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Fusion gene ID: 23504 |
FusionGeneSummary for NBEA_NDFIP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NBEA_NDFIP2 | Fusion gene ID: 23504 | Hgene | Tgene | Gene symbol | NBEA | NDFIP2 | Gene ID | 26960 | 54602 |
| Gene name | neurobeachin | Nedd4 family interacting protein 2 | |
| Synonyms | BCL8B|LYST2 | N4WBP5A | |
| Cytomap | 13q13.3 | 13q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neurobeachinlysosomal-trafficking regulator 2 | NEDD4 family-interacting protein 2MAPK-activating protein PM04 PM05 PM06 PM07NEDD4 WW domain-binding protein 5ANF-kappa-B-activating protein 413putative MAPK-activating protein PM04/PM05/PM06/PM07putative NF-kappa-B-activating protein 413 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q8NFP9 | Q9NV92 | |
| Ensembl transtripts involved in fusion gene | ENST00000540320, ENST00000400445, ENST00000310336, ENST00000379939, ENST00000537702, ENST00000379922, ENST00000461581, | ENST00000218652, ENST00000494647, | |
| Fusion gene scores | * DoF score | 7 X 7 X 6=294 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NBEA [Title/Abstract] AND NDFIP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-50-6591-01A | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000540320 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| 5CDS-3UTR | ENST00000540320 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| In-frame | ENST00000400445 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| 5CDS-3UTR | ENST00000400445 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| In-frame | ENST00000310336 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| 5CDS-3UTR | ENST00000310336 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| In-frame | ENST00000379939 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| 5CDS-3UTR | ENST00000379939 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3CDS | ENST00000537702 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3UTR | ENST00000537702 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3CDS | ENST00000379922 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3UTR | ENST00000379922 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3CDS | ENST00000461581 | ENST00000218652 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
| intron-3UTR | ENST00000461581 | ENST00000494647 | NBEA | chr13 | 35517251 | + | NDFIP2 | chr13 | 80094945 | + |
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FusionProtFeatures for NBEA_NDFIP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NBEA | NDFIP2 |
| Binds to type II regulatory subunits of protein kinase Aand anchors/targets them to the membrane. May anchor the kinase tocytoskeletal and/or organelle-associated proteins (By similarity).{ECO:0000250}. | Activates HECT domain-containing E3 ubiquitin-proteinligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, andconsequently modulates the stability of their targets. As aresult, may control many cellular processes. Recruits ITCH, NEDD4and SMURF2 to endosomal membranes. Negatively regulates KCNH2potassium channel activity by decreasing its cell-surfaceexpression and interfering with channel maturation throughrecruitment of NEDD4L to the Golgi apparatus and multivesicularbody where it mediates KCNH2 degradation (PubMed:26363003). Maymodulate EGFR signaling. Together with NDFIP1, limits the cytokinesignaling and expansion of effector Th2 T-cells by promotingdegradation of JAK1, probably by ITCH- and NEDD4L-mediatedubiquitination (By similarity). {ECO:0000250|UniProtKB:Q91ZP6,ECO:0000269|PubMed:12761501, ECO:0000269|PubMed:19343052,ECO:0000269|PubMed:20534535, ECO:0000269|PubMed:26363003}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 148_151 | 107 | 1399 | Motif | Note=PPxY motif 1 |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 174_177 | 107 | 1399 | Motif | Note=PPxY motif 2 |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 184_186 | 107 | 1399 | Motif | Note=PPxY motif 3 |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 253_257 | 107 | 1399 | Topological domain | Extracellular |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 279_287 | 107 | 1399 | Topological domain | Cytoplasmic |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 309_336 | 107 | 1399 | Topological domain | Extracellular |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 232_252 | 107 | 1399 | Transmembrane | Helical |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 258_278 | 107 | 1399 | Transmembrane | Helical |
| Tgene | >NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 288_308 | 107 | 1399 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2147_2255 | -159 | 525 | Domain | BEACH-type PH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2274_2563 | -159 | 525 | Domain | BEACH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2147_2255 | 98 | 2947 | Domain | BEACH-type PH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2274_2563 | 98 | 2947 | Domain | BEACH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2147_2255 | -42 | 740 | Domain | BEACH-type PH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2274_2563 | -42 | 740 | Domain | BEACH |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 1326_1368 | -159 | 525 | Repeat | WD 1 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2718_2761 | -159 | 525 | Repeat | WD 2 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2778_2818 | -159 | 525 | Repeat | WD 3 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2860_2899 | -159 | 525 | Repeat | WD 4 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000379922 | + | 1 | 13 | 2902_2941 | -159 | 525 | Repeat | WD 5 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 1326_1368 | 98 | 2947 | Repeat | WD 1 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2718_2761 | 98 | 2947 | Repeat | WD 2 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2778_2818 | 98 | 2947 | Repeat | WD 3 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2860_2899 | 98 | 2947 | Repeat | WD 4 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000400445 | + | 1 | 58 | 2902_2941 | 98 | 2947 | Repeat | WD 5 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 1326_1368 | -42 | 740 | Repeat | WD 1 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2718_2761 | -42 | 740 | Repeat | WD 2 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2778_2818 | -42 | 740 | Repeat | WD 3 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2860_2899 | -42 | 740 | Repeat | WD 4 |
| Hgene | >NBEA | chr13:35517251 | chr13:80094945 | ENST00000537702 | + | 1 | 18 | 2902_2941 | -42 | 740 | Repeat | WD 5 |
| Tgene | NDFIP2 | chr13:35517251 | chr13:80094945 | ENST00000218652 | + | 0 | 8 | 1_231 | 107 | 1399 | Topological domain | Cytoplasmic |
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FusionGeneSequence for NBEA_NDFIP2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NBEA_ENST00000540320_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_328aa MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSGSVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRD IVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEA EKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIV >In-frame_NBEA_ENST00000400445_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_328aa MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSGSVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRD IVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEA EKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIV >In-frame_NBEA_ENST00000310336_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_328aa MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSGSVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRD IVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEA EKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIV >In-frame_NBEA_ENST00000379939_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_328aa MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSGSVMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRD IVETVLNLLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEA EKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NBEA_ENST00000540320_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_984nt ATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGG GGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATG ATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGAC ATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCA CCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCT ACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCT GAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTC AGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGT TTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTC AGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGA >In-frame_NBEA_ENST00000400445_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_984nt ATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGG GGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATG ATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGAC ATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCA CCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCT ACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCT GAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTC AGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGT TTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTC AGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGA >In-frame_NBEA_ENST00000310336_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_984nt ATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGG GGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATG ATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGAC ATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCA CCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCT ACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCT GAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTC AGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGT TTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTC AGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGA >In-frame_NBEA_ENST00000379939_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_984nt ATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGG GGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATG ATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGAC ATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCA CCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCT ACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCT GAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTC AGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGT TTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTC AGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NBEA_ENST00000540320_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_5080nt AGGCAGGGGGCGGCAACATGGCGGAGTGAGCGGCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCGGCAGCAGCGTCA ATAGCATCGGCCACAGCCTGAGCTTCAGCACCGGCCAGCGTCGTGGCCAGCTGCTCGCGTCCTCGGGCTTCTCGGAGCGGCTGCAGCATC TCCGCGGGGGGCGGGCCGGGCCGGACAGACCGGGAGAGGGAGAGAGCAGAGGCAGCGGCGGCGGCAGCGGCAGCGGCAGCGGCACACCTG CTGGGCGGGCACAGCCGCTTGCCCGGCAGCGGTTAGCGGTACCGCCACCGCCGAGAATAAGCCTGCGGATCCCCCGCCGCCTCCGCGGGG GAGAGCGCCGGAGCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGG CCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCT AGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGC GGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAAC CCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTG GAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAG ATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACT TCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAG GCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGAT GCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCC TTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTT TCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTT GTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAA CCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAA ATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATAT TTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAG TCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCT GACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAA ACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTAT TATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAA TTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTA AAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACA TACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATT ATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAAT ATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTA TGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATA TAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCC ATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTAT CTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTAC ATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTG TCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTAT TGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTT AGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTC TTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCT ATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAG CATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAA TTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATC CTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAA AATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATT GTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCT ATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGA AAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCT AAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATT AAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAAT ATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATT TGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGA ACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAA TAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATT TATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCA TTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACC TGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAG ATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGT >In-frame_NBEA_ENST00000400445_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_5080nt AGGCAGGGGGCGGCAACATGGCGGAGTGAGCGGCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCGGCAGCAGCGTCA ATAGCATCGGCCACAGCCTGAGCTTCAGCACCGGCCAGCGTCGTGGCCAGCTGCTCGCGTCCTCGGGCTTCTCGGAGCGGCTGCAGCATC TCCGCGGGGGGCGGGCCGGGCCGGACAGACCGGGAGAGGGAGAGAGCAGAGGCAGCGGCGGCGGCAGCGGCAGCGGCAGCGGCACACCTG CTGGGCGGGCACAGCCGCTTGCCCGGCAGCGGTTAGCGGTACCGCCACCGCCGAGAATAAGCCTGCGGATCCCCCGCCGCCTCCGCGGGG GAGAGCGCCGGAGCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGG CCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCT AGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGC GGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAAC CCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTG GAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAG ATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACT TCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAG GCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGAT GCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCC TTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTT TCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTT GTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAA CCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAA ATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATAT TTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAG TCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCT GACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAA ACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTAT TATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAA TTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTA AAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACA TACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATT ATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAAT ATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTA TGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATA TAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCC ATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTAT CTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTAC ATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTG TCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTAT TGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTT AGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTC TTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCT ATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAG CATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAA TTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATC CTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAA AATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATT GTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCT ATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGA AAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCT AAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATT AAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAAT ATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATT TGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGA ACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAA TAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATT TATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCA TTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACC TGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAG ATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGT >In-frame_NBEA_ENST00000310336_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_4752nt GCGGCGTCGGGGCTTCACAACAACAGTGGTGGCCGTAGCAGCGGCCGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGG CGCTGGTGGATGCTGGGGCTCCGAGGCGACGGCCGGGGGGCGGGGGCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTC TTCCCTTCTCCTCAGGAGGGGGGCCAATGGCTAGCGAGAAGCCGGGCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCG TCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGCGGTGGTGGCGGCACCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCG GCTCGGTGATGCTCCCCGCGGGGATGATTAACCCTTCGGTGCCGATCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATAC AGGTCGGAGAGGTCAGCAACAGGGACATCGTGGAGACGGTGCTCAACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAG AGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCAT ATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTA CCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGG AAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCAT TTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTT CCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTG TACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAA GGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAAC TTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAA GCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGAT AGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCT TCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGC TCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATT TGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTT CTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACAC ACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTT TATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAG AGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCA TTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATA AAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCA TTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAAT TTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTT GAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTT ATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTAT AACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTC ATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTA AGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCA AACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACA TGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTT CTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTAT ACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAA GAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTG ATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAG TTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAA ACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACA TTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATG CCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATAT CCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATA GTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAG TGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAAC TACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTT GGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATAT TTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAA AGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTT AATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCT CACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTT >In-frame_NBEA_ENST00000379939_chr13_35517251_+_NDFIP2_ENST00000218652_chr13_80094945_+_4707nt CGGGCCGGGCTGAGGCGCAGGCGGGGAGCGGGCCCGGCGCCGCGGCGCTGGTGGATGCTGGGGCTCCGAGGCGACGGCCGGGGGGCGGGG GCCGAGGCAGGTATAACGGTACCGGCGGCGGCAGCGCCGCTGCTCTTCCCTTCTCCTCAGGAGGGGGGCCAATGGCTAGCGAGAAGCCGG GCCCGGGCCCGGGGCTCGAGCCTCAGCCCGTGGGGCTCATTGCCGTCGGGGCCGCTGGCGGAGGCGGCGGGGGCAGCGGTGGTGGCGGCA CCGGGGGCAGCGGGATGGGGGAGCTAAGGGGGGCGTCCGGCTCCGGCTCGGTGATGCTCCCCGCGGGGATGATTAACCCTTCGGTGCCGA TCCGCAACATCCGGATGAAATTCGCAGTGTTGATTGGACTCATACAGGTCGGAGAGGTCAGCAACAGGGACATCGTGGAGACGGTGCTCA ACCTGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTG CGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAG TTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTG CAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCA GAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCA ATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTA CTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAA AAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTT TCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAA AGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTG CACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTA ATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATA ATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTA TATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAAC TCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGT GAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTG TTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGG GATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCAT TTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATC ATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATT AACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGG TCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCA TTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAA AAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCA GGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATA AAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAA TTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCT AATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTA CTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGAC TTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCA CTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCC TTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCAT TTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTT GTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAG CTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGC AGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATC TTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTAT TTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTT TTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGT TTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTT ATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGG CAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGA ATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTA TTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAAT GTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCT TTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAA ACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGTGGTTTAATTTTAA |
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FusionGenePPI for NBEA_NDFIP2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NBEA | STRN4, DTNBP1, NOTCH1, VCP, FOSL2, RD3, TMEM17, PTPRH, ALOXE3, SHC4, RBM48, MRPL21, NAB2, STRADB | NDFIP2 | NEDD4, SLC11A2, PTEN, EGFR, LYN, FYN, SRC, ITCH, WWP2, NEDD4L, ELAVL1, TSPAN3, IL20RB, TMEM231, PTGFR, IL2RG, FAM8A1, SDHA, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NBEA_NDFIP2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NBEA_NDFIP2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | NBEA | C0004352 | Autistic Disorder | 2 | CTD_human |
| Hgene | NBEA | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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