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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 20892

FusionGeneSummary for MAP4K3_EML4

check button Fusion gene summary
Fusion gene informationFusion gene name: MAP4K3_EML4
Fusion gene ID: 20892
HgeneTgene
Gene symbol

MAP4K3

EML4

Gene ID

8491

27436

Gene namemitogen-activated protein kinase kinase kinase kinase 3echinoderm microtubule associated protein like 4
SynonymsGLK|MAPKKKK3|MEKKK 3|MEKKK3|RAB8IPL1C2orf2|ELP120|EMAP-4|EMAPL4|ROPP120
Cytomap

2p22.1

2p21

Type of geneprotein-codingprotein-coding
Descriptionmitogen-activated protein kinase kinase kinase kinase 3MAPK/ERK kinase kinase kinase 3MEK kinase kinase 3germinal center kinase-like kinasegerminal center kinase-related protein kinaseechinoderm microtubule-associated protein-like 4restrictedly overexpressed proliferation-associated proteinropp 120
Modification date2018052320180523
UniProtAcc

Q8IVH8

Q9HC35

Ensembl transtripts involved in fusion geneENST00000263881, ENST00000437545, 
ENST00000341681, ENST00000484274, 
ENST00000536018, ENST00000474502, 
ENST00000318522, ENST00000402711, 
ENST00000482660, ENST00000401738, 
ENST00000453191, 
Fusion gene scores* DoF score7 X 4 X 6=1687 X 9 X 4=252
# samples 89
** MAII scorelog2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/252*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MAP4K3 [Title/Abstract] AND EML4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMAP4K3

GO:0006468

protein phosphorylation

9275185

HgeneMAP4K3

GO:0009411

response to UV

9275185

HgeneMAP4K3

GO:0034612

response to tumor necrosis factor

9275185

HgeneMAP4K3

GO:0035556

intracellular signal transduction

9275185


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVHNSCTCGA-QK-A8ZB-01AMAP4K3chr2

39605207

-EML4chr2

42507990

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263881ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
In-frameENST00000263881ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000263881ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000263881ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000263881ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+
5UTR-3CDSENST00000437545ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
5UTR-3CDSENST00000437545ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
5UTR-intronENST00000437545ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
5UTR-intronENST00000437545ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
5UTR-intronENST00000437545ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+
In-frameENST00000341681ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
In-frameENST00000341681ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000341681ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000341681ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000341681ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+
In-frameENST00000484274ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
In-frameENST00000484274ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000484274ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000484274ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
5CDS-intronENST00000484274ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-3CDSENST00000536018ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-3CDSENST00000536018ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000536018ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000536018ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000536018ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-3CDSENST00000474502ENST00000318522MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-3CDSENST00000474502ENST00000402711MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000474502ENST00000482660MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000474502ENST00000401738MAP4K3chr2

39605207

-EML4chr2

42507990

+
intron-intronENST00000474502ENST00000453191MAP4K3chr2

39605207

-EML4chr2

42507990

+

Top

FusionProtFeatures for MAP4K3_EML4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAP4K3

Q8IVH8

EML4

Q9HC35

May play a role in the response to environmental stress.Appears to act upstream of the JUN N-terminal pathway.{ECO:0000269|PubMed:9275185}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000263881-23422_3051895Nucleotide bindingATP
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000341681-23322_3051874Nucleotide bindingATP
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523259_297222982RepeatNote=WD 1
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523301_348222982RepeatNote=WD 2
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523356_396222982RepeatNote=WD 3
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523403_438222982RepeatNote=WD 4
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523445_484222982RepeatNote=WD 5
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523500_538222982RepeatNote=WD 6
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523543_579222982RepeatNote=WD 7
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523582_621222982RepeatNote=WD 8
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523625_662222982RepeatNote=WD 9
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523668_704222982RepeatNote=WD 10
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523711_750222982RepeatNote=WD 11
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523760_818222982RepeatNote=WD 12
TgeneEML4chr2:39605207chr2:42507990ENST00000318522+523825_864222982RepeatNote=WD 13
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422259_297164924RepeatNote=WD 1
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422301_348164924RepeatNote=WD 2
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422356_396164924RepeatNote=WD 3
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422403_438164924RepeatNote=WD 4
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422445_484164924RepeatNote=WD 5
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422500_538164924RepeatNote=WD 6
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422543_579164924RepeatNote=WD 7
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422582_621164924RepeatNote=WD 8
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422625_662164924RepeatNote=WD 9
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422668_704164924RepeatNote=WD 10
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422711_750164924RepeatNote=WD 11
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422760_818164924RepeatNote=WD 12
TgeneEML4chr2:39605207chr2:42507990ENST00000402711+422825_864164924RepeatNote=WD 13

