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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 22778

FusionGeneSummary for MTMR10_TSPAN14

check button Fusion gene summary
Fusion gene informationFusion gene name: MTMR10_TSPAN14
Fusion gene ID: 22778
HgeneTgene
Gene symbol

MTMR10

TSPAN14

Gene ID

54893

81619

Gene namemyotubularin related protein 10tetraspanin 14
Synonyms-DC-TM4F2|TM4SF14
Cytomap

15q13.3

10q23.1

Type of geneprotein-codingprotein-coding
Descriptionmyotubularin-related protein 10tetraspanin-14tetraspanin similar to TM4SF9transmembrane 4 superfamily member 14tspan-14
Modification date2018051920180523
UniProtAcc

Q9NXD2

Q8NG11

Ensembl transtripts involved in fusion geneENST00000435680, ENST00000425768, 
ENST00000314404, ENST00000563714, 
ENST00000429989, ENST00000481124, 
ENST00000372164, ENST00000372158, 
ENST00000341863, ENST00000372156, 
ENST00000265450, 
Fusion gene scores* DoF score1 X 1 X 1=17 X 8 X 2=112
# samples 18
** MAII scorelog2(1/1*10)=3.32192809488736log2(8/112*10)=-0.485426827170242
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MTMR10 [Title/Abstract] AND TSPAN14 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1BG389369MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000435680ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000435680ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
In-frameENST00000425768ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000425768ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-3CDSENST00000314404ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5UTR-intronENST00000314404ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
In-frameENST00000563714ENST00000429989MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000481124MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372164MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372158MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000341863MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000372156MTMR10chr15

31266517

-TSPAN14chr10

82264482

+
5CDS-intronENST00000563714ENST00000265450MTMR10chr15

31266517

-TSPAN14chr10

82264482

+

Top

FusionProtFeatures for MTMR10_TSPAN14


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MTMR10

Q9NXD2

TSPAN14

Q8NG11

Probable pseudophosphatase. Contains a Glu residueinstead of a conserved Cys residue in the dsPTPase catalytic loopwhich renders it catalytically inactive as a phosphatase(Potential). {ECO:0000305}. Regulates maturation and trafficking of thetransmembrane metalloprotease ADAM10 (PubMed:26668317,PubMed:23035126, PubMed:26686862). Negatively regulates ADAM10-mediated cleavage of GP6 (By similarity). Promotes ADAM10-mediatedcleavage of CDH5 (By similarity). {ECO:0000250|UniProtKB:Q8QZY6,ECO:0000269|PubMed:23035126, ECO:0000269|PubMed:26668317,ECO:0000269|PubMed:26686862}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+412254_27027271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+41239_6127271Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+41283_9227271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+311254_27027271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+31139_6127271Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+31183_9227271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+081_17-20254Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+08254_270-20254Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+0839_61-20254Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+0883_92-20254Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+19254_27027271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+1939_6127271Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+1983_9227271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+061_17-42148Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+06254_270-42148Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+0639_61-42148Topological domainExtracellular
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+0683_92-42148Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+412233_25327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+41262_8227271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+41293_11327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+311233_25327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+31162_8227271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+31193_11327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+0818_38-20254TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+08233_253-20254TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+0862_82-20254TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372164+0893_113-20254TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+19233_25327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+1962_8227271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+1993_11327271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+0618_38-42148TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+06233_253-42148TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+0662_82-42148TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000481124+0693_113-42148TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMTMR10chr15:31266517chr10:82264482ENST00000425768-515198_2131581270Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000435680-516198_213158778Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000563714-515198_21376452Compositional biasNote=Poly-Gly
HgeneMTMR10chr15:31266517chr10:82264482ENST00000425768-515221_6611581270DomainMyotubularin phosphatase
HgeneMTMR10chr15:31266517chr10:82264482ENST00000435680-516221_661158778DomainMyotubularin phosphatase
HgeneMTMR10chr15:31266517chr10:82264482ENST00000563714-515221_66176452DomainMyotubularin phosphatase
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+4121_1727271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+3111_1727271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+191_1727271Topological domainCytoplasmic
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372156+41218_3827271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000372158+31118_3827271TransmembraneHelical
TgeneTSPAN14chr15:31266517chr10:82264482ENST00000429989+1918_3827271TransmembraneHelical


Top

FusionGeneSequence for MTMR10_TSPAN14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MTMR10_ENST00000435680_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_244aa
LAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQD
WVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQ

>In-frame_MTMR10_ENST00000425768_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_244aa
LAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQD
WVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQ

>In-frame_MTMR10_ENST00000563714_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_244aa
LAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQD
WVRDRFREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQ


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MTMR10_ENST00000435680_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_732nt
TTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGCTGTCCGACCTCACCAAAGTGACCCGGATGCAT
GGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGTTCGCCGGCTGCGTGGGGGCTCTGCGGGAGAAT
ATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGGCTGTGGCCGTGCTGGCCTTCCTGTTCCAGGAC
TGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACGATATCGATCTGCAAAACCTCATCGACTCCCTT
CAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCTACTTCAATTGCAGCGGTGCCAGCTACAGCCGA
GAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGAACACACAGTGTGGATATGATGTCAGGATTCAG
CTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAAGCTGGCTCCCGCGGAACATTTACATTGTGGCT
GGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGCTGATCTCAGACATCGAGGCAGTGAAGGCCGGC

