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Fusion gene ID: 21547 |
FusionGeneSummary for MED24_SSH2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MED24_SSH2 | Fusion gene ID: 21547 | Hgene | Tgene | Gene symbol | MED24 | SSH2 | Gene ID | 9862 | 85464 |
| Gene name | mediator complex subunit 24 | slingshot protein phosphatase 2 | |
| Synonyms | ARC100|CRSP100|CRSP4|DRIP100|MED5|THRAP4|TRAP100 | SSH-2|SSH-2L | |
| Cytomap | 17q21.1 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mediator of RNA polymerase II transcription subunit 24CRSP complex subunit 4activator-recruited cofactor 100 kDa componentcofactor required for Sp1 transcriptional activation subunit 4cofactor required for Sp1 transcriptional activation, subunit 4, 10 | protein phosphatase Slingshot homolog 2SSH-like protein 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O75448 | Q76I76 | |
| Ensembl transtripts involved in fusion gene | ENST00000394126, ENST00000356271, ENST00000394128, ENST00000394127, ENST00000501516, ENST00000479829, | ENST00000269033, ENST00000540801, ENST00000324677, ENST00000582084, ENST00000590153, ENST00000579954, | |
| Fusion gene scores | * DoF score | 14 X 9 X 8=1008 | 15 X 11 X 8=1320 |
| # samples | 15 | 15 | |
| ** MAII score | log2(15/1008*10)=-2.74846123300404 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/1320*10)=-3.13750352374993 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MED24 [Title/Abstract] AND SSH2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MED24 | GO:0006367 | transcription initiation from RNA polymerase II promoter | 12218053 |
| Hgene | MED24 | GO:0030518 | intracellular steroid hormone receptor signaling pathway | 11867769 |
| Hgene | MED24 | GO:0030521 | androgen receptor signaling pathway | 12218053 |
| Hgene | MED24 | GO:0045893 | positive regulation of transcription, DNA-templated | 10198638 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-B6-A0WV-01A | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000394126 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000394126 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-5UTR | ENST00000394126 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394126 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394126 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394126 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000356271 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000356271 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-5UTR | ENST00000356271 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000356271 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000356271 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000356271 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000394128 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000394128 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-5UTR | ENST00000394128 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394128 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394128 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394128 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| In-frame | ENST00000394127 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| In-frame | ENST00000394127 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-5UTR | ENST00000394127 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394127 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394127 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000394127 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000501516 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| Frame-shift | ENST00000501516 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-5UTR | ENST00000501516 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000501516 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000501516 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5CDS-intron | ENST00000501516 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-3CDS | ENST00000479829 | ENST00000269033 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-3CDS | ENST00000479829 | ENST00000540801 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-5UTR | ENST00000479829 | ENST00000324677 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-intron | ENST00000479829 | ENST00000582084 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-intron | ENST00000479829 | ENST00000590153 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
