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Fusion gene ID: 21310 |
FusionGeneSummary for MCM6_RAB3GAP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MCM6_RAB3GAP1 | Fusion gene ID: 21310 | Hgene | Tgene | Gene symbol | MCM6 | RAB3GAP1 | Gene ID | 4175 | 22930 |
| Gene name | minichromosome maintenance complex component 6 | RAB3 GTPase activating protein catalytic subunit 1 | |
| Synonyms | MCG40308|Mis5|P105MCM | P130|RAB3GAP|RAB3GAP130|WARBM1 | |
| Cytomap | 2q21.3 | 2q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA replication licensing factor MCM6MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe)minichromosome maintenance deficient (mis5, S. pombe) 6 | rab3 GTPase-activating protein catalytic subunitRAB3 GTPase activating protein subunit 1 (catalytic)RAB3 GTPase-activating protein 130 kDa subunitrab3-GAP p130 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q14566 | Q15042 | |
| Ensembl transtripts involved in fusion gene | ENST00000264156, ENST00000492091, | ENST00000264158, ENST00000539493, ENST00000442034, ENST00000487003, ENST00000425393, | |
| Fusion gene scores | * DoF score | 3 X 2 X 3=18 | 2 X 3 X 2=12 |
| # samples | 3 | 3 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: MCM6 [Title/Abstract] AND RAB3GAP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RAB3GAP1 | GO:0043087 | regulation of GTPase activity | 10859313 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | CESC | TCGA-EK-A2R7-01A | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264156 | ENST00000264158 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| In-frame | ENST00000264156 | ENST00000539493 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| In-frame | ENST00000264156 | ENST00000442034 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5CDS-3UTR | ENST00000264156 | ENST00000487003 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5CDS-intron | ENST00000264156 | ENST00000425393 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5UTR-3CDS | ENST00000492091 | ENST00000264158 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5UTR-3CDS | ENST00000492091 | ENST00000539493 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5UTR-3CDS | ENST00000492091 | ENST00000442034 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5UTR-3UTR | ENST00000492091 | ENST00000487003 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
| 5UTR-intron | ENST00000492091 | ENST00000425393 | MCM6 | chr2 | 136622583 | - | RAB3GAP1 | chr2 | 135887565 | + |
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FusionProtFeatures for MCM6_RAB3GAP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MCM6 | RAB3GAP1 |
| Acts as component of the MCM2-7 complex (MCM complex)which is the putative replicative helicase essential for 'once percell cycle' DNA replication initiation and elongation ineukaryotic cells. The active ATPase sites in the MCM2-7 ring areformed through the interaction surfaces of two neighboringsubunits such that a critical structure of a conserved argininefinger motif is provided in trans relative to the ATP-binding siteof the Walker A box of the adjacent subunit. The six ATPase activesites, however, are likely to contribute differentially to thecomplex helicase activity. {ECO:0000269|PubMed:9305914}. | Probable catalytic subunit of a GTPase activatingprotein that has specificity for Rab3 subfamily (RAB3A, RAB3B,RAB3C and RAB3D). Rab3 proteins are involved in regulatedexocytosis of neurotransmitters and hormones. Specificallyconverts active Rab3-GTP to the inactive form Rab3-GDP. Requiredfor normal eye and brain development. May participate inneurodevelopmental processes such as proliferation, migration anddifferentiation before synapse formation, and non-synapticvesicular release of neurotransmitters.{ECO:0000269|PubMed:10859313, ECO:0000269|PubMed:9030515}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MCM6 | chr2:136622583 | chr2:135887565 | ENST00000264156 | - | 7 | 17 | 346_553 | 359 | 822 | Domain | Note=MCM |