- In-frame and not-retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000263881-23416_27351895DomainProtein kinase
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000263881-234556_86751895DomainCNH
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000341681-23316_27351874DomainProtein kinase
HgeneMAP4K3chr2:39605207chr2:42507990ENST00000341681-233556_86751874DomainCNH


Top

FusionGeneSequence for MAP4K3_EML4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS

>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_811aa
MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKL
EWAYGYRGKDCRANVYLLPTGKIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTL
STLQIIGLGTFERGVGCLDFSKADSGVHLCIIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGN
SLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDR
KIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNS
MEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKY
SRYGRCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNR
KVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKDMSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTES
VIQSNTPTPPPSQPLNETAEEESRISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLEDQQDPSPSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC

>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_2433nt
ATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTC
TACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATG
CGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTG
GAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTA
GTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAA
ATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTA
TCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGT
ATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTT
GTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAAT
TCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTT
ACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATC
AGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGA
AAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGA
AAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCAT
ACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCA
ATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGA
ACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATG
CGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATAT
AGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGA
GACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATAT
ACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGA
AAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGT
GCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAG
TGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGT
GTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACA
CTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAG
CCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_5099nt
AAGGGGAGGGGGAGGAGCGGCGAAAGCGGAAGCCATGTTGGAGTTTCACCCCGAGCGAGGGGCTGCGAGGGTTCTCCTCTCCTTGTGGGT
GTGACCAGGTTCGGCGCGGCGGCGGGCCGCGGGGGGCGGGGACGATTGGCCGCTTGTCGTCGTCCGCAGCGGCGTGAGGGGAGCGGCGGC
GGCGGCGGCGGCCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTCTCTCCGTGTGGCCCCC
TGAGCGGCCCCCCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCC
GCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGAATTAGC
AGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGA
TGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAG
AGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCG
ACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGA
TAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGA
GCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGT
ATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAA
TACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATA
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAG
CAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
CACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
AAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAATTTTTAGTAGGCACATCACGAAA
CTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTTTGGGGTCTTGCCACACATCCCTT
CAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGGCTGGAATGGACCAGGCTGGTAGA
TGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGA
AACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATAGATGGTACCTTCCTGGCTGTAGG
ATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGAAGGTGCACTGGACATTCCAGCTA
CATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATATTGTACTGGGACATTCCAAATGG
CTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTG
GCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGT
CCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGCCATGTCACCAATGTCAGTTTTAC
TCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAA
TGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCTAATACTCCCACACCGCCTCCTTC
TCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCC
AAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAAGAGCCATGCAACGAGATAAGCAA
GGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGCTTCAGTGCAACTCTTTTCCTTCA
GCTGCATGTGATTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATTGAGATTTTGGTTTCCATGTGATT
TGTTTTCTTCAATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTTTATTGAAAATTAACCAAACTTAA
TACTAGGAGAAGACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTAAATACTGGAAACAAAAACAGCAG
TTGCATTGATTTTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGTATCACAAACACTGTTACTCATCT
ACTGGCTCAGACTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTCTTACTGAGATACCCTCTCACCCC
AAATGTGTAATGGAAAATTTTTAATTAAGAAAAACTTCAGTTTTGCCAAGTGCAATGGTGTTGCCTTCTTTAAAAAATGCCGTTTTCTTA
CACTACCAGTGGATGTCCAGACATGCTCTTAGTCTACTAGAGAGGTGCTGCCTTTTCTAAGTCATAATGAGGAACAGTCCCTTAATTTCT
TGTGTGCAACTCTGTTTTATCCTAGAACTAAGAGAGCATTGGTTTGTTAAAGAGCTTTCAATGTATATTAAAACCTTCAATACTCAGAAA
TGATGGATTCCTCCAAGGAGTCCTTTACTAGCCTAAACATTCTCAAATGTTTGAGATTCAAGTGAATGGAAGGAAAACCACATGCCTTTA
AAACTAAACTGTAATAATTACCTGGCTAATTTCAGCTAAGCCTTCATCATAATTTGTTCCCTCAGTAATAGGAGAAATATAAATACAGTA
AGTTTAGATTATTGAATTGGTGCTTGAAATTTATTGGTTTTGTTGTAATTTTATACAGATTATATGAGGGATAAGATACTCATCAAATTG
CAAATTCTTTTTTTTACAGAAGTGTGGGTAACAGTCACAGCAGTTTTTTTTACCAACAGCATACTTAACAGACTTGCTGTGTAGCAGTTT
TTTTCTGGTGGAGTTGCTGTAAGTCTTGTAAGTCTAATGTGGCTATCCTACTCTTTTGGGCAATGCATGTATTATGCATTGGAAAGGTAT
TTTTTTTAAGTTCTGTTGGCTAGCTATGGTTTTCAGTACATTTCCTACTTTAAGAGTAATTACTGACAAATATGTATTTCCTATATGTTT
ATACTTTGATTATAAAAAAGTATTTTGTTTTGATTTTTTAACTTGCTGCATTGTTTTGATACTTTCTATTTTTTTGGTCAAATCATGTTT
AGAAACTTTGGATGAGTTAAGAAGTCTTAAGTATGCAGGCGTTTACGTGATTGTGCCATTCCAAAGTGCATCAGAACTGTCATTCCCTTC
TAATATCTTCTCAGGAGTAATACAAATCAGGTATTTCATCATCATTTGGTAATATGAAAACTCCAGTGAACTCCCAAGGACATTTACAAC
ATTTATATTCACACGCTGTATGGAAGGGTGTGGGTGTGTGTGAAGGGGCGAGTGGAGACACTGTGTGTATCTCTAGATAAGAAGATATGC
ACCACGTTGAAAATACTCAGTGTAGATCTCTATGTGTATAGGTATCTGTATATCTTTCCTTTTGTTTACAACTGTTAAAAAACCTCAAAA
TAGTTCTCTTCAAAAGAAGAGAGATTCCAAGCAACCCATCTTTCTTCAGTATGTATGTTCTGTACATACTTATCGGAGCGCGCCAGTAAG
TATCAGGCATATATATCTGTCTGTTAGCAATGATTATTACATCATCAGATCAGCATGTGCTATACTCCCTGCAAGAAATATACTGACATG
AACAGGCAGTTCTTGGAGAAGAAAGAGCATTTCTTTAAGTACCTGGGGAATACAGCTCTCAGTGATCAGCAGGGAGTTTATTTGAGGACA
TCAGTCACCTTTGGGGTTGCCATGTACAATGAGATTTATAATCATGATACTCTTCGGTGGTAGTTTCAAAAGACACTACTAATACGCAGG
AAGCGTTCCAGCTATTTAATGCTGGCAACTACTGTTTAATGGTCAGTTAAATCTGTGATAATGGTTGGAAGTGGGTGGGGTTATGAAATT
GTAGATGTTTTTAGAAAAACTTGTGAATGAAAATGAATCCAAGTGTTTCATGTGAAGATGTTGAGCCATTGCTATCATGCATTCCTGTCT