| 5UTR-intron | ENST00000479829 | ENST00000579954 | MED24 | chr17 | 38209551 | - | SSH2 | chr17 | 28030080 | - |
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FusionProtFeatures for MED24_SSH2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MED24 | SSH2 |
| Component of the Mediator complex, a coactivatorinvolved in the regulated transcription of nearly all RNApolymerase II-dependent genes. Mediator functions as a bridge toconvey information from gene-specific regulatory proteins to thebasal RNA polymerase II transcription machinery. Mediator isrecruited to promoters by direct interactions with regulatoryproteins and serves as a scaffold for the assembly of a functionalpreinitiation complex with RNA polymerase II and the generaltranscription factors. {ECO:0000269|PubMed:12218053,ECO:0000269|PubMed:16595664}. | Protein phosphatase which regulates actin filamentdynamics. Dephosphorylates and activates the actinbinding/depolymerizing factor cofilin, which subsequently binds toactin filaments and stimulates their disassembly. Inhibitoryphosphorylation of cofilin is mediated by LIMK1, which may also bedephosphorylated and inactivated by this protein.{ECO:0000269|PubMed:11832213}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MED24_SSH2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000269033_chr17_28030080_-_1459aa MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQHQRELSNCQRCCPFSTTGK WLIHTKNQPQTEQACRRSPTASPSNVHFTPPRRQHQAGCKTGKYLPESNTLYGSGFNXWXTRHXRKHRPRNGFLLXXQXHLYHGLSFASL ERHANSFGWXWWVQCIDGXQSSHIQTCICAGNVVCTTELTQGLXSRQSAXLLPRQPISHLGELLXEPYQLRSILSQXMECNARCTVPPAR LSSSLHRHTYXTXTNRKANXNQIKGDHDAEGFGEYYIQRDKNRVGNANGVQLAGIQGIYRQXNDSDPWSNGXPYTDIXACVPGLRMECLQ LRGLTEPRGTVYLECHSRDRXLLPRSLXVSXHSGIXXRGNGSPGVLEXHLQIHLXSKETWIXMPCALQNGGESLSLHRDCLCNEGIWLES GPSLXLCERKTNGNQAQPKLHETTGRVSGDLAGKQTAAXQTMEISFRXXPLRPPRTHLQTWARTQQEGYHHLSRPDCXGEDHGESPTHTS CLCGTYGPTRCKSERPVYQRKNDLLGVYFXGISCWTDXGXIKLKXHQWMLIRVLSEXIKISSXQLPCIQSLNSAWTCPRNGQQVSRLNSG RFGDRCTESRHECPPTAYGRIDISTERPPHVPXSXVTKPPTQLPDXNLRFQYRSHXLFXCPREVCGALPRNPVTIFFPFKDGGTGWRKEX ELSTVSGRSSPFQSDSXXPEKQLFEXYSPCIRRIFNGXGTVKGNFRTGQPRHLHAVSLGKCNFSQRNCHXNXVHQSRSWADSTERRHLTQ PMPYTKEEQHPXAAPXEGPDSREQTWTYGARXGLLHSPAXTSQRLRDVQPRRLPNHTLIYSRLGRRGTSXGGTRAPGLRDAPRCQVVPWV CEASHLGVRRALTAGARASWCCPNMYLIVHSXEFKEXFFCGRPSTKREKXXSPPRTFICPQGTRNEQRQREIQWVXGWLTVPFXAECHCS SSQGAGVXPLARSSGGPRVRYWNTAGRSPEGSEDCDSIPGVXNTSSPSSPSQEGRNHXIYPHSYITQSHWAREXNSHQXEERRARAEESE HGKICHCALHTGXKSKQDSGPQPGFSAPPSATSASFFLPXAQQTHXPSNLHPEXPXRQRQQPVHSPGDSSTFCQSYNPFTVCQFGLPASP DYGSPGGLHRAEQHYRXALCRTGXLGRKSGEPSLQWQXGAIXGLPAKXRRPKFNXQTWXQHWGVTGENGPIACSLSTPTXLXXXKHKESQ PQPRCGEGACXRNRVSSGFPGRAHQTIPNEALSFSRQIRLLGPLXRLLTREGACLLXIPSSQTASAFPQNRLRHARDGGPRVPRKPRCPP QPRAHQVFCRTTHNNRVYCAEQASGEAPCAVCQRIWFXSAVFAPQGRTXIDXFXRRPSRATDPGTAVCMPSSRAGRGTPSATRQNSPPXE >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000540801_chr17_28030080_-_1459aa MKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQHQRELSNCQRCCPFSTTGK WLIHTKNQPQTEQACRRSPTASPSNVHFTPPRRQHQAGCKTGKYLPESNTLYGSGFNXWXTRHXRKHRPRNGFLLXXQXHLYHGLSFASL ERHANSFGWXWWVQCIDGXQSSHIQTCICAGNVVCTTELTQGLXSRQSAXLLPRQPISHLGELLXEPYQLRSILSQXMECNARCTVPPAR LSSSLHRHTYXTXTNRKANXNQIKGDHDAEGFGEYYIQRDKNRVGNANGVQLAGIQGIYRQXNDSDPWSNGXPYTDIXACVPGLRMECLQ LRGLTEPRGTVYLECHSRDRXLLPRSLXVSXHSGIXXRGNGSPGVLEXHLQIHLXSKETWIXMPCALQNGGESLSLHRDCLCNEGIWLES GPSLXLCERKTNGNQAQPKLHETTGRVSGDLAGKQTAAXQTMEISFRXXPLRPPRTHLQTWARTQQEGYHHLSRPDCXGEDHGESPTHTS CLCGTYGPTRCKSERPVYQRKNDLLGVYFXGISCWTDXGXIKLKXHQWMLIRVLSEXIKISSXQLPCIQSLNSAWTCPRNGQQVSRLNSG RFGDRCTESRHECPPTAYGRIDISTERPPHVPXSXVTKPPTQLPDXNLRFQYRSHXLFXCPREVCGALPRNPVTIFFPFKDGGTGWRKEX ELSTVSGRSSPFQSDSXXPEKQLFEXYSPCIRRIFNGXGTVKGNFRTGQPRHLHAVSLGKCNFSQRNCHXNXVHQSRSWADSTERRHLTQ PMPYTKEEQHPXAAPXEGPDSREQTWTYGARXGLLHSPAXTSQRLRDVQPRRLPNHTLIYSRLGRRGTSXGGTRAPGLRDAPRCQVVPWV