FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 21943

FusionGeneSummary for MIEF2_RAI1

check button Fusion gene summary
Fusion gene informationFusion gene name: MIEF2_RAI1
Fusion gene ID: 21943
HgeneTgene
Gene symbol

MIEF2

RAI1

Gene ID

125170

10743

Gene namemitochondrial elongation factor 2retinoic acid induced 1
SynonymsMID49|SMCR7SMCR|SMS
Cytomap

17p11.2

17p11.2

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial dynamics protein MID49Smith-Magenis syndrome chromosomal region candidate gene 7 proteinSmith-Magenis syndrome chromosome region, candidate 7mitochondrial dynamic protein MID49mitochondrial dynamic protein of 49 kDamitochondrial dynamicretinoic acid-induced protein 1Smith-Magenis syndrome chromosome region
Modification date2018051920180523
UniProtAcc

Q96C03

Q7Z5J4

Ensembl transtripts involved in fusion geneENST00000323019, ENST00000578174, 
ENST00000395704, ENST00000395703, 
ENST00000577216, ENST00000578621, 
ENST00000395706, 		ENST00000353383, 
ENST00000489697, ENST00000261641, 
Fusion gene scores* DoF score2 X 2 X 1=44 X 4 X 3=48
# samples 14
** MAII scorelog2(1/4*10)=1.32192809488736log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MIEF2 [Title/Abstract] AND RAI1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMIEF2

GO:0007005

mitochondrion organization

21508961

HgeneMIEF2

GO:0032464

positive regulation of protein homooligomerization

23530241

HgeneMIEF2

GO:0090141

positive regulation of mitochondrial fission

23283981|23530241

HgeneMIEF2

GO:0090314

positive regulation of protein targeting to membrane

23283981

HgeneMIEF2

GO:0090314

positive regulation of protein targeting to membrane

23921378

TgeneRAI1

GO:0045893

positive regulation of transcription, DNA-templated

22578325


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-AR-A2LR-01AMIEF2chr17

18168078

+RAI1chr17

17707070

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000323019ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
5CDS-intronENST00000323019ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
5CDS-intronENST00000323019ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-3CDSENST00000578174ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000578174ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000578174ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
3UTR-3CDSENST00000395704ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
3UTR-intronENST00000395704ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
3UTR-intronENST00000395704ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-3CDSENST00000395703ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000395703ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000395703ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-3CDSENST00000577216ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000577216ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000577216ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-3CDSENST00000578621ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000578621ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
intron-intronENST00000578621ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+
In-frameENST00000395706ENST00000353383MIEF2chr17

18168078

+RAI1chr17

17707070

+
5CDS-intronENST00000395706ENST00000489697MIEF2chr17

18168078

+RAI1chr17

17707070

+
5CDS-intronENST00000395706ENST00000261641MIEF2chr17

18168078

+RAI1chr17

17707070

+

Top

FusionProtFeatures for MIEF2_RAI1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MIEF2

Q96C03

RAI1

Q7Z5J4

Mitochondrial outer membrane protein which regulatesmitochondrial fission. Promotes the recruitment and association ofthe fission mediator dynamin-related protein 1 (DNM1L) to themitochondrial surface independently of the mitochondrial fissionFIS1 and MFF proteins. Regulates DNM1L GTPase activity.{ECO:0000269|PubMed:21508961, ECO:0000269|PubMed:23283981,ECO:0000269|PubMed:23530241, ECO:0000269|PubMed:23921378}. Transcriptional regulator of the circadian clockcomponents: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2,NR1D1/2 and RORA/C. Positively regulates the transcriptionalactivity of CLOCK a core component of the circadian clock.Regulates transcription through chromatin remodeling byinteracting with other proteins in chromatin as well as proteinsin the basic transcriptional machinery. May be important forembryonic and postnatal development. May be involved in neuronaldifferentiation. {ECO:0000269|PubMed:22578325}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261855_190318551907Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMIEF2chr17:18168078chr17:17707070ENST00000323019+141_22-71455Topological domainMitochondrial intermembrane
HgeneMIEF2chr17:18168078chr17:17707070ENST00000323019+1444_454-71455Topological domainCytoplasmic
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395704+141_22-50206Topological domainMitochondrial intermembrane
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395704+1444_454-50206Topological domainCytoplasmic
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395706+141_22-9466Topological domainMitochondrial intermembrane
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395706+1444_454-9466Topological domainCytoplasmic
HgeneMIEF2chr17:18168078chr17:17707070ENST00000323019+1423_43-71455TransmembraneHelical
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395704+1423_43-50206TransmembraneHelical
HgeneMIEF2chr17:18168078chr17:17707070ENST00000395706+1423_43-9466TransmembraneHelical
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261243_124918551907Compositional biasNote=Poly-Ser
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+26124_13518551907Compositional biasNote=Poly-Pro
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261493_149618551907Compositional biasNote=Poly-Gly
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+26156_33618551907Compositional biasNote=Gln-rich
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261628_164118551907Compositional biasNote=Ser-rich
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261746_175118551907Compositional biasNote=Poly-Ala
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+26278_29118551907Compositional biasNote=Poly-Gln
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261160_117718551907MotifNuclear localization signal
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261223_124018551907MotifNuclear localization signal
TgeneRAI1chr17:18168078chr17:17707070ENST00000353383+261780_183518551907Zinc fingerC2HC pre-PHD-type