| Hgene | >MCM6 | chr2:136622583 | chr2:135887565 | ENST00000264156 | - | 7 | 17 | 528_531 | 359 | 822 | Motif | Note=Arginine finger |
| Hgene | >MCM6 | chr2:136622583 | chr2:135887565 | ENST00000264156 | - | 7 | 17 | 396_403 | 359 | 822 | Nucleotide binding | ATP |
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FusionGeneSequence for MCM6_RAB3GAP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000264158_chr2_135887565_+_1017aa MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYL CRALKTFVKDRKEIPLAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRV SGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG DFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLF PDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGP PDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEEL KGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMES FKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPAD LARHLLPCVIHAAVLKVKEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKE DLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRPAPYSKAL >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000539493_chr2_135887565_+_1015aa MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYL CRALKTFVKDRKEIPLAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRV SGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG DFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLF PDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGP PDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEEL KGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMES FKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPAD LARHLLPCVIHAAVLKVKEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKE DLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRPAPYSKAL >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000442034_chr2_135887565_+_1024aa MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYL CRALKTFVKDRKEIPLAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNIC RNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRV SGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHG DFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLF PDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGP PDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEEL KGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMES FKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPAD LARHLLPCVIHAAVLKVKEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKE DLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRLTESSDEAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000264158_chr2_135887565_+_3051nt ATGGACCTCGCGGCGGCAGCGGAGCCGGGCGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTC CTGGACTTCTTGGAGGAGTTTCAGAGCAGCGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACA TTGGTTGTGAGTTTTGTGGACCTGGAACAATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTG TGTCGGGCCTTGAAAACATTCGTCAAAGACCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGA CACAAGATTCGAGAGCTCACCTCATCCAGAATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAG CTTGTGAGCGGAACTTTTCTGTGCTTGGACTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGC CGAAATCCAGTTTGTGCCAACAGGAGGAGATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAG ACCCAAGCTGAGCTTCCTCGAGGGAGTATCCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGAC AAGTGTGACTTTACAGGGACACTGATTGTTGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTC AGTGGTGTTGATGGATATGAGACAGAAGGCATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCC TGCTGTGTTGCGCCAACCAACCCAAGGTTTGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACT GTGAAAGAATGGGAGAAAGTGTTTGAGATGAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGT GATTTTGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAA GAAACTGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACAC ACTGCAAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTC CCTGATGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTAC AATCAGTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAA GGAGTGGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCC CCAGATCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAG ACAAGTGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGAT AAGGAAAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTT AAAGGAAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAA CTTACACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCT GAAGTTTTAGCTAAATTAGGTACATCGGCAGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCT TTTAAGGCAGCTAATCCAGGTTGCTCCCTGGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAA AAGGGCAATGTGGTGCTGAAAGGAGAACTGAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCA ATTCCTGCTAGAAGGCAAAGGAGACTCTTTGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGAC CTTGCTCGGCACCTGTTACCTTGTGTGATTCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAG AAGATCATAAAGCAGATAATATCCCATTCCAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAG ATTACTAATGTGGAAGCTCTCATTGCCAGAGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAA GATCTTGAAAGGTTTGTGAGTTGCCTGCTGGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCAC AAGCTGTTTGTGAATGCCCAGAGGGCTGCAGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCAGAGGAAAGAAGGCAG AACTCCGTGTCAGACTTCCCACCCCCTGCTGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTG >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000539493_chr2_135887565_+_3045nt ATGGACCTCGCGGCGGCAGCGGAGCCGGGCGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTC CTGGACTTCTTGGAGGAGTTTCAGAGCAGCGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACA TTGGTTGTGAGTTTTGTGGACCTGGAACAATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTG TGTCGGGCCTTGAAAACATTCGTCAAAGACCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGA CACAAGATTCGAGAGCTCACCTCATCCAGAATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAG CTTGTGAGCGGAACTTTTCTGTGCTTGGACTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGC CGAAATCCAGTTTGTGCCAACAGGAGGAGATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAG ACCCAAGCTGAGCTTCCTCGAGGGAGTATCCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGAC AAGTGTGACTTTACAGGGACACTGATTGTTGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTC AGTGGTGTTGATGGATATGAGACAGAAGGCATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCC TGCTGTGTTGCGCCAACCAACCCAAGGTTTGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACT GTGAAAGAATGGGAGAAAGTGTTTGAGATGAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGT GATTTTGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAA GAAACTGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACAC ACTGCAAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTC CCTGATGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTAC AATCAGTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAA GGAGTGGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCC CCAGATCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAG ACAAGTGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGAT AAGGAAAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTT AAAGGAAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAA CTTACACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCT GAAGTTTTAGCTAAATTAGGTACATCGGCAGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCT TTTAAGGCAGCTAATCCAGGTTGCTCCCTGGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAA AAGGGCAATGTGGTGCTGAAAGGAGAACTGAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCA ATTCCTGCTAGAAGGCAAAGGAGACTCTTTGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGAC CTTGCTCGGCACCTGTTACCTTGTGTGATTCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAG AAGATCATAAAGCAGATAATATCCCATTCCAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAG ATTACTAATGTGGAAGCTCTCATTGCCAGAGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAA GATCTTGAAAGGTTTGTGAGTTGCCTGCTGGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCAC AAGCTGTTTGTGAATGCCCAGAGGGCTGCAGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCAGAGGAAAGAAGGCAG AACTCCGTGTCAGACTTCCCACCCCCTGCTGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTG >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000442034_chr2_135887565_+_3072nt ATGGACCTCGCGGCGGCAGCGGAGCCGGGCGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTC CTGGACTTCTTGGAGGAGTTTCAGAGCAGCGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACA TTGGTTGTGAGTTTTGTGGACCTGGAACAATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTG TGTCGGGCCTTGAAAACATTCGTCAAAGACCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGA CACAAGATTCGAGAGCTCACCTCATCCAGAATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAG CTTGTGAGCGGAACTTTTCTGTGCTTGGACTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGC CGAAATCCAGTTTGTGCCAACAGGAGGAGATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAG ACCCAAGCTGAGCTTCCTCGAGGGAGTATCCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGAC AAGTGTGACTTTACAGGGACACTGATTGTTGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTC AGTGGTGTTGATGGATATGAGACAGAAGGCATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCC TGCTGTGTTGCGCCAACCAACCCAAGGTTTGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACT GTGAAAGAATGGGAGAAAGTGTTTGAGATGAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGT GATTTTGTCACTGAATTTTTTAAAATTTGCCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAA GAAACTGCTGATATAACTCATGCTTTGTCAAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACAC ACTGCAAAGAAGAAAATCCGAAAACACAGAGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTC CCTGATGCTGTTTCTGAGAAACCATTAGATGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTAC AATCAGTTCAAGTCTGCACCATCTGACAGTTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAA GGAGTGGCACACCTCTGGCAGGAATTTGTTCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCC CCAGATCTGAGGTGTTGTTTACTGCATCAGAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAG ACAAGTGCTTCAGATGTCACTAATATATATCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGAT AAGGAAAAGGGAGAGGTAGGAAAATCTTGGGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTT AAAGGAAATGGACAAGAGAGTGGCAAGAAAGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAA CTTACACTGCTGCATAATGGAGAACCTCTCTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCT GAAGTTTTAGCTAAATTAGGTACATCGGCAGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCT TTTAAGGCAGCTAATCCAGGTTGCTCCCTGGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAA AAGGGCAATGTGGTGCTGAAAGGAGAACTGAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCA ATTCCTGCTAGAAGGCAAAGGAGACTCTTTGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGAC CTTGCTCGGCACCTGTTACCTTGTGTGATTCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAG AAGATCATAAAGCAGATAATATCCCATTCCAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAG ATTACTAATGTGGAAGCTCTCATTGCCAGAGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAA GATCTTGAAAGGTTTGTGAGTTGCCTGCTGGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCAC AAGCTGTTTGTGAATGCCCAGAGGCTGACTGAATCTTCTGATGAGGCTGCAGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGC TCCCCAGAGGAAAGAAGGCAGAACTCCGTGTCAGACTTCCCACCCCCTGCTGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCT GCTCCCTACTCCAAAGCTCTGCCTCAGCGGATGTACAGTGTTCTCACCAAAGAGGACTTTAGACTTGCAGGTGCCTTTTCATCAGATACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000264158_chr2_135887565_+_5037nt GGAAAAAAGCGACTTGTGGCGGTCGAGCGTGGCGCAGGCGAATCCTCGGCACTAAGCAAATATGGACCTCGCGGCGGCAGCGGAGCCGGG CGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTCCTGGACTTCTTGGAGGAGTTTCAGAGCAG CGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACATTGGTTGTGAGTTTTGTGGACCTGGAACA ATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTGTGTCGGGCCTTGAAAACATTCGTCAAAGA CCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGACACAAGATTCGAGAGCTCACCTCATCCAG AATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAGCTTGTGAGCGGAACTTTTCTGTGCTTGGA CTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGCCGAAATCCAGTTTGTGCCAACAGGAGGAG ATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAGACCCAAGCTGAGCTTCCTCGAGGGAGTAT CCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGACAAGTGTGACTTTACAGGGACACTGATTGT TGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTCAGTGGTGTTGATGGATATGAGACAGAAGG CATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCCTGCTGTGTTGCGCCAACCAACCCAAGGTT TGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACTGTGAAAGAATGGGAGAAAGTGTTTGAGAT GAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGTGATTTTGTCACTGAATTTTTTAAAATTTG CCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAACTGCTGATATAACTCATGCTTTGTC AAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACACACTGCAAAGAAGAAAATCCGAAAACACAG AGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGATGCTGTTTCTGAGAAACCATTAGA TGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTACAATCAGTTCAAGTCTGCACCATCTGACAG TTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGTGGCACACCTCTGGCAGGAATTTGT TCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCCCCAGATCTGAGGTGTTGTTTACTGCATCA GAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAGTGCTTCAGATGTCACTAATATATA TCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGATAAGGAAAAGGGAGAGGTAGGAAAATCTTG GGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGGAAATGGACAAGAGAGTGGCAAGAA AGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAACTTACACTGCTGCATAATGGAGAACCTCT CTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCTGAAGTTTTAGCTAAATTAGGTACATCGGC AGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCTTTTAAGGCAGCTAATCCAGGTTGCTCCCT GGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAAAAGGGCAATGTGGTGCTGAAAGGAGAACT GAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCAATTCCTGCTAGAAGGCAAAGGAGACTCTT TGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGACCTTGCTCGGCACCTGTTACCTTGTGTGAT TCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAGAAGATCATAAAGCAGATAATATCCCATTC CAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAGATTACTAATGTGGAAGCTCTCATTGCCAG AGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAAGATCTTGAAAGGTTTGTGAGTTGCCTGCT GGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCACAAGCTGTTTGTGAATGCCCAGAGGGCTGC AGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCAGAGGAAAGAAGGCAGAACTCCGTGTCAGACTTCCCACCCCCTGC TGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTGCCTCAGCGGATGTACAGTGTTCTCACCAA AGAGGACTTTAGACTTGCAGGTGCCTTTTCATCAGATACTTCCTTCTTCTGATTCTTCTAGCATTACTCGTTGGTGGCTTCAGAGACAGT GCTGCCTCCTCCTGAGGGAGGGAAGGTACCAGGGAGAACCTGGGAGGTCCTGGAGAGGGCCCTGTCCAGTTGGGTGATCAGGAATCAAAC CAGCATCGGAAAGACTTCCCAGCACCAAGCTTGAGCTGTGTCGTTTCGTGGAGGGGGCAGCGAGGATGGGCTTGAGCTGTTGAGAGATTT CTGCCCTAGAGATGGCCTTTGTATATGGGGGGGTGGTGGGGGGACACAAACACATCAGACACTCCGTCCTCACACTGGCAGGACGGTGTT CATCGCATTCTCTTCTGTGACCAGCCTCTAGGCTAGCGGCTGCATTCGTGGTCTGTGCAAACACTTCGTGGTTCTATATATCAGCAGCAA GTGTGCAAAATAAAGGACCTGTTAACTCAGATTTCTGGATATTTTGGTGGTAGCTTCTAGTCCCAGAATCTGTGTTTTTAAAATACTACA TGACATTCTGTCTATTCAATCACCTGGTGGTCATCTTTCTTGTACTAATTAACTGTTGATGAGCATTTTGGATATTCTAGGAGAAAGCCT ATAATTTCACATAGTTTCTCTTTTTCATGTAACTGTAACCTAAATGTATTACTTCTGATAAAACTATATATCAAATGTCACTGCAAATTA GTTTTATATCTGTCATGTGAGATTTGTCTTACTTATTTTTCTTTTGGTTGCCATGGAAGTTATGGCCCTGAAAATCGTCTCCCTCCCCTT CTCTTGCTGTACAGCATGCGTTCTCTTTTTGTGGTTGCTGGCTGGGTACTGTATTTAATGAAGTAGAGAATAGCACTTGCAAAAATACAG TCTTGGTACCTAGAGACTGTCATGCAGATAGTATAATTTGGTATATGTGCTAATGCATTGAGTAGAGGATTATTTTAACACACTATTTTG CTTTTGTATTTTAGTTAAAATAATCGATGGGGATGTGTAGCCCCCCCGTGTGAGGATGACATCACCACATTTCTAGTTTCATGGAGCTCA AGATGTCTTGTGTCTGTGTGGCTAGATGGCCTCTGCTTGGTAATCTTATTTTTAGGCCTAAAATTCCCACTTAAATCCAAAGTAAAAATG GTTATACTGAAGCATAAACCTTGCCTGTGTAATTTTAAAAAATTAATAGAGCTGTGCAAACCCTGTTATTTTTGTAAAAAAAAAAAAAAA TACATATCTATATATAATATGTGTGTGTGTGTGACATATGCACACGTCTCTGTGTATGTGAAGTAGGGGAGGCCCTGGGGGATGACCTCC CAGCCTTTATGATGCTTTTCTCTATGCTGCTGGACTTCATTCTTACTGGTCCACGCAGATGCAGGCGGCCTGAGGCCAGTGCTGTACCAA GTAGAAGACGGTTCCTAAGGACAGAGTTTGTCTGTTTTCTAACAAAGAAAAATTCTACAAAGGAGAGGTTGGGCGTTACAAAGGCATTGT GAATCTAATAAAAGGAAAGTGTCGCTTTCTGTGGCGTTTTCTTTCATTTTCTCCCGCTGAGGCATTTCAGTCTAATTTCATGTGGTTTTG TGCTGTCTCAGCTCTAATGTTTGCAGCCTGCTGAGCCTAACAAGGCAGTGGTCTCAAGAACATTCTTTGTGCCTTTTTAAAGTACTCCAT TTTATTTTTATGATAGTTATGTATTTATTTCACAGATATATTTAAGTACCCACTTTGTGTCAGGTACAGTACAAGCAATGAAGATAAAAC AGAAACCAAAACACACTCCCTTACAGGGAAAACTGACACCACGTTGCCACAAAATGTTGAGTATAGTCAACTCTGCTGTGTGGATCGGAG >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000539493_chr2_135887565_+_3603nt GGAAAAAAGCGACTTGTGGCGGTCGAGCGTGGCGCAGGCGAATCCTCGGCACTAAGCAAATATGGACCTCGCGGCGGCAGCGGAGCCGGG CGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTCCTGGACTTCTTGGAGGAGTTTCAGAGCAG CGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACATTGGTTGTGAGTTTTGTGGACCTGGAACA ATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTGTGTCGGGCCTTGAAAACATTCGTCAAAGA CCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGACACAAGATTCGAGAGCTCACCTCATCCAG AATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAGCTTGTGAGCGGAACTTTTCTGTGCTTGGA CTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGCCGAAATCCAGTTTGTGCCAACAGGAGGAG ATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAGACCCAAGCTGAGCTTCCTCGAGGGAGTAT CCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGACAAGTGTGACTTTACAGGGACACTGATTGT TGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTCAGTGGTGTTGATGGATATGAGACAGAAGG CATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCCTGCTGTGTTGCGCCAACCAACCCAAGGTT TGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACTGTGAAAGAATGGGAGAAAGTGTTTGAGAT GAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGTGATTTTGTCACTGAATTTTTTAAAATTTG CCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAACTGCTGATATAACTCATGCTTTGTC AAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACACACTGCAAAGAAGAAAATCCGAAAACACAG AGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGATGCTGTTTCTGAGAAACCATTAGA TGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTACAATCAGTTCAAGTCTGCACCATCTGACAG TTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGTGGCACACCTCTGGCAGGAATTTGT TCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCCCCAGATCTGAGGTGTTGTTTACTGCATCA GAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAGTGCTTCAGATGTCACTAATATATA TCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGATAAGGAAAAGGGAGAGGTAGGAAAATCTTG GGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGGAAATGGACAAGAGAGTGGCAAGAA AGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAACTTACACTGCTGCATAATGGAGAACCTCT CTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCTGAAGTTTTAGCTAAATTAGGTACATCGGC AGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCTTTTAAGGCAGCTAATCCAGGTTGCTCCCT GGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAAAAGGGCAATGTGGTGCTGAAAGGAGAACT GAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCAATTCCTGCTAGAAGGCAAAGGAGACTCTT TGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGACCTTGCTCGGCACCTGTTACCTTGTGTGAT TCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAGAAGATCATAAAGCAGATAATATCCCATTC CAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAGATTACTAATGTGGAAGCTCTCATTGCCAG AGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAAGATCTTGAAAGGTTTGTGAGTTGCCTGCT GGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCACAAGCTGTTTGTGAATGCCCAGAGGGCTGC AGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCAGAGGAAAGAAGGCAGAACTCCGTGTCAGACTTCCCACCCCCTGC TGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTGCCTCAGCGGATGTACAGTGTTCTCACCAA AGAGGACTTTAGACTTGCAGTTAAAATAATCGATGGGGATGTGTAGCCCCCCCGTGTGAGGATGACATCACCACATTTCTAGTTTCATGG AGCTCAAGATGTCTTGTGTCTGTGTGGCTAGATGGCCTCTGCTTGCTCCCCAGGTGTGTCCTGGTAGACAACTGCTCCCAGGAGCTGGCA TAGAAGCAAACCTGCAGGAAAAGCCAACCCACTCCAGGTGTGTGGAAGCTGCTGGCAGGAACCCAGCAAGGATCCAGCTGGGTTGTAATG GAAACAATGCAACCAACAATCCTTGAGCGAGCCGGGATAGATGTGGCCTCATCACTGAAGATTTCATCTGAGACCTCTGCAAATATCCAA ATTGTATATGCTCTTAGAGCAGATCATTTTCTCACAGGTTGTCTAACCAAAGGAAAGGAAATCAGCATATCAAAGAGATATCTGCACTCC CATGTTGATTGCAGCACTGTTCACAACAGCCAAGATGTGGAATCAACCAGAGTGTCCATTGGCAGATGAATGGATTAAAAATGTGGTGCA >In-frame_MCM6_ENST00000264156_chr2_136622583_-_RAB3GAP1_ENST00000442034_chr2_135887565_+_4341nt GGAAAAAAGCGACTTGTGGCGGTCGAGCGTGGCGCAGGCGAATCCTCGGCACTAAGCAAATATGGACCTCGCGGCGGCAGCGGAGCCGGG CGCCGGCAGCCAGCACCTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTCCTGGACTTCTTGGAGGAGTTTCAGAGCAG CGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACATTGGTTGTGAGTTTTGTGGACCTGGAACA ATTTAACCAGCAACTTTCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTGTGTCGGGCCTTGAAAACATTCGTCAAAGA CCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGACACAAGATTCGAGAGCTCACCTCATCCAG AATTGGTTTGCTCACTCGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAGCTTGTGAGCGGAACTTTTCTGTGCTTGGA CTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGCCGAAATCCAGTTTGTGCCAACAGGAGGAG ATTCTTACTGGATACAAATAAATCAAGATTTGTTGATTTTCAAAAGGTTCGTATTCAAGAGACCCAAGCTGAGCTTCCTCGAGGGAGTAT CCCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGACAAGTGTGACTTTACAGGGACACTGATTGT TGTGCCTGACGTCTCCAAGCTTAGCACACCAGGAGCACGTGCAGAAACTAATTCCCGTGTCAGTGGTGTTGATGGATATGAGACAGAAGG CATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCCTGCTGTGTTGCGCCAACCAACCCAAGGTT TGGGGGGAAAGAGCTCAGAGATGAGGAACAGACAGCTGAGAGCATTAAGAACCAAATGACTGTGAAAGAATGGGAGAAAGTGTTTGAGAT GAGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGTGATTTTGTCACTGAATTTTTTAAAATTTG CCGTCGAAAGGAGTCAACTGATGAGATTCTTGGACGATCTGCATTTGAGGAAGAAGGCAAAGAAACTGCTGATATAACTCATGCTTTGTC AAAATTGACAGAGCCGGCATCAGTTCCAATTCATAAATTATCAGTTTCAAATATGGTACACACTGCAAAGAAGAAAATCCGAAAACACAG AGGTGTAGAGGAGTCACCGCTAAATAATGATGTTCTTAATACTATTCTCCTGTTCTTATTCCCTGATGCTGTTTCTGAGAAACCATTAGA TGGAACTACTTCAACAGATAATAATAATCCTCCATCAGAGAGTGAAGACTATAATCTCTACAATCAGTTCAAGTCTGCACCATCTGACAG TTTAACATACAAACTGGCTTTGTGTCTCTGTATGATCAATTTTTACCATGGAGGGTTGAAAGGAGTGGCACACCTCTGGCAGGAATTTGT TCTTGAAATGCGTTTCCGATGGGAAAACAACTTTCTGATTCCAGGATTAGCAAGTGGACCCCCAGATCTGAGGTGTTGTTTACTGCATCA GAAACTACAGATGTTAAATTGTTGTATTGAAAGAAAGAAGGCACGTGATGAGGGGAAAAAGACAAGTGCTTCAGATGTCACTAATATATA TCCAGGGGATGCTGGAAAAGCAGGAGACCAGTTGGTGCCAGATAATCTAAAAGAAACAGATAAGGAAAAGGGAGAGGTAGGAAAATCTTG GGATTCCTGGAGTGACAGCGAAGAAGAATTTTTTGAATGCCTAAGTGATACTGAAGAACTTAAAGGAAATGGACAAGAGAGTGGCAAGAA AGGAGGACCTAAGGAGATGGCAAATTTAAGGCCGGAAGGACGGCTCTATCAGCATGGGAAACTTACACTGCTGCATAATGGAGAACCTCT