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Fusion gene ID: 20745 |
FusionGeneSummary for MAN1A2_VANGL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAN1A2_VANGL1 | Fusion gene ID: 20745 | Hgene | Tgene | Gene symbol | MAN1A2 | VANGL1 | Gene ID | 10905 | 81839 |
| Gene name | mannosidase alpha class 1A member 2 | VANGL planar cell polarity protein 1 | |
| Synonyms | MAN1B | KITENIN|LPP2|STB2|STBM2 | |
| Cytomap | 1p12 | 1p13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mannosyl-oligosaccharide 1,2-alpha-mannosidase IBalpha-1,2-mannosidase IBalpha1,2-mannosidaseprocessing alpha-1,2-mannosidase IB | vang-like protein 1KAI1 C-terminal interacting tetraspaninloop-tail protein 2 homologstrabismus 2van Gogh-like protein 1vang-like 1 (van gogh, Drosophila) | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | O60476 | Q8TAA9 | |
| Ensembl transtripts involved in fusion gene | ENST00000356554, ENST00000482811, | ENST00000355485, ENST00000369510, ENST00000310260, ENST00000369509, ENST00000474344, | |
| Fusion gene scores | * DoF score | 11 X 12 X 6=792 | 6 X 5 X 4=120 |
| # samples | 19 | 6 | |
| ** MAII score | log2(19/792*10)=-2.05950101174866 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAN1A2 [Title/Abstract] AND VANGL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A8-A0A6-01A | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000356554 | ENST00000355485 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| In-frame | ENST00000356554 | ENST00000369510 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| In-frame | ENST00000356554 | ENST00000310260 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| In-frame | ENST00000356554 | ENST00000369509 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| 5CDS-3UTR | ENST00000356554 | ENST00000474344 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| intron-3CDS | ENST00000482811 | ENST00000355485 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| intron-3CDS | ENST00000482811 | ENST00000369510 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| intron-3CDS | ENST00000482811 | ENST00000310260 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| intron-3CDS | ENST00000482811 | ENST00000369509 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
| intron-3UTR | ENST00000482811 | ENST00000474344 | MAN1A2 | chr1 | 117984947 | + | VANGL1 | chr1 | 116224985 | + |
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FusionProtFeatures for MAN1A2_VANGL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAN1A2 | VANGL1 |
| Involved in the maturation of Asn-linkedoligosaccharides. Progressively trim alpha-1,2-linked mannoseresidues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MAN1A2 | chr1:117984947 | chr1:116224985 | ENST00000356554 | + | 6 | 13 | 2_36 | 316 | 642 | Topological domain | Cytoplasmic |
| Hgene | MAN1A2 | chr1:117984947 | chr1:116224985 | ENST00000356554 | + | 6 | 13 | 37_57 | 316 | 642 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >MAN1A2 | chr1:117984947 | chr1:116224985 | ENST00000356554 | + | 6 | 13 | 58_641 | 316 | 642 | Topological domain | Lumenal |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 139_151 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 173_182 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 1_117 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 204_222 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 244_524 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 139_151 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 173_182 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 1_117 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 204_222 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 244_524 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 139_151 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 173_182 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 1_117 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 204_222 | 270 | 525 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 244_524 | 270 | 525 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 