>In-frame_MTMR10_ENST00000425768_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_732nt
TTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGCTGTCCGACCTCACCAAAGTGACCCGGATGCAT
GGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGTTCGCCGGCTGCGTGGGGGCTCTGCGGGAGAAT
ATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGGCTGTGGCCGTGCTGGCCTTCCTGTTCCAGGAC
TGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACGATATCGATCTGCAAAACCTCATCGACTCCCTT
CAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCTACTTCAATTGCAGCGGTGCCAGCTACAGCCGA
GAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGAACACACAGTGTGGATATGATGTCAGGATTCAG
CTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAAGCTGGCTCCCGCGGAACATTTACATTGTGGCT
GGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGCTGATCTCAGACATCGAGGCAGTGAAGGCCGGC

>In-frame_MTMR10_ENST00000563714_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_732nt
TTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGCTGTCCGACCTCACCAAAGTGACCCGGATGCAT
GGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGTTCGCCGGCTGCGTGGGGGCTCTGCGGGAGAAT
ATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGGCTGTGGCCGTGCTGGCCTTCCTGTTCCAGGAC
TGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACGATATCGATCTGCAAAACCTCATCGACTCCCTT
CAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCTACTTCAATTGCAGCGGTGCCAGCTACAGCCGA
GAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGAACACACAGTGTGGATATGATGTCAGGATTCAG
CTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAAGCTGGCTCCCGCGGAACATTTACATTGTGGCT
GGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGCTGATCTCAGACATCGAGGCAGTGAAGGCCGGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MTMR10_ENST00000435680_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_16451nt
AGAAAGGGCCTGGGCGGCCGCACTGAGAGCTTTACGCCCGGAGGCGTCGGCGCTGCCACTGGCCCGCGACGGGAACGGGGCGAAAAGGCG
GCGGCACCATGTTCTCCCTCAAGCCGCCCAAACCCACCTTCAGGTCCTACCTCCTGCCACCGCCCCAGACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA

>In-frame_MTMR10_ENST00000425768_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_16451nt
AGAAAGGGCCTGGGCGGCCGCACTGAGAGCTTTACGCCCGGAGGCGTCGGCGCTGCCACTGGCCCGCGACGGGAACGGGGCGAAAAGGCG
GCGGCACCATGTTCTCCCTCAAGCCGCCCAAACCCACCTTCAGGTCCTACCTCCTGCCACCGCCCCAGACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA

>In-frame_MTMR10_ENST00000563714_chr15_31266517_-_TSPAN14_ENST00000429989_chr10_82264482_+_16451nt
CTCCTCTGCGCTTCCGTGGAGCCTCCAGGCCGACCCCCGGGAACTGGAGGACCCCAGGAGGCTGCGCGCGTCTCCCTGCCCACAGCAGCG
CGGCTGCCTGATTCCCGGCGCCGCGAAATGCGCCTTCTCGGGAGCCCCCACTGGCTCGGCGAAAACTTACTGACGATAAGATCAATTCGG
AACCGAAGATTAAAAAACTGGAGCCAGTCCTTTTGCCAGGAGAAATTGTCGTAAATGAAGTCAATTTTGTGAGAAAATGCATTGCAACAG
ACACAAGCCAGTACGATTTGTGGGGAAAGCTGATATGCAGTAACTTCAAAATCTCCTTTATTACAGATGACCCAATGCCATTACAGAAAT
TCCATTACAGAAACCTTCTTCTTGGTGAACACGATGTCCCTTTAACATGTATTGAGCAAATTGTCACAGTAAACGACCACAAGAGGAAGC
AGAAAGTCCTAGGCCCCAACCAGAAACTGAAATTTAATCCAACAGAGTTAATTATTTATTGTAAAGATTTCAGAATTGTCAGATTTCGCT
TTGATGAATCAGGTCCCGAAAGTGCTAAAAAGTTGGCTGGAGTTGTCTTCCTTGGAGTCGGGCTGTGGGCATGGAGCGAAAAGGGTGTGC
TGTCCGACCTCACCAAAGTGACCCGGATGCATGGAATCGACCCTGTGGTGCTGGTCCTGATGGTGGGCGTGGTGATGTTCACCCTGGGGT
TCGCCGGCTGCGTGGGGGCTCTGCGGGAGAATATCTGCTTGCTCAACTTTTTCTGTGGCACCATCGTGCTCATCTTCTTCCTGGAGCTGG
CTGTGGCCGTGCTGGCCTTCCTGTTCCAGGACTGGGTGAGGGACCGGTTCCGGGAGTTCTTCGAGAGCAACATCAAGTCCTACCGGGACG
ATATCGATCTGCAAAACCTCATCGACTCCCTTCAGAAAGCTAACCAGTGCTGTGGCGCATATGGCCCTGAAGACTGGGACCTCAACGTCT
ACTTCAATTGCAGCGGTGCCAGCTACAGCCGAGAGAAGTGCGGGGTCCCCTTCTCCTGCTGCGTGCCAGATCCTGCGCAAAAAGTTGTGA
ACACACAGTGTGGATATGATGTCAGGATTCAGCTGAAGAGCAAGTGGGATGAGTCCATCTTCACGAAAGGCTGCATCCAGGCGCTGGAAA
GCTGGCTCCCGCGGAACATTTACATTGTGGCTGGCGTCTTCATCGCCATCTCGCTGTTGCAGATATTTGGCATCTTCCTGGCAAGGACGC
TGATCTCAGACATCGAGGCAGTGAAGGCCGGCCATCACTTCTGAGGAGCAGAGTTGAGGGAGCCGAGCTGAGCCACGCTGGGAGGCCAGA
GCCTTTCTCTGCCATCAGCCCTACGTCCAGAGGGAGAGGAGCCGACACCCCCAGAGCCAGTGCCCCATCTTAAGCATCAGCGTGACGTGA
CCTCTCTGTTTCTGCTTGCTGGTGCTGAAGACCAAGGGTCCCCCTTGTTACCTGCCCAAACTTGTGACTGCATCCCTCTGGAGTCTACCC
AGAGACAGAGAATGTGTCTTTATGTGGGAGTGGTGACTCTGAAAGACAGAGAGGGCTCCTGTGGCTGCCAGGAGGGCTTGACTCAGACCC
CCTGCAGCTCAAGCATGTCTGCAGGACACCCTGGTCCCCTCTCCACTGGCATCCAGACATCTGCTTTGGGTCATCCACATCTGTGGGTGG
GCCGTGGGTAGAGGGACCCACAGGCGTGGACAGGGCATCTCTCTCCATCAAGCAAAGCAGCATGGGGGCCTGCCCGTAACGGGAGGCGGA
CGTGGCCCCGCTGGGCCTCTGAGTGCCAGCGCAGTCTGCTGGGACATGCACATATCAGGGGTTGTTTGCAGGATCCTCAGCCATGTTCAA
GTGAAGTAAGCCTGAGCCAGTGCGTGGACTGGTGCCACGGGAGTGCCTTGTCCACTGTCCCCCTGTGTCCACCAGCTATTCTCCTGGCGC
CGGAACTGCCTCTGGTCTTGATAGCATTAAGCCCTGATGGCGCCGGTGGCGCGGTGGGCATGGTTCTTCACTGAGAGCCGGCTCTCCTTT
TCTTAAAGTGTGTAAATAGTTTATTTATAGGGGTAAGAATGTTCTCACACCATTTCACTTCCTCTTCCTCTCCTCCAGCATTCTCCTCTG
AGCAGCCTTAGATAGTGTCCATGGCTGGAGCCGACCCTTTGAGTCCCCTTGAGTGTCTTAAGAACCAGCCCACAACAGCCTCTCTTTCTC
CTCCACATACTGCAGCCTCCCTCCATGCATCCCACATACAAGCACTCCCCCACTCCCCAGCGTGGCCTCACTGTCTTCTGGTCTTGGTGC
TACTGAAATTGTCACCCAGAATTTGAATCCTGACCCTCCCCACTGCAAGCCCAGGGAGCCCCAGCCCAAGATGGCCAGCCTGAAACTGTT
GGCCAGGGCTCCTCTTGTGGCCATGTACCCAGGGCTGGCTGGCCTGCCATTTGCCTCTCCCCGGAGACAGCCGTTCTTCTGCAACCACAC
CCCGTGCCTAGCCACAACCCCAGGCTGCAGCTGCTCAGAAGCTCCAGGCATTTTGTTTCTGGTGACCGCCCCTAATGGGATATCGGTGAT
CACTGGTCCACCCTTCCTGTCAGGGCTTTTCTGGGGCTGCTCTTGGAAATGAAGTCTTAAGTACTGAATAACTCCCCTGGGGATAGCTGG
GGCATTTGTCTAGCTGGGCTACTTTCTAACACTTTGCCATAGCTCAGACCACTTCTCATCGTTCAGGGATGGACTGCAACCTTAATTTAC
