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Fusion gene ID: 21250 |
FusionGeneSummary for MBTPS2_EDEM2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MBTPS2_EDEM2 | Fusion gene ID: 21250 | Hgene | Tgene | Gene symbol | MBTPS2 | EDEM2 | Gene ID | 51360 | 55741 |
| Gene name | membrane bound transcription factor peptidase, site 2 | ER degradation enhancing alpha-mannosidase like protein 2 | |
| Synonyms | BRESEK|IFAP|KFSD|KFSDX|OLMSX|S2P | C20orf31|C20orf49|bA4204.1 | |
| Cytomap | Xp22.12 | 20q11.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | membrane-bound transcription factor site-2 proteaseSREBPs intramembrane proteaseendopeptidase S2Pkeratosis follicularis spinulosa decalvansmembrane-bound transcription factor protease, site 2site-2 proteasesterol regulatory element-binding proteins | ER degradation-enhancing alpha-mannosidase-like protein 2ER degradation enhancer, mannosidase alpha-like 2ER degradation-enhancing alpha-mannosidase-like 2ER degradation-enhancing-mannosidase-like protein 2 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | O43462 | Q9BV94 | |
| Ensembl transtripts involved in fusion gene | ENST00000379484, ENST00000365779, ENST00000465888, | ENST00000540582, ENST00000374491, ENST00000374492, ENST00000541621, ENST00000542871, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 7 X 7 X 5=245 |
| # samples | 1 | 7 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MBTPS2 [Title/Abstract] AND EDEM2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AN-A0AM-01A | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000379484 | ENST00000540582 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| In-frame | ENST00000379484 | ENST00000374491 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| In-frame | ENST00000379484 | ENST00000374492 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| In-frame | ENST00000379484 | ENST00000541621 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| In-frame | ENST00000379484 | ENST00000542871 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000365779 | ENST00000540582 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000365779 | ENST00000374491 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000365779 | ENST00000374492 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000365779 | ENST00000541621 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000365779 | ENST00000542871 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000465888 | ENST00000540582 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000465888 | ENST00000374491 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000465888 | ENST00000374492 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000465888 | ENST00000541621 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
| intron-3CDS | ENST00000465888 | ENST00000542871 | MBTPS2 | chrX | 21896810 | + | EDEM2 | chr20 | 33714178 | - |
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FusionProtFeatures for MBTPS2_EDEM2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MBTPS2 | EDEM2 |
| Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segmentthereby releasing the N-terminal segment with a portion of thetransmembrane segment attached. Site-2 cleavage comes after site-1cleavage which takes place in the lumenal loop. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 109_136 | 420 | 520 | Compositional bias | Note=Poly-Ser |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 285_386 | 420 | 520 | Compositional bias | Note=Cys-rich |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 380_384 | 420 | 520 | Compositional bias | Note=Poly-Ser |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 108_144 | 420 | 520 | Topological domain | Lumenal |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 1_3 | 420 | 520 | Topological domain | Cytoplasmic |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 25_74 | 420 | 520 | Topological domain | Lumenal |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 145_169 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 174_186 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 187_209 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 229_251 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 4_24 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 75_95 | 420 | 520 | Transmembrane | Helical |
| Hgene | MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 96_107 | 420 | 520 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 252_446 | 420 | 520 | Topological domain | Lumenal |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 477_492 | 420 | 520 | Topological domain | Lumenal |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 514_519 | 420 | 520 | Topological domain | Cytoplasmic |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 447_464 | 420 | 520 | Transmembrane | Helical |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 465_476 | 420 | 520 | Transmembrane | Helical |
| Hgene | >MBTPS2 | chrX:21896810 | chr20:33714178 | ENST00000379484 | + | 9 | 11 | 493_513 | 420 | 520 | Transmembrane | Helical |
