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Fusion gene ID: 24162 |
FusionGeneSummary for NFATC2IP_KIAA0556 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NFATC2IP_KIAA0556 | Fusion gene ID: 24162 | Hgene | Tgene | Gene symbol | NFATC2IP | KIAA0556 | Gene ID | 84901 | 23247 |
| Gene name | nuclear factor of activated T cells 2 interacting protein | KIAA0556 | |
| Synonyms | ESC2|NIP45|RAD60 | JBTS26 | |
| Cytomap | 16p11.2 | 16p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | NFATC2-interacting protein45 kDa NF-AT-interacting protein45 kDa NFAT-interacting proteinnuclear factor of activated T-cells, cytoplasmic 2-interacting proteinnuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protei | protein KIAA0556Katanin-interacting proteinKatnip | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8NCF5 | O60303 | |
| Ensembl transtripts involved in fusion gene | ENST00000564978, ENST00000320805, ENST00000562977, ENST00000568148, | ENST00000261588, ENST00000567894, | |
| Fusion gene scores | * DoF score | 3 X 2 X 2=12 | 2 X 2 X 2=8 |
| # samples | 3 | 2 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: NFATC2IP [Title/Abstract] AND KIAA0556 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | DDR (DNA damage repair) gene involved fusion gene, retained protein feature but frameshift. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-X6-A8C2-01A | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000564978 | ENST00000261588 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| 5CDS-intron | ENST00000564978 | ENST00000567894 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| In-frame | ENST00000320805 | ENST00000261588 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| 5CDS-intron | ENST00000320805 | ENST00000567894 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| 3UTR-3CDS | ENST00000562977 | ENST00000261588 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| 3UTR-intron | ENST00000562977 | ENST00000567894 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| intron-3CDS | ENST00000568148 | ENST00000261588 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
| intron-intron | ENST00000568148 | ENST00000567894 | NFATC2IP | chr16 | 28963525 | + | KIAA0556 | chr16 | 27760905 | + |
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FusionProtFeatures for NFATC2IP_KIAA0556 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NFATC2IP | KIAA0556 |