CEASHLGVRRALTAGARASWCCPNMYLIVHSXEFKEXFFCGRPSTKREKXXSPPRTFICPQGTRNEQRQREIQWVXGWLTVPFXAECHCS SSQGAGVXPLARSSGGPRVRYWNTAGRSPEGSEDCDSIPGVXNTSSPSSPSQEGRNHXIYPHSYITQSHWAREXNSHQXEERRARAEESE HGKICHCALHTGXKSKQDSGPQPGFSAPPSATSASFFLPXAQQTHXPSNLHPEXPXRQRQQPVHSPGDSSTFCQSYNPFTVCQFGLPASP DYGSPGGLHRAEQHYRXALCRTGXLGRKSGEPSLQWQXGAIXGLPAKXRRPKFNXQTWXQHWGVTGENGPIACSLSTPTXLXXXKHKESQ PQPRCGEGACXRNRVSSGFPGRAHQTIPNEALSFSRQIRLLGPLXRLLTREGACLLXIPSSQTASAFPQNRLRHARDGGPRVPRKPRCPP QPRAHQVFCRTTHNNRVYCAEQASGEAPCAVCQRIWFXSAVFAPQGRTXIDXFXRRPSRATDPGTAVCMPSSRAGRGTPSATRQNSPPXE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000269033_chr17_28030080_-_4378nt ATGAAGGTGGTCAACCTGAAGCAAGCCATTTTGCAAGCCTGGAAGGAGCGCTGGAGTGACTACCAATGGGCAATCAACATGAAGAAATTC TTTCCTAAAGGAGCCACCTGGGATATTCTCAACCTGGCAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCCCCAATCCTCTCATC TTGTCCTACCTGAAGTATGCCATTAGTTCCCAGCATCAGCGAGAGCTTTCTAACTGTCAAAGGTGCTGCCCTTTTTCTACCACGGGGAAA TGGCTCATCCACACCAAGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCAAGCAATGTTCATTTTACTCCG CCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAGTACTTACCAGAATCGAACACGCTATATGGTAGTGGTTTCAACTAATGGTAG ACAAGACACTGAAGAAAGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCATGGGCTTAGTTTTGCCTCTCTG GAGCGACACGCTAATTCATTTGGATGGTGATGGTGGGTTCAGTGTATCGACGGATAACAGAGTTCACATATTCAAACCTGTATCTGTGCA GGCAATGTGGTCTGCACTACAGAGCTTACACAAGGCTTGTGAAGTCGCCAGAGCGCATAACTACTACCCAGGCAGCCTATTTCTCACTTG GGTGAGTTATTATGAGAGCCATATCAACTCAGATCAATCCTCAGTCAATGAATGGAATGCAATGCAAGATGTACAGTCCCACCGGCCCGA CTCTCCAGCTCTCTTCACCGACATACCTACTGAACGTGAACGAACAGAAAGGCTAATTAAAACCAAATTAAGGGAGATCATGATGCAGAA GGATTTGGAGAATATTACATCCAAAGAGATAAGAACAGAGTTGGAAATGCAAATGGTGTGCAACTTGCGGGAATTCAAGGAATTTATAGA CAATGAAATGATAGTGATCCTTGGTCAAATGGATAGCCCTACACAGATATTTGAGCATGTGTTCCTGGGCTCAGAATGGAATGCCTCCAA CTTAGAGGACTTACAGAACCGAGGGGTACGGTATATCTTGAATGTCACTCGAGAGATAGATAACTTCTTCCCAGGAGTCTTTGAGTATCA TAACATTCGGGTATATGATGAAGAGGCAACGGATCTCCTGGCGTACTGGAATGACACTTACAAATTCATCTCTAAAGCAAAGAAACATGG ATCTAAATGCCTTGTGCACTGCAAAATGGGGGTGAGTCGCTCAGCCTCCACCGTGATTGCCTATGCAATGAAGGAATATGGCTGGAATCT GGACCGAGCCTATGACTATGTGAAAGAAAGACGAACGGTAACCAAGCCCAACCCAAGCTTCATGAGACAACTGGAAGAGTATCAGGGGAT CTTGCTGGCAAGCAAACAGCGGCATAACAAACTATGGAGATCTCATTCAGATAGTGACCTCTCAGACCACCACGAACCCATCTGCAAACC TGGGCTAGAACTCAACAAGAAGGATATCACCACCTCAGCAGACCAGATTGCTGAGGTGAAGACCATGGAGAGTCACCCACCCATACCTCC TGTCTTTGTGGAACATATGGTCCCACAAGATGCAAATCAGAAAGGCCTGTGTACCAAAGAAAGAATGATCTGCTTGGAGTTTACTTCTAG GGAATTTCATGCTGGACAGATTGAGGATGAATTAAACTTAAATGACATCAATGGATGCTCATCAGGGTGTTGTCTGAATGAATCAAAATT TCCTCTTGACAATTGCCATGCATCCAAAGCCTTAATTCAGCCTGGACATGTCCCAGAAATGGCCAACAAGTTTCCAGACTTAACAGTGGA AGATTTGGAGACAGATGCACTGAAAGCAGACATGAATGTCCACCTACTGCCTATGGAAGAATTGACATCTCCACTGAAAGACCCCCCCAT GTCCCCTGATCCTGAGTCACCAAGCCCCCAACCCAGTTGCCAGACTGAAATCTCAGATTTCAGTACAGATCGCATTGACTTTTTTAGTGC CCTAGAGAAGTTTGTGGAGCTCTCCCAAGAAACCCGGTCACGATCTTTTTCCCATTCAAGGATGGAGGAACTGGGTGGAGGAAGGAATGA GAGCTGTCGACTGTCAGTGGTAGAAGTAGCCCCTTCCAAAGTGACAGCTGATGACCAGAGAAGCAGCTCTTTGAGTAATACTCCCCATGC ATCAGAAGAATCTTCAATGGATGAGGAACAGTCAAAGGCAATTTCAGAACTGGTCAGCCCAGACATCTTCATGCAGTCTCACTCGGAAAA TGCAATTTCAGTCAAAGAAATTGTCACTGAAATTGAGTCCATCAGTCAAGGAGTTGGGCAGATTCAACTGAAAGGAGACATCTTACCCAA CCCATGCCATACACCAAAGAAGAACAGCATCCATGAGCTGCTCCTTGAGAGGGCCCAGACTCCAGAGAACAAACCTGGACATATGGAGCA AGATGAGGACTCCTGCACAGCCCAGCCTGAACTAGCCAAAGACTCAGGGATGTGCAACCCAGAAGGCTGCCTAACCACACACTCATCTAT AGCAGACTTGGAAGAAGGGGAACCAGCTGAGGGGGAACAAGAGCTCCAGGGCTCAGGGATGCACCCAGGTGCCAAGTGGTACCCTGGGTC TGTGAGGCGAGCCACCTTGGAGTTCGAAGAGCGCTTACGGCAGGAGCAAGAGCATCATGGTGCTGCCCCAACATGTACCTCATTGTCCAC TCGTAAGAATTCAAAGAATGATTCTTCTGTGGCAGACCTAGCACCAAAAGGGAAAAGTGATGAAGCCCCCCCAGAACATTCATTTGTCCT CAAGGAACCAGAAATGAGCAAAGGCAAAGGGAAATACAGTGGGTCTGAGGCTGGCTCACTGTCCCATTCTGAGCAGAATGCCACTGTTCC AGCTCCCAGGGTGCTGGAGTTTGACCACTTGCCAGATCCTCAGGAGGGCCCAGGGTCAGATACTGGAACACAGCAGGAAGGAGTCCTGAA GGATCTGAGGACTGTGATTCCATACCAGGAGTCTGAAACACAAGCAGTCCCTCTTCCCCTTCCCAAGAGGGTAGAAATCATTGAATATAC CCACATAGTTACATCACCCAATCACACTGGGCCAGGGAGTGAAATAGCCACCAGTGAGAAGAGCGGAGAGCAAGGGCTGAGGAAAGTGAA CATGGAAAAATCTGTCACTGTGCTCTGCACACTGGATGAAAATCTAAACAGGACTCTGGACCCCAACCAGGTTTCTCTGCACCCCCAAGT GCTACCTCTGCCTCATTCTTCCTCCCCTGAGCACAACAGACCCACTGACCATCCAACCTCCATCCTGAGTAGCCCTGAAGACAGAGGCAG