Top

FusionGeneSequence for MIEF2_RAI1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MIEF2_ENST00000323019_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_1103aa
MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRATSPRDEDDTKADSWKELSLLKATPHLQPRPPPAALS
QPVLPLAPSSSAPEGPAETDPEVTPQLSSPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFPELPFGAFVPGG
PLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPA
IGSLLGCLIRPSMASEELLLEVQHERLELTVAVLVAVPGVDADDRLLLAWPLEGLAGNLWLQDLYPVEAARLRALDDHDAGTRRRLLLLL
CAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEP
EGLLXVGGNGWLPCFLMLGSCTHLPSRDLNSGFSLAFCQNKGGYITXTQGIRMCLGYGGHKPXAQRAWVTVTXVQLGCLRQLGVPAIPAS
TVSALGANPRTFGSVHHQQPIHQQNVVSAILGRSXRPASHFCXEKVTXRLFRPXLQAFXGVWCLMVGMVCLFCPPGAGVTWCPXRTDFWL
LKDGIFLLSSVRLVFLLSGSSVXLATHLIPQGKALFPSSQVSVFFRQLRVLGELRLCAAPPAHSWGISLELFQAPLESRGPDPPLERSGV
HSRPPSVPKXTALSXWLYSDFEACXEVARGLEEGDSTSPPKXPSSCLWYPSFXNEAQLRRCEQEXKEKILMYIXLRLDKGVLVLSYAAVE
GFLXVLWLVLALWQECLRSIGGGRVYFKKXHLGRVWWLASVIPAHREAEAGGSRGQEIETILTNMMKPQLYXKDKNXLGVVARTYSPSYS
GGRGRRIAXTREVEVAMSXNCTTALQTGDRARLCLKKINKXASWPRAVAHAYNPSTLGSRGRXITXGWEFKTRLTNVEKLHLWXKFKKIS
WAWWHMPVIPATWEAEAGELLEPGRRRLWXAEIVPVHSSLGNKSETLSQNKIKXNNNSNNKMCSSCQEAGATIGCCHKGCLHTYHYPCAS

>In-frame_MIEF2_ENST00000395706_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_857aa
MGLSPNLDRQTMAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRATSPRDEDDTKADSWKELSLLKATPH
LQPRPPPAALSQPVLPLAPSSSAPEGPAETDPEVTPQLSSPAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFP
ELPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQLEFCPRGSSPWDRFLVGGYLSSRVLLELLR
KALAASVNWPAIGSLLGCLIRPSMASEELLLEVQHERLELTVAVLVAVPGVDADDRLLLAWPLEGLAGNLWLQDLYPVEAARLRALDDHD
AGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALELLIGSLEQASLPCHFNPSVNLFSSLREEEIDDI
GYALYSGLQEPEGLLXVGGNGWLPCFLMLGSCTHLPSRDLNSGFSLAFCQNKGGYITXTQGIRMCLGYGGHKPXAQRAWVTVTXVQLGCL
RQLGVPAIPASTVSALGANPRTFGSVHHQQPIHQQNVVSAILGRSXRPASHFCXEKVTXRLFRPXLQAFXGVWCLMVGMVCLFCPPGAGV
TWCPXRTDFWLLKDGIFLLSSVRLVFLLSGSSVXLATHLIPQGKALFPSSQVSVFFRQLRVLGELRLCAAPPAHSWGISLELFQAPLESR
GPDPPLERSGVHSRPPSVPKXTALSXWLYSDFEACXEVARGLEEGDSTSPPKXPSSCLWYPSFXNEAQLRRCEQEXKEKILMYIXMCSSC


