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Fusion gene ID: 21566 |
FusionGeneSummary for MED26_PLCB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MED26_PLCB1 | Fusion gene ID: 21566 | Hgene | Tgene | Gene symbol | MED26 | PLCB1 | Gene ID | 9441 | 23236 |
| Gene name | mediator complex subunit 26 | phospholipase C beta 1 | |
| Synonyms | CRSP7|CRSP70 | EIEE12|PI-PLC|PLC-154|PLC-I|PLC-beta-1|PLC154|PLCB1A|PLCB1B | |
| Cytomap | 19p13.11 | 20p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mediator of RNA polymerase II transcription subunit 26ARC70CRSP complex subunit 7activator-recruited cofactor 70 kDa componentcofactor required for Sp1 transcriptional activation subunit 7cofactor required for Sp1 transcriptional activation, subunit | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-11-phosphatidyl-D-myo-inositol-4,5-bisphosphateinositoltrisphosphohydrolasemonophosphatidylinositol phosphodiesterasephosphoinositidase Cphospholipase C, beta 1 (phosphoinositide-specific | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | O95402 | Q9NQ66 | |
| Ensembl transtripts involved in fusion gene | ENST00000263390, | ENST00000378641, ENST00000338037, ENST00000378637, ENST00000494924, | |
| Fusion gene scores | * DoF score | 15 X 6 X 10=900 | 6 X 5 X 4=120 |
| # samples | 15 | 5 | |
| ** MAII score | log2(15/900*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/120*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MED26 [Title/Abstract] AND PLCB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MED26 | GO:0006357 | regulation of transcription by RNA polymerase II | 15989967 |
| Tgene | PLCB1 | GO:0035722 | interleukin-12-mediated signaling pathway | 11743656 |
| Tgene | PLCB1 | GO:0035723 | interleukin-15-mediated signaling pathway | 11743656 |
| Tgene | PLCB1 | GO:0046330 | positive regulation of JNK cascade | 9500449 |
| Tgene | PLCB1 | GO:0070498 | interleukin-1-mediated signaling pathway | 8872139 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-QQ-A5VB-01A | MED26 | chr19 | 16738683 | - | PLCB1 | chr20 | 8608941 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000263390 | ENST00000378641 | MED26 | chr19 | 16738683 | - | PLCB1 | chr20 | 8608941 | + |
| In-frame | ENST00000263390 | ENST00000338037 | MED26 | chr19 | 16738683 | - | PLCB1 | chr20 | 8608941 | + |
| In-frame | ENST00000263390 | ENST00000378637 | MED26 | chr19 | 16738683 | - | PLCB1 | chr20 | 8608941 | + |
| 5CDS-intron | ENST00000263390 | ENST00000494924 | MED26 | chr19 | 16738683 | - | PLCB1 | chr20 | 8608941 | + |
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FusionProtFeatures for MED26_PLCB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MED26 | PLCB1 |
| Component of the Mediator complex, a coactivatorinvolved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge toconvey information from gene-specific regulatory proteins to thebasal RNA polymerase II transcription machinery. Mediator isrecruited to promoters by direct interactions with regulatoryproteins and serves as a scaffold for the assembly of a functionalpre-initiation complex with RNA polymerase II and the generaltranscription factors. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000338037 | + | 2 | 32 | 316_467 | 82 | 1217 | Domain | PI-PLC X-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000338037 | + | 2 | 32 | 540_656 | 82 | 1217 | Domain | PI-PLC Y-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000338037 | + | 2 | 32 | 663_761 | 82 | 1217 | Domain | C2 |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378637 | + | 2 | 32 | 316_467 | 82 | 1174 | Domain | PI-PLC X-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378637 | + | 2 | 32 | 540_656 | 82 | 1174 | Domain | PI-PLC Y-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378637 | + | 2 | 32 | 663_761 | 82 | 1174 | Domain | C2 |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378641 | + | 2 | 33 | 316_467 | 82 | 2075 | Domain | PI-PLC X-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378641 | + | 2 | 33 | 540_656 | 82 | 2075 | Domain | PI-PLC Y-box |