CTACATTCCAGTAACCCAGGAACCAGCACCTATGACAGAAGATCTGCTAGAAGAGCAGTCTGAAGTTTTAGCTAAATTAGGTACATCGGC AGAGGGGGCTCACCTTCGAGCACGCATGCAGAGTGCCTGTCTGCTCTCAGATATGGAGTCTTTTAAGGCAGCTAATCCAGGTTGCTCCCT GGAAGATTTTGTGAGGTGGTATTCACCCCGGGATTATATTGAAGAGGAGGTGATTGATGAAAAGGGCAATGTGGTGCTGAAAGGAGAACT GAGTGCCCGGATGAAGATTCCAAGCAATATGTGGGTAGAAGCCTGGGAAACAGCTAAGCCAATTCCTGCTAGAAGGCAAAGGAGACTCTT TGATGATACACGGGAAGCAGAAAAGGTGCTGCACTATCTGGCAATCCAGAAACCTGCAGACCTTGCTCGGCACCTGTTACCTTGTGTGAT TCATGCAGCTGTACTCAAGGTAAAGGAAGAAGAAAGTCTCGAAAACATTTCTTCAGTTAAGAAGATCATAAAGCAGATAATATCCCATTC CAGTAAAGTTTTGCACTTCCCCAATCCAGAAGACAAGAAATTGGAAGAAATCATTCACCAGATTACTAATGTGGAAGCTCTCATTGCCAG AGCTCGGTCACTAAAAGCCAAGTTTGGAACTGAGAAATGTGAACAGGAGGAGGAAAAGGAAGATCTTGAAAGGTTTGTGAGTTGCCTGCT GGAGCAGCCTGAAGTGTTAGTCACCGGTGCAGGAAGAGGACATGCTGGCAGGATCATTCACAAGCTGTTTGTGAATGCCCAGAGGCTGAC TGAATCTTCTGATGAGGCTGCAGCTATGACTCCACCAGAGGAGGAATTGAAGAGAATGGGCTCCCCAGAGGAAAGAAGGCAGAACTCCGT GTCAGACTTCCCACCCCCTGCTGGCCGGGAATTCATTTTGCGCACCACTGTGCCGCGCCCTGCTCCCTACTCCAAAGCTCTGCCTCAGCG GATGTACAGTGTTCTCACCAAAGAGGACTTTAGACTTGCAGGTGCCTTTTCATCAGATACTTCCTTCTTCTGATTCTTCTAGCATTACTC GTTGGTGGCTTCAGAGACAGTGCTGCCTCCTCCTGAGGGAGGGAAGGTACCAGGGAGAACCTGGGAGGTCCTGGAGAGGGCCCTGTCCAG TTGGGTGATCAGGAATCAAACCAGCATCGGAAAGACTTCCCAGCACCAAGCTTGAGCTGTGTCGTTTCGTGGAGGGGGCAGCGAGGATGG GCTTGAGCTGTTGAGAGATTTCTGCCCTAGAGATGGCCTTTGTATATGGGGGGGTGGTGGGGGGACACAAACACATCAGACACTCCGTCC TCACACTGGCAGGACGGTGTTCATCGCATTCTCTTCTGTGACCAGCCTCTAGGCTAGCGGCTGCATTCGTGGTCTGTGCAAACACTTCGT GGTTCTATATATCAGCAGCAAGTGTGCAAAATAAAGGACCTGTTAACTCAGATTTCTGGATATTTTGGTGGTAGCTTCTAGTCCCAGAAT CTGTGTTTTTAAAATACTACATGACATTCTGTCTATTCAATCACCTGGTGGTCATCTTTCTTGTACTAATTAACTGTTGATGAGCATTTT GGATATTCTAGGAGAAAGCCTATAATTTCACATAGTTTCTCTTTTTCATGTAACTGTAACCTAAATGTATTACTTCTGATAAAACTATAT ATCAAATGTCACTGCAAATTAGTTTTATATCTGTCATGTGAGATTTGTCTTACTTATTTTTCTTTTGGTTGCCATGGAAGTTATGGCCCT GAAAATCGTCTCCCTCCCCTTCTCTTGCTGTACAGCATGCGTTCTCTTTTTGTGGTTGCTGGCTGGGTACTGTATTTAATGAAGTAGAGA ATAGCACTTGCAAAAATACAGTCTTGGTACCTAGAGACTGTCATGCAGATAGTATAATTTGGTATATGTGCTAATGCATTGAGTAGAGGA TTATTTTAACACACTATTTTGCTTTTGTATTTTAGTTAAAATAATCGATGGGGATGTGTAGCCCCCCCGTGTGAGGATGACATCACCACA TTTCTAGTTTCATGGAGCTCAAGATGTCTTGTGTCTGTGTGGCTAGATGGCCTCTGCTTGGTAATCTTATTTTTAGGCCTAAAATTCCCA CTTAAATCCAAAGTAAAAATGGTTATACTGAAGCATAAACCTTGCCTGTGTAATTTTAAAAAATTAATAGAGCTGTGCAAACCCTGTTAT |
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FusionGenePPI for MCM6_RAB3GAP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MCM6 | MCM6, IL36RN, ALS2CR11, PSMA1, SCNM1, ING5, MLLT3, MCM2, MCM10, MCM8, MCM4, MCM7, ORC1, ORC2, ORC4, CDC45, RPA1, MCM5, CDT1, TNFAIP3, USP49, USP7, TAF10, PMS1, AIRE, HIST1H4A, SSRP1, SRRM2, EMD, ASF1B, L3MBTL1, HDAC5, MMS22L, TONSL, CDKN2A, PSMA3, CCND1, SIRT7, ASF1A, CUL3, CDK2, MCM3, SF3A1, SF3B1, DCTN2, BARD1, ECT2, PAXIP1, TP53BP1, CDC7, DBF4, FN1, VCAM1, ORC6, CCNA1, GMNN, ITGA4, SMC1A, BAG3, MCMBP, HSP90AB1, ACLY, CAP1, KPNA3, POLK, HUWE1, NUDT2, SNRPB2, FAM161A, ZBTB9, OBSL1, CCDC8, ILF2, SPIN2B, HIST1H2BA, HSPB1, MAPRE2, NTRK1, HIST1H3E, TRPS1, FOXQ1, USP37, EGFR, HIST1H3A, H2AFX, SPAG9, USP15, EPS15L1, IVNS1ABP, GTF3C4, SMC3, GAPVD1, ANK3, SBNO1, CDK11A, SOX4, BCR, PPP4R2, HSF1, KIAA1468, PLK1, ATG2B, DLD, SDHA, SOD1, FANCD2, BRCA1 | RAB3GAP1 | RPH3AL, WDR7, DMXL2, MAP1LC3A, FEZ1, FEZ2, RAB22A, RAB39A, RAB39B, LMAN1, PAXIP1, VCP, GABPA, GNE, NCOA7, RAB3GAP2, TSEN34, VAPB, VAPA, BCAT1, BTN2A1, SIRT2, DCAF15, NTRK1, NPHP1, BRAF, ALOX5, C6orf141, DOCK5, RCCD1, PSMC4, TRIM25, TES |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MCM6_RAB3GAP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MCM6_RAB3GAP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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