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MIEF2_ENST00000323019_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_3309nt
ATGGCAGAGTTCTCCCAGAAACGGGGGAAGCGGCGTAGCGACGAAGGGCTGGGCAGCATGGTGGACTTCCTCCTGGCCAATGCCCGCCTG
GTGCTGGGCGTGGGCGGGGCTGCTGTGCTGGGCATTGCCACCCTGGCCGTGAAGCGGTTCATTGACAGGGCCACTAGCCCGCGGGATGAG
GATGACACCAAGGCAGACAGCTGGAAGGAACTGAGCCTGCTCAAGGCCACACCACACCTGCAGCCCCGGCCTCCACCTGCTGCCCTTAGC
CAGCCAGTGTTGCCCTTGGCCCCCTCGTCGTCTGCCCCAGAAGGGCCTGCAGAAACTGATCCTGAGGTGACACCACAGCTCAGCTCCCCA
GCACCGCTGTGTCTGACACTGCAGGAGAGGCTGCTGGCCTTCGAGCGGGACCGTGTGACCATCCCAGCAGCCCAGGTGGCTTTGGCCAAA
CAGCTGGCTGGCGACATCGCCCTGGAGCTGCAGGCCTACTTTCGGAGCAAGTTCCCGGAACTGCCCTTTGGGGCATTCGTGCCTGGGGGG
CCGCTCTACGACGGGCTGCAGGCGGGGGCTGCGGACCATGTGCGTCTCCTGGTGCCACTGGTGCTGGAGCCGGGCCTGTGGAGCCTGGTG
CCGGGCGTGGACACTGTGGCGAGGGACCCTCGCTGCTGGGCCGTGCGCAGGACGCAGCTTGAGTTCTGCCCCCGTGGGAGCAGCCCCTGG
GACCGCTTCCTGGTCGGGGGCTACCTCTCCTCCCGCGTCCTGCTGGAGCTACTCCGCAAGGCGCTGGCTGCTTCTGTCAACTGGCCGGCC
ATTGGCAGCCTTCTCGGGTGCCTGATCCGGCCCAGCATGGCCTCGGAGGAGCTGCTGCTCGAGGTGCAGCACGAACGCCTGGAGCTCACT
GTGGCTGTGCTTGTGGCAGTCCCTGGGGTCGATGCTGACGACCGCCTCCTCTTGGCCTGGCCCCTGGAGGGGCTGGCGGGGAACCTCTGG
CTGCAGGACCTGTATCCAGTGGAGGCTGCTAGGCTGCGAGCCCTGGACGACCATGACGCTGGGACTCGCCGGCGGCTGCTGCTGCTGCTG
TGTGCTGTCTGCCGTGGTTGCTCGGCTCTGGGGCAGCTAGGCCGGGGTCACCTGACCCAGGTGGTCCTGCGTCTGGGGGAGGACAACGTG
GATTGGACGGAGGAGGCCTTGGGTGAGCGCTTCCTGCAAGCCCTGGAGCTGCTCATCGGCAGCCTGGAGCAGGCCAGCCTGCCCTGCCAC
TTCAACCCCAGCGTGAACCTCTTCAGCAGCTTGCGTGAGGAGGAGATTGACGACATTGGCTATGCGCTATACAGTGGCCTACAGGAGCCC
GAGGGGCTGCTCTAGGTGGGTGGAAACGGGTGGTTGCCATGTTTTCTAATGCTGGGGAGCTGCACCCACCTCCCTTCCAGGGATTTGAAT
AGTGGTTTTTCTCTAGCTTTTTGCCAGAACAAAGGAGGGTACATTACTTAAACCCAGGGCATCAGGATGTGCTTGGGCTATGGTGGCCAT
AAACCCTGAGCCCAGAGAGCTTGGGTCACTGTCACCTGAGTGCAGCTGGGCTGCCTCAGGCAGCTTGGAGTGCCAGCCATTCCTGCAAGC
ACCGTTTCAGCTCTTGGGGCCAACCCCAGGACCTTTGGCTCTGTCCATCACCAGCAACCAATCCACCAACAGAATGTGGTTTCTGCCATC
CTGGGCAGAAGCTGAAGGCCAGCTTCACATTTCTGCTGAGAGAAGGTGACTTAACGCCTTTTCCGGCCCTAGCTCCAGGCGTTTTGAGGC
GTCTGGTGCCTGATGGTAGGTATGGTGTGTTTGTTCTGTCCCCCAGGGGCTGGAGTCACCTGGTGCCCCTGAAGGACAGATTTTTGGCTG
TTAAAGGATGGCATTTTCCTGCTGTCTTCTGTGCGTTTAGTTTTCTTGCTGAGCGGGAGCTCAGTATGACTTGCCACCCACCTGATACCT
CAGGGCAAGGCCCTTTTTCCCTCCAGCCAGGTGAGTGTTTTCTTCAGGCAGCTGAGGGTCCTGGGGGAGCTGAGGCTCTGTGCTGCACCC
CCAGCCCACAGCTGGGGCATCTCACTGGAGCTGTTCCAGGCCCCACTGGAGAGCAGAGGACCTGATCCCCCACTAGAGAGGTCCGGTGTG
CACAGCCGGCCTCCCAGTGTGCCAAAATGAACTGCTCTCAGCTGATGGCTGTATTCTGACTTTGAAGCCTGTTAAGAGGTAGCAAGGGGG
CTAGAGGAGGGAGATTCCACCTCCCCTCCCAAGTGACCCTCCTCCTGCCTCTGGTATCCTTCCTTTTGAAACGAAGCTCAGCTTCGAAGA
TGTGAACAAGAATAAAAGGAAAAAATTCTAATGTATATATAACTCAGGCTGGATAAGGGAGTCTTGGTGCTTTCATACGCAGCTGTTGAG
GGTTTTCTGTAAGTCCTGTGGCTTGTCCTGGCACTTTGGCAAGAGTGCTTGAGGTCAATTGGAGGTGGTAGAGTTTACTTTAAAAAGTAG
CATCTTGGCCGGGTGTGGTGGCTCGCATCTGTAATCCCAGCACATCGGGAGGCCGAGGCGGGCGGATCACGAGGTCAAGAGATCGAGACC
ATCCTGACCAACATGATGAAACCCCAACTCTACTAAAAAGACAAAAATTAGCTGGGCGTGGTGGCACGCACCTATAGTCCCAGCTACTCG
GGAGGCCGAGGCAGGAGAATTGCTTGAACCCGGGAGGTAGAGGTTGCAATGAGCTGAAATTGCACCACTGCACTCCAGACTGGCGACAGA
GCAAGACTCTGTCTCAAAAAAATAAATAAATAAGCATCTTGGCCCCGCGCTGTGGCTCACGCCTATAATCCCAGCACTTTGGGAAGCCGA
GGCCGGTAGATCACCTGAGGTTGGGAATTCAAGACCAGGCTGACCAACGTGGAGAAACTCCATCTCTGGTAAAAATTCAAAAAAATTAGC
TGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGTGGTGA
GCTGAGATCGTGCCAGTGCACTCCAGCCTAGGCAACAAGAGTGAAACTCTGTCTCAAAATAAAATAAAATAAAATAATAATAGTAATAAT
AAAATGTGTTCCAGCTGCCAAGAAGCCGGGGCCACCATTGGGTGCTGCCACAAAGGATGCCTCCACACCTACCACTACCCGTGTGCCAGC