| Tgene | >PLCB1 | chr19:16738683 | chr20:8608941 | ENST00000378641 | + | 2 | 33 | 663_761 | 82 | 2075 | Domain | C2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MED26 | chr19:16738683 | chr20:8608941 | ENST00000263390 | - | 1 | 3 | 228_325 | 24 | 601 | Compositional bias | Note=Pro-rich |
| Hgene | >MED26 | chr19:16738683 | chr20:8608941 | ENST00000263390 | - | 1 | 3 | 10_87 | 24 | 601 | Domain | TFIIS N-terminal |
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FusionGeneSequence for MED26_PLCB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378641_chr20_8608941_+_1116aa MTAAPASPQQIRDRLLQAIDPQSNDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR DAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFIN SSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEAD TESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIY PKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFL SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRN ERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTT TLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQND YLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDE >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000338037_chr20_8608941_+_1159aa MTAAPASPQQIRDRLLQAIDPQSNDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR DAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFIN SSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEAD TESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIY PKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFL SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRN ERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTT TLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQND YLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDE >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378637_chr20_8608941_+_1116aa MTAAPASPQQIRDRLLQAIDPQSNDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSR DAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKP YLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFIN SSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSP KQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEAD TESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIY PKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFL SDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRN ERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTT TLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQND YLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEE CQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378641_chr20_8608941_+_3348nt ATGACAGCGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAA CTTTTGGATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAAT CTCGTGGCTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGG GATGCATTTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTT TCAGCAGATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACT CCAGAAGTGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCA TATCTTACCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAA GAGCAAGTCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTAT CTGAGTGGAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAAT TCCTCGCACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGC TGTGTGGAGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTC AAGGAAGTGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCA AAGCAGCAAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCT GGAGTTCCTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGC AAAAAGAAGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGAT ACGGAAAGTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAA GAAATGTCTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCT TCCTTCGTGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATAT CCAAAAGGAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACA ATGGACCTGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCT GACAAGCATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTT TCTGATAAGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCC CAAGGAAATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCA GTTTATGAAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAAT GAAAGGAACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAA GCTTTATCAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTA AAGAAAGAGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACA ACCCTGACACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATT CAGAGTGTCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAA GAAATGAAAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGAC TACTTGAGAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCA ACGATTGAGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAAT CTTCGGCAAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAG TGTCAGAACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAG AAGATAACAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAG TATATCAAGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAA AAGCCCAAGGGGGAAGGTTCCTCCTCATTCTTGTCGGAAACTTGCCATGAGGATCCCTCTGTTTCCCCCAACTTTACTCCCCCCAACCCT >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000338037_chr20_8608941_+_3477nt ATGACAGCGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAA CTTTTGGATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAAT CTCGTGGCTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGG GATGCATTTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTT TCAGCAGATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACT CCAGAAGTGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCA TATCTTACCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAA GAGCAAGTCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTAT CTGAGTGGAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAAT TCCTCGCACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGC TGTGTGGAGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTC AAGGAAGTGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCA AAGCAGCAAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCT GGAGTTCCTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGC AAAAAGAAGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGAT ACGGAAAGTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAA GAAATGTCTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCT TCCTTCGTGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATAT CCAAAAGGAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACA ATGGACCTGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCT GACAAGCATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTT TCTGATAAGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCC CAAGGAAATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCA GTTTATGAAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAAT GAAAGGAACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAA GCTTTATCAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTA AAGAAAGAGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACA ACCCTGACACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATT CAGAGTGTCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAA GAAATGAAAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGAC TACTTGAGAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCA ACGATTGAGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAAT CTTCGGCAAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAG TGTCAGAACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAG AAGATAACAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAG TATATCAAGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAA AAGCCCAAGCTGCAGGTGGAGCTGGAGCAAGAATACCAAGACAAATTCAAAAGACTGCCCCTCGAGATTTTGGAATTCGTGCAGGAAGCC ATGAAAGGAAAGATCAGTGAAGACAGCAATCACGGTTCTGCCCCTCTCTCCCTGTCCTCAGACCCTGGAAAAGTGAACCACAAGACTCCC >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378637_chr20_8608941_+_3348nt ATGACAGCGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAA CTTTTGGATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAAT CTCGTGGCTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGG GATGCATTTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTT TCAGCAGATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACT CCAGAAGTGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCA TATCTTACCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAA GAGCAAGTCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTAT CTGAGTGGAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAAT TCCTCGCACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGC TGTGTGGAGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTC AAGGAAGTGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCA AAGCAGCAAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCT GGAGTTCCTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGC AAAAAGAAGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGAT ACGGAAAGTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAA GAAATGTCTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCT TCCTTCGTGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATAT CCAAAAGGAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACA ATGGACCTGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCT GACAAGCATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTT TCTGATAAGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCC CAAGGAAATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCA GTTTATGAAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAAT GAAAGGAACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAA GCTTTATCAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTA AAGAAAGAGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACA ACCCTGACACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATT CAGAGTGTCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAA GAAATGAAAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGAC TACTTGAGAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCA ACGATTGAGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAAT CTTCGGCAAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAG TGTCAGAACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAG AAGATAACAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAG TATATCAAGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAA AAGCCCAAGGGGGAAGGTTCCTCCTCATTCTTGTCGGAAACTTGCCATGAGGATCCCTCTGTTTCCCCCAACTTTACTCCCCCCAACCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378641_chr20_8608941_+_6909nt TCACTGGAGTTTGGTTCTCGAGGCGGCGGCAGCGAGCGGCGGCGGCTCCGGCGGCTCCTCCTCCTCCTTTGGTGGCGGCGGCGGCCCGGG ACCGAGACCCGGCCCCGGCTCCCCTCTCCGCCACCCCGCGCGCCCCCAACCCCCCGGCGCCGCGGGGAACATGCGGCTCCGGCTCCCGGA GGCCGGCGAGTGAGTGACCCCCGTCCCCCGCCTCAGCCCGCCCGCCCGCTGGCCCGGCCGCAACCCCCCGCCTCGCCCAGGCAATGACAG CGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAACTTTTGG ATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAATCTCGTGG CTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGGGATGCAT TTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTTTCAGCAG ATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACTCCAGAAG TGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCATATCTTA CCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAAGAGCAAG TCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTATCTGAGTG GAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAATTCCTCGC ACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGCTGTGTGG AGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTCAAGGAAG TGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCAAAGCAGC AAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCTGGAGTTC CTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGCAAAAAGA AGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGATACGGAAA GTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAAGAAATGT CTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCTTCCTTCG TGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATATCCAAAAG GAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACAATGGACC TGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCTGACAAGC ATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTTTCTGATA AGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCCCAAGGAA ATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCAGTTTATG AAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAATGAAAGGA ACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAAGCTTTAT CAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTAAAGAAAG AGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACAACCCTGA CACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATTCAGAGTG TCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAAGAAATGA AAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGACTACTTGA GAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCAACGATTG AGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAATCTTCGGC AAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAGTGTCAGA ACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAGAAGATAA CAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAGTATATCA AGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAAAAGCCCA AGGGGGAAGGTTCCTCCTCATTCTTGTCGGAAACTTGCCATGAGGATCCCTCTGTTTCCCCCAACTTTACTCCCCCCAACCCTCAAGCTC TCAAGTGGTGACCACCGTCCTTCCGGCCAGCTGCAGGTGGAGCTGGAGCAAGAATACCAAGACAAATTCAAAAGACTGCCCCTCGAGATT TTGGAATTCGTGCAGGAAGCCATGAAAGGAAAGATCAGTGAAGACAGCAATCACGGTTCTGCCCCTCTCTCCCTGTCCTCAGACCCTGGA AAAGTGAACCACAAGACTCCCTCCAGTGAGGAGCTGGGAGGAGACATCCCAGGAAAAGAATTTGATACTCCTCTGTGAATGCTCCTGCCA GGCCTTCAGAAATTGCATGGCCACTCCAGCGTCATCGGACTCTCTCTTATTACAAAGATCACTGCCCAGGACCATCTTCCCGAGAAGCAT CCCTTAGCCTAAAATCCACACCAAAGGGAGAGTTCCAGAGGAATCCATGAAGAATTCCCATGCCCAGGCTCCATGTGTCATGTGGAAACC TCCACAGGTCTGCTAGTGAAGAATGCATGTATGTGAGATTTTTGTTTTCTTTCCAATAGCAAATTCAAAGCAAGCAACTTGCAGGCTCCA TGGAACTTTTAATGAAGGACAGTGTCTTCTTTGAAGAAAATCAAGCTCGTGTTTTTATTCGAAGCTCTGGTGTAAAATATTTCAAAGTCA TAGAAATAGTTTGAGAAATGCATAGCATTATTTAACACTATTGAACAGCCGACTTTGAGCATTGTTTCTTCTAACTGCCCCTCAACTACC ATTATCTTCAAGTCAACATGCATATTACATTTTCATCCTTTGCTTTGCAAGCACTGGTGGCTTGCAGTTTGCTAATTTATTTATCATAGA GTCATCAATGTATTTGTTGCTGACATGGTTTTATTAGATACTGTAGTGATTCAAATAAGTTTTCTATTTGAAAAAAAAAATCACTTGATT GTATCCTTGCCCAGTGAAGCCATCCTAAGACTTAGCAATATGGATTGTACATTTGGCTGCATGAGCAAGTCGGCCGCACACTTCCAGACA GTGTGCTGTTTGAATTGACTATTTGCACTCAAAGTCTGGGTATTCATTGGTTATTGGCCTGAAATGATCAAATAACTACAAATGATCTGT TGAATAAAAATAGTTGAGCTGATATATGTTAAGCAGATATTCAATCAGAATGAACAGGTTCCGGTGGTTATTTTGCCGTTTGACATTTTT TATGGTTCATTTATTTTTAATATAGAGAGGAAGATTGAATATTTATCTAGAGAATACAAAGACCCACATGTAAATGATAGGTATTATCTC CATGTATATATGTACCCACTTAGTCATGTAAGTGCATATACACATACACACACATGAGTGTAGACATGTGTTTATTAATTGACAATGACC CAAATCTCTTCCACAAGACTTAAAACCAAATTCAGGGACAAATGGATAGAGAAGAAAAGGGTCAAACATCGAGATTACATGGATGTTAAA TTATATGGAGACGCTAAGAAATAATTGATGGAGCCATTGATGCAAACCGAAGTAGATTTAGAACTTATATGAATTTGATTTATATTTTGC AAGATCAAAAATTAGATGTTAAGTATCAGATTTTAAGCTTGTTTTAATGGTCAAAAAATTAGGACAGAAATAATATGGACATTTATTAGT ATCTTCCATAATTTTTAAGTCTGACACATTTCTATTTTATTCTAACATAAAAAAACTTCCATTATATATTTACTAAGTATATTTAATTCA CTTAACTCTGTCTTTATAAGTTCCTATTTTAGATGGAATAAGAGAAACAAATTATATCAAGGTAAAACTGATCAAAAGCATAATTGAAAG TTCTGAAAAAAGAAAAATAATAATATGTAGAAAAATGTAACTTAGAGAGTAACACATGAACATTGAAGTTAAAACCCAGAAGCCAGATGC TCACAGTTTTATTTTACTTTAAAATAAACCTGTCTGACTGTAGCTTTGTGAAATATCTTAAAACGCAAAAACCAATTGTGTCCTGAAAAT TGTTTCAAGAATTTAATATTTTTATGAAAATTATTTTATTTAACTTTAAGCAATAACTAGAGATTACAATTAAATTTTAATCAAAATGAA GGCTTAGTTCAAACATAAGGAAACAGTGTTTGATTAAAAAAAACACATCTAGTAAGACGTAAGGGGAAAATCACATCCTCTTTGGAGATG ATTATATTTTGATCTGAAGGGTTTGGGGTGTTCATTAGACACTTAATAAAACTTAACTTCCAATGAAAAAGAAATCTTTTGTAAATCATT CTACTTTTGCACTTTGAAAGAAAGGCGTTAATCATAAAGAAGCAAGAATGGTCAAAATCGAATGCTGCATTTTTATAAACAAAATTACAG ACTGTCTGAAATTGAAGAAGAATGAACTAATAATAGCATTCATAACCAAACACAATGATGATTATTGCAGAACATTGTATCACATTTTAG TCCAGAGATAGAATAAAGTTGAATAACCTTGACTTACACAAAACTGTTTTGGTAGTTGGATTTCATTATCTTAGTGAATTTAGTCATTTT ACAATATGTTTGTATTTGGCCATTTACTGTAATCACATTTTTATATCTGTACAATGACACTTTTTGCAGTTGTGGGGTAGTGTGTAACAC TGTCCATCTTGCATCATTGAAACTACTACAATGATACTATCATTTAATAATATTAATATTACTTGAAATAGACTAAGATAAAGAAAAGGG GTCTGTATGATGTGCAGTTTTGTGCCTTTATGTATTTGCCTTGTTCTTTGTCGAATGTGTGAAATTCCGTACTGTGGTTTTTCCTATAAT