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Fusion gene ID: 23257 |
FusionGeneSummary for N4BP2L1_ZBTB18 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: N4BP2L1_ZBTB18 | Fusion gene ID: 23257 | Hgene | Tgene | Gene symbol | N4BP2L1 | ZBTB18 | Gene ID | 90634 | 10472 |
| Gene name | NEDD4 binding protein 2 like 1 | zinc finger and BTB domain containing 18 | |
| Synonyms | CG018 | C2H2-171|MRD22|RP58|TAZ-1|ZNF238 | |
| Cytomap | 13q13.1 | 1q44 | |
| Type of gene | protein-coding | protein-coding | |
| Description | NEDD4-binding protein 2-like 1hypothetical gene CG018 | zinc finger and BTB domain-containing protein 1858 kDa repressor proteintranscriptional repressor RP58translin-associated zinc finger protein 1zinc finger protein 238zinc finger protein C2H2-171 | |
| Modification date | 20180403 | 20180523 | |
| UniProtAcc | Q5TBK1 | Q99592 | |
| Ensembl transtripts involved in fusion gene | ENST00000380130, ENST00000380139, ENST00000530622, ENST00000459716, ENST00000380133, | ENST00000358704, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 4 X 4 X 2=32 |
| # samples | 3 | 5 | |
| ** MAII score | log2(3/4*10)=2.90689059560852 | log2(5/32*10)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: N4BP2L1 [Title/Abstract] AND ZBTB18 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ZBTB18 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 25796446 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE242289 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000380130 | ENST00000358704 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
| In-frame | ENST00000380139 | ENST00000358704 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
| intron-3CDS | ENST00000530622 | ENST00000358704 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
| intron-3CDS | ENST00000459716 | ENST00000358704 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
| In-frame | ENST00000380133 | ENST00000358704 | N4BP2L1 | chr13 | 33002034 | - | ZBTB18 | chr1 | 244217086 | + |
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FusionProtFeatures for N4BP2L1_ZBTB18 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| N4BP2L1 | ZBTB18 |
