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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 22389

FusionGeneSummary for MPPE1_PIEZO2

check button Fusion gene summary
Fusion gene informationFusion gene name: MPPE1_PIEZO2
Fusion gene ID: 22389
HgeneTgene
Gene symbol

MPPE1

PIEZO2

Gene ID

65258

63895

Gene namemetallophosphoesterase 1piezo type mechanosensitive ion channel component 2
SynonymsPGAP5C18orf30|C18orf58|DA3|DA5|DAIPT|FAM38B|FAM38B2|HsT748|HsT771|MWKS
Cytomap

18p11.21

18p11.22-p11.21

Type of geneprotein-codingprotein-coding
Descriptionmetallophosphoesterase 1metallo phosphoesterasepost-GPI attachment to proteins factor 5piezo-type mechanosensitive ion channel component 2PIEZO2 variant 16family with sequence similarity 38, member A pseudogenefamily with sequence similarity 38, member B2piezo-type mechanosensitive ion channel component 1 pseudogeneprotein PIEZO2
Modification date2018052320180523
UniProtAcc

Q53F39

Q9H5I5

Ensembl transtripts involved in fusion geneENST00000588072, ENST00000317235, 
ENST00000309976, ENST00000344987, 
ENST00000592755, ENST00000399978, 
ENST00000302079, ENST00000580640, 
ENST00000503781, ENST00000383408, 
ENST00000538948, ENST00000285141, 
ENST00000581680, 
Fusion gene scores* DoF score2 X 2 X 2=83 X 3 X 2=18
# samples 23
** MAII scorelog2(2/8*10)=1.32192809488736log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MPPE1 [Title/Abstract] AND PIEZO2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-C8-A26V-01AMPPE1chr18

11889386

-PIEZO2chr18

10871413

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000588072ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000588072ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000588072ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000588072ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000588072ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000588072ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000588072ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000317235ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000317235ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000317235ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000317235ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000317235ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000317235ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000317235ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
Frame-shiftENST00000309976ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
Frame-shiftENST00000309976ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
Frame-shiftENST00000309976ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000309976ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000309976ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000309976ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000309976ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000344987ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000344987ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000344987ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000344987ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000344987ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000344987ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000344987ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-3CDSENST00000592755ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-3CDSENST00000592755ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-3CDSENST00000592755ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-intronENST00000592755ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-intronENST00000592755ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-intronENST00000592755ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
intron-intronENST00000592755ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000399978ENST00000302079MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000399978ENST00000580640MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
In-frameENST00000399978ENST00000503781MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000399978ENST00000383408MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000399978ENST00000538948MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000399978ENST00000285141MPPE1chr18

11889386

-PIEZO2chr18

10871413

-
5CDS-intronENST00000399978ENST00000581680MPPE1chr18

11889386

-PIEZO2chr18

10871413

-

Top

FusionProtFeatures for MPPE1_PIEZO2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MPPE1

Q53F39

PIEZO2

Q9H5I5

Component of a mechanosensitive channel required forrapidly adapting mechanically activated (MA) currents. Requiredfor Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation. {ECO:0000250|UniProtKB:Q8CD54}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMPPE1chr18:11889386chr18:10871413ENST00000309976-4827_47164334TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000317235-5927_47164334TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000399978-51127_47164342TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000588072-51127_47164397TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131458_1529-149545Coiled coilOntology_term=ECO:0000255
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511458_15291092690Coiled coilOntology_term=ECO:0000255
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521458_15291092753Coiled coilOntology_term=ECO:0000255
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141458_1529-47710Coiled coilOntology_term=ECO:0000255
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541458_15291092778Coiled coilOntology_term=ECO:0000255
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132099_2135-149545Compositional biasNote=Ser-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013453_480-149545Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013609_668-149545Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013852_901-149545Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512099_21351092690Compositional biasNote=Ser-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351453_4801092690Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351609_6681092690Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351852_9011092690Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522099_21351092753Compositional biasNote=Ser-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352453_4801092753Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352609_6681092753Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352852_9011092753Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142099_2135-47710Compositional biasNote=Ser-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014453_480-47710Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014609_668-47710Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014852_901-47710Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542099_21351092778Compositional biasNote=Ser-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354453_4801092778Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354609_6681092778Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354852_9011092778Compositional biasNote=Glu-rich
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131053_1073-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131134_1154-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131170_1190-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013119_139-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131217_1237-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131291_1311-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131315_1335-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131349_1371-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131404_1424-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131900_1920-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131935_1955-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0131967_1987-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013214_234-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132191_2211-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132232_2252-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132260_2280-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132290_2310-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132327_2344-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132358_2378-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013237_257-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132406_2426-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0132662_2682-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013266_286-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-01327_47-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013336_356-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013505_525-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013541_561-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013581_598-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-0135_25-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-01362_82-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013678_698-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013704_724-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013732_752-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013782_802-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013932_952-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013958_978-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000285141-013985_1005-149545TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511053_10731092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511134_11541092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511170_11901092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351119_1391092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511217_12371092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511291_13111092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511315_13351092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511349_13711092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511404_14241092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511900_19201092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511935_19551092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3511967_19871092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351214_2341092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512191_22111092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512232_22521092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512260_22801092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512290_23101092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512327_23441092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512358_23781092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351237_2571092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512406_24261092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3512662_26821092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351266_2861092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351336_3561092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351505_5251092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351541_5611092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351581_5981092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351678_6981092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351704_7241092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351732_7521092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351782_8021092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351932_9521092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351958_9781092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-351985_10051092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521053_10731092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521134_11541092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521170_11901092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352119_1391092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521217_12371092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521291_13111092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521315_13351092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521349_13711092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521404_14241092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521900_19201092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521935_19551092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3521967_19871092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352214_2341092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522191_22111092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522232_22521092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522260_22801092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522290_23101092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522327_23441092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522358_23781092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352237_2571092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522406_24261092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3522662_26821092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352266_2861092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352336_3561092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352505_5251092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352541_5611092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352581_5981092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352678_6981092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352704_7241092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352732_7521092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352782_8021092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352932_9521092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352958_9781092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-352985_10051092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141053_1073-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141134_1154-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141170_1190-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014119_139-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141217_1237-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141291_1311-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141315_1335-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141349_1371-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141404_1424-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141900_1920-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141935_1955-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0141967_1987-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014214_234-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142191_2211-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142232_2252-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142260_2280-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142290_2310-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142327_2344-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142358_2378-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014237_257-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142406_2426-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0142662_2682-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014266_286-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-01427_47-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014336_356-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014505_525-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014541_561-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014581_598-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-0145_25-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-01462_82-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014678_698-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014704_724-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014732_752-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014782_802-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014932_952-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014958_978-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000538948-014985_1005-47710TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541053_10731092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541134_11541092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541170_11901092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354119_1391092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541217_12371092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541291_13111092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541315_13351092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541349_13711092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541404_14241092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541900_19201092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541935_19551092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3541967_19871092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354214_2341092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542191_22111092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542232_22521092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542260_22801092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542290_23101092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542327_23441092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542358_23781092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354237_2571092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542406_24261092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3542662_26821092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354266_2861092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354336_3561092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354505_5251092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354541_5611092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354581_5981092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354678_6981092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354704_7241092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354732_7521092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354782_8021092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354932_9521092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354958_9781092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-354985_10051092778TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMPPE1chr18:11889386chr18:10871413ENST00000309976-48392_396164334MotifNote=Di-lysine motif
HgeneMPPE1chr18:11889386chr18:10871413ENST00000317235-59392_396164334MotifNote=Di-lysine motif
HgeneMPPE1chr18:11889386chr18:10871413ENST00000399978-511392_396164342MotifNote=Di-lysine motif
HgeneMPPE1chr18:11889386chr18:10871413ENST00000588072-511392_396164397MotifNote=Di-lysine motif
HgeneMPPE1chr18:11889386chr18:10871413ENST00000309976-48356_376164334TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000317235-59356_376164334TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000399978-511356_376164342TransmembraneHelical
HgeneMPPE1chr18:11889386chr18:10871413ENST00000588072-511356_376164397TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-35127_471092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-3515_251092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000302079-35162_821092690TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-35227_471092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-3525_251092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000503781-35262_821092753TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-35427_471092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-3545_251092778TransmembraneHelical
TgenePIEZO2chr18:11889386chr18:10871413ENST00000580640-35462_821092778TransmembraneHelical


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FusionGeneSequence for MPPE1_PIEZO2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_2745aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSF
SVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIIL
SRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRIL

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_2833aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYSHAKVNGRVYLIINS
IKKKLPIHQNELAHPEGSLPDLTMMHLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWH
LVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLY
QLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPV
SRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQ
YFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASF
SQHNPVPDFIHCRSYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMK
NILSIGACGYIGTLVHNSCWLIQAFSLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASR
GAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWV
DHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEP
IKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGL
DTIDEHPGAASGAQTAHRMDSLDSHDSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLT
PEEELTQFSTLDGDVEAPPSYSKAVSFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKF
YVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWN
KNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASV
ESVHVTFPEQQTAVRRKRSGSSSEPSQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVP
IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKV
IFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAV
MDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVS
VTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSV
VFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSR
DNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKL

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_2808aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMD
QQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSF
PLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNS
QALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIF

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_2745aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSF
SVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIIL
SRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRIL

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_2833aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYSHAKVNGRVYLIINS
IKKKLPIHQNELAHPEGSLPDLTMMHLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWH
LVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLY
QLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPV
SRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQ
YFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASF
SQHNPVPDFIHCRSYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMK
NILSIGACGYIGTLVHNSCWLIQAFSLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASR
GAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWV
DHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEP
IKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGL
DTIDEHPGAASGAQTAHRMDSLDSHDSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLT
PEEELTQFSTLDGDVEAPPSYSKAVSFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKF
YVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWN
KNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASV
ESVHVTFPEQQTAVRRKRSGSSSEPSQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVP
IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKV
IFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAV
MDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVS
VTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSV
VFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSR
DNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKL

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_2808aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMD
QQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSF
PLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNS
QALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIF

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_2745aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSF
SVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIIL
SRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRIL

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_2833aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYSHAKVNGRVYLIINS
IKKKLPIHQNELAHPEGSLPDLTMMHLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWH
LVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLY
QLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPV
SRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQ
YFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASF
SQHNPVPDFIHCRSYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMK
NILSIGACGYIGTLVHNSCWLIQAFSLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASR
GAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWV
DHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEP
IKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGL
DTIDEHPGAASGAQTAHRMDSLDSHDSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLT
PEEELTQFSTLDGDVEAPPSYSKAVSFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKF
YVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWN
KNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASV
ESVHVTFPEQQTAVRRKRSGSSSEPSQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVP
IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKV
IFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAV
MDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVS
VTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSV
VFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSR
DNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKL

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_2808aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMD
QQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSF
PLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNS
QALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIF

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_2745aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSF
SVVFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIIL
SRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRIL

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_2833aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYSHAKVNGRVYLIINS
IKKKLPIHQNELAHPEGSLPDLTMMHLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWH
LVIDRLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLY
QLQTIKPENFSVNCSLPNENQTNIPFNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPV
SRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQ
YFICIGIPPAPCRDYPWRFKGASFNDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASF
SQHNPVPDFIHCRSYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMK
NILSIGACGYIGTLVHNSCWLIQAFSLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASR
GAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWV
DHASMVRSGDYYLFETDSEEEEEEELKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEP
IKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGL
DTIDEHPGAASGAQTAHRMDSLDSHDSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLT
PEEELTQFSTLDGDVEAPPSYSKAVSFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKF
YVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWN
KNVEVNKDKPYHPPNIIGVEKKEGYVLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASV
ESVHVTFPEQQTAVRRKRSGSSSEPSQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVP
IKQFFYNLIHPEYSAVTDVYVLMFLADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKV
IFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAV
MDWVWTDTTLSLSSWICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVS
VTITLGGYQPIFTMSAQQSQLKVMDQQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSV
VFSWSIQRNLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSR
DNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKL

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_2808aa
MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLD
KLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYDLKGADAGNGIRVFVP
DIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFENEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFI
GNMITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLAIFTAGHLIGLYLYQFQFFQEAVPPNDYYA
RLFGIKSVIQTDCSSTWKIIVNPDLSWYHHANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYATHYP
TDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQYRWEPSDESSEKREEEEEEKEEFEEERSREEKRSIK
VHAMVSVFQFIMKQSYICALIAMMAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELPEIKKVPGFL
EKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQENEEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEE
EDEQDIMKVLGNLVVAMFIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSVVIYTMLVLIFIYTYQ
FENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFLLVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMM
HLTASLEKPEVRKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVIDRLTVLFLKFLEYFHKLQVFMW
WILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFALPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIP
FNELNKSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTAPVSRTIFHDITRLHLDDGLINCAKYFI
NYFFYKFGLETCFLMSVNVIGQRMDFYAMIHACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASFN
DNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEICMNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFS
YLFWFVLTIIFITGTTRISIFCMGYLVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNVFVITMKNILSIGACGYIGTLVHNSCWLIQAF
SLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLHVVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMD
QLKRQMDRIKARQQKYKKGKERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYYLFETDSEEEEEEE
LKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERKRRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVL
FLATVDSFTTWLNSISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEHPGAASGAQTAHRMDSLDSH
DSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAPEPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAV
SFEHLSFGSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKFYVGQPRFLLLFYAMYNTLVARSEMV
CYFVIILNHMVSASMITLLLPILIFLWAMLSVPRPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGY
VLYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSINLAASVESVHVTFPEQQTAVRRKRSGSSSEP
SQRSSFSSNRSQRGSTSTRNSSQKGSSVLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVYVLMFL
ADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDRALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERK
FSQNLVAQLWYFVKCVYFGLSAYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSSWICVEDIYAHI
FILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLFMSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKVMD
QQSFNKFIQAFSRDTGAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQRNLSLGAKSEIATDKLSF
PLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSDSNSKPIKQLLSENNFMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNS
QALELVVFNDKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCTDIFLVRETGELELEEDLYAKLIF


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_8235nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGC
TTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAA
CTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTC
TCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAA
AATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCA
TATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTG
TCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTG
GAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTC
CTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTG
AAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGC

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8499nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGC
ATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGC
CTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGG
AAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCAC
CTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTG
CACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCT
TTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTAC
CAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAAC
AAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAAC
CTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTG
TCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTAC
AAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTG
ATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAG
TATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAG
TGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGG
CAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTC
AGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTT
GTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTT
GGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAA
AATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACA
GTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCC
TTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGA
GGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAG
ATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGAC
ATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTT
GATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGAT
GAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAG
AAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCA
ATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTG
GACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGA
GAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTG
GACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGC
GAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGG
AGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACC
CCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTG
TCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATC
TTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTC
TACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATC
ATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCC
AGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAAT
AAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTC
ATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCC
AGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTG
GAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGC
TTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGC
AAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCC
ATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGAC
TTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCG
GGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTC
ATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTG
GTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGG
AACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTG
ATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGT
TGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTC
CTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCC
GTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAAC
AAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAA
GGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTT
GTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATT
ACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTAT
GTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGA
GACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTG
GTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTG
ATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTG
TGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCA

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8424nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGA
GGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAG
CCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGAC
CAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACA
GTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAAT
AGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTT
CCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAG
ATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACC
ATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCT
CAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCT
TCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGAT
CGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTC

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_8235nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGC
TTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAA
CTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTC
TCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAA
AATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCA
TATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTG
TCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTG
GAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTC
CTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTG
AAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGC

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8499nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGC
ATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGC
CTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGG
AAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCAC
CTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTG
CACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCT
TTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTAC
CAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAAC
AAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAAC
CTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTG
TCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTAC
AAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTG
ATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAG
TATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAG
TGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGG
CAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTC
AGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTT
GTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTT
GGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAA
AATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACA
GTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCC
TTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGA
GGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAG
ATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGAC
ATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTT
GATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGAT
GAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAG
AAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCA
ATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTG
GACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGA
GAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTG
GACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGC
GAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGG
AGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACC
CCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTG
TCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATC
TTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTC
TACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATC
ATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCC
AGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAAT
AAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTC
ATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCC
AGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTG
GAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGC
TTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGC
AAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCC
ATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGAC
TTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCG
GGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTC
ATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTG
GTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGG
AACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTG
ATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGT
TGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTC
CTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCC
GTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAAC
AAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAA
GGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTT
GTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATT
ACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTAT
GTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGA
GACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTG
GTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTG
ATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTG
TGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCA

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8424nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGA
GGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAG
CCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGAC
CAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACA
GTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAAT
AGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTT
CCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAG
ATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACC
ATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCT
CAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCT
TCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGAT
CGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTC

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_8235nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGC
TTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAA
CTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTC
TCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAA
AATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCA
TATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTG
TCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTG
GAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTC
CTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTG
AAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGC

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8499nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGC
ATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGC
CTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGG
AAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCAC
CTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTG
CACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCT
TTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTAC
CAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAAC
AAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAAC
CTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTG
TCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTAC
AAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTG
ATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAG
TATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAG
TGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGG
CAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTC
AGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTT
GTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTT
GGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAA
AATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACA
GTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCC
TTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGA
GGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAG
ATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGAC
ATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTT
GATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGAT
GAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAG
AAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCA
ATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTG
GACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGA
GAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTG
GACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGC
GAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGG
AGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACC
CCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTG
TCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATC
TTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTC
TACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATC
ATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCC
AGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAAT
AAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTC
ATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCC
AGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTG
GAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGC
TTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGC
AAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCC
ATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGAC
TTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCG
GGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTC
ATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTG
GTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGG
AACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTG
ATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGT
TGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTC
CTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCC
GTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAAC
AAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAA
GGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTT
GTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATT
ACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTAT
GTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGA
GACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTG
GTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTG
ATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTG
TGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCA

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8424nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGA
GGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAG
CCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGAC
CAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACA
GTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAAT
AGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTT
CCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAG
ATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACC
ATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCT
CAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCT
TCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGAT
CGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTC

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_8235nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGC
TTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAA
CTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTC
TCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAA
AATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCA
TATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTG
TCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTG
GAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTC
CTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTG
AAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGC

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8499nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGC
ATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGC
CTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGG
AAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCAC
CTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTG
CACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCT
TTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTAC
CAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAAC
AAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAAC
CTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTG
TCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTAC
AAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTG
ATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAG
TATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAG
TGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGG
CAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTC
AGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTT
GTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTT
GGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAA
AATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACA
GTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCC
TTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGA
GGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAG
ATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGAC
ATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTT
GATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGAT
GAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAG
AAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCA
ATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTG
GACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGA
GAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTG
GACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGC
GAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGG
AGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACC
CCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTG
TCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATC
TTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTC
TACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATC
ATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCC
AGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAAT
AAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTC
ATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCC
AGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTG
GAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGC
TTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGC
AAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCC
ATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGAC
TTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCG
GGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTC
ATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTG
GTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGG
AACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTG
ATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGT
TGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTC
CTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCC
GTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAAC
AAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAA
GGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTT
GTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATT
ACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTAT
GTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGA
GACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTG
GTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTG
ATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTG
TGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCA

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8424nt
ATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTC
TTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGAT
GGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGAC
AAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATC
TTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAG
CTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCT
GACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGT
AACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGA
GATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATT
GGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTG
TATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTG
GCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCA
AGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCAC
GCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGG
ACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCC
ACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGAT
TACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCT
GATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAA
GTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTAT
CACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCC
TTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTA
GAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAA
GCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAA
GTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAA
GAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTC
TTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCAC
TATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAG
TTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCT
GAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTC
ACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATG
CATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAG
AAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTA
AGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGG
TGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTT
TTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTC
TGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCC
TTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTC
TACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAAC
CTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATT
AATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATC
CACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGC
ATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAAT
GACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGT
GCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTT
GATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGC
TACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTC
TACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTT
GTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTC
AGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGAC
AGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAG
ATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGAC
CAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCA
GGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGG
TGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAA
TTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGA
CAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGAC
CGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTA
TTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGA
TGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCC
AGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACAT
GACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAG
GAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAG
GAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTG
AGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAG
CTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAA
GAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTG
TGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTG
TCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGG
TTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTAT
GTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACT
GAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAAC
CTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCA
TCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGT
ATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTG
GAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTG
GCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCA
GAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACT
GTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAA
TTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCA
ACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACT
GAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATA
TTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGA
GGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAG
CCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGAC
CAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACA
GTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAAT
AGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTT
CCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAG
ATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACC
ATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCT
CAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCT
TCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGAT
CGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_10743nt
AAGCAAGTGCATAATAAATATTATAGTTATCCTGATTGTCTCCTTTATTCATCACACACTTCCTAAGCACATCTCTGGAGGGCACTTTCC
AAGGCTCCGGGGGAGGAGAGGAAAGAGGCGCAGCCAGGCCTGGTGGGTCCCGGAGGGGCAGCGCGGCGCGGGAGGGGAACGGGGAGGCAC
GGCCTGGCTGCCACCGCGCGCGGAACCCGGGAGCGGCTCCGGGGCTGTCAGCTGCCCGCCTGGCTCCTCCAAGGCCTGGAGCTCGGACGC
GGGCTCTGGGGGCTTCTGGGGCGCGGAAGCGGGCTCGCGGGGAGCAGTGGCCGCCCCCGGCCGCCGCGGTGGCTGTGCTCAGAAGCCGGC
CCTGGCGTCAGGAGGCCGGGCGCGCGGCGCGGGGCGCGAGTTCCCCTGCCCGCCTGTGCGCCCCGCAACGGGCCTTTCCTGGGCCCTAAC
GACAGCTCGCCCGTGCTTCGCCCTCGCAGCTCTCCTGTGTCCCCAAAATGCCTTTCCCGCGTCCCCCGCCCTTCAGCGGTGACTGCCCAG
GGGACTCTGTAACGCGACACTCAGACTGCCGAGCCTGCCAGGCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGG
TTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGCGGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCG
CCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTGGGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTC
CCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAGGCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCT
CCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTG
GCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTC
TCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGG
CTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTT
TCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTA
CTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCAT
GTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCA
GACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGC
GGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCA
TTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCT
CCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGA
AAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTT
AAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTAC
CATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTC
CTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTT
ATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTG
TTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCT
GGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCAT
CCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGA
CTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGG
CCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGA
GAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAA
ACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTG
CACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACA
GTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCT
TTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAA
AATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGC
GAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCT
GGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAA
AATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGAT
GTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGG
ACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCT
GCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACAC
CATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAA
GTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGA
GGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGT
GCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTC
TTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCT
GCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGA
GAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCC
TATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGC
CTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACAT
TACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTT
CCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAG
AAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCC
ACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCAT
TGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAA
GGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGA
TTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCAC
TGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACC
CATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATG
TGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGC
TGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGT
TTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCAC
AATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCA
ACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGA
TGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAG
TGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGC
ATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGA
ACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACC
AGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAA
CTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCC
AACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGG
AGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCT
GTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGA
GGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTT
CTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTC
TGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCT
GACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCT
GCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGC
CTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGC
CATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGA
TAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTT
TCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCT
CTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCC
GGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAG
AGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAA
GCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCT
CATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTT
TTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCT
CATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTT
CGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGT
GAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAA
TTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACAC
AACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTAT
TTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGG
TGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCC
ACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAG
TCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGG
CAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACC
TATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTG
GGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAG
TCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGG
GATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGG
AGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAGAGAAAAAAC
AAATTGAAACCTTAGAACACAGACTGCAAATAATGTTAACATTTGAATTTTTTTTAAAAGCACAATATTCTCATAAGAGCTAAGCATTTC
TAGTTCGACGGAAATGGTTTGTTTCTCTTCTGATAGGTAGACAAAAGGAGCTGATATCCTTCTGCAGTAAAAGCTACCTTGCAAGTTAAG
GCACTGTTGAAAATGTTATTTGTAACTCCATTTCTCTGAAATCAGGGCTACTTGCTTTATGTTTTAGTCAACAGTGTCTCGCATTCTGAT
TGATCATGTGAAGGAATCATTTATGGGCCCCGTCCCTAAGAGAAACAGAAGAGGAGTCAGAAAGAAAGATGCCTGTGTTTTCCTCTGTGG
GGCCCGTGCACTTCCTGGAGAGATGCTACAATGCAATATACAGCGCTCCATCCCCACTGGGGAAGCTGCTGTGATGAGACTAGATGAGCC
TTCAACACACTCAGAAAATGCAACAGCAATAGGGGGCAGACAGCTCCTACCTGTGTTTCTAGGAGCAAAAGAGAGGGAACTAATTGCCCG
TGAAGACGCCAGTGGAAGGATCAGCCTCATTCTAAGCAAAAACATAGTATTAGTGATACTCTTACTGCCTTATCTTAACCAAGGACTAAT
AGGATACCTTTCCATTAAACACCAGTGACTTCTCAGGAAAAAAAAAAAAAAGGAGCAAAACAAATGATGTGTACACCTGCTTTGTTATGG
TCCACCAGTGACCAGCTTCAATGAGGGGAACCATTCTGGAGGGCTGCGGTCTCCTGTGCAAACAGACATGAGGCAGAAGAGTAAAAAGAC
CAACCCAGTGGGACCTAGAATACTTTGTAACTCTTTAATAACTGAGGTCAGGACCGCTCTTCTGCCTTCCCCTTCCCTTAACGTGCTTTT
TCCCATTTCCATGATTTAAGGCAATGGTTTTTCCAGTATGTGACATTTTCCTTCCTGTTTTTCAGGTATATCAAAGAGTTTACATATTCC
AATTCACATTTTTACATCTGAGACGGGTTTTTTAAGTTCATAATTATGAAAGAAATATGTATATTGAGCTTGGGGAAATAAAAATGGCCT
TTTCTTAAATTATTATTATTGGTAATACAACCTCTTCATTAAATAACAATGTAGCATGAAAAATTTATGATTGAAATGTAGTTTTCATTC
CATATTAAGATACAGTTTCTGAGAAGAATCATTGAATGGACTAGAATATGTCAAAAATTGATCCTGTGTAGTTTGGGTTCAGGGCTGACT

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_9721nt
AAGCAAGTGCATAATAAATATTATAGTTATCCTGATTGTCTCCTTTATTCATCACACACTTCCTAAGCACATCTCTGGAGGGCACTTTCC
AAGGCTCCGGGGGAGGAGAGGAAAGAGGCGCAGCCAGGCCTGGTGGGTCCCGGAGGGGCAGCGCGGCGCGGGAGGGGAACGGGGAGGCAC
GGCCTGGCTGCCACCGCGCGCGGAACCCGGGAGCGGCTCCGGGGCTGTCAGCTGCCCGCCTGGCTCCTCCAAGGCCTGGAGCTCGGACGC
GGGCTCTGGGGGCTTCTGGGGCGCGGAAGCGGGCTCGCGGGGAGCAGTGGCCGCCCCCGGCCGCCGCGGTGGCTGTGCTCAGAAGCCGGC
CCTGGCGTCAGGAGGCCGGGCGCGCGGCGCGGGGCGCGAGTTCCCCTGCCCGCCTGTGCGCCCCGCAACGGGCCTTTCCTGGGCCCTAAC
GACAGCTCGCCCGTGCTTCGCCCTCGCAGCTCTCCTGTGTCCCCAAAATGCCTTTCCCGCGTCCCCCGCCCTTCAGCGGTGACTGCCCAG
GGGACTCTGTAACGCGACACTCAGACTGCCGAGCCTGCCAGGCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGG
TTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGCGGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCG
CCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTGGGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTC
CCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAGGCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCT
CCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTG
GCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTC
TCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGG
CTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTT
TCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTA
CTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCAT
GTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCA
GACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGC
GGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCA
TTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCT
CCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGA
AAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTT
AAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTAC
CATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTC
CTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTT
ATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTG
TTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCT
GGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCAT
CCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGA
CTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGG
CCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGA
GAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAA
ACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTG
CACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACA
GTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCT
TTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAA
AATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGC
GAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCT
GGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAA
AATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGAT
GTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGG
ACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCT
GCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACAC
CATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGCATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGC
CCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGG
GGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGA
GGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATT
CCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGT
TTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTC
AAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAA
CTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGA
GTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCAT
TTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCT
AGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAA
CGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGC
AGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCG
AGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCC
TGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAAT
CATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAG
ATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGAT
CAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCT
GCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAAC
ATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTG
TACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTA
TTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGT
AAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAA
GGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGC
AGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTT
GTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTA
TCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCG
GAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAA
GAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGA
GCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCAT
CCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGC
ACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGG
GACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGA
GGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGG
GGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCG
TATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCT
GCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGC
CATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCT
CCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGA
GGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCC
CCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTT
GAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGG
CAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGC
TGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCAC
CCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTT
AATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTA
TAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAA
ACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAAC
CATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTG
GATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTT
CGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTT
CTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTC
CAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGG
CCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCAT
GTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCAC
AATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTAT
GCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAG
TAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGG
TGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAG
CACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAA
GCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCT
CAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGG
GTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTC
TCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACT
GGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAGAGAAAAAACAAATTG

>In-frame_MPPE1_ENST00000588072_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_9646nt
AAGCAAGTGCATAATAAATATTATAGTTATCCTGATTGTCTCCTTTATTCATCACACACTTCCTAAGCACATCTCTGGAGGGCACTTTCC
AAGGCTCCGGGGGAGGAGAGGAAAGAGGCGCAGCCAGGCCTGGTGGGTCCCGGAGGGGCAGCGCGGCGCGGGAGGGGAACGGGGAGGCAC
GGCCTGGCTGCCACCGCGCGCGGAACCCGGGAGCGGCTCCGGGGCTGTCAGCTGCCCGCCTGGCTCCTCCAAGGCCTGGAGCTCGGACGC
GGGCTCTGGGGGCTTCTGGGGCGCGGAAGCGGGCTCGCGGGGAGCAGTGGCCGCCCCCGGCCGCCGCGGTGGCTGTGCTCAGAAGCCGGC
CCTGGCGTCAGGAGGCCGGGCGCGCGGCGCGGGGCGCGAGTTCCCCTGCCCGCCTGTGCGCCCCGCAACGGGCCTTTCCTGGGCCCTAAC
GACAGCTCGCCCGTGCTTCGCCCTCGCAGCTCTCCTGTGTCCCCAAAATGCCTTTCCCGCGTCCCCCGCCCTTCAGCGGTGACTGCCCAG
GGGACTCTGTAACGCGACACTCAGACTGCCGAGCCTGCCAGGCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGG
TTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGCGGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCG
CCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTGGGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTC
CCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAGGCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCT
CCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTG
GCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTC
TCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGG
CTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTT
TCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTA
CTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCAT
GTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCA
GACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGC
GGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCA
TTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCT
CCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGA
AAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTT
AAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTAC
CATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTC
CTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTT
ATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTG
TTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCT
GGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCAT
CCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGA
CTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGG
CCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGA
GAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAA
ACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTG
CACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACA
GTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCT
TTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAA
AATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGC
GAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCT
GGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAA
AATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGAT
GTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGG
ACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCT
GCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACAC
CATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAA
GTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGA
GGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGT
GCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTC
TTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCT
GCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGA
GAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCC
TATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGC
CTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACAT
TACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTT
CCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAG
AAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCC
ACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCAT
TGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAA
GGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGA
TTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCAC
TGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACC
CATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATG
TGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGC
TGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGT
TTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCAC
AATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCA
ACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGA
TGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAG
TGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGC
ATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGA
ACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACC
AGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAA
CTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCC
AACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGG
AGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCT
GTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGA
GGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTT
CTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTC
TGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCT
GACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCT
GCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGC
CTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGC
CATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGA
TAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTT
TCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCT
CTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCC
GGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAG
AGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAA
GCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCT
CATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTT
TTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCT
CATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTT
CGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGT
GAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAA
TTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACAC
AACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATA
CCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTT
TCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTA
TCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAG
GGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGAC
CATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAG
AAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAAT
GATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAA
CTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAG
TGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAG
TCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATT
CTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCG
AGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAG

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_9869nt
GGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGC
ACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATG
CCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGA
CCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATC
GAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTT
CTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACC
ACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGG
GAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGG
AAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTT
GCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATG
TTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTT
GAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAA
GGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATC
ACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTA
TTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACT
GCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGT
ATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATC
CTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAG
GACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGA
AAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATC
CACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCA
GAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATG
GTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTG
ACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTT
TATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAG
CCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAA
AAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAG
CCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAG
GACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGC
TTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGG
AGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTC
CCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACT
CGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAG
TCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCC
AGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTT
GGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGG
CACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAG
TTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGG
GCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTG
TACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTG
AACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAAT
AACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCT
GTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTT
TACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGG
CTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTC
CAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATA
AAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAA
CGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCC
TTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGG
TTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTC
TTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATG
AAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGC
ACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTT
GCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCA
AGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGA
CAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAG
GACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGG
GTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAA
GATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAA
GAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAA
CCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACA
GTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACC
AGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGA
CTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCC
AGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCA
GGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTC
ACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCAT
CTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGC
ATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAA
TTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTG
ATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGG
CCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGG
AATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGAC
CTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATG
GCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCT
GTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCC
AGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAA
GGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTG
CCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTG
GACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTC
CCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAG
GTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAAC
CTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTG
GGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCA
GTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAG
TGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTT
ATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAAC
TCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTT
TCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGA
AAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAA
GCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAAT
ACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTC
TTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGG
AAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACA
GATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACA
ATGATCAAATGGACTAGAGAAAAAACAAATTGAAACCTTAGAACACAGACTGCAAATAATGTTAACATTTGAATTTTTTTTAAAAGCACA
ATATTCTCATAAGAGCTAAGCATTTCTAGTTCGACGGAAATGGTTTGTTTCTCTTCTGATAGGTAGACAAAAGGAGCTGATATCCTTCTG
CAGTAAAAGCTACCTTGCAAGTTAAGGCACTGTTGAAAATGTTATTTGTAACTCCATTTCTCTGAAATCAGGGCTACTTGCTTTATGTTT
TAGTCAACAGTGTCTCGCATTCTGATTGATCATGTGAAGGAATCATTTATGGGCCCCGTCCCTAAGAGAAACAGAAGAGGAGTCAGAAAG
AAAGATGCCTGTGTTTTCCTCTGTGGGGCCCGTGCACTTCCTGGAGAGATGCTACAATGCAATATACAGCGCTCCATCCCCACTGGGGAA
GCTGCTGTGATGAGACTAGATGAGCCTTCAACACACTCAGAAAATGCAACAGCAATAGGGGGCAGACAGCTCCTACCTGTGTTTCTAGGA
GCAAAAGAGAGGGAACTAATTGCCCGTGAAGACGCCAGTGGAAGGATCAGCCTCATTCTAAGCAAAAACATAGTATTAGTGATACTCTTA
CTGCCTTATCTTAACCAAGGACTAATAGGATACCTTTCCATTAAACACCAGTGACTTCTCAGGAAAAAAAAAAAAAAGGAGCAAAACAAA
TGATGTGTACACCTGCTTTGTTATGGTCCACCAGTGACCAGCTTCAATGAGGGGAACCATTCTGGAGGGCTGCGGTCTCCTGTGCAAACA
GACATGAGGCAGAAGAGTAAAAAGACCAACCCAGTGGGACCTAGAATACTTTGTAACTCTTTAATAACTGAGGTCAGGACCGCTCTTCTG
CCTTCCCCTTCCCTTAACGTGCTTTTTCCCATTTCCATGATTTAAGGCAATGGTTTTTCCAGTATGTGACATTTTCCTTCCTGTTTTTCA
GGTATATCAAAGAGTTTACATATTCCAATTCACATTTTTACATCTGAGACGGGTTTTTTAAGTTCATAATTATGAAAGAAATATGTATAT
TGAGCTTGGGGAAATAAAAATGGCCTTTTCTTAAATTATTATTATTGGTAATACAACCTCTTCATTAAATAACAATGTAGCATGAAAAAT
TTATGATTGAAATGTAGTTTTCATTCCATATTAAGATACAGTTTCTGAGAAGAATCATTGAATGGACTAGAATATGTCAAAAATTGATCC

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8847nt
GGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGC
ACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATG
CCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGA
CCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATC
GAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTT
CTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACC
ACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGG
GAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGG
AAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTT
GCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATG
TTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTT
GAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAA
GGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATC
ACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTA
TTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACT
GCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGT
ATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATC
CTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAG
GACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGA
AAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATC
CACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCA
GAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATG
GTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTG
ACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTT
TATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAG
CCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAA
AAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAG
CCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAG
GACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGC
TTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGG
AGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTC
CCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACT
CGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAG
TCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGCATCAAGAAAAAA
TTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCG
GAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAG
GAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGAC
CGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAA
ATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCG
TACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACC
ATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTC
TACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTG
GCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATC
TTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTG
GAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTA
TATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGC
ATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTC
CCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAG
GATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAAC
CCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATC
ATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTG
CTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCA
ATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTAT
CAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTG
CAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTT
TTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATC
AAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTC
TCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCC
ATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCA
CGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCT
GCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAA
TCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACT
ACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAG
GGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGAC
GAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAG
TGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCT
GAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAG
CTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCG
CAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTG
ACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAG
CCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCAC
ATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTC
TGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAG
GTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTG
GCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCA
GATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCAT
GTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAAC
AGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTT
TATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTC
TTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATT
GTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTG
GTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTC
ATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTT
TGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACC
AAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTG
TGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCG
GAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGC
ATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACC
CTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAA
GCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAAT
TCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGG
AGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAAT
ATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCT
AGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACT
AAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAAT
GACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTT
GTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATT
TTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATC

>In-frame_MPPE1_ENST00000317235_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8772nt
GGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGC
ACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATG
CCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGA
CCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATC
GAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTT
CTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACC
ACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGG
GAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGG
AAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTT
GCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATG
TTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTT
GAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAA
GGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATC
ACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTA
TTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACT
GCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGT
ATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATC
CTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAG
GACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGA
AAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATC
CACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCA
GAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATG
GTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTG
ACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTT
TATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAG
CCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAA
AAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAG
CCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAG
GACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGC
TTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGG
AGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTC
CCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACT
CGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAG
TCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCC
AGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTT
GGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGG
CACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAG
TTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGG
GCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTG
TACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTG
AACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAAT
AACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCT
GTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTT
TACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGG
CTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTC
CAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATA
AAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAA
CGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCC
TTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGG
TTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTC
TTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATG
AAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGC
ACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTT
GCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCA
AGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGA
CAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAG
GACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGG
GTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAA
GATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAA
GAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAA
CCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACA
GTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACC
AGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGA
CTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCC
AGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCA
GGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTC
ACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCAT
CTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGC
ATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAA
TTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTG
ATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGG
CCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGG
AATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGAC
CTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATG
GCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCT
GTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCC
AGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAA
GGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTG
CCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTG
GACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTC
CCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAG
GTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAAC
CTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTG
GGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCA
GTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAG
TGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATC
GTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTC
TCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTT
AACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTG
GAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCT
GTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAAT
ATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATAT
TATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCC
AGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAA
CTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTT
GTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAG
TTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCA

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_9850nt
GCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCAT
CTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTAC
CAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTC
CCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGAC
AGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAA
TCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCA
AAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAG
CGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGG
CCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTG
GCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCA
TCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTG
AAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCA
CGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCG
TTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCT
GGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGAC
TTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAA
CGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACT
ACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTA
GCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCC
AGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGG
AGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAG
AGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTA
TTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCT
GGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGA
TATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCA
AAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGG
AAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAG
AGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGG
GCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAA
TGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATT
TTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATA
TGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCT
CCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAG
ACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGG
TGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGT
CAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCC
TCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCG
TTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACG
CCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTA
AGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACA
GCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTA
TCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTC
ATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGA
CCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATA
GACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTG
GCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAG
ATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATG
AGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTG
TGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCT
TCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGT
TGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAG
GAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAA
TGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAA
GAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCC
AGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGG
CCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTG
AAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGG
TCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAA
GGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAA
GAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCG
ATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTT
GGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCA
ATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGC
ATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTA
CCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGC
CCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGA
CACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGG
ACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCC
ATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCC
GATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGG
TCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGA
TGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGA
ACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTC
TGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATG
ATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGA
CCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGAT
CCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATA
TGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTT
ACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCT
TCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGA
TGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTC
TTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGT
ACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGA
GCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGA
CGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGA
AGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGG
ACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCA
TCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAA
ACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGA
TAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACT
CAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTG
AGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTC
CCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCT
TCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAG
AGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAGAG
AAAAAACAAATTGAAACCTTAGAACACAGACTGCAAATAATGTTAACATTTGAATTTTTTTTAAAAGCACAATATTCTCATAAGAGCTAA
GCATTTCTAGTTCGACGGAAATGGTTTGTTTCTCTTCTGATAGGTAGACAAAAGGAGCTGATATCCTTCTGCAGTAAAAGCTACCTTGCA
AGTTAAGGCACTGTTGAAAATGTTATTTGTAACTCCATTTCTCTGAAATCAGGGCTACTTGCTTTATGTTTTAGTCAACAGTGTCTCGCA
TTCTGATTGATCATGTGAAGGAATCATTTATGGGCCCCGTCCCTAAGAGAAACAGAAGAGGAGTCAGAAAGAAAGATGCCTGTGTTTTCC
TCTGTGGGGCCCGTGCACTTCCTGGAGAGATGCTACAATGCAATATACAGCGCTCCATCCCCACTGGGGAAGCTGCTGTGATGAGACTAG
ATGAGCCTTCAACACACTCAGAAAATGCAACAGCAATAGGGGGCAGACAGCTCCTACCTGTGTTTCTAGGAGCAAAAGAGAGGGAACTAA
TTGCCCGTGAAGACGCCAGTGGAAGGATCAGCCTCATTCTAAGCAAAAACATAGTATTAGTGATACTCTTACTGCCTTATCTTAACCAAG
GACTAATAGGATACCTTTCCATTAAACACCAGTGACTTCTCAGGAAAAAAAAAAAAAAGGAGCAAAACAAATGATGTGTACACCTGCTTT
GTTATGGTCCACCAGTGACCAGCTTCAATGAGGGGAACCATTCTGGAGGGCTGCGGTCTCCTGTGCAAACAGACATGAGGCAGAAGAGTA
AAAAGACCAACCCAGTGGGACCTAGAATACTTTGTAACTCTTTAATAACTGAGGTCAGGACCGCTCTTCTGCCTTCCCCTTCCCTTAACG
TGCTTTTTCCCATTTCCATGATTTAAGGCAATGGTTTTTCCAGTATGTGACATTTTCCTTCCTGTTTTTCAGGTATATCAAAGAGTTTAC
ATATTCCAATTCACATTTTTACATCTGAGACGGGTTTTTTAAGTTCATAATTATGAAAGAAATATGTATATTGAGCTTGGGGAAATAAAA
ATGGCCTTTTCTTAAATTATTATTATTGGTAATACAACCTCTTCATTAAATAACAATGTAGCATGAAAAATTTATGATTGAAATGTAGTT
TTCATTCCATATTAAGATACAGTTTCTGAGAAGAATCATTGAATGGACTAGAATATGTCAAAAATTGATCCTGTGTAGTTTGGGTTCAGG

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_8828nt
GCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCAT
CTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTAC
CAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTC
CCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGAC
AGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAA
TCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCA
AAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAG
CGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGG
CCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTG
GCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCA
TCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTG
AAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCA
CGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCG
TTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCT
GGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGAC
TTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAA
CGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACT
ACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTA
GCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCC
AGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGG
AGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAG
AGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTA
TTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCT
GGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGA
TATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCA
AAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGG
AAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAG
AGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGG
GCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAA
TGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATT
TTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATA
TGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCT
CCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAG
ACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAATAATAAATAGCATCAAGAAAAAATTACCAATCCACCAAAATG
AACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTG
AGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAG
AGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCT
TAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTA
TCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTC
TGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCT
CTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATC
CTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAG
TCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGAC
TACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGT
CAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAG
CCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTC
CTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGC
CCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAG
TGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTC
ACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCA
CCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGA
GCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACA
TTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATT
CACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGA
GTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAA
AAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAAT
ATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAA
GAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATT
ATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGT
TTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAAC
GAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATA
TCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTT
CAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGG
AGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTT
CAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCAC
GCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGG
AGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCT
TGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCA
AGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCA
GCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCT
TCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGA
TCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCT
ATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGT
ATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGAT
CAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCG
GTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGC
AGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCA
CAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAG
AACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACC
CGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCT
TTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGT
TTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTC
ACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTG
TTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCA
ACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGA
GCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGC
CACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTC
TCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTA
TTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCG
GTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCC
CACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAA
GTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAG
GCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAAC
CTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGT
GGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAA
GTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTG
GGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAG
GAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAGAGAAAAAA

>In-frame_MPPE1_ENST00000344987_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_8753nt
GCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCCTGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCAT
CTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGAATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTAC
CAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGAAAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTC
CCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTGTTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGAC
AGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCATAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAA
TCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCACAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCA
AAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCCACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAG
CGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCCTGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGG
CCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAAGTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTG
GCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAGTGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCA
TCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAGCAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTG
AAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATTTCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCA
CGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCAAGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCG
TTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGACATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCT
GGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCTGTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGAC
TTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATGACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAA
CGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGTGGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACT
ACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGCAGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTA
GCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAACCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCC
AGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCAACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGG
AGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGTGGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAG
AGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAAGAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTA
TTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGAGCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCT
GGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGATCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGA
TATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTCCAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCA
AAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCACAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGG
AAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTCAAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAG
AGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGGAAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGG
GCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCGGAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAA
TGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTATACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATT
TTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATATACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATA
TGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGTTTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCT
CCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGTTCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAG
ACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGG
TGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGT
CAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCC
TCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCG
TTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACG
CCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTA
AGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACA
GCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTA
TCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTC
ATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGA
CCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATA
GACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTG
GCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAG
ATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATG
AGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTG
TGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCT
TCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGT
TGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAG
GAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAA
TGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAA
GAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCC
AGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGG
CCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTG
AAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGG
TCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAA
GGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAA
GAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCG
ATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTT
GGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCA
ATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGC
ATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTA
CCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGC
CCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGA
CACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGG
ACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCC
ATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCC
GATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGG
TCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGA
TGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGA
ACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTC
TGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATG
ATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGA
CCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGAT
CCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATA
TGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTT
ACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCT
TCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGA
TGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTC
TTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGT
ACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGA
GCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGA
CGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGA
AGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGCATTG
TCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACCCTGG
GAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTT
TTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTT
TGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTA
TTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCG
CTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTG
ATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAAT
ATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACA
AAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCC
GTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTT
TAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTATATCGCTCACCAGAGACAATGATCAAAT