CAGCCTGTCCACAGCCCTGGAGACAGCAGCACCTTTTGTCAGTCATACAACCCATTTACTGTCTGCCAGTTTGGATTACCTGCATCCCCA GACTATGGTTCACCTGGAGGGCTTCACAGAGCAGAGCAGCACTACAGATGAGCCCTCTGCAGAACAGGTTAGCTGGGAAGAAAGTCAGGA GAGCCCTCTCTCCAGTGGCAGTGAGGTGCCATATAAGGACTCCCAGCTAAGTAGCGCAGACCTAAGTTTAATTAGCAAACTTGGTGACAA CACTGGGGAGTTACAGGAGAAAATGGACCCATTGCCTGTAGCCTGTCGACTCCCACATAGCTCTAGTAGTGAAAACATAAAGAGTCTCAG CCACAGCCCCGGTGTGGTGAAGGAGCGTGCTAAAGAAATCGAGTCTCGAGTGGTTTTCCAGGCAGGGCTCACCAAACCATCCCAAATGAG GCGCTCAGCTTCTCTCGCCAAATTAGGTTACTTGGACCTCTGTAAAGACTGCTTACCAGAGAGGGAGCCTGCCTCCTGTGAATCCCCTCA TCTCAAACTGCTTCAGCCTTTCCTCAGAACAGACTCAGGCATGCACGCGATGGAGGACCAAGAGTCCCTAGAAAACCCAGGTGCCCCCCA CAACCCAGAGCCCACCAAGTCTTTTGTAGAACAACTCACAACAACAGAGTGTATTGTGCAGAGCAAGCCAGTGGAGAGGCCCCTTGTGCA GTATGCCAAAGAATTTGGTTCTAGTCAGCAGTATTTGCTCCCCAGGGCAGGACTTGAATTGACTAGTTCTGAAGGAGGCCTTCCCGTGCT ACAGACCCAGGGACTGCAGTGTGCATGCCCAGCTCCAGGGCTGGCCGTGGCACCCCGTCAGCAACACGGCAGAACTCACCCCCTTAGGAG >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000540801_chr17_28030080_-_4378nt ATGAAGGTGGTCAACCTGAAGCAAGCCATTTTGCAAGCCTGGAAGGAGCGCTGGAGTGACTACCAATGGGCAATCAACATGAAGAAATTC TTTCCTAAAGGAGCCACCTGGGATATTCTCAACCTGGCAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCCCCAATCCTCTCATC TTGTCCTACCTGAAGTATGCCATTAGTTCCCAGCATCAGCGAGAGCTTTCTAACTGTCAAAGGTGCTGCCCTTTTTCTACCACGGGGAAA TGGCTCATCCACACCAAGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCAAGCAATGTTCATTTTACTCCG CCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAGTACTTACCAGAATCGAACACGCTATATGGTAGTGGTTTCAACTAATGGTAG ACAAGACACTGAAGAAAGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCATGGGCTTAGTTTTGCCTCTCTG GAGCGACACGCTAATTCATTTGGATGGTGATGGTGGGTTCAGTGTATCGACGGATAACAGAGTTCACATATTCAAACCTGTATCTGTGCA GGCAATGTGGTCTGCACTACAGAGCTTACACAAGGCTTGTGAAGTCGCCAGAGCGCATAACTACTACCCAGGCAGCCTATTTCTCACTTG GGTGAGTTATTATGAGAGCCATATCAACTCAGATCAATCCTCAGTCAATGAATGGAATGCAATGCAAGATGTACAGTCCCACCGGCCCGA CTCTCCAGCTCTCTTCACCGACATACCTACTGAACGTGAACGAACAGAAAGGCTAATTAAAACCAAATTAAGGGAGATCATGATGCAGAA GGATTTGGAGAATATTACATCCAAAGAGATAAGAACAGAGTTGGAAATGCAAATGGTGTGCAACTTGCGGGAATTCAAGGAATTTATAGA CAATGAAATGATAGTGATCCTTGGTCAAATGGATAGCCCTACACAGATATTTGAGCATGTGTTCCTGGGCTCAGAATGGAATGCCTCCAA CTTAGAGGACTTACAGAACCGAGGGGTACGGTATATCTTGAATGTCACTCGAGAGATAGATAACTTCTTCCCAGGAGTCTTTGAGTATCA TAACATTCGGGTATATGATGAAGAGGCAACGGATCTCCTGGCGTACTGGAATGACACTTACAAATTCATCTCTAAAGCAAAGAAACATGG ATCTAAATGCCTTGTGCACTGCAAAATGGGGGTGAGTCGCTCAGCCTCCACCGTGATTGCCTATGCAATGAAGGAATATGGCTGGAATCT GGACCGAGCCTATGACTATGTGAAAGAAAGACGAACGGTAACCAAGCCCAACCCAAGCTTCATGAGACAACTGGAAGAGTATCAGGGGAT CTTGCTGGCAAGCAAACAGCGGCATAACAAACTATGGAGATCTCATTCAGATAGTGACCTCTCAGACCACCACGAACCCATCTGCAAACC TGGGCTAGAACTCAACAAGAAGGATATCACCACCTCAGCAGACCAGATTGCTGAGGTGAAGACCATGGAGAGTCACCCACCCATACCTCC TGTCTTTGTGGAACATATGGTCCCACAAGATGCAAATCAGAAAGGCCTGTGTACCAAAGAAAGAATGATCTGCTTGGAGTTTACTTCTAG GGAATTTCATGCTGGACAGATTGAGGATGAATTAAACTTAAATGACATCAATGGATGCTCATCAGGGTGTTGTCTGAATGAATCAAAATT TCCTCTTGACAATTGCCATGCATCCAAAGCCTTAATTCAGCCTGGACATGTCCCAGAAATGGCCAACAAGTTTCCAGACTTAACAGTGGA AGATTTGGAGACAGATGCACTGAAAGCAGACATGAATGTCCACCTACTGCCTATGGAAGAATTGACATCTCCACTGAAAGACCCCCCCAT GTCCCCTGATCCTGAGTCACCAAGCCCCCAACCCAGTTGCCAGACTGAAATCTCAGATTTCAGTACAGATCGCATTGACTTTTTTAGTGC CCTAGAGAAGTTTGTGGAGCTCTCCCAAGAAACCCGGTCACGATCTTTTTCCCATTCAAGGATGGAGGAACTGGGTGGAGGAAGGAATGA GAGCTGTCGACTGTCAGTGGTAGAAGTAGCCCCTTCCAAAGTGACAGCTGATGACCAGAGAAGCAGCTCTTTGAGTAATACTCCCCATGC ATCAGAAGAATCTTCAATGGATGAGGAACAGTCAAAGGCAATTTCAGAACTGGTCAGCCCAGACATCTTCATGCAGTCTCACTCGGAAAA TGCAATTTCAGTCAAAGAAATTGTCACTGAAATTGAGTCCATCAGTCAAGGAGTTGGGCAGATTCAACTGAAAGGAGACATCTTACCCAA CCCATGCCATACACCAAAGAAGAACAGCATCCATGAGCTGCTCCTTGAGAGGGCCCAGACTCCAGAGAACAAACCTGGACATATGGAGCA AGATGAGGACTCCTGCACAGCCCAGCCTGAACTAGCCAAAGACTCAGGGATGTGCAACCCAGAAGGCTGCCTAACCACACACTCATCTAT AGCAGACTTGGAAGAAGGGGAACCAGCTGAGGGGGAACAAGAGCTCCAGGGCTCAGGGATGCACCCAGGTGCCAAGTGGTACCCTGGGTC TGTGAGGCGAGCCACCTTGGAGTTCGAAGAGCGCTTACGGCAGGAGCAAGAGCATCATGGTGCTGCCCCAACATGTACCTCATTGTCCAC TCGTAAGAATTCAAAGAATGATTCTTCTGTGGCAGACCTAGCACCAAAAGGGAAAAGTGATGAAGCCCCCCCAGAACATTCATTTGTCCT CAAGGAACCAGAAATGAGCAAAGGCAAAGGGAAATACAGTGGGTCTGAGGCTGGCTCACTGTCCCATTCTGAGCAGAATGCCACTGTTCC AGCTCCCAGGGTGCTGGAGTTTGACCACTTGCCAGATCCTCAGGAGGGCCCAGGGTCAGATACTGGAACACAGCAGGAAGGAGTCCTGAA