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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 21802

FusionGeneSummary for MGAT5B_VMP1

check button Fusion gene summary
Fusion gene informationFusion gene name: MGAT5B_VMP1
Fusion gene ID: 21802
HgeneTgene
Gene symbol

MGAT5B

VMP1

Gene ID

146664

81671

Gene namemannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme Bvacuole membrane protein 1
SynonymsGnT-IX|GnT-VBEPG3|TANGO5|TMEM49
Cytomap

17q25.2

17q23.1

Type of geneprotein-codingprotein-coding
Descriptionalpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase BN-acetylglucosaminyl-transferase VbN-acetylglucosaminyltransferase IXalpha-mannoside beta-1,6-N-acetylglucosaminyltransferase Bbeta(1,6)-N-acetylglucosaminyltransferase VglcNAc-T vacuole membrane protein 1ectopic P-granules autophagy protein 3 homologtransmembrane protein 49transport and golgi organization 5 homolog
Modification date2018052320180523
UniProtAcc

Q3V5L5

Q96GC9

Ensembl transtripts involved in fusion geneENST00000569840, ENST00000301618, 
ENST00000565675, ENST00000374998, 
ENST00000428789, 
ENST00000262291, 
ENST00000537567, ENST00000539763, 
ENST00000536180, ENST00000545362, 
ENST00000588617, 
Fusion gene scores* DoF score3 X 2 X 3=1824 X 11 X 12=3168
# samples 327
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(27/3168*10)=-3.55254102302878
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MGAT5B [Title/Abstract] AND VMP1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDKIRCTCGA-BP-4983-01AMGAT5Bchr17

74878380

+VMP1chr17

57842332

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000569840ENST00000262291MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
Frame-shitENST00000569840ENST00000537567MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000569840ENST00000539763MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000569840ENST00000536180MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000569840ENST00000545362MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000569840ENST00000588617MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
Frame-shitENST00000301618ENST00000262291MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
Frame-shitENST00000301618ENST00000537567MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000301618ENST00000539763MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000301618ENST00000536180MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000301618ENST00000545362MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000301618ENST00000588617MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
In-frameENST00000565675ENST00000262291MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
In-frameENST00000565675ENST00000537567MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000565675ENST00000539763MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000565675ENST00000536180MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000565675ENST00000545362MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000565675ENST00000588617MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-3CDSENST00000374998ENST00000262291MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-3CDSENST00000374998ENST00000537567MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-5UTRENST00000374998ENST00000539763MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-5UTRENST00000374998ENST00000536180MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-intronENST00000374998ENST00000545362MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
3UTR-intronENST00000374998ENST00000588617MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
Frame-shitENST00000428789ENST00000262291MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
Frame-shitENST00000428789ENST00000537567MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000428789ENST00000539763MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-5UTRENST00000428789ENST00000536180MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000428789ENST00000545362MGAT5Bchr17

74878380

+VMP1chr17

57842332

+
5CDS-intronENST00000428789ENST00000588617MGAT5Bchr17

74878380

+VMP1chr17

57842332

+

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FusionProtFeatures for MGAT5B_VMP1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MGAT5B

Q3V5L5

VMP1

Q96GC9

Glycosyltransferase that acts on alpha-linked mannose ofN-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannoseresidue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- andalpha1,6-linked mannose arms in the core structure of N-glycan.Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a2,6-branched structure in brain O-mannosyl glycan. Plays an activerole in modulating integrin and laminin-dependent adhesion andmigration of neuronal cells via its activity in the O-mannosylglycan pathway. {ECO:0000269|PubMed:12941944,ECO:0000269|PubMed:14617637, ECO:0000269|PubMed:14623122,ECO:0000269|PubMed:16606368, ECO:0000269|PubMed:16857188}. Stress-induced protein that, when overexpressed,promotes formation of intracellular vacuoles followed by celldeath. May be involved in the cytoplasmic vacuolization of acinarcells during the early stage of acute pancreatitis. Plays a rolein the initial stages of the autophagic process through itsinteraction with BECN1 (By similarity). Involved in cell-celladhesion. Plays an essential role in formation of cell junctions.{ECO:0000250, ECO:0000269|PubMed:17724469}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for MGAT5B_VMP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000262291_chr17_57842332_+_455aa
MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALAR
LENSSELHRAGGDLHFPADR_GDVGRRHTEQGSGGTCHSIRGAVRHLLL_IWRRFGPHCGTAQSAFLPPKFNNR_HLVTFVACFPL_IKR
HR_KLKGPHIASVTLAATECNSVNFPEPPTPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPTFMARAARLSGAEPDDE
ETQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITF
SKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSTAKRIQQRLNSE

>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000537567_chr17_57842332_+_455aa
MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALAR
LENSSELHRAGGDLHFPADR_GDVGRRHTEQGSGGTCHSIRGAVRHLLL_IWRRFGPHCGTAQSAFLPPKFNNR_HLVTFVACFPL_IKR
HR_KLKGPHIASVTLAATECNSVNFPEPPTPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPTFMARAARLSGAEPDDE
ETQEFEEMLEHAESAQDFASRAKLAVQKLVQKVGFFGILACASIPNPLFDLAGITCGHFLVPFWTFFGATLIGKAIIKMHIQKIFVIITF
SKHIVEQMVAFIGAVPGIGPSLQKPFQEYLEAQRQKLHHKSEMGTPQGENWLSWMFEKLVVVMVCYFILSIINSMAQSTAKRIQQRLNSE


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000262291_chr17_57842332_+_1365nt
ATGATCACCGTCAACCCCGATGGGAAGATAATGGTCAGAAGATGCCTGGTCACCCTGAGACCCTTTCGGCTTTTTGTCCTGGGCATCGGC
TTCTTCACTCTCTGCTTCCTGATGACGTCTCTGGGAGGCCAGTTCTCGGCCCGGCGCCTGGGGGACTCGCCATTCACCATCCGCACAGAA
GTGATGGGGGGCCCCGAGTCCCGCGGCGTCCTGCGCAAGATGAGCGACCTGCTGGAGCTGATGGTGAAGCGCATGGACGCACTGGCCAGG
CTGGAGAACAGCAGTGAGCTGCACCGGGCCGGCGGCGACCTGCACTTTCCCGCAGACAGGTGAGGGGACGTGGGGAGGAGGCACACGGAG
CAGGGGAGCGGTGGCACCTGCCACTCCATCCGGGGTGCTGTCCGTCATCTCCTTTTGTGAATCTGGAGAAGATTTGGACCACACTGTGGT
ACAGCCCAGAGTGCATTTCTACCACCCAAATTTAACAACCGTTAACATTTGGTCACATTTGTGGCCTGTTTTCCTCTTTAAATAAAACGT
CACAGATGAAAACTAAAAGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTAT
CCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGC
ATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAA
GAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTA
CAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTG
GTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTC
AGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTG
GAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTC
GTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAG

>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000537567_chr17_57842332_+_1365nt
ATGATCACCGTCAACCCCGATGGGAAGATAATGGTCAGAAGATGCCTGGTCACCCTGAGACCCTTTCGGCTTTTTGTCCTGGGCATCGGC
TTCTTCACTCTCTGCTTCCTGATGACGTCTCTGGGAGGCCAGTTCTCGGCCCGGCGCCTGGGGGACTCGCCATTCACCATCCGCACAGAA
GTGATGGGGGGCCCCGAGTCCCGCGGCGTCCTGCGCAAGATGAGCGACCTGCTGGAGCTGATGGTGAAGCGCATGGACGCACTGGCCAGG
CTGGAGAACAGCAGTGAGCTGCACCGGGCCGGCGGCGACCTGCACTTTCCCGCAGACAGGTGAGGGGACGTGGGGAGGAGGCACACGGAG
CAGGGGAGCGGTGGCACCTGCCACTCCATCCGGGGTGCTGTCCGTCATCTCCTTTTGTGAATCTGGAGAAGATTTGGACCACACTGTGGT
ACAGCCCAGAGTGCATTTCTACCACCCAAATTTAACAACCGTTAACATTTGGTCACATTTGTGGCCTGTTTTCCTCTTTAAATAAAACGT
CACAGATGAAAACTAAAAGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTAT
CCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGC
ATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAA
GAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTA
CAGAAAGTTGGATTTTTTGGAATTTTGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTG
GTACCTTTTTGGACCTTCTTTGGTGCAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTC
AGCAAGCACATAGTGGAGCAAATGGTGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTG
GAGGCTCAACGGCAGAAGCTTCACCACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTC
GTTGTCATGGTGTGTTACTTCATCCTATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000262291_chr17_57842332_+_2791nt
TCAATTCAACAAATGTCTATTGACTACTTTCTGCGCGGTGGTTGCTGTGGATTCAGAAATTAATTAGATGTGATCCCTGGCTTAAGGGTG
TCACAGCCCGATAGGAGAAAACAGACATGAATAATCTTAGAAGGATCTAGTAAGTTCTCAGCTTGGAGGTGTATACAAGGTGTTGCTGGA
AGGAAGTGAAGGAGCAGTTAAGTCTGCCCTGGAGTACAATGGGAGATATATTGGTAAAAGCCACAGAGAAGAGCTGAGTTCCAGGATCAA
GCCAGGAAGGAATAAGTCTCACGTCAAGGCTTTAAATATCTCGGCTTTTTGTCCTGGGCATCGGCTTCTTCACTCTCTGCTTCCTGATGA
CGTCTCTGGGAGGCCAGTTCTCGGCCCGGCGCCTGGGGGACTCGCCATTCACCATCCGCACAGAAGTGATGGGGGGCCCCGAGTCCCGCG
GCGTCCTGCGCAAGATGAGCGACCTGCTGGAGCTGATGGTGAAGCGCATGGACGCACTGGCCAGGCTGGAGAACAGCAGTGAGCTGCACC
GGGCCGGCGGCGACCTGCACTTTCCCGCAGACAGGTGAGGGGACGTGGGGAGGAGGCACACGGAGCAGGGGAGCGGTGGCACCTGCCACT
CCATCCGGGGTGCTGTCCGTCATCTCCTTTTGTGAATCTGGAGAAGATTTGGACCACACTGTGGTACAGCCCAGAGTGCATTTCTACCAC
CCAAATTTAACAACCGTTAACATTTGGTCACATTTGTGGCCTGTTTTCCTCTTTAAATAAAACGTCACAGATGAAAACTAAAAGGTCCAC
ATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATG
AAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCG
GAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGC
TGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTT
TGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTG
CAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGG
TGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACC
ACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCC
TATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAG
TTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTA
TCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCAC
CCTCGATGCAATCCACCTTGTGTTTTCTTAGGGTGGAATGTGATGTTCAGCAGCAAACTTGCAACAGACTGGCCTTCTGTTTGTTACTTT
CAAAAGGCCCACATGATACAATTAGAGAATTCCCACCGCACAAAAAAAGTTCCTAAGTATGTTAAATATGTCAAGCTTTTTAGGCTTGTC
ACAAATGATTGCTTTGTTTTCCTAAGTCATCAAAATGTATATAAATTATCTAGATTGGATAACAGTCTTGCATGTTTATCATGTTACAAT
TTAATATTCCATCCTGCCCAACCCTTCCTCTCCCATCCTCAAAAAAGGGCCATTTTATGATGCATTGCACACCCTCTGGGGAAATTGATC
TTTAAATTTTGAGACAGTATAAGGAAAATCTGGTTGGTGTCTTACAAGTGAGCTGACACCATTTTTTATTCTGTGTATTTAGAATGAAGT
CTTGAAAAAAACTTTATAAAGACATCTTTAATCATTCCAAAATTGTGTCCGTTTTCTTGAGCGTTTTGATTTTTTACTTTTAGCTTATAC
CAGCTGAATGGCAGCCTTGCCTAATCCACCTACAACAAGAATTTCTTAAGCTTTCTTTTATTTGCATGAGAGAGCCACTACCAAGGCATG
TTTTGTTATGCTGAAACTGGGCTGCTGCATACTGCTAAATGGCACCTCTGGGATTGGCCTACCTGGGGATTTCTTGGTTTGTGAAAACAG
GAGAGGAGAAATATCTCATACAAGTGAAAGGATACTGGAGAGAGAAATTACCCATTTCTAAAAAAAAACCACACTCTGTCGTATCTGTGT
TAATGTTTTCTAGCATGTACTCTGGTTTCAACAGACACAAATTTATATGTTAACCCAGTTTTCTTGCCGTTCTGTAAGTGTTTTATTCTT
AGTGTGATTTTTTTCCATTGGGATGTTTTTGATTGAACTTGTTCATTTTGTTTTGCTTGGGAGGAAAATAAACAATTTTACTTTTTTCCT

>In-frame_MGAT5B_ENST00000565675_chr17_74878380_+_VMP1_ENST00000537567_chr17_57842332_+_1870nt
TCAATTCAACAAATGTCTATTGACTACTTTCTGCGCGGTGGTTGCTGTGGATTCAGAAATTAATTAGATGTGATCCCTGGCTTAAGGGTG
TCACAGCCCGATAGGAGAAAACAGACATGAATAATCTTAGAAGGATCTAGTAAGTTCTCAGCTTGGAGGTGTATACAAGGTGTTGCTGGA
AGGAAGTGAAGGAGCAGTTAAGTCTGCCCTGGAGTACAATGGGAGATATATTGGTAAAAGCCACAGAGAAGAGCTGAGTTCCAGGATCAA
GCCAGGAAGGAATAAGTCTCACGTCAAGGCTTTAAATATCTCGGCTTTTTGTCCTGGGCATCGGCTTCTTCACTCTCTGCTTCCTGATGA
CGTCTCTGGGAGGCCAGTTCTCGGCCCGGCGCCTGGGGGACTCGCCATTCACCATCCGCACAGAAGTGATGGGGGGCCCCGAGTCCCGCG
GCGTCCTGCGCAAGATGAGCGACCTGCTGGAGCTGATGGTGAAGCGCATGGACGCACTGGCCAGGCTGGAGAACAGCAGTGAGCTGCACC
GGGCCGGCGGCGACCTGCACTTTCCCGCAGACAGGTGAGGGGACGTGGGGAGGAGGCACACGGAGCAGGGGAGCGGTGGCACCTGCCACT
CCATCCGGGGTGCTGTCCGTCATCTCCTTTTGTGAATCTGGAGAAGATTTGGACCACACTGTGGTACAGCCCAGAGTGCATTTCTACCAC
CCAAATTTAACAACCGTTAACATTTGGTCACATTTGTGGCCTGTTTTCCTCTTTAAATAAAACGTCACAGATGAAAACTAAAAGGTCCAC
ATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATG
AAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCG
GAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGC
TGGAACATGCAGAGTCTGCACAAGACTTTGCCTCCCGGGCCAAACTGGCAGTTCAAAAACTAGTACAGAAAGTTGGATTTTTTGGAATTT
TGGCCTGTGCTTCAATTCCAAATCCTTTATTTGATCTGGCTGGAATAACGTGTGGACACTTTCTGGTACCTTTTTGGACCTTCTTTGGTG
CAACCCTAATTGGAAAAGCAATAATAAAAATGCATATCCAGAAAATTTTTGTTATAATAACATTCAGCAAGCACATAGTGGAGCAAATGG
TGGCTTTCATTGGTGCTGTCCCCGGCATAGGTCCATCTCTGCAGAAGCCATTTCAGGAGTACCTGGAGGCTCAACGGCAGAAGCTTCACC
ACAAAAGCGAAATGGGCACACCACAGGGAGAAAACTGGTTGTCCTGGATGTTTGAAAAGTTGGTCGTTGTCATGGTGTGTTACTTCATCC
TATCTATCATTAACTCCATGGCACAAAGTTATGCCAAACGAATCCAGCAGCGGTTGAACTCAGAGGAGAAAACTAAATAAGTAGAGAAAG
TTTTAAACTGCAGAAATTGGAGTGGATGGGTTCTGCCTTAAATTGGGAGGACTCCAAGCCGGGAAGGAAAATTCCCTTTTCCAACCTGTA
TCAATTTTTACAACTTTTTTCCTGAAAGCAGTTTAGTCCATACTTTGCACTGACATACTTTTTCCTTCTGTGCTAAGGTAAGGTATCCAC


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FusionGenePPI for MGAT5B_VMP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MGAT5BPITX1, CAMK2B, HOXA1, MDFI, OTX1, PLSCR1, PTGER3, STK16, TRIP13, CREB5, RBPMS, VAC14, EIF4ENIF1, DMRT3, C20orf195, TXNDC5, FAM83A, KRTAP19-5, KLHL38, KRTAP12-2, KRTAP26-1, C4orf29VMP1HGS, ELAVL1, TJP1, KLK11, LPAR6, ERGIC3, FAF2, KRAS, TCTN2, TCTN3, TMEM216, DPEP1, CDH13, MAS1, LMNA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MGAT5B_VMP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MGAT5B_VMP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneMGAT5BC0032460Polycystic Ovary Syndrome1CTD_human