TTGCCGGAGTGTACATTCTAGTGTGGTGTATACTGGTGGCTGTTGATGATGATTTTTTTTTTTTTACACAATTCTCTGTAGACTAGGAGA
AGAATGCTTGTGTTTTTCGGAAGTGTGATGCTTCTCTTTGACTGCCAAACTCTTTTATGGAATATATCTTTATATTAATGCTGTTTTGGT
CATTTTTGTTTGGGGTCACTATTGAGATATTGCTAAGCATCTCAGTGGTAAACGCGGCTGCCAGAGGAACCAAGGGATAGGGTATGTAGA
CCTTACAGAAGGATGGATGGTAAAGGCAGTCCATCATCAGCACAATCTGACTTACATTTCATTGAGTAATTTTTTTTTTTTTTAAGATTC
TGTATGGCAGCACTTTCAGTTGCCCTTGTGTGCCGGCCACAGCCGCACAAGTTGGCTTGTGGTTTATCCCCCGCTATAAGTGAGAGCTGG
AGAAACTTCAACTCCATAGGTCTAGAGGAAACATTGTTTTAGGTTATTTCTGTCCACCCCTGTGCGATACTATTTATTGATCCAAGCAGA
AGAGCTTGGGGACACTGAGTCGAAGTGGGGACATGGGATTGAAGCCTGGGCACTGCTGCTGCATGAGCTGTGTGTCCTGGGTGTGCCGGC
CTTTCTGTGAAGGGGGTTGGTGGCAGTGCCCACCTCACTAGATGCCTCTGACCCAGCCTCCCCTGGGGGAGTGGGTGGCCACAGACCCTC
CCTGCCAGAGCTCCTGGAAGGCTCCTGCAGGCCTGACCCATCTATTCCTGTAGACCTGGTTTAGGATGAAGTCTCGGTGCGATTTTTGCA
GAGTTGGGTTTATCTTTCAACTATAGACCCTTCTGGCTGTTCTCAGCCATATCATGTGACTCTGAATAGTTGGATGAGGAATGGAAAGAA
AGCAAGGATGAGAGCCGGTCACGTGGCAGTCTCCGCCCAGCATCGGCTGTCCGCACAGAGGCACAGGGCAGGCCTCCTGTGCACTCCCCA
CCTAGCACTGGCCTGTCCTGAATCCCCGCCTTCCCTGGTTGGAGGCCAGCTGTGGCATTTGCACCCTCTTCTCACCTCACCATGCACATG
CTAACTTTAAAGCCTTGGGGTCTTTCCTGTACCCCCTCCTCAACCCTGGTCCACCCCCTCTCAGGATCTTGTCAACGTTATTTTTCCTGT
CCCGTCTTCCTATCGCTGGCCTTCCTTTCCCATCCTAAAAACTTGCCGAGGCCCTATGGCTCCCTCCCTTTCTTTCCCAGGCAGCTTCTT
ATCTGGGCTGTCTGTACCCCTTCCTTTGCACCACCCACCATGCCCCACGTAGCTGAAAGCTGCTTATCCCAATTGTCAACTCTGGCCTTC
TTCAGCCTCTGTAGCACCAGACACTGCACCTCCTGAATGTCCTCTGCTTCTCTGCTTCAGAGGCCCAGGCTCGCCAGTTCTCTGACCTCT
CCCATATGTCTGCTTAGGACTCTGCTGCAGCTGTCCTCACCAGCCTCCGGGGAATCCCACTACCCACAGGGCAGGGCTGTGGGCTGGGCT
GAAAAACCATCTGCATGGTCCACAAGAAGCCTGGCACTGGGTTTCCCCATGAATAACAATGAAAATTAATGGATGCACAACCTTCCTGGA
ACGTGGAATTTCTCTGGGAGATTCCATGCAGAGGCCACTGGGGAGGTGGCAGGCATGCATGTGACTGTAGGTGGCTGCAGTGTTGGAAGG
CTCCCAGCAGAGCAGAGAGGGTGTCAGTCTCATCAGGGAACCCACCTGATGGCTTCTCAGCCAGCAGTCTCAGAGGAACATAGACGACTG
CTGAGAAAGGAGGGAGGCAGCAGTGGTCCCAGCACCTGAGGCATCCTGCTGTCATGGGAAGGTCTCCGCCCAAATGTCAGATGCATCAGC
CTGTCACCCGCTGGTCCAGAGCTTTCAGCTGTACTGGTAGGGGGTGGGTGGTGGAGTGCTGAATGACCTTCACAGGTGGGCCTTTCCAGC
TCTAGGGTCTTACGGGTGTCGGTCCACAGAACCACGGTTTTTAGGTTGTGTGTCCGGGGCTATGGGAACCTGTCCCCCATGATGGATCTT
GGTAGAGACACTTCCCTCTGTCATCGTGCCCAGGAGGATGCTGCAGGTGACTACCTGCAGCCCTGTTCTCATTCATTTGGATGCCCTCCA
GAAATCTGGGGAGCCATACACCTTTAGAGCCTTTTTTGCTCCTTATCAAGTTGGCAAGGCTTGGCCAATTCCTGTTCAAGGCTGCATTAA
AGGCATGTTCACCATCCTGGCTAATACGGTGAAACCCCTTCTCTACTAAAAATACAAAAAAATTAGCCGGGCTTGGTGGCGGGTGCCTGT
AGTCCCAGCTACTCCGGAGGCTGAGGCAGGGGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCACACCACTGCACTC
CAGCCTGGGCTCAAAAAAGAAAAAAAAAAAAAAAAAAAGGCCCGTTCATTCTCAAATGCTTTTGGCGTCTCCAGGGTGCCTCAGGAAAAC
ATGAAGTGGGCATTGTAGAACTTGGGGCTACTGTGTAACTTTGGAAGAAAAAGTTAAGGGTACTTTTAAGTGGATACTGTTTTGATGAAA
TTGCCAACTTCAGGGAGCCCAGCTTGGAGAAGGAGGACGTGAGTATTCCTTACAAGGCTCCGAAACAATTCTTTCTTCACTTAGTTTTCT
TTCTGTGCTCTGCATCTTATATTCCAGCAGGGTCTTCCAATGCATGGTTTAATAACTACTAGAACTGGCCAGGTGCAGTGGCTCACGCCT