GGATCTGAGGACTGTGATTCCATACCAGGAGTCTGAAACACAAGCAGTCCCTCTTCCCCTTCCCAAGAGGGTAGAAATCATTGAATATAC CCACATAGTTACATCACCCAATCACACTGGGCCAGGGAGTGAAATAGCCACCAGTGAGAAGAGCGGAGAGCAAGGGCTGAGGAAAGTGAA CATGGAAAAATCTGTCACTGTGCTCTGCACACTGGATGAAAATCTAAACAGGACTCTGGACCCCAACCAGGTTTCTCTGCACCCCCAAGT GCTACCTCTGCCTCATTCTTCCTCCCCTGAGCACAACAGACCCACTGACCATCCAACCTCCATCCTGAGTAGCCCTGAAGACAGAGGCAG CAGCCTGTCCACAGCCCTGGAGACAGCAGCACCTTTTGTCAGTCATACAACCCATTTACTGTCTGCCAGTTTGGATTACCTGCATCCCCA GACTATGGTTCACCTGGAGGGCTTCACAGAGCAGAGCAGCACTACAGATGAGCCCTCTGCAGAACAGGTTAGCTGGGAAGAAAGTCAGGA GAGCCCTCTCTCCAGTGGCAGTGAGGTGCCATATAAGGACTCCCAGCTAAGTAGCGCAGACCTAAGTTTAATTAGCAAACTTGGTGACAA CACTGGGGAGTTACAGGAGAAAATGGACCCATTGCCTGTAGCCTGTCGACTCCCACATAGCTCTAGTAGTGAAAACATAAAGAGTCTCAG CCACAGCCCCGGTGTGGTGAAGGAGCGTGCTAAAGAAATCGAGTCTCGAGTGGTTTTCCAGGCAGGGCTCACCAAACCATCCCAAATGAG GCGCTCAGCTTCTCTCGCCAAATTAGGTTACTTGGACCTCTGTAAAGACTGCTTACCAGAGAGGGAGCCTGCCTCCTGTGAATCCCCTCA TCTCAAACTGCTTCAGCCTTTCCTCAGAACAGACTCAGGCATGCACGCGATGGAGGACCAAGAGTCCCTAGAAAACCCAGGTGCCCCCCA CAACCCAGAGCCCACCAAGTCTTTTGTAGAACAACTCACAACAACAGAGTGTATTGTGCAGAGCAAGCCAGTGGAGAGGCCCCTTGTGCA GTATGCCAAAGAATTTGGTTCTAGTCAGCAGTATTTGCTCCCCAGGGCAGGACTTGAATTGACTAGTTCTGAAGGAGGCCTTCCCGTGCT ACAGACCCAGGGACTGCAGTGTGCATGCCCAGCTCCAGGGCTGGCCGTGGCACCCCGTCAGCAACACGGCAGAACTCACCCCCTTAGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000269033_chr17_28030080_-_9385nt AAGTGCCAAAATGGCGATGCCTACCACCTAGAACTGGATTGTGCGCTCCATTTCTTTCACCTCAAAGCTGGCCGCCACCGCTGCCACCTG CTCAGAGTGAAATAATGAAGGTGGTCAACCTGAAGCAAGCCATTTTGCAAGCCTGGAAGGAGCGCTGGAGTGACTACCAATGGGCAATCA ACATGAAGAAATTCTTTCCTAAAGGAGCCACCTGGGATATTCTCAACCTGGCAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCC CCAATCCTCTCATCTTGTCCTACCTGAAGTATGCCATTAGTTCCCAGCATCAGCGAGAGCTTTCTAACTGTCAAAGGTGCTGCCCTTTTT CTACCACGGGGAAATGGCTCATCCACACCAAGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCAAGCAATG TTCATTTTACTCCGCCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAGTACTTACCAGAATCGAACACGCTATATGGTAGTGGTT TCAACTAATGGTAGACAAGACACTGAAGAAAGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCATGGGCTTA GTTTTGCCTCTCTGGAGCGACACGCTAATTCATTTGGATGGTGATGGTGGGTTCAGTGTATCGACGGATAACAGAGTTCACATATTCAAA CCTGTATCTGTGCAGGCAATGTGGTCTGCACTACAGAGCTTACACAAGGCTTGTGAAGTCGCCAGAGCGCATAACTACTACCCAGGCAGC CTATTTCTCACTTGGGTGAGTTATTATGAGAGCCATATCAACTCAGATCAATCCTCAGTCAATGAATGGAATGCAATGCAAGATGTACAG TCCCACCGGCCCGACTCTCCAGCTCTCTTCACCGACATACCTACTGAACGTGAACGAACAGAAAGGCTAATTAAAACCAAATTAAGGGAG ATCATGATGCAGAAGGATTTGGAGAATATTACATCCAAAGAGATAAGAACAGAGTTGGAAATGCAAATGGTGTGCAACTTGCGGGAATTC AAGGAATTTATAGACAATGAAATGATAGTGATCCTTGGTCAAATGGATAGCCCTACACAGATATTTGAGCATGTGTTCCTGGGCTCAGAA TGGAATGCCTCCAACTTAGAGGACTTACAGAACCGAGGGGTACGGTATATCTTGAATGTCACTCGAGAGATAGATAACTTCTTCCCAGGA GTCTTTGAGTATCATAACATTCGGGTATATGATGAAGAGGCAACGGATCTCCTGGCGTACTGGAATGACACTTACAAATTCATCTCTAAA GCAAAGAAACATGGATCTAAATGCCTTGTGCACTGCAAAATGGGGGTGAGTCGCTCAGCCTCCACCGTGATTGCCTATGCAATGAAGGAA TATGGCTGGAATCTGGACCGAGCCTATGACTATGTGAAAGAAAGACGAACGGTAACCAAGCCCAACCCAAGCTTCATGAGACAACTGGAA GAGTATCAGGGGATCTTGCTGGCAAGCAAACAGCGGCATAACAAACTATGGAGATCTCATTCAGATAGTGACCTCTCAGACCACCACGAA CCCATCTGCAAACCTGGGCTAGAACTCAACAAGAAGGATATCACCACCTCAGCAGACCAGATTGCTGAGGTGAAGACCATGGAGAGTCAC CCACCCATACCTCCTGTCTTTGTGGAACATATGGTCCCACAAGATGCAAATCAGAAAGGCCTGTGTACCAAAGAAAGAATGATCTGCTTG GAGTTTACTTCTAGGGAATTTCATGCTGGACAGATTGAGGATGAATTAAACTTAAATGACATCAATGGATGCTCATCAGGGTGTTGTCTG AATGAATCAAAATTTCCTCTTGACAATTGCCATGCATCCAAAGCCTTAATTCAGCCTGGACATGTCCCAGAAATGGCCAACAAGTTTCCA GACTTAACAGTGGAAGATTTGGAGACAGATGCACTGAAAGCAGACATGAATGTCCACCTACTGCCTATGGAAGAATTGACATCTCCACTG AAAGACCCCCCCATGTCCCCTGATCCTGAGTCACCAAGCCCCCAACCCAGTTGCCAGACTGAAATCTCAGATTTCAGTACAGATCGCATT GACTTTTTTAGTGCCCTAGAGAAGTTTGTGGAGCTCTCCCAAGAAACCCGGTCACGATCTTTTTCCCATTCAAGGATGGAGGAACTGGGT GGAGGAAGGAATGAGAGCTGTCGACTGTCAGTGGTAGAAGTAGCCCCTTCCAAAGTGACAGCTGATGACCAGAGAAGCAGCTCTTTGAGT AATACTCCCCATGCATCAGAAGAATCTTCAATGGATGAGGAACAGTCAAAGGCAATTTCAGAACTGGTCAGCCCAGACATCTTCATGCAG TCTCACTCGGAAAATGCAATTTCAGTCAAAGAAATTGTCACTGAAATTGAGTCCATCAGTCAAGGAGTTGGGCAGATTCAACTGAAAGGA GACATCTTACCCAACCCATGCCATACACCAAAGAAGAACAGCATCCATGAGCTGCTCCTTGAGAGGGCCCAGACTCCAGAGAACAAACCT GGACATATGGAGCAAGATGAGGACTCCTGCACAGCCCAGCCTGAACTAGCCAAAGACTCAGGGATGTGCAACCCAGAAGGCTGCCTAACC