139_151 | 268 | 523 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 173_182 | 268 | 523 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 1_117 | 268 | 523 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 204_222 | 268 | 523 | Topological domain | Extracellular |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 244_524 | 268 | 523 | Topological domain | Cytoplasmic |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 118_138 | 270 | 525 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 152_172 | 270 | 525 | Transmembrane | Helical%3B Name%3D2 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 183_203 | 270 | 525 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000310260 | + | 3 | 8 | 223_243 | 270 | 525 | Transmembrane | Helical%3B Name%3D4 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 118_138 | 270 | 525 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 152_172 | 270 | 525 | Transmembrane | Helical%3B Name%3D2 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 183_203 | 270 | 525 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000355485 | + | 3 | 8 | 223_243 | 270 | 525 | Transmembrane | Helical%3B Name%3D4 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 118_138 | 270 | 525 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 152_172 | 270 | 525 | Transmembrane | Helical%3B Name%3D2 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 183_203 | 270 | 525 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369509 | + | 2 | 7 | 223_243 | 270 | 525 | Transmembrane | Helical%3B Name%3D4 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 118_138 | 268 | 523 | Transmembrane | Helical%3B Name%3D1 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 152_172 | 268 | 523 | Transmembrane | Helical%3B Name%3D2 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 183_203 | 268 | 523 | Transmembrane | Helical%3B Name%3D3 |
| Tgene | VANGL1 | chr1:117984947 | chr1:116224985 | ENST00000369510 | + | 3 | 8 | 223_243 | 268 | 523 | Transmembrane | Helical%3B Name%3D4 |
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FusionGeneSequence for MAN1A2_VANGL1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000355485_chr1_116224985_+_571aa MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR FIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNV DGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARA LQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNV >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369510_chr1_116224985_+_571aa MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR FIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNV DGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARA LQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNV >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000310260_chr1_116224985_+_571aa MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR FIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNV DGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARA LQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNV >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369509_chr1_116224985_+_571aa MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVF LIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREK REKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIR FIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNV DGPSNNATGQSRAMIAAAARRRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARA LQKYLRITRQQNYHSMESILQHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000355485_chr1_116224985_+_1713nt ATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCACATCACAGGGCTACC TTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTTTTCCTTCCAGACTCT TCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAAAACCCCGGAGTCTTC CTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCATGAGAAGGCCTTGGAA GAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTCCAAGAAATGAAGATA AAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAATGACATAAGAGAGAAA AGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTCAGACCTATTGCAAGG AAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTATATCATGGGACTTCAT GATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTTGAAGTCAACATTCGA TTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCTGAGAAACTCCTTCCT GCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTCCTAGAAAATTACTAC AAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAAGTCTACAATGTA GATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCACAACGAGTTGTAT TATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATCCACATTCAGCGT CTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCCATGGCCAGGGCT CTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGCATCACCAACGGC ATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCTACACAGTGGAGG CTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTCGTAGTCAATGTG AAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCTGAGACATCCGTT >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369510_chr1_116224985_+_1713nt ATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCACATCACAGGGCTACC TTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTTTTCCTTCCAGACTCT TCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAAAACCCCGGAGTCTTC CTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCATGAGAAGGCCTTGGAA GAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTCCAAGAAATGAAGATA AAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAATGACATAAGAGAGAAA AGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTCAGACCTATTGCAAGG AAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTATATCATGGGACTTCAT GATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTTGAAGTCAACATTCGA TTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCTGAGAAACTCCTTCCT GCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTCCTAGAAAATTACTAC AAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAAGTCTACAATGTA GATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCACAACGAGTTGTAT TATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATCCACATTCAGCGT CTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCCATGGCCAGGGCT CTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGCATCACCAACGGC ATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCTACACAGTGGAGG CTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTCGTAGTCAATGTG AAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCTGAGACATCCGTT >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000310260_chr1_116224985_+_1713nt ATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCACATCACAGGGCTACC TTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTTTTCCTTCCAGACTCT TCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAAAACCCCGGAGTCTTC CTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCATGAGAAGGCCTTGGAA GAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTCCAAGAAATGAAGATA AAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAATGACATAAGAGAGAAA AGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTCAGACCTATTGCAAGG AAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTATATCATGGGACTTCAT GATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTTGAAGTCAACATTCGA TTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCTGAGAAACTCCTTCCT GCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTCCTAGAAAATTACTAC AAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAAGTCTACAATGTA GATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCACAACGAGTTGTAT TATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATCCACATTCAGCGT CTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCCATGGCCAGGGCT CTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGCATCACCAACGGC ATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCTACACAGTGGAGG CTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTCGTAGTCAATGTG AAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCTGAGACATCCGTT >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369509_chr1_116224985_+_1713nt ATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCACATCACAGGGCTACC TTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTTTTCCTTCCAGACTCT TCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAAAACCCCGGAGTCTTC CTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCATGAGAAGGCCTTGGAA GAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTCCAAGAAATGAAGATA AAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAATGACATAAGAGAGAAA AGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTCAGACCTATTGCAAGG AAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTATATCATGGGACTTCAT GATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTTGAAGTCAACATTCGA TTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCTGAGAAACTCCTTCCT GCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTCCTAGAAAATTACTAC AAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAAGTCTACAATGTA GATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCACAACGAGTTGTAT TATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATCCACATTCAGCGT CTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCCATGGCCAGGGCT CTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGCATCACCAACGGC ATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCTACACAGTGGAGG CTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTCGTAGTCAATGTG AAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCTGAGACATCCGTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000355485_chr1_116224985_+_9293nt AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCT GAGAAACTCCTTCCTGCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTC CTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTG AAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGC CACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTC ATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCC TCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTC TGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTC TCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGC CTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAG TCTGAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGG GTGTCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAG GAAGCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTT CTGTTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCC CCGTTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGT ATTTGTGTATGTTAATGTCCAGTATCACATCACCCATGAAAGTCGTGGGCAGTTCAGGAGATACCTGCCTTCATCTTTGTTCTTTGTTGC CTTAGGTTCTTCAGAGAAAGATCACAACAAAAAATGTACACTGTCGTTTACAGCTATTAAGTGATTTGATTTTGTTTTTTTCCCAAAGAG AAAACCTACCTGCCCTGTTTCTGATCCCACCCCTCTGCTGGCTTGAAGCAGGTAACCCTTTCCCAGCCCTGCAGCTGCCCACCTGGCCTC CATGCCATCCTGCCCCCACCTGGCTGGCAGCCCTGGCTCTCCATGTGTGCCCTCCGGCTCTGTGTGAAGCCTCAAGTCAGTCCCAGCATT GTTTCCATAGGGAAGTGTGGGGTGCCCAGCAGGTAAAGCACAGGGAGAGAGGGCAGTGGGAATGCCACCTTTAGGCTGCAGCAGGAGCCC CACACTGCCCAGTTTTCCTCCCCACTGTTCTACACCAACCAGGGGAGACTAACACTGTGACTCTGGGATTGGCAGGTGCAACTTGGAGCC ACTTAATTTCCTGGGGACGTAAGTTCTTCCCAAGCTTAGAGCAAGCTGCCCTGCCAAAGGAGACCAAACCATGCCAACCACGCTGGCAAC TGCTGCTGTCCAGTCCCTGTGTTTTCTGACCACCGTCACTGTGCAACTCATCGCCTCTGCCACTTAGGACCAGGAAAGAGGCTGGTTTTG CTCCCACTCTTAGTTGCTGATAAAGTGGGGAGAAGGAAAATGGACACTCTACAGAGTTTGGGGAAGGGAGAGTAGGGAGCCCATCTTGTC CAGAAAGATTCATCTGTGGTCTGTCTGTTAAACACAGCTGATTTCAGTGGGCTTTCCCCTGGCCCTGGGGGAGCAGACACTGACTGGGTT GTGGGCAGAGGAGCCATCCTGGCGGAGCCCTGCTGCAGGGGAGCTCCTTCAGGAGCCCCATCCGGACCTCTTGCACTGGGCTGCCTTTGC CTCCATTTGCCTTCCTGTATCTGCAACAAACCTTTTAAAAGTGTTCACTCTTGCTTTTTCCAGTATTTCGGTAATCAGCCATCTTGCTGT AGTACAGGATGACATTGTCGAATGCTCTTTGTATGTGTGCACACCCCCTTACTCCCTTACTGCTTCATACACTCCACAAGTGGTACAGTA TTTTGTGTCATTGTAAAAATCAAAATTGGCTTTGGATCTTTGTAATACACCTGTACCTGAAAAAGTAAACAACATTCTTCAATTACTAGC CTTCAGCTTGAAAAGACATGCTGGAGAAGAAGGAAGGGGGAACCCATAGGTGTGGCGTGGAGCCAAGATGTACTATTCAACTATGTGTTT CTGTTTATAAAAAACACATACCATGGAACCATGGTGCTTTTGTTCTTAGTTTTTGCCGTTAGATCCCTTCAAACTGGAAGTTCCTTACAA TATCTTTCTCAGGAAATATTTTGGGAAATGGGGTAAGAGATGGCAAGTGTGAGACGGGCTGTGTCAGAGGTTGCTACGTCATGGATACAG TGCAGTTCCAAGTGCCATAAGTGTATGTACATATAGTTAATAATGACACTGTTCATCACCATTCTAAAATACTGTTCTTCCAACCCTATC TTCAATGACCAGTCCAGAAGGGGTTAAGCTGGATTCATTTGCTCTGGCATGTGCATTCCCAGCAGGGTGAAGAAAGGTTTAAATTAAAGA ATTTATTTTCTCTCTCCCCCTTCCTCTTTCTCCCAGTCTTTGCATAGGAGAATGTTAGACATTCAGAAATTACTGTTTCTGTTTTAAATT GAGTATTGATTTTTTTATATTGACTTTGTATTGAGTTCTTTTTGAAAGAATAACAAAATAAAATGCAGGATCTTTGTAAAGCCTTTGCAC TTTCAACCTCTTTATAGCTTGAGTTACTTTTGCAGTGGGAACAATGTAAATGACATTTAAAAGATTTAAGGTTTCAGAAAGCTGCATCCC ACAATTGAACACAATGCATTTTTATTTCAATTCTTGGAACTGGTAGGCTATTCTTTTTAAAAGGGGGTAAACTTCGCCCTAAGGCTGGTA