GTAATCCCAGAACTTTGGGAGGCTAAGACAGGCAGATCACTTGAGGCCAGGAGTTCGAGACCAGCCTGGACAACATGGTGATACCCAGTT
TCTACTAAAAATACAAAAATTAGTCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCGCTTGAA
CCCGGGAGACAGAGGTTGCAACGAGCCAAGATCGAGCCACTGCGCTCCGGCCTGGGTGACAGGAGACTCCATCTCAAAAAATAAAATTAA
AAAAAAACTACTACAATAAATTATCACCTTGGACTGTATAAAACAACTTTTAAACTAGTCTTTTTAAAAAGTACACTTAAATAAAAATCT
AAACATAAGAGAATGTAAAGTGAAAAGTGAAAGTATGTCTTCTGTTACGCAGAGGTAACTACTATTAGGAATCCTTCCTGAAAATGTCCA
TGCATCTACTCAGGTCATCACACCCATGGAATCATTTTACATACTATTTTATGAGTGTTACTTAATATACTGATCCACAGTGCGTTTTCA
CGGTCACGCCATCAGTTGTAGGAGTGTGCCAAGAACAGATGGGCCTTGCCTTTGTACCAGAGGAGTCCATTTACAGTTGCAGGTAATAGA
AAACCCAATTCAGACTGGCCTAAACAATGAGGGGAGGTTTTGGCTCTTGAAACTGGAAAGTCCCAAGGTGGGGTGAGTTTCAGGTTTGGG
TTGATCCAAGTGGCTCAGTGACGTCAACAGGATCTTGTTTCCATTTCTCTGCCTTCCACAGCCTCCCCTTCATCTATGGTGGAGGGAAGG
AGTCTACCACAGACAAACCCCGAGCCTCCCCCTGATGGGTGGTGTGGTGGTGAAGCCAGCAAGGGAAGGGATCCCCGGACACACCCCTCC
TCATGCTTTATCCCACTGAAACCATGCGGCTGTGAAATGCAGCATCCTCCAGGAGGGGGATGAAGGCCGGGGATGCTGTCAGCTATTGCC
ATTGCACTTCTGTGGATGGGTGTTACAGTTTTTTGCAGGGTTTTGCACTTACAAGGACATATATATATATATATAAACTACAGTGTTATT
GGAATTGCTTCTTACAGTTTGTAAGAAAAAAACATGTTTTTAGAGGAGTTCTCCTGGGAGGTGGGATCACATTTTTTTTTTTTTTTTTTT
TTGAGACGGAGTCTCGCTCTGTGGCCCAGGCGGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCAT
TCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGGGGATCACATTTTAATAAGTAGGTACTCAGGGCTGGGGTGTACCTGTTGCTGCCTGACCACTGCTGG
TGTGTGTGGGTATAAGGTGACAAAACCTCCTACCCCTGTGAGGTTGTTTCAAGGATTAAATGAGTTGAGATGGGTAAGCATCTAACAAAG
ATCCAGATTATTTAGTATGCATCCCCTGAATTATTGCTAACATAATTTTAATGATTGGGGAATTTTATCTGTGGCTGCCAGTCCCTACGA
GAGAGCTGCCTGGGTCACATGTCAGATAGCTCAAGCTTTGAATCACTGAAACGAAACGGTCCACTTCCCTGTCCCTTTAGGAACAAGGCT
TCGAGGTCTGTGGCAAGCCTCAGCAGGCATTTGGAGTTCAAGGTCTGTTCTCTTTCTGTGCCATAGAGGTGGGGAGACAAGGTAGGGTGT
TGCTTCTTGCCTGGAGCGCAGATGCTACCAGAAACCAACACAACCAAAGTTGCCCGGGAGCCCCCAGAAGCAGCAGAGTGGCCATCAACT
GCCAAGGGGCCAGGGTAGGCCACAGAGGCCTGGGGCCCAGGAGGGATGGTCTGTGGGGAGAAAGGGGATTATTGTGAACATCAACGCTGG
GGATAATGTGCCCTGAAGACAGCAGCATATCACGTTTGGACGGTTGGTGGACCCCATCTGGTCCCACTCATAAGGAGAACAGAGGCCCTG
GGGTGTGCTGGGACTTGCCTGAGGCCTCAGACCGGGACTGGGTGCTCCTCCGCACCTCCTATGAGGGAGGGTGTCCGTGTCTGTGAGGAC
AGCTCAGCAGGGCTGGGAACCTGGGGGCAGTGCTGGGGGACATGTGTGAGACTAGCGTGTGTGGGCCTTGCTCGGCTTGCCCTGGTGCCC
TGAGAAAAACCTGGTATTTGAAAATACACATGGACTGCTGGAAGGTCAGGAAATCCAGGGTTTTGTTCTGAGGCAGTGGAAGTGTTACCG
TGAGCCTGTGTTGGCCTCTCTCCTCACTCCACCTGCAGCCAATTCAGCCACACTGCCTTTGCATGGAACCCAGGGTTGCAGGCCGCGTGT
GTAGATGCTGATTTAGGCCCAAGCACTCAGCTGTCAGCAGGAAGGACCATAGTGTTTTCTTCTAGTTTTAGATATGCACTCGTTCTGTGT
TTTAAAGTCACAGCTGTGAGCCAATATGGGAAGAAGTGAAGTGGCCTCTAGGAGGGACTGAGCACCCTGTCCTTGGAGGTATGCAAGCCC
AGGCTACACCCTTCCTGTCTGGGATGATATGGCTGGGGGTGGGCTTTGTGCTGCGTGGACCATGGCAAGCCTTTCCATCTCTGAGAGGTA
GTGGTCCTTCCCGTGCCTTCTGTTAAAGATAATTTTTTAAAAAAAGGCATAACTCATATATATTACATGTACACATGTCAAAGATTTTAT
TTAACTCAGTAATTGAGAGTGCTGCTAAGATTAACAGCCAGTTCAAAAGAGAAATCACAATGAACCATAAATCTGTATGGAGTAAAGGAA
