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Fusion gene ID: 23343 |
FusionGeneSummary for NADK2_CDH1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NADK2_CDH1 | Fusion gene ID: 23343 | Hgene | Tgene | Gene symbol | NADK2 | CDH1 | Gene ID | 133686 | 51343 |
| Gene name | NAD kinase 2, mitochondrial | fizzy and cell division cycle 20 related 1 | |
| Synonyms | C5orf33|DECRD|MNADK|NADKD1 | CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1 | |
| Cytomap | 5p13.2 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | NAD kinase 2, mitochondrialNAD kinase domain-containing protein 1, mitochondrial | fizzy-related protein homologCDC20 homolog 1CDC20-like 1bCDC20-like protein 1cdh1/Hct1 homologfizzy/cell division cycle 20 related 1 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q4G0N4 | P12830 | |
| Ensembl transtripts involved in fusion gene | ENST00000397338, ENST00000282512, ENST00000381937, ENST00000511613, ENST00000506945, ENST00000514504, | ENST00000261769, ENST00000422392, ENST00000562836, | |
| Fusion gene scores | * DoF score | 6 X 7 X 3=126 | 9 X 10 X 3=270 |
| # samples | 7 | 12 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/270*10)=-1.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NADK2 [Title/Abstract] AND CDH1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | NADK2 | GO:0019674 | NAD metabolic process | 23212377 |
| Tgene | CDH1 | GO:0031145 | anaphase-promoting complex-dependent catabolic process | 18662541|21596315 |
| Tgene | CDH1 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint | 18662541 |
| Tgene | CDH1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity | 11459826 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A2-A4RW-01A | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000397338 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| Frame-shift | ENST00000397338 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5CDS-3UTR | ENST00000397338 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| In-frame | ENST00000282512 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| In-frame | ENST00000282512 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5CDS-3UTR | ENST00000282512 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| Frame-shift | ENST00000381937 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| Frame-shift | ENST00000381937 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5CDS-3UTR | ENST00000381937 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5UTR-3CDS | ENST00000511613 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5UTR-3CDS | ENST00000511613 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5UTR-3UTR | ENST00000511613 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| In-frame | ENST00000506945 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| In-frame | ENST00000506945 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| 5CDS-3UTR | ENST00000506945 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| intron-3CDS | ENST00000514504 | ENST00000261769 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| intron-3CDS | ENST00000514504 | ENST00000422392 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
| intron-3UTR | ENST00000514504 | ENST00000562836 | NADK2 | chr5 | 36207272 | - | CDH1 | chr16 | 68835573 | + |
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FusionProtFeatures for NADK2_CDH1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NADK2 | CDH1 |
| Mitochondrial NAD(+) kinase that phosphorylates NAD(+)to yield NADP(+). Can use both ATP or inorganic polyphosphate asthe phosphoryl donor. Also has weak NADH kinase activity in vitro;however NADH kinase activity is much weaker than the NAD(+) kinaseactivity and may not be relevant in vivo.{ECO:0000269|PubMed:23212377}. | Cadherins are calcium-dependent cell adhesion proteins(PubMed:11976333). They preferentially interact with themselves ina homophilic manner in connecting cells; cadherins may thuscontribute to the sorting of heterogeneous cell types. CDH1 isinvolved in mechanisms regulating cell-cell adhesions, mobilityand proliferation of epithelial cells (PubMed:11976333). Has apotent invasive suppressor role. It is a ligand for integrinalpha-E/beta-7. {ECO:0000269|PubMed:11976333,ECO:0000269|PubMed:16417575}. E-Cad/CTF2 promotes non-amyloidogenic degradation ofAbeta precursors. Has a strong inhibitory effect on APP C99 andC83 production. {ECO:0000269|PubMed:16417575}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for NADK2_CDH1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_984aa MLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALQKFYRGEFRWLWRQRIRLYLEGTGINPVPVDLHEQQLSLNQHNRALN IERAHDERSEASGPQLLPVRALNEVFIGESLSSRASYYEISVDDGPWEKQKSSGLNLCTGTGSKACEFXRLHRSTKDSLFFPRHPIQSGH RWCDYSQKASTVSXPTDPFLGLRLGLHLQKVFHQSHAEYSGAPPPPPAPSGLRFWNPSRIAHISQLLSWPQKTEERLGYSSHQLPRKXKR PISXKPGSDQIQQRQRRQGFLQHHWPRSXHTPCWCLYYXKRNRMAEGDRASGXRTHCHIHSLLSRCVIQRECSXGSNGDFDHGNRSEXQQ ARIHPGGLXGVCHGRCSSRNLCDGGHSHRRGRXCEHLQCRHRLHHPQPRSXAPXQKYVHHXQEHRSHQCGHHWAGPREFPYVYPGGSSCX PSRXGVKHNSNSCDHSHXHQRXSSDLQSHHVQGSGAXERGXRRNHHTESDXCXCPQYPSVGGCIHHIEXXWWTICRHHKSSEQRWHFENS KGLGFXGQAAVHSTRSSDECGTFXGLSHHLHSHRHRGCAGCEXSPHLCASXKESGSVRGLWRGPGNHILHCPGARHIYGTENNISDLERH