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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 22324

FusionGeneSummary for MPC2_DNM3

check button Fusion gene summary
Fusion gene informationFusion gene name: MPC2_DNM3
Fusion gene ID: 22324
HgeneTgene
Gene symbol

MPC2

DNM3

Gene ID

25874

26052

Gene namemitochondrial pyruvate carrier 2dynamin 3
SynonymsBRP44|SLC54A2Dyna III
Cytomap

1q24.2

1q24.3

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial pyruvate carrier 2brain protein 44dynamin-3T-dynamindynamin family memberdynamin, testicular
Modification date2018052320180523
UniProtAcc

O95563

Q9UQ16

Ensembl transtripts involved in fusion geneENST00000367846, ENST00000271373, 
ENST00000358155, ENST00000367733, 
ENST00000355305, ENST00000367731, 
ENST00000520906, 
Fusion gene scores* DoF score3 X 2 X 2=1216 X 12 X 5=960
# samples 215
** MAII scorelog2(2/12*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/960*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MPC2 [Title/Abstract] AND DNM3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSARCTCGA-DX-A6BG-01AMPC2chr1

167904971

-DNM3chr1

172356273

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000367846ENST00000358155MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000367846ENST00000367733MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000367846ENST00000355305MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000367846ENST00000367731MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000367846ENST00000520906MPC2chr1

167904971

-DNM3chr1

172356273

+
Frame-shiftENST00000271373ENST00000358155MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000271373ENST00000367733MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000271373ENST00000355305MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000271373ENST00000367731MPC2chr1

167904971

-DNM3chr1

172356273

+
5CDS-intronENST00000271373ENST00000520906MPC2chr1

167904971

-DNM3chr1

172356273

+

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FusionProtFeatures for MPC2_DNM3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MPC2

O95563

DNM3

Q9UQ16

Mediates the uptake of pyruvate into mitochondria.{ECO:0000269|PubMed:22628558}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMPC2chr1:167904971chr1:172356273ENST00000271373-2641_6136128TransmembraneHelical
HgeneMPC2chr1:167904971chr1:172356273ENST00000271373-2673_9036128TransmembraneHelical
HgeneMPC2chr1:167904971chr1:172356273ENST00000271373-2696_11536128TransmembraneHelical
HgeneMPC2chr1:167904971chr1:172356273ENST00000367846-1541_6136128TransmembraneHelical
HgeneMPC2chr1:167904971chr1:172356273ENST00000367846-1573_9036128TransmembraneHelical
HgeneMPC2chr1:167904971chr1:172356273ENST00000367846-1596_11536128TransmembraneHelical
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+172128_294692870DomainDynamin-type G
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721515_621692870DomainPH
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721659_750692870DomainGED
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+172128_294686864DomainDynamin-type G
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721515_621686864DomainPH
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721659_750686864DomainGED
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+162028_294682860DomainDynamin-type G
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620515_621682860DomainPH
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620659_750682860DomainGED
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721205_211692870Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721236_239692870Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+172138_46692870Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721205_211686864Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721236_239686864Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+172138_46686864Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620205_211682860Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620236_239682860Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+162038_46682860Nucleotide bindingGTP
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721136_139692870RegionG3 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721205_208692870RegionG4 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+1721235_238692870RegionG5 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+172138_45692870RegionG1 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000355305+172164_66692870RegionG2 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721136_139686864RegionG3 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721205_208686864RegionG4 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+1721235_238686864RegionG5 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+172138_45686864RegionG1 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000358155+172164_66686864RegionG2 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620136_139682860RegionG3 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620205_208682860RegionG4 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+1620235_238682860RegionG5 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+162038_45682860RegionG1 motif
TgeneDNM3chr1:167904971chr1:172356273ENST00000367731+162064_66682860RegionG2 motif


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FusionGeneSequence for MPC2_DNM3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MPC2_ENST00000367846_chr1_167904971_-_DNM3_ENST00000358155_chr1_172356273_+_214aa
MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGXRFHKFRAPSTVVFFRGPKYPDGGICXAGSAPGXDASNVSSTERSPWDNWGHQ
HSHRVHSGTPSSGXLLDTALSQVTSSKPHNPKEANTKCSPRKAHIRPRTSSCHSLSWPPLWGSSSPIPSRPITSFPQQQXLLRSPSTSSI