GAATGTATGTTCACATTATAGTAGACAGGATTTCATTTGCCTTATATGTTTATAGATTTTTTATAATTTTCATCCTACGTTATTAAAATT AGAGCATTGAGTGTTAAAGAACTTAATGAGGAGTCTATATCTGAGATTGCTCTCTTCCCTGGTGATGTTTTAACTGGTAGATAATTTGTT CTTAAATATGTACTTTTGAAGATAGGACAGTTTTTATAGTCCATGAACTGAATGTTAAAAAGTTCTGTATGCATTCTCAGAGAGGATTTT AAAGCTATATAGTTCATCCATCCTTTGCATTATCAAAATGTTAAGTCAAATCTGTAATACTTTGGCTAAAATTCATAAAGTAAGCCCTAG AGAAAATACTTGACCACCAAATTTTTGCCCAACTATCATCACCTCCCTTCCCCCGCCTCTGTTCTTGCCTTTTGACATCTACATGGAAGA CAAGTTCTTTACAGCAAATGGTAAGAGGCAGGTGACCTGGTGTGTTTGCTGTGTTGTAGTTCATTGCCTGGGGCTTGGGACTCCTTTTTT AATGGAGAGACTAGCTGTGCAGGTGTGTGTTGGATAGGGATAAAGTGCTCACCCCTGCCCTCTCTACAGTAGTTGGTGGTAGATTTCTCT CTCATTTTGCCTCATAATCACTTTCGAGTGCATGTATTTACCTAAGGGCTGTAGCTCTGTGGGATGCTACCAGCATATTGGACTGACAGA AATTGATTACCTTGCCACTCCAACCTACGTACTGAGTGAGTGCTCCAGCCACTCAGTGAAACCAACAAAAGTGAGTCCTTGGTTTACCTT CCAATCTGGGTCCTGCTGTGTAAGTATCCCTAAGTGGGGATGCATATTTGTTTGTGCGTTTTTATTTCCATATATGTGAGCATTTCTCTG AGTGTATTACCAGACGGATAGCACATTTATATGTCAGACATCTTAACATCTGTGTTATCTGTAGCAGGTGTGTAGCTCAGCAGATACGTG TCATTGTGTATATAGCTGAGTGTGTGAGGGTGTCTGTGTTTCTGCAGTCCCCTGTGTTTGAGAGATGACTTAATAACCCTGTGTTTTGAG AGGTCGCTCTAAACCAGTGACTTTTCCCTCCCCTGCTTTATTCCTTTCCCTCACTGACACTGGCTTCTCCCGCTAGAGTAAATGGCTTTA GCACAGCACTGTCTTCTGGGGAGCCTGCTGTCCTGCAGGCAAGTCCATTAAACTCTTTCTTGCTTTAGGACTCTGAAAACAGCAAGAAAC AAACAAACAAAGGTCAAGCTCTAAGAAAATTACTGCTCAAACTTCACTACCCTGGAAGCCTTACTAGATATTTCTTAAGGTAACTTAAAA ATTGGGCTTTATTTTTAAAAAGTGATAGGTTACTTACAGTAGCACAGAAATGTTAGCATATTTATTTAAATAGTCCTGCAGCAGAGACCC TGCGATTGTAAAGTGATTTAAGTATTTCTGGGTAGTGTTTGTGATTTACGGATTTGTTACTGAAAAACAAAAAAATCACTACTGTGAATT TACTACTATGTAACCTTGTGGTCGTATTTCATTATAAATAAAATAAGAATTGCTCTTCTGCCCACCGTTCTTGATTGGTATTCAGTGCAG TAGCGAAATGAGATAGTTTAGACACTGTTGAAATAACTGCATTGAGCTTTAACCAAGTGTATGCTCAGAAAATTCAGTTTTGGATCACAT TTTGACAAAACATGTTTTGGTCAAAGAAAGGAAAGGCTACTAACACATTTATCAGGTAATGTATGTCACAGTCCGTGTTCCACCCAGCCT TGTTATCCCCACATTCTTTCAAGATAGGAGTCATCTTGGTTTTTCGGGTGAAAAACGGAAGGTCAGAGAGGAAGGGGCTTGTCCAAGGTC TCATGTCTGGTTAACAGAATTTCAAACTAGATGTTTGATTCTAACCCCTCAGTCCACTGTACCTTGAAGTATGGTCTAAATGATTCGGCA CTTCTGGATGTTGAGGAAGGACCTAGAGACACATCCTTGAACTAGAACCTGGGGTGAGAGTTCATTGGGAGGCAGGATCTCTTCTTTCAC TTTGGATTTACACCTTGTCCCTTGGAAAGCTTCTCCACTATGCTAGCAAATATCTTAGGATATTTGATGGAAAGAACTTGAGAATCCCTT CTGGAAAACCCAGCCTTTCAGTGTTAACACCTGCTGCAAGACAGGGATGCTGTTGTTCTGGCAGCCCCCCTTTGCTTTTGCCTGGCCCCA CCTTCTGCTCCCACTCTGCTGGCTTGGGCAAGATGCGTGCCTTGGGCCTTGGGTGCAGGGAGGCAGGCAGGGGCTTGACCTGGCCTCTCT CTGGTGCCATGGCAACATTATGCCCCAAACTTCTTCCCTGGTTGGAGTGAGAGGGGCTGTCCACAGCCCCATCCTGTGGGGATCTCAAGC CGGAGTCCCTGGCCTGGCCTCCTTGACGTAGGTGTTCTCAGCAAGCAGTTTGCATCCCACCGTCTTTCTCACACTTGCCCCCAAGACTTT TGACAGAGCAGACGTAAAACAGGACTCAGAAAACCATTTTTCTCTGTTCCCATATGTAGTAAGTTTTGATTCAGTTGTGCATAAACCATA GTTTTCTGCCCTGCTGTTTGCTTTCAATGGAAGACAGTAAAGGGAAGATGGTGCTCACATCTCTCCATGTGACATCTCATTAGGAATTAA GATGCGATGGATTAGAAATGTAAAACTTCAGAATAAAATTAAATTTCAGGGCTCTATAAGTCCCGTTTTCCCAGGTCCTGTTCCGTTTCT ACGTAGATAACCCAATTTGTTTTGTCTATGAAATAAGCCTCTTTAGTGGGTTGTTTTAGTCTCTCCAACAAAAGAGCAGATTCCTAAAGC CAGGTGCAGCACTGTGAAAAGTTTCTTTCAATATGGCACCAAGACTCTACCATTTATGTCTCTCTCAGCTTACAAACATCAGCGTTTTGT CCTTGTCATAGTGGAAGAAAGACACTTACTTTAAGCTTTGGGGACAAAGGTGACAAACCCCAGGCTTTTATCTTAAAAGTGTCTTTGGCA CTTCTTTTGGCACTGAAATGGTATTTGGGAAGCATTATTTGAATGTACAGTTGTTTGGTTTTGTATGTGCTTATCTTTATCTGAGCTTTC ACTTGTAGACATGGCCTTTTGTTGTGAAGTTGCTCATCATTTAGGAGTGTTTAATTCTAAAAAGCCTTCAGCCTAAGAAAGCTTCATCTG TGGGGACCAGAGACTTGTTGCTCAGGGAGTTAGTGATGGGACTTGGGCATCTGATCTGCAGGTGACAAGTTTAGTTCAACTGAAGTTGTA GGGAATTTAGACAGTTGCACATCATTGCCGTTCTAGGGGCCTTGTAGAAAGATGAAACAGTTGTTTTTCATTTACCAGCACCTCTCAGTT ATAGAGGTAATGGAACATTCGCTTACTTTTCATCATCATTCTTTAAAAAGGGAACATACAAAAATCTAAACTATGGCAATAATTTATTTT TATAATAGTTTACGGTAGGCTTTAATTAAATGGCAAACTCCTCTGGGACCCCTAAGTTATGGCGTGATTAGCCAAATTTGATTTCCAACA GTCATTTATGGCCATAACTATTGCATAGAGTGCAGGATGCCAGCAAAGATGAGGGTGGGGGCAGATACTGGCTCAGTGATTTAACTCACA TTATAGATGACCCCTTCCTCAACAGAAATGCTACTGAGAGAACCAGAGAGGCCTGGGCCAGGCAGGTCTTATTTGAGAGGAGATTATTTG ATAATTGCTTTGGTTAGAAGGACTTTACATTTCCTGATTTCAAGTCCAGCACCAATTTAGAAAGTTCAGAGATGAAACCACCTGTCTTTA CCTGACAGAGTCATAACGGTTTGTGTAAAAATGTGGTCAGGGACCTTTTTTGTTCTTTCTGATTAGTTAATACTGTACATTGTAACCAGG AGGGGCAGTTTTGCCAACCAGCCTCTGCTCATGGTCACCATATGTGTATGACAAGGCCTGAGTGAGTTCCTGCATAAACTGGGTAGTGGG