AGAAAGTAGAGCTGTGTATTAAATTAGACTGTGTCTCTCTGATACCTTTACACTACTGAGAATAGCATGGTTTTGGCCATGTAAACCAAT TTTCAAAGTTCTAATGACATAGCCATGTGTTTTTGGTTTTTTATATTTCATTTTAAAATTTGAGTATCACCATACATTAATTAATACTCC TGTAGTAGATAAGCTGTCATTAAGTAATTCCCAAAAAAAGGGCCATTTGCTTGCATTACTTTGAATTTAATGTTGCGCTTGTGCACTGTG TTAATATTGTTTGTGATGGATTGGACGTTGTGACTCTTGCCTTTTAAGAAGAAAAAAAAGATAGGACAAAGTATTTGAAGCTCTTAAAAT GTACATATTTTGGTTCTTCTATCTCAAATTATTTAAAATGCATAATTCACATTTTTGTAATAATTCTATGCAATTTTGTGGCATGATGTT >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000338037_chr20_8608941_+_6791nt TCACTGGAGTTTGGTTCTCGAGGCGGCGGCAGCGAGCGGCGGCGGCTCCGGCGGCTCCTCCTCCTCCTTTGGTGGCGGCGGCGGCCCGGG ACCGAGACCCGGCCCCGGCTCCCCTCTCCGCCACCCCGCGCGCCCCCAACCCCCCGGCGCCGCGGGGAACATGCGGCTCCGGCTCCCGGA GGCCGGCGAGTGAGTGACCCCCGTCCCCCGCCTCAGCCCGCCCGCCCGCTGGCCCGGCCGCAACCCCCCGCCTCGCCCAGGCAATGACAG CGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAACTTTTGG ATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAATCTCGTGG CTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGGGATGCAT TTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTTTCAGCAG ATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACTCCAGAAG TGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCATATCTTA CCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAAGAGCAAG TCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTATCTGAGTG GAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAATTCCTCGC ACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGCTGTGTGG AGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTCAAGGAAG TGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCAAAGCAGC AAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCTGGAGTTC CTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGCAAAAAGA AGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGATACGGAAA GTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAAGAAATGT CTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCTTCCTTCG TGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATATCCAAAAG GAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACAATGGACC TGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCTGACAAGC ATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTTTCTGATA AGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCCCAAGGAA ATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCAGTTTATG AAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAATGAAAGGA ACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAAGCTTTAT CAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTAAAGAAAG AGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACAACCCTGA CACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATTCAGAGTG TCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAAGAAATGA AAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGACTACTTGA GAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCAACGATTG AGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAATCTTCGGC AAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAGTGTCAGA ACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAGAAGATAA CAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAGTATATCA AGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAAAAGCCCA AGCTGCAGGTGGAGCTGGAGCAAGAATACCAAGACAAATTCAAAAGACTGCCCCTCGAGATTTTGGAATTCGTGCAGGAAGCCATGAAAG GAAAGATCAGTGAAGACAGCAATCACGGTTCTGCCCCTCTCTCCCTGTCCTCAGACCCTGGAAAAGTGAACCACAAGACTCCCTCCAGTG AGGAGCTGGGAGGAGACATCCCAGGAAAAGAATTTGATACTCCTCTGTGAATGCTCCTGCCAGGCCTTCAGAAATTGCATGGCCACTCCA GCGTCATCGGACTCTCTCTTATTACAAAGATCACTGCCCAGGACCATCTTCCCGAGAAGCATCCCTTAGCCTAAAATCCACACCAAAGGG AGAGTTCCAGAGGAATCCATGAAGAATTCCCATGCCCAGGCTCCATGTGTCATGTGGAAACCTCCACAGGTCTGCTAGTGAAGAATGCAT GTATGTGAGATTTTTGTTTTCTTTCCAATAGCAAATTCAAAGCAAGCAACTTGCAGGCTCCATGGAACTTTTAATGAAGGACAGTGTCTT CTTTGAAGAAAATCAAGCTCGTGTTTTTATTCGAAGCTCTGGTGTAAAATATTTCAAAGTCATAGAAATAGTTTGAGAAATGCATAGCAT TATTTAACACTATTGAACAGCCGACTTTGAGCATTGTTTCTTCTAACTGCCCCTCAACTACCATTATCTTCAAGTCAACATGCATATTAC ATTTTCATCCTTTGCTTTGCAAGCACTGGTGGCTTGCAGTTTGCTAATTTATTTATCATAGAGTCATCAATGTATTTGTTGCTGACATGG