| Transcriptional repressor that plays a role in variousdevelopmental processes such as myogenesis and brain development.Plays a key role in myogenesis by directly repressing theexpression of ID2 and ID3, 2 inhibitors of skeletal myogenesis.Also involved in controlling cell division of progenitor cells andregulating the survival of postmitotic cortical neurons.Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts byrecruiting chromatin remodeling multiprotein complexes. May alsoplay a role in the organization of chromosomes in the nucleus.{ECO:0000269|PubMed:9756912}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for N4BP2L1_ZBTB18 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_N4BP2L1_ENST00000380130_chr13_33002034_-_ZBTB18_ENST00000358704_chr1_244217086_+_3964nt ATCACATGGCCGGAGAGTCACAAAAACAACAGCTTTGGCCAAGACCGTGACTTCAGTAAAGGGAACCCGGGGCTCTCGCAGCCAGCCCTC CTGCCCATGGAGGACAGTTTCCTTCAATCTTTTGGGAGGCTGAGCCTCCAGCCCCAGCAGCAGCAGCAGCGGCAGCGGCCGCCCCGGCCG CCCCCGCGGGGGACACCTCCTCGCCGCCACAGCTTTAGGAAACACCTCTACCTCCTGCGAGGCCTCCCGGGCTCCGGGAAAACTACACTG GCCAGGTTATGAAGACAGTATGGAGTTTCCAGACCATAGTAGACATTTGCTACAGTGTCTGAGCGAGCAGAGACACCAGGGTTTTCTTTG TGACTGCACTGTTCTGGTGGGAGATGCCCAGTTCCGAGCGCACCGAGCTGTACTGGCTTCATGCAGCATGTATTTCCACCTCTTTTACAA GGACCAGCTGGACAAAAGAGACATTGTTCATCTGAACAGCGACATTGTTACAGCCCCCGCTTTCGCTCTCCTGCTTGAATTCATGTATGA AGGGAAACTCCAGTTCAAAGACTTGCCCATTGAAGACGTGCTAGCAGCTGCCAGTTATCTCCACATGTATGACATTGTCAAAGTCTGCAA AAAGAAGCTGAAAGAGAAAGCCACCACGGAGGCAGACAGCACCAAAAAGGAAGAAGATGCTTCAAGTTGTTCGGACAAAGTCGAGAGTCT CTCCGATGGCAGCAGCCACATAGCAGGCGATTTGCCCAGTGATGAAGATGAAGGAGAAGATGAAAAATTGAACATCCTGCCCAGCAAAAG GGACTTGGCGGCCGAGCCTGGGAACATGTGGATGCGATTGCCCTCAGACTCAGCAGGCATCCCCCAGGCTGGCGGAGAGGCAGAGCCACA CGCCACAGCAGCTGGAAAAACAGTAGCCAGCCCCTGCAGCTCAACAGAGTCTTTGTCCCAGAGGTCTGTCACCTCCGTGAGGGATTCGGC AGATGTTGACTGTGTGCTGGACCTGTCTGTCAAGTCCAGCCTTTCAGGAGTTGAAAATCTGAACAGCTCTTATTTCTCTTCACAGGACGT GCTGAGAAGCAACCTGGTGCAGGTGAAGGTGGAGAAAGAGGCTTCCTGTGATGAGAGTGATGTTGGCACTAATGACTATGACATGGAACA TAGCACTGTGAAAGAAAGTGTGAGCACTAATAACAGGGTACAGTATGAGCCGGCCCATCTGGCTCCCCTGAGGGAGGACTCGGTCTTGAG GGAGCTGGACCGGGAGGACAAAGCCAGTGATGATGAGATGATGACCCCAGAGAGCGAGCGTGTCCAGGTGGAGGGAGGCATGGAGAGCAG TCTGCTCCCCTACGTCTCCAACATCCTGAGCCCCGCGGGCCAGATCTTCATGTGCCCCCTGTGCAACAAGGTCTTCCCCAGCCCCCACAT