CTCTTTTGACACATTTGCAAGCATGTAAATGAATGAATGACACTACCAGCAACCATCTGTACAGGTCCATTTACTTACATTCATAAGGTT TATGCTATGAAACTTCTTCTCATTGTGATGTCAGTAACAGAGTTAGTGTCTCTGATGGAATAGTGTACCTGTCACCCAAGTTATTTTGTT CCTTTTTGGGTCCTCCAGTATAATCCCCCCCTCATCCCAATTAACTGTAAAATGTTTTACACATCACATTTTTTATACTGTAAACTTGGA >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369510_chr1_116224985_+_9293nt AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCT GAGAAACTCCTTCCTGCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTC CTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTG AAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGC CACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTC ATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCC TCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTC TGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTC TCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGC CTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAG TCTGAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGG GTGTCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAG GAAGCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTT CTGTTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCC CCGTTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGT ATTTGTGTATGTTAATGTCCAGTATCACATCACCCATGAAAGTCGTGGGCAGTTCAGGAGATACCTGCCTTCATCTTTGTTCTTTGTTGC CTTAGGTTCTTCAGAGAAAGATCACAACAAAAAATGTACACTGTCGTTTACAGCTATTAAGTGATTTGATTTTGTTTTTTTCCCAAAGAG AAAACCTACCTGCCCTGTTTCTGATCCCACCCCTCTGCTGGCTTGAAGCAGGTAACCCTTTCCCAGCCCTGCAGCTGCCCACCTGGCCTC CATGCCATCCTGCCCCCACCTGGCTGGCAGCCCTGGCTCTCCATGTGTGCCCTCCGGCTCTGTGTGAAGCCTCAAGTCAGTCCCAGCATT GTTTCCATAGGGAAGTGTGGGGTGCCCAGCAGGTAAAGCACAGGGAGAGAGGGCAGTGGGAATGCCACCTTTAGGCTGCAGCAGGAGCCC CACACTGCCCAGTTTTCCTCCCCACTGTTCTACACCAACCAGGGGAGACTAACACTGTGACTCTGGGATTGGCAGGTGCAACTTGGAGCC ACTTAATTTCCTGGGGACGTAAGTTCTTCCCAAGCTTAGAGCAAGCTGCCCTGCCAAAGGAGACCAAACCATGCCAACCACGCTGGCAAC TGCTGCTGTCCAGTCCCTGTGTTTTCTGACCACCGTCACTGTGCAACTCATCGCCTCTGCCACTTAGGACCAGGAAAGAGGCTGGTTTTG CTCCCACTCTTAGTTGCTGATAAAGTGGGGAGAAGGAAAATGGACACTCTACAGAGTTTGGGGAAGGGAGAGTAGGGAGCCCATCTTGTC CAGAAAGATTCATCTGTGGTCTGTCTGTTAAACACAGCTGATTTCAGTGGGCTTTCCCCTGGCCCTGGGGGAGCAGACACTGACTGGGTT GTGGGCAGAGGAGCCATCCTGGCGGAGCCCTGCTGCAGGGGAGCTCCTTCAGGAGCCCCATCCGGACCTCTTGCACTGGGCTGCCTTTGC CTCCATTTGCCTTCCTGTATCTGCAACAAACCTTTTAAAAGTGTTCACTCTTGCTTTTTCCAGTATTTCGGTAATCAGCCATCTTGCTGT AGTACAGGATGACATTGTCGAATGCTCTTTGTATGTGTGCACACCCCCTTACTCCCTTACTGCTTCATACACTCCACAAGTGGTACAGTA TTTTGTGTCATTGTAAAAATCAAAATTGGCTTTGGATCTTTGTAATACACCTGTACCTGAAAAAGTAAACAACATTCTTCAATTACTAGC CTTCAGCTTGAAAAGACATGCTGGAGAAGAAGGAAGGGGGAACCCATAGGTGTGGCGTGGAGCCAAGATGTACTATTCAACTATGTGTTT CTGTTTATAAAAAACACATACCATGGAACCATGGTGCTTTTGTTCTTAGTTTTTGCCGTTAGATCCCTTCAAACTGGAAGTTCCTTACAA TATCTTTCTCAGGAAATATTTTGGGAAATGGGGTAAGAGATGGCAAGTGTGAGACGGGCTGTGTCAGAGGTTGCTACGTCATGGATACAG TGCAGTTCCAAGTGCCATAAGTGTATGTACATATAGTTAATAATGACACTGTTCATCACCATTCTAAAATACTGTTCTTCCAACCCTATC TTCAATGACCAGTCCAGAAGGGGTTAAGCTGGATTCATTTGCTCTGGCATGTGCATTCCCAGCAGGGTGAAGAAAGGTTTAAATTAAAGA ATTTATTTTCTCTCTCCCCCTTCCTCTTTCTCCCAGTCTTTGCATAGGAGAATGTTAGACATTCAGAAATTACTGTTTCTGTTTTAAATT GAGTATTGATTTTTTTATATTGACTTTGTATTGAGTTCTTTTTGAAAGAATAACAAAATAAAATGCAGGATCTTTGTAAAGCCTTTGCAC TTTCAACCTCTTTATAGCTTGAGTTACTTTTGCAGTGGGAACAATGTAAATGACATTTAAAAGATTTAAGGTTTCAGAAAGCTGCATCCC ACAATTGAACACAATGCATTTTTATTTCAATTCTTGGAACTGGTAGGCTATTCTTTTTAAAAGGGGGTAAACTTCGCCCTAAGGCTGGTA GAATGTATGTTCACATTATAGTAGACAGGATTTCATTTGCCTTATATGTTTATAGATTTTTTATAATTTTCATCCTACGTTATTAAAATT AGAGCATTGAGTGTTAAAGAACTTAATGAGGAGTCTATATCTGAGATTGCTCTCTTCCCTGGTGATGTTTTAACTGGTAGATAATTTGTT CTTAAATATGTACTTTTGAAGATAGGACAGTTTTTATAGTCCATGAACTGAATGTTAAAAAGTTCTGTATGCATTCTCAGAGAGGATTTT AAAGCTATATAGTTCATCCATCCTTTGCATTATCAAAATGTTAAGTCAAATCTGTAATACTTTGGCTAAAATTCATAAAGTAAGCCCTAG AGAAAATACTTGACCACCAAATTTTTGCCCAACTATCATCACCTCCCTTCCCCCGCCTCTGTTCTTGCCTTTTGACATCTACATGGAAGA CAAGTTCTTTACAGCAAATGGTAAGAGGCAGGTGACCTGGTGTGTTTGCTGTGTTGTAGTTCATTGCCTGGGGCTTGGGACTCCTTTTTT AATGGAGAGACTAGCTGTGCAGGTGTGTGTTGGATAGGGATAAAGTGCTCACCCCTGCCCTCTCTACAGTAGTTGGTGGTAGATTTCTCT CTCATTTTGCCTCATAATCACTTTCGAGTGCATGTATTTACCTAAGGGCTGTAGCTCTGTGGGATGCTACCAGCATATTGGACTGACAGA