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MPC2_ENST00000367846_chr1_167904971_-_DNM3_ENST00000358155_chr1_172356273_+_643nt
ATGTCGGCCGCCGGTGCCCGAGGCCTGCGGGCCACCTACCACCGGCTCCTCGATAAAGTGGAGCTGATGCTGCCCGAGAAATTGAGGCCG
TTGTACAACCATCCAGCAGGTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGGACCAAAATACCCTGATGGA
GGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGAATGTATCAAGCACTGAAAGAAGCCCTTGGGATAATTGGGGACATCAG
CACAGCCACCGTGTCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAGGTCACCTCCTCCAAGCCCCACAAC
CCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCTGCCATTCCCTCTCCTGGCCCCCACTC
TGGGGCTCCTCCAGTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAGCCCCTCCACAAGTTCCATC
TAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAGCCGGAGACCACCCCCATCACCAACTCGTCCCACTATAATCCGCCCACTAGAATCCTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MPC2_ENST00000367846_chr1_167904971_-_DNM3_ENST00000358155_chr1_172356273_+_5717nt
CGCCCCCTCAACCTTCGCGGGGCGCGGGCCGCAGCTTTTCGGTTCACAGCGGGCAGGGAAAGCCGCGGGAAGGGTACTCCAGGCGAGAGG
CGGACGCGAGTCGTCGTGGCAGGAAAAGTGACTAGCTCCCCTTCGTTGTCAGCCAGGGACGAGAACACAGCCACGCTCCCACCCGGCTGC
CAACGATCCCTCGGCGGCGATGTCGGCCGCCGGTGCCCGAGGCCTGCGGGCCACCTACCACCGGCTCCTCGATAAAGTGGAGCTGATGCT
GCCCGAGAAATTGAGGCCGTTGTACAACCATCCAGCAGGTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGG
ACCAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGAATGTATCAAGCACTGAAAGAAGCCCTTG
GGATAATTGGGGACATCAGCACAGCCACCGTGTCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAGGTCAC
CTCCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCTGCCATTC
CCTCTCCTGGCCCCCACTCTGGGGCTCCTCCAGTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAG
CCCCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAGCCGGAGACCACCCCCATCACCAACTCGTCCCACTATAA
TCCGCCCACTAGAATCCTCCCTGTTAGACTAAACGAAGTGTCTGGCATGGCAATTAATCACTAATGAATTATGCGAAAGCAACATATTTG
ATAACCGTTGCAGTAAATCATGAGTAGTCGCATGTGTGGACATCAGTAGGCAAGTAACCAGTTTTACTAATGCATTCATCGCTCATCTTC
ATTGCTCATGGTATGTCAAACCTTTGGGGTTTGACTCAGAAACTGCTAACCTTTTAGAGGCTTTATATGTTGTACTGACCAAGGTAGGTT
TGTATAGCAGCCCTATACTTTGGGGATCATTTGCCTACCATGGCATATATTTGAAATTGCTTTGGACAAGTTTTCTAGGCTATCTACCAG
GTAGCTCATTAAACGTAATTCTTCAGATATGAGATAGTGGGCTTAGACCTAAGCCATACATATTTCTTTTCCCACATTCTGTTTAGGATG
ACAGTAATTCTGTTGTCTACCATTAATGCTACTACCTACTCCATAATTGCCTATTTAGCTCCTCTTTTCTTCCTTTTTATTTCATAAGAC
TGCTAGGAAGTGATTTTTTAAAATTAGGACTCCTTAAGAATAAACTTTTCCAGAAGCACGAGGTAGTTTGCAAAGGAAAAGTCTGCACTG
TTTGCTCTAAAGAGCTTCTCCTCATTCCAATGTGTTTTGCTTCATGCTAGAAGCATATGCAACAGTGAATAAAAGCTTCTTTTTTTGTTA
ATCAGTCAATAAATTTGGCTAATTAGTTTCAGAGTTCAAGGAAGAAGCAAAATATCACATCTCTAGAAGTGTTGGGAAAAATATAATTTC
TTTCTTTACTTATATTCACCTCATGGTAGGTTATATTGAAGGCTGACATGGAGAATGTTTACTTTTCTATTTGGCATAGCTAACTACACT
TTGATACTAACTCCAGTTTTACTATTATTATTTTGGTTGGAAAAAAAATTCACTCTTTACGTGCTAATTTGTAATCTTGTTTTGTAAGAA
TTTATCCTACCCTTGAAACAGGCTCAGTGTAACTGTATATCCATTCTAGGCTTTCTTAATAAATCTTGAGGCTATGGGATAATCACATTT
AAAGAATGGTTCCTGAAATGAAGTCAGTAGAAATGGCATGGGATAAGAGCAGAGCTCACACTTTTACAGTTGCAGTATTTCAAAGTCCCT
ATCCAGGTCACTCCAGAAAAGGGTATTGAAACGTTGAAATCTAAAGCAAATTTGCAATTTCTTAAGATTTCTAAAATTTACCAGAACAGT
TTAGCCTGGGGGTTAATAGTTAAGTCTTGAGGCTAAGTTTTGGACTACCAAGGACCAGATGATTCACATGTAGGAAACAGCCAGAAGCCA
ACTGGAATTTTGTGTGCTAACTGTTCCCAGACAGCAGAGCAAGTATTCACTGAGTAGGGGTGTCCCATGACACTATTTCATATTCTACAG
AAGTAAATCAGGTTTCACCAACTGAAATGTCTCCCTTTGAAAGTAGCAAACATGATTTGTATGTTAACTTAACTTTAATTTCCTGTGTAG
TTTACACCCAGAGCAGATACTCATAAAGTATAAAGTAAAAACTTTTAACCATTATTAAACAGAGAACTTGCCATGTTGAGTGCCATTGTA
TTGAACTTATTCTAAAGGCTTATGCTAACCCATTTATAATTGGTAAAAATCAGAAAATACAAGATTTACATAAAGGTCATTTCAACTTTT
AAGGTTACCAGTGATTGTATAAAAACATCACAATCCTAAATCCTCTCGTATCTCACCCCAAACCCCAAACTGGGGGAAAAAAAGTTAACT
CTTTGTGAATGGAACCAATGTGCAAGATACATACTGCATTTTTAAAATAGTGTCTCAGCTAAATGGAAAACTGTTAAGCAAACATCCATA
GTAAAACAAATAATCTTCAGTGAGATCTTTTTATAAAACTTCTTGTTTTTAGGATTCCCTTTGCTTCTTCCTTTGAATTCTCTAAAATAG
GCAGCTAACGGATTATATACTTCAGGGTTTGGCTTTGTGCTAAATGTGGTTTTGTGTTTTGCTGTATTTCAAAATTTTCCTTCTGTTAAA
GGAAAATATTGTGAATAACCACTGGTGTGTTCTTAGATCAGCACAAACCATGTCAAAAAAAATTGGAGATTTTTTTCCAATTTTCCTTCC
ACTGATCTTAGGCAGTAATAAACAATGGCATTTGTCATCTTTGGCACTTGCTTTTAGATTATAGTCCCACAGTTGCACTGCCCCAATTGT
CTACCTTTGTGGGTACATTTTTGTTCTTTACTCCTAAGTTATTTCTCATAGAACCCAGCCTACTCTAGAATTTCAGCAGTGACATTGGAG
AATATTTTTAATTTGCTGCAGTACTATGTCATATTATTAGTATGAATCTCATTTCCCAAAGGGTTTGTATTCTGCTAAAAGGAGATGCCA
ATGTTGAATGAAGTCTGAAACTCTAGTATGTGCATAGTTTGACGTGCAGCATGCACACCAGGCCTTAAGATGGGAATGTAGCTTAATGAT
TTTCTGTTTCCCATACCATTTCTAATCTTTTGTGTAATTTTCTCTTAACTGATTGCTCTGATATTGTAAACACAATAGATGTAGCTCTAT
CATGTCTAGCATAATTTAAAAAATCAGTGTTTTTAGGATTTGGGAAAATAAACTGTAAATGTTTATTTGATAGGTAAATATAGTTTTATT
GTCACATGCTAAATATTGCATGCATATTGACTAATTGGAATAACCATTTACTCAATTATGGACAGCTTATTGAAATAGTATTGATTTAGA
AAAAGTATATTGCATTTCTAAAAAACATCTACCAAGGTTACTCGTCTGAATATTGCTTTTAGCCGTGTTTTATAACATAGACGAGCAGTA
GGGTCTGTTTATTAGCAAATTTCCTATTTGTTCCAATACAAACTCACTTTATTCTAAAGTATATTAATGAAACCAGTTCCTGTGATGTAA
CTGTAAGCCTTCTCGACTTAGACTTAAAAAGTGGTCACATAGATTAATTTTGTGACTTTTTAGTATAGACTGTAGCCATAATTCTCAAAT
ATGAAATGGGACCTAATACCAGTATGTGATAAATGTTGATGTTTTCTGTGTACAAACACATTTTCTATGCATGTGTCTCTGTGTATATGG
CATATACCTAGTAAGTATGTTTCTGTAAGTATGTGTATTTTATGTCCATTTGAGTAGGTAGGTAGGTTTTAAAAATACTAGTTAAAATGC
CACAAGCATGAGTGTGATTGTATGTGCACTGTGTGTATATATATAAATATATGTATATGTATGGTTGTAAATATCTATGTATACATGTAC
TTAGTATGTGTGGTATCAGGATATTTTTTAAACTGTGATAATACAACAGATAGCTTTGAATGATCTGCCATAACATGTGGTAACAATAGT
TCATTTCTCATAACATATATGAGGTATACAAAATTTTCTAACTCCAGATTGTAGTCATTTTGAGAGGTACAAAGCTCATAATTACCATGA
CAACATGGTAATGTCCATAGACATTTGTATCTGAATCCACAAGAAGATCTGAATCTAAGAAGGAATTACCTTTGACAATATTTTTCGGTA
AGAAGTAAAACCTCTGGAGACCTATCTTTAAGATCTCTAATTGGAATTATAAATTATTTTTGGATTGCTGAGCTGAATCTTAAAAAGCCA
AGTTGATATACATAGTCATTTTTCCTCTATGGTAGAAGTAAAAAAAAAAAAAAAGGACATAGCAACATTAAAGTAGTGGATTTTTCTGAG
TAAATTTGCTGAAAATATAAGAGAGAAGCTATCTAATACCTTGGAGGTAGGTCATCCACTTTTTCAGGTAAACATTTTTCATTTGGCAAA
TGGCATAATTATTTGAAAGTGACAGGAATCTCCTCAGAATGAAGAATAAAGCCTACTAGGTCTCTAACTGTTGAACTCATGAAAGAAGAT
AGTGTATGAGACTTAAGCCATGAGTTTTGTATCATTTCAATTAGAAGACTACTAGCTGTGAGCTCAGAGTTTAATGTAAATGAATCTAGA
TGATTTTGAAGAAATGATTATTCGTTCACCAGATCACTCATTGTACATTCTAAAAAGCTCAAATGAGTCTTCTAGATACTCTTACTCATC
CTGTCTGGTTGCTATGTTTAAAATTATGTGGTGCTGTGTAGGTGAAACTTTAAGAATATTTTTGAAGCATATGTAATATATGCACTGCTA
TTTGTGTGTGTGTGTGTGTCTTTGTATATATGTAAGAATGTGTGTATGTGTGAGAGCAAGAGAGAGGAAACTCAAAGAGGAGTGTTTGTC
TTAAGACCTGTTCATACTGGTATATTGGTGAGACTTCTCACTTCTGGTTGGAGGTTTCACATATGGCTCAACTCAAGTCATTAATCTCTT
TTTAATTTTTACTCTTGAATTCCTTAAACTTCGCTCATTATGAAATGTTTTAAAATTATGACAAAAATTACTCTGTCTAACCACTTGCCT
TGTCTGCTACCAGTTTGTTAAAAATTATTCCCCCCAACCAGTAATTCCACCAGTACTACTTGATTTGTGTTATATTTCCTATGTACATGT
ACAGCCTTTGTTTTGCTTGCTTGTCTATTTTTACTTTCCCTTTTTTGGGTCAAATTTTTCTTTTGCTTTGTTTGAAGAAGGAATATACAG
AAGTAAAATCTTGTCTTCTCTGCTGATTCTTTAATTAATATGAGCCGGATACTTTCCACTGTCTTCTTGGCACTTTCAGGATTTCTTAAT
GCTGATATATGGACTCTTAGAATGGAATTTTTGAAGAAAAATCTCAAAGCCTGTATCGTTCTTGAAGGTCACATGTACCTATTGTGAAAA


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FusionGenePPI for MPC2_DNM3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MPC2RPLP1, LRRK2, EGFR, FLOT2, NDUFA4, COQ9, C15orf48, ATP2B2, SLC1A1, SLC39A9, OGFOD3, TMEM171, TTC30B, TRIM25DNM3FER, SH3GL2, SH3GL3, GRB2, VCP, EFNB2, BSG, NUFIP1, DNAAF2, SPACA1, DNM1, DNM2, ALMS1, SNX5, COL1A1, KIF2C, SNX6, HECTD1, KIF11, SNX1, SNX2, HAUS8, HERC1, TP73, RAPH1, DNMBP, IGSF8, LYPD3, SCN2B, THBS3, LYPD6, GBE1, RPE, KRAS, SNX9, TMEM9B, ZBBX, GYPB, IL1R2, LAMP1, SLC2A12, GYPA, THRB, CDKAL1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MPC2_DNM3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MPC2_DNM3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMPC2C0036341Schizophrenia1PSYGENET