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Fusion gene ID: 20570 |
FusionGeneSummary for MAGED2_SCAMP4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAGED2_SCAMP4 | Fusion gene ID: 20570 | Hgene | Tgene | Gene symbol | MAGED2 | SCAMP4 | Gene ID | 10916 | 113178 |
| Gene name | MAGE family member D2 | secretory carrier membrane protein 4 | |
| Synonyms | 11B6|BARTS5|BCG-1|BCG1|HCA10|MAGE-D2 | SCAMP-4 | |
| Cytomap | Xp11.21 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | melanoma-associated antigen D2MAGE-D2 antigenbreast cancer-associated gene 1 proteinhepatocellular carcinoma-associated protein JCL-1melanoma antigen family D, 2melanoma antigen family D2 | secretory carrier-associated membrane protein 4 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9UNF1 | Q969E2 | |
| Ensembl transtripts involved in fusion gene | ENST00000375068, ENST00000375053, ENST00000347546, ENST00000375062, ENST00000218439, ENST00000375058, ENST00000375060, ENST00000396224, ENST00000497484, | ENST00000316097, ENST00000414057, ENST00000409472, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 2 X 2 X 2=8 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: MAGED2 [Title/Abstract] AND SCAMP4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-HC-7745-01A | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000375068 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375068