TTTTATTAGATACTGTAGTGATTCAAATAAGTTTTCTATTTGAAAAAAAAAATCACTTGATTGTATCCTTGCCCAGTGAAGCCATCCTAA GACTTAGCAATATGGATTGTACATTTGGCTGCATGAGCAAGTCGGCCGCACACTTCCAGACAGTGTGCTGTTTGAATTGACTATTTGCAC TCAAAGTCTGGGTATTCATTGGTTATTGGCCTGAAATGATCAAATAACTACAAATGATCTGTTGAATAAAAATAGTTGAGCTGATATATG TTAAGCAGATATTCAATCAGAATGAACAGGTTCCGGTGGTTATTTTGCCGTTTGACATTTTTTATGGTTCATTTATTTTTAATATAGAGA GGAAGATTGAATATTTATCTAGAGAATACAAAGACCCACATGTAAATGATAGGTATTATCTCCATGTATATATGTACCCACTTAGTCATG TAAGTGCATATACACATACACACACATGAGTGTAGACATGTGTTTATTAATTGACAATGACCCAAATCTCTTCCACAAGACTTAAAACCA AATTCAGGGACAAATGGATAGAGAAGAAAAGGGTCAAACATCGAGATTACATGGATGTTAAATTATATGGAGACGCTAAGAAATAATTGA TGGAGCCATTGATGCAAACCGAAGTAGATTTAGAACTTATATGAATTTGATTTATATTTTGCAAGATCAAAAATTAGATGTTAAGTATCA GATTTTAAGCTTGTTTTAATGGTCAAAAAATTAGGACAGAAATAATATGGACATTTATTAGTATCTTCCATAATTTTTAAGTCTGACACA TTTCTATTTTATTCTAACATAAAAAAACTTCCATTATATATTTACTAAGTATATTTAATTCACTTAACTCTGTCTTTATAAGTTCCTATT TTAGATGGAATAAGAGAAACAAATTATATCAAGGTAAAACTGATCAAAAGCATAATTGAAAGTTCTGAAAAAAGAAAAATAATAATATGT AGAAAAATGTAACTTAGAGAGTAACACATGAACATTGAAGTTAAAACCCAGAAGCCAGATGCTCACAGTTTTATTTTACTTTAAAATAAA CCTGTCTGACTGTAGCTTTGTGAAATATCTTAAAACGCAAAAACCAATTGTGTCCTGAAAATTGTTTCAAGAATTTAATATTTTTATGAA AATTATTTTATTTAACTTTAAGCAATAACTAGAGATTACAATTAAATTTTAATCAAAATGAAGGCTTAGTTCAAACATAAGGAAACAGTG TTTGATTAAAAAAAACACATCTAGTAAGACGTAAGGGGAAAATCACATCCTCTTTGGAGATGATTATATTTTGATCTGAAGGGTTTGGGG TGTTCATTAGACACTTAATAAAACTTAACTTCCAATGAAAAAGAAATCTTTTGTAAATCATTCTACTTTTGCACTTTGAAAGAAAGGCGT TAATCATAAAGAAGCAAGAATGGTCAAAATCGAATGCTGCATTTTTATAAACAAAATTACAGACTGTCTGAAATTGAAGAAGAATGAACT AATAATAGCATTCATAACCAAACACAATGATGATTATTGCAGAACATTGTATCACATTTTAGTCCAGAGATAGAATAAAGTTGAATAACC TTGACTTACACAAAACTGTTTTGGTAGTTGGATTTCATTATCTTAGTGAATTTAGTCATTTTACAATATGTTTGTATTTGGCCATTTACT GTAATCACATTTTTATATCTGTACAATGACACTTTTTGCAGTTGTGGGGTAGTGTGTAACACTGTCCATCTTGCATCATTGAAACTACTA CAATGATACTATCATTTAATAATATTAATATTACTTGAAATAGACTAAGATAAAGAAAAGGGGTCTGTATGATGTGCAGTTTTGTGCCTT TATGTATTTGCCTTGTTCTTTGTCGAATGTGTGAAATTCCGTACTGTGGTTTTTCCTATAATAGAAAGTAGAGCTGTGTATTAAATTAGA CTGTGTCTCTCTGATACCTTTACACTACTGAGAATAGCATGGTTTTGGCCATGTAAACCAATTTTCAAAGTTCTAATGACATAGCCATGT GTTTTTGGTTTTTTATATTTCATTTTAAAATTTGAGTATCACCATACATTAATTAATACTCCTGTAGTAGATAAGCTGTCATTAAGTAAT TCCCAAAAAAAGGGCCATTTGCTTGCATTACTTTGAATTTAATGTTGCGCTTGTGCACTGTGTTAATATTGTTTGTGATGGATTGGACGT TGTGACTCTTGCCTTTTAAGAAGAAAAAAAAGATAGGACAAAGTATTTGAAGCTCTTAAAATGTACATATTTTGGTTCTTCTATCTCAAA TTATTTAAAATGCATAATTCACATTTTTGTAATAATTCTATGCAATTTTGTGGCATGATGTTTCTTCCACTTGTAATTTTATGTGCTTTC >In-frame_MED26_ENST00000263390_chr19_16738683_-_PLCB1_ENST00000378637_chr20_8608941_+_3940nt TCACTGGAGTTTGGTTCTCGAGGCGGCGGCAGCGAGCGGCGGCGGCTCCGGCGGCTCCTCCTCCTCCTTTGGTGGCGGCGGCGGCCCGGG ACCGAGACCCGGCCCCGGCTCCCCTCTCCGCCACCCCGCGCGCCCCCAACCCCCCGGCGCCGCGGGGAACATGCGGCTCCGGCTCCCGGA GGCCGGCGAGTGAGTGACCCCCGTCCCCCGCCTCAGCCCGCCCGCCCGCTGGCCCGGCCGCAACCCCCCGCCTCGCCCAGGCAATGACAG CGGCTCCGGCGTCTCCGCAGCAGATCAGGGACCGGCTGCTGCAGGCCATCGACCCCCAGAGCAACGACCCCAAATTACGTGAACTTTTGG ATGTGGGGAACATCGGGCGCCTGGAGCAGCGCATGATCACAGTGGTGTATGGGCCTGACCTCGTGAACATCTCCCATTTGAATCTCGTGG CTTTCCAAGAAGAAGTGGCCAAGGAATGGACAAATGAGGTTTTCAGTTTGGCAACAAACCTGCTGGCCCAAAACATGTCCAGGGATGCAT TTCTGGAAAAAGCCTATACTAAACTTAAGCTGCAAGTCACTCCAGAAGGGCGTATTCCTCTCAAAAACATATATCGCTTGTTTTCAGCAG ATCGGAAGCGAGTTGAAACTGCTTTAGAGGCTTGTAGTCTTCCATCTTCAAGGAATGATTCAATACCTCAAGAAGATTTCACTCCAGAAG TGTACAGAGTTTTCCTCAACAACCTTTGCCCTCGACCTGAAATTGATAACATCTTTTCAGAATTTGGTGCAAAAAGCAAACCATATCTTA CCGTTGATCAGATGATGGATTTTATCAACCTTAAGCAGCGAGATCCTCGGCTTAATGAAATACTTTATCCACCTCTAAAACAAGAGCAAG TCCAAGTATTGATTGAGAAGTATGAACCCAACAACAGCCTCGCCAGAAAAGGACAAATATCAGTGGATGGGTTCATGCGCTATCTGAGTG GAGAAGAAAACGGAGTCGTTTCACCTGAGAAACTGGATTTGAATGAAGACATGTCTCAGCCCCTTTCTCACTATTTCATTAATTCCTCGC ACAACACCTACCTCACAGCTGGCCAACTGGCTGGAAACTCCTCTGTTGAGATGTATCGCCAAGTGCTCCTGTCTGGTTGTCGCTGTGTGG AGCTGGACTGCTGGAAGGGACGGACTGCAGAAGAGGAACCTGTCATCACCCATGGCTTCACCATGACAACTGAAATATCTTTCAAGGAAG TGATAGAAGCAATTGCGGAGTGTGCATTTAAGACTTCACCTTTTCCAATTCTCCTTTCGTTTGAGAACCATGTGGATTCCCCAAAGCAGC AAGCCAAGATGGCGGAGTACTGCCGACTGATCTTTGGGGATGCCCTTCTCATGGAGCCCCTGGAAAAATATCCACTGGAATCTGGAGTTC