| In T-helper 2 (Th2) cells, regulates the magnitude ofNFAT-driven transcription of a specific subset of cytokine genes,including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 tothe IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at theIL4 locus, thus promotes robust cytokine expression (Bysimilarity). Down-regulates formation of poly-SUMO chains byUBE2I/UBC9 (By similarity). {ECO:0000250}. | May influence the stability of microtubules (MT),possibly through interaction with the MT-severing katanin complex.{ECO:0000269|PubMed:26714646}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NFATC2IP_KIAA0556 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NFATC2IP_ENST00000320805_chr16_28963525_+_KIAA0556_ENST00000261588_chr16_27760905_+_898aa MAEPVGKRGRWSGGSGAGRGGRGGWGGRGRRPRAQRSPSRGTLDVVSVDLVTDSDEEILEVATARGAADEVEVEPPEPPGPVASRDNSNS DSEGEDRRPAGPPREPVRRRRRLVLDPGEAPLVPVYSGKVKSSLRLIPDDLSLLKLYPPGDEEEDTWSSRTPSRSRWRSEQEHTLHESWS SLSAFDRSHRGRISNTELPGDILDELLQQKSSRHSDLPPSKKGEQPGLSRGQDGYSGETDAGGDFKIPVLPYGQRLVIDIKSTWGDRHYV GLNGIEIFSSKGEPVQISNIKADPPDINILPAYGKDPRVVTNLIDGVNRTQDDMHVWLAPFTRGRSHSITIDFTHPCHVALIRIWNYNKS RIHSFRGVKDITMLLDTQCIFEGEIAKASGTLAGAPEHFGDTILFTTDDDILEAIFYSDEMFDLDVGSLDSLQDEEAMRRPSTADGEGDE RPFTQAGLGADERIPELELPSSSPVPQVTTPEPGIYHGICLQLNFTASWGDLHYLGLTGLEVVGKEGQALPIHLHQISASPRDLNELPEY SDDSRALDKLIDGTNITMEDEHMWLIPFSPGLDHVVTIRLDRAESIAGLRFWNYNKSPEDTYRGAKIVHVSLDGLCVSPPEGFLIRKGPG NCHFDFAQEILFVDYLRAQLLPQPARRLDMRSLECASMDYEAPLMPCGFIFQFQLLTSWGDPYYIGLTGLELYDERGEKIPLSENNIAAF PDSVNSLEGVGGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMIKLWNYAKTPHRGVKEFGLLVDDLLVYNGILA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NFATC2IP_ENST00000320805_chr16_28963525_+_KIAA0556_ENST00000261588_chr16_27760905_+_2694nt ATGGCGGAGCCTGTGGGGAAGCGGGGCCGCTGGTCCGGAGGTAGCGGTGCCGGCCGAGGGGGTCGGGGCGGCTGGGGCGGTCGGGGCCGG CGTCCTCGGGCCCAGCGGTCTCCATCCCGGGGCACGCTGGACGTAGTGTCTGTGGACTTGGTCACCGACAGCGATGAGGAAATTCTGGAG GTCGCCACCGCTCGCGGTGCCGCGGACGAGGTTGAGGTGGAGCCCCCGGAGCCCCCGGGGCCGGTCGCGTCCCGGGATAACAGCAACAGT GACAGCGAAGGGGAGGACAGGCGGCCCGCAGGACCCCCGCGGGAGCCGGTCAGGCGGCGGCGGCGGCTGGTGCTGGATCCGGGGGAGGCG CCGCTGGTTCCGGTGTACTCGGGGAAGGTTAAAAGCAGCCTTCGCCTTATCCCAGATGATCTATCCCTCCTGAAACTCTACCCTCCAGGG GATGAGGAAGAAGACACCTGGTCTTCCAGGACGCCGTCACGGTCAAGGTGGCGCAGTGAGCAGGAGCACACACTTCACGAGTCATGGAGC TCCCTCAGTGCCTTCGACCGCTCCCACCGGGGACGCATCTCCAACACGGAGCTCCCGGGGGACATCCTGGATGAGCTCCTGCAGCAAAAG AGCAGCCGGCACAGCGACTTGCCCCCCTCCAAGAAGGGGGAGCAGCCAGGGCTGTCGAGAGGGCAGGATGGCTACTCTGGAGAGACAGAC