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000302079_chr18_10871413_-_10162nt
GCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGGTTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGC
GGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCGCCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTG
GGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTCCCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAG
GCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCC
TGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGA
ATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGA
AAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTG
TTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCA
TAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCA
CAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCC
ACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCC
TGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAA
GTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAG
TGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAG
CAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATT
TCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCA
AGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGA
CATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCT
GTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATG
ACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGT
GGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGC
AGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAA
CCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCA
ACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGT
GGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAA
GAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGA
GCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGA
TCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTC
CAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCA
CAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTC
AAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGG
AAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCG
GAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTAT
ACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATAT
ACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGT
TTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGT
TCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACC
TCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTG
AAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAA
CATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGG
TGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCA
ACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTG
TGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAA
CAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGC
CTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAG
GTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCA
AATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCT
ATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCT
TCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTG
CCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGC
TGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCT
GCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGA
TCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGG
TGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCAT
ACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGA
TCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAA
TCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAA
AAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGA
AGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGA
CCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAA
AAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGG
AAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAA
CAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGG
AATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTA
CCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGA
GAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCA
TGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTT
TAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGG
AGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCA
TGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACA
GCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCC
GCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACG
ATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCT
CGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCT
GGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCT
TCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGA
AGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAG
ATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCA
AGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCA
GCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCA
GTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAA
AGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTAC
TCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCT
CTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACC
TCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGA
CTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTT
GTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGC
CCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCT
ATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGG
ACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAA
CAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCA
ATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTT
TTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAA
AGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTA
CCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACT
CTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATG
CTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGG
ATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATAT
TCCTATATCGCTCACCAGAGACAATGATCAAATGGACTAGAGAAAAAACAAATTGAAACCTTAGAACACAGACTGCAAATAATGTTAACA
TTTGAATTTTTTTTAAAAGCACAATATTCTCATAAGAGCTAAGCATTTCTAGTTCGACGGAAATGGTTTGTTTCTCTTCTGATAGGTAGA
CAAAAGGAGCTGATATCCTTCTGCAGTAAAAGCTACCTTGCAAGTTAAGGCACTGTTGAAAATGTTATTTGTAACTCCATTTCTCTGAAA
TCAGGGCTACTTGCTTTATGTTTTAGTCAACAGTGTCTCGCATTCTGATTGATCATGTGAAGGAATCATTTATGGGCCCCGTCCCTAAGA
GAAACAGAAGAGGAGTCAGAAAGAAAGATGCCTGTGTTTTCCTCTGTGGGGCCCGTGCACTTCCTGGAGAGATGCTACAATGCAATATAC
AGCGCTCCATCCCCACTGGGGAAGCTGCTGTGATGAGACTAGATGAGCCTTCAACACACTCAGAAAATGCAACAGCAATAGGGGGCAGAC
AGCTCCTACCTGTGTTTCTAGGAGCAAAAGAGAGGGAACTAATTGCCCGTGAAGACGCCAGTGGAAGGATCAGCCTCATTCTAAGCAAAA
ACATAGTATTAGTGATACTCTTACTGCCTTATCTTAACCAAGGACTAATAGGATACCTTTCCATTAAACACCAGTGACTTCTCAGGAAAA
AAAAAAAAAAGGAGCAAAACAAATGATGTGTACACCTGCTTTGTTATGGTCCACCAGTGACCAGCTTCAATGAGGGGAACCATTCTGGAG
GGCTGCGGTCTCCTGTGCAAACAGACATGAGGCAGAAGAGTAAAAAGACCAACCCAGTGGGACCTAGAATACTTTGTAACTCTTTAATAA
CTGAGGTCAGGACCGCTCTTCTGCCTTCCCCTTCCCTTAACGTGCTTTTTCCCATTTCCATGATTTAAGGCAATGGTTTTTCCAGTATGT
GACATTTTCCTTCCTGTTTTTCAGGTATATCAAAGAGTTTACATATTCCAATTCACATTTTTACATCTGAGACGGGTTTTTTAAGTTCAT
AATTATGAAAGAAATATGTATATTGAGCTTGGGGAAATAAAAATGGCCTTTTCTTAAATTATTATTATTGGTAATACAACCTCTTCATTA
AATAACAATGTAGCATGAAAAATTTATGATTGAAATGTAGTTTTCATTCCATATTAAGATACAGTTTCTGAGAAGAATCATTGAATGGAC

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000580640_chr18_10871413_-_9140nt
GCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGGTTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGC
GGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCGCCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTG
GGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTCCCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAG
GCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCC
TGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGA
ATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGA
AAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTG
TTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCA
TAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCA
CAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCC
ACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCC
TGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAA
GTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAG
TGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAG
CAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATT
TCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCA
AGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGA
CATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCT
GTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATG
ACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGT
GGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGC
AGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAA
CCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCA
ACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGT
GGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAA
GAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGA
GCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGA
TCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTC
CAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCA
CAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTC
AAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGG
AAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCG
GAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTAT
ACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATAT
ACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGT
TTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGT
TCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGCCATGCCAAAGTCAATGGTCGCGTATATCTAA
TAATAAATAGCATCAAGAAAAAATTACCAATCCACCAAAATGAACTGGCCCACCCGGAAGGAAGCCTCCCGGACCTCACCATGATGCATC
TGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTGAAAAAGCCCAGAAGG
GTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAACATCAGACTTAAGGA
ACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGGTGTTCATGTGGTGGA
TTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCAACTATGTATTTTTGA
TTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTGTGATCATCGTCTGCA
AAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAACAAACATCCCCTTTA
ATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGCCTCTGCTAGTCTACC
TGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAGGTCGAAATAACCTGA
CGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCAAATATTTCATTAATT
ACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCTATGCCATGATCCACG
CCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCTTCCTGGCATGCATCA
TCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTGCCAGCTTCAATGACA
ACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGCTGCTTCTGTGTGCCT
CCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCTGCATGAACCTTGATG
CGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGATCATCTTCAGCTACC
TCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGGTGGCCTGTTTCTACT
TCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCATACAACGTTTTTGTGA
TTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGATCCAGGCTTTCAGCC
TGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAATCATTTGGGACAGCA
TATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAAAAGCTTCCCAGATTC
TGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGAAGTCCATGGACCAGC
TGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGACCCAGGAGCCAGGGG
AAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAAAAAAGCAGTGGTGGC
GGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGGAAGAGGAAGAATTAA
AGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAACAGCACTCCGACAAA
GACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGGAATGGGAAGACCGGG
AGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTACCTGGGTCCTATTTC
TGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGAGAATTGAACGATGCA
TGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCATGAACCTTTCCAGAG
AGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTTTAGATTCACATGACA
GTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGGAGGCTGAGCAGGAGG
AGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCATGGGTGCCGAGGAGG
CCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACAGCAAGGCTGTGAGCT
TCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCCGCACCGACAAGCTGG
GGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACGATGAGCTTGAAGAGT
CAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCTCGGAGATGGTGTGCT
ACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCTGGGCCATGTTGTCCG
TCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCTTCCAATTTGGGTTCT
TTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGAAGGAAGGTTATGTTC
TCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAGATGACATGACTGAAA
GTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCAAGTCCATCAACCTGG
CCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCAGCTCCGAGCCATCCC
AGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCAGTGTTTTGAGTATTA
AGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAAAGAAGACGCTGGAGA
TCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTACTCATGTTCCTGGCTG
ACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCTCTTCACTGTCAGAGG
ACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACCTCAGGAAGACTGTAC
TGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGACTGAGAGGAAATTCA
GCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTTGTGGCTACCCAACGC
GAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGCCCTTTTTGACTGAGC
TGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCTATGCTCACATATTCA
TCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGTATGGCATGGGAGGAA
TGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGGTCATCAACCAGCCCC
TGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGAAAGTTATGGACCAGC
AGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAGAAGACATAACAGTAG
CAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCCTGGACCCCAATAGTA
GCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATAAGCTTTCTTTTCCTC
TTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGACCATAGAAAAGATTT
ATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCATGGATATTACCATCA
TTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACAATCCGAACTCTCAGG
CCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGGGATTATATGCTTCAG
TTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTCCAAATGTGGATCGAA
TTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCAAATTAATATTCCTAT

>In-frame_MPPE1_ENST00000399978_chr18_11889386_-_PIEZO2_ENST00000503781_chr18_10871413_-_9065nt
GCACTTCGCGGAGGGCGCTAGGGGCCGGGACGCGGCCGCCGAGCGTAGGTTCCGGCCTTTACTCCGAGTTGCGCACGGAGCCCCAGCTGC
GGTTGTCCGCTCTGGGGATCACAGGCCGCGGAGACCCGGGAGCCACCCGCCGGGCCCCTTCAGACGACCCGCTTCCGCAAACCGGCCGTG
GGACTCCGGCGCCGGGCGGACGAAGCGGCTCCGGGAAGACTCGGTCTTCCCCGCCCGCCTGAGGTCGCCGGGGCGGGGCTTCAGTGACAG
GCCCGCGCGCTACCGCGGAAACAGGAAGTTGGCTGGGTGCGCGCCGGCTCCGGCTGCAGTTCCCGGGTCCCTCGGCCACCGAAGCCACCC
TGCCCTGGTGAAAGGGCTCCCGCACCGCCCGGTGCTCCCCATCTGCCTGGCGTTGTGCGCAGAGCTGGAAAGCATGGCTGTTATAAATGA
ATTCTGATTTTGGGGAGCAGATGCCAACTTAGAGCCTCGTACCAATCTCTCTGTCTTTAAAAGATGAGGTGACTTGGTGATTTTCCTGGA
AAATTATAGGTGCCCAGCTAAGACCTGAATGCCATCACCCTCCCCAGGGCTCTGCAGTTTTCTCGTGGTGAACCCTTGATGGATTTGTTG
TTGCTTGAGAAATGGCGATGATCGAATTGGGGTTTGGAAGACAGAATTTTCATCCATTAAAGAGGAAGAGTTCATTGCTGTTGAAACTCA
TAGCTGTTGTCTTTGCTGTGCTTCTATTTTGTGAATTTTTAATCTATTACTTAGCGATCTTTCAGTGTAATTGGCCTGAAGTGAAAACCA
CAGCCTCTGATGGTGAACAGACCACACGTGAGCCTGTGCTCAAAGCCATGTTTTTGGCTGACACCCATTTGCTTGGGGAATTCCTAGGCC
ACTGGCTGGACAAATTACGAAGGGAATGGCAGATGGAGAGAGCGTTCCAGACAGCTCTGTGGTTGCTGCAGCCGGAAGTCGTCTTCATCC
TGGGGGATATCTTTGATGAAGGGAAGTGGAGCACCCCTGAGGCCTGGGCGGATGATGTGGAGCGGTTTCAGAAAATGTTCAGACACCCAA
GTCATGTACAGCTGAAGGTAGTTGCTGGAAACCATGACATTGGCTTCCATTATGACTTAAAGGGAGCTGATGCTGGCAATGGGATCAGAG
TGTTTGTACCTGACATCGGGATGTTCATTGCTAGTCTGACCATCTGGCTCCTCTGTAGAAACATTGTTCAGAAACCTGTGACAGACGAAG
CAGCACAGAGTAACCCGGAGTTTGAAAATGAAGAATTGGCTGAAGGAGAAAAAATTGATTCAGAAGAGGCACTGATCTATGAAGAGGATT
TCAATGGAGGAGATGGTGTTGAAGGCGAGTTGGAAGAAAGCACGAAGTTAAAAATGTTCCGCAGGCTTGCCTCTGTGGCCTCTAAGCTCA
AGGAGTTCATTGGCAACATGATCACCACTGCTGGGAAAGTCGTTGTTACCATCTTACTGGGCTCCTCGGGCATGATGTTGCCGTCTTTGA
CATCATCTGTGTATTTTTTTGTATTTTTGGGTCTGTGCACCTGGTGGTCCTGGTGCCGGACGTTCGACCCATTGCTGTTCAGCTGTCTCT
GTGTTCTGCTGGCTATTTTCACTGCTGGACATTTGATTGGACTTTATTTATACCAGTTCCAATTCTTTCAAGAGGCAGTTCCACCCAATG
ACTACTATGCAAGGTTGTTTGGTATCAAGTCAGTAATTCAAACGGACTGTTCAAGTACTTGGAAGATCATAGTGAACCCGGACCTGTCGT
GGTACCACCACGCCAACCCTATCCTCCTGCTGGTGATGTACTACACTCTGGCCACTCTGATCCGCATCTGGCTGCAAGAGCCCCTTGTGC
AGGATGAGGGGACCAAAGAAGAGGACAAAGCCCTGGCTTGTAGCCCCATCCAAATAACAGCGGGGAGGAGGCGGAGCCTGTGGTACGCAA
CCCATTACCCCACTGATGAGAGAAAACTTTTATCCATGACCCAGGATGACTACAAACCATCTGATGGCCTGCTGGTGACTGTGAACGGCA
ACCCCGTGGATTACCACACCATCCACCCAAGCCTGCCCATGGAGAACGGCCCTGGCAAAGCCGACCTCTACTCCACCCCTCAGTACCGGT
GGGAGCCCTCTGATGAATCCTCAGAAAAGCGAGAGGAGGAAGAGGAAGAGAAAGAAGAATTTGAAGAAGAAAGGAGCCGTGAGGAAAAAA
GAAGTATCAAAGTTCATGCCATGGTCTCCGTATTCCAATTTATTATGAAACAAAGTTACATCTGTGCCCTCATAGCTATGATGGCCTGGA
GCATCACCTATCACAGCTGGCTGACCTTCGTGCTGCTGATCTGGTCGTGCACTCTTTGGATGATTCGCAACAGAAGAAAATATGCCATGA
TCAGCTCTCCCTTCATGGTGGTTTATGGAAACCTATTGTTGATATTACAGTATATATGGAGTTTTGAACTTCCTGAAATTAAAAAAGTTC
CAGGATTTTTAGAAAAGAAAGAGCCAGGAGAACTTGCTTCCAAAATCCTTTTCACCATTACTTTTTGGCTACTGCTGAGGCAGCACCTCA
CAGAGCAAAAAGCTCTGCAAGAAAAGGAAGCTCTTTTATCGGAAGTCAAAATTGGCAGTCAGGAAAATGAAGAAAAAGATGAGGAACTTC
AAGATATACAAGTGGAAGGAGAGCCCAAAGAGGAGGAAGAAGAGGAAGCGAAGGAAGAGAAGCAAGAGAGAAAGAAGGTAGAGCAAGAGG
AAGCTGAAGAAGAAGATGAGCAGGACATCATGAAAGTCCTGGGCAATCTGGTGGTGGCCATGTTCATCAAGTACTGGATCTACGTCTGCG
GAGGCATGTTCTTCTTCGTCAGCTTCGAGGGTAAAATCGTAATGTACAAAATCATCTACATGGTGCTGTTCCTGTTCTGTGTGGCCCTAT
ACCAGGTGCACTATGAATGGTGGAGGAAAATTCTAAAATATTTTTGGATGTCAGTGGTTATTTACACTATGCTGGTGCTTATCTTTATAT
ACACATATCAGTTTGAGAACTTCCCAGGCCTGTGGCAAAATATGACTGGACTGAAAAAAGAAAAGCTTGAGGATCTTGGCTTAAAGCAGT
TTACTGTGGCTGAACTATTCACTCGCATATTCATCCCAACCTCCTTTCTGCTGGTGTGCATTTTACACCTGCACTACTTCCATGACCGGT
TCCTTGAACTCACAGACCTCAAGTCCATTCCCAGCAAAGAAGACAACACCATCTACAGACTGGCCCACCCGGAAGGAAGCCTCCCGGACC
TCACCATGATGCATCTGACTGCCAGCCTGGAGAAGCCGGAGGTGAGGAAGTTGGCTGAGCCTGGGGAGGAGAAGCTTGAGGGCTACTCTG
AAAAAGCCCAGAAGGGTGATCTTGGGAAAGACAGCGAGGAGTCAGAGGAGGACGGAGAGGAAGAGGAGGAATCCGAGGAGGAGGAAGAAA
CATCAGACTTAAGGAACAAATGGCACCTGGTGATTGACCGCCTCACTGTGCTCTTCTTAAAATTCCTGGAGTATTTTCACAAGCTGCAGG
TGTTCATGTGGTGGATTTTGGAGTTGCACATCATCAAAATCGTTTCCTCTTACATTATCTGGGTTTCTGTGAAAGAGGTGTCTCTGTTCA
ACTATGTATTTTTGATTTCTTGGGCTTTTGCTCTGCCGTACGCCAAGCTGCGCCGTCTGGCTTCAAGTGTCTGCACAGTCTGGACGTGTG
TGATCATCGTCTGCAAAATGTTGTACCAGCTCCAAACCATTAAGCCTGAGAACTTCTCTGTTAACTGTTCCTTGCCAAATGAAAATCAAA
CAAACATCCCCTTTAATGAGTTGAACAAGTCTCTGCTCTACAGCGCTCCTATCGATCCTACAGAGTGGGTCGGCCTGCGGAAGTCTTCGC
CTCTGCTAGTCTACCTGAGGAATAACCTCCTGATGCTGGCTATCCTGGCCTTTGAAGTCACCATTTACCGCCATCAGGAATACTATCGAG
GTCGAAATAACCTGACGGCCCCTGTGTCTAGAACTATCTTTCATGACATTACAAGACTACATCTAGATGATGGACTTATTAATTGTGCCA
AATATTTCATTAATTACTTCTTTTACAAGTTTGGTCTGGAGACCTGTTTCCTAATGTCAGTTAACGTCATTGGCCAGCGAATGGATTTCT
ATGCCATGATCCACGCCTGCTGGCTGATCGCTGTCTTATATAGACGCAGAAGGAAAGCCATCGCAGAGATCTGGCCCAAGTACTGCTGCT
TCCTGGCATGCATCATCACCTTCCAGTATTTCATCTGCATTGGCATCCCACCTGCTCCTTGCCGAGATTACCCGTGGAGATTCAAGGGTG
CCAGCTTCAATGACAACATCATAAAGTGGCTGTACTTCCCAGATTTCATTGTGCGGCCCAACCCTGTGTTTCTCGTCTATGACTTCATGC
TGCTTCTGTGTGCCTCCTTACAACGGCAGATTTTTGAGGATGAGAACAAGGCTGCAGTGCGAATCATGGCAGGTGACAATGTCGAGATCT
GCATGAACCTTGATGCGGCCTCCTTCAGCCAACATAACCCTGTGCCAGATTTTATTCACTGCAGATCTTACTTAGACATGTCCAAAGTGA
TCATCTTCAGCTACCTCTTCTGGTTTGTGCTCACCATCATCTTCATCACTGGGACCACCAGGATCAGCATCTTTTGCATGGGGTACCTGG
TGGCCTGTTTCTACTTCCTGCTCTTTGGGGGCGATTTGCTGTTGAAACCCATCAAGAGCATCCTGCGCTACTGGGACTGGCTGATCGCAT
ACAACGTTTTTGTGATTACGATGAAAAATATCCTGTCAATAGGAGCATGTGGATACATTGGAACATTGGTGCACAATAGTTGTTGGTTGA
TCCAGGCTTTCAGCCTGGCCTGCACAGTCAAAGGCTATCAAATGCCTGCTGCTAATTCACCCTGTACACTTCCCAGTGGGGAAGCAGGAA
TCATTTGGGACAGCATATGTTTTGCCTTCCTCCTGCTGCAAAGAAGAGTTTTCATGAGTTATTATTTTCTACATGTTGTGGCTGATATAA
AAGCTTCCCAGATTCTGGCATCAAGAGGAGCTGAACTTTTCCAGGCCACAATTGTAAAAGCTGTAAAGGCAAGAATTGAGGAAGAGAAGA
AGTCCATGGACCAGCTGAAGCGACAGATGGATCGCATCAAGGCCAGGCAACAGAAATATAAAAAGGGTAAGGAGAGGATGCTGAGCTTGA
CCCAGGAGCCAGGGGAAGGCCAGGACATGCAAAAACTCTCTGAAGAGGATGATGAAAGAGAAGCAGACAAACAGAAAGCCAAGGGCAAAA
AAAAGCAGTGGTGGCGGCCTTGGGTTGATCATGCTTCCATGGTCAGGAGTGGAGATTATTATTTGTTTGAAACGGATAGTGAAGAGGAGG
AAGAGGAAGAATTAAAGAAGGAAGATGAAGAACCTCCACGAAGGTCAGCATTCCAGTTTGTTTATCAAGCCTGGATTACTGATCCTAAAA
CAGCACTCCGACAAAGACACAAAGAGAAAAAAAGGTCTGCAAGAGAAGAACGGAAACGAAGGCGGAAAGGATCCAAGGAGGGTCCTGTGG
AATGGGAAGACCGGGAGGATGAACCAATCAAAAAGAAATCCGATGGACCAGATAATATCATCAAGAGGATATTTAATATTTTGAAATTTA
CCTGGGTCCTATTTCTGGCAACAGTGGACAGTTTCACTACTTGGCTTAACTCCATTTCAAGGGAGCATATTGATATATCTACAGTTCTGA
GAATTGAACGATGCATGCTGACCAGAGAAATTAAGAAGGGCAATGTTCCAACTCGGGAGAGCATCCACATGTACTATCAGAACCACATCA
TGAACCTTTCCAGAGAGTCGGGACTGGACACCATTGACGAGCATCCCGGAGCTGCTTCAGGTGCACAGACAGCCCACAGGATGGATAGTT
TAGATTCACATGACAGTATCTCCAGCGAGCCCACGCAGTGTACCATGCTGTACTCACGCCAGGGGACCACTGAGACCATCGAGGAGGTGG
AGGCTGAGCAGGAGGAGGAGGCAGGGAGCACGGCGCCTGAGCCCAGGGAGGCCAAGGAGTACGAGGCCACTGGGTACGATGTGGGAGCCA
TGGGTGCCGAGGAGGCCAGCCTCACCCCAGAGGAAGAGCTGACACAGTTCTCCACCTTGGACGGGGATGTGGAGGCCCCACCCTCCTACA
GCAAGGCTGTGAGCTTCGAGCATCTGTCCTTCGGCTCGCAGGACGACTCTGCAGGCAAGAACCGTATGGCAGTCAGCCCGGACGACAGCC
GCACCGACAAGCTGGGGTCCAGCATCTTACCTCCCCTGACCCATGAGCTGACGGCCAGCGAGCTGCTGCTGAAAAAGATGTTTCACGACG
ATGAGCTTGAAGAGTCAGAGAAATTCTACGTGGGGCAGCCCCGATTTCTGCTGCTCTTCTATGCCATGTACAATACCCTGGTGGCCCGCT
CGGAGATGGTGTGCTACTTCGTGATCATCCTCAACCACATGGTCTCTGCCTCCATGATCACGCTCCTGCTTCCCATCCTCATCTTCCTCT
GGGCCATGTTGTCCGTCCCCAGGCCCAGCCGCCGGTTCTGGATGATGGCCATCGTCTATACTGAGGTGGCAATTGTAGTCAAGTATTTCT
TCCAATTTGGGTTCTTTCCCTGGAATAAGAATGTGGAGGTGAACAAAGATAAACCGTATCACCCCCCAAACATCATAGGAGTGGAAAAGA
AGGAAGGTTATGTTCTCTATGACCTCATCCAGCTCCTGGCTCTGTTCTTTCATCGATCAATTTTGAAGTGCCATGGCTTATGGGATGAAG
ATGACATGACTGAAAGTGGCATGGCCAGGGAGGAATCAGATGATGAGCTCTCCCTCGGTCATGGCAGGAGGGACTCCTCCGATTCTCTCA
AGTCCATCAACCTGGCCGCGTCTGTGGAGTCAGTGCATGTGACCTTCCCGGAGCAGCAGACAGCTGTCCGGAGGAAGCGCTCCGGCAGCA
GCTCCGAGCCATCCCAGAGATCCAGCTTTTCTTCAAACAGATCCCAAAGAGGCAGCACAAGCACCCGAAACAGCAGTCAAAAAGGAAGCA
GTGTTTTGAGTATTAAGCAAAAAGGCAAAAGGGAACTTTATATGGAAAAGCTTCAAGAACATTTAATCAAAGCAAAAGCCTTTACCATAA
AGAAGACGCTGGAGATCTATGTGCCCATCAAACAGTTCTTTTACAACCTCATCCACCCGGAGTATAGCGCCGTGACTGACGTGTATGTAC
TCATGTTCCTGGCTGACACTGTGGACTTCATCATCATTGTCTTCGGCTTTTGGGCCTTTGGGAAACACTCAGCAGCTGCAGACATCACCT
CTTCACTGTCAGAGGACCAGGTCCCGGGGCCGTTTTTGGTGATGGTCCTCATTCAGTTTGGAACCATGGTGGTGGACCGAGCCCTCTACC
TCAGGAAGACTGTACTGGGAAAGGTCATCTTCCAGGTCATTCTTGTGTTCGGAATTCACTTCTGGATGTTCTTCATCTTACCTGGTGTGA
CTGAGAGGAAATTCAGCCAGAACCTGGTTGCCCAGCTTTGGTACTTTGTGAAATGTGTTTACTTCGGGTTGTCTGCTTACCAGATCCGTT
GTGGCTACCCAACGCGAGTCCTGGGGAACTTCCTCACCAAGAGCTACAATTACGTCAACCTCTTCTTATTCCAAGGGTTTCGCCTCGTGC
CCTTTTTGACTGAGCTGAGGGCAGTGATGGACTGGGTGTGGACGGACACAACTTTGAGCCTGTCCAGCTGGATCTGTGTGGAGGACATCT
ATGCTCACATATTCATCCTGAAGTGTTGGCGGGAGTCGGAGAAGAGATACCCTCAGCCACGGGGCCAGAAGAAGAAGAAAGTGGTGAAGT
ATGGCATGGGAGGAATGATCATCGTCCTGCTCATCTGCATTGTCTGGTTTCCTCTTCTCTTCATGTCTTTGATCAAATCTGTGGCTGGGG
TCATCAACCAGCCCCTGGACGTCTCCGTCACAATTACCCTGGGAGGGTATCAGCCTATTTTCACAATGAGTGCCCAACAAAGCCAGTTGA
AAGTTATGGACCAGCAGAGCTTTAACAAATTTATACAAGCTTTTTCTAGGGACACCGGTGCTATGCAATTTCTGGAAAATTATGAAAAAG
AAGACATAACAGTAGCAGAACTGGAAGGAAACTCAAATTCTTTGTGGACCATCAGCCCACCCAGTAAGCAGAAAATGATACACGAACTCC
TGGACCCCAATAGTAGCTTCTCTGTTGTTTTTTCATGGAGTATTCAGAGAAACTTAAGTCTGGGTGCAAAATCGGAAATAGCAACAGATA
AGCTTTCTTTTCCTCTTAAAAATATTACTCGAAAGAATATCGCTAAAATGATAGCAGGCAACAGCACAGAAAGTTCAAAAACACCAGTGA
CCATAGAAAAGATTTATCCATATTATGTGAAAGCACCTAGTGATTCTAACTCAAAACCTATAAAGCAACTTTTATCTGAAAATAATTTCA
TGGATATTACCATCATTTTGTCCAGAGACAATACAACTAAATATAACAGTGAGTGGTGGGTTCTCAACCTGACTGGAAACAGAATATACA
ATCCGAACTCTCAGGCCCTGGAACTGGTGGTCTTCAATGACAAAGTCAGTCCCCCAAGTCTGGGGTTCCTGGCTGGCTATGGTATTATGG
GATTATATGCTTCAGTTGTCCTTGTGATTGGGAAATTTGTCCGTGAATTCTTCAGTGGGATTTCTCACTCCATCATGTTTGAAGAGCTTC
CAAATGTGGATCGAATTTTGAAGTTGTGCACAGATATTTTTTTAGTTCGAGAGACAGGAGAACTGGAGCTAGAAGAAGATCTCTATGCCA