ACACACTCATCTATAGCAGACTTGGAAGAAGGGGAACCAGCTGAGGGGGAACAAGAGCTCCAGGGCTCAGGGATGCACCCAGGTGCCAAG TGGTACCCTGGGTCTGTGAGGCGAGCCACCTTGGAGTTCGAAGAGCGCTTACGGCAGGAGCAAGAGCATCATGGTGCTGCCCCAACATGT ACCTCATTGTCCACTCGTAAGAATTCAAAGAATGATTCTTCTGTGGCAGACCTAGCACCAAAAGGGAAAAGTGATGAAGCCCCCCCAGAA CATTCATTTGTCCTCAAGGAACCAGAAATGAGCAAAGGCAAAGGGAAATACAGTGGGTCTGAGGCTGGCTCACTGTCCCATTCTGAGCAG AATGCCACTGTTCCAGCTCCCAGGGTGCTGGAGTTTGACCACTTGCCAGATCCTCAGGAGGGCCCAGGGTCAGATACTGGAACACAGCAG GAAGGAGTCCTGAAGGATCTGAGGACTGTGATTCCATACCAGGAGTCTGAAACACAAGCAGTCCCTCTTCCCCTTCCCAAGAGGGTAGAA ATCATTGAATATACCCACATAGTTACATCACCCAATCACACTGGGCCAGGGAGTGAAATAGCCACCAGTGAGAAGAGCGGAGAGCAAGGG CTGAGGAAAGTGAACATGGAAAAATCTGTCACTGTGCTCTGCACACTGGATGAAAATCTAAACAGGACTCTGGACCCCAACCAGGTTTCT CTGCACCCCCAAGTGCTACCTCTGCCTCATTCTTCCTCCCCTGAGCACAACAGACCCACTGACCATCCAACCTCCATCCTGAGTAGCCCT GAAGACAGAGGCAGCAGCCTGTCCACAGCCCTGGAGACAGCAGCACCTTTTGTCAGTCATACAACCCATTTACTGTCTGCCAGTTTGGAT TACCTGCATCCCCAGACTATGGTTCACCTGGAGGGCTTCACAGAGCAGAGCAGCACTACAGATGAGCCCTCTGCAGAACAGGTTAGCTGG GAAGAAAGTCAGGAGAGCCCTCTCTCCAGTGGCAGTGAGGTGCCATATAAGGACTCCCAGCTAAGTAGCGCAGACCTAAGTTTAATTAGC AAACTTGGTGACAACACTGGGGAGTTACAGGAGAAAATGGACCCATTGCCTGTAGCCTGTCGACTCCCACATAGCTCTAGTAGTGAAAAC ATAAAGAGTCTCAGCCACAGCCCCGGTGTGGTGAAGGAGCGTGCTAAAGAAATCGAGTCTCGAGTGGTTTTCCAGGCAGGGCTCACCAAA CCATCCCAAATGAGGCGCTCAGCTTCTCTCGCCAAATTAGGTTACTTGGACCTCTGTAAAGACTGCTTACCAGAGAGGGAGCCTGCCTCC TGTGAATCCCCTCATCTCAAACTGCTTCAGCCTTTCCTCAGAACAGACTCAGGCATGCACGCGATGGAGGACCAAGAGTCCCTAGAAAAC CCAGGTGCCCCCCACAACCCAGAGCCCACCAAGTCTTTTGTAGAACAACTCACAACAACAGAGTGTATTGTGCAGAGCAAGCCAGTGGAG AGGCCCCTTGTGCAGTATGCCAAAGAATTTGGTTCTAGTCAGCAGTATTTGCTCCCCAGGGCAGGACTTGAATTGACTAGTTCTGAAGGA GGCCTTCCCGTGCTACAGACCCAGGGACTGCAGTGTGCATGCCCAGCTCCAGGGCTGGCCGTGGCACCCCGTCAGCAACACGGCAGAACT CACCCCCTTAGGAGACTGAAAAAGGCAAATGACAAAAAACGGACAACCAACCCCTTCTATAATACCATGTGATTCTGAGCCTACACATGT GACTTTCTAGAAGAAATGTTTGTAAAAGGGGCAGGTGTAATATGTAAGGAACATGCACTTTATTGGTTAATTTTATAATATTTTGGTCAT TTTACTGTTTCTGGTGCATGCAGGGTTTGGGTGTTTTTCAGTGTGTATGTGTGTGTATATGTAAGGGGAAAGAGAGATTGATCTGGATGG CAAGACCGTTTATCATTTTTTATTTAAAAAAATCAAACCTCAAAAAAGTCATTTTCAGAGAACACCTTTATCAAAGGCAAATTGCTGTTT TTCAGTCAGCTGCCACCTGCTTCTCATTTTGCCCTCTGAGAAAAGGCATGGTTTCTTAATTGAGGGAAGGAAGCAGATTCGGAGGGGTGG AGATAAAGCTGGGGATTGGAGATGTTCCCCTGCCTTTGTGATGATGGTTTGGTTTCCAGACCTGAGGCATCGAATGGGCTAAAGGTCAGC CAGAAGTCAGAGGGCTCTCAGCCTTCATCCAGCCGCAGCCCTTTAGAGTTCCTGAAGGAGGCAGGTTCCGCTTTGCTTTAAAAGAGGGTC TTCCGGTGTTCCAGAGTGTATCGTTACAGTAAGACATGATAATGGCCGGCTCTGCAAATTTATCATATAGTTTTTTTCCCAAGAAAATTA TTTTTGAAATTAAAACAGGACCCCAAATGAAATCCAAGTGGTCTTCTGTAGAGGAAAGCATGATAAGAGGAGGAAGACATAAAGTTGGGG GTGGAGAGGCTGCTGCCCAGAAACTGCTGGGTTGGTGGGATCCACACAGATGGGCATCTTGGCTCTCCCTGCCAGAAAAATGTGCTCTGC AGTGTCCTCCCAACTGAAAACAACAGTGACATGTTTGAAAAGCAGCAATCGAAAGTCAGTGTGTTCTTGTAAAATGAATATGTATGTAGG GTTTTAACCCTTCCATTACTTGAATAATTCTTTGGGCCTTCTGAGTTTAATGGCCATATTTTCTTCCAGTTTATTTTCCTTCCCCATGCT GTTGTCCCCATGCTGCCTATTTTTTTAAATTTCATAGATTATATTTGAATTGTTACATATGTTTAACATCCATTGAATGCAACGTTTTAT TTTTGGTATTATCACTGTTAACACTTTTTTTTCCTTTTCCTGGAAGGTTTGTCATTTCTCTAAAGTTTGTACACAGTATTTATGTACATA ATATTGTCACTGTCTTAGTGTCTTGTTCATGTTGTAGGGTAATTTTGATTTATTCTTTTTAAGAAGGAGTAGAGTTGCAACTGGAAAACA CAGACACCAGAAATGAAAGTGTTGGGTGTTGATAGGAATCTGTACAATATGTTGATGGTGGCTGTAGTTGTTTAAATGGAGACTTCCAAT CACCAGCTCCTGCCAAATTATGCATTAGTAACTTTTTCCTCAGAGACACCCCTAAAGGCTCCCATTAGGTCACAGCGTGACTGAAAGCTG ATTTCTCTGTGAGACTGAAATCCCAGAACATTGTTTGCCAGTATCTCAACCACAGCCAGGAAGTATATGTGAGTTGCCCAGAGTGGAAGC TCCTAGTAGAGGCTGAAGGCCACAGGGGAGGCCTCAGCCAGGGGCAAGTGCCCACAGTGACTCCATTTAGGATGCTGTCGTTTTGCTACT GTTGTGGAGATCCTTAACGCAGCAGCGCCTGTCATAAACAAGCCTCTTGTAGCTTCTTACAGAAAACAGATTTAGTCTAGCATGAAACAC CTCTGCATCTCATTGAAACTGAAGAGGCTTGCAGATTTGCTTTCGTTGATGTCCACGTTACTGAGGATTGACTGAGTATAGACTGGAGAC AGGTTTTTGGCTTATCACAGCACTGAGGAAAATACAAATGCACAGACTGTCAGCATGATGTCAGAGGCCAGAGTTTGGTGGGGGCAGATG GCAGGGCGACCCAAAAGATGCAGAAAAGGTAGACTGGGGCCACTGGGTCTTAAGAGGAGCTGTGAAGTTGTGTGGAAGCCAAGGCTGGGT CTGACATCCCTGCCAGGAAGCAGGTTGGACAGAAACCACTTGCTAAAAGCGTCTCTATGGTGCAGTGATTATGTGTACCCTGTGCTGTTG CTCAGTAGTCTCCTTGAATGTTCAAGTATCTCATCCACTCAGTTTTGTGATTCCTGGATATTTGTGTGTTGTAAAGTGTTTTGTTAGGTG GTATGAACCAATGTGAGGAGGCTTGAGACAGGGTTATGGATTTCCAGAGCTCTTCCATGTAGAATACCCTGCCTTCTTGAAGCAGTTCCA