>In-frame_MAP4K3_ENST00000263881_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_3295nt
AAGGGGAGGGGGAGGAGCGGCGAAAGCGGAAGCCATGTTGGAGTTTCACCCCGAGCGAGGGGCTGCGAGGGTTCTCCTCTCCTTGTGGGT
GTGACCAGGTTCGGCGCGGCGGCGGGCCGCGGGGGGCGGGGACGATTGGCCGCTTGTCGTCGTCCGCAGCGGCGTGAGGGGAGCGGCGGC
GGCGGCGGCGGCCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTCTCTCCGTGTGGCCCCC
TGAGCGGCCCCCCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCC
GCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGAATTAGC
AGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGA
TGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAG
AGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCG
ACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGA
TAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGA
GCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGT
ATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAA
TACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATA
TGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAG
CAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTT
CACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGA
AAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAATTTTTAGTAGGCACATCACGAAA
CTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTTTGGGGTCTTGCCACACATCCCTT
CAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGGCTGGAATGGACCAGGCTGGTAGA
TGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGA
AACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATAGATGGTACCTTCCTGGCTGTAGG
ATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGAAGGTGCACTGGACATTCCAGCTA
CATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATATTGTACTGGGACATTCCAAATGG
CTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTG
GCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGT
CCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGCCATGTCACCAATGTCAGTTTTAC
TCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAA
TGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCTAATACTCCCACACCGCCTCCTTC
TCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCC
AAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAAGAGCCATGCAACGAGATAAGCAA
GGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGCTTCAGTGCAACTCTTTTCCTTCA
GCTGCATGTGATTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATTGAGATTTTGGTTTCCATGTGATT
TGTTTTCTTCAATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTTTATTGAAAATTAACCAAACTTAA
TACTAGGAGAAGACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTAAATACTGGAAACAAAAACAGCAG
TTGCATTGATTTTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGTATCACAAACACTGTTACTCATCT
ACTGGCTCAGACTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTCTTACTGAGATACCCTCTCACCCC