AGTTGAAACTGGCTGGGGTTTTTTTTTTTTTTTTTTTTTTTGAGGAGAAAGGTCAATTGAATCTTATTCGTATAATATGCACATCCATAG
ACAAGAATTATTTTGCATTAACTCTACAACTTAGTTGTAAAAATAGCTCAAAGGCAGTGAAAGACTAGAATCAGATAATTGGAAGGGTGC
ACCCTAAGCAATGCATAGTTCTATTTTCTTTCTTTTTTTTTTTGAGACAGAGTTTCCCTCTTGTCACACAGGCTGGAGCGCAGTGGTGCA
ATCTTGGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGACTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCATGCCAC
CACAACTGGCTAATTTTTGTATTTTTAGTAGATACAGGGTTTCACTGTGTTGGCCAGGTTGGTCTCATACTCCTGACCTCAGGTGATCCA
CCCGCCTCGGCCTCCCAAAATGTTGGGATTACAGGCGTCAGCCACCACGCCCGGCCCCAATGCATAGTTTTTTACTGAAGACAACCAGAA
TCTCTGTTGCTTATTCCAAATTTCCTTCCACCACTTGTCCATCCAGCAGAGCCACTTTTAAAATAGGACACAGGCAGAAATTTAAAGGAG
TCAATATCTCATGGTGAAAAGTGAATCCTGAGGGTTAGAGCATCCACCAGGTGCCCTAGGTAAGGGCCAGCCACTCTGGGAGGCAGCCCG
GGGCACTCACTGTCCTCTCAGTAGTAAATGAAATCACTCAGGCCATGTCTGCTACCCAGAGAGCCTGAGTGTCCTCAAATGCTTGTTCTG
CCTCTCCATCCACTCCTGCAGACACCTCAGTGGCTGCATCCCAAACCGCTGAACTTTGCTTCTCTTTCTCCAACCCCCAATTCCACCCAC
ATCCAAAACTGCTCTGCCCCCTATTCCCATCTCAGCTGAGGGTACTATCATCCACCCTGTGGCCACATCCAGGAATGTGTGTATCACCTG
GGCTCTGAGGATGACATCAGCTCTTCTAAGTCAACAGAATGTCGGGTCTGTTCTAAAAGTCTCATCTGACAAGGAGATCTTTAAGGCTTT
ACTCCCTTAAAGGCTTTACTCCCATCATGATGGGATAACCATCATGATGGATTTCAGTGTCATTCTGTCTTTTTCTTCGGAATGATTCCT
GGGACTCGCCTTGTTTGCAACATGTGCATTGAAATATCTTTTCAACATAACTTTGTTCTTAATTGTGTTTACTTCCTTTCTCTGTGAATC
TCAGTGATTCCTGGAAGCTGTGGTTGGTGGGGGATGGGGTGGGAGGACTTTGGTAGTATAAAAGAGTACCTGCAATGAATGTTCTAAGAA
ACTGGAGTGTTGGGGTCCTCCAGCCCTTGGCTGGTAAACTCTCCACTCCTTCCTCTTTGCAACACAATTCTCATAACTGGCAAAGGTGTG
CATGTAAAATTTGTGACTGTAGTCTGAGGTTTTTTTTCCCTGTACAATTCCGCCTTCCCCCCTGTAAGCCTGTACCAGGAGAGGTCTCAG
CTGCCTTGGAGGCGGTGAGACACGTGGGTGCTCACTGTGGCCCTCAAGGGTGAGGCTGGCACTGGGGCATCTGGGGCCAGAAGTCCTCCT
TTAGTCCCAAGTCTCTGCCACTCAAGTGCATCAGTGAGAGGTCCTCATAGAAAATCTACTGTGGGCACAAAGCTGCCAGGCTGATGGGGG
TGGGGAGCAAACGAACACCCTTTTCCCCTTTTACACCAGAGGAAAGAGACTTAGACTGAGGAACTTGCCTGCTGCCAGACAGCTGGGAGG
TGGTAGAACCGGGCTTACAGCCCAGGGTTTCCACTCTAGGAACTCTTCTCCCTTCCTCTGATGACACTAACTCGCAGGCCATGATCAATG
AGCAACGATGTAGGCAGGCACTGACGAGGCACAGCAGGAAGGCAGCTCAGTGCCCATGACGGCCAGGAACTGGGTACCATTTCCTCAGCA
AAATGGGATAGTAACTCCCACACTGCAGCTACGCACTTGGGCAGTGGTTCACAAGGCCAGCAGCCACAACATCACCCCAGACCAGCAGCA
GCTGCAGCATTACCCCCAGCACTTGTTAAAAGATGCAAATTCAGGCCAGGTGTGGTGGCTCGTGCCTGTAATCCCAGTACTTTGGGAAGC
CAAGGCGGGTGGGTCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAATGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATGA
CCCGGGCATGGTTGTGGGCGCCTGTAATCCCAGCTACCCAGGAGACCGAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGT
CAGCCGAGATTGTGCCATTACACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTTTCAATAAATAAATAAAAATGCAAATTGTATGCCCC
TTCCTTCAGGCCTATGGGACCAAAAACTGGGATGGGGCCCAATAAAATGTTTTAACCAGCCCTTCGGTGGTTACAGAAGGATAGAGCCAG
AATAGACTAACCACTGTAACAAACATTACCTATACTTGGGAGGCTTTGAAAAATGTTTATTTAGCCGGGTGCGGTGGCTCACGCCTGTAA
TCCCAACACTTTGGGAGGCTGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCAGCCTGGCTAACACAGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAGGTGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGTAGAATTTCTTGAACCCAG
GAGGCGGGGCTTGCAGTAAGTCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAGG
AAAGAAAAATGTTTATTTTTTTGCTCATGCCACAGTCTCTGGTAGTTGCTGGGAACTAGGGTGGGGGATTCTCTGCTCCACACAGTCTTT
CATGGACCCAGGTTCCTTTCCTGTTGTGGGTCCAGCCTCCTGTAGCTGTTGGAGGCATCTCTAGTCAGCTGGTGGTTGGGGAAGAGGTGA
GGATCAGGGAGGGAAGATGGAGAGTACTCTGCTTGTTCTCACATTCTGCTGGCCAGAACTCACAAGCCACCTGAAATGATGCAAAGGTCT
AGCTGTGTGTGTAGGAGAAAGAAGAGAGGCCAGATATTGGAAGACAGCAGTGGTCTGTGCCCCAGGCCCCATGGTTTAGGGAAGTGAACC
TTGGCACTGGATTTCCTGGCTTTCTAAATCTCCCTTTATAGGGAACTTAGGGCCCAGTCTGTGGTGGGTGGATTTGCCTGGTTCACAGCC
TCTGGTCAGCCTTCTTTCTGCTCCACAGGGCGGCCTGGAGATGGTGGGCTCCTTGTCACACTGGTTGGGGATGTGGGCTCCATGGGGCCA
GAGATGTGTGTGCTCTGTGTTCAGATTAAGGGACAGACGGCACATGAATTCCTTCAGTGCCCTCCAGATTTGGTCACTGGGGAGGGGTAG
GCTGAGCAGTAGCTCTTGGGTCTGTAGTAGTGTGACCCTGGAAGGACTGTCCAGCTGAAAACAAGAGCCTGGGGCGTGGGGAGGGGAGGG
GTTACTCAGGGTTCCATGAGACCTGGGTTTAAGTCCTGGATCCATCATTAGCAGCTATGTGAACTTATGCCTCACTTTCCTCAAATATGA
ACTTGAGATAATGAAATTACCTTCCTCATAATACTGTTCTAAGAATTGAATGAGGAAAGGTTTACAATTCGGCCCTGGTTGTTCCACTGG
GGAGGGAACAGAGATTGGGGGCACAGGGCTCCCCTGGCCTGGGGGAGTCTGGCTCACTCAAGTTCTCAGTCATTTGCAAGGCAAGGACCC
TGCTTCTCCTTGCTCTGGGTCCGAGTAGTCTCAAGCCCAGTGGGCAGGGCCTGTGGTGTGGATGGACTCGTCTGCAGTGAGTCAGGCAGC
AGGCAGAGCTGGCAGGCTGTGTGGTCTCTAGTGGGTACCAGGGGACCTGGGAGGGCCTTGTGGGAGGTTGTCCACGGTGTGAGCCAGTTT
GCCATCTGGGGTCCTGGAGTTCCCTCCCGCCCTTTGAGTTAAAAAGAGTCAGTCCTGGGCTGAGACTTAATTGCGCTAGTGCTGAGTGAC
CTTGTGTCAGGGGAAATCGGATGGGGCAAAGTGTTTTTTAATTAGCAGGACTCACTGACCTTTCCTTCACTGTCAGCAACTTCTCACAGG
GAGGCAGAGCAAGGGGGGCTGGAGCCCCGCATCTCTCTAATGGAGCCTATGTCCAACAAGGAGGTGGATGGCTGGATTCAGGGCCCTGGG
AGGACTTCATGTGGGAAGCAGACCTCAGGAAGGGCCCTTAGTGATGGTGTGGGCCAGGGTTCTCACCTCCTTAGTCTCCTGTCCTGTCCA
TCTCCGCAGATCCTAGGCAAAAGAAGCGGAGAAACACTCAAGCCACTGGGGTGGTTAGGGCACACTGGTGGCAACTGTTTAAAACCTTAA
CTAAAACAAGGTTAAGCAAAAGGAGTTTACAGGCTCTCATAGATGGGAAGGATGTGGGAGGGTCACAGACTGAGAGGAACCAGGGCTGTG
GCTGCTGGAAGGAGCCTCACCACCGCCAGTGTGTTTCCTCCCCGTCGTCGGCATCTCTGCTTCTCTCTGCACGCCAGCAGCTCTCTCTTA
GGGCACGCAGACCTTTCCTCTGCAGGGGAACACGAGTGCCGGCAGCCCCGAGTTAGTGACTATCATAGAAACTCAGTGTATTTCTCTCTT
GTTTATCATTCCGAGTCCTGAGTCACAGGCTTGTCCAGCACTCAAGACTTTTTCTTTTCTCTATTTTTTGAAACGGATTCTCGCTCTGTC
CCCCAGGCTGGAGTGCAGTGGCCCGATTTTGGGTGCAAGCGATTCTCCTGCCTCAACCTCCCGAGTAGCTGGGACTACAGGTGTGCGCCA
CCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAGGCTGGTTTCAAACTCCTGACCTCCCGCCGGCC
TCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGCCTGGCCAAGATTTTTTCTTTTAAACCTGGAGTATGGAGATGCTCAC
TAGGCAGACAGAATCAGCCACCACAGCCCACTCCCTCAGCCAGTATTACTTTGACTAAGTTAGTGAGGAACCAGGCCCCAGATTAAGAAG
CAGAACTCACACTGTCATCTGCTGTGTGCCTGGCTGGCTCATGCATACCTTGTCTATCTAATGTGGACCAAAGCCCTGTGGCACACCCTG
CTGGTTACCCCCAGTGGTTACCCTGGCACAGAGGAGGAAAGGGAGTCGTGGGAGGGAGAAGGACTTCCCTGGGAGGTCTCTGGGCTGGCA
AGTTGGGTGACACAGGTCCGGTTGGCTGCAAGCCTGGGCTCTGCTGTTGTAATCATAAATGTGTGTGTGTGTACAGTTGTTTACAATGTC
AGCATGGGTGTCCTTGTTTGTTAGAGATACATGCCACTGCTCCCATCATGAGGAAAATCCCAAGCCCTCCCCATGATTTTTGCCAGTTTC
