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Fusion gene ID: 21713 |
FusionGeneSummary for METTL25_PTPRQ |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: METTL25_PTPRQ | Fusion gene ID: 21713 | Hgene | Tgene | Gene symbol | METTL25 | PTPRQ | Gene ID | 84190 | 374462 |
| Gene name | methyltransferase like 25 | protein tyrosine phosphatase, receptor type Q | |
| Synonyms | C12orf26 | DFNA73|DFNB84|DFNB84A|PTPGMC1|R-PTP-Q | |
| Cytomap | 12q21.31 | 12q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | methyltransferase-like protein 25 | phosphatidylinositol phosphatase PTPRQphosphotidylinositol phosphatase PTPRQprotein-tyrosine phosphatase, receptor-type, expressed by glomerular mesangial cells | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8N6Q8 | Q9UMZ3 | |
| Ensembl transtripts involved in fusion gene | ENST00000248306, ENST00000547357, | ENST00000266688, ENST00000547485, | |
| Fusion gene scores | * DoF score | 5 X 4 X 1=20 | 8 X 6 X 4=192 |
| # samples | 5 | 6 | |
| ** MAII score | log2(5/20*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/192*10)=-1.67807190511264 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: METTL25 [Title/Abstract] AND PTPRQ [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PTPRQ | GO:0045598 | regulation of fat cell differentiation | 19351528 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-AB35-01A | METTL25 | chr12 | 82796909 | + | PTPRQ | chr12 | 81025971 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000248306 | ENST00000266688 | METTL25 | chr12 | 82796909 | + | PTPRQ | chr12 | 81025971 | + |
| 5CDS-intron | ENST00000248306 | ENST00000547485 | METTL25 | chr12 | 82796909 | + | PTPRQ | chr12 | 81025971 | + |
| 3UTR-3CDS | ENST00000547357 | ENST00000266688 | METTL25 | chr12 | 82796909 | + | PTPRQ | chr12 | 81025971 | + |
| 3UTR-intron | ENST00000547357 | ENST00000547485 | METTL25 | chr12 | 82796909 | + | PTPRQ | chr12 | 81025971 | + |
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FusionProtFeatures for METTL25_PTPRQ |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| METTL25 | PTPRQ |
| Putative methyltransferase. {ECO:0000250}. | Phosphatidylinositol phosphatase required for auditoryfunction. May act by regulating the level of phosphatidylinositol4,5-bisphosphate (PIP2) level in the basal region of hair bundles.Can dephosphorylate a broad range of phosphatidylinositolphosphates, including phosphatidylinositol 3,4,5-trisphosphate andmost phosphatidylinositol monophosphates and diphosphates.Phosphate can be hydrolyzed from the D3 and D5 positions in theinositol ring. Has low tyrosine-protein phosphatase activity;however, the relevance of such activity in vivo is unclear. Playsan important role in adipogenesis of mesenchymal stem cells(MSCs). Regulates the phosphorylation state of AKT1 by suppressingthe phosphatidylinositol 3,4,5-trisphosphate (PIP3) level in MSCsand preadipocyte cells. {ECO:0000269|PubMed:19351528}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 2036_2292 | 1891 | 2296 | Domain | Tyrosine-protein phosphatase |
