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Fusion gene ID: 22751 |
FusionGeneSummary for MTFR1_LIG1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MTFR1_LIG1 | Fusion gene ID: 22751 | Hgene | Tgene | Gene symbol | MTFR1 | LIG1 | Gene ID | 9650 | 26018 |
| Gene name | mitochondrial fission regulator 1 | leucine rich repeats and immunoglobulin like domains 1 | |
| Synonyms | CHPPR|FAM54A2 | LIG-1|LIG1 | |
| Cytomap | 8q13.1 | 3p14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mitochondrial fission regulator 1chondrocyte protein with a poly-proline region | leucine-rich repeats and immunoglobulin-like domains protein 1leucine-rich repeat protein LRIG1ortholog of mouse integral membrane glycoprotein LIG-1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q15390 | P18858 | |
| Ensembl transtripts involved in fusion gene | ENST00000262146, ENST00000517944, ENST00000458689, | ENST00000263274, ENST00000536218, ENST00000427526, ENST00000599165, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 6 X 6 X 4=144 |
| # samples | 2 | 6 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MTFR1 [Title/Abstract] AND LIG1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-X6-A8C2-01A | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000262146 | ENST00000263274 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| In-frame | ENST00000262146 | ENST00000536218 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| In-frame | ENST00000262146 | ENST00000427526 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 5CDS-intron | ENST00000262146 | ENST00000599165 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 3UTR-3CDS | ENST00000517944 | ENST00000263274 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 3UTR-3CDS | ENST00000517944 | ENST00000536218 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 3UTR-3CDS | ENST00000517944 | ENST00000427526 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 3UTR-intron | ENST00000517944 | ENST00000599165 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| In-frame | ENST00000458689 | ENST00000263274 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| In-frame | ENST00000458689 | ENST00000536218 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| In-frame | ENST00000458689 | ENST00000427526 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
| 5CDS-intron | ENST00000458689 | ENST00000599165 | MTFR1 | chr8 | 66605994 | + | LIG1 | chr19 | 48647220 | - |
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FusionProtFeatures for MTFR1_LIG1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MTFR1 | LIG1 |
| May play a role in mitochondrial aerobic respiration.May also regulate mitochondrial organization and fission (Bysimilarity). {ECO:0000250}. | DNA ligase that seals nicks in double-stranded DNAduring DNA replication, DNA recombination and DNA repair. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000262146 | + | 4 | 8 | 137_169 | 93 | 334 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000458689 | + | 2 | 6 | 137_169 | 60 | 301 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000262146 | + | 4 | 8 | 184_197 | 93 | 334 | Compositional bias | Note=Pro-rich |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000458689 | + | 2 | 6 | 184_197 | 60 | 301 | Compositional bias | Note=Pro-rich |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000262146 | + | 4 | 8 | 179_304 | 93 | 334 | Region | Necessary and sufficient to promote mitochondrial fission |
| Hgene | >MTFR1 | chr8:66605994 | chr19:48647220 | ENST00000458689 | + | 2 | 6 | 179_304 | 60 | 301 | Region | Necessary and sufficient to promote mitochondrial fission |
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FusionGeneSequence for MTFR1_LIG1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_755aa MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECS ARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGL ELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACR HSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGL ERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTS FILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIE QIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICK LGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPE >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_755aa MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECS ARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGL ELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACR HSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGL ERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTS FILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIE QIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICK LGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPE >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_755aa MLGWIKRLIRMVFQQVGVSMQSVLWSRKPYGSSRSIVRKIGTNLSLIQCPRVQFQINSHATEWSPSHPGEDAVASFADVGWVAKEEGECS ARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGL ELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACR HSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGL ERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTS FILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIE QIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICK LGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPE >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_722aa MLGWIKRLIRMVFQQVGVSMQSINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVP YLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGD VGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVS LTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRF EEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDA SEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKR SHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDG AVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDT >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_722aa MLGWIKRLIRMVFQQVGVSMQSINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVP YLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGD VGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVS LTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRF EEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDA SEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKR SHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDG AVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDT >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_722aa MLGWIKRLIRMVFQQVGVSMQSINSHATEWSPSHPGEDAVASFADVGWVAKEEGECSARLRPLDPSGYNPAKNNYHPVEDACWKPGQKVP YLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGD VGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVS LTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRF EEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDA SEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKR SHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDG AVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_2265nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGGTACTTTGGTCTAGGAAGCCATAT GGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAGTGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCA ACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCA GCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAG AAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTG CTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTG GAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAG AAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTC AGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGC CACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAG GCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGG CTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTG GAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTG AAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAG ATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCC TTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAG GTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTT TCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAG CAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATC GCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTAC CTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAG CTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGG ATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTAC CCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAG CAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCT >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_2265nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGGTACTTTGGTCTAGGAAGCCATAT GGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAGTGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCA ACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCA GCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAG AAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTG CTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTG GAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAG AAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTC AGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGC CACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAG GCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGG CTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTG GAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTG AAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAG ATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCC TTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAG GTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTT TCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAG CAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATC GCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTAC CTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAG CTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGG ATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTAC CCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAG CAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCT >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_2265nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGGTACTTTGGTCTAGGAAGCCATAT GGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAGTGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCA ACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCA GCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAG AAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTG CTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTG GAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAG AAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTC AGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGC CACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAG GCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGG CTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTG GAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTG AAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAG ATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCC TTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAG GTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTT TCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAG CAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATC GCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTAC CTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAG CTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGG ATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTAC CCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAG CAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCT >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_2166nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGG AGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTA AGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCT TACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCC GTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGC GTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGAC GTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTC CGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAA GCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGC CTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAG CAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTC CCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTT GAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGC AGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTG GACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCG TCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGC CGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCC GAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGA TCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGG GGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACT GGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGC GCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCG CGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACC ACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACC >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_2166nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGG AGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTA AGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCT TACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCC GTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGC GTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGAC GTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTC CGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAA GCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGC CTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAG CAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTC CCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTT GAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGC AGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTG GACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCG TCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGC CGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCC GAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGA TCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGG GGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACT GGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGC GCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCG CGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACC ACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACC >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_2166nt ATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGG AGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTA AGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCT TACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCC GTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGC GTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGAC GTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTC CGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAA GCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGC CTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAG CAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTC CCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTT GAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGC AGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTG GACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCG TCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGC CGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCC GAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGA TCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGG GGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACT GGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGC GCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCG CGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACC ACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_2595nt AGAAGCCTGAGGAGCCGGAGAGGGTGCTGGCTGCCGCGCGGCCGAGTGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTA CTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTA AGCATGCAATCGGTACTTTGGTCTAGGAAGCCATATGGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAG TGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCAACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGAT GTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTAT CATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCT GCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTC AGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGT CGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATG CTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAG ATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGG CTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCT GGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTG GACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATG TTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGG GCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGC CGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAG CCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATC TACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTT GTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATG GTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTG GGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTAC GACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAG GCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAG GTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCT CGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATT CAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCCTCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTT GGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAGGCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTG >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_2590nt AGAAGCCTGAGGAGCCGGAGAGGGTGCTGGCTGCCGCGCGGCCGAGTGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTA CTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTA AGCATGCAATCGGTACTTTGGTCTAGGAAGCCATATGGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAG TGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCAACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGAT GTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTAT CATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCT GCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTC AGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGT CGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATG CTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAG ATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGG CTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCT GGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTG GACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATG TTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGG GCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGC CGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAG CCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATC TACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTT GTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATG GTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTG GGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTAC GACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAG GCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAG GTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCT CGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATT CAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCCTCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTT GGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAGGCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTG >In-frame_MTFR1_ENST00000262146_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_2590nt AGAAGCCTGAGGAGCCGGAGAGGGTGCTGGCTGCCGCGCGGCCGAGTGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTA CTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTA AGCATGCAATCGGTACTTTGGTCTAGGAAGCCATATGGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAG TGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCAACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGAT GTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGGATCCATCTGGTTACAATCCTGCCAAGAACAACTAT CATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTGTGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCT GCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCCTGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTC AGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATGGTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGT CGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGGTGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATG CTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCGCCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAG ATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCATCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGG CTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCCCGGGCCAAGAATTCCCACCAGCCATGGTGGATGCT GGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGATCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTG GACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACTGCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATG TTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAGCTTTCACCTGCGAATACAAATATGACGGGCAGAGG GCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGGAAGACAACACTGGGAAGTACCCGGACATCATCAGC CGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAGCCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAG CCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCCAGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATC TACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGCTCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTT GTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGGAGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATG GTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACTGGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTG GGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGGCCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTAC GACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTGATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAG GCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTCCCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAG GTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGGTGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCT CGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTCAGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATT CAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCCTCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTT GGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAGGCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTG >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000263274_chr19_48647220_-_2450nt TGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTACTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCT GGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGGAGTCCCAGCC ACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGG ATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTG TGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCC TGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATG GTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGG TGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCG CCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCA TCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCC CGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGA TCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACT GCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAG CTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGG AAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAG CCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCC AGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGC TCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGG AGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACT GGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGG CCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTG ATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTC CCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGG TGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTC AGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCC TCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTTGGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAG GCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTGTGTGAGGGGGTGGCTTACTCCGGAGTCTGGGATTCATCCCGTCATTTCTTTCAAT >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000536218_chr19_48647220_-_2445nt TGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTACTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCT GGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGGAGTCCCAGCC ACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGG ATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTG TGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCC TGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATG GTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGG TGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCG CCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCA TCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCC CGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGA TCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACT GCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAG CTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGG AAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAG CCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCC AGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGC TCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGG AGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACT GGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGG CCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTG ATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTC CCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGG TGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTC AGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCC TCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTTGGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAG GCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTGTGTGAGGGGGTGGCTTACTCCGGAGTCTGGGATTCATCCCGTCATTTCTTTCAAT >In-frame_MTFR1_ENST00000458689_chr8_66605994_+_LIG1_ENST00000427526_chr19_48647220_-_2445nt TGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTACTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCT GGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGATTAACAGCCATGCAACAGAATGGAGTCCCAGCC ACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGACCCCTGG ATCCATCTGGTTACAATCCTGCCAAGAACAACTATCATCCCGTGGAAGATGCCTGCTGGAAACCGGGCCAGAAGGTTCCTTACCTGGCTG TGGCCCGGACGTTTGAGAAGATCGAGGAGGTGTCTGCTCGGCTCCGGATGGTGGAGACGCTGAGCAACTTGCTGCGCTCCGTGGTGGCCC TGTCGCCTCCAGACCTCCTCCCTGTCCTCTACCTCAGCCTCAACCACCTTGGGCCACCCCAGCAGGGCCTGGAGCTTGGCGTGGGTGATG GTGTCCTTCTCAAGGCAGTGGCCCAGGCCACAGGTCGGCAGCTGGAGTCCGTCCGGGCTGAGGCAGCCGAGAAAGGCGACGTGGGGCTGG TGGCCGAGAACAGCCGCAGCACCCAGAGGCTCATGCTGCCACCACCTCCGCTCACTGCCTCCGGGGTCTTCAGCAAGTTCCGCGACATCG CCAGGCTCACTGGCAGTGCTTCCACAGCCAAGAAGATAGACATCATCAAAGGCCTCTTTGTGGCCTGCCGCCACTCAGAAGCCCGGTTCA TCGCTAGGTCCCTGAGCGGACGGCTGCGCCTTGGGCTGGCAGAGCAGTCGGTGCTGGCTGCCCTCTCCCAGGCAGTGAGCCTCACGCCCC CGGGCCAAGAATTCCCACCAGCCATGGTGGATGCTGGGAAGGGCAAGACAGCAGAGGCCAGAAAGACGTGGCTGGAGGAGCAAGGCATGA TCCTGAAGCAGACGTTCTGCGAGGTTCCCGACCTGGACCGAATTATCCCCGTGCTGCTGGAGCACGGCCTGGAACGTCTCCCGGAGCACT GCAAGCTGAGCCCAGGGATTCCCCTGAAACCAATGTTGGCCCATCCCACCCGGGGCATCAGCGAGGTCCTGAAACGCTTTGAGGAGGCAG CTTTCACCTGCGAATACAAATATGACGGGCAGAGGGCACAGATCCACGCCCTGGAAGGCGGGGAGGTGAAGATCTTCAGCAGGAATCAGG AAGACAACACTGGGAAGTACCCGGACATCATCAGCCGCATCCCCAAGATTAAACTCCCATCGGTCACATCCTTCATCCTGGACACCGAAG CCGTGGCTTGGGACCGGGAAAAGAAGCAGATCCAGCCATTCCAAGTGCTCACCACCCGCAAACGCAAGGAGGTGGATGCGTCTGAGATCC AGGTGCAGGTGTGTTTGTACGCCTTCGACCTCATCTACCTCAATGGAGAGTCCCTGGTACGTGAGCCCCTTTCCCGGCGCCGGCAGCTGC TCCGGGAGAACTTTGTGGAGACAGAGGGCGAGTTTGTCTTCGCCACCTCCCTGGACACCAAGGACATCGAGCAGATCGCCGAGTTCCTGG AGCAGTCAGTGAAAGACTCCTGCGAGGGGCTGATGGTGAAGACCCTGGATGTTGATGCCACCTACGAGATCGCCAAGAGATCGCACAACT GGCTCAAGCTGAAGAAGGACTACCTTGATGGCGTGGGTGACACCCTGGACCTGGTGGTGATCGGCGCCTACCTGGGCCGGGGGAAGCGGG CCGGCCGGTACGGGGGCTTCCTGCTGGCCTCCTACGACGAGGACAGTGAGGAGCTGCAGGCCATATGCAAGCTTGGAACTGGCTTCAGTG ATGAGGAGCTGGAGGAGCATCACCAGAGCCTCAAGGCGCTGGTGCTGCCCAGCCCACGCCCTTACGTGCGGATAGATGGCGCTGTGATTC CCGACCACTGGCTGGACCCCAGCGCTGTGTGGGAGGTGAAGTGCGCTGACCTCTCCCTCTCTCCCATCTACCCTGCTGCGCGGGGCCTGG TGGATAGTGACAAGGGCATCTCCCTTCGCTTCCCTCGGTTTATTCGAGTCCGTGAAGACAAGCAGCCGGAGCAGGCCACCACCAGTGCTC AGGTGGCCTGTTTGTACCGGAAGCAAAGTCAGATTCAGAACCAACAAGGCGAGGACTCAGGCTCTGACCCTGAAGATACCTACTAAGCCC TCGCCCTCCTAGGGCCTGGGTACAGGGCATGAGTTGGACGGACCCCAGGGTTATTATTGCCTTTGCTTTTTAGCAAATCTGCTGTGGCAG GCTGTGGATTTTGAGAGTCAGGGGAGGGGTGTGTGTGTGAGGGGGTGGCTTACTCCGGAGTCTGGGATTCATCCCGTCATTTCTTTCAAT |
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FusionGenePPI for MTFR1_LIG1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MTFR1 | DUSP23, DICER1, ENO1, SHMT2, MOV10, NXF1, COLEC11, CENPO, CBWD1, CCDC151, FGL2, CAPZA2, MTM1, DIABLO, IL13RA2, CTAGE5, ATG14, CCDC120, P2RX5 | LIG1 | PCNA, MRE11A, RGS2, PRMT3, MOV10, RNF166, HSPB1, CHTF18, FEN1, POLA1, SKIV2L2, STKLD1, NTRK1, AURKA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | LIG1 | chr8:66605994 | chr19:48647220 | ENST00000263274 | - | 8 | 28 | 449_458 | 258 | 920 | target DNA |
| Tgene | LIG1 | chr8:66605994 | chr19:48647220 | ENST00000263274 | - | 8 | 28 | 642_644 | 258 | 920 | target DNA |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MTFR1_LIG1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | LIG1 | P18858 | DB00290 | Bleomycin | DNA ligase 1 | small molecule | approved|investigational |
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RelatedDiseases for MTFR1_LIG1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LIG1 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
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