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Fusion gene ID: 21932 |
FusionGeneSummary for MIDN_ABCA7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MIDN_ABCA7 | Fusion gene ID: 21932 | Hgene | Tgene | Gene symbol | MIDN | ABCA7 | Gene ID | 90007 | 10347 |
| Gene name | midnolin | ATP binding cassette subfamily A member 7 | |
| Synonyms | - | ABCA-SSN|ABCX|AD9 | |
| Cytomap | 19p13.3 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | midnolinmidbrain nucleolar protein | ATP-binding cassette sub-family A member 7ATP-binding cassette, sub-family A (ABC1), member 7autoantigen SS-Nmacrophage ABC transporter | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q504T8 | Q8IZY2 | |
| Ensembl transtripts involved in fusion gene | ENST00000300952, ENST00000591446, | ENST00000263094, ENST00000433129, ENST00000435683, ENST00000533574, | |
| Fusion gene scores | * DoF score | 8 X 6 X 5=240 | 5 X 4 X 4=80 |
| # samples | 11 | 5 | |
| ** MAII score | log2(11/240*10)=-1.12553088208386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MIDN [Title/Abstract] AND ABCA7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ABCA7 | GO:0033344 | cholesterol efflux | 14570867 |
| Tgene | ABCA7 | GO:0033700 | phospholipid efflux | 14570867 |
| Tgene | ABCA7 | GO:0034380 | high-density lipoprotein particle assembly | 14570867 |
| Tgene | ABCA7 | GO:0038027 | apolipoprotein A-I-mediated signaling pathway | 14570867 |
| Tgene | ABCA7 | GO:0045332 | phospholipid translocation | 24097981 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LUAD | TCGA-05-4418-01A | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000300952 | ENST00000263094 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| In-frame | ENST00000300952 | ENST00000433129 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| In-frame | ENST00000300952 | ENST00000435683 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| 5CDS-intron | ENST00000300952 | ENST00000533574 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| In-frame | ENST00000591446 | ENST00000263094 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| In-frame | ENST00000591446 | ENST00000433129 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| In-frame | ENST00000591446 | ENST00000435683 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
| 5CDS-intron | ENST00000591446 | ENST00000533574 | MIDN | chr19 | 1251900 | + | ABCA7 | chr19 | 1061781 | + |
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FusionProtFeatures for MIDN_ABCA7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MIDN | ABCA7 |
| Facilitates ubiquitin-independent proteasomaldegradation of polycomb protein CBX4. Plays a role in inhibitingthe activity of glucokinase GCK and both glucose-induced and basalinsulin secretion. {ECO:0000250|UniProtKB:D4AE48,ECO:0000250|UniProtKB:Q3TPJ7}. | Plays a role in phagocytosis by macrophages of apoptoticcells. Binds APOA1 and may function in apolipoprotein-mediatedphospholipid efflux from cells. May also mediate cholesterolefflux. May regulate cellular ceramide homeostasis duringkeratinocytes differentiation. {ECO:0000269|PubMed:12917409,ECO:0000269|PubMed:12925201, ECO:0000269|PubMed:14570867,ECO:0000269|PubMed:14592415}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MIDN | chr19:1251900 | chr19:1061781 | ENST00000300952 | + | 4 | 8 | 31_105 | 128 | 469 | Domain | Ubiquitin-like |
| Hgene | MIDN | chr19:1251900 | chr19:1061781 | ENST00000591446 | + | 3 | 7 | 31_105 | 128 | 469 | Domain | Ubiquitin-like |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1793_2025 | 1683 | 2009 | Domain | ABC transporter 2 |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1827_1834 | 1821 | 2147 | Nucleotide binding | ATP 2 |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1827_1834 | 1821 | 2147 | Nucleotide binding | ATP 2 |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1827_1834 | 1683 | 2009 | Nucleotide binding | ATP 2 |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1683_1703 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | >ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1729_1749 | 1683 | 2009 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1793_2025 | 1821 | 2147 | Domain | ABC transporter 2 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 807_1038 | 1821 | 2147 | Domain | ABC transporter 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1793_2025 | 1821 | 2147 | Domain | ABC transporter 2 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 807_1038 | 1821 | 2147 | Domain | ABC transporter 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 807_1038 | 1683 | 2009 | Domain | ABC transporter 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 841_848 | 1821 | 2147 | Nucleotide binding | ATP 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 841_848 | 1821 | 2147 | Nucleotide binding | ATP 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 841_848 | 1683 | 2009 | Nucleotide binding | ATP 1 |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1264_1537 | 1821 | 2147 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 43_549 | 1821 | 2147 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1264_1537 | 1821 | 2147 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 43_549 | 1821 | 2147 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1264_1537 | 1683 | 2009 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 43_549 | 1683 | 2009 | Topological domain | Extracellular |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1243_1263 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1538_1558 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1584_1604 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1621_1641 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1649_1669 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1683_1703 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 1729_1749 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 22_42 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 550_570 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 593_613 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 626_646 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 655_675 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 687_707 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 727_747 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000263094 | + | 39 | 47 | 849_869 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1243_1263 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1538_1558 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1584_1604 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1621_1641 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1649_1669 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1683_1703 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 1729_1749 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 22_42 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 550_570 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 593_613 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 626_646 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 655_675 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 687_707 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 727_747 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000433129 | + | 38 | 46 | 849_869 | 1821 | 2147 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1243_1263 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1538_1558 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1584_1604 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1621_1641 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 1649_1669 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 22_42 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 550_570 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 593_613 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 626_646 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 655_675 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 687_707 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 727_747 | 1683 | 2009 | Transmembrane | Helical |
| Tgene | ABCA7 | chr19:1251900 | chr19:1061781 | ENST00000435683 | + | 33 | 41 | 849_869 | 1683 | 2009 | Transmembrane | Helical |
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FusionGeneSequence for MIDN_ABCA7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_454aa MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGV GDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQCFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSMGYCP QSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRF LWNSLLAVVREGRSVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFPGAELREAHGG RLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_1362nt ATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCC ATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTG TCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTG GGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCT CTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGAC ACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCT CAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCC CAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAG CTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTC CTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCG CGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACC CTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGC CGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTG GAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAG AAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_2021nt GATAAAGGCTGAGGGCCGCGCGCTTGGCCCAGACCGGCCCGGCCAGCGCGCATTCGGCCCCGGACGAAGGTACTCGCAGCACTTGGAGCG CAGAACCGGCCGCGCCCGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGAC GGCACCCAGCGCCACCAGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAG AAGCAAGTGCCGTCCCCACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCAT TCCGCGGCCGGGACTTTCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCC TGTCCCGGAGGCGCGGCGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCC GGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCA CGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGG AGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGG TACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGT GTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTG TGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGC TGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGC GTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTG GGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGG TGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGC GGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCC AGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGG GAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGA TGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACC CCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAGACTGTGCTCTGAGCCTCCCTCCCCT GCGGGGCCGCGGGGAGGCCCTGGGAATGGCAAGGGCAAGGTAGAGTGCCTAGGAGCCCTGGACTCAGGCTGGCAGAGGGGCTGGTGCCCT >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_2021nt GATAAAGGCTGAGGGCCGCGCGCTTGGCCCAGACCGGCCCGGCCAGCGCGCATTCGGCCCCGGACGAAGGTACTCGCAGCACTTGGAGCG CAGAACCGGCCGCGCCCGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGAC GGCACCCAGCGCCACCAGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAG AAGCAAGTGCCGTCCCCACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCAT TCCGCGGCCGGGACTTTCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCC TGTCCCGGAGGCGCGGCGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCC GGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCA CGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGG AGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGG TACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGT GTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTG TGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGC TGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGC GTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTG GGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGG TGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGC GGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCC AGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGG GAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGA TGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACC CCGCGCCAGGCCTGCAGCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAGACTGTGCTCTGAGCCTCCCTCCCCT GCGGGGCCGCGGGGAGGCCCTGGGAATGGCAAGGGCAAGGTAGAGTGCCTAGGAGCCCTGGACTCAGGCTGGCAGAGGGGCTGGTGCCCT >In-frame_MIDN_ENST00000300952_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_1877nt GATAAAGGCTGAGGGCCGCGCGCTTGGCCCAGACCGGCCCGGCCAGCGCGCATTCGGCCCCGGACGAAGGTACTCGCAGCACTTGGAGCG CAGAACCGGCCGCGCCCGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGAC GGCACCCAGCGCCACCAGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAG AAGCAAGTGCCGTCCCCACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCAT TCCGCGGCCGGGACTTTCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCC TGTCCCGGAGGCGCGGCGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCC GGAGCTGCCGGCGCGGGGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCA CGGGCACCCGCTACGACCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGG AGCGCCTGGCTCTTCTCCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGG TACCCACCGTGGAAGCGGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGT GTTTTGGGCTGCTGGGTGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTG TGCTGGCAGGCCACAGCGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGC TGACGGGCCGCGAGCACCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGC GTCTGGGACTCTCATGGTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTG GGGACCCAGCCGTGGTGTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGG TGCGGGAGGGCCGTTCAGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGC GGTTCCGCTGCCTGGGCAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCC AGCCGGCAGCGGCCTTCGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGG GAGGGCGCTGCGCCCTGGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGA TGCTGGAGGAGGTATTCTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACC >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000263094_chr19_1061781_+_1915nt AGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGACGGCACCCAGCGCCACC AGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAGAAGCAAGTGCCGTCCC CACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCATTCCGCGGCCGGGACTT TCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCCTGTCCCGGAGGCGCGG CGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGG GGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGA CCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCT CCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGC GGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGG TGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAG CGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCA CCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATG GTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGT GTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTC AGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGG CAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTT CGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCT GGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATT CTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCA GCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAGACTGTGCTCTGAGCCTCCCTCCCCTGCGGGGCCGCGGGGAG GCCCTGGGAATGGCAAGGGCAAGGTAGAGTGCCTAGGAGCCCTGGACTCAGGCTGGCAGAGGGGCTGGTGCCCTGGAGAAAATAAAGAGA >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000433129_chr19_1061781_+_1915nt AGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGACGGCACCCAGCGCCACC AGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAGAAGCAAGTGCCGTCCC CACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCATTCCGCGGCCGGGACTT TCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCCTGTCCCGGAGGCGCGG CGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGG GGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGA CCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCT CCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGC GGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGG TGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAG CGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCA CCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATG GTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGT GTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTC AGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGG CAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTT CGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCT GGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATT CTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCA GCACCCCAAACGCGTCAGCCAGTTCCTCGATGACCCTAGCACTGCCGAGACTGTGCTCTGAGCCTCCCTCCCCTGCGGGGCCGCGGGGAG GCCCTGGGAATGGCAAGGGCAAGGTAGAGTGCCTAGGAGCCCTGGACTCAGGCTGGCAGAGGGGCTGGTGCCCTGGAGAAAATAAAGAGA >In-frame_MIDN_ENST00000591446_chr19_1251900_+_ABCA7_ENST00000435683_chr19_1061781_+_1771nt AGATCCTCCGAGCGGCGGCGACGGCTGTTGCTAAGGGAGGGGACGCGCGAGGAAGCGCGACCCGGGCGGCAGACGGCACCCAGCGCCACC AGCCGAGCGGCGCCCCCTCCCCAGGACCCTTAACCGCGCCGCGTCCCGGTCGCGCCCGCCGCCCTTTGAAGGAGAAGCAAGTGCCGTCCC CACCCCCGGAAGGCGCCCCCAGGAGCCGGAGCGACCTCGGAGCGCCACTCGGATTTTGGATTTCGGTCTCGCATTCCGCGGCCGGGACTT TCTCGAGGAGGACGCGCGCTGCTCCGCGCCCCCGAGTGCCCGGAGGACCCGGCATCCGGGGAGCCTCTCGCCCCTGTCCCGGAGGCGCGG CGAGGATTGGCGGCGCCCGCCGCCCCCAGCCCCCCAGCGCGCGCCGGGGATGGAGCCGCAGCCCGGCGGCGCCCGGAGCTGCCGGCGCGG GGCCCCCGGCGGCGCCTGCGAGCTGGGCCCGGCGGCCGAGGCGGCGCCCATGAGCCTCGCCATCCACAGCACCACGGGCACCCGCTACGA CCTGGCCGTGCCGCCCGACGAGACGGTGGAGGGGCTGCGCAAGCGGTTGTCCCAGCGCCTCAAAGTGCCCAAGGAGCGCCTGGCTCTTCT CCACAAAGACACCCGGCTCAGTTCGGGGAAGCTGCAGGAGTTCGGCGTGGGTGATGGCAGCAAGCTGACCTTGGTACCCACCGTGGAAGC GGGCCTCATGTCTCAGGCCTCAAGGCCGGAACAGTCCGTGATGCAAGCTCTCGAGAGTCTCACGGAGACGCAGTGTTTTGGGCTGCTGGG TGTGAATGGAGCAGGGAAGACGTCCACGTTTCGCATGGTGACGGGGGACACATTGGCCAGCAGGGGCGAGGCTGTGCTGGCAGGCCACAG CGTGGCCCGGGAACCCAGTGCTGCGCACCTCAGCATGGGATACTGCCCTCAATCCGATGCCATCTTTGAGCTGCTGACGGGCCGCGAGCA CCTGGAGCTGCTTGCGCGCCTGCGCGGTGTCCCGGAGGCCCAGGTTGCCCAGACCGCTGGCTCGGGCCTGGCGCGTCTGGGACTCTCATG GTACGCAGACCGGCCTGCAGGCACCTACAGCGGAGGGAACAAACGCAAGCTGGCGACGGCCCTGGCGCTGGTTGGGGACCCAGCCGTGGT GTTTCTGGACGAGCCGACCACAGGCATGGACCCCAGCGCGCGGCGCTTCCTTTGGAACAGCCTTTTGGCCGTGGTGCGGGAGGGCCGTTC AGTGATGCTCACCTCCCATAGCATGGAGGAGTGTGAAGCGCTCTGCTCGCGCCTGGCCATCATGGTGAATGGGCGGTTCCGCTGCCTGGG CAGCCCGCAACATCTCAAGGGCAGATTCGCGGCGGGTCACACACTGACCCTGCGGGTGCCCGCCGCAAGGTCCCAGCCGGCAGCGGCCTT CGTGGCGGCCGAGTTCCCTGGGGCGGAGCTGCGCGAGGCACATGGAGGCCGCCTGCGCTTCCAGCTGCCGCCGGGAGGGCGCTGCGCCCT GGCGCGCGTCTTTGGAGAGCTGGCGGTGCACGGCGCAGAGCACGGCGTGGAGGACTTTTCCGTGAGCCAGACGATGCTGGAGGAGGTATT CTTGTACTTCTCCAAGGACCAGGGGAAGGACGAGGACACCGAAGAGCAGAAGGAGGCAGGAGTGGGAGTGGACCCCGCGCCAGGCCTGCA |
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FusionGenePPI for MIDN_ABCA7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MIDN | GADD45G, GADD45A, ZAK, ELAVL1, PSMC1, EGR1, NR4A1, ERCC6L | ABCA7 | HNRNPD, LLGL2, SORT1, SYNCRIP, SGTB, HTR3A, GABRA3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MIDN_ABCA7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MIDN_ABCA7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ABCA7 | C0002395 | Alzheimer's Disease | 2 | CTD_human |
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