| Tgene | >PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1969_2332 | 1891 | 2296 | Topological domain | Cytoplasmic |
| Tgene | >PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1948_1968 | 1891 | 2296 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 100_195 | 1891 | 2296 | Domain | Fibronectin type-III 2 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1098_1190 | 1891 | 2296 | Domain | Fibronectin type-III 12 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1192_1282 | 1891 | 2296 | Domain | Fibronectin type-III 13 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1287_1380 | 1891 | 2296 | Domain | Fibronectin type-III 14 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1384_1470 | 1891 | 2296 | Domain | Fibronectin type-III 15 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1474_1578 | 1891 | 2296 | Domain | Fibronectin type-III 16 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1583_1681 | 1891 | 2296 | Domain | Fibronectin type-III 17 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 1686_1787 | 1891 | 2296 | Domain | Fibronectin type-III 18 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 199_294 | 1891 | 2296 | Domain | Fibronectin type-III 3 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 350_438 | 1891 | 2296 | Domain | Fibronectin type-III 4 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 36_99 | 1891 | 2296 | Domain | Fibronectin type-III 1 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 441_539 | 1891 | 2296 | Domain | Fibronectin type-III 5 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 514_606 | 1891 | 2296 | Domain | Fibronectin type-III 6 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 610_705 | 1891 | 2296 | Domain | Fibronectin type-III 7 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 710_799 | 1891 | 2296 | Domain | Fibronectin type-III 8 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 804_894 | 1891 | 2296 | Domain | Fibronectin type-III 9 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 899_988 | 1891 | 2296 | Domain | Fibronectin type-III 10 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 993_1093 | 1891 | 2296 | Domain | Fibronectin type-III 11 |
| Tgene | PTPRQ | chr12:82796909 | chr12:81025971 | ENST00000266688 | + | 37 | 50 | 36_1947 | 1891 | 2296 | Topological domain | Extracellular |
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FusionGeneSequence for METTL25_PTPRQ |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_METTL25_ENST00000248306_chr12_82796909_+_PTPRQ_ENST00000266688_chr12_81025971_+_831aa MAASCPLPVTPDLPTLRAKLQGLLQFLRDALSISNAHTVDFYTESVWEELVDLPPETVLAALRKSASETEALPSETRPLVEAEWEAGMTD FPKIFCETSQKLVSVEAFALAAKYYSVQNLGICTPFEQLLVALRGNQNQRIGENQKAVEFMNMKKSHEVQAMSELISSIADYYGIKQVID LGSGKGYLSSFLSLKYGLKVYGIDSSNTNTHGAEERNRKLKKHWKLCHAQSRLDVNGLALKMAKERKVQNKVKNKADTEEVFNNSPTNQE KMPTSAILPDFSGSVISNIRNQMETLHSQPHQEENLCFENSFSLINLLPINAVEPTSSQQIPNRETSEANKERRKMTSKSSESNIYSPLT SFITADSELHDIIKDLEDCLMVGLHTCGDLAPNTLRIFTSNSEIKGVCSVGCCYHLLSEEFENQHKGEGLSERTVEIILSVTLCILSIIL LGTAIFAFARIRQKQKEGGTYSPQDAEIIDTKLKLDQLITVADLELKDERLTRLLSYRKSIKPISKKSFLQHVEELCTNNNLKFQEEFSE LPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIADASVPGSDYINASYISGYLCPNEFIATQGPLPGTVGDFWRMVWETRAKTLV MLTQCFEKGRIRCHQYWPEDNKPVTVFGDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFTAWPEHGVPENSAPLIHFVKLVRASR AHDTTPMIVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLSNKGSNQPICFVNYSALQK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_METTL25_ENST00000248306_chr12_82796909_+_PTPRQ_ENST00000266688_chr12_81025971_+_2493nt ATGGCGGCTTCTTGCCCTCTCCCGGTGACCCCGGACCTGCCCACGCTGCGTGCCAAGTTGCAGGGACTGCTGCAGTTCCTGAGGGATGCC CTGTCCATTTCCAATGCACATACCGTGGATTTCTACACAGAATCCGTGTGGGAGGAGCTGGTCGACTTGCCACCGGAGACAGTGCTGGCT GCGCTGAGGAAGTCAGCGTCGGAGACGGAGGCCCTGCCCTCAGAGACGCGCCCCCTAGTGGAAGCAGAGTGGGAAGCAGGTATGACTGAT TTTCCCAAAATATTTTGTGAAACTTCTCAGAAGTTGGTGAGTGTGGAAGCCTTTGCTCTGGCTGCGAAATACTATTCTGTACAAAACTTG GGAATATGTACTCCTTTTGAACAGTTGCTTGTAGCCCTTCGAGGAAATCAAAACCAGAGAATTGGTGAAAATCAGAAGGCAGTTGAGTTT ATGAATATGAAGAAATCTCATGAAGTTCAGGCAATGTCAGAGCTGATCAGCAGTATTGCTGACTACTATGGAATAAAGCAGGTGATTGAC TTGGGTTCCGGTAAAGGCTACCTAAGCTCTTTTTTGTCCTTGAAGTATGGCTTAAAAGTTTATGGAATTGATTCTTCAAATACCAATACT CATGGAGCTGAGGAGAGAAACAGAAAATTGAAGAAACATTGGAAACTCTGTCATGCTCAGTCAAGATTAGATGTCAATGGACTAGCATTA AAAATGGCAAAAGAAAGGAAAGTGCAAAATAAAGTTAAAAATAAAGCTGATACTGAGGAAGTGTTTAACAACAGTCCTACAAATCAAGAA AAGATGCCTACCTCAGCTATTTTGCCTGATTTTTCTGGCTCTGTAATTTCTAATATCAGAAACCAAATGGAAACCCTTCATTCTCAGCCA CATCAAGAAGAAAATTTGTGTTTTGAAAATTCCTTTTCTCTTATAAACCTTTTGCCTATTAATGCTGTAGAGCCTACTTCTTCACAGCAA ATACCCAACAGAGAAACATCTGAAGCCAATAAAGAGAGAAGAAAAATGACATCAAAGTCAAGTGAATCAAATATATATTCACCTTTAACC TCTTTTATCACTGCTGATTCAGAACTCCATGACATTATTAAAGATTTGGAGGATTGTTTGATGGTGGGTCTCCACACTTGTGGTGATCTG GCTCCAAATACTTTGCGAATATTTACCTCCAACTCTGAAATCAAGGGAGTTTGCAGTGTGGGTTGTTGCTACCACCTCTTATCTGAAGAA TTTGAAAACCAGCATAAAGGGGAAGGACTTTCAGAAAGAACCGTAGAGATCATTCTTTCCGTCACTTTGTGTATCCTTTCAATAATTCTC CTTGGAACAGCTATTTTTGCATTTGCAAGAATTCGACAGAAGCAGAAAGAAGGTGGCACATACTCTCCTCAGGATGCAGAAATTATTGAC ACTAAATTGAAGCTGGATCAGCTCATCACAGTGGCAGACCTGGAACTGAAGGACGAGAGATTAACGCGGTTACTTAGTTATAGAAAATCC ATCAAGCCAATAAGCAAGAAATCCTTCCTGCAACATGTTGAAGAGCTTTGCACAAACAACAACCTAAAGTTTCAAGAAGAATTTTCGGAA TTACCAAAATTTCTTCAGGATCTTTCTTCAACTGATGCTGATCTGCCTTGGAATAGAGCAAAAAACCGCTTCCCAAACATAAAACCATAT AATAATAACAGAGTAAAGCTGATAGCTGACGCTAGTGTTCCAGGTTCGGATTATATTAATGCCAGCTATATTTCTGGTTATTTATGTCCA AATGAATTTATTGCTACTCAAGGTCCACTACCAGGAACAGTTGGAGATTTTTGGAGAATGGTGTGGGAAACCAGAGCAAAAACATTAGTA ATGCTAACACAGTGTTTTGAAAAAGGACGGATCAGATGCCATCAGTATTGGCCAGAGGACAACAAGCCAGTTACTGTCTTTGGAGATATA GTGATTACAAAGCTAATGGAGGATGTTCAAATAGATTGGACTATCAGGGATCTGAAAATTGAAAGGCATGGGGATTGCATGACTGTTCGA CAGTGTAACTTTACTGCCTGGCCAGAGCATGGGGTTCCTGAGAACAGCGCCCCTCTAATTCACTTTGTGAAGTTGGTTCGAGCAAGCAGG GCACATGACACCACACCTATGATTGTTCACTGCAGTGCTGGAGTTGGAAGAACTGGAGTTTTTATTGCTCTGGACCATTTAACACAACAT ATAAATGACCATGATTTTGTGGATATATATGGACTAGTAGCTGAACTGAGAAGTGAAAGAATGTGCATGGTGCAGAATCTGGCACAGTAT ATCTTTTTACACCAGTGCATTCTGGATCTCTTATCAAATAAGGGAAGTAATCAGCCCATCTGTTTTGTTAACTATTCAGCACTTCAGAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_METTL25_ENST00000248306_chr12_82796909_+_PTPRQ_ENST00000266688_chr12_81025971_+_2562nt GCTAATTTGGGCCGAGCTGGCGCCTCACGGCCATGTTTGCGCCACCTACAGCCTCGGAGGGTGAGCGTCATGGCGGCTTCTTGCCCTCTC CCGGTGACCCCGGACCTGCCCACGCTGCGTGCCAAGTTGCAGGGACTGCTGCAGTTCCTGAGGGATGCCCTGTCCATTTCCAATGCACAT ACCGTGGATTTCTACACAGAATCCGTGTGGGAGGAGCTGGTCGACTTGCCACCGGAGACAGTGCTGGCTGCGCTGAGGAAGTCAGCGTCG GAGACGGAGGCCCTGCCCTCAGAGACGCGCCCCCTAGTGGAAGCAGAGTGGGAAGCAGGTATGACTGATTTTCCCAAAATATTTTGTGAA ACTTCTCAGAAGTTGGTGAGTGTGGAAGCCTTTGCTCTGGCTGCGAAATACTATTCTGTACAAAACTTGGGAATATGTACTCCTTTTGAA CAGTTGCTTGTAGCCCTTCGAGGAAATCAAAACCAGAGAATTGGTGAAAATCAGAAGGCAGTTGAGTTTATGAATATGAAGAAATCTCAT GAAGTTCAGGCAATGTCAGAGCTGATCAGCAGTATTGCTGACTACTATGGAATAAAGCAGGTGATTGACTTGGGTTCCGGTAAAGGCTAC CTAAGCTCTTTTTTGTCCTTGAAGTATGGCTTAAAAGTTTATGGAATTGATTCTTCAAATACCAATACTCATGGAGCTGAGGAGAGAAAC AGAAAATTGAAGAAACATTGGAAACTCTGTCATGCTCAGTCAAGATTAGATGTCAATGGACTAGCATTAAAAATGGCAAAAGAAAGGAAA GTGCAAAATAAAGTTAAAAATAAAGCTGATACTGAGGAAGTGTTTAACAACAGTCCTACAAATCAAGAAAAGATGCCTACCTCAGCTATT TTGCCTGATTTTTCTGGCTCTGTAATTTCTAATATCAGAAACCAAATGGAAACCCTTCATTCTCAGCCACATCAAGAAGAAAATTTGTGT TTTGAAAATTCCTTTTCTCTTATAAACCTTTTGCCTATTAATGCTGTAGAGCCTACTTCTTCACAGCAAATACCCAACAGAGAAACATCT GAAGCCAATAAAGAGAGAAGAAAAATGACATCAAAGTCAAGTGAATCAAATATATATTCACCTTTAACCTCTTTTATCACTGCTGATTCA GAACTCCATGACATTATTAAAGATTTGGAGGATTGTTTGATGGTGGGTCTCCACACTTGTGGTGATCTGGCTCCAAATACTTTGCGAATA TTTACCTCCAACTCTGAAATCAAGGGAGTTTGCAGTGTGGGTTGTTGCTACCACCTCTTATCTGAAGAATTTGAAAACCAGCATAAAGGG GAAGGACTTTCAGAAAGAACCGTAGAGATCATTCTTTCCGTCACTTTGTGTATCCTTTCAATAATTCTCCTTGGAACAGCTATTTTTGCA TTTGCAAGAATTCGACAGAAGCAGAAAGAAGGTGGCACATACTCTCCTCAGGATGCAGAAATTATTGACACTAAATTGAAGCTGGATCAG CTCATCACAGTGGCAGACCTGGAACTGAAGGACGAGAGATTAACGCGGTTACTTAGTTATAGAAAATCCATCAAGCCAATAAGCAAGAAA TCCTTCCTGCAACATGTTGAAGAGCTTTGCACAAACAACAACCTAAAGTTTCAAGAAGAATTTTCGGAATTACCAAAATTTCTTCAGGAT CTTTCTTCAACTGATGCTGATCTGCCTTGGAATAGAGCAAAAAACCGCTTCCCAAACATAAAACCATATAATAATAACAGAGTAAAGCTG ATAGCTGACGCTAGTGTTCCAGGTTCGGATTATATTAATGCCAGCTATATTTCTGGTTATTTATGTCCAAATGAATTTATTGCTACTCAA GGTCCACTACCAGGAACAGTTGGAGATTTTTGGAGAATGGTGTGGGAAACCAGAGCAAAAACATTAGTAATGCTAACACAGTGTTTTGAA AAAGGACGGATCAGATGCCATCAGTATTGGCCAGAGGACAACAAGCCAGTTACTGTCTTTGGAGATATAGTGATTACAAAGCTAATGGAG GATGTTCAAATAGATTGGACTATCAGGGATCTGAAAATTGAAAGGCATGGGGATTGCATGACTGTTCGACAGTGTAACTTTACTGCCTGG CCAGAGCATGGGGTTCCTGAGAACAGCGCCCCTCTAATTCACTTTGTGAAGTTGGTTCGAGCAAGCAGGGCACATGACACCACACCTATG ATTGTTCACTGCAGTGCTGGAGTTGGAAGAACTGGAGTTTTTATTGCTCTGGACCATTTAACACAACATATAAATGACCATGATTTTGTG GATATATATGGACTAGTAGCTGAACTGAGAAGTGAAAGAATGTGCATGGTGCAGAATCTGGCACAGTATATCTTTTTACACCAGTGCATT CTGGATCTCTTATCAAATAAGGGAAGTAATCAGCCCATCTGTTTTGTTAACTATTCAGCACTTCAGAAGATGGACTCTTTGGACGCCATG |
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FusionGenePPI for METTL25_PTPRQ |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| METTL25 | APP, HTR3C, NRD1, PCBP3, RPGRIP1 | PTPRQ | EEA1, PIBF1, SNX27, SLC9A3R1, AHI1, ATP2B2, SLC9A3R2, EZR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for METTL25_PTPRQ |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for METTL25_PTPRQ |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PTPRQ | C3150654 | DEAFNESS, AUTOSOMAL RECESSIVE 84A | 1 | CTD_human;UNIPROT |
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