTG
AAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000286063_chr2_178634101_-_8369nt
AAATCAGGGAGGCGCAGCTCCTACACCAACGCCTTTCCGGGGCTCCGGGTGTGTTTGTTCCAACTGTTTAAACTGTTTCAAAGCGTCCGA
ACTCCAGCGACCTTCGCAAACAACTCTTTATCTCGCGGGCGAGAGCGCTGCCCTTATTTGCGGGGGAGGGCAAACTGAACGCCGGCACCG
GGGAGCTAACGGAGACCTCCTCTAGGTCCCCCGCCTGCTGGGACCCCAGCTGGCAGTCCCTTCCCGCCCCCGGACCGCGAGCTTCTTGCG
TCAGCCCCGGCGCGGGTGGGGGATTTTCGGAAGCTCAGCCCGCGCGGCCGGCGGGGGAAGGAAGGGCCCGGACTCTTGCCCCGCCCTTGT
GGGGCGGGAGGCGGAGCGGGGCAGGGGCCCGCCGGCGTGTAGCCGATTACCGAGTGCCGGGGAGCCCGGAGGAGCCGCCGACGCAGCCGC
CACCGCCGCCGCCGCCGCCACCAGAGCCGCCCTGTCCGCGCCGCGCCTCGGCAGCCGGAACAGGGCCGCCGTCGGGGAGCCCCAACACAC
GGTCCACAGCTCATCATGATGGACTTGGAGCTGCCGCCGCCGGGACTCCCGTCCCAGCAGGACATGGATTTGATTGACATACTTTGGAGG
CAAGATATAGATCTTGGAGTAAGTCGAGAAGTATTTGACTTCAGTCAGCGACGGAAAGAGTATGAGCTGGAAAAACAGAAAAAACTTGAA
AAGGAAAGACAAGAACAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGTTACAACTAGATGAAGAGACAGGTGAATTTCTCCCA
ATTCAGCCAGCCCAGCACATCCAGTCAGAAACCAGTGGATCTGCCAACTACTCCCAGGTTGCCCACATTCCCAAATCAGATGCTTTGTAC
TTTGATGACTGCATGCAGCTTTTGGCGCAGACATTCCCGTTTGTAGATGACAATGAGGTTTCTTCGGCTACGTTTCAGTCACTTGTTCCT
GATATTCCCGGTCACATCGAGAGCCCAGTCTTCATTGCTACTAATCAGGCTCAGTCACCTGAAACTTCTGTTGCTCAGGTAGCCCCTGTT
GATTTAGACGGTATGCAACAGGACATTGAGCAAGTTTGGGAGGAGCTATTATCCATTCCTGAGTTACAGGTGCTATCATACCATGCAACA
TGTTCAAAAGCTGAAGTTGACAAGTTTAAGGCAGCCAACATCCCTCTGGTGTCAGAACTTGCCATCGATGACATTCATTTTGATGACTTT
TCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATTGACTATGAGACA
CTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGGAGACATGCCTTCAACGTGTGTCAGCTGATG
TTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTC
GACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTCTATGGAACCTCTGCTACCTTGGAGCATCAC
CATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTGTCCTCCAAGGAATATAGTGACCTTATGCAG
CTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATAC
GATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATC
TCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCAGCAATT
TTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATGCCTTTGTATCAGGCACTGGTGAAG
GTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCA
ACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTCCAGGTCAGCTGCAGCTGCAAAATGACTACAG
CCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGACCTAACATCTCAAGGATGCACTGGGAAGCAT
GCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAGAAAGAGGTGGGGCAGGGAGCACACCCCAGGA
CCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACTGTTTTGGATCCAAGGACCTGTGGACAGTCGG
CCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCGTTTTGTATAGGGCTTTTCTGTTTGTTACAAG
CCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCCAAGAATCCTAATTTGTATTCCATAGAGGTAT
TTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAGGTAAACTATACTATCCTTATAAATACTGATC
AATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGATGGGTAATTCTAGACTGGGACTATGGTACCCT
TTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATGGATTGATAGATTTTGATTAAAGTAAGGGTGG
AAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGACAGAGCAGAGCCATGGAGACTAAGCATTGACT
ACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACCAACTTAAAGCAAACTATAGGGGTCCCTAATT
TTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGGGCAAAGAACGCATATTCTATAGGAAGCCAGG
TTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTGCTCCCTATATTGAGAAATTGTGGACATGGTA
TGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTATTGACTGGATTGACTTGAACAAGTCACTTAA
CTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGAACATGTTTTAACCTTACAACTCTTTGTTCAA
ATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGAATTATAAGCAGGGTTTGGACATCCAGAGCAC
CTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTTTGAAAATCCCTGGCCTAGATTAAACCTGAGA
GCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTTTGTTTCTTTGTTTGTTTGTTTTTTGAGACTG
AGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAACCTCTGCTTCCTGGGTTCAAGCAATTCTCCAG
CCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTTGTACTTTTAGTAGACACAGGGTTTCACCATG
TTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAAAGTGCTGGGATTACAGGCGTGAGCCACCGTA
CCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGAAATAGGGGCCATGTTCTACATGCGACATTGT
TTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAAGATACCAAAATGGAATTGAGGGGAGAGCAGG
TAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACCGGGCGCGGTGGCTCACGCCTGTAATCCCAGC
AATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAAAAC
ACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAAGAGAATGGCGGGAACCCGCGAGG
CGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAACGTAAGAACACCAGTAAAGGAAAGACAGGGA
CCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAACAAAGAAAAATGGCACTTCCAACCAAAAAAA
ATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAGGGGTTTGAGAAAGGGGAGAAGGAAGGAGTGA
GAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTGGAGAAAGTAGAGGGGGAAATGAATGCAGGAA
GAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAGCCAGTTTTCTGTATCACTCTGCTATAAAGGA
AAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAGTCAGGGACAGAGTCTGGTCTGCGAGATCGTG
ACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTTATATCACGAACGGGAATTGAAAATCAGTCTG
TGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGCCCAGACAAATGGATGCCAGTCCATCTACAGC
AACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCAGGCTGCCGTGAGCACTGTAGCTATCCTGAAC
ATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCCACTAAGGTTGAGTTTTCCTCTCATTTTCTTG
CCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGAGTTCAACACCATTGCAATCTGCCATACAGTG
GAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTTCTCCTGTCTTGAGGTATCTTTCCTATTGTGG
GTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGCAGTGGACAGGAAGGTAGCAGCTTCCTGGTGC
CAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTTTTCTAAACAATTTATAATTTTGCAAGAATGT
GAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCCAGTCCTTATTATTAATGTTTATTTCCTATTG
GAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTTTGCTTCCTCAGGTCTCTTGGCATTAATTGTT
GAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTTACTAGTCACTATGTAGCTATTATGTGCACAA
TCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGCCATTCAGTGCATAGCAGACTGGAACTCCCTC
CTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCATCTATTACATAAAAGCACTGACTTTTATTCA
GTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTTCTTTTTTATTCTTCTCAAATAAAATAGCAAC
AAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAGATGTAAGCACAATCATACTACAGATGTATCT
TGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATATGTCCTTTTTTTGAGACAGGGTCTTGCTCTG
TCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAACTTAAGTGATCTTTCCTGCCTCAGCCTCATGA
GTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAAGACGAGGCCTCACTATGCTGACCACACTGGT
CTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAGAGATATGAACCACCACACCCACCTTATATGT
CCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATGGTAGTCATTAATTTAGAAGTGAATTTATAAA
GTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCATTTCCAGGTATTGTATATTTGCAAATACATT
GGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTAATGCTGCCAGAATCCAGTTGCTTTTTCTGTG
TATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCCAATTTATTCTGCAGTAAAATTATTTTAAAAT
CTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAGTAATAGTGTGAAACAATTTCCTTCCAGTGGG
ACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAAAAAAAAAAAAACCACCAAAACACAAAAAGGA
TTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCACTGTAATGAAGTTTCATTATCTGCTTCAGAGT
AACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATGTATCAGGAAATGTAAAGGTTAAGTCTGACTA
CAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAGAGGGCAGAAATAAAATGAGGTGTATCTGGAG
AATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTCATGACCTTGTCTTCAGCTAGTAATTTGGGGT
TGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACTGCTAAAGATAAATTGTTTATCTGTATAACAT
AACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTAATGAAGTATTTGCTGTGAAAAATGTATTATT
TGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATCTCAATTTTTCTTTTACTCTAGTTTAGATTAA
GACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGAGTCTCATTCCCTTGGGGGGAAATTGCTTTTG
CCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAATTATTATTGTTTTACACGAAAGAAAGGAAATA
CGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTTTCATTGTAAGAATATTACATTATAGACAGGT

>In-frame_NFE2L2_ENST00000397062_chr2_178097120_-_PDE11A_ENST00000358450_chr2_178634101_-_3552nt
AAATCAGGGAGGCGCAGCTCCTACACCAACGCCTTTCCGGGGCTCCGGGTGTGTTTGTTCCAACTGTTTAAACTGTTTCAAAGCGTCCGA
ACTCCAGCGACCTTCGCAAACAACTCTTTATCTCGCGGGCGAGAGCGCTGCCCTTATTTGCGGGGGAGGGCAAACTGAACGCCGGCACCG
GGGAGCTAACGGAGACCTCCTCTAGGTCCCCCGCCTGCTGGGACCCCAGCTGGCAGTCCCTTCCCGCCCCCGGACCGCGAGCTTCTTGCG
TCAGCCCCGGCGCGGGTGGGGGATTTTCGGAAGCTCAGCCCGCGCGGCCGGCGGGGGAAGGAAGGGCCCGGACTCTTGCCCCGCCCTTGT
GGGGCGGGAGGCGGAGCGGGGCAGGGGCCCGCCGGCGTGTAGCCGATTACCGAGTGCCGGGGAGCCCGGAGGAGCCGCCGACGCAGCCGC
CACCGCCGCCGCCGCCGCCACCAGAGCCGCCCTGTCCGCGCCGCGCCTCGGCAGCCGGAACAGGGCCGCCGTCGGGGAGCCCCAACACAC
GGTCCACAGCTCATCATGATGGACTTGGAGCTGCCGCCGCCGGGACTCCCGTCCCAGCAGGACATGGATTTGATTGACATACTTTGGAGG
CAAGATATAGATCTTGGAGTAAGTCGAGAAGTATTTGACTTCAGTCAGCGACGGAAAGAGTATGAGCTGGAAAAACAGAAAAAACTTGAA
AAGGAAAGACAAGAACAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGTTACAACTAGATGAAGAGACAGGTGAATTTCTCCCA
ATTCAGCCAGCCCAGCACATCCAGTCAGAAACCAGTGGATCTGCCAACTACTCCCAGGTTGCCCACATTCCCAAATCAGATGCTTTGTAC
TTTGATGACTGCATGCAGCTTTTGGCGCAGACATTCCCGTTTGTAGATGACAATGAGGTTTCTTCGGCTACGTTTCAGTCACTTGTTCCT
GATATTCCCGGTCACATCGAGAGCCCAGTCTTCATTGCTACTAATCAGGCTCAGTCACCTGAAACTTCTGTTGCTCAGGTAGCCCCTGTT
GATTTAGACGGTATGCAACAGGACATTGAGCAAGTTTGGGAGGAGCTATTATCCATTCCTGAGTTACAGGTGCTATCATACCATGCAACA
TGTTCAAAAGCTGAAGTTGACAAGTTTAAGGCAGCCAACATCCCTCTGGTGTCAGAACTTGCCATCGATGACATTCATTTTGATGACTTT
TCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGATGGTACAGAAATTTAAAATTGACTATGAGACA
CTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTGGAGACATGCCTTCAACGTGTGTCAGCTGATG
TTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGCGGTGATTGTGGGATGCCTGTGTCATGACCTC
GACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACTCTATGGAACCTCTGCTACCTTGGAGCATCAC
CATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCTGTCCTCCAAGGAATATAGTGACCTTATGCAG
CTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGAATTCTTTGAACTTGTCAGTAAAGGAGAATAC
GATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGACCTTGGAGCCGTGACCAAACCGTGGGAGATC
TCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAGATTAGAGCTCAAACTCACTCCTTCAGCAATT
TTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCATCTGCATGCCTTTGTATCAGGCACTGGTGAAG
GTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGAAGAGCTACACCAAAAACGACTGCTGGCCTCA
ACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTCCAGGTCAGCTGCAGCTGCAAAATGACTACAG
CCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGACCTAACATCTCAAGGATGCACTGGGAAGCAT
GCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAGAAAGAGGTGGGGCAGGGAGCACACCCCAGGA
CCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACTGTTTTGGATCCAAGGACCTGTGGACAGTCGG
CCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCGTTTTGTATAGGGCTTTTCTGTTTGTTACAAG
CCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCCAAGAATCCTAATTTGTATTCCATAGAGGTAT
TTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAGGTAAACTATACTATCCTTATAAATACTGATC
AATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGATGGGTAATTCTAGACTGGGACTATGGTACCCT
TTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATGGATTGATAGATTTTGATTAAAGTAAGGGTGG
AAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGACAGAGCAGAGCCATGGAGACTAAGCATTGACT
ACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACCAACTTAAAGCAAACTATAGGGGTCCCTAATT
TTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGGGCAAAGAACGCATATTCTATAGGAAGCCAGG
TTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTGCTCCCTATATTGAGAAATTGTGGACATGGTA
TGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTATTGACTGGATTGACTTGAACAAGTCACTTAA
CTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGAACATGTTTTAACCTTACAACTCTTTGTTCAA


Top

FusionGenePPI for NFE2L2_PDE11A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
NFE2L2CREBBP, PMF1, EIF2AK3, KEAP1, MAFK, MAFF, JUN, TRIM24, SMARCA4, CUL3, NCOR2, NCOR1, YY1, MYC, BACH1, PRKCD, PRKCA, PRKCQ, PRKCH, PRKCG, SQSTM1, GADD45GIP1, CDKN1A, GSK3B, PGAM5, UBE2E3, UBE2E2, COPS7A, ENC1, MAFG, BPTF, SUMO1, SUMO2, RNF4, SIAH2, NFE2L3, NFE2, ATF4, CREB3, AHR, KPNA3, RBMX, NQO1, BRCA1, AKT1, MAPK8, MAPK9, MAP2K1, MAP2K2, MAPK7, HDAC1, HDAC2, HDAC3, FBXW11, TNNT1, WAC, TCF20, UBC, BTRC, TRIM28, RBM45, MAF, CDH1, PAQR3, PPP1R13L, DCAF11PDE11A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for NFE2L2_PDE11A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgenePDE11AQ9HCR9DB00820TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Asmall moleculeapproved|investigational

Top

RelatedDiseases for NFE2L2_PDE11A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNFE2L2C4277682Chemical and Drug Induced Liver Injury4CTD_human
HgeneNFE2L2C0007131Non-Small Cell Lung Carcinoma2CTD_human
HgeneNFE2L2C0033578Prostatic Neoplasms2CTD_human
HgeneNFE2L2C0007137Squamous cell carcinoma1CTD_human
HgeneNFE2L2C0008370Cholestasis1CTD_human
HgeneNFE2L2C0011881Diabetic Nephropathy1CTD_human
HgeneNFE2L2C0013990Pathological accumulation of air in tissues1CTD_human
HgeneNFE2L2C0014072Experimental Autoimmune Encephalomyelitis1CTD_human
HgeneNFE2L2C0014170Endometrial Neoplasms1CTD_human
HgeneNFE2L2C0017178Gastrointestinal Diseases1CTD_human
HgeneNFE2L2C0020456Hyperglycemia1CTD_human
HgeneNFE2L2C0020507Hyperplasia1CTD_human
HgeneNFE2L2C0022593Keratosis1CTD_human
HgeneNFE2L2C0022658Kidney Diseases1CTD_human
HgeneNFE2L2C0023890Liver Cirrhosis1CTD_human
HgeneNFE2L2C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneNFE2L2C0023903Liver neoplasms1CTD_human
HgeneNFE2L2C0027540Necrosis1CTD_human
HgeneNFE2L2C0034069Pulmonary Fibrosis1CTD_human
HgeneNFE2L2C0037286Skin Neoplasms1CTD_human
HgeneNFE2L2C0041755Adverse reaction to drug1CTD_human
HgeneNFE2L2C0085215Ovarian Failure, Premature1CTD_human
HgeneNFE2L2C0162820Dermatitis, Allergic Contact1CTD_human
HgeneNFE2L2C0235032Neurotoxicity Syndromes1CTD_human
HgeneNFE2L2C0242488Acute Lung Injury1CTD_human
HgeneNFE2L2C0279626Squamous cell carcinoma of esophagus1CTD_human
HgeneNFE2L2C0400966Non-alcoholic Fatty Liver Disease1CTD_human
HgeneNFE2L2C0887833Carcinoma, Pancreatic Ductal1CTD_human
HgeneNFE2L2C2239176Liver carcinoma1CTD_human
HgeneNFE2L2C2609414Acute kidney injury1CTD_human
TgenePDE11AC0041696Unipolar Depression1PSYGENET
TgenePDE11AC1269683Major Depressive Disorder1PSYGENET