CCTGCAGATCCACCTGAGCACGCACTTCCGCGAGCAGGACGGCATCCGCAGCAAGCCCGCCGCCGATGTCAACGTGCCCACGTGCTCGCT GTGTGGGAAGACTTTCTCTTGCATGTACACCCTCAAGCGCCACGAGAGGACTCACTCGGGGGAGAAGCCCTACACATGCACCCAGTGCGG CAAGAGCTTCCAGTACTCGCACAACCTGAGCCGCCATGCCGTGGTGCACACCCGCGAGAAGCCGCACGCCTGCAAGTGGTGCGAGCGCAG GTTCACGCAGTCCGGGGACCTGTACAGACACATTCGCAAGTTCCACTGTGAGTTGGTGAACTCCTTGTCGGTCAAAAGCGAAGCACTGAG CTTGCCTACTGTCAGAGACTGGACCTTAGAAGATAGCTCTCAAGAACTTTGGAAATAATTTTATATATATATAAATAATATATATATATA TACATATATATAAATAGATCTCTATATAGTTGTGGTACGGTCTAAAAGCAGTCTTGTTTCCTGGAAATAAAAAGTTGGGATATTAACTTG TTTTTGCACTTTAGAATAGCATGAGAATCTCACTAATTTAGCATTCTGATAAAAGAAACTTTAGAGCAAGTCAGAATAGAGAGGTGTTTT TCCTTTGAGGGGATAGGGGAAGTAAGCCAATAAGAACCTTTTAAACAAATCGTCCTGTCACAAAATGCTTTCATATGGCTTAATTTTGTC AACACTGCATTGTCTTTTGAGCTCTTTTTTCCCCCCCAACAAAGTTTTTTTGTTTTTTGTTTTTTTTTTTAAGTAGAAATTCCCTCCAGT TTTATTAGCCTCTTTATATGTCTCAAATTGCATGAATTTTTTCTGGCTGTTGGAAACCTGAATGCTTTTAGACCCAAATGGAAAATTTCT GAAATGCTGGATTATCTATTTTTAAACAAGCAGTTGACTTAAAACTTTCTGTGGCAACTTCTGGTTTTCTGACAGTTCCCAGTGAGAGAA ATGCTGAAAGTACACTGGGATCACTGGGACACTGTCTTATGAAGGTTTGCTTGGGATGAAAAAGGATATTGCAGCTTCAGCAGTGTTGAA CTGTGTGTTTAAAAATGTGAATTACTGTTATTGTATACTGTAATTGATTACATGGGCTGGGGGGGTGTCAAAGAACTTGACAGGTTGTGT TGATGCTCTTAGTTGAGTCTTGAAAAGTAAATATTAACGCTACAGAAATGCATGAGTTTCAATATATTTTTTGTCTTTGTTTGCATTGTA TAACTTTAACGAGTGAGTTTAAAATTATTTAATTTCCTTAGAAAAATAACACCATTTGGAAAAAAAAACTGGTGTTATGAAGAACGTAAA TGCACTGTTTTTATTTTTATTTTATATAATTTAAATTGACTTTCCCACTGTCTTTAAGTTGAAACTGTTAAGCTGAATAAAAACTTAAGC TGCAAATTGATAACTTCGCTACATAACAAGGAAAATATAAATGTTTACAAACAGCTTAAAGATTTGCATGTGCAGTGTGCATTTATAACA AACTTCTAATTGCACAAAACCCATGCCAGCTCAGAGTTTAGGTGTACACATTTACCCAGTTGAGCGTTCTTAGAATAACTACTGCACAAG TTGACAATAGGTCGTTCTCTCTTTTTTTTTGTTTGCTCCCTTTTTCTTTTTCTCCCCTTCCTCCTTACCCTCCCTCCCTTACTCTCCCCC CCCACCACCACCCTCCACCCCCAACTCATGAAAAGATTCTATGGACTGAAAAAGCCCCAGGCTGAAAGGACTGGACTGCCTTGATTGACA TGGGGAAGGGGGTTAGTAGACTATGTGGATTGCGGCAGCAGAGGCTGCAGCCTAACGTGTGGTTTTAATGACCAGCACGCAAGGCAAAAG CATTTTGCACAGTGTTTGTTTTCCTGTCTTGCACTTACAAATAAGGTCTATGGGAGTAGCATGGAAAACGTTTGCTGTTTTTCCCTTTTT TTTTTAATTGCTTTTGTTTAAAATTTGATCGCCTTAACTACTGTAAACATAGCCTATTTTTGTGCTTAAGATACTGAATGGAAAACTCCA TTGTGTGTTGCTGGACTGTTTTGGAAATATTTGGTTAAATGTGTGTTAATTTGGCTGTAATGGCATTTAAAGCAAACAAACAAACAAAAA