AATTGATTACCTTGCCACTCCAACCTACGTACTGAGTGAGTGCTCCAGCCACTCAGTGAAACCAACAAAAGTGAGTCCTTGGTTTACCTT CCAATCTGGGTCCTGCTGTGTAAGTATCCCTAAGTGGGGATGCATATTTGTTTGTGCGTTTTTATTTCCATATATGTGAGCATTTCTCTG AGTGTATTACCAGACGGATAGCACATTTATATGTCAGACATCTTAACATCTGTGTTATCTGTAGCAGGTGTGTAGCTCAGCAGATACGTG TCATTGTGTATATAGCTGAGTGTGTGAGGGTGTCTGTGTTTCTGCAGTCCCCTGTGTTTGAGAGATGACTTAATAACCCTGTGTTTTGAG AGGTCGCTCTAAACCAGTGACTTTTCCCTCCCCTGCTTTATTCCTTTCCCTCACTGACACTGGCTTCTCCCGCTAGAGTAAATGGCTTTA GCACAGCACTGTCTTCTGGGGAGCCTGCTGTCCTGCAGGCAAGTCCATTAAACTCTTTCTTGCTTTAGGACTCTGAAAACAGCAAGAAAC AAACAAACAAAGGTCAAGCTCTAAGAAAATTACTGCTCAAACTTCACTACCCTGGAAGCCTTACTAGATATTTCTTAAGGTAACTTAAAA ATTGGGCTTTATTTTTAAAAAGTGATAGGTTACTTACAGTAGCACAGAAATGTTAGCATATTTATTTAAATAGTCCTGCAGCAGAGACCC TGCGATTGTAAAGTGATTTAAGTATTTCTGGGTAGTGTTTGTGATTTACGGATTTGTTACTGAAAAACAAAAAAATCACTACTGTGAATT TACTACTATGTAACCTTGTGGTCGTATTTCATTATAAATAAAATAAGAATTGCTCTTCTGCCCACCGTTCTTGATTGGTATTCAGTGCAG TAGCGAAATGAGATAGTTTAGACACTGTTGAAATAACTGCATTGAGCTTTAACCAAGTGTATGCTCAGAAAATTCAGTTTTGGATCACAT TTTGACAAAACATGTTTTGGTCAAAGAAAGGAAAGGCTACTAACACATTTATCAGGTAATGTATGTCACAGTCCGTGTTCCACCCAGCCT TGTTATCCCCACATTCTTTCAAGATAGGAGTCATCTTGGTTTTTCGGGTGAAAAACGGAAGGTCAGAGAGGAAGGGGCTTGTCCAAGGTC TCATGTCTGGTTAACAGAATTTCAAACTAGATGTTTGATTCTAACCCCTCAGTCCACTGTACCTTGAAGTATGGTCTAAATGATTCGGCA CTTCTGGATGTTGAGGAAGGACCTAGAGACACATCCTTGAACTAGAACCTGGGGTGAGAGTTCATTGGGAGGCAGGATCTCTTCTTTCAC TTTGGATTTACACCTTGTCCCTTGGAAAGCTTCTCCACTATGCTAGCAAATATCTTAGGATATTTGATGGAAAGAACTTGAGAATCCCTT CTGGAAAACCCAGCCTTTCAGTGTTAACACCTGCTGCAAGACAGGGATGCTGTTGTTCTGGCAGCCCCCCTTTGCTTTTGCCTGGCCCCA CCTTCTGCTCCCACTCTGCTGGCTTGGGCAAGATGCGTGCCTTGGGCCTTGGGTGCAGGGAGGCAGGCAGGGGCTTGACCTGGCCTCTCT CTGGTGCCATGGCAACATTATGCCCCAAACTTCTTCCCTGGTTGGAGTGAGAGGGGCTGTCCACAGCCCCATCCTGTGGGGATCTCAAGC CGGAGTCCCTGGCCTGGCCTCCTTGACGTAGGTGTTCTCAGCAAGCAGTTTGCATCCCACCGTCTTTCTCACACTTGCCCCCAAGACTTT TGACAGAGCAGACGTAAAACAGGACTCAGAAAACCATTTTTCTCTGTTCCCATATGTAGTAAGTTTTGATTCAGTTGTGCATAAACCATA GTTTTCTGCCCTGCTGTTTGCTTTCAATGGAAGACAGTAAAGGGAAGATGGTGCTCACATCTCTCCATGTGACATCTCATTAGGAATTAA GATGCGATGGATTAGAAATGTAAAACTTCAGAATAAAATTAAATTTCAGGGCTCTATAAGTCCCGTTTTCCCAGGTCCTGTTCCGTTTCT ACGTAGATAACCCAATTTGTTTTGTCTATGAAATAAGCCTCTTTAGTGGGTTGTTTTAGTCTCTCCAACAAAAGAGCAGATTCCTAAAGC CAGGTGCAGCACTGTGAAAAGTTTCTTTCAATATGGCACCAAGACTCTACCATTTATGTCTCTCTCAGCTTACAAACATCAGCGTTTTGT CCTTGTCATAGTGGAAGAAAGACACTTACTTTAAGCTTTGGGGACAAAGGTGACAAACCCCAGGCTTTTATCTTAAAAGTGTCTTTGGCA CTTCTTTTGGCACTGAAATGGTATTTGGGAAGCATTATTTGAATGTACAGTTGTTTGGTTTTGTATGTGCTTATCTTTATCTGAGCTTTC ACTTGTAGACATGGCCTTTTGTTGTGAAGTTGCTCATCATTTAGGAGTGTTTAATTCTAAAAAGCCTTCAGCCTAAGAAAGCTTCATCTG TGGGGACCAGAGACTTGTTGCTCAGGGAGTTAGTGATGGGACTTGGGCATCTGATCTGCAGGTGACAAGTTTAGTTCAACTGAAGTTGTA GGGAATTTAGACAGTTGCACATCATTGCCGTTCTAGGGGCCTTGTAGAAAGATGAAACAGTTGTTTTTCATTTACCAGCACCTCTCAGTT ATAGAGGTAATGGAACATTCGCTTACTTTTCATCATCATTCTTTAAAAAGGGAACATACAAAAATCTAAACTATGGCAATAATTTATTTT TATAATAGTTTACGGTAGGCTTTAATTAAATGGCAAACTCCTCTGGGACCCCTAAGTTATGGCGTGATTAGCCAAATTTGATTTCCAACA GTCATTTATGGCCATAACTATTGCATAGAGTGCAGGATGCCAGCAAAGATGAGGGTGGGGGCAGATACTGGCTCAGTGATTTAACTCACA TTATAGATGACCCCTTCCTCAACAGAAATGCTACTGAGAGAACCAGAGAGGCCTGGGCCAGGCAGGTCTTATTTGAGAGGAGATTATTTG ATAATTGCTTTGGTTAGAAGGACTTTACATTTCCTGATTTCAAGTCCAGCACCAATTTAGAAAGTTCAGAGATGAAACCACCTGTCTTTA CCTGACAGAGTCATAACGGTTTGTGTAAAAATGTGGTCAGGGACCTTTTTTGTTCTTTCTGATTAGTTAATACTGTACATTGTAACCAGG AGGGGCAGTTTTGCCAACCAGCCTCTGCTCATGGTCACCATATGTGTATGACAAGGCCTGAGTGAGTTCCTGCATAAACTGGGTAGTGGG CTCTTTTGACACATTTGCAAGCATGTAAATGAATGAATGACACTACCAGCAACCATCTGTACAGGTCCATTTACTTACATTCATAAGGTT TATGCTATGAAACTTCTTCTCATTGTGATGTCAGTAACAGAGTTAGTGTCTCTGATGGAATAGTGTACCTGTCACCCAAGTTATTTTGTT CCTTTTTGGGTCCTCCAGTATAATCCCCCCCTCATCCCAATTAACTGTAAAATGTTTTACACATCACATTTTTTATACTGTAAACTTGGA >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000310260_chr1_116224985_+_2923nt AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCT GAGAAACTCCTTCCTGCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTC CTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTG AAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGC CACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTC ATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCC TCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTC TGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTC TCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGC CTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAG TCTGAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGG GTGTCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAG GAAGCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTT CTGTTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCC CCGTTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGT >In-frame_MAN1A2_ENST00000356554_chr1_117984947_+_VANGL1_ENST00000369509_chr1_116224985_+_2923nt AGACCCGTGCGGTAGCAACAGCGGCGGCGGCCGCGGCGGCTGGCCGGACTCAGGTGTTTCGGACGCTATTGCCCTTCGCGCCAGCCGTCG AGTGGGCAGCAGCGGGACTCAGCCGGGCGCCAGGTTCCTGCCAGGCAGCGCCGGGAAGCGCGGGCGGCCGAGAACTCCTTCCTGCTACTT CGCCCAGCGCCGCTGCTTCGGCTTCCCAGCGAAGTGGGAGACCTTCCTCCCTGTTTGCAGACGTCCGTGGGAGACCCTTATTTTTTCCAC CGCTAAGGTTAAGAGATTCTGGAATAGAAGCGTCGAAGGAGATCAAGTGAACCTTCTACAACTCCTCGGATGTCGCCAGTCTCCCTTTCG GGGCGGAAGACTACGTTTGAGCATCTCACTGAGGTGCAGGAATGGAAGAACCCACCTTGCAGCTTTTCTGCAGTGTGGCTTGCCTGATCT ACCCCTAGGAATGAAGAGGAGGCTTGTAATAATCCGATGAAGTACAGATGTTGAAGAGGATATCGCAGGACCTAAACTTGTGATCGTTTG GGGGAGGTCACACACGTTTCTGAGTGGGAATGGATGGGCGTGAATGACGTGCCCTCTTAAAAAGCACAACAGTCCTTTAAGAGGAGCAAA ATTGAGTTTTCCCATTTTGGCCAAGATTTTGAAGACAGTTCAATGTATTCTACATTTGACATAAGATGAGAACTTTCTAAAGTATTCTCT CCAAGAGCGTAAACGATGACTACCCCAGCCCTGCTGCCCCTCTCTGGACGTAGGATACCACCTCTGAACCTGGGGCCGCCTTCCTTCCCA CATCACAGGGCTACCTTGAGACTTTCTGAGAAGTTTATTCTTCTCCTTATTCTTAGTGCCTTCATCACTCTGTGTTTTGGGGCATTCTTT TTCCTTCCAGACTCTTCAAAACACAAACGCTTTGATTTGGGTTTAGAAGATGTGTTAATTCCACATGTAGATGCCGGTAAAGGGGCTAAA AACCCCGGAGTCTTCCTGATCCATGGACCCGATGAACATAGACACAGGGAAGAGGAAGAACGTCTGAGAAATAAAATTCGAGCTGATCAT GAGAAGGCCTTGGAAGAAGCAAAAGAAAAATTAAGAAAGTCAAGAGAGGAAATTCGAGCAGAAATTCAGACAGAGAAAAATAAGGTAGTC CAAGAAATGAAGATAAAAGAGAACAAGCCACTGCCACCAGTCCCTATTCCCAACCTTGTAGGAATACGTGGTGGAGACCCAGAAGATAAT GACATAAGAGAGAAAAGGGAAAAAATTAAAGAGATGATGAAACATGCTTGGGATAACTATAGGACATATGGGTGGGGACATAATGAACTC AGACCTATTGCAAGGAAAGGACACTCCCCTAACATATTTGGAAGTTCACAAATGGGTGCTACCATAGTAGATGCTTTGGATACCCTTTAT ATCATGGGACTTCATGATGAATTCCTAGATGGGCAAAGATGGATTGAAGACAACCTTGATTTCAGTGTGAATTCAGAGGTGTCTGTGTTT GAAGTCAACATTCGATTTATTGGAGGCCTACTTGCAGCATATTACCTATCAGGAGAGGAGATATTCAAGATTAAAGCAGTGCAATTGGCT GAGAAACTCCTTCCTGCCTTTAACACACCTACTGGGATTCCTTGGGCAATGGTGAATTTGAAAAGTATCCAGCGAGCAGCATTGGTGGTC CTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTG AAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGC CACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTC ATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCC TCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTC TGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTC TCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGC CTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAG TCTGAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGG GTGTCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAG GAAGCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTT CTGTTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCC CCGTTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGT |
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FusionGenePPI for MAN1A2_VANGL1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MAN1A2 | SMAD9, CLDND1, CD1B, SCARA3, CLU, C5AR2, CD1E, SCGB2A2, TMEM30B, IL13RA2, ADAM32, PMEL, B4GAT1, TLR5, TRHDE, PTPRO | VANGL1 | KBTBD7, RAPGEF5, NT5C3A, GMFG, SMYD3, THAP2, SRPK1, FBXW11, CCDC8, SPRY2, ZRANB2, LUC7L, EPB41L3, RASSF9, RASSF10, TCTN3, EVC2, TMEM17, TMEM216, NAF1, VANGL2, PTPN3, GPR156, CD44, DVL3, SDC2, PNN, TNFRSF1A, MANSC1, SDC1, PRICKLE3, NXF2, EPB41L5, CD83, JPH4, FGF8, ZC3H18, TRIM25, RNF41, ERBB4 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MAN1A2_VANGL1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MAN1A2_VANGL1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | VANGL1 | C0027794 | Neural Tube Defects | 2 | CTD_human |
| Tgene | VANGL1 | C1838568 | Sacral defect and anterior sacral meningocele | 1 | CTD_human;UNIPROT |
| Tgene | VANGL1 | C3891448 | NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO | 1 | UNIPROT |
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