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FusionGenePPI for MPPE1_PIEZO2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MPPE1GMCL1, ZNF426, MUCL1, EDEM1, ICAM4, TMEM186, UGT3A2, GINM1, PIGB, SEMA6A, TMEM59L, GALNT4, DHFRL1, FZD2, ALG12, NXPE3, ECEL1, FUT8, FAM69A, SUSD1, AMIGO1, EXTL3, BTN2A2, GALNT12, PBXIP1, BACE2, CGRRF1, TMEM39A, GLB1L2, CCPG1, GAS6, LRP12, TMEM214, SUN2, HTATIP2, UGT8, GPC4, POMT1, EXT1, SUN1, PLXNA2, ALG9, HYAL2, POMT2, CANX, GYLTL1B, GALNT7, LRFN3, TMEM192, CNTNAP3B, LRRC3, ATF6B, TMEM132A, HSPA5, B4GALT7, ABCA3, CMTM4, USP30, TXNDC15, FAM189B, MR1, FKRP, TMBIM6, SPPL2B, IMPAD1, CHST12, ERMP1, LMF2, CSGALNACT2, UXS1, PLXNB2, ADAM10PIEZO2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MPPE1_PIEZO2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MPPE1_PIEZO2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMPPE1C0005586Bipolar Disorder1PSYGENET
TgenePIEZO2C1862472Oculomelic amyoplasia2ORPHANET;UNIPROT
TgenePIEZO2C0220666ARTHROGRYPOSIS MULTIPLEX CONGENITA, DISTAL, TYPE IIA1ORPHANET;UNIPROT
TgenePIEZO2C0796033MARDEN-WALKER SYNDROME1ORPHANET;UNIPROT