CCACCAATATGATGGGGAAGGGCAGGAACTTATGGCAGGGTGGGGAGAGGGTTTGCCTGGAAGTTAAGAGAGTGGCATCCACTTGTGGTA ACCCCTTACGATGATGACATCCCACACACTAAGAGGTACAAGCAGGACCAAAGTTTTGGACTGTTCCCTCTTCTCCCCTCCACTGTGTTT AATGTTCACTCACTGCATTAAATAACAACAAAGATGGGACAAAACCCACTAATACTGTGGGGAAAAAAAATTTTCAAGAGCAGAGGAAAG TCTTTCTGCCTTTTTATAATTACTTTTTTTATCATTTAATTTACCTGCCTAAATAAACATCTTCTACAGAATATCTGTCATTCAACCATG CCAAGGAGTTTGTGCCAGCCTTTTCAGACTCCCAGAATTGGGTGTTCCTGGGTTATTTACATAGCTGAGCAGTGTCCAGGGGAGGTGCGC AGTGAACTGTCAAGGACTTTCCAGACTGTCTTCTCTTCAGACTTTTATAATCTCCAGTGGCATCTTTCCCTTTTCTTTTGTTCATGACCT GACCTGAAGCAGCAGATTTGATAGACTGGCAAAGATGAATAGGAAAAACTTTGACTCTTGCCCAGTGCCTGCCTGCCTCTCTCTCTCTCC TCTCTCTCTCTCTCTTTTTAAACCACCATAGACTCTCACTTATTTTGGAGGAGTGTATGTGCATGTGTACACATATGTACATATATAAAA ACAGTTGATGTTTTGGTGTATGGGGTAAAAGCCCCAGGAGCATACAGAACTTGAGCTGAACCTGGTCAGTAGAAAGGGAAACCCCAACCC TTTCTTGATTTTTGGAGACACCCAGGACTAATGGATACTGTAGTAGACATGTAGTACTATAGTACCGTAATATTCATCTCTCCTCATTTT AGTTGCCTTTCAGATTCTAAATGTTTGGGATCATTCCTATCATCTTAGTCTCTTCAGGATCTTTAGTATTTTCCTGGTTCTGAGGAGGCT TGAGACAGGGTTATGGATTTCCTTGTTCTGTGTCTTTATCCCTACTGATAGTTCCTCTTTCTCATTTTGCAAACTACCCAGAGCTCCAAG GACAGCCTGAAGATCTCAGTGCCTCAGGCTCTGAGGTACTCTGCTCACAGGCCCCAGACAGATGCTGTTGGGTAAACTCAAAGCTTCCTA TGAGAAGCTTCTGAGATGTAGCAGGTCACAGAAGTGTTCACCTGTTTCATCTGAGGATTTCAGTTCTGAAGTGATCTAGGCATGTTTGGT AAAAATGTTTTTGTGAGAGTTCTTTTTTTAAGAAAGCATTATGCAAAAAGTCACTTTTAAGGGCATTTAAAAATTTTTAAGTAAAGCCAT TCTTTGGCTTTTTTGGACTATTTGTGGATACTTTGTTTACATTTTGAATATTAAAATGTGCATCATCTTGTCGGCCATGCAGTCCTGCAG GCATCAGTGCCCTGGCTGTCCTGTGAGTCCTCATGCAGAGCAGGGCCATCATGGTCAGCCCTTGTGAGTAAGTGGGTATACGCTGAAGCT GACTTCCGTCTGTGTCCTGCCCTCCCATCCAGCACTCTCTATGGAAATAGTTGTCATTTCCTCAGTGATGGTGTGTCTTATAGTGATGGT TGTAATGGTGAATGGCTAGTGTCATTTTGTTTAATTTTGTTTTGCTTTTTGATGGTGGATAAGATGAAATTTTAGCTGTTTCAGCATCAA TCCAACTTAAAAGCATCTTGGACTTTGTTTTCCCTTCCAAACTAAAAGATCAAGGCATGTATTAGACACAAGCATATTTGCTGCCTCAAC TCCTCTGACACCCATATTAGGAAAAGGCCTGCCACCAAAGCAGGAAGCTGCACACTCCTAACCCTTCTCCCAGGGTGTGGGGTCCCTTGA CGTCATGAAGAGCTATTGCAAGGTGCTTCTGTACTTTTCCAGCCTGGAAATGGAGGGTGACTGGCCCTGGCTCCTGCTATGAGAAGATAA CCAGCCTCATTTTCTCAGTGCCCCAGAGGTCTAGGATAGGATTTCTAAACTGGAATCATCCTTAATCACCTTGAAGATCCCTTAAGAGGC ATTTGACTGGTGCTGCCGTCTGTGTCCTCAAAGCAATGCTGGTGGCAGCGTCCTGTGTACACATGCAGAGCTAATACCCAAACTAAAAAC TGGGTAACTGGCCCTGAAGTGCTTCCCAATCAGTAAGCCCACAGGGAAATGTTTGATTTTTATGTTCTGTTGGATTTTGGTTTGCTTGGC ATATCTAAAGGTGCCTTTACTTTTCTTTTTTTTTTTTTTTCTTTCTGCTTTGTTTTGTAGGACTTGTTCTAACATGGAAAACAAGTCCAG AAGACTCTCCTCTGACTGTTACCTTTGCCCCAAGCCACCCCAAACTTTTATGCTCATGTTTTATTAAAGCAGGTGCTCCCTGGAATCTCT GGGACATTTTTGAGGCATTTGAAGCAGAATATAGAGTGGTCTCATCTCCTTCCTTAATCTTCCTGGTGGTTGGGATGTTCCACTTGTATC ATAGATTTTTTTATTACAGATATGCTCCACTGTTTTTAAATGTGAACTTGTGCGCAAATGTGCAGATTCAATGTTCTTGTTACAGATTGA >In-frame_MED24_ENST00000394127_chr17_38209551_-_SSH2_ENST00000540801_chr17_28030080_-_4574nt AAGTGCCAAAATGGCGATGCCTACCACCTAGAACTGGATTGTGCGCTCCATTTCTTTCACCTCAAAGCTGGCCGCCACCGCTGCCACCTG CTCAGAGTGAAATAATGAAGGTGGTCAACCTGAAGCAAGCCATTTTGCAAGCCTGGAAGGAGCGCTGGAGTGACTACCAATGGGCAATCA ACATGAAGAAATTCTTTCCTAAAGGAGCCACCTGGGATATTCTCAACCTGGCAGATGCGTTACTAGAGCAGGCCATGATTGGACCATCCC CCAATCCTCTCATCTTGTCCTACCTGAAGTATGCCATTAGTTCCCAGCATCAGCGAGAGCTTTCTAACTGTCAAAGGTGCTGCCCTTTTT CTACCACGGGGAAATGGCTCATCCACACCAAGAATCAGCCACAGACGGAACAAGCATGCAGGCGATCTCCAACAGCATCTCCAAGCAATG TTCATTTTACTCCGCCCAGAAGACAACATCAGGCTGGCTGTAAGACTGGAAAGTACTTACCAGAATCGAACACGCTATATGGTAGTGGTT TCAACTAATGGTAGACAAGACACTGAAGAAAGCATCGTCCTAGGAATGGATTTCTCCTCTAATGACAGTAGCACTTGTACCATGGGCTTA GTTTTGCCTCTCTGGAGCGACACGCTAATTCATTTGGATGGTGATGGTGGGTTCAGTGTATCGACGGATAACAGAGTTCACATATTCAAA CCTGTATCTGTGCAGGCAATGTGGTCTGCACTACAGAGCTTACACAAGGCTTGTGAAGTCGCCAGAGCGCATAACTACTACCCAGGCAGC CTATTTCTCACTTGGGTGAGTTATTATGAGAGCCATATCAACTCAGATCAATCCTCAGTCAATGAATGGAATGCAATGCAAGATGTACAG TCCCACCGGCCCGACTCTCCAGCTCTCTTCACCGACATACCTACTGAACGTGAACGAACAGAAAGGCTAATTAAAACCAAATTAAGGGAG ATCATGATGCAGAAGGATTTGGAGAATATTACATCCAAAGAGATAAGAACAGAGTTGGAAATGCAAATGGTGTGCAACTTGCGGGAATTC AAGGAATTTATAGACAATGAAATGATAGTGATCCTTGGTCAAATGGATAGCCCTACACAGATATTTGAGCATGTGTTCCTGGGCTCAGAA TGGAATGCCTCCAACTTAGAGGACTTACAGAACCGAGGGGTACGGTATATCTTGAATGTCACTCGAGAGATAGATAACTTCTTCCCAGGA GTCTTTGAGTATCATAACATTCGGGTATATGATGAAGAGGCAACGGATCTCCTGGCGTACTGGAATGACACTTACAAATTCATCTCTAAA GCAAAGAAACATGGATCTAAATGCCTTGTGCACTGCAAAATGGGGGTGAGTCGCTCAGCCTCCACCGTGATTGCCTATGCAATGAAGGAA