AAGCTGTGAAAATGGCCTTGGAGCATTATCTTTAGTTACTTGAAGAGTTTCTAGTTTTTTTAAAATACAGTTTATGTTAAAATAATTTTT ATTAATTTAGAGAAGACAATCAATGTCTGTGAGAAAACGGACTTTCTTTTGGATTTTCTTTTTGTGGTCATTGTGAGTGATTGCTTTTTC CTTTTCTTAGTTTCACATTCTTCCTTTGTTCTAAAACTTAGACTGACATCTAGCTTTGACAATCATAGTATGTTTTATTTTCCTGAGGGG GAATAACTTATAATGCTGTTTAGTTTTGTACTATTGGTGTGTTGGTGAATTTTTAAACTGTGTGCTAACTGCAATAAATTATATGAACTG >In-frame_N4BP2L1_ENST00000380139_chr13_33002034_-_ZBTB18_ENST00000358704_chr1_244217086_+_3919nt CGTGACTTCAGTAAAGGGAACCCGGGGCTCTCGCAGCCAGCCCTCCTGCCCATGGAGGACAGTTTCCTTCAATCTTTTGGGAGGCTGAGC CTCCAGCCCCAGCAGCAGCAGCAGCGGCAGCGGCCGCCCCGGCCGCCCCCGCGGGGGACACCTCCTCGCCGCCACAGCTTTAGGAAACAC CTCTACCTCCTGCGAGGCCTCCCGGGCTCCGGGAAAACTACACTGGCCAGGTTATGAAGACAGTATGGAGTTTCCAGACCATAGTAGACA TTTGCTACAGTGTCTGAGCGAGCAGAGACACCAGGGTTTTCTTTGTGACTGCACTGTTCTGGTGGGAGATGCCCAGTTCCGAGCGCACCG AGCTGTACTGGCTTCATGCAGCATGTATTTCCACCTCTTTTACAAGGACCAGCTGGACAAAAGAGACATTGTTCATCTGAACAGCGACAT TGTTACAGCCCCCGCTTTCGCTCTCCTGCTTGAATTCATGTATGAAGGGAAACTCCAGTTCAAAGACTTGCCCATTGAAGACGTGCTAGC AGCTGCCAGTTATCTCCACATGTATGACATTGTCAAAGTCTGCAAAAAGAAGCTGAAAGAGAAAGCCACCACGGAGGCAGACAGCACCAA AAAGGAAGAAGATGCTTCAAGTTGTTCGGACAAAGTCGAGAGTCTCTCCGATGGCAGCAGCCACATAGCAGGCGATTTGCCCAGTGATGA AGATGAAGGAGAAGATGAAAAATTGAACATCCTGCCCAGCAAAAGGGACTTGGCGGCCGAGCCTGGGAACATGTGGATGCGATTGCCCTC AGACTCAGCAGGCATCCCCCAGGCTGGCGGAGAGGCAGAGCCACACGCCACAGCAGCTGGAAAAACAGTAGCCAGCCCCTGCAGCTCAAC AGAGTCTTTGTCCCAGAGGTCTGTCACCTCCGTGAGGGATTCGGCAGATGTTGACTGTGTGCTGGACCTGTCTGTCAAGTCCAGCCTTTC AGGAGTTGAAAATCTGAACAGCTCTTATTTCTCTTCACAGGACGTGCTGAGAAGCAACCTGGTGCAGGTGAAGGTGGAGAAAGAGGCTTC CTGTGATGAGAGTGATGTTGGCACTAATGACTATGACATGGAACATAGCACTGTGAAAGAAAGTGTGAGCACTAATAACAGGGTACAGTA TGAGCCGGCCCATCTGGCTCCCCTGAGGGAGGACTCGGTCTTGAGGGAGCTGGACCGGGAGGACAAAGCCAGTGATGATGAGATGATGAC CCCAGAGAGCGAGCGTGTCCAGGTGGAGGGAGGCATGGAGAGCAGTCTGCTCCCCTACGTCTCCAACATCCTGAGCCCCGCGGGCCAGAT CTTCATGTGCCCCCTGTGCAACAAGGTCTTCCCCAGCCCCCACATCCTGCAGATCCACCTGAGCACGCACTTCCGCGAGCAGGACGGCAT CCGCAGCAAGCCCGCCGCCGATGTCAACGTGCCCACGTGCTCGCTGTGTGGGAAGACTTTCTCTTGCATGTACACCCTCAAGCGCCACGA GAGGACTCACTCGGGGGAGAAGCCCTACACATGCACCCAGTGCGGCAAGAGCTTCCAGTACTCGCACAACCTGAGCCGCCATGCCGTGGT GCACACCCGCGAGAAGCCGCACGCCTGCAAGTGGTGCGAGCGCAGGTTCACGCAGTCCGGGGACCTGTACAGACACATTCGCAAGTTCCA