TGGGGACTCATGCTCCTGGCAGCCCATGTGTCCCCAACTCCTGTGTCCTTTAGGGACCTCTGTTGAGCCCTGCCTCTATTCTGGCAGAAT
TAGAGAAAATTCTTTAAAAAAACAATAAAGTTTAAATTCATTTAAAAAAATAATAAAAAATCTCACAGCATGAGTTTTGATGAGATTTGG
GGCAAGGTGGGCCACAACCTTGGGTTGTATGGCCACCTCCCCCTCTTCTTCCCCTGTTGTCTCTGCAGCTCAGAAACCCCAATTTCCTGG
CCTGTGTTATGTGGAGGAGCTGAGCTCACCCCCTACAGCTTCATCTCCAAACCTAGCAAGGATCCTGCCCAGATCAGGAGATCCTCCTTT
TAACAGAAGTTATTTACACTCCTTAGAAAGCAGTGGGGGTGGAACGATTCTTTTTCCTGATGCAGAGATGTAAAACTGGGACATTGCTAC
ACATAATATTTTAAACCTGTCTTCCCTCTTACCAACGAACACATCACTAGCACCATCTATGCCAATACATTTCTCAACATCAATTTCAGT
GGCTGTATTACATTTTATCCTACGGATGTGCTCTCATTTATAATCTAAACCACTTTTATTGAACACATCAGTTATTCTGAAATTTTCAGT
GTTATGATGGATGTTGCAGTAATTATTCTTATATATGCACAGAACCCCCAGAGGACATGACTACTGAAGGCTGTGCTGGCAGGATCACAG
GTAAGGATCTAGCAAATTGTCCCAGCTTCATTGACTGAGCTTTCATCCTTGTTGCACTACTTTGAGCTGCCATTTTGATCATATAATAAT
GATTTAGTAGAGCTCTTTTTTGGTTCAACCTACCTGTTCTTGTATCAGAACTGAAATGTTTGATTTTATAAATTTGAATAGTGGCACAAT
ATAGAGTTCACTATTCCTCAATATTTTCAAGGCTGTTTCTTATCTGTTCATTCTTTTGGTTAACTTGGGAATTATTTTATCAAGTCTCTC
TACTTCCCAATTTCCTTTCACCTTTGGCTCGAAATGATATTCAATGTATACATTAACTTGAGTTACATTTTGCTGCATAATGCTTGAGTT
ACATTTTGAGTATTACGTGTTACTCATAATACATATTGAGTTACATTTTGCTGCATAATACATTATCCCCAAGTTTAACACCTTAAAGCA
GCACATATATATCTCATACCCTTCTGAGGGTCAGGAATCTAGAAGCAGCTTAGCTGGGTGACTGTGGCTCTGGGTCTCTCATGAGGCTGC
AGTGAAACTGTTGGCCAGGGCTGGAGGATCCCTTCCAACCTCACTCCATGACTGTTGGTGGGAGGCTTCAGTTCTCCACCTGGTTCTCAC
AATATAATTTCCCCCAGAGTGAGTTATCAGAGAGAGTGTGCAACCAGTAATCTGTTAGAATATGTCACGTCTGTCATATTTGATTGGTCA
CTCAGACCAACCCTAATAGATGCGAGAGTGACTATGCAAGGGTGTGAGTTCCAGGAGGAAAGCATCATTGGAACCATCTTGGAGACTGGC
TAATACACAGATAAATGGCACATCTGACAATATGGCATCTTTCTGAGTGTCAGTGTGGTGTGTTCCTATATGAACTTAATGCTATTAAAC
TTAATTAAATTGTAGGTATGCTCTCAGTGAAGATTTTTACTTTTACATTACAGGTTTCCACACTGTTAAATTCATTCCAAGTATTTCATA
CATGCTGTTCCTATTATGAAAGGATCTTTTTTTTCACATGGCATTTTCTAAGTAGTTGTTGCATTCATATAGGAGATGCTATTGATTTTG
ACACCCATAATTTTTCAGTGGAGACAAGGCAGAAACTACTCCAGACTCTCACCTGCTGTTGCTGATCCTTACATGGTGGCTGTGCCAGGC
TCAGCCGCGCTGAGATGACAGGGCTGTCTGGCCATCATTGGTCATATGGACTTCAGATTTGAAAGGATTTTATGTAGAAGCAGAGTGCCT
GATAGGACTCTCCGGGACCCCCATTTCTGCCCTGCTTGGCTCCCACTGGCAAGGCTGGCTCAGTTCCTGTCACCTTCTCCTGGACTTTGG
CCAGAGTCCACTGGCTGTTTCCCCTGCCTCCTGCTCTCCCAGTGCCCTCTCCACACCAGTGCCAGAGCTGCTTCTAAGAGATGCCTCAAA
GCCCGCTTCCAGCTTAGGAACCCCAGGGAACATGGATGGTTTCTCCATTGCCACTTCCTAGCCTTCCTGGCATAGGAAGGTCTGGTTTGC
CTGCAGGTCCCTCTCTGGGGGGGTCCCTGCTCCATAGATGCTGAGGCTCCAGAAGTCTGTTCTTTTATATCACATTTGAAAACCTTTGAA


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FusionGenePPI for MTMR10_TSPAN14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MTMR10SMAD9, SMAD5, MEOX2, MTMR2, MTMR10, MTM1, LONP2, TP53RK, NMNAT1, OSGEP, NUDT16, GADD45GIP1, IDE, AATK, ERBB3, PTK7TSPAN14ELAVL1, ATP13A2, ADAM10, PIK3CA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MTMR10_TSPAN14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MTMR10_TSPAN14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource