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Fusion gene ID: 22777 |
FusionGeneSummary for MTM1_VBP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MTM1_VBP1 | Fusion gene ID: 22777 | Hgene | Tgene | Gene symbol | MTM1 | VBP1 | Gene ID | 4534 | 7411 |
| Gene name | myotubularin 1 | VHL binding protein 1 | |
| Synonyms | CNM|MTMX|XLMTM | HIBBJ46|PFD3|PFDN3|VBP-1 | |
| Cytomap | Xq28 | Xq28 | |
| Type of gene | protein-coding | protein-coding | |
| Description | myotubularinphosphatidylinositol-3,5-bisphosphate 3-phosphatasephosphatidylinositol-3-phosphate phosphatase | prefoldin subunit 3von Hippel-Lindau binding protein 1 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q13496 | P61758 | |
| Ensembl transtripts involved in fusion gene | ENST00000370396, ENST00000542741, ENST00000543350, ENST00000306167, ENST00000413012, | ENST00000535916, ENST00000286428, ENST00000459836, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 4 X 4 X 4=64 |
| # samples | 3 | 4 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MTM1 [Title/Abstract] AND VBP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MTM1 | GO:0006470 | protein dephosphorylation | 9537414 |
| Hgene | MTM1 | GO:0008333 | endosome to lysosome transport | 14722070 |
| Hgene | MTM1 | GO:0044088 | regulation of vacuole organization | 14722070 |
| Hgene | MTM1 | GO:0046856 | phosphatidylinositol dephosphorylation | 10900271|12646134 |
| Hgene | MTM1 | GO:0070584 | mitochondrion morphogenesis | 21135508 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-55-6712-01A | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000370396 | ENST00000535916 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000370396 | ENST00000286428 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 5CDS-intron | ENST00000370396 | ENST00000459836 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000542741 | ENST00000535916 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000542741 | ENST00000286428 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 5CDS-intron | ENST00000542741 | ENST00000459836 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000543350 | ENST00000535916 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000543350 | ENST00000286428 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 5CDS-intron | ENST00000543350 | ENST00000459836 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 3UTR-3CDS | ENST00000306167 | ENST00000535916 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 3UTR-3CDS | ENST00000306167 | ENST00000286428 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 3UTR-intron | ENST00000306167 | ENST00000459836 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000413012 | ENST00000535916 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| In-frame | ENST00000413012 | ENST00000286428 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
| 5CDS-intron | ENST00000413012 | ENST00000459836 | MTM1 | chrX | 149787612 | + | VBP1 | chrX | 154448460 | + |
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FusionProtFeatures for MTM1_VBP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MTM1 | VBP1 |
| Lipid phosphatase which dephosphorylatesphosphatidylinositol 3-monophosphate (PI3P) andphosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also beenshown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation throughregulation of EGFR trafficking from the late endosome to thelysosome. Plays a role in vacuolar formation and morphology.Regulates desmin intermediate filament assembly and architecture.Plays a role in mitochondrial morphology and positioning. Requiredfor skeletal muscle maintenance but not for myogenesis.{ECO:0000269|PubMed:10900271, ECO:0000269|PubMed:11001925,ECO:0000269|PubMed:12646134, ECO:0000269|PubMed:14722070,ECO:0000269|PubMed:21135508, ECO:0000269|PubMed:9537414}. | Binds specifically to cytosolic chaperonin (c-CPN) andtransfers target proteins to it. Binds to nascent polypeptidechain and promotes folding in an environment in which there aremany competing pathways for nonnative proteins.{ECO:0000269|PubMed:9630229}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MTM1 | chrX:149787612 | chrX:154448460 | ENST00000370396 | + | 6 | 15 | 29_97 | 148 | 604 | Domain | Note=GRAM |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MTM1 | chrX:149787612 | chrX:154448460 | ENST00000370396 | + | 6 | 15 | 163_538 | 148 | 604 | Domain | Myotubularin phosphatase |
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FusionGeneSequence for MTM1_VBP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_315aa MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVI SRIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFM ELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATK >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_315aa MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVI SRIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFM ELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATK >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_220aa MGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLA QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSL >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_220aa MGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLA QKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSL >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_200aa MRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEIL KYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMAR >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_200aa MRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEIL KYMQKKKESTNSMETRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMAR >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_278aa MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYITNYRLYLRSLETDMRNLRFALKQEG HSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNS METRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKD >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_278aa MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYITNYRLYLRSLETDMRNLRFALKQEG HSRRDMFEILTRYAFPLAHSLEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNS METRFLLADNLYCKASVPPTDKMCLWLGANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_945nt ATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGAT CTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAG GGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATC TCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGAGGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGG TTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGAT GTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATG GAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAG AAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATG TGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAG AATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGAT >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_945nt ATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGAT CTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAG GGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATC TCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGAGGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGG TTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGAT GTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATG GAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAG AAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATG TGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAG AATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGAT >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_660nt ATGGGAGGCGCGACAAGTAGAGGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAG GAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATG AAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCT CAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACC AACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGG GCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTG GAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAAC >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_660nt ATGGGAGGCGCGACAAGTAGAGGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAG GAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATG AAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCT CAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACC AACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGG GCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTG GAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAAC >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_600nt ATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCT CACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAG AAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTA AAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCT CCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTA TCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGG >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_600nt ATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCT CACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAG AAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTA AAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCT CCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTA TCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGG >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_834nt ATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGAT CTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAG GGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGC CACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAG CCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAG AAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCA ATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAAT GTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAA GACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGAT >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_834nt ATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGAT CTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAG GGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGC CACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAG CCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAG AAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCA ATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAAT GTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAA GACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_1201nt GCAGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACAC TCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACA CTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAGGGAAGAGTTTACATCACAAATTATCGTCTTTATTTA AGAAGTTTGGAAACGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATCTCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGA GGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGAT ATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACT GCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAA GGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTC TTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATAT GATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTT CGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAAC AAAGCATAATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTT TGAATGTTTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACAT >In-frame_MTM1_ENST00000370396_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_1974nt GCAGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACAC TCCTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACA CTAATCACTGACAAAGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAGGGAAGAGTTTACATCACAAATTATCGTCTTTATTTA AGAAGTTTGGAAACGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATCTCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGA GGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGAT ATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACT GCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAA GGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTC TTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATAT GATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTT CGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAAC AAAGCATAATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTT TGAATGTTTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACAT TGTGATTTTTTTTTCCACATTTCTCAGCAAAGCTAATGGTATTTTAATCATTATTTTTGCCTGTCATAAGAAAACTCTTAGCTGAAATGG CCGAAAACTGTGAGACATGCTATGGAAGCTGAATGCCGGACGCTAGCACAGTTTACTTTTTCCCTTTCTAATCGGCTGATGTTACTCTCA CTTGATGTGGTTAAACCATTTTAGAGGTAGAGAAGACAGACAGTTTGAATATTTGTAAACTTGTTTTTCTTTGGTATATTTAGGACTTAG TGGTCCTCTGTTGCTATTGTCTTCTATAAGTGGAGTTTCATGACTTACTGCTTAACGAATAACTAACTACTATGATATTCTGGACATTTT AGGAAATGGTAATTTGCCTTGCTACACATTAAGAGGGCTATTAAGACTACATTTTTTCTAACCTCAGATAAGTGCAGTGTCTTTGCAATG CCAACATAAGGGAGATCTTGGCCAACGTGAAATAAAATTACTCATTCAAAACTCTGCCTAAGGTGATTTTGTAGTTCTTAACAGTTCTCC AGAGCATCTTGAACAGGAATATTAAGATAAATGTGAATCTGCAATGGCTGAAAAGAGTTGTGAGCTTTTTTATTCATGATAAAACCTTAT AGGAATAGTATAAAAAATCCCTGTGGAAAGCTACTAGTACATTGACCAGCGCTGGGTGATACAGATTCTGATAAAAACATAAATGTATTA >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_1104nt AGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTC CTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACT AATCACTGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATCTCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGAGGAGAAA ATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTG AGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATA CAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGA TTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGG CAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTG ATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATC AATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCAT AATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGT TTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACATTGTGATT >In-frame_MTM1_ENST00000542741_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_1877nt AGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTC CTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACT AATCACTGGATTCTTCTCTAATACTTGATGTTCCTCTGGGTGTGATCTCGAGAATTGAAAAAATGGGAGGCGCGACAAGTAGAGGAGAAA ATTCCTATGGTCTAGATATTACTTGTAAAGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTG AGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATA CAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGA TTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGG CAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTG ATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATC AATTTACTACCACAGAAGTCAATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCAT AATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGT TTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACATTGTGATT TTTTTTTCCACATTTCTCAGCAAAGCTAATGGTATTTTAATCATTATTTTTGCCTGTCATAAGAAAACTCTTAGCTGAAATGGCCGAAAA CTGTGAGACATGCTATGGAAGCTGAATGCCGGACGCTAGCACAGTTTACTTTTTCCCTTTCTAATCGGCTGATGTTACTCTCACTTGATG TGGTTAAACCATTTTAGAGGTAGAGAAGACAGACAGTTTGAATATTTGTAAACTTGTTTTTCTTTGGTATATTTAGGACTTAGTGGTCCT CTGTTGCTATTGTCTTCTATAAGTGGAGTTTCATGACTTACTGCTTAACGAATAACTAACTACTATGATATTCTGGACATTTTAGGAAAT GGTAATTTGCCTTGCTACACATTAAGAGGGCTATTAAGACTACATTTTTTCTAACCTCAGATAAGTGCAGTGTCTTTGCAATGCCAACAT AAGGGAGATCTTGGCCAACGTGAAATAAAATTACTCATTCAAAACTCTGCCTAAGGTGATTTTGTAGTTCTTAACAGTTCTCCAGAGCAT CTTGAACAGGAATATTAAGATAAATGTGAATCTGCAATGGCTGAAAAGAGTTGTGAGCTTTTTTATTCATGATAAAACCTTATAGGAATA GTATAAAAAATCCCTGTGGAAAGCTACTAGTACATTGACCAGCGCTGGGTGATACAGATTCTGATAAAAACATAAATGTATTAGTTCATC >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_993nt AGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTC CTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACT AATCACTGGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGT TTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATG AACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTT TGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAG CTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGG AAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCA ATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCATAATGCTGGCAATTAAAAATGT GGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGTTTTAACAGCAAGAATTTTAAG AAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACATTGTGATTTTTTTTTCCACATTTCTCAGC >In-frame_MTM1_ENST00000543350_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_1766nt AGCCGAGCAGCCTGGCAACGGCGGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTC CTTGGAGAATGAGTCTATTAAGAGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACT AATCACTGGACATGAGAAACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGT TTCCCCTGGCTCACAGTCTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATG AACAGTACCAGAAGTATAAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTT TGGAAATTCTAAAATACATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAG CTTCAGTTCCTCCTACCGATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGG AAAAGAATTTATCGACTGCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCA ATATGGCCAGGGTTTATAATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCATAATGCTGGCAATTAAAAATGT GGTTTAGTTTTCCAAACATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGTTTTAACAGCAAGAATTTTAAG AAAAGATAAACACCATTTTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACATTGTGATTTTTTTTTCCACATTTCTCAGC AAAGCTAATGGTATTTTAATCATTATTTTTGCCTGTCATAAGAAAACTCTTAGCTGAAATGGCCGAAAACTGTGAGACATGCTATGGAAG CTGAATGCCGGACGCTAGCACAGTTTACTTTTTCCCTTTCTAATCGGCTGATGTTACTCTCACTTGATGTGGTTAAACCATTTTAGAGGT AGAGAAGACAGACAGTTTGAATATTTGTAAACTTGTTTTTCTTTGGTATATTTAGGACTTAGTGGTCCTCTGTTGCTATTGTCTTCTATA AGTGGAGTTTCATGACTTACTGCTTAACGAATAACTAACTACTATGATATTCTGGACATTTTAGGAAATGGTAATTTGCCTTGCTACACA TTAAGAGGGCTATTAAGACTACATTTTTTCTAACCTCAGATAAGTGCAGTGTCTTTGCAATGCCAACATAAGGGAGATCTTGGCCAACGT GAAATAAAATTACTCATTCAAAACTCTGCCTAAGGTGATTTTGTAGTTCTTAACAGTTCTCCAGAGCATCTTGAACAGGAATATTAAGAT AAATGTGAATCTGCAATGGCTGAAAAGAGTTGTGAGCTTTTTTATTCATGATAAAACCTTATAGGAATAGTATAAAAAATCCCTGTGGAA AGCTACTAGTACATTGACCAGCGCTGGGTGATACAGATTCTGATAAAAACATAAATGTATTAGTTCATCTCCATGTAGTAAAAAGTATAC >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000535916_chrX_154448460_+_1066nt GGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAG AGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATT TACATATGTCCTTTCAATGGCCCCATTAAGGGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGACATGAGA AACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGT CTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTAT AAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATAC ATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACC GATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACT GCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTAT AATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCATAATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAAC ATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGTTTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATT >In-frame_MTM1_ENST00000413012_chrX_149787612_+_VBP1_ENST00000286428_chrX_154448460_+_1839nt GGTGGCGCCCGGAGCCCGAGAGTTTCCAGGATGGCTTCTGCATCAACTTCTAAATATAATTCACACTCCTTGGAGAATGAGTCTATTAAG AGGACGTCTCGAGATGGAGTCAATCGAGATCTCACTGAGGCTGTTCCTCGACTTCCAGGAGAAACACTAATCACTGACAAAGAAGTTATT TACATATGTCCTTTCAATGGCCCCATTAAGGGAAGAGTTTACATCACAAATTATCGTCTTTATTTAAGAAGTTTGGAAACGGACATGAGA AACCTGAGGTTCGCTTTGAAACAGGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTCACGAGATACGCGTTTCCCCTGGCTCACAGT CTGGAAGATGTAGATTCCTTCATGAAACAGCCTGGGAATGAGACTGCAGATACAGTATTAAAGAAGCTGGATGAACAGTACCAGAAGTAT AAGTTTATGGAACTCAACCTTGCTCAAAAGAAAAGAAGGCTAAAAGGTCAGATTCCTGAAATTAAACAGACTTTGGAAATTCTAAAATAC ATGCAGAAGAAAAAAGAGTCCACCAACTCAATGGAGACCAGATTCTTGCTGGCAGATAACCTGTATTGCAAAGCTTCAGTTCCTCCTACC GATAAAATGTGTCTGTGGTTGGGGGCTAATGTAATGCTTGAATATGATATTGATGAAGCTCAGGCATTGTTGGAAAAGAATTTATCGACT GCCACAAAGAATCTTGATTCCCTGGAGGAAGACCTTGACTTTCTTCGAGATCAATTTACTACCACAGAAGTCAATATGGCCAGGGTTTAT AATTGGGATGTAAAAAGAAGAAACAAGGATGACTCTACCAAGAACAAAGCATAATGCTGGCAATTAAAAATGTGGTTTAGTTTTCCAAAC ATGTTATCTTAAATACCCCTTTATCCTTACAGGTTGACATAACTTTGAATGTTTTAACAGCAAGAATTTTAAGAAAAGATAAACACCATT TTATTTATTTATAAAAACAAAATTAGTTTCAAATATTTTTGACATTGTGATTTTTTTTTCCACATTTCTCAGCAAAGCTAATGGTATTTT AATCATTATTTTTGCCTGTCATAAGAAAACTCTTAGCTGAAATGGCCGAAAACTGTGAGACATGCTATGGAAGCTGAATGCCGGACGCTA GCACAGTTTACTTTTTCCCTTTCTAATCGGCTGATGTTACTCTCACTTGATGTGGTTAAACCATTTTAGAGGTAGAGAAGACAGACAGTT TGAATATTTGTAAACTTGTTTTTCTTTGGTATATTTAGGACTTAGTGGTCCTCTGTTGCTATTGTCTTCTATAAGTGGAGTTTCATGACT TACTGCTTAACGAATAACTAACTACTATGATATTCTGGACATTTTAGGAAATGGTAATTTGCCTTGCTACACATTAAGAGGGCTATTAAG ACTACATTTTTTCTAACCTCAGATAAGTGCAGTGTCTTTGCAATGCCAACATAAGGGAGATCTTGGCCAACGTGAAATAAAATTACTCAT TCAAAACTCTGCCTAAGGTGATTTTGTAGTTCTTAACAGTTCTCCAGAGCATCTTGAACAGGAATATTAAGATAAATGTGAATCTGCAAT GGCTGAAAAGAGTTGTGAGCTTTTTTATTCATGATAAAACCTTATAGGAATAGTATAAAAAATCCCTGTGGAAAGCTACTAGTACATTGA CCAGCGCTGGGTGATACAGATTCTGATAAAAACATAAATGTATTAGTTCATCTCCATGTAGTAAAAAGTATACTTATACAATGTTTTGTA |
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FusionGenePPI for MTM1_VBP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MTM1 | KBTBD7, KMT2A, BIN1, CUL4A, HLA-C, KIAA1468, KRT2, KRT5, SNX17, MTMR11, MTM1, MTFR1, SAMM50, CALU, CIAO1, STIP1, RCN1, SNX6, VBP1, TARBP2, CCT8L1P, AKR7A2, NDUFA9, OXA1L, SOAT1, STOML2, IMMT, ILK, SCO2, MTMR10, TRIML2, TUBA3C | VBP1 | VHL, PFDN2, MSH4, PAN2, PRPF4, PPP2CB, TUBA3E, XRCC6, PIK3R3, FBXW8, MKNK2, PFDN4, PFDN5, PFDN6, KARS, EPRS, GARS, NUBP2, NAB2, IARS, DARS, CLNS1A, QARS, TRMT1, PSMC2, METTL21B, HDAC1, VCP, MAPK7, SSB, TNPO1, UBQLN2, ANP32A, ARPC1B, ARPC4, PPP3CA, RABGGTA, TTLL12, FKBP6, PNMA1, UBL7, DCAF5, PEX7, CBS, FLNA, TXNDC12, DCUN1D1, FLNB, GOLPH3, PFDN1, RNASEH2B, SEC24B, XPNPEP1, BTRC, EWSR1, POC1A, POC1B, ANAPC15, PTPN21, DUSP16, DUSP8, DUSP9, MTM1, PHKB, COPRS, CCDC101, SUPT6H, PDRG1, STK26, GSPT1, GNB2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MTM1_VBP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MTM1_VBP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MTM1 | C0410203 | X-linked centronuclear myopathy | 13 | CTD_human;ORPHANET;UNIPROT |
| Hgene | MTM1 | C0752282 | Congenital Structural Myopathy | 1 | CTD_human |
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