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_5088nt
GAGGAGCGGCGAAAGCGGAAGCCATGTTGGAGTTTCACCCCGAGCGAGGGGCTGCGAGGGTTCTCCTCTCCTTGTGGGTGTGACCAGGTT
CGGCGCGGCGGCGGGCCGCGGGGGGCGGGGACGATTGGCCGCTTGTCGTCGTCCGCAGCGGCGTGAGGGGAGCGGCGGCGGCGGCGGCGG
CCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTCTCTCCGTGTGGCCCCCTGAGCGGCCCC
CCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACT
TCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAG
TAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACT
ATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTT
ACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGG
GCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAA
GGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAG
GATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGC
AGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTA
CATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAA
AATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTG
TAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTC
AGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAG
AGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTAC
GAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGC
TCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGAC
ACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATC
TAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACA
ACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACC
TTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAA
TCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGAT
CTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTC
AGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACA
GTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAG
CGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAA
ATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACC
ACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCA
AAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGCTTCAGTGCAACTCTTTTCCTTCAGCTGCATGTGA
TTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATTGAGATTTTGGTTTCCATGTGATTTGTTTTCTTCA
ATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTTTATTGAAAATTAACCAAACTTAATACTAGGAGAA
GACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTAAATACTGGAAACAAAAACAGCAGTTGCATTGATT
TTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGTATCACAAACACTGTTACTCATCTACTGGCTCAGA
CTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTCTTACTGAGATACCCTCTCACCCCAAATGTGTAAT
GGAAAATTTTTAATTAAGAAAAACTTCAGTTTTGCCAAGTGCAATGGTGTTGCCTTCTTTAAAAAATGCCGTTTTCTTACACTACCAGTG
GATGTCCAGACATGCTCTTAGTCTACTAGAGAGGTGCTGCCTTTTCTAAGTCATAATGAGGAACAGTCCCTTAATTTCTTGTGTGCAACT
CTGTTTTATCCTAGAACTAAGAGAGCATTGGTTTGTTAAAGAGCTTTCAATGTATATTAAAACCTTCAATACTCAGAAATGATGGATTCC
TCCAAGGAGTCCTTTACTAGCCTAAACATTCTCAAATGTTTGAGATTCAAGTGAATGGAAGGAAAACCACATGCCTTTAAAACTAAACTG
TAATAATTACCTGGCTAATTTCAGCTAAGCCTTCATCATAATTTGTTCCCTCAGTAATAGGAGAAATATAAATACAGTAAGTTTAGATTA
TTGAATTGGTGCTTGAAATTTATTGGTTTTGTTGTAATTTTATACAGATTATATGAGGGATAAGATACTCATCAAATTGCAAATTCTTTT
TTTTACAGAAGTGTGGGTAACAGTCACAGCAGTTTTTTTTACCAACAGCATACTTAACAGACTTGCTGTGTAGCAGTTTTTTTCTGGTGG
AGTTGCTGTAAGTCTTGTAAGTCTAATGTGGCTATCCTACTCTTTTGGGCAATGCATGTATTATGCATTGGAAAGGTATTTTTTTTAAGT
TCTGTTGGCTAGCTATGGTTTTCAGTACATTTCCTACTTTAAGAGTAATTACTGACAAATATGTATTTCCTATATGTTTATACTTTGATT
ATAAAAAAGTATTTTGTTTTGATTTTTTAACTTGCTGCATTGTTTTGATACTTTCTATTTTTTTGGTCAAATCATGTTTAGAAACTTTGG
ATGAGTTAAGAAGTCTTAAGTATGCAGGCGTTTACGTGATTGTGCCATTCCAAAGTGCATCAGAACTGTCATTCCCTTCTAATATCTTCT
CAGGAGTAATACAAATCAGGTATTTCATCATCATTTGGTAATATGAAAACTCCAGTGAACTCCCAAGGACATTTACAACATTTATATTCA
CACGCTGTATGGAAGGGTGTGGGTGTGTGTGAAGGGGCGAGTGGAGACACTGTGTGTATCTCTAGATAAGAAGATATGCACCACGTTGAA
AATACTCAGTGTAGATCTCTATGTGTATAGGTATCTGTATATCTTTCCTTTTGTTTACAACTGTTAAAAAACCTCAAAATAGTTCTCTTC
AAAAGAAGAGAGATTCCAAGCAACCCATCTTTCTTCAGTATGTATGTTCTGTACATACTTATCGGAGCGCGCCAGTAAGTATCAGGCATA
TATATCTGTCTGTTAGCAATGATTATTACATCATCAGATCAGCATGTGCTATACTCCCTGCAAGAAATATACTGACATGAACAGGCAGTT
CTTGGAGAAGAAAGAGCATTTCTTTAAGTACCTGGGGAATACAGCTCTCAGTGATCAGCAGGGAGTTTATTTGAGGACATCAGTCACCTT
TGGGGTTGCCATGTACAATGAGATTTATAATCATGATACTCTTCGGTGGTAGTTTCAAAAGACACTACTAATACGCAGGAAGCGTTCCAG
CTATTTAATGCTGGCAACTACTGTTTAATGGTCAGTTAAATCTGTGATAATGGTTGGAAGTGGGTGGGGTTATGAAATTGTAGATGTTTT
TAGAAAAACTTGTGAATGAAAATGAATCCAAGTGTTTCATGTGAAGATGTTGAGCCATTGCTATCATGCATTCCTGTCTCATGGCAGAAA