TATGGCTGGAATCTGGACCGAGCCTATGACTATGTGAAAGAAAGACGAACGGTAACCAAGCCCAACCCAAGCTTCATGAGACAACTGGAA GAGTATCAGGGGATCTTGCTGGCAAGCAAACAGCGGCATAACAAACTATGGAGATCTCATTCAGATAGTGACCTCTCAGACCACCACGAA CCCATCTGCAAACCTGGGCTAGAACTCAACAAGAAGGATATCACCACCTCAGCAGACCAGATTGCTGAGGTGAAGACCATGGAGAGTCAC CCACCCATACCTCCTGTCTTTGTGGAACATATGGTCCCACAAGATGCAAATCAGAAAGGCCTGTGTACCAAAGAAAGAATGATCTGCTTG GAGTTTACTTCTAGGGAATTTCATGCTGGACAGATTGAGGATGAATTAAACTTAAATGACATCAATGGATGCTCATCAGGGTGTTGTCTG AATGAATCAAAATTTCCTCTTGACAATTGCCATGCATCCAAAGCCTTAATTCAGCCTGGACATGTCCCAGAAATGGCCAACAAGTTTCCA GACTTAACAGTGGAAGATTTGGAGACAGATGCACTGAAAGCAGACATGAATGTCCACCTACTGCCTATGGAAGAATTGACATCTCCACTG AAAGACCCCCCCATGTCCCCTGATCCTGAGTCACCAAGCCCCCAACCCAGTTGCCAGACTGAAATCTCAGATTTCAGTACAGATCGCATT GACTTTTTTAGTGCCCTAGAGAAGTTTGTGGAGCTCTCCCAAGAAACCCGGTCACGATCTTTTTCCCATTCAAGGATGGAGGAACTGGGT GGAGGAAGGAATGAGAGCTGTCGACTGTCAGTGGTAGAAGTAGCCCCTTCCAAAGTGACAGCTGATGACCAGAGAAGCAGCTCTTTGAGT AATACTCCCCATGCATCAGAAGAATCTTCAATGGATGAGGAACAGTCAAAGGCAATTTCAGAACTGGTCAGCCCAGACATCTTCATGCAG TCTCACTCGGAAAATGCAATTTCAGTCAAAGAAATTGTCACTGAAATTGAGTCCATCAGTCAAGGAGTTGGGCAGATTCAACTGAAAGGA GACATCTTACCCAACCCATGCCATACACCAAAGAAGAACAGCATCCATGAGCTGCTCCTTGAGAGGGCCCAGACTCCAGAGAACAAACCT GGACATATGGAGCAAGATGAGGACTCCTGCACAGCCCAGCCTGAACTAGCCAAAGACTCAGGGATGTGCAACCCAGAAGGCTGCCTAACC ACACACTCATCTATAGCAGACTTGGAAGAAGGGGAACCAGCTGAGGGGGAACAAGAGCTCCAGGGCTCAGGGATGCACCCAGGTGCCAAG TGGTACCCTGGGTCTGTGAGGCGAGCCACCTTGGAGTTCGAAGAGCGCTTACGGCAGGAGCAAGAGCATCATGGTGCTGCCCCAACATGT ACCTCATTGTCCACTCGTAAGAATTCAAAGAATGATTCTTCTGTGGCAGACCTAGCACCAAAAGGGAAAAGTGATGAAGCCCCCCCAGAA CATTCATTTGTCCTCAAGGAACCAGAAATGAGCAAAGGCAAAGGGAAATACAGTGGGTCTGAGGCTGGCTCACTGTCCCATTCTGAGCAG AATGCCACTGTTCCAGCTCCCAGGGTGCTGGAGTTTGACCACTTGCCAGATCCTCAGGAGGGCCCAGGGTCAGATACTGGAACACAGCAG GAAGGAGTCCTGAAGGATCTGAGGACTGTGATTCCATACCAGGAGTCTGAAACACAAGCAGTCCCTCTTCCCCTTCCCAAGAGGGTAGAA ATCATTGAATATACCCACATAGTTACATCACCCAATCACACTGGGCCAGGGAGTGAAATAGCCACCAGTGAGAAGAGCGGAGAGCAAGGG CTGAGGAAAGTGAACATGGAAAAATCTGTCACTGTGCTCTGCACACTGGATGAAAATCTAAACAGGACTCTGGACCCCAACCAGGTTTCT CTGCACCCCCAAGTGCTACCTCTGCCTCATTCTTCCTCCCCTGAGCACAACAGACCCACTGACCATCCAACCTCCATCCTGAGTAGCCCT GAAGACAGAGGCAGCAGCCTGTCCACAGCCCTGGAGACAGCAGCACCTTTTGTCAGTCATACAACCCATTTACTGTCTGCCAGTTTGGAT TACCTGCATCCCCAGACTATGGTTCACCTGGAGGGCTTCACAGAGCAGAGCAGCACTACAGATGAGCCCTCTGCAGAACAGGTTAGCTGG GAAGAAAGTCAGGAGAGCCCTCTCTCCAGTGGCAGTGAGGTGCCATATAAGGACTCCCAGCTAAGTAGCGCAGACCTAAGTTTAATTAGC AAACTTGGTGACAACACTGGGGAGTTACAGGAGAAAATGGACCCATTGCCTGTAGCCTGTCGACTCCCACATAGCTCTAGTAGTGAAAAC ATAAAGAGTCTCAGCCACAGCCCCGGTGTGGTGAAGGAGCGTGCTAAAGAAATCGAGTCTCGAGTGGTTTTCCAGGCAGGGCTCACCAAA CCATCCCAAATGAGGCGCTCAGCTTCTCTCGCCAAATTAGGTTACTTGGACCTCTGTAAAGACTGCTTACCAGAGAGGGAGCCTGCCTCC TGTGAATCCCCTCATCTCAAACTGCTTCAGCCTTTCCTCAGAACAGACTCAGGCATGCACGCGATGGAGGACCAAGAGTCCCTAGAAAAC CCAGGTGCCCCCCACAACCCAGAGCCCACCAAGTCTTTTGTAGAACAACTCACAACAACAGAGTGTATTGTGCAGAGCAAGCCAGTGGAG AGGCCCCTTGTGCAGTATGCCAAAGAATTTGGTTCTAGTCAGCAGTATTTGCTCCCCAGGGCAGGACTTGAATTGACTAGTTCTGAAGGA GGCCTTCCCGTGCTACAGACCCAGGGACTGCAGTGTGCATGCCCAGCTCCAGGGCTGGCCGTGGCACCCCGTCAGCAACACGGCAGAACT CACCCCCTTAGGAGACTGAAAAAGGCAAATGACAAAAAACGGACAACCAACCCCTTCTATAATACCATGTGATTCTGAGCCTACACATGT |
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FusionGenePPI for MED24_SSH2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MED24 | MED10, MED9, MED29, MED19, MED28, MED26, CDK8, THRA, VDR, PPARA, PPARG, RXRA, MED1, HNF4A, ESR1, ESR2, MED30, BRD4, RPAP2, AR, PARP1, SMAD1, SMAD2, SMAD3, TRRAP, SREBF1, MED12, MED18, ZC3H13, TRIP4, OBFC1, QKI, TRA, MED14, GSK3B, TNFSF11, RPS6KA6, CTDP1, APP, MED13, MED8, MED16, MED17, MED4, MED11, MED21, MED22, PPP6R1, TFIP11, FBXW7, EPAS1, CDK19, MED7, CCNC, NR1I3, TCL1B, MED15, MED20, MED23, MED6, MED25, MED27, KPNB1, XRCC3, EMC2, PPP4R1, ZWINT, KIFAP3, MMGT1, SUCO, LMO2 | SSH2 | ACTB, ELAVL1, BAG3, XPO1, CAPZA2, DBN1, FLNA, MYH9, PPP1CB, IQGAP1, KIF3A, SYNPO, LIMA1, ANLN, MYO19, MYO18A, GAN, FBXW7, MYO1D, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MED24_SSH2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MED24_SSH2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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