>In-frame_MIEF2_ENST00000395706_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_2571nt
ATGGGGCTGAGTCCCAATTTAGACAGGCAGACCATGGCAGAGTTCTCCCAGAAACGGGGGAAGCGGCGTAGCGACGAAGGGCTGGGCAGC
ATGGTGGACTTCCTCCTGGCCAATGCCCGCCTGGTGCTGGGCGTGGGCGGGGCTGCTGTGCTGGGCATTGCCACCCTGGCCGTGAAGCGG
TTCATTGACAGGGCCACTAGCCCGCGGGATGAGGATGACACCAAGGCAGACAGCTGGAAGGAACTGAGCCTGCTCAAGGCCACACCACAC
CTGCAGCCCCGGCCTCCACCTGCTGCCCTTAGCCAGCCAGTGTTGCCCTTGGCCCCCTCGTCGTCTGCCCCAGAAGGGCCTGCAGAAACT
GATCCTGAGGTGACACCACAGCTCAGCTCCCCAGCACCGCTGTGTCTGACACTGCAGGAGAGGCTGCTGGCCTTCGAGCGGGACCGTGTG
ACCATCCCAGCAGCCCAGGTGGCTTTGGCCAAACAGCTGGCTGGCGACATCGCCCTGGAGCTGCAGGCCTACTTTCGGAGCAAGTTCCCG
GAACTGCCCTTTGGGGCATTCGTGCCTGGGGGGCCGCTCTACGACGGGCTGCAGGCGGGGGCTGCGGACCATGTGCGTCTCCTGGTGCCA
CTGGTGCTGGAGCCGGGCCTGTGGAGCCTGGTGCCGGGCGTGGACACTGTGGCGAGGGACCCTCGCTGCTGGGCCGTGCGCAGGACGCAG
CTTGAGTTCTGCCCCCGTGGGAGCAGCCCCTGGGACCGCTTCCTGGTCGGGGGCTACCTCTCCTCCCGCGTCCTGCTGGAGCTACTCCGC
AAGGCGCTGGCTGCTTCTGTCAACTGGCCGGCCATTGGCAGCCTTCTCGGGTGCCTGATCCGGCCCAGCATGGCCTCGGAGGAGCTGCTG
CTCGAGGTGCAGCACGAACGCCTGGAGCTCACTGTGGCTGTGCTTGTGGCAGTCCCTGGGGTCGATGCTGACGACCGCCTCCTCTTGGCC
TGGCCCCTGGAGGGGCTGGCGGGGAACCTCTGGCTGCAGGACCTGTATCCAGTGGAGGCTGCTAGGCTGCGAGCCCTGGACGACCATGAC
GCTGGGACTCGCCGGCGGCTGCTGCTGCTGCTGTGTGCTGTCTGCCGTGGTTGCTCGGCTCTGGGGCAGCTAGGCCGGGGTCACCTGACC
CAGGTGGTCCTGCGTCTGGGGGAGGACAACGTGGATTGGACGGAGGAGGCCTTGGGTGAGCGCTTCCTGCAAGCCCTGGAGCTGCTCATC
GGCAGCCTGGAGCAGGCCAGCCTGCCCTGCCACTTCAACCCCAGCGTGAACCTCTTCAGCAGCTTGCGTGAGGAGGAGATTGACGACATT
GGCTATGCGCTATACAGTGGCCTACAGGAGCCCGAGGGGCTGCTCTAGGTGGGTGGAAACGGGTGGTTGCCATGTTTTCTAATGCTGGGG
AGCTGCACCCACCTCCCTTCCAGGGATTTGAATAGTGGTTTTTCTCTAGCTTTTTGCCAGAACAAAGGAGGGTACATTACTTAAACCCAG
GGCATCAGGATGTGCTTGGGCTATGGTGGCCATAAACCCTGAGCCCAGAGAGCTTGGGTCACTGTCACCTGAGTGCAGCTGGGCTGCCTC
AGGCAGCTTGGAGTGCCAGCCATTCCTGCAAGCACCGTTTCAGCTCTTGGGGCCAACCCCAGGACCTTTGGCTCTGTCCATCACCAGCAA
CCAATCCACCAACAGAATGTGGTTTCTGCCATCCTGGGCAGAAGCTGAAGGCCAGCTTCACATTTCTGCTGAGAGAAGGTGACTTAACGC
CTTTTCCGGCCCTAGCTCCAGGCGTTTTGAGGCGTCTGGTGCCTGATGGTAGGTATGGTGTGTTTGTTCTGTCCCCCAGGGGCTGGAGTC
ACCTGGTGCCCCTGAAGGACAGATTTTTGGCTGTTAAAGGATGGCATTTTCCTGCTGTCTTCTGTGCGTTTAGTTTTCTTGCTGAGCGGG
AGCTCAGTATGACTTGCCACCCACCTGATACCTCAGGGCAAGGCCCTTTTTCCCTCCAGCCAGGTGAGTGTTTTCTTCAGGCAGCTGAGG
GTCCTGGGGGAGCTGAGGCTCTGTGCTGCACCCCCAGCCCACAGCTGGGGCATCTCACTGGAGCTGTTCCAGGCCCCACTGGAGAGCAGA
GGACCTGATCCCCCACTAGAGAGGTCCGGTGTGCACAGCCGGCCTCCCAGTGTGCCAAAATGAACTGCTCTCAGCTGATGGCTGTATTCT
GACTTTGAAGCCTGTTAAGAGGTAGCAAGGGGGCTAGAGGAGGGAGATTCCACCTCCCCTCCCAAGTGACCCTCCTCCTGCCTCTGGTAT
CCTTCCTTTTGAAACGAAGCTCAGCTTCGAAGATGTGAACAAGAATAAAAGGAAAAAATTCTAATGTATATATAAATGTGTTCCAGCTGC