>In-frame_MAP4K3_ENST00000341681_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_3284nt
GAGGAGCGGCGAAAGCGGAAGCCATGTTGGAGTTTCACCCCGAGCGAGGGGCTGCGAGGGTTCTCCTCTCCTTGTGGGTGTGACCAGGTT
CGGCGCGGCGGCGGGCCGCGGGGGGCGGGGACGATTGGCCGCTTGTCGTCGTCCGCAGCGGCGTGAGGGGAGCGGCGGCGGCGGCGGCGG
CCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTCTCTCCGTGTGGCCCCCTGAGCGGCCCC
CCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACT
TCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGAATTAGCAGCAATTAAAG
TAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCAATTACCATGTTCATTCCTTCCGATGTTGACAACT
ATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATATGGTTATCGAGGAAAGGACTGTAGAGCTAATGTTT
ACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTTAATTATGAGGAGAGAACTCAGCGACACTACCTGG
GCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCAACTGGACAGATAGCTGGCGTGGATAAAGATGGAA
GGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAGATTATTGGACTTGGCACTTTTGAGCGTGGAGTAG
GATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGACTCCAATGAGCATATGCTTACTGTATGGGACTGGC
AGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTGGAGTTTCACCCAACAGATGCAAATACCATAATTA
CATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGAAAACAGGGAATTTTTGGGAAATATGAAAAGCCAA
AATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCAGGTGGAGTCATGCTTATATGGAGCAAAACTACTG
TAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATCAAAGCTCATGATGGCAGTGTGTTCACACTTTGTC
AGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTGTGGGATCATGATCTGAATCCTGAAAGAGAAATAG
AGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAATTTTTAGTAGGCACATCACGAAACTTTATTTTAC
GAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTTTGGGGTCTTGCCACACATCCCTTCAAAGATTTGC
TCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGGCTGGAATGGACCAGGCTGGTAGATGAACCAGGAC
ACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGCAGGTGGTTTGTTCTGGATGCAGAAACCAGAGATC
TAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATAGATGGTACCTTCCTGGCTGTAGGATCTCATGACA
ACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGAAGGTGCACTGGACATTCCAGCTACATCACACACC
TTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATATTGTACTGGGACATTCCAAATGGCTGCAAACTAA
TCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTAGGATTTCAAGTATTTGGTGTCTGGCCAGAAGGAT
CTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCTGTTGCCGATGACTTTTGTAAAGTCCATCTGTTTC
AGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGCCATGTCACCAATGTCAGTTTTACTCACAATGACA
GTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTGGAAAAGTTATCTTTGCCTCAGAATGAGACTGTAG
CGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCTAATACTCCCACACCGCCTCCTTCTCAGCCCTTAA
ATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAACAGCCTGGAACAAACTGTGGAGCCAAGTGAAGACC
ACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAAGAGCCATGCAACGAGATAAGCAAGGAGCAGGCCA
AAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGCTTCAGTGCAACTCTTTTCCTTCAGCTGCATGTGA
TTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATTGAGATTTTGGTTTCCATGTGATTTGTTTTCTTCA
ATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTTTATTGAAAATTAACCAAACTTAATACTAGGAGAA
GACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTAAATACTGGAAACAAAAACAGCAGTTGCATTGATT
TTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGTATCACAAACACTGTTACTCATCTACTGGCTCAGA
CTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTCTTACTGAGATACCCTCTCACCCCAAATGTGTAAT