CTGTGAGTTGGTGAACTCCTTGTCGGTCAAAAGCGAAGCACTGAGCTTGCCTACTGTCAGAGACTGGACCTTAGAAGATAGCTCTCAAGA ACTTTGGAAATAATTTTATATATATATAAATAATATATATATATATACATATATATAAATAGATCTCTATATAGTTGTGGTACGGTCTAA AAGCAGTCTTGTTTCCTGGAAATAAAAAGTTGGGATATTAACTTGTTTTTGCACTTTAGAATAGCATGAGAATCTCACTAATTTAGCATT CTGATAAAAGAAACTTTAGAGCAAGTCAGAATAGAGAGGTGTTTTTCCTTTGAGGGGATAGGGGAAGTAAGCCAATAAGAACCTTTTAAA CAAATCGTCCTGTCACAAAATGCTTTCATATGGCTTAATTTTGTCAACACTGCATTGTCTTTTGAGCTCTTTTTTCCCCCCCAACAAAGT TTTTTTGTTTTTTGTTTTTTTTTTTAAGTAGAAATTCCCTCCAGTTTTATTAGCCTCTTTATATGTCTCAAATTGCATGAATTTTTTCTG GCTGTTGGAAACCTGAATGCTTTTAGACCCAAATGGAAAATTTCTGAAATGCTGGATTATCTATTTTTAAACAAGCAGTTGACTTAAAAC TTTCTGTGGCAACTTCTGGTTTTCTGACAGTTCCCAGTGAGAGAAATGCTGAAAGTACACTGGGATCACTGGGACACTGTCTTATGAAGG TTTGCTTGGGATGAAAAAGGATATTGCAGCTTCAGCAGTGTTGAACTGTGTGTTTAAAAATGTGAATTACTGTTATTGTATACTGTAATT GATTACATGGGCTGGGGGGGTGTCAAAGAACTTGACAGGTTGTGTTGATGCTCTTAGTTGAGTCTTGAAAAGTAAATATTAACGCTACAG AAATGCATGAGTTTCAATATATTTTTTGTCTTTGTTTGCATTGTATAACTTTAACGAGTGAGTTTAAAATTATTTAATTTCCTTAGAAAA ATAACACCATTTGGAAAAAAAAACTGGTGTTATGAAGAACGTAAATGCACTGTTTTTATTTTTATTTTATATAATTTAAATTGACTTTCC CACTGTCTTTAAGTTGAAACTGTTAAGCTGAATAAAAACTTAAGCTGCAAATTGATAACTTCGCTACATAACAAGGAAAATATAAATGTT TACAAACAGCTTAAAGATTTGCATGTGCAGTGTGCATTTATAACAAACTTCTAATTGCACAAAACCCATGCCAGCTCAGAGTTTAGGTGT ACACATTTACCCAGTTGAGCGTTCTTAGAATAACTACTGCACAAGTTGACAATAGGTCGTTCTCTCTTTTTTTTTGTTTGCTCCCTTTTT CTTTTTCTCCCCTTCCTCCTTACCCTCCCTCCCTTACTCTCCCCCCCCACCACCACCCTCCACCCCCAACTCATGAAAAGATTCTATGGA CTGAAAAAGCCCCAGGCTGAAAGGACTGGACTGCCTTGATTGACATGGGGAAGGGGGTTAGTAGACTATGTGGATTGCGGCAGCAGAGGC TGCAGCCTAACGTGTGGTTTTAATGACCAGCACGCAAGGCAAAAGCATTTTGCACAGTGTTTGTTTTCCTGTCTTGCACTTACAAATAAG GTCTATGGGAGTAGCATGGAAAACGTTTGCTGTTTTTCCCTTTTTTTTTTAATTGCTTTTGTTTAAAATTTGATCGCCTTAACTACTGTA AACATAGCCTATTTTTGTGCTTAAGATACTGAATGGAAAACTCCATTGTGTGTTGCTGGACTGTTTTGGAAATATTTGGTTAAATGTGTG TTAATTTGGCTGTAATGGCATTTAAAGCAAACAAACAAACAAAAAAAGCTGTGAAAATGGCCTTGGAGCATTATCTTTAGTTACTTGAAG AGTTTCTAGTTTTTTTAAAATACAGTTTATGTTAAAATAATTTTTATTAATTTAGAGAAGACAATCAATGTCTGTGAGAAAACGGACTTT CTTTTGGATTTTCTTTTTGTGGTCATTGTGAGTGATTGCTTTTTCCTTTTCTTAGTTTCACATTCTTCCTTTGTTCTAAAACTTAGACTG ACATCTAGCTTTGACAATCATAGTATGTTTTATTTTCCTGAGGGGGAATAACTTATAATGCTGTTTAGTTTTGTACTATTGGTGTGTTGG >In-frame_N4BP2L1_ENST00000380133_chr13_33002034_-_ZBTB18_ENST00000358704_chr1_244217086_+_3919nt CGTGACTTCAGTAAAGGGAACCCGGGGCTCTCGCAGCCAGCCCTCCTGCCCATGGAGGACAGTTTCCTTCAATCTTTTGGGAGGCTGAGC CTCCAGCCCCAGCAGCAGCAGCAGCGGCAGCGGCCGCCCCGGCCGCCCCCGCGGGGGACACCTCCTCGCCGCCACAGCTTTAGGAAACAC CTCTACCTCCTGCGAGGCCTCCCGGGCTCCGGGAAAACTACACTGGCCAGGTTATGAAGACAGTATGGAGTTTCCAGACCATAGTAGACA TTTGCTACAGTGTCTGAGCGAGCAGAGACACCAGGGTTTTCTTTGTGACTGCACTGTTCTGGTGGGAGATGCCCAGTTCCGAGCGCACCG AGCTGTACTGGCTTCATGCAGCATGTATTTCCACCTCTTTTACAAGGACCAGCTGGACAAAAGAGACATTGTTCATCTGAACAGCGACAT TGTTACAGCCCCCGCTTTCGCTCTCCTGCTTGAATTCATGTATGAAGGGAAACTCCAGTTCAAAGACTTGCCCATTGAAGACGTGCTAGC AGCTGCCAGTTATCTCCACATGTATGACATTGTCAAAGTCTGCAAAAAGAAGCTGAAAGAGAAAGCCACCACGGAGGCAGACAGCACCAA AAAGGAAGAAGATGCTTCAAGTTGTTCGGACAAAGTCGAGAGTCTCTCCGATGGCAGCAGCCACATAGCAGGCGATTTGCCCAGTGATGA AGATGAAGGAGAAGATGAAAAATTGAACATCCTGCCCAGCAAAAGGGACTTGGCGGCCGAGCCTGGGAACATGTGGATGCGATTGCCCTC AGACTCAGCAGGCATCCCCCAGGCTGGCGGAGAGGCAGAGCCACACGCCACAGCAGCTGGAAAAACAGTAGCCAGCCCCTGCAGCTCAAC AGAGTCTTTGTCCCAGAGGTCTGTCACCTCCGTGAGGGATTCGGCAGATGTTGACTGTGTGCTGGACCTGTCTGTCAAGTCCAGCCTTTC AGGAGTTGAAAATCTGAACAGCTCTTATTTCTCTTCACAGGACGTGCTGAGAAGCAACCTGGTGCAGGTGAAGGTGGAGAAAGAGGCTTC CTGTGATGAGAGTGATGTTGGCACTAATGACTATGACATGGAACATAGCACTGTGAAAGAAAGTGTGAGCACTAATAACAGGGTACAGTA TGAGCCGGCCCATCTGGCTCCCCTGAGGGAGGACTCGGTCTTGAGGGAGCTGGACCGGGAGGACAAAGCCAGTGATGATGAGATGATGAC CCCAGAGAGCGAGCGTGTCCAGGTGGAGGGAGGCATGGAGAGCAGTCTGCTCCCCTACGTCTCCAACATCCTGAGCCCCGCGGGCCAGAT CTTCATGTGCCCCCTGTGCAACAAGGTCTTCCCCAGCCCCCACATCCTGCAGATCCACCTGAGCACGCACTTCCGCGAGCAGGACGGCAT CCGCAGCAAGCCCGCCGCCGATGTCAACGTGCCCACGTGCTCGCTGTGTGGGAAGACTTTCTCTTGCATGTACACCCTCAAGCGCCACGA GAGGACTCACTCGGGGGAGAAGCCCTACACATGCACCCAGTGCGGCAAGAGCTTCCAGTACTCGCACAACCTGAGCCGCCATGCCGTGGT GCACACCCGCGAGAAGCCGCACGCCTGCAAGTGGTGCGAGCGCAGGTTCACGCAGTCCGGGGACCTGTACAGACACATTCGCAAGTTCCA CTGTGAGTTGGTGAACTCCTTGTCGGTCAAAAGCGAAGCACTGAGCTTGCCTACTGTCAGAGACTGGACCTTAGAAGATAGCTCTCAAGA ACTTTGGAAATAATTTTATATATATATAAATAATATATATATATATACATATATATAAATAGATCTCTATATAGTTGTGGTACGGTCTAA AAGCAGTCTTGTTTCCTGGAAATAAAAAGTTGGGATATTAACTTGTTTTTGCACTTTAGAATAGCATGAGAATCTCACTAATTTAGCATT CTGATAAAAGAAACTTTAGAGCAAGTCAGAATAGAGAGGTGTTTTTCCTTTGAGGGGATAGGGGAAGTAAGCCAATAAGAACCTTTTAAA