GCTGGGGGTGACTTTAAAATCCCCGTCTTGCCTTATGGACAGCGCTTGGTCATTGACATCAAGTCTACCTGGGGGGACAGACACTATGTC GGCCTCAACGGAATAGAAATATTCAGTTCCAAGGGTGAACCGGTGCAGATTTCAAACATAAAAGCAGACCCTCCCGATATCAATATTTTA CCAGCCTATGGGAAAGACCCCCGCGTGGTCACCAACCTCATCGACGGGGTGAACAGGACCCAGGATGACATGCATGTCTGGCTGGCCCCC TTCACGCGGGGCAGATCCCACTCCATCACCATTGACTTCACGCACCCTTGCCACGTTGCCCTGATCAGAATTTGGAACTACAATAAATCT CGGATACATTCCTTCCGAGGCGTGAAGGACATCACAATGCTGTTAGACACCCAGTGCATCTTTGAAGGAGAAATCGCCAAGGCCTCTGGA ACCCTGGCGGGAGCCCCAGAGCACTTTGGAGACACGATCTTATTCACAACCGATGATGACATTCTCGAGGCCATATTCTATTCTGATGAG ATGTTTGACCTGGATGTGGGGAGCCTGGACAGCCTGCAGGATGAAGAGGCAATGAGGAGGCCCAGCACGGCCGACGGCGAGGGGGATGAG CGGCCCTTCACCCAGGCTGGCTTGGGGGCTGATGAACGGATCCCGGAGCTAGAGCTCCCATCCAGTTCCCCTGTCCCCCAAGTCACCACG CCAGAGCCAGGCATCTACCACGGAATCTGCCTTCAGCTGAATTTCACTGCCTCCTGGGGAGACTTGCACTACCTGGGGCTCACTGGCCTG GAAGTGGTGGGCAAGGAGGGCCAGGCGCTGCCCATCCACCTGCACCAGATCTCTGCTTCCCCCAGAGACTTAAATGAGCTCCCCGAGTAC TCTGACGACTCCCGGGCCCTGGACAAGTTAATTGATGGCACCAACATCACCATGGAGGATGAGCATATGTGGCTGATCCCCTTCTCGCCG GGGCTGGACCATGTGGTCACGATCCGCCTGGACAGGGCCGAAAGCATCGCAGGCCTGCGCTTCTGGAACTACAATAAATCTCCCGAGGAC ACCTATCGCGGGGCCAAGATTGTCCACGTCTCCCTGGATGGCCTGTGCGTCTCCCCGCCAGAGGGCTTTCTCATCCGGAAGGGGCCAGGC AACTGCCACTTTGATTTTGCTCAAGAAATCCTCTTCGTGGACTACCTACGGGCTCAGCTGCTGCCCCAGCCGGCCAGGAGGCTGGACATG AGAAGCCTGGAGTGTGCAAGCATGGACTACGAGGCACCGCTGATGCCCTGTGGCTTCATTTTCCAGTTTCAGCTTCTCACCAGCTGGGGC GACCCCTACTACATCGGCCTCACCGGCCTGGAGCTGTATGACGAGCGAGGAGAAAAAATCCCCTTGTCGGAAAACAATATTGCGGCCTTC CCCGACAGCGTGAACTCCCTGGAGGGTGTGGGCGGGGACGTCCGCACCCCAGACAAGCTCATCGACCAAGTGAACGACACCAGTGATGGC CGGCACATGTGGCTGGCTCCCATCCTGCCGGGCCTGGTGAACCGGGTTTATGTGATTTTCGATCTGCCTACCACCGTGTCAATGATCAAA CTGTGGAATTATGCGAAAACACCCCATCGAGGGGTGAAGGAGTTTGGCCTCCTGGTGGACGACCTGCTTGTGTACAATGGGATCCTGGCC ATGGTGAGCCACCTGGTGGGGGGCATCCTGCCCACATGTGAGCCCACCGTGCCCTACCACACCATCCTCTTCACCGAGGACAGGGACATC CGCCACCAGGAGAAACACACCACCATCAGTAATCAGGCCGAGGATCAAGATGTCCAGATGATGAATGAAAACCAAATCATTACCAACGCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NFATC2IP_ENST00000320805_chr16_28963525_+_KIAA0556_ENST00000261588_chr16_27760905_+_4509nt TGCAAGGCGAAAGTCGCTGAAGGGGGCGGGGCGAGGCGAGAGGAGGCGGGCGTGTGTTGTGGAGGAAAGTGTGCCATGGCGGAGCCTGTG GGGAAGCGGGGCCGCTGGTCCGGAGGTAGCGGTGCCGGCCGAGGGGGTCGGGGCGGCTGGGGCGGTCGGGGCCGGCGTCCTCGGGCCCAG CGGTCTCCATCCCGGGGCACGCTGGACGTAGTGTCTGTGGACTTGGTCACCGACAGCGATGAGGAAATTCTGGAGGTCGCCACCGCTCGC GGTGCCGCGGACGAGGTTGAGGTGGAGCCCCCGGAGCCCCCGGGGCCGGTCGCGTCCCGGGATAACAGCAACAGTGACAGCGAAGGGGAG GACAGGCGGCCCGCAGGACCCCCGCGGGAGCCGGTCAGGCGGCGGCGGCGGCTGGTGCTGGATCCGGGGGAGGCGCCGCTGGTTCCGGTG TACTCGGGGAAGGTTAAAAGCAGCCTTCGCCTTATCCCAGATGATCTATCCCTCCTGAAACTCTACCCTCCAGGGGATGAGGAAGAAGAC ACCTGGTCTTCCAGGACGCCGTCACGGTCAAGGTGGCGCAGTGAGCAGGAGCACACACTTCACGAGTCATGGAGCTCCCTCAGTGCCTTC GACCGCTCCCACCGGGGACGCATCTCCAACACGGAGCTCCCGGGGGACATCCTGGATGAGCTCCTGCAGCAAAAGAGCAGCCGGCACAGC GACTTGCCCCCCTCCAAGAAGGGGGAGCAGCCAGGGCTGTCGAGAGGGCAGGATGGCTACTCTGGAGAGACAGACGCTGGGGGTGACTTT AAAATCCCCGTCTTGCCTTATGGACAGCGCTTGGTCATTGACATCAAGTCTACCTGGGGGGACAGACACTATGTCGGCCTCAACGGAATA GAAATATTCAGTTCCAAGGGTGAACCGGTGCAGATTTCAAACATAAAAGCAGACCCTCCCGATATCAATATTTTACCAGCCTATGGGAAA GACCCCCGCGTGGTCACCAACCTCATCGACGGGGTGAACAGGACCCAGGATGACATGCATGTCTGGCTGGCCCCCTTCACGCGGGGCAGA TCCCACTCCATCACCATTGACTTCACGCACCCTTGCCACGTTGCCCTGATCAGAATTTGGAACTACAATAAATCTCGGATACATTCCTTC CGAGGCGTGAAGGACATCACAATGCTGTTAGACACCCAGTGCATCTTTGAAGGAGAAATCGCCAAGGCCTCTGGAACCCTGGCGGGAGCC CCAGAGCACTTTGGAGACACGATCTTATTCACAACCGATGATGACATTCTCGAGGCCATATTCTATTCTGATGAGATGTTTGACCTGGAT GTGGGGAGCCTGGACAGCCTGCAGGATGAAGAGGCAATGAGGAGGCCCAGCACGGCCGACGGCGAGGGGGATGAGCGGCCCTTCACCCAG GCTGGCTTGGGGGCTGATGAACGGATCCCGGAGCTAGAGCTCCCATCCAGTTCCCCTGTCCCCCAAGTCACCACGCCAGAGCCAGGCATC TACCACGGAATCTGCCTTCAGCTGAATTTCACTGCCTCCTGGGGAGACTTGCACTACCTGGGGCTCACTGGCCTGGAAGTGGTGGGCAAG GAGGGCCAGGCGCTGCCCATCCACCTGCACCAGATCTCTGCTTCCCCCAGAGACTTAAATGAGCTCCCCGAGTACTCTGACGACTCCCGG GCCCTGGACAAGTTAATTGATGGCACCAACATCACCATGGAGGATGAGCATATGTGGCTGATCCCCTTCTCGCCGGGGCTGGACCATGTG GTCACGATCCGCCTGGACAGGGCCGAAAGCATCGCAGGCCTGCGCTTCTGGAACTACAATAAATCTCCCGAGGACACCTATCGCGGGGCC AAGATTGTCCACGTCTCCCTGGATGGCCTGTGCGTCTCCCCGCCAGAGGGCTTTCTCATCCGGAAGGGGCCAGGCAACTGCCACTTTGAT TTTGCTCAAGAAATCCTCTTCGTGGACTACCTACGGGCTCAGCTGCTGCCCCAGCCGGCCAGGAGGCTGGACATGAGAAGCCTGGAGTGT GCAAGCATGGACTACGAGGCACCGCTGATGCCCTGTGGCTTCATTTTCCAGTTTCAGCTTCTCACCAGCTGGGGCGACCCCTACTACATC GGCCTCACCGGCCTGGAGCTGTATGACGAGCGAGGAGAAAAAATCCCCTTGTCGGAAAACAATATTGCGGCCTTCCCCGACAGCGTGAAC TCCCTGGAGGGTGTGGGCGGGGACGTCCGCACCCCAGACAAGCTCATCGACCAAGTGAACGACACCAGTGATGGCCGGCACATGTGGCTG GCTCCCATCCTGCCGGGCCTGGTGAACCGGGTTTATGTGATTTTCGATCTGCCTACCACCGTGTCAATGATCAAACTGTGGAATTATGCG AAAACACCCCATCGAGGGGTGAAGGAGTTTGGCCTCCTGGTGGACGACCTGCTTGTGTACAATGGGATCCTGGCCATGGTGAGCCACCTG GTGGGGGGCATCCTGCCCACATGTGAGCCCACCGTGCCCTACCACACCATCCTCTTCACCGAGGACAGGGACATCCGCCACCAGGAGAAA CACACCACCATCAGTAATCAGGCCGAGGATCAAGATGTCCAGATGATGAATGAAAACCAAATCATTACCAACGCGAAACGGAAGCAGAGC GTTGTTGACCCAGCCTTACGTCCCAAAACCTGCATCAGCGAGAAGGAGACGAGACGACGGCGCTGCTGACTGGTGAAGGAGGGAGAGCTG