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000318522_chr2_42507990_+_4852nt
CGCCCTCTCTCCGTGTGGCCCCCTGAGCGGCCCCCCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGC
TTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGG
AATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCA
ATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATAT
GGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTT
AATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCA
ACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAG
ATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGAC
TCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTG
GAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGA
AAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCA
GGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
AAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTG
TGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAA
TTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTT
TGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGG
CTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGC
AGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATA
GATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGA
AGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATA
TTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTA
GGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCT
GTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGC
CATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTG
GAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCT
AATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAAC
AGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAA
GAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGC
TTCAGTGCAACTCTTTTCCTTCAGCTGCATGTGATTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATT
GAGATTTTGGTTTCCATGTGATTTGTTTTCTTCAATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTT
TATTGAAAATTAACCAAACTTAATACTAGGAGAAGACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTA
AATACTGGAAACAAAAACAGCAGTTGCATTGATTTTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGT
ATCACAAACACTGTTACTCATCTACTGGCTCAGACTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTC
TTACTGAGATACCCTCTCACCCCAAATGTGTAATGGAAAATTTTTAATTAAGAAAAACTTCAGTTTTGCCAAGTGCAATGGTGTTGCCTT
CTTTAAAAAATGCCGTTTTCTTACACTACCAGTGGATGTCCAGACATGCTCTTAGTCTACTAGAGAGGTGCTGCCTTTTCTAAGTCATAA
TGAGGAACAGTCCCTTAATTTCTTGTGTGCAACTCTGTTTTATCCTAGAACTAAGAGAGCATTGGTTTGTTAAAGAGCTTTCAATGTATA
TTAAAACCTTCAATACTCAGAAATGATGGATTCCTCCAAGGAGTCCTTTACTAGCCTAAACATTCTCAAATGTTTGAGATTCAAGTGAAT
GGAAGGAAAACCACATGCCTTTAAAACTAAACTGTAATAATTACCTGGCTAATTTCAGCTAAGCCTTCATCATAATTTGTTCCCTCAGTA
ATAGGAGAAATATAAATACAGTAAGTTTAGATTATTGAATTGGTGCTTGAAATTTATTGGTTTTGTTGTAATTTTATACAGATTATATGA
GGGATAAGATACTCATCAAATTGCAAATTCTTTTTTTTACAGAAGTGTGGGTAACAGTCACAGCAGTTTTTTTTACCAACAGCATACTTA
ACAGACTTGCTGTGTAGCAGTTTTTTTCTGGTGGAGTTGCTGTAAGTCTTGTAAGTCTAATGTGGCTATCCTACTCTTTTGGGCAATGCA
TGTATTATGCATTGGAAAGGTATTTTTTTTAAGTTCTGTTGGCTAGCTATGGTTTTCAGTACATTTCCTACTTTAAGAGTAATTACTGAC
AAATATGTATTTCCTATATGTTTATACTTTGATTATAAAAAAGTATTTTGTTTTGATTTTTTAACTTGCTGCATTGTTTTGATACTTTCT
ATTTTTTTGGTCAAATCATGTTTAGAAACTTTGGATGAGTTAAGAAGTCTTAAGTATGCAGGCGTTTACGTGATTGTGCCATTCCAAAGT
GCATCAGAACTGTCATTCCCTTCTAATATCTTCTCAGGAGTAATACAAATCAGGTATTTCATCATCATTTGGTAATATGAAAACTCCAGT
GAACTCCCAAGGACATTTACAACATTTATATTCACACGCTGTATGGAAGGGTGTGGGTGTGTGTGAAGGGGCGAGTGGAGACACTGTGTG
TATCTCTAGATAAGAAGATATGCACCACGTTGAAAATACTCAGTGTAGATCTCTATGTGTATAGGTATCTGTATATCTTTCCTTTTGTTT
ACAACTGTTAAAAAACCTCAAAATAGTTCTCTTCAAAAGAAGAGAGATTCCAAGCAACCCATCTTTCTTCAGTATGTATGTTCTGTACAT
ACTTATCGGAGCGCGCCAGTAAGTATCAGGCATATATATCTGTCTGTTAGCAATGATTATTACATCATCAGATCAGCATGTGCTATACTC
CCTGCAAGAAATATACTGACATGAACAGGCAGTTCTTGGAGAAGAAAGAGCATTTCTTTAAGTACCTGGGGAATACAGCTCTCAGTGATC
AGCAGGGAGTTTATTTGAGGACATCAGTCACCTTTGGGGTTGCCATGTACAATGAGATTTATAATCATGATACTCTTCGGTGGTAGTTTC
AAAAGACACTACTAATACGCAGGAAGCGTTCCAGCTATTTAATGCTGGCAACTACTGTTTAATGGTCAGTTAAATCTGTGATAATGGTTG
GAAGTGGGTGGGGTTATGAAATTGTAGATGTTTTTAGAAAAACTTGTGAATGAAAATGAATCCAAGTGTTTCATGTGAAGATGTTGAGCC