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FusionGeneSequence for MBTPS2_EDEM2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000540582_chr20_33714178_-_585aa MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSS FFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAI REQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGP RGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLP ARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTEYNKAIRNYTRFDDWYLWVQMYKGTVSMPV FQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374491_chr20_33714178_-_718aa MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSS FFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAI REQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGP RGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLP ARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTEYNKAIRNYTRFDDWYLWVQMYKGTVSMPV FQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRL >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374492_chr20_33714178_-_718aa MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSS FFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAI REQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGP RGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLP ARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTEYNKAIRNYTRFDDWYLWVQMYKGTVSMPV FQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRL >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000541621_chr20_33714178_-_718aa MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSS FFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAI REQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGP RGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLP ARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTEYNKAIRNYTRFDDWYLWVQMYKGTVSMPV FQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRL >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000542871_chr20_33714178_-_718aa MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSS FFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAI REQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGP RGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLP ARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTEYNKAIRNYTRFDDWYLWVQMYKGTVSMPV FQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIE KISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000540582_chr20_33714178_-_1755nt ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTT AAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCA TTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTTCCTGGTATA AATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACTCATTTGCAA CTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCCATTGGACCC AGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATAATACCTTCT TTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA GAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCCATGCCAGTC TTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAACTACTACACT GTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCACTTCGGCCA GAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAATCCATTGAA AAAATCAGCAAGGTGGAGTGCGGATTTGCAACAGTAAGTGTTTGCATGGCCCCAAGAACTGGGAAGAGTCTCCCCTTGCTGCTAAAAAGC >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374491_chr20_33714178_-_2154nt ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTT AAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCA TTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTTCCTGGTATA AATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACTCATTTGCAA CTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCCATTGGACCC AGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATAATACCTTCT TTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA GAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCCATGCCAGTC TTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAACTACTACACT GTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCACTTCGGCCA GAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAATCCATTGAA AAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTCTTCCTGGCC GAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATCACCCCCTAT GGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGCCAGAGGCTG AAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAACACTGTTAGT TCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCTGCCAAACAG >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374492_chr20_33714178_-_2154nt ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTT AAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCA TTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTTCCTGGTATA AATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACTCATTTGCAA CTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCCATTGGACCC AGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATAATACCTTCT TTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA GAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCCATGCCAGTC TTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAACTACTACACT GTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCACTTCGGCCA GAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAATCCATTGAA AAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTCTTCCTGGCC GAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATCACCCCCTAT GGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGCCAGAGGCTG AAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAACACTGTTAGT TCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCTGCCAAACAG >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000541621_chr20_33714178_-_2154nt ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTT AAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCA TTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTTCCTGGTATA AATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACTCATTTGCAA CTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCCATTGGACCC AGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATAATACCTTCT TTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA GAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCCATGCCAGTC TTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAACTACTACACT GTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCACTTCGGCCA GAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAATCCATTGAA AAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTCTTCCTGGCC GAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATCACCCCCTAT GGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGCCAGAGGCTG AAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAACACTGTTAGT TCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCTGCCAAACAG >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000542871_chr20_33714178_-_2154nt ATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCTGTCTATTTT AAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTCAATCGTGCC TTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATGTTTAGCTCA TTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCTTCTTCCTCT TCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTTCCTGGTATA AATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATAGCAGCTATT AGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACTCATTTGCAA CTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTAGCTCTTGTT CTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCCATTGGACCC AGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTAGATACCATC GCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGACTAGATGGT TCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACATGTCTTCCT GCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATAATACCTTCT TTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTTCACTACACA GAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCCATGCCAGTC TTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAACTACTACACT GTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCACTTCGGCCA GAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAATCCATTGAA AAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTCTTCCTGGCC GAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATCACCCCCTAT GGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGCCAGAGGCTG AAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAACACTGTTAGT TCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCTGCCAAACAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000540582_chr20_33714178_-_2325nt AGCGGATGCTGGGGCTGTAAGGCGCGCGCGGTCAGCTGTTGGCGGTGCAGGGAGGAGGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCT GTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATG TTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTT CCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATA GCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACT CATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTA GCTCTTGTTCTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCC ATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTA GATACCATCGCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGA CTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACA TGTCTTCCTGCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATA ATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTT CACTACACAGAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCC ATGCCAGTCTTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAAC TACTACACTGTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCA CTTCGGCCAGAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAA TCCATTGAAAAAATCAGCAAGGTGGAGTGCGGATTTGCAACAGTAAGTGTTTGCATGGCCCCAAGAACTGGGAAGAGTCTCCCCTTGCTG CTAAAAAGCCTCTTTAAGGGTAGAGCTTTGGGAGTTCTGACATATCAGCACTAGAAGGGACCTTGGAGATATACATAATGCTCATATTTT ACAGATGGGGAGACCAAAGAACAGAGAAGCTAAGTGCCTTGCTAAAGATCTCACAGCTAGTAGAGGTAGAGCTAGAATTAGTTCCTTGGG ATCTTGACCCCGGCCCTTGGCATTCCTCCCACAGTGGAGATCTTTGATCTGTTTGAATAGGTGACTTTGAAAAGGTGAGTTTAGCGAAAA GTTTTGTGAGACACTAAAATAGATTTTAAGGGGAATCCAGAGTCCCATAGCCCTATATTCAAACCTGGGACTCCTTAACAAAGCAGTCCT GCTTAGTCTCACAGATATTTCTTGAATGTCTTTCACATGCCAGGCACTCTGCTAGGCCCAAGGGTTACAGCAGTGGCCTTGCTCTCATGG >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374491_chr20_33714178_-_2322nt AGCGGATGCTGGGGCTGTAAGGCGCGCGCGGTCAGCTGTTGGCGGTGCAGGGAGGAGGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCT GTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATG TTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTT CCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATA GCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACT CATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTA GCTCTTGTTCTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCC ATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTA GATACCATCGCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGA CTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACA TGTCTTCCTGCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATA ATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTT CACTACACAGAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCC ATGCCAGTCTTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAAC TACTACACTGTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCA CTTCGGCCAGAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAA TCCATTGAAAAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTC TTCCTGGCCGAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATC ACCCCCTATGGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGC CAGAGGCTGAAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAAC ACTGTTAGTTCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCT GCCAAACAGAAGGTCCCACTTCTCAGCTGCCCCAGTCAGCCCTTCACCTCCAAGTTGGCATTACTGGGACAGGTTTTCCTAGACTCCTCA >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000374492_chr20_33714178_-_2322nt AGCGGATGCTGGGGCTGTAAGGCGCGCGCGGTCAGCTGTTGGCGGTGCAGGGAGGAGGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCT GTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATG TTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTT CCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATA GCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACT CATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTA GCTCTTGTTCTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCC ATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTA GATACCATCGCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGA CTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACA TGTCTTCCTGCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATA ATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTT CACTACACAGAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCC ATGCCAGTCTTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAAC TACTACACTGTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCA CTTCGGCCAGAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAA TCCATTGAAAAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTC TTCCTGGCCGAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATC ACCCCCTATGGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGC CAGAGGCTGAAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAAC ACTGTTAGTTCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCT GCCAAACAGAAGGTCCCACTTCTCAGCTGCCCCAGTCAGCCCTTCACCTCCAAGTTGGCATTACTGGGACAGGTTTTCCTAGACTCCTCA >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000541621_chr20_33714178_-_2321nt AGCGGATGCTGGGGCTGTAAGGCGCGCGCGGTCAGCTGTTGGCGGTGCAGGGAGGAGGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCT GTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATG TTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTT CCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATA GCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACT CATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTA GCTCTTGTTCTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCC ATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTA GATACCATCGCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGA CTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACA TGTCTTCCTGCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATA ATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTT CACTACACAGAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCC ATGCCAGTCTTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAAC TACTACACTGTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCA CTTCGGCCAGAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAA TCCATTGAAAAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTC TTCCTGGCCGAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATC ACCCCCTATGGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGC CAGAGGCTGAAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAAC ACTGTTAGTTCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCT GCCAAACAGAAGGTCCCACTTCTCAGCTGCCCCAGTCAGCCCTTCACCTCCAAGTTGGCATTACTGGGACAGGTTTTCCTAGACTCCTCA >In-frame_MBTPS2_ENST00000379484_chrX_21896810_+_EDEM2_ENST00000542871_chr20_33714178_-_2319nt AGCGGATGCTGGGGCTGTAAGGCGCGCGCGGTCAGCTGTTGGCGGTGCAGGGAGGAGGACGCCGGGGCTCGCCTTCCCTCCTCTGCCGCC GCTGCCGCCATGATTCCGGTGTCGCTGGTGGTGGTGGTGGTGGGTGGCTGGACTGTCGTCTACCTGACCGACTTGGTGCTGAAGTCATCT GTCTATTTTAAACATTCTTATGAAGACTGGCTGGAAAACAACGGACTGAGCATCTCCCCTTTCCACATAAGATGGCAAACTGCTGTTTTC AATCGTGCCTTTTACAGTTGGGGACGGCGGAAAGCAAGGATGCTTTACCAATGGTTCAATTTTGGAATGGTGTTTGGCGTAATTGCCATG TTTAGCTCATTTTTTCTCCTTGGAAAAACGCTGATGCAGACTTTGGCACAAATGATGGCTGACTCTCCCTCTTCTTATTCTTCCTCCTCT TCTTCCTCTTCCTCCTCTTCTTCCTCTTCCTCTTCTTCATCTTCTTCCTCTTCCTCGCTTCACAATGAACAGGTGTTACAAGTTGTGGTT CCTGGTATAAATTTACCCGTCAATCAACTGACCTATTTCTTCACGGCAGTTCTCATTAGTGGTGTTGTACATGAAATTGGACATGGGATA GCAGCTATTAGGGAACAAGTTCGATTTAATGGCTTTGGGATTTTTCTCTTCATTATTTATCCTGGAGCATTTGTTGATCTGTTCACCACT CATTTGCAACTTATATCGCCAGTCCAGCAGCTAAGGATATTTTGTGCAGGTATCTGGCATAATTTTGTCCTTGCACTCTTGGGTATTTTA GCTCTTGTTCTCCTCCCAGTAATTCTCTTGCCATTTTACTACACTGGAGTTGGGGTGCTCATCACTGAAGTTGCTGAGGACTCTCCTGCC ATTGGACCCAGAGGCCTTTTTGTGGGAGACCTTGTCACCCATCTACAGGATTGTCCTGTTACTAATGTGCAAGATTGGAATGAATGTTTA GATACCATCGCCTATGAGCCCCAAATTGGTTACTGTATAAGTGCATCAACTTTACAGCAGTTAAGTTTCCCAGTTAGAGCATACAAACGA CTAGATGGTTCAACTGAATGCTGTAACAATCACAGCCTCACAGATGTGTGCTTTTCCTACAGAAATAATTTTAATAAGCGTTTGCATACA TGTCTTCCTGCCCGGAAAGCAGTTGAAGCAACTCAAGTTTGCAGAACCAATAAAGACTGTAAAAAAAGCTCAAGTTCAAGTTTCTGTATA ATACCTTCTTTGGAAACTCACACTCGCTTAATAAAAGTAAAACACCCACCTCAGATTGATATGTTATACGTAGGACATCCTCTGCATCTT CACTACACAGAGTATAACAAAGCCATCCGGAACTACACCCGCTTCGATGACTGGTACCTGTGGGTTCAGATGTACAAGGGGACTGTGTCC ATGCCAGTCTTCCAGTCCTTGGAGGCCTACTGGCCTGGTCTTCAGAGCCTCATTGGAGACATTGACAATGCCATGAGGACCTTCCTCAAC TACTACACTGTATGGAAGCAGTTTGGGGGGCTCCCGGAATTCTACAACATTCCTCAGGGATACACAGTGGAGAAGCGAGAGGGCTACCCA CTTCGGCCAGAACTTATTGAAAGCGCAATGTACCTCTACCGTGCCACGGGGGATCCCACCCTCCTAGAACTCGGAAGAGATGCTGTGGAA TCCATTGAAAAAATCAGCAAGGTGGAGTGCGGATTTGCAACAATCAAAGATCTGCGAGACCACAAGCTGGACAACCGCATGGAGTCGTTC TTCCTGGCCGAGACTGTGAAATACCTCTACCTCCTGTTTGACCCAACCAACTTCATCCACAACAATGGGTCCACCTTCGACGCGGTGATC ACCCCCTATGGGGAGTGCATCCTGGGGGCTGGGGGGTACATCTTCAACACAGAAGCTCACCCCATCGACCCTGCCGCCCTGCACTGCTGC CAGAGGCTGAAGGAAGAGCAGTGGGAGGTGGAGGACTTGATGAGGGAATTCTACTCTCTCAAACGGAGCAGGTCGAAATTTCAGAAAAAC ACTGTTAGTTCGGGGCCATGGGAACCTCCAGCAAGGCCAGGAACACTCTTCTCACCAGAAAACCATGACCAGGCAAGGGAGAGGAAGCCT GCCAAACAGAAGGTCCCACTTCTCAGCTGCCCCAGTCAGCCCTTCACCTCCAAGTTGGCATTACTGGGACAGGTTTTCCTAGACTCCTCA |
Top |
FusionGenePPI for MBTPS2_EDEM2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MBTPS2 | SYVN1, SARAF, FAM8A1, IL17RC | EDEM2 | RPS3A, TAZ, TMEM30A, CYTIP, HLA-E, FBLN7, CHST8, NAAA, HEPACAM2, OLFM1, SEL1L, CANX, SHH, UHMK1, PSMC5, PTPLA, CLU, C3orf33, GPR114, TMPRSS11B, TXNDC11, B3GNT2, SLC35B2, ANGPTL7, THBS2, MCU, SLC16A10, DCT, MXD3, OS9, BRINP3, SURF1, BLK, LYZL1, C19orf52, SLC25A16, SLC38A10, LYPD4, TMTC4, TVP23C, MCL1, BRINP2, SFXN3, C8G, OMA1, EDEM3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MBTPS2_EDEM2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MBTPS2_EDEM2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MBTPS2 | C1839988 | Ichthyosis follicularis atrichia photophobia syndrome | 1 | CTD_human;ORPHANET;UNIPROT |
| Hgene | MBTPS2 | C2239176 | Liver carcinoma | 1 | CTD_human |
| Hgene | MBTPS2 | C3806745 | PALMOPLANTAR KERATODERMA, MUTILATING, WITH PERIORIFICIAL KERATOTIC PLAQUES, X-LINKED | 1 | UNIPROT |
| Hgene | MBTPS2 | C3887525 | Keratosis Follicularis Spinulosa Decalvans, X-Linked | 1 | UNIPROT |
| Tgene | EDEM2 | C0036341 | Schizophrenia | 1 | CTD_human |
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