CAAGAAGCCGGGGCCACCATTGGGTGCTGCCACAAAGGATGCCTCCACACCTACCACTACCCGTGTGCCAGCGATGCAGGTTGCATATTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MIEF2_ENST00000323019_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_4840nt
CTGAGGCCTGCGCGACCCCGCCAGAGATGGGGCTGAGTCCCAATTTAGACAGGCAGACCATGGCAGAGTTCTCCCAGAAACGGGGGAAGC
GGCGTAGCGACGAAGGGCTGGGCAGCATGGTGGACTTCCTCCTGGCCAATGCCCGCCTGGTGCTGGGCGTGGGCGGGGCTGCTGTGCTGG
GCATTGCCACCCTGGCCGTGAAGCGGTTCATTGACAGGGCCACTAGCCCGCGGGATGAGGATGACACCAAGGCAGACAGCTGGAAGGAAC
TGAGCCTGCTCAAGGCCACACCACACCTGCAGCCCCGGCCTCCACCTGCTGCCCTTAGCCAGCCAGTGTTGCCCTTGGCCCCCTCGTCGT
CTGCCCCAGAAGGGCCTGCAGAAACTGATCCTGAGGTGACACCACAGCTCAGCTCCCCAGCACCGCTGTGTCTGACACTGCAGGAGAGGC
TGCTGGCCTTCGAGCGGGACCGTGTGACCATCCCAGCAGCCCAGGTGGCTTTGGCCAAACAGCTGGCTGGCGACATCGCCCTGGAGCTGC
AGGCCTACTTTCGGAGCAAGTTCCCGGAACTGCCCTTTGGGGCATTCGTGCCTGGGGGGCCGCTCTACGACGGGCTGCAGGCGGGGGCTG
CGGACCATGTGCGTCTCCTGGTGCCACTGGTGCTGGAGCCGGGCCTGTGGAGCCTGGTGCCGGGCGTGGACACTGTGGCGAGGGACCCTC
GCTGCTGGGCCGTGCGCAGGACGCAGCTTGAGTTCTGCCCCCGTGGGAGCAGCCCCTGGGACCGCTTCCTGGTCGGGGGCTACCTCTCCT
CCCGCGTCCTGCTGGAGCTACTCCGCAAGGCGCTGGCTGCTTCTGTCAACTGGCCGGCCATTGGCAGCCTTCTCGGGTGCCTGATCCGGC
CCAGCATGGCCTCGGAGGAGCTGCTGCTCGAGGTGCAGCACGAACGCCTGGAGCTCACTGTGGCTGTGCTTGTGGCAGTCCCTGGGGTCG
ATGCTGACGACCGCCTCCTCTTGGCCTGGCCCCTGGAGGGGCTGGCGGGGAACCTCTGGCTGCAGGACCTGTATCCAGTGGAGGCTGCTA
GGCTGCGAGCCCTGGACGACCATGACGCTGGGACTCGCCGGCGGCTGCTGCTGCTGCTGTGTGCTGTCTGCCGTGGTTGCTCGGCTCTGG
GGCAGCTAGGCCGGGGTCACCTGACCCAGGTGGTCCTGCGTCTGGGGGAGGACAACGTGGATTGGACGGAGGAGGCCTTGGGTGAGCGCT
TCCTGCAAGCCCTGGAGCTGCTCATCGGCAGCCTGGAGCAGGCCAGCCTGCCCTGCCACTTCAACCCCAGCGTGAACCTCTTCAGCAGCT
TGCGTGAGGAGGAGATTGACGACATTGGCTATGCGCTATACAGTGGCCTACAGGAGCCCGAGGGGCTGCTCTAGGTGGGTGGAAACGGGT
GGTTGCCATGTTTTCTAATGCTGGGGAGCTGCACCCACCTCCCTTCCAGGGATTTGAATAGTGGTTTTTCTCTAGCTTTTTGCCAGAACA
AAGGAGGGTACATTACTTAAACCCAGGGCATCAGGATGTGCTTGGGCTATGGTGGCCATAAACCCTGAGCCCAGAGAGCTTGGGTCACTG
TCACCTGAGTGCAGCTGGGCTGCCTCAGGCAGCTTGGAGTGCCAGCCATTCCTGCAAGCACCGTTTCAGCTCTTGGGGCCAACCCCAGGA
CCTTTGGCTCTGTCCATCACCAGCAACCAATCCACCAACAGAATGTGGTTTCTGCCATCCTGGGCAGAAGCTGAAGGCCAGCTTCACATT
TCTGCTGAGAGAAGGTGACTTAACGCCTTTTCCGGCCCTAGCTCCAGGCGTTTTGAGGCGTCTGGTGCCTGATGGTAGGTATGGTGTGTT
TGTTCTGTCCCCCAGGGGCTGGAGTCACCTGGTGCCCCTGAAGGACAGATTTTTGGCTGTTAAAGGATGGCATTTTCCTGCTGTCTTCTG
TGCGTTTAGTTTTCTTGCTGAGCGGGAGCTCAGTATGACTTGCCACCCACCTGATACCTCAGGGCAAGGCCCTTTTTCCCTCCAGCCAGG
TGAGTGTTTTCTTCAGGCAGCTGAGGGTCCTGGGGGAGCTGAGGCTCTGTGCTGCACCCCCAGCCCACAGCTGGGGCATCTCACTGGAGC
TGTTCCAGGCCCCACTGGAGAGCAGAGGACCTGATCCCCCACTAGAGAGGTCCGGTGTGCACAGCCGGCCTCCCAGTGTGCCAAAATGAA