>In-frame_MAP4K3_ENST00000484274_chr2_39605207_-_EML4_ENST00000402711_chr2_42507990_+_3048nt
CGCCCTCTCTCCGTGTGGCCCCCTGAGCGGCCCCCCTCCCCTGCCCGGGAGGGAGGCGGGGGGCACCTGGGGCCCGCCATGAACCCCGGC
TTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGATTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGG
AATGTTAACACTGGTGAATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGAAGGAGAATATATTAAAATGTTTATGCGCGGTCGGCCA
ATTACCATGTTCATTCCTTCCGATGTTGACAACTATGATGACATCAGAACGGAACTGCCTCCTGAGAAGCTCAAACTGGAGTGGGCATAT
GGTTATCGAGGAAAGGACTGTAGAGCTAATGTTTACCTTCTTCCGACCGGGAAAATAGTTTATTTCATTGCATCAGTAGTAGTACTATTT
AATTATGAGGAGAGAACTCAGCGACACTACCTGGGCCATACAGACTGTGTGAAATGCCTTGCTATACATCCTGACAAAATTAGGATTGCA
ACTGGACAGATAGCTGGCGTGGATAAAGATGGAAGGCCTCTACAACCCCACGTCAGAGTGTGGGATTCTGTTACTCTATCCACACTGCAG
ATTATTGGACTTGGCACTTTTGAGCGTGGAGTAGGATGCCTGGATTTTTCAAAAGCAGATTCAGGTGTTCATTTATGTATTATTGATGAC
TCCAATGAGCATATGCTTACTGTATGGGACTGGCAGAAGAAAGCAAAAGGAGCAGAAATAAAGACAACAAATGAAGTTGTTTTGGCTGTG
GAGTTTCACCCAACAGATGCAAATACCATAATTACATGCGGTAAATCTCATATTTTCTTCTGGACCTGGAGCGGCAATTCACTAACAAGA
AAACAGGGAATTTTTGGGAAATATGAAAAGCCAAAATTTGTGCAGTGTTTAGCATTCTTGGGGAATGGAGATGTTCTTACTGGAGACTCA
GGTGGAGTCATGCTTATATGGAGCAAAACTACTGTAGAGCCCACACCTGGGAAAGGACCTAAAGGTGTATATCAAATCAGCAAACAAATC
AAAGCTCATGATGGCAGTGTGTTCACACTTTGTCAGATGAGAAATGGGATGTTATTAACTGGAGGAGGGAAAGACAGAAAAATAATTCTG
TGGGATCATGATCTGAATCCTGAAAGAGAAATAGAGGTTCCTGATCAGTATGGCACAATCAGAGCTGTAGCAGAAGGAAAGGCAGATCAA
TTTTTAGTAGGCACATCACGAAACTTTATTTTACGAGGAACATTTAATGATGGCTTCCAAATAGAAGTACAGGGTCATACAGATGAGCTT
TGGGGTCTTGCCACACATCCCTTCAAAGATTTGCTCTTGACATGTGCTCAGGACAGGCAGGTGTGCCTGTGGAACTCAATGGAACACAGG
CTGGAATGGACCAGGCTGGTAGATGAACCAGGACACTGTGCAGATTTTCATCCAAGTGGCACAGTGGTGGCCATAGGAACGCACTCAGGC
AGGTGGTTTGTTCTGGATGCAGAAACCAGAGATCTAGTTTCTATCCACACAGACGGGAATGAACAGCTCTCTGTGATGCGCTACTCAATA
GATGGTACCTTCCTGGCTGTAGGATCTCATGACAACTTTATTTACCTCTATGTAGTCTCTGAAAATGGAAGAAAATATAGCAGATATGGA
AGGTGCACTGGACATTCCAGCTACATCACACACCTTGACTGGTCCCCAGACAACAAGTATATAATGTCTAACTCGGGAGACTATGAAATA