CTCTTCCAAGCCCTATGGATTTAATGTATAAAATTTTGGTGAAAAATAAGAAGAAATCACACAAGTCATCAGAAGGAAGCGGCAAAAAGA AGCTCTCAGAACAAGCCTCCAACACCTACAGTGACTCCTCCAGCATGTTCGAGCCCTCATCCCCAGGAGCCGGAGAAGCTGATACGGAAA GTGACGACGACGATGATGATGATGACTGTAAAAAATCTTCAATGGATGAGGGGACTGCTGGAAGTGAGGCTATGGCCACAGAAGAAATGT CTAATCTGGTGAACTATATTCAGCCAGTCAAGTTTGAGTCATTTGAAATTTCAAAAAAAAGAAATAAAAGTTTTGAAATGTCTTCCTTCG TGGAAACCAAAGGACTTGAACAACTCACCAAGTCTCCAGTGGAATTTGTAGAATATAACAAAATGCAGCTTAGCAGGATATATCCAAAAG GAACACGTGTGGATTCATCCAACTATATGCCTCAGCTCTTCTGGAATGCAGGTTGTCAGATGGTGGCACTTAATTTCCAGACAATGGACC TGGCTATGCAAATAAATATGGGGATGTATGAATACAACGGGAAGAGTGGCTACAGATTGAAGCCAGAGTTCATGAGGAGGCCTGACAAGC ATTTTGATCCATTTACTGAAGGCATCGTAGATGGGATAGTGGCAAACACTTTGTCTGTTAAGATTATTTCAGGTCAGTTTCTTTCTGATA AGAAAGTTGGGACTTACGTGGAAGTAGATATGTTTGGTTTGCCTGTGGATACAAGGAGGAAGGCATTTAAGACCAAAACATCCCAAGGAA ATGCTGTGAATCCTGTCTGGGAAGAAGAACCTATTGTGTTCAAAAAGGTGGTTCTTCCTACTCTGGCCTGTTTGAGAATAGCAGTTTATG AAGAAGGAGGTAAATTCATTGGCCACCGTATCTTGCCAGTGCAAGCCATTCGGCCAGGCTATCACTATATCTGTCTAAGGAATGAAAGGA ACCAGCCTCTGACGCTGCCTGCTGTCTTTGTCTACATAGAAGTGAAAGACTATGTGCCAGACACATATGCAGATGTCATCGAAGCTTTAT CAAACCCAATCCGATATGTGAACCTGATGGAACAGAGAGCTAAGCAATTGGCTGCTTTGACACTGGAAGATGAAGAAGAAGTAAAGAAAG AGGCTGATCCTGGAGAAACACCATCAGAGGCTCCAAGTGAAGCGAGAACGACTCCAGCAGAAAATGGGGTGAATCACACTACAACCCTGA CACCCAAGCCACCCTCCCAGGCTCTCCACAGCCAGCCAGCTCCAGGTTCTGTAAAGGCACCTGCCAAAACAGAAGATCTTATTCAGAGTG TCTTAACAGAAGTGGAAGCACAGACCATCGAAGAACTAAAGCAACAGAAATCGTTTGTGAAACTTCAAAAGAAACACTACAAAGAAATGA AAGACCTGGTTAAGAGACACCACAAGAAAACCACTGACCTTATCAAAGAACACACTACCAAGTATAATGAAATTCAGAATGACTACTTGA GAAGGAGAGCCGCTTTGGAAAAGTCCGCCAAAAAGGACAGTAAGAAAAAATCGGAACCCAGCAGCCCTGATCATGGTTCATCAACGATTG AGCAAGACCTCGCTGCTCTGGATGCTGAAATGACCCAAAAGTTAATAGACTTGAAGGACAAACAACAGCAGCAGCTGCTTAATCTTCGGC AAGAACAGTATTATAGTGAAAAATACCAGAAGCGAGAACATATTAAACTGCTTATTCAAAAGTTGACGGATGTCGCAGAAGAGTGTCAGA ACAATCAGTTAAAGAAGCTCAAAGAAATCTGTGAGAAAGAAAAGAAAGAATTAAAGAAGAAAATGGATAAAAAGAGGCAGGAGAAGATAA CAGAAGCTAAATCCAAAGACAAAAGTCAGATGGAAGAGGAGAAGACAGAGATGATCCGGTCATATATCCAGGAAGTGGTGCAGTATATCA AGAGGCTAGAAGAAGCGCAAAGTAAACGGCAAGAAAAACTCGTAGAGAAACACAAGGAAATACGTCAGCAGATCCTGGATGAAAAGCCCA AGGGGGAAGGTTCCTCCTCATTCTTGTCGGAAACTTGCCATGAGGATCCCTCTGTTTCCCCCAACTTTACTCCCCCCAACCCTCAAGCTC TCAAGTGGTGACCACCGTCCTTCCGGCCAGGTAGGACTGGATGGGAGGGGTCGCTTTTGAGAGAAGGGTGGTGTGTAGCCATCCAGTTTT CAGGCATCACGGACTTGCTCGTTTGTCCTTCATCCTCCCTTTCTCTACATTCCCATCTTTTTTTTCTGCTAAAGTTCCCAGCCACACCCA TGATCATTTCCTCATCCTTTCTGCCTTCCTCTGGTATTAATTTCTCCATCATTGTGCTCTCTCTTCCTGACATAAATCTCATTCTTCCAT |
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FusionGenePPI for MED26_PLCB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MED26 | MED10, MED9, MED29, MED19, MED28, MED13L, MED13, MED12, MED1, MED14, MED23, MED15, MED24, MED16, MED25, MED17, CDK8, CDK19, MED27, MED4, MED6, MED7, MED8, MED18, MED20, MED30, MED21, MED22, MED11, MED31, POLR2J, POLR2D, POLR2A, POLR2B, POLR2C, POLR2E, POLR2F, POLR2G, POLR2H, POLR2I, POLR2L, CEBPB, TRRAP, SREBF1, ZC3H13, QKI, TADA2A, CTDP1, EPAS1, EAF1, ELL, CDK9, TAF1, TAF4, TAF6, CCNT1, CCNT2, TCEA1, TCEB3, AFF4, MLLT3, TBP, CCNC, POLR2K, TAF2, TAF3, TAF4B, TAF5, TAF7, TAF8, TAF9, TAF10, TAF11, TAF13, TAF15, ELL2, EAF2, AFF1, MLLT1, ICE1, ICE2, EWSR1, MASTL, AURKA, TRIM25 | PLCB1 | TRPM7, SLC9A3R1, SPTBN1, KRIT1, PCF11, GNA11, GNAQ, PLCB1, CTBP1, CTBP2, TFCP2, CEP76, BTN2A1, PTGER3, GAN, DEF8 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MED26_PLCB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MED26_PLCB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PLCB1 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| Tgene | PLCB1 | C0009375 | Colonic Neoplasms | 1 | CTD_human |
| Tgene | PLCB1 | C0030193 | Pain | 1 | CTD_human |
| Tgene | PLCB1 | C0036341 | Schizophrenia | 1 | CTD_human |
| Tgene | PLCB1 | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Tgene | PLCB1 | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| Tgene | PLCB1 | C3463824 | MYELODYSPLASTIC SYNDROME | 1 | CTD_human |
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