CQLAGDXSGHWCHFHSGXAGQGGFXAREEQHVHSPNHSYRQWFSSCYWNRDTSADPVXCEXQRPHTRTSNYILLXEESKASGHKHHXCRP SSQYISLHSRTNTRGECQLDHSVQRPNPRIYHFEAKDGLRGGXLQNQSQAHGXPEXRPSDHLRGQRVXLXRGRWRLXEGTACRSRIANSC HSGDSWRNSCFANSDSAALAVSSEESGGQRALTAPRGXHPGQRLLLXXRRRRRRGPGLXLEPAAQGPGRSAXSDSXRRCTNPHECPPVSS >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_923aa MLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALQKFYRGEFRWLWRQRIRLYLEGTGINPVPVDLHEQQLSLNQHNRALN IERAHDERSEASGPQLLPVRALNEVFIGESLSSRASYYEISVDDGPWEKQKSSGLNLCTGTGSKACEFXRLHRSTKDSLFFPRHPIQSGH RWCDYSQKASTVSXPTDPFLGLRLGLHLQKVFHQSHAEYSGAPPPPPAPSGLRFWNPSRIAHISQLLSWPQKTEERLGYSSHQLPRKXKR PISXKPGSDQIQQRQRRQGFLQHHWPRSXHTPCWCLYYXKRNRMAEGDRASGXRTHCHIHSLLSRCVIQRECSXGSNGDFDHGNRSEXQQ ARIHPGGLXGVCHGRCSSRNLCDGGHSHRRGRXCEHLQCRHRLHHPQPRSXAPXQKYVHHXQEHRSHQCGHHWAGPREFPYVYPGGSSCX PSRXGVKHNSNSCDHSHXHQRXSSDLQSHHGLGFXGQAAVHSTRSSDECGTFXGLSHHLHSHRHRGCAGCEXSPHLCASXKESGSVRGLW RGPGNHILHCPGARHIYGTENNISDLERHCQLAGDXSGHWCHFHSGXAGQGGFXAREEQHVHSPNHSYRQWFSSCYWNRDTSADPVXCEX QRPHTRTSNYILLXEESKASGHKHHXCRPSSQYISLHSRTNTRGECQLDHSVQRPNPRIYHFEAKDGLRGGXLQNQSQAHGXPEXRPSDH LRGQRVXLXRGRWRLXEGTACRSRIANSCHSGDSWRNSCFANSDSAALAVSSEESGGQRALTAPRGXHPGQRLLLXXRRRRRRGPGLXLE PAAQGPGRSAXSDSXRRCTNPHECPPVSSPPCQSRXNWKFYXXKSESGXYXPHSPALXFSARVXLXRKRFRSCXSELPELLRVRQRPGLX >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_1006aa MLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALQKFYRGEFRWLWRQRIRLYLEGTGINPVPVDLHEQQLSLNQHNRALN IERAHDERSEASGPQLLPVRALNEVFIGESLSSRMSYSWAVAVDNLRRSIPTLKGLASYYEISVDDGPWEKQKSSGLNLCTGTGSKACEF XRLHRSTKDSLFFPRHPIQSGHRWCDYSQKASTVSXPTDPFLGLRLGLHLQKVFHQSHAEYSGAPPPPPAPSGLRFWNPSRIAHISQLLS WPQKTEERLGYSSHQLPRKXKRPISXKPGSDQIQQRQRRQGFLQHHWPRSXHTPCWCLYYXKRNRMAEGDRASGXRTHCHIHSLLSRCVI QRECSXGSNGDFDHGNRSEXQQARIHPGGLXGVCHGRCSSRNLCDGGHSHRRGRXCEHLQCRHRLHHPQPRSXAPXQKYVHHXQEHRSHQ CGHHWAGPREFPYVYPGGSSCXPSRXGVKHNSNSCDHSHXHQRXSSDLQSHHVQGSGAXERGXRRNHHTESDXCXCPQYPSVGGCIHHIE XXWWTICRHHKSSEQRWHFENSKGLGFXGQAAVHSTRSSDECGTFXGLSHHLHSHRHRGCAGCEXSPHLCASXKESGSVRGLWRGPGNHI LHCPGARHIYGTENNISDLERHCQLAGDXSGHWCHFHSGXAGQGGFXAREEQHVHSPNHSYRQWFSSCYWNRDTSADPVXCEXQRPHTRT SNYILLXEESKASGHKHHXCRPSSQYISLHSRTNTRGECQLDHSVQRPNPRIYHFEAKDGLRGGXLQNQSQAHGXPEXRPSDHLRGQRVX LXRGRWRLXEGTACRSRIANSCHSGDSWRNSCFANSDSAALAVSSEESGGQRALTAPRGXHPGQRLLLXXRRRRRRGPGLXLEPAAQGPG RSAXSDSXRRCTNPHECPPVSSPPCQSRXNWKFYXXKSESGXYXPHSPALXFSARVXLXRKRFRSCXSELPELLRVRQRPGLXLLERMGQ >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_945aa MLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALQKFYRGEFRWLWRQRIRLYLEGTGINPVPVDLHEQQLSLNQHNRALN IERAHDERSEASGPQLLPVRALNEVFIGESLSSRMSYSWAVAVDNLRRSIPTLKGLASYYEISVDDGPWEKQKSSGLNLCTGTGSKACEF XRLHRSTKDSLFFPRHPIQSGHRWCDYSQKASTVSXPTDPFLGLRLGLHLQKVFHQSHAEYSGAPPPPPAPSGLRFWNPSRIAHISQLLS WPQKTEERLGYSSHQLPRKXKRPISXKPGSDQIQQRQRRQGFLQHHWPRSXHTPCWCLYYXKRNRMAEGDRASGXRTHCHIHSLLSRCVI QRECSXGSNGDFDHGNRSEXQQARIHPGGLXGVCHGRCSSRNLCDGGHSHRRGRXCEHLQCRHRLHHPQPRSXAPXQKYVHHXQEHRSHQ CGHHWAGPREFPYVYPGGSSCXPSRXGVKHNSNSCDHSHXHQRXSSDLQSHHGLGFXGQAAVHSTRSSDECGTFXGLSHHLHSHRHRGCA GCEXSPHLCASXKESGSVRGLWRGPGNHILHCPGARHIYGTENNISDLERHCQLAGDXSGHWCHFHSGXAGQGGFXAREEQHVHSPNHSY RQWFSSCYWNRDTSADPVXCEXQRPHTRTSNYILLXEESKASGHKHHXCRPSSQYISLHSRTNTRGECQLDHSVQRPNPRIYHFEAKDGL RGGXLQNQSQAHGXPEXRPSDHLRGQRVXLXRGRWRLXEGTACRSRIANSCHSGDSWRNSCFANSDSAALAVSSEESGGQRALTAPRGXH PGQRLLLXXRRRRRRGPGLXLEPAAQGPGRSAXSDSXRRCTNPHECPPVSSPPCQSRXNWKFYXXKSESGXYXPHSPALXFSARVXLXRK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_2953nt ATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGC CTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGG TTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAAC ATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGT CTGTCATCCAGGGCTTCCTACTATGAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGA ACAGGATCAAAGGCCTGTGAATTTTGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCAC AGATGGTGTGATTACAGTCAAAAGGCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAA GTTTTCCACCAAAGTCACGCTGAATACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATT GCTCACATTTCCCAACTCCTCTCCTGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGG CCCATTTCCTAAAAACCTGGTTCAGATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACAC ACCCCCTGTTGGTGTCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACAC TCTCTTCTCTCACGCTGTGTCATCCAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAA GCCCGAATTCACCCAGGAGGTCTTTAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGC GGACGATGATGTGAACACCTACAATGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCAT TAACAGGAACACAGGAGTCATCAGTGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGA CCTTCAAGGTGAGGGGTTAAGCACAACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCAC GTACAAGGGTCAGGTGCCTGAGAACGAGGCTAACGTCGTAATCACCACACTGAAAGTGACTGATGCTGATGCCCCCAATACCCCAGCGTG GGAGGCTGTATACACCATATTGAATGATGATGGTGGACAATTTGTCGTCACCACAAATCCAGTGAACAACGATGGCATTTTGAAAACAGC AAAGGGCTTGGATTTTGAGGCCAAGCAGCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTC CACAGCCACCGTCACCGTGGATGTGCTGGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTT TGGCGTGGGCCAGGAAATCACATCCTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACAC TGCCAACTGGCTGGAGATTAATCCGGACACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAG CACGTACACAGCCCTAATCATAGCTACAGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAA TGACAACGCCCCCATACCAGAACCTCGAACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCT TCCTCCCAATACATCTCCCTTCACAGCAGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATC TATCATTTTGAAGCCAAAGATGGCCTTAGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGAC CACCTTAGAGGTCAGCGTGTGTGACTGTGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGC CATTCTGGGGATTCTTGGAGGAATTCTTGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGA GCCCTTACTGCCCCCAGAGGATGACACCCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTT GAGCCAGCTGCACAGGGGCCTGGACGCTCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCC CCGCCCTGCCAATCCCGATGAAATTGGAAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTC TCTGCTCGTGTTTGACTATGAAGGAAGCGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTA >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_2770nt ATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGC CTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGG TTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAAC ATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGT CTGTCATCCAGGGCTTCCTACTATGAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGA ACAGGATCAAAGGCCTGTGAATTTTGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCAC AGATGGTGTGATTACAGTCAAAAGGCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAA GTTTTCCACCAAAGTCACGCTGAATACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATT GCTCACATTTCCCAACTCCTCTCCTGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGG CCCATTTCCTAAAAACCTGGTTCAGATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACAC ACCCCCTGTTGGTGTCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACAC TCTCTTCTCTCACGCTGTGTCATCCAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAA GCCCGAATTCACCCAGGAGGTCTTTAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGC GGACGATGATGTGAACACCTACAATGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCAT TAACAGGAACACAGGAGTCATCAGTGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGA CCTTCAAGGTGAGGGGTTAAGCACAACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCAC GGGCTTGGATTTTGAGGCCAAGCAGCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCAC AGCCACCGTCACCGTGGATGTGCTGGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGG CGTGGGCCAGGAAATCACATCCTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGC CAACTGGCTGGAGATTAATCCGGACACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCAC GTACACAGCCCTAATCATAGCTACAGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGA CAACGCCCCCATACCAGAACCTCGAACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCC TCCCAATACATCTCCCTTCACAGCAGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTAT CATTTTGAAGCCAAAGATGGCCTTAGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCAC CTTAGAGGTCAGCGTGTGTGACTGTGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCAT TCTGGGGATTCTTGGAGGAATTCTTGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCC CTTACTGCCCCCAGAGGATGACACCCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAG CCAGCTGCACAGGGGCCTGGACGCTCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCG CCCTGCCAATCCCGATGAAATTGGAAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCT GCTCGTGTTTGACTATGAAGGAAGCGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGA >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_3019nt ATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGC CTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGG TTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAAC ATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGT CTGTCATCCAGAATGTCTTATTCTTGGGCTGTAGCAGTGGACAATTTAAGAAGAAGTATACCCACTCTAAAGGGACTGGCTTCCTACTAT GAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAAGGCCTGTGAATTT TGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGATTACAGTCAAAAG GCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCAAAGTCACGCTGAA TACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTCCCAACTCCTCTCC TGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTAAAAACCTGGTTCA GATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTGGTGTCTTTATTAT TGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTCACGCTGTGTCATC CAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCACCCAGGAGGTCTT TAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATGTGAACACCTACAA TGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACACAGGAGTCATCAG TGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTGAGGGGTTAAGCAC AACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGTACAAGGGTCAGGTGCCTGAGAA CGAGGCTAACGTCGTAATCACCACACTGAAAGTGACTGATGCTGATGCCCCCAATACCCCAGCGTGGGAGGCTGTATACACCATATTGAA TGATGATGGTGGACAATTTGTCGTCACCACAAATCCAGTGAACAACGATGGCATTTTGAAAACAGCAAAGGGCTTGGATTTTGAGGCCAA GCAGCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCGTCACCGTGGATGT GCTGGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGGAAATCACATC CTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGCTGGAGATTAATCC GGACACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCCTAATCATAGC TACAGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCCCCATACCAGAACC TCGAACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATACATCTCCCTTCAC AGCAGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGAAGCCAAAGATGGC CTTAGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGGTCAGCGTGTGTGA CTGTGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGATTCTTGGAGGAAT TCTTGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGCCCCCAGAGGATGA CACCCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGCACAGGGGCCTGGA CGCTCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCAATCCCGATGAAAT TGGAAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGTTTGACTATGAAGG AAGCGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGAACGAATGGGGCAA >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_2836nt ATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGC CTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGG TTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAAC ATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGT CTGTCATCCAGAATGTCTTATTCTTGGGCTGTAGCAGTGGACAATTTAAGAAGAAGTATACCCACTCTAAAGGGACTGGCTTCCTACTAT GAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAAGGCCTGTGAATTT TGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGATTACAGTCAAAAG GCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCAAAGTCACGCTGAA TACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTCCCAACTCCTCTCC TGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTAAAAACCTGGTTCA GATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTGGTGTCTTTATTAT TGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTCACGCTGTGTCATC CAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCACCCAGGAGGTCTT TAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATGTGAACACCTACAA TGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACACAGGAGTCATCAG TGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTGAGGGGTTAAGCAC AACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGGGCTTGGATTTTGAGGCCAAGCA GCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCGTCACCGTGGATGTGCT GGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGGAAATCACATCCTA CACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGCTGGAGATTAATCCGGA CACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCCTAATCATAGCTAC AGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCCCCATACCAGAACCTCG AACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATACATCTCCCTTCACAGC AGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGAAGCCAAAGATGGCCTT AGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGGTCAGCGTGTGTGACTG TGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGATTCTTGGAGGAATTCT TGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGCCCCCAGAGGATGACAC CCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGCACAGGGGCCTGGACGC TCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCAATCCCGATGAAATTGG AAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGTTTGACTATGAAGGAAG CGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGAACGAATGGGGCAATCG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_5238nt GGTGCGGGGAGGTCGCCCCCGGGCGGCGAAGCAGCCATTATGCAGGCCTTGCATTGAAAGGCTCTAGTTACAGTGGACTTCTTGAACGAC ATCATATTCACACCAAAAATGTAGAACATATTATAGATAGTTTACGGAATGAGGGAATTGAGGTTCGTCTAGTAAAGAGGAGAGAATATG ATGAAGAGACTGTTCGATGGGCAGATGCTGTCATAGCTGCAGGAGGTGATGGCACAATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGAC TTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGCCTGCCCGTTCGATATACACATTCCTTTCCAGAAG CCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGGTTATACCTTGAAGGGACTGGCATAAACCCTGTAC CTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAACATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTT CAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGTCTGTCATCCAGGGCTTCCTACTATGAGATTTCAG TTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAAGGCCTGTGAATTTTGAAGATTGC ACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGATTACAGTCAAAAGGCCTCTACGG TTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCAAAGTCACGCTGAATACAGTGGGG CACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTCCCAACTCCTCTCCTGGCCTCAGA AGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTAAAAACCTGGTTCAGATCAAATCC AACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTGGTGTCTTTATTATTGAAAGAGAA ACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTCACGCTGTGTCATCCAACGGGAAT GCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCACCCAGGAGGTCTTTAAGGGGTCT GTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATGTGAACACCTACAATGCCGCCATC GCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACACAGGAGTCATCAGTGTGGTCACC ACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTGAGGGGTTAAGCACAACAGCAACA GCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGTACAAGGGTCAGGTGCCTGAGAACGAGGCTAAC GTCGTAATCACCACACTGAAAGTGACTGATGCTGATGCCCCCAATACCCCAGCGTGGGAGGCTGTATACACCATATTGAATGATGATGGT GGACAATTTGTCGTCACCACAAATCCAGTGAACAACGATGGCATTTTGAAAACAGCAAAGGGCTTGGATTTTGAGGCCAAGCAGCAGTAC ATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCGTCACCGTGGATGTGCTGGATGTG AATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGGAAATCACATCCTACACTGCC CAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGCTGGAGATTAATCCGGACACTGGT GCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCCTAATCATAGCTACAGACAAT GGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCCCCATACCAGAACCTCGAACTATA TTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATACATCTCCCTTCACAGCAGAACTA ACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGAAGCCAAAGATGGCCTTAGAGGTG GGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGGTCAGCGTGTGTGACTGTGAAGGG GCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGATTCTTGGAGGAATTCTTGCTTTG CTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGCCCCCAGAGGATGACACCCGGGAC AACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGCACAGGGGCCTGGACGCTCGGCCT GAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCAATCCCGATGAAATTGGAAATTTT ATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGTTTGACTATGAAGGAAGCGGTTCC GAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGAACGAATGGGGCAATCGCTTCAAG AAGCTGGCTGACATGTACGGAGGCGGCGAGGACGACTAGGGGACTCGAGAGAGGCGGGCCCCAGACCCATGTGCTGGGAAATGCAGAAAT CACGTTGCTGGTGGTTTTTCAGCTCCCTTCCCTTGAGATGAGTTTCTGGGGAAAAAAAAGAGACTGGTTAGTGATGCAGTTAGTATAGCT TTATACTCTCTCCACTTTATAGCTCTAATAAGTTTGTGTTAGAAAAGTTTCGACTTATTTCTTAAAGCTTTTTTTTTTTTCCCATCACTC TTTACATGGTGGTGATGTCCAAAAGATACCCAAATTTTAATATTCCAGAAGAACAACTTTAGCATCAGAAGGTTCACCCAGCACCTTGCA GATTTTCTTAAGGAATTTTGTCTCACTTTTAAAAAGAAGGGGAGAAGTCAGCTACTCTAGTTCTGTTGTTTTGTGTATATAATTTTTTAA AAAAAATTTGTGTGCTTCTGCTCATTACTACACTGGTGTGTCCCTCTGCCTTTTTTTTTTTTTTAAGACAGGGTCTCATTCTATCGGCCA GGCTGGAGTGCAGTGGTGCAATCACAGCTCACTGCAGCCTTGTCCTCCCAGGCTCAAGCTATCCTTGCACCTCAGCCTCCCAAGTAGCTG GGACCACAGGCATGCACCACTACGCATGACTAATTTTTTAAATATTTGAGACGGGGTCTCCCTGTGTTACCCAGGCTGGTCTCAAACTCC TGGGCTCAAGTGATCCTCCCATCTTGGCCTCCCAGAGTATTGGGATTACAGACATGAGCCACTGCACCTGCCCAGCTCCCCAACTCCCTG CCATTTTTTAAGAGACAGTTTCGCTCCATCGCCCAGGCCTGGGATGCAGTGATGTGATCATAGCTCACTGTAACCTCAAACTCTGGGGCT CAAGCAGTTCTCCCACCAGCCTCCTTTTTATTTTTTTGTACAGATGGGGTCTTGCTATGTTGCCCAAGCTGGTCTTAAACTCCTGGCCTC AAGCAATCCTTCTGCCTTGGCCCCCCAAAGTGCTGGGATTGTGGGCATGAGCTGCTGTGCCCAGCCTCCATGTTTTAATATCAACTCTCA CTCCTGAATTCAGTTGCTTTGCCCAAGATAGGAGTTCTCTGATGCAGAAATTATTGGGCTCTTTTAGGGTAAGAAGTTTGTGTCTTTGTC TGGCCACATCTTGACTAGGTATTGTCTACTCTGAAGACCTTTAATGGCTTCCCTCTTTCATCTCCTGAGTATGTAACTTGCAATGGGCAG CTATCCAGTGACTTGTTCTGAGTAAGTGTGTTCATTAATGTTTATTTAGCTCTGAAGCAAGAGTGATATACTCCAGGACTTAGAATAGTG CCTAAAGTGCTGCAGCCAAAGACAGAGCGGAACTATGAAAAGTGGGCTTGGAGATGGCAGGAGAGCTTGTCATTGAGCCTGGCAATTTAG CAAACTGATGCTGAGGATGATTGAGGTGGGTCTACCTCATCTCTGAAAATTCTGGAAGGAATGGAGGAGTCTCAACATGTGTTTCTGACA CAAGATCCGTGGTTTGTACTCAAAGCCCAGAATCCCCAAGTGCCTGCTTTTGATGATGTCTACAGAAAATGCTGGCTGAGCTGAACACAT TTGCCCAATTCCAGGTGTGCACAGAAAACCGAGAATATTCAAAATTCCAAATTTTTTTCTTAGGAGCAAGAAGAAAATGTGGCCCTAAAG GGGGTTAGTTGAGGGGTAGGGGGTAGTGAGGATCTTGATTTGGATCTCTTTTTATTTAAATGTGAATTTCAACTTTTGACAATCAAAGAA AAGACTTTTGTTGAAATAGCTTTACTGTTTCTCAAGTGTTTTGGAGAAAAAAATCAACCCTGCAATCACTTTTTGGAATTGTCTTGATTT TTCGGCAGTTCAAGCTATATCGAATATAGTTCTGTGTAGAGAATGTCACTGTAGTTTTGAGTGTATACATGTGTGGGTGCTGATAATTGT GTATTTTCTTTGGGGGTGGAAAAGGAAAACAATTCAAGCTGAGAAAAGTATTCTCAAAGATGCATTTTTATAAATTTTATTAAACAATTT >In-frame_NADK2_ENST00000282512_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_3043nt GGTGCGGGGAGGTCGCCCCCGGGCGGCGAAGCAGCCATTATGCAGGCCTTGCATTGAAAGGCTCTAGTTACAGTGGACTTCTTGAACGAC ATCATATTCACACCAAAAATGTAGAACATATTATAGATAGTTTACGGAATGAGGGAATTGAGGTTCGTCTAGTAAAGAGGAGAGAATATG ATGAAGAGACTGTTCGATGGGCAGATGCTGTCATAGCTGCAGGAGGTGATGGCACAATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGAC TTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGAGGGTCATTTATGCCTGCCCGTTCGATATACACATTCCTTTCCAGAAG CCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAGGCAGAGAATCAGGTTATACCTTGAAGGGACTGGCATAAACCCTGTAC CTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAATAGAGCCCTTAACATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTT CAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTTCATTGGGGAGAGTCTGTCATCCAGGGCTTCCTACTATGAGATTTCAG TTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAAGGCCTGTGAATTTTGAAGATTGC ACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGATTACAGTCAAAAGGCCTCTACGG TTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCAAAGTCACGCTGAATACAGTGGGG CACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTCCCAACTCCTCTCCTGGCCTCAGA AGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTAAAAACCTGGTTCAGATCAAATCC AACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTGGTGTCTTTATTATTGAAAGAGAA ACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTCACGCTGTGTCATCCAACGGGAAT GCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCACCCAGGAGGTCTTTAAGGGGTCT GTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATGTGAACACCTACAATGCCGCCATC GCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACACAGGAGTCATCAGTGTGGTCACC ACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTGAGGGGTTAAGCACAACAGCAACA GCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGGGCTTGGATTTTGAGGCCAAGCAGCAGTACATT CTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCGTCACCGTGGATGTGCTGGATGTGAAT GAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGGAAATCACATCCTACACTGCCCAG GAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGCTGGAGATTAATCCGGACACTGGTGCC ATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCCTAATCATAGCTACAGACAATGGT TCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCCCCATACCAGAACCTCGAACTATATTC TTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATACATCTCCCTTCACAGCAGAACTAACA CACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGAAGCCAAAGATGGCCTTAGAGGTGGGT GACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGGTCAGCGTGTGTGACTGTGAAGGGGCC GCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGATTCTTGGAGGAATTCTTGCTTTGCTA ATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGCCCCCAGAGGATGACACCCGGGACAAC GTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGCACAGGGGCCTGGACGCTCGGCCTGAA GTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCAATCCCGATGAAATTGGAAATTTTATT GATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGTTTGACTATGAAGGAAGCGGTTCCGAA GCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGAACGAATGGGGCAATCGCTTCAAGAAG >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000261769_chr16_68835573_+_5441nt ATCGCCTAACAGAATTCTACCTCTTTCTCAGGCCGCAGCCAATGGCGCGGCCCCTCGGATCCGGAGCCGCCGCGGGCTCTGATTGGCCGA TAGAGTTAGCCTGGGGGCGGGAGAAGAGCGACCTCGGGGAAGCGTGTGGTGCGGGGAGGTCGCCCCCGGGCGGCGAAGCAGCCATTATGC AGGCCTTGCATTGAAAGGCTCTAGTTACAGTGGACTTCTTGAACGACATCATATTCACACCAAAAATGTAGAACATATTATAGATAGTTT ACGGAATGAGGGAATTGAGGTTCGTCTAGTAAAGAGGAGAGAATATGATGAAGAGACTGTTCGATGGGCAGATGCTGTCATAGCTGCAGG AGGTGATGGCACAATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGA GGGTCATTTATGCCTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAG GCAGAGAATCAGGTTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAA TAGAGCCCTTAACATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTT CATTGGGGAGAGTCTGTCATCCAGAATGTCTTATTCTTGGGCTGTAGCAGTGGACAATTTAAGAAGAAGTATACCCACTCTAAAGGGACT GGCTTCCTACTATGAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAA GGCCTGTGAATTTTGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGA TTACAGTCAAAAGGCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCA AAGTCACGCTGAATACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTC CCAACTCCTCTCCTGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTA AAAACCTGGTTCAGATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTG GTGTCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTC ACGCTGTGTCATCCAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCA CCCAGGAGGTCTTTAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATG TGAACACCTACAATGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACA CAGGAGTCATCAGTGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTG AGGGGTTAAGCACAACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGTACAAGGGTC AGGTGCCTGAGAACGAGGCTAACGTCGTAATCACCACACTGAAAGTGACTGATGCTGATGCCCCCAATACCCCAGCGTGGGAGGCTGTAT ACACCATATTGAATGATGATGGTGGACAATTTGTCGTCACCACAAATCCAGTGAACAACGATGGCATTTTGAAAACAGCAAAGGGCTTGG ATTTTGAGGCCAAGCAGCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCG TCACCGTGGATGTGCTGGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCC AGGAAATCACATCCTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGC TGGAGATTAATCCGGACACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAG CCCTAATCATAGCTACAGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCC CCATACCAGAACCTCGAACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATA CATCTCCCTTCACAGCAGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGA AGCCAAAGATGGCCTTAGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGG TCAGCGTGTGTGACTGTGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGA TTCTTGGAGGAATTCTTGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGC CCCCAGAGGATGACACCCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGC ACAGGGGCCTGGACGCTCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCA ATCCCGATGAAATTGGAAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGT TTGACTATGAAGGAAGCGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGA ACGAATGGGGCAATCGCTTCAAGAAGCTGGCTGACATGTACGGAGGCGGCGAGGACGACTAGGGGACTCGAGAGAGGCGGGCCCCAGACC CATGTGCTGGGAAATGCAGAAATCACGTTGCTGGTGGTTTTTCAGCTCCCTTCCCTTGAGATGAGTTTCTGGGGAAAAAAAAGAGACTGG TTAGTGATGCAGTTAGTATAGCTTTATACTCTCTCCACTTTATAGCTCTAATAAGTTTGTGTTAGAAAAGTTTCGACTTATTTCTTAAAG CTTTTTTTTTTTTCCCATCACTCTTTACATGGTGGTGATGTCCAAAAGATACCCAAATTTTAATATTCCAGAAGAACAACTTTAGCATCA GAAGGTTCACCCAGCACCTTGCAGATTTTCTTAAGGAATTTTGTCTCACTTTTAAAAAGAAGGGGAGAAGTCAGCTACTCTAGTTCTGTT GTTTTGTGTATATAATTTTTTAAAAAAAATTTGTGTGCTTCTGCTCATTACTACACTGGTGTGTCCCTCTGCCTTTTTTTTTTTTTTAAG ACAGGGTCTCATTCTATCGGCCAGGCTGGAGTGCAGTGGTGCAATCACAGCTCACTGCAGCCTTGTCCTCCCAGGCTCAAGCTATCCTTG CACCTCAGCCTCCCAAGTAGCTGGGACCACAGGCATGCACCACTACGCATGACTAATTTTTTAAATATTTGAGACGGGGTCTCCCTGTGT TACCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCCTCCCATCTTGGCCTCCCAGAGTATTGGGATTACAGACATGAGCCACTGCAC CTGCCCAGCTCCCCAACTCCCTGCCATTTTTTAAGAGACAGTTTCGCTCCATCGCCCAGGCCTGGGATGCAGTGATGTGATCATAGCTCA CTGTAACCTCAAACTCTGGGGCTCAAGCAGTTCTCCCACCAGCCTCCTTTTTATTTTTTTGTACAGATGGGGTCTTGCTATGTTGCCCAA GCTGGTCTTAAACTCCTGGCCTCAAGCAATCCTTCTGCCTTGGCCCCCCAAAGTGCTGGGATTGTGGGCATGAGCTGCTGTGCCCAGCCT CCATGTTTTAATATCAACTCTCACTCCTGAATTCAGTTGCTTTGCCCAAGATAGGAGTTCTCTGATGCAGAAATTATTGGGCTCTTTTAG GGTAAGAAGTTTGTGTCTTTGTCTGGCCACATCTTGACTAGGTATTGTCTACTCTGAAGACCTTTAATGGCTTCCCTCTTTCATCTCCTG AGTATGTAACTTGCAATGGGCAGCTATCCAGTGACTTGTTCTGAGTAAGTGTGTTCATTAATGTTTATTTAGCTCTGAAGCAAGAGTGAT ATACTCCAGGACTTAGAATAGTGCCTAAAGTGCTGCAGCCAAAGACAGAGCGGAACTATGAAAAGTGGGCTTGGAGATGGCAGGAGAGCT TGTCATTGAGCCTGGCAATTTAGCAAACTGATGCTGAGGATGATTGAGGTGGGTCTACCTCATCTCTGAAAATTCTGGAAGGAATGGAGG AGTCTCAACATGTGTTTCTGACACAAGATCCGTGGTTTGTACTCAAAGCCCAGAATCCCCAAGTGCCTGCTTTTGATGATGTCTACAGAA AATGCTGGCTGAGCTGAACACATTTGCCCAATTCCAGGTGTGCACAGAAAACCGAGAATATTCAAAATTCCAAATTTTTTTCTTAGGAGC AAGAAGAAAATGTGGCCCTAAAGGGGGTTAGTTGAGGGGTAGGGGGTAGTGAGGATCTTGATTTGGATCTCTTTTTATTTAAATGTGAAT TTCAACTTTTGACAATCAAAGAAAAGACTTTTGTTGAAATAGCTTTACTGTTTCTCAAGTGTTTTGGAGAAAAAAATCAACCCTGCAATC ACTTTTTGGAATTGTCTTGATTTTTCGGCAGTTCAAGCTATATCGAATATAGTTCTGTGTAGAGAATGTCACTGTAGTTTTGAGTGTATA CATGTGTGGGTGCTGATAATTGTGTATTTTCTTTGGGGGTGGAAAAGGAAAACAATTCAAGCTGAGAAAAGTATTCTCAAAGATGCATTT >In-frame_NADK2_ENST00000506945_chr5_36207272_-_CDH1_ENST00000422392_chr16_68835573_+_3246nt ATCGCCTAACAGAATTCTACCTCTTTCTCAGGCCGCAGCCAATGGCGCGGCCCCTCGGATCCGGAGCCGCCGCGGGCTCTGATTGGCCGA TAGAGTTAGCCTGGGGGCGGGAGAAGAGCGACCTCGGGGAAGCGTGTGGTGCGGGGAGGTCGCCCCCGGGCGGCGAAGCAGCCATTATGC AGGCCTTGCATTGAAAGGCTCTAGTTACAGTGGACTTCTTGAACGACATCATATTCACACCAAAAATGTAGAACATATTATAGATAGTTT ACGGAATGAGGGAATTGAGGTTCGTCTAGTAAAGAGGAGAGAATATGATGAAGAGACTGTTCGATGGGCAGATGCTGTCATAGCTGCAGG AGGTGATGGCACAATGCTGCTGGCAGCGAGTAAAGTCTTGGACAGACTTAAACCAGTTATAGGGGTAAACACTGATCCAGAACGGTCTGA GGGTCATTTATGCCTGCCCGTTCGATATACACATTCCTTTCCAGAAGCCTTACAGAAGTTCTATCGTGGTGAGTTCAGGTGGTTGTGGAG GCAGAGAATCAGGTTATACCTTGAAGGGACTGGCATAAACCCTGTACCTGTGGACCTTCACGAGCAGCAGCTAAGCTTGAATCAGCACAA TAGAGCCCTTAACATTGAAAGAGCTCATGATGAAAGGTCTGAGGCTTCAGGACCCCAACTTCTGCCAGTGAGAGCACTAAATGAAGTCTT CATTGGGGAGAGTCTGTCATCCAGAATGTCTTATTCTTGGGCTGTAGCAGTGGACAATTTAAGAAGAAGTATACCCACTCTAAAGGGACT GGCTTCCTACTATGAGATTTCAGTTGATGATGGTCCATGGGAAAAACAGAAGAGTTCAGGGCTCAATTTGTGTACTGGAACAGGATCAAA GGCCTGTGAATTTTGAAGATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGACACCCGATTCAAAGTGGGCACAGATGGTGTGA TTACAGTCAAAAGGCCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCA AAGTCACGCTGAATACAGTGGGGCACCACCACCGCCCCCCGCCCCATCAGGCCTCCGTTTCTGGAATCCAAGCAGAATTGCTCACATTTC CCAACTCCTCTCCTGGCCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCAGCTGCCCAGAAAATGAAAAAGGCCCATTTCCTA AAAACCTGGTTCAGATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCTACAGCATCACTGGCCAAGGAGCTGACACACCCCCTGTTG GTGTCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACAGAGCCTCTGGATAGAGAACGCATTGCCACATACACTCTCTTCTCTC ACGCTGTGTCATCCAACGGGAATGCAGTTGAGGATCCAATGGAGATTTTGATCACGGTAACCGATCAGAATGACAACAAGCCCGAATTCA CCCAGGAGGTCTTTAAGGGGTCTGTCATGGAAGGTGCTCTTCCAGGAACCTCTGTGATGGAGGTCACAGCCACAGACGCGGACGATGATG TGAACACCTACAATGCCGCCATCGCTTACACCATCCTCAGCCAAGATCCTGAGCTCCCTGACAAAAATATGTTCACCATTAACAGGAACA CAGGAGTCATCAGTGTGGTCACCACTGGGCTGGACCGAGAGAGTTTCCCTACGTATACCCTGGTGGTTCAAGCTGCTGACCTTCAAGGTG AGGGGTTAAGCACAACAGCAACAGCTGTGATCACAGTCACTGACACCAACGATAATCCTCCGATCTTCAATCCCACCACGGGCTTGGATT TTGAGGCCAAGCAGCAGTACATTCTACACGTAGCAGTGACGAATGTGGTACCTTTTGAGGTCTCTCTCACCACCTCCACAGCCACCGTCA CCGTGGATGTGCTGGATGTGAATGAAGCCCCCATCTTTGTGCCTCCTGAAAAGAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGG AAATCACATCCTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAATAACATATCGGATTTGGAGAGACACTGCCAACTGGCTGG AGATTAATCCGGACACTGGTGCCATTTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCC TAATCATAGCTACAGACAATGGTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCTGATGTGAATGACAACGCCCCCA TACCAGAACCTCGAACTATATTCTTCTGTGAGAGGAATCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTCCTCCCAATACAT CTCCCTTCACAGCAGAACTAACACACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCAACCCAAGAATCTATCATTTTGAAGC CAAAGATGGCCTTAGAGGTGGGTGACTACAAAATCAATCTCAAGCTCATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGGTCA GCGTGTGTGACTGTGAAGGGGCCGCTGGCGTCTGTAGGAAGGCACAGCCTGTCGAAGCAGGATTGCAAATTCCTGCCATTCTGGGGATTC TTGGAGGAATTCTTGCTTTGCTAATTCTGATTCTGCTGCTCTTGCTGTTTCTTCGGAGGAGAGCGGTGGTCAAAGAGCCCTTACTGCCCC CAGAGGATGACACCCGGGACAACGTTTATTACTATGATGAAGAAGGAGGCGGAGAAGAGGACCAGGACTTTGACTTGAGCCAGCTGCACA GGGGCCTGGACGCTCGGCCTGAAGTGACTCGTAACGACGTTGCACCAACCCTCATGAGTGTCCCCCGGTATCTTCCCCGCCCTGCCAATC CCGATGAAATTGGAAATTTTATTGATGAAAATCTGAAAGCGGCTGATACTGACCCCACAGCCCCGCCTTATGATTCTCTGCTCGTGTTTG ACTATGAAGGAAGCGGTTCCGAAGCTGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGAACG AATGGGGCAATCGCTTCAAGAAGCTGGCTGACATGTACGGAGGCGGCGAGGACGACTAGGGGACTCGAGAGAGGCGGGCCCCAGACCCAT |
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FusionGenePPI for NADK2_CDH1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| NADK2 | ELAVL1, NPTX1, IRF2BPL, FERMT2, MPST, TMEM189, DYNLL1, PNP, STMN1, ERMAP, HTRA2, TIMM9, TMEM177, VPS29, DNAJB11, SUCLA2, LYRM5 | CDH1 | CTNND1, CBLL1, HDAC1, HDAC2, CTNNB1, MET, SRC, VCL, ITGAE, CTNNA1, JUP, CSE1L, ACTG1, ACTN1, GNA13, CDH1, CDH3, GNA12, AJAP1, CA9, FYN, FER, YES1, RAB8B, PKP4, EGFR, MYO7A, VEZT, MAGI1, ARPC2, PSEN1, EZR, IQGAP1, MDM2, ADAM9, CREBBP, EP300, USP9X, NKD2, CDC42, NDRG1, PPP1CA, SMAD7, RAD17, ACTN4, HSP90AA1, HSPD1, HSPA8, POLR2E, XRCC5, KRT1, KRT9, LMNA, ACADVL, IGHA1, TGM2, HSPA5, HSPA9, KRT18, KRT8, SET, ANP32B, C1QBP, NIPSNAP1, GBAS, CRYAB, CFTR, GMNN, AP2M1, PIP5K1C, UCHL3, PTEN, CDC27, RNF2, ECT2, KLF4, E2F1, SKP2, DDR1, DDR2, ILK, MYO6, CASP3, FGFR1, GSK3B, NFE2L2, KEAP1, BRCA1, ADCY9, ADD1, ADD3, AIM1, ALDOA, ANK3, ANXA1, ANXA2, ANXA4, ARHGAP1, ARHGAP5, ARHGDIB, ARVCF, ATIC, ATP2B1, ATP2B4, BCL2L2, BMPR2, DST, BSG, CALD1, CAPG, CAPS, CAPZA1, CAST, CAPZB, CBL, SCARB1, SEPT7, CLIC1, CNN2, CNN3, COL17A1, CRK, CRKL, CSNK1A1, CSNK1D, CTNNA2, CTSB, CXADR, DAG1, DBN1, DDX3X, DDX6, DLG1, DSC3, DSG2, DVL3, EEF1A1, EEF1D, EEF1G, EEF2, EIF2S3, EPHA2, EIF4B, EIF4G1, EIF4G2, EIF5, EIF5A, EMD, MARK2, CTTN, ENO1, EPB41, EPB41L1, EPS15, ERBB2, ERBB3, EVPL, FASN, FLNA, FLNB, FTH1, GAB1, GM2A, GOLGA2, GOLGA3, GOLGB1, SFN, GSPT1, HCFC1, HDLBP, HLA-C, HNRNPK, AGFG1, HSPA1A, HSP90AB1, DNAJB1, IDH1, IGBP1, IGF2R, IL6ST, INPPL1, EIF3E, IRAK1, ITGA6, ITGB1, IVL, KCNN4, KIF5B, KTN1, LAD1, LASP1, LBR, LDHA, ABLIM1, LLGL1, LMO7, LPP, MARCKS, MAP4, MARK3, CD99, MLLT4, MRE11A, MYO1B, MYH9, NCK1, SEPT2, NF2, NFKBIE, NHS, NOTCH1, NOTCH2, NOTCH3, PRDX1, PAK2, PCBP1, PCBP2, PCDH1, PCMT1, PFKP, PFN1, PI4KA, PKM, PKP2, PLCB3, PLEC, PLSCR1, PPL, PKN2, PSMB6, TWF1, PTPN1, PTPRJ, PVRL1, PVRL2, PXN, RAB1A, RAN, RANBP1, RANGAP1, RARS, RDX, RPL6, RPL7A, RPL15, RPL23A, RPL24, RPL29, RPL34, RPL36AL, RPL37, RPL36A, RPS2, RPS26, S100A11, S100P, SDCBP, SH3GL1, SHB, SLC1A5, SLC3A2, SLC9A1, SLC12A2, SNAP25, FSCN1, SNX1, SNX2, SPAG1, SPRR3, SPTAN1, SPTBN1, SPTBN2, SSFA2, STAT1, STAT2, STIM1, CDKL5, STX4, SVIL, ADAM17, TJP1, TLN1, TMPO, TP53BP2, TPD52, TPD52L2, TRIP6, TTK, TTN, UBC, UTRN, VASP, EIF4H, YWHAB, YWHAE, YWHAZ, TRIM25, ZNF185, SLC30A1, ZYX, LUZP1, DDX39B, NUP214, PICALM, HIST1H3A, TAGLN2, STK24, NCK2, PPFIBP1, RUVBL1, USO1, NUMB, SNAP23, SCEL, SYNJ1, SYNJ2, H1FX, MPZL1, RPL14, GPRC5A, SYT7, USP8, SLC16A3, PDLIM1, CCNB2, LRRFIP1, VAPB, VAPA, RAB11B, DLG5, NUMBL, PDLIM7, TRIP11, VAMP3, SNAP29, SLC9A3R2, SLC9A3R1, ARHGAP29, TJP2, SLC4A7, BAG3, H2AFY, PRDX6, N4BP1, CLINT1, BZW1, USP6NL, ARHGAP32, SLK, PHACTR2, ZFYVE16, CKAP5, IST1, RB1CC1, GOLGA5, USP15, CCS, ABI1, WASF2, TXNDC9, INADL, FLOT1, PLIN3, PAK4, TUBB4B, GNB2L1, YAP1, PGRMC2, SEC24B, BAIAP2, NOP56, NEBL, SORBS1, AHSA1, PAICS, PDLIM5, YKT6, CCT8, NUDC, GIPC1, SEPT9, FRS2, PPP1R13L, RAB10, EHD1, EBNA1BP2, GCN1L1, CDC42EP1, NUDT5, PKP3, AKAP2, PACSIN2, ATXN2L, LYPLA2, PARK7, STK38, PDAP1, EXOC3, TWF2, PUF60, COBLL1, AAK1, PLEKHA6, ABLIM3, EPN2, MAPRE1, SHANK2, LIMCH1, DAAM1, PDXDC1, SWAP70, ERC1, SIPA1L3, EPB41L3, GGA3, MPRIP, EFR3A, LPHN2, EHBP1, ESYT1, DOCK9, ARHGEF12, LARP1, PPP1R13B, SRGAP2, MACF1, SCRIB, CDC42EP4, CD2AP, ARFIP2, TRIM29, TMEM2, ZDHHC5, KANK2, TMEM87A, CHMP2B, NGDN, TBC1D10B, GORASP2, GIGYF2, RAI14, GAPVD1, SERBP1, TES, RSL1D1, ELP4, COPG2, SND1, SNX5, ARFIP1, ARHGEF16, BZW2, DBNL, STXBP6, TMOD3, OLA1, SH3KBP1, EHD4, MINK1, ASAP1, F11R, GLOD4, SH3GLB1, HN1, PPME1, SNX9, LIMA1, ISYNA1, CHMP5, LSR, WWOX, ANLN, XRN1, PLEKHA5, DHX29, EPB41L4B, CC2D1A, EPS8L1, FNBP1L, SSH3, EPN3, UACA, ARGLU1, TMEM51, STEAP3, ABCF3, LRRC59, LRRC16A, FERMT1, TBC1D22B, NLRP2, DENND4C, SCYL2, PARVA, C1orf106, PAG1, UBAP2, ZC3H15, UNC45A, ERBB2IP, NSFL1C, BAIAP2L1, UBFD1, KIAA1217, PARD3, ZC3HAV1, SH3GLB2, PAK6, CIAPIN1, PLSCR3, CAMK1D, RTN4, CORO1B, TTC7A, NHSL1, SCYL1, NDRG2, ESYT2, MKL2, KIDINS220, MAVS, CASKIN2, CGN, LRRC7, ARHGAP21, KIAA1462, SHROOM3, SH3RF1, ARHGAP23, KIAA1522, KIAA1524, KIAA1598, EPS15L1, PLEKHA1, PLEKHA2, ACBD3, EPS8L2, KLC2, FAM129B, RAPH1, PHACTR4, AHNAK, EFHD2, CLMN, PEAK1, POF1B, VCPIP1, PLEKHO2, SRCIN1, SLC38A1, PVRL4, DIAPH3, CDCA3, FAM110A, TBC1D10A, EIF2A, ELMOD3, ARFGAP2, LZTS2, FAM126A, C1orf198, MICALL1, KIAA1671, TNKS1BP1, TANC1, NAV2, CCDC120, PHLDB2, HN1L, SPECC1, ARHGAP18, SYAP1, GPRIN1, FMNL2, ELFN2, VASN, ZG16B, CANT1, USP43, CCDC43, CHMP4B, SIRPA, MPP7, PLEKHA7, SLC2A14, GCOM1, TMEM199, WIPF2, VSIG10L, PROM2, MB21D2, SH3D19, DAB2IP, MARVELD2, FAM84B, FAM91A1, SPRED1, FAM171B, PPP1R18, TUBB, FAM83B, EHBP1L1, LRRC57, MAGI3, PPP1R37, FAM126B, SH3PXD2B, FAM83H, CCDC85C, FMN1, PALM3, MACC1, SBSN, GOLGA8B, FAM110C, C6orf132, RELL1, OCLN, STX5, C1orf116, ARPIN, KDF1, C1orf35, TENM3, CCSER2, CTNNA3, PCDHGC3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for NADK2_CDH1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for NADK2_CDH1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CDH1 | C0038356 | Stomach Neoplasms | 6 | CTD_human |
| Tgene | CDH1 | C1458155 | Mammary Neoplasms | 4 | CTD_human |
| Tgene | CDH1 | C0005695 | Bladder Neoplasm | 2 | CTD_human |
| Tgene | CDH1 | C0009404 | Colorectal Neoplasms | 2 | CTD_human |
| Tgene | CDH1 | C0023904 | Liver Neoplasms, Experimental | 2 | CTD_human |
| Tgene | CDH1 | C0027626 | Neoplasm Invasiveness | 2 | CTD_human |
| Tgene | CDH1 | C0027627 | Neoplasm Metastasis | 2 | CTD_human |
| Tgene | CDH1 | C0033578 | Prostatic Neoplasms | 2 | CTD_human |
| Tgene | CDH1 | C0206692 | Carcinoma, Lobular | 2 | CTD_human |
| Tgene | CDH1 | C1134719 | Invasive Ductal Breast Carcinoma | 2 | CTD_human |
| Tgene | CDH1 | C1708349 | Hereditary Diffuse Gastric Cancer | 2 | ORPHANET;UNIPROT |
| Tgene | CDH1 | C2931456 | Prostate cancer, familial | 2 | CTD_human |
| Tgene | CDH1 | C0007137 | Squamous cell carcinoma | 1 | CTD_human |
| Tgene | CDH1 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Tgene | CDH1 | C0009324 | Ulcerative Colitis | 1 | CTD_human |
| Tgene | CDH1 | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Tgene | CDH1 | C0014170 | Endometrial Neoplasms | 1 | CTD_human |
| Tgene | CDH1 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Tgene | CDH1 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| Tgene | CDH1 | C0025500 | Mesothelioma | 1 | CTD_human |
| Tgene | CDH1 | C0026936 | Mycoplasma Infections | 1 | CTD_human |
| Tgene | CDH1 | C0027746 | Nerve Degeneration | 1 | CTD_human |
| Tgene | CDH1 | C0030297 | Pancreatic Neoplasm | 1 | CTD_human |
| Tgene | CDH1 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Tgene | CDH1 | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| Tgene | CDH1 | C0079487 | Helicobacter Infections | 1 | CTD_human |
| Tgene | CDH1 | C0282612 | Prostatic Intraepithelial Neoplasias | 1 | CTD_human |
| Tgene | CDH1 | C0919267 | ovarian neoplasm | 1 | CTD_human |
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