CAAATCGTCCTGTCACAAAATGCTTTCATATGGCTTAATTTTGTCAACACTGCATTGTCTTTTGAGCTCTTTTTTCCCCCCCAACAAAGT TTTTTTGTTTTTTGTTTTTTTTTTTAAGTAGAAATTCCCTCCAGTTTTATTAGCCTCTTTATATGTCTCAAATTGCATGAATTTTTTCTG GCTGTTGGAAACCTGAATGCTTTTAGACCCAAATGGAAAATTTCTGAAATGCTGGATTATCTATTTTTAAACAAGCAGTTGACTTAAAAC TTTCTGTGGCAACTTCTGGTTTTCTGACAGTTCCCAGTGAGAGAAATGCTGAAAGTACACTGGGATCACTGGGACACTGTCTTATGAAGG TTTGCTTGGGATGAAAAAGGATATTGCAGCTTCAGCAGTGTTGAACTGTGTGTTTAAAAATGTGAATTACTGTTATTGTATACTGTAATT GATTACATGGGCTGGGGGGGTGTCAAAGAACTTGACAGGTTGTGTTGATGCTCTTAGTTGAGTCTTGAAAAGTAAATATTAACGCTACAG AAATGCATGAGTTTCAATATATTTTTTGTCTTTGTTTGCATTGTATAACTTTAACGAGTGAGTTTAAAATTATTTAATTTCCTTAGAAAA ATAACACCATTTGGAAAAAAAAACTGGTGTTATGAAGAACGTAAATGCACTGTTTTTATTTTTATTTTATATAATTTAAATTGACTTTCC CACTGTCTTTAAGTTGAAACTGTTAAGCTGAATAAAAACTTAAGCTGCAAATTGATAACTTCGCTACATAACAAGGAAAATATAAATGTT TACAAACAGCTTAAAGATTTGCATGTGCAGTGTGCATTTATAACAAACTTCTAATTGCACAAAACCCATGCCAGCTCAGAGTTTAGGTGT ACACATTTACCCAGTTGAGCGTTCTTAGAATAACTACTGCACAAGTTGACAATAGGTCGTTCTCTCTTTTTTTTTGTTTGCTCCCTTTTT CTTTTTCTCCCCTTCCTCCTTACCCTCCCTCCCTTACTCTCCCCCCCCACCACCACCCTCCACCCCCAACTCATGAAAAGATTCTATGGA CTGAAAAAGCCCCAGGCTGAAAGGACTGGACTGCCTTGATTGACATGGGGAAGGGGGTTAGTAGACTATGTGGATTGCGGCAGCAGAGGC TGCAGCCTAACGTGTGGTTTTAATGACCAGCACGCAAGGCAAAAGCATTTTGCACAGTGTTTGTTTTCCTGTCTTGCACTTACAAATAAG GTCTATGGGAGTAGCATGGAAAACGTTTGCTGTTTTTCCCTTTTTTTTTTAATTGCTTTTGTTTAAAATTTGATCGCCTTAACTACTGTA AACATAGCCTATTTTTGTGCTTAAGATACTGAATGGAAAACTCCATTGTGTGTTGCTGGACTGTTTTGGAAATATTTGGTTAAATGTGTG TTAATTTGGCTGTAATGGCATTTAAAGCAAACAAACAAACAAAAAAAGCTGTGAAAATGGCCTTGGAGCATTATCTTTAGTTACTTGAAG AGTTTCTAGTTTTTTTAAAATACAGTTTATGTTAAAATAATTTTTATTAATTTAGAGAAGACAATCAATGTCTGTGAGAAAACGGACTTT CTTTTGGATTTTCTTTTTGTGGTCATTGTGAGTGATTGCTTTTTCCTTTTCTTAGTTTCACATTCTTCCTTTGTTCTAAAACTTAGACTG ACATCTAGCTTTGACAATCATAGTATGTTTTATTTTCCTGAGGGGGAATAACTTATAATGCTGTTTAGTTTTGTACTATTGGTGTGTTGG |
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FusionGenePPI for N4BP2L1_ZBTB18 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for N4BP2L1_ZBTB18 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for N4BP2L1_ZBTB18 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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