CTGCTCTCAGCTGATGGCTGTATTCTGACTTTGAAGCCTGTTAAGAGGTAGCAAGGGGGCTAGAGGAGGGAGATTCCACCTCCCCTCCCA
AGTGACCCTCCTCCTGCCTCTGGTATCCTTCCTTTTGAAACGAAGCTCAGCTTCGAAGATGTGAACAAGAATAAAAGGAAAAAATTCTAA
TGTATATATAACTCAGGCTGGATAAGGGAGTCTTGGTGCTTTCATACGCAGCTGTTGAGGGTTTTCTGTAAGTCCTGTGGCTTGTCCTGG
CACTTTGGCAAGAGTGCTTGAGGTCAATTGGAGGTGGTAGAGTTTACTTTAAAAAGTAGCATCTTGGCCGGGTGTGGTGGCTCGCATCTG
TAATCCCAGCACATCGGGAGGCCGAGGCGGGCGGATCACGAGGTCAAGAGATCGAGACCATCCTGACCAACATGATGAAACCCCAACTCT
ACTAAAAAGACAAAAATTAGCTGGGCGTGGTGGCACGCACCTATAGTCCCAGCTACTCGGGAGGCCGAGGCAGGAGAATTGCTTGAACCC
GGGAGGTAGAGGTTGCAATGAGCTGAAATTGCACCACTGCACTCCAGACTGGCGACAGAGCAAGACTCTGTCTCAAAAAAATAAATAAAT
AAGCATCTTGGCCCCGCGCTGTGGCTCACGCCTATAATCCCAGCACTTTGGGAAGCCGAGGCCGGTAGATCACCTGAGGTTGGGAATTCA
AGACCAGGCTGACCAACGTGGAGAAACTCCATCTCTGGTAAAAATTCAAAAAAATTAGCTGGGCATGGTGGCACATGCCTGTAATCCCAG
CTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGAGGTTGTGGTGAGCTGAGATCGTGCCAGTGCACTCCAGCCTAG
GCAACAAGAGTGAAACTCTGTCTCAAAATAAAATAAAATAAAATAATAATAGTAATAATAAAATGTGTTCCAGCTGCCAAGAAGCCGGGG
CCACCATTGGGTGCTGCCACAAAGGATGCCTCCACACCTACCACTACCCGTGTGCCAGCGATGCAGGTTGCATATTCATCGAAGAGAACT
TTTCTTTGAAATGTCCCAAACATAAGAGGCTGCCGTAGTAATCCACCCCAACGGCCGGAGGAGCCGCCGGAGCCCGCCTGCCCGCCCGCC
GCCGAAGGAGAGGAGCCGCCTGCGCAGCCCCCGGGCCTTTGAGCTGCTCCCAGCGCTGGTCCAGAGCCGATCCTTGATCCGGGTCCCGGA
TCGTGGATCCGGCCGCCTAGGGCTCAGACTTGCGGCCCCGGGTTGGGAGGAAAACCCGTTCCGGAGCCGCCTGCTCCCGGAACCGGACGG
CACAGGGCGTTCTTGCCCACCCCAGGGGCCAGGCTTGCGGAGGGGGAGCCCGCGGAGCGGCCAGACTCCCCGGGGCGCTCAGCCTCCGGC
GAGGGTGGGAGACGGCTTTGTCCTGGGGACACTTTCCCTCTGGAATCTCAAGACGACGTGGCACACATTCCACGTGGGTGCTGCCGCCAC
CCCAGTCGGTCGTGGCGTGCAGCTGGGAGCCCTGGGCTTGGGGGTGGGGGTCGAAACAGTACTGGAAGAGGCGGAGGGCGGCTCCTAGCT
CCGTGGACTAGGCGGGGGAGAAAGGAAGCCTTTCTGAGAGCGGGCTAGGCCGGCACTGGAGAGGCCGGAGCCTTTGGAACAAACCGTGCG
GAACGCGTCCAGGGGCCTTCCCGCCCAGCCTTTGCCAGATCTCTCGTGCGGTTCGGGCAAAGCCGGGGTAGACCTGGGCTATGCTCAGTT
AGGGGTTGCGGGATCCCCGAGTGTGGGCGGGACTGGGACACCCTTTGGCCTCTGTTTGTCCCCTTTCCAGTCCTCCACCCCACCCCTGGA
GCCCAGCCTGGGAGCGCAAAACCCAAGAAGCGGCCAGAACGCACCTCCGGCTCCGGCGGACGCGCGACCGTTGTGCACCACCAGGGACCG
CCGCGCCTACTCTGCACGGGAGCAGGGACAGCGCTAGATTTCGTGTACAAAACCTGTGTACCCCTCTATATATATGTTACATAGAATGTA
TATATGTTGGGAACATGCTCGCTTCTCCCGTGTGTCGCCGCCGTGCGTCGTGCGCCCGCAACAGAGCCCCAACCGGGCCTTTGCCGGGTA
AGGGGCTACCGCGACGCCACTTGTCCACGCAGCCACCACCGGCCCGGGCCAGTCCCTGCCAGTCCGTCCGCCTGTCCGTCCGTGTCCTCA
GCTCTGTCCACGCTTCGATAGGCCTGACGCAGCCCCCAGCCCAGGGCCGCCCTAGCAACTTCCTGTACATATGACTGTAAAATGGTAAAC
GTGTGTATTATATCTGGCCTCGTTATATAGTGTATATATATGTATACATATACATATATATAATATATATGAAGACTGTAAATGTTAAGA
CGACTAGTGTTCTTATTAGTATATTGCTTCACACTGAAGATTGTGTGTATCGAGCTGTTTCTAAAAGATGTTTATTTTCCTTAAGAGTAA