GTCCTCCCACTATGGTGGGCTCCGTCAGCAGCCCCACTCAGTGCCTGCGTCCCTCACCCTCAGTCCCAGGAGCTGGAAGCGAACCACAGT GTTGAGGGGAGCCCGCTGGGAAGAGGGGACTCGGGAGGACAGCCCTGGATACTACCAGAGTGACAGATGGCTGTGGCTGCAGGGCAAAGA GATCCCCTGCAGTTCTGGGTTGGCCACAGGGAGCCCAGGACACCCGCCTTCATGCCTCTGCTGTGAGACCCAGCAAAGCAGGGCCCATGA CCACTAGGGCCTGGGCTGACCCTGACTCAGAACAGGACAATGACGGGGTGGGGAGGCATCCCATCCAGCCTCAGAGGGCCCAGAGAATGG CTGAGCAGGACAGTGGGAGACCAGACCCTACCCCGCAACTCCAGTAAGCAGGGCACTGCCCAGGGAGACTGCCTTCAGAAACCTGAGCTT CAGCGGCCAACACCCCCCATCCCCTGCGCATCCTTGTCTCATTTGGGGACTGGTGGAGCTGGCTGAGAGGTTGGGGTAGTTTCCTGGTTA CAGGGGTCCACAAGACCCTCTCTCATCCCGGTATAGGGGCCTCTCTCCTCTCATCGGGCCTGATAAGGGATTGGCCAAGGCTGTGTGCAT CCTGCAGAGGGAAGGAAGTCAGCTGGGCCACCCGCCATCCACCTTGGCAAGAGCTGGGCCCACTCTGGCAGGCCAGGGTATCATCTGCGT GCTGCTGCCGGGCCAGGAAGGGTGGGTGGGTGGCCAGCAGGCTGGCAGCTCCAGACCCCAGAGGGCCAGAAGAACTCACCCCAGTGCCCT CTGGATGCAGGTGTTGGGGAACACTGAGGACAATCCCCCATCTCCCCTCACCCTTGAGCAGGCCCTCCCTGCACTCTCTGCCACATGTCC CTCCTGGTCTGATCACGGCTGTGCTCACTGATGTGGCTGCTTTCTGTCTCTGCCCCTGTGCCCTTGGAGGCAGGCAGTGAGGTGCTCCTT TCCCAGGCCCCCACCCCTTCTCCCCCTTCAGCCACTTCCCAGCGAGTTGGAAATGTGCCTTGCACCCCCAGCCGAGTGAAGCCCAGAACG CATCTATATGCATCGATGTAACAAGCTCGGATCAGGGACCTAATTGGTTTCCCAGTAGTGGGTAATTTCTCGTTGCAAATATTAATCCGT TGTTTTTCTGGCGCCCAGCCCGGCCCGCCGCAGTACTGTACTCGAGGTACGTTCCTATGCAACCGAGAGCCCCGGCAAATACTTCATGAG CTTAGCAGCCTGGGCTCGAGCAGCTATGCAAACGCGCTTTTCATTTGGAGCACGGGGCTGATGTGAAGATAAGAATTGTTTCTCCTGGAG AAAGATCCATCATTTCTCCAGCTTCCAAGCCCCCGGCACCTCTGCTCAGCTCCCAGATGTGACGAGCACCTCCCGCCAGGGGGAGTCAGG GGTTGATCAAACCAGCTCTTGTGACCCAAACCAGTGCCGCTGCATTAAAGGGAGGCCCAGCTACTCCTTCCCAGCTGAGATGTGGGTACA GGTCAGATTTGTCAGGGAGATGGCACTAACACGACACAAGCTCACTCCCAGAACCGCAGCTGATGTTTATAATAATCGTATGTACTGTGC AATTTAGGAGGGGAAAAAAAGGCTGTACAAGCTTTAACTCTAAAATAAATTTCTATTTTTTTCCTCTTGCAAAATTAATAAAAGATGTTA |
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FusionGenePPI for NFATC2IP_KIAA0556 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NFATC2IP | BATF3, TRAF1, TRAF2, TRAF3, TRAF5, TRAF6, MOV10, NXF1, ZDHHC17, GTF2I, RNMT, SMNDC1, TCEA1, TMA7, ZMAT2, HIST1H2BG, FOS, WDYHV1, P4HA3, CHD8, ACTR6, ELF2, ZNHIT1, PDLIM5, SRCAP, VPS72, RHEB, DMAP1, PDLIM7, EIF4G3, EIF4G1, SMARCA1 | KIAA0556 | XPO1, KIF2A, LLGL2, MAK, ICK |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NFATC2IP_KIAA0556 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NFATC2IP_KIAA0556 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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