TTGTACTGGGACATTCCAAATGGCTGCAAACTAATCAGGAATCGATCGGATTGTAAGGACATTGATTGGACGACATATACCTGTGTGCTA
GGATTTCAAGTATTTGGTGTCTGGCCAGAAGGATCTGATGGGACAGATATCAATGCACTGGTGCGATCCCACAATAGAAAGGTGATAGCT
GTTGCCGATGACTTTTGTAAAGTCCATCTGTTTCAGTATCCCTGCTCCAAAGCAAAGGCTCCCAGTCACAAGTACAGTGCCCACAGCAGC
CATGTCACCAATGTCAGTTTTACTCACAATGACAGTCACCTGATATCAACTGGTGGAAAAGACATGAGCATCATTCAGTGGAAACTTGTG
GAAAAGTTATCTTTGCCTCAGAATGAGACTGTAGCGGATACTACTCTAACCAAAGCCCCCGTCTCTTCCACTGAAAGTGTCATCCAATCT
AATACTCCCACACCGCCTCCTTCTCAGCCCTTAAATGAGACAGCTGAAGAGGAAAGTAGAATAAGCAGTTCTCCCACACTTCTGGAGAAC
AGCCTGGAACAAACTGTGGAGCCAAGTGAAGACCACAGCGAGGAGGAGAGTGAAGAGGGCAGCGGAGACCTTGGTGAGCCTCTTTATGAA
GAGCCATGCAACGAGATAAGCAAGGAGCAGGCCAAAGCCACCCTTCTGGAGGACCAGCAAGACCCTTCGCCCTCGTCCTAACACCCTGGC
TTCAGTGCAACTCTTTTCCTTCAGCTGCATGTGATTTTGTGATAAAGTTCAGGTAACAGGATGGGCAGTGATGGAGAATCACTGTTGATT
GAGATTTTGGTTTCCATGTGATTTGTTTTCTTCAATAGTCTTATTTTCAGTCTCTCAAATACAGCCAACTTAAAGTTTTAGTTTGGTGTT
TATTGAAAATTAACCAAACTTAATACTAGGAGAAGACTGAATCATTAATGATGTCTCACAAATTACTGTGTACCTAAGTGGTGTGATGTA
AATACTGGAAACAAAAACAGCAGTTGCATTGATTTTGAAAACAAACCCCCTTGTTATCTGAACATGTTTTCTTCAGGAACAACCAGAGGT
ATCACAAACACTGTTACTCATCTACTGGCTCAGACTGTACTACTTTTTTTTTTTTTTTTCCTGAAAAAGAAACCAGAAAAAAATGTACTC


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FusionGenePPI for MAP4K3_EML4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
MAP4K3GRB2, SORBS1, COPS5, ITSN2, SH3RF1, PCBP1, NTRK1, GAN, IL13RA1, VAPB, MAP4K5EML4NEK6, ARL4D, ARIH2, ELAVL1, EML4, ILK, PRPS1, TUBB2A, TUBB2B, FBXW11, NTRK1, SPICE1, DCTN1, TFEB, NUDC, EML1, FBXO28, TUBB3, CTAGE5, TUBB, TKT, PHKG2, NEK7


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for MAP4K3_EML4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MAP4K3_EML4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneEML4C0007131Non-Small Cell Lung Carcinoma6CTD_human
TgeneEML4C0027627Neoplasm Metastasis2CTD_human
TgeneEML4C0152013Adenocarcinoma of lung (disorder)2CTD_human
TgeneEML4C0006118Brain Neoplasms1CTD_human