>In-frame_MIEF2_ENST00000395706_chr17_18168078_+_RAI1_ENST00000353383_chr17_17707070_+_4069nt
CTGAGGCCTGCGCGACCCCGCCAGAGATGGGGCTGAGTCCCAATTTAGACAGGCAGACCATGGCAGAGTTCTCCCAGAAACGGGGGAAGC
GGCGTAGCGACGAAGGGCTGGGCAGCATGGTGGACTTCCTCCTGGCCAATGCCCGCCTGGTGCTGGGCGTGGGCGGGGCTGCTGTGCTGG
GCATTGCCACCCTGGCCGTGAAGCGGTTCATTGACAGGGCCACTAGCCCGCGGGATGAGGATGACACCAAGGCAGACAGCTGGAAGGAAC
TGAGCCTGCTCAAGGCCACACCACACCTGCAGCCCCGGCCTCCACCTGCTGCCCTTAGCCAGCCAGTGTTGCCCTTGGCCCCCTCGTCGT
CTGCCCCAGAAGGGCCTGCAGAAACTGATCCTGAGGTGACACCACAGCTCAGCTCCCCAGCACCGCTGTGTCTGACACTGCAGGAGAGGC
TGCTGGCCTTCGAGCGGGACCGTGTGACCATCCCAGCAGCCCAGGTGGCTTTGGCCAAACAGCTGGCTGGCGACATCGCCCTGGAGCTGC
AGGCCTACTTTCGGAGCAAGTTCCCGGAACTGCCCTTTGGGGCATTCGTGCCTGGGGGGCCGCTCTACGACGGGCTGCAGGCGGGGGCTG
CGGACCATGTGCGTCTCCTGGTGCCACTGGTGCTGGAGCCGGGCCTGTGGAGCCTGGTGCCGGGCGTGGACACTGTGGCGAGGGACCCTC
GCTGCTGGGCCGTGCGCAGGACGCAGCTTGAGTTCTGCCCCCGTGGGAGCAGCCCCTGGGACCGCTTCCTGGTCGGGGGCTACCTCTCCT
CCCGCGTCCTGCTGGAGCTACTCCGCAAGGCGCTGGCTGCTTCTGTCAACTGGCCGGCCATTGGCAGCCTTCTCGGGTGCCTGATCCGGC
CCAGCATGGCCTCGGAGGAGCTGCTGCTCGAGGTGCAGCACGAACGCCTGGAGCTCACTGTGGCTGTGCTTGTGGCAGTCCCTGGGGTCG
ATGCTGACGACCGCCTCCTCTTGGCCTGGCCCCTGGAGGGGCTGGCGGGGAACCTCTGGCTGCAGGACCTGTATCCAGTGGAGGCTGCTA
GGCTGCGAGCCCTGGACGACCATGACGCTGGGACTCGCCGGCGGCTGCTGCTGCTGCTGTGTGCTGTCTGCCGTGGTTGCTCGGCTCTGG
GGCAGCTAGGCCGGGGTCACCTGACCCAGGTGGTCCTGCGTCTGGGGGAGGACAACGTGGATTGGACGGAGGAGGCCTTGGGTGAGCGCT
TCCTGCAAGCCCTGGAGCTGCTCATCGGCAGCCTGGAGCAGGCCAGCCTGCCCTGCCACTTCAACCCCAGCGTGAACCTCTTCAGCAGCT
TGCGTGAGGAGGAGATTGACGACATTGGCTATGCGCTATACAGTGGCCTACAGGAGCCCGAGGGGCTGCTCTAGGTGGGTGGAAACGGGT
GGTTGCCATGTTTTCTAATGCTGGGGAGCTGCACCCACCTCCCTTCCAGGGATTTGAATAGTGGTTTTTCTCTAGCTTTTTGCCAGAACA
AAGGAGGGTACATTACTTAAACCCAGGGCATCAGGATGTGCTTGGGCTATGGTGGCCATAAACCCTGAGCCCAGAGAGCTTGGGTCACTG
TCACCTGAGTGCAGCTGGGCTGCCTCAGGCAGCTTGGAGTGCCAGCCATTCCTGCAAGCACCGTTTCAGCTCTTGGGGCCAACCCCAGGA
CCTTTGGCTCTGTCCATCACCAGCAACCAATCCACCAACAGAATGTGGTTTCTGCCATCCTGGGCAGAAGCTGAAGGCCAGCTTCACATT
TCTGCTGAGAGAAGGTGACTTAACGCCTTTTCCGGCCCTAGCTCCAGGCGTTTTGAGGCGTCTGGTGCCTGATGGTAGGTATGGTGTGTT
TGTTCTGTCCCCCAGGGGCTGGAGTCACCTGGTGCCCCTGAAGGACAGATTTTTGGCTGTTAAAGGATGGCATTTTCCTGCTGTCTTCTG
TGCGTTTAGTTTTCTTGCTGAGCGGGAGCTCAGTATGACTTGCCACCCACCTGATACCTCAGGGCAAGGCCCTTTTTCCCTCCAGCCAGG
TGAGTGTTTTCTTCAGGCAGCTGAGGGTCCTGGGGGAGCTGAGGCTCTGTGCTGCACCCCCAGCCCACAGCTGGGGCATCTCACTGGAGC
TGTTCCAGGCCCCACTGGAGAGCAGAGGACCTGATCCCCCACTAGAGAGGTCCGGTGTGCACAGCCGGCCTCCCAGTGTGCCAAAATGAA
CTGCTCTCAGCTGATGGCTGTATTCTGACTTTGAAGCCTGTTAAGAGGTAGCAAGGGGGCTAGAGGAGGGAGATTCCACCTCCCCTCCCA
AGTGACCCTCCTCCTGCCTCTGGTATCCTTCCTTTTGAAACGAAGCTCAGCTTCGAAGATGTGAACAAGAATAAAAGGAAAAAATTCTAA
TGTATATATAAATGTGTTCCAGCTGCCAAGAAGCCGGGGCCACCATTGGGTGCTGCCACAAAGGATGCCTCCACACCTACCACTACCCGT
GTGCCAGCGATGCAGGTTGCATATTCATCGAAGAGAACTTTTCTTTGAAATGTCCCAAACATAAGAGGCTGCCGTAGTAATCCACCCCAA
CGGCCGGAGGAGCCGCCGGAGCCCGCCTGCCCGCCCGCCGCCGAAGGAGAGGAGCCGCCTGCGCAGCCCCCGGGCCTTTGAGCTGCTCCC
AGCGCTGGTCCAGAGCCGATCCTTGATCCGGGTCCCGGATCGTGGATCCGGCCGCCTAGGGCTCAGACTTGCGGCCCCGGGTTGGGAGGA
AAACCCGTTCCGGAGCCGCCTGCTCCCGGAACCGGACGGCACAGGGCGTTCTTGCCCACCCCAGGGGCCAGGCTTGCGGAGGGGGAGCCC
GCGGAGCGGCCAGACTCCCCGGGGCGCTCAGCCTCCGGCGAGGGTGGGAGACGGCTTTGTCCTGGGGACACTTTCCCTCTGGAATCTCAA
GACGACGTGGCACACATTCCACGTGGGTGCTGCCGCCACCCCAGTCGGTCGTGGCGTGCAGCTGGGAGCCCTGGGCTTGGGGGTGGGGGT
CGAAACAGTACTGGAAGAGGCGGAGGGCGGCTCCTAGCTCCGTGGACTAGGCGGGGGAGAAAGGAAGCCTTTCTGAGAGCGGGCTAGGCC
GGCACTGGAGAGGCCGGAGCCTTTGGAACAAACCGTGCGGAACGCGTCCAGGGGCCTTCCCGCCCAGCCTTTGCCAGATCTCTCGTGCGG
TTCGGGCAAAGCCGGGGTAGACCTGGGCTATGCTCAGTTAGGGGTTGCGGGATCCCCGAGTGTGGGCGGGACTGGGACACCCTTTGGCCT
CTGTTTGTCCCCTTTCCAGTCCTCCACCCCACCCCTGGAGCCCAGCCTGGGAGCGCAAAACCCAAGAAGCGGCCAGAACGCACCTCCGGC
TCCGGCGGACGCGCGACCGTTGTGCACCACCAGGGACCGCCGCGCCTACTCTGCACGGGAGCAGGGACAGCGCTAGATTTCGTGTACAAA
ACCTGTGTACCCCTCTATATATATGTTACATAGAATGTATATATGTTGGGAACATGCTCGCTTCTCCCGTGTGTCGCCGCCGTGCGTCGT
GCGCCCGCAACAGAGCCCCAACCGGGCCTTTGCCGGGTAAGGGGCTACCGCGACGCCACTTGTCCACGCAGCCACCACCGGCCCGGGCCA
GTCCCTGCCAGTCCGTCCGCCTGTCCGTCCGTGTCCTCAGCTCTGTCCACGCTTCGATAGGCCTGACGCAGCCCCCAGCCCAGGGCCGCC
CTAGCAACTTCCTGTACATATGACTGTAAAATGGTAAACGTGTGTATTATATCTGGCCTCGTTATATAGTGTATATATATGTATACATAT
ACATATATATAATATATATGAAGACTGTAAATGTTAAGACGACTAGTGTTCTTATTAGTATATTGCTTCACACTGAAGATTGTGTGTATC
GAGCTGTTTCTAAAAGATGTTTATTTTCCTTAAGAGTAAAAAACAGTCATTGCATTCAGAAAAAAAAAAAAAAAAAAGTCAATAAAGATA


Top

FusionGenePPI for MIEF2_RAI1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MIEF2PSMF1, RABAC1, UBQLN1, UBQLN4, DNM1L, AGTRAPRAI1PIN1, TESC, DDIT3, GATA1, GLI1, LZTR1, MAML3, ZNF496, MAPK8IP2, GSK3B, CASP2, RPS6KA5, CDKN1A, TTR, GADD45A, SIRT7, HECW2, HIST1H2BG, DAXX, TCF20, CDK2AP1, HMG20A, NAGK, NR3C1, AR


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for MIEF2_RAI1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for MIEF2_RAI1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneRAI1C0795864Smith-Magenis syndrome12CTD_human;ORPHANET
TgeneRAI1C0028754Obesity2CTD_human;HPO
TgeneRAI1C0003469Anxiety Disorders1CTD_human
TgeneRAI1C0018273Growth Disorders1CTD_human
TgeneRAI1C0025202melanoma1CTD_human
TgeneRAI1C0036341Schizophrenia1PSYGENET
TgeneRAI1C0376634Craniofacial Abnormalities1CTD_human
TgeneRAI1C0525041Neurobehavioral Manifestations1CTD_human
TgeneRAI1C0700201Dyssomnias1CTD_human
TgeneRAI1C1510586Autism Spectrum Disorders1CTD_human
TgeneRAI1C1970482Potocki-Lupski syndrome1CTD_human
TgeneRAI1C3714756Intellectual Disability1CTD_human;HPO
TgeneRAI1C3887612Psychomotor Agitation1CTD_human