|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 22209 |
FusionGeneSummary for MMP11_GAS2L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MMP11_GAS2L1 | Fusion gene ID: 22209 | Hgene | Tgene | Gene symbol | MMP11 | GAS2L1 | Gene ID | 4320 | 10634 |
| Gene name | matrix metallopeptidase 11 | growth arrest specific 2 like 1 | |
| Synonyms | SL-3|ST3|STMY3 | GAR22 | |
| Cytomap | 22q11.23 | 22q12.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | stromelysin-3matrix metallopeptidase 11 (stromelysin 3)stromelysin III | GAS2-like protein 1GAS2-related protein on chromosome 22growth arrest-specific protein 2-like 1 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P24347 | Q99501 | |
| Ensembl transtripts involved in fusion gene | ENST00000477567, ENST00000215743, | ENST00000407647, ENST00000360113, ENST00000406549, ENST00000341313, ENST00000403764, ENST00000407854, ENST00000471961, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: MMP11 [Title/Abstract] AND GAS2L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | GAS2L1 | GO:0097067 | cellular response to thyroid hormone stimulus | 19375645 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-V1-A8WN-01A | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000477567 | ENST00000407647 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000360113 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000406549 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000341313 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000403764 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000407854 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| intron-3CDS | ENST00000477567 | ENST00000471961 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000407647 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000360113 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000406549 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000341313 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000403764 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000407854 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
| In-frame | ENST00000215743 | ENST00000471961 | MMP11 | chr22 | 24115165 | + | GAS2L1 | chr22 | 29706429 | + |
Top |
FusionProtFeatures for MMP11_GAS2L1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MMP11 | GAS2L1 |
| May play an important role in the progression ofepithelial malignancies. | Seems to be involved in the cross-linking ofmicrotubules and microfilaments. {ECO:0000269|PubMed:12584248}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for MMP11_GAS2L1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407647_chr22_29706429_+_363aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE HYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLPPHPRSRRYSGDS DSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPACAASPETGWIAAGPGGPQEAGEPSCRSPALPGGPGARAARSRLCC LCAGIETGSTHGCQGAGAVGARAGAPPRLPVPAALQHPGFPGSPAPVQSWAPHRPASSAHPCSSTRSRSSSCSGAWKRSSWPMPGPLRLL >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000360113_chr22_29706429_+_155aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000406549_chr22_29706429_+_280aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE HYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPSSSSSSLSVLGGKCGQPGD SGRTANGLPGPRSQALSSSSDEGSPCPGMGGPLDAPGSPLACTEPSRTWARGRMDTQPDRKPSRIPTPRGPRRPSGPAELGTWHALHSVT >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000341313_chr22_29706429_+_163aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000403764_chr22_29706429_+_363aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE HYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLPPHPRSRRYSGDS DSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPACAASPETGWIAAGPGGPQEAGEPSCRSPALPGGPGARAARSRLCC LCAGIETGSTHGCQGAGAVGARAGAPPRLPVPAALQHPGFPGSPAPVQSWAPHRPASSAHPCSSTRSRSSSCSGAWKRSSWPMPGPLRLL >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407854_chr22_29706429_+_363aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE HYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLPPHPRSRRYSGDS DSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPACAASPETGWIAAGPGGPQEAGEPSCRSPALPGGPGARAARSRLCC LCAGIETGSTHGCQGAGAVGARAGAPPRLPVPAALQHPGFPGSPAPVQSWAPHRPASSAHPCSSTRSRSSSCSGAWKRSSWPMPGPLRLL >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000471961_chr22_29706429_+_363aa MAPAAWLRSAAARALLPPMLLLLLQPPPLLARALPPVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLE HYLDKHDPCRCSSTAHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRPEMTPVSLRSTKEGPETPPRPRDQLPPHPRSRRYSGDS DSSASSAQSGPLGTRSDDTGTGPRRERPSRRLTTGTPASPRRPPACAASPETGWIAAGPGGPQEAGEPSCRSPALPGGPGARAARSRLCC LCAGIETGSTHGCQGAGAVGARAGAPPRLPVPAALQHPGFPGSPAPVQSWAPHRPASSAHPCSSTRSRSSSCSGAWKRSSWPMPGPLRLL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407647_chr22_29706429_+_1089nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA CGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGT GACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGG CGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGG GGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGC TTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCC GTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACAC CCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000360113_chr22_29706429_+_465nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCG GGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGAC >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000406549_chr22_29706429_+_840nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA CGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGCCAACCTGGGGAC TCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGCCCTGGCATGGGG GGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACACAGCCAGACCGT AAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTGCACTCAGTCACC >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000341313_chr22_29706429_+_489nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000403764_chr22_29706429_+_1089nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA CGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGT GACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGG CGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGG GGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGC TTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCC GTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACAC CCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407854_chr22_29706429_+_1089nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA CGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGT GACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGG CGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGG GGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGC TTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCC GTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACAC CCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000471961_chr22_29706429_+_1089nt ATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCGCGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTG GCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCGCTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTAC CGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGTGCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAG CATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTCCACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGG GTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGTCCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTA CGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGT GACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGG CGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGG GGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGC TTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCC GTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACAC CCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407647_chr22_29706429_+_1860nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCC CCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGG TACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCC TCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCC AGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTG CCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTC TCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTC CGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGCCCCTGACCCAGCT CGGGCCCCCGACCCTCCAGCTCCTGACTCTGCCTATTGTTCCTCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGC CAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGC CCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACA CAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTG CACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAGCTCAGCTGTCCCCAGACCCCATCCCTTCTCCTTTTCCTTT GTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACCAGACCTCATGGGACCAGACCCCTTGGGACCACATGGCACA ATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAATTACTAATATTATTGAATGCCTTAGAGGAGGCCGGGCGAG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000360113_chr22_29706429_+_1685nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGC CCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCTCTCCG AGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCAGCTGT CGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCAGCACT CATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCGGCTTT CCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGAGCAGC AGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGCCCCTG ACCCAGCTCGGGCCCCCGACCCTCCAGCTCCTGACTCTGCCTATTGTTCCTCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCA AATGTGGCCAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCA GCCCCTGCCCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGA TGGACACACAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGC ATGCCCTGCACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAGCTCAGCTGTCCCCAGACCCCATCCCTTCTCCT TTTCCTTTGTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACCAGACCTCATGGGACCAGACCCCTTGGGACCAC ATGGCACAATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAATTACTAATATTATTGAATGCCTTAGAGGAGGC >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000406549_chr22_29706429_+_1180nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGTTC CTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGCCAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAG CCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGCCCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCAC TGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACACAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCG CCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTGCACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAG CTCAGCTGTCCCCAGACCCCATCCCTTCTCCTTTTCCTTTGTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACC AGACCTCATGGGACCAGACCCCTTGGGACCACATGGCACAATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAA TTACTAATATTATTGAATGCCTTAGAGGAGGCCGGGCGAGCCCGGTGTTCTGAAGACCTGTGGCCCAGCAGAGCCTCTGACAGTAAAGTT >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000341313_chr22_29706429_+_1632nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGTG AGATGCAGGAGGACGAGGAGTGAGGGGTCCAGAGGGTGGGGGGGCGTCAGCCCTGGCCTGCATGATGGGTTGCCTGTGCGCCAGAGTGAC TCACACCCTGGGAAAAGTTCCCGTGGGTGGGGGCGGGCCTGGCTTCCCATCTCCATGGCAACCCAACCAAACCAACAACACAGCTGGGGC GGGCCCTGTGGCTGGGCGGCAGCCAGTCCAGCTCTTGCTTCCTCTGGCCCGTCCTGGGAAGGGGGGTGTCTAGAGCCCAGGAAACTTCTT CTTCCGTGGCTTTTGGGGCCCTGGGCCGCTGGAGGAAGCTGCTCACTTCTCCCTGGAAGTCCCCAGGACAGACCGATGCCCCTGACAGCC CCGTCCACCAGCCACATACCCTGCTGTTCCTCTCCCTGCCTGTTCTGCATGCCAGTCCTTCCGTGGTACCCCATCTGTCTCTATTGTCCC CCTGCCCCAGGCCCCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGA GCGGCCCCCTTGGTACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCT CTCCGAGACGGCCTCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCA GCTGTCGGTCCCCAGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCA GCACTCATGGGTGCCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCG GCTTTCCCGGGTCTCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGA GCAGCAGCTGTTCCGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGC >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000403764_chr22_29706429_+_1860nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCC CCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGG TACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCC TCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCC AGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTG CCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTC TCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTC CGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGCCCCTGACCCAGCT CGGGCCCCCGACCCTCCAGCTCCTGACTCTGCCTATTGTTCCTCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGC CAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGC CCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACA CAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTG CACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAGCTCAGCTGTCCCCAGACCCCATCCCTTCTCCTTTTCCTTT GTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACCAGACCTCATGGGACCAGACCCCTTGGGACCACATGGCACA ATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAATTACTAATATTATTGAATGCCTTAGAGGAGGCCGGGCGAG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000407854_chr22_29706429_+_1860nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCC CCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGG TACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCC TCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCC AGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTG CCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTC TCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTC CGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGCCCCTGACCCAGCT CGGGCCCCCGACCCTCCAGCTCCTGACTCTGCCTATTGTTCCTCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGC CAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGC CCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACA CAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTG CACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAGCTCAGCTGTCCCCAGACCCCATCCCTTCTCCTTTTCCTTT GTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACCAGACCTCATGGGACCAGACCCCTTGGGACCACATGGCACA ATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAATTACTAATATTATTGAATGCCTTAGAGGAGGCCGGGCGAG >In-frame_MMP11_ENST00000215743_chr22_24115165_+_GAS2L1_ENST00000471961_chr22_29706429_+_1860nt ATAAGGGGCGGCGGCCCGGAGCGGCCCAGCAAGCCCAGCAGCCCCGGGGCGGATGGCTCCGGCCGCCTGGCTCCGCAGCGCGGCCGCGCG CGCCCTCCTGCCCCCGATGCTGCTGCTGCTGCTCCAGCCGCCGCCGCTGCTGGCCCGGGCTCTGCCGCCGGTGAGGGAGATTCTGGGCCG CTGCACCTGCCCTGACCAGTTTCCCATGATCAAGGTCTCAGAGGGGAAGTACCGTGTGGGGGACTCGAGCCTGCTCATCTTTGTGCGGGT GCTGAGGAGCCACGTGATGGTGCGAGTGGGTGGTGGCTGGGACACGCTGGAGCATTACCTGGACAAGCACGACCCGTGCCGCTGCTCCTC CACTGCTCATCGCCCACCCCAGCCGAGGGTCTGCACCTTTTCTCCACAGAGGGTGTCGCCCACCACCAGTCCCCGCCCTGCTAGCCCAGT CCCTGGGAGTGAGCGCCGGGGCTCCCGGCCTGAGATGACTCCCGTTAGCTTACGAAGCACAAAGGAGGGGCCCGAGACCCCACCCAGGCC CCGGGATCAGCTGCCCCCCCATCCCCGCTCCCGCCGCTACTCCGGGGACAGTGACTCCTCAGCCTCCTCCGCCCAGAGCGGCCCCCTTGG TACCCGCAGTGATGACACAGGCACTGGCCCCCGGAGGGAGCGACCCAGCCGGCGGCTGACCACAGGCACCCCGGCCTCTCCGAGACGGCC TCCTGCCTGCGCAGCCAGTCCCGAGACCGGCTGGATCGCGGCCGGCCCCGGGGGGCCCCAGGAGGCAGGGGAGCCCAGCTGTCGGTCCCC AGCCCTGCCCGGCGGGCCCGGAGCCAGAGCCGCGAGGAGCAGGCTGTGCTGCTTGTGCGCAGGGATCGAGACGGGCAGCACTCATGGGTG CCAAGGGGCAGGGGCAGTGGGGGCTCGGGCAGGAGCACCCCCCAGACTCCCCGTGCCCGCAGCCCTGCAGCACCCCGGCTTTCCCGGGTC TCCAGCCCCAGTCCAGAGTTGGGCACCACACCGGCCAGCATCTTCCGCACACCCCTGCAGCTCGACCCGCAGCAGGAGCAGCAGCTGTTC CGGCGCCTGGAAGAGGAGTTCCTGGCCAATGCCCGGGCCCTTGAGGCTGTTGCTAGCGTGACCCCCACTGGACCAGCCCCTGACCCAGCT CGGGCCCCCGACCCTCCAGCTCCTGACTCTGCCTATTGTTCCTCCAGTTCCTCCTCTTCGTCCCTCAGCGTCCTGGGTGGCAAATGTGGC CAACCTGGGGACTCTGGCCGGACGGCCAATGGGCTGCCTGGGCCCCGAAGCCAAGCCCTTTCCAGCTCCTCCGATGAAGGCAGCCCCTGC CCTGGCATGGGGGGGCCACTAGATGCACCTGGGAGCCCCCTGGCTTGCACTGAACCCTCGAGGACCTGGGCACGGGGTCGGATGGACACA CAGCCAGACCGTAAACCCTCACGTATCCCCACGCCTCGGGGCCCCCGCCGCCCCTCCGGACCCGCAGAGCTGGGGACATGGCATGCCCTG CACTCAGTCACCCCGAGGGCTGAGCCAGATTCCTGGATGTGATGGACCAGCTCAGCTGTCCCCAGACCCCATCCCTTCTCCTTTTCCTTT GTGGCCTTAACCCTTCTGCATCAGGGAGCCCCCTCTGCCTCTTGAGTACCAGACCTCATGGGACCAGACCCCTTGGGACCACATGGCACA ATGGGACCTCTGTTGTACATTCCGGTTGGGGGATGAGCGTTGCTATTTAATTACTAATATTATTGAATGCCTTAGAGGAGGCCGGGCGAG |
Top |
FusionGenePPI for MMP11_GAS2L1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MMP11 | GAS2L1 | SH3KBP1, POT1, MAPRE1, MAPRE3, NXN, SNX5, EPN1, DIS3, USP7, CCNB1, GSN, WDR45B, ZZEF1, RBM12, NAGK, PLCG1, GNB1L, KLHL42, CDKN2C, CAPZA2, PPP1CB, IQGAP1, RTEL1, MYO19, CKS2, LRRFIP1, HECTD3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for MMP11_GAS2L1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for MMP11_GAS2L1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MMP11 | C0000786 | Spontaneous abortion | 1 | CTD_human |
| Hgene | MMP11 | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
| Tgene | GAS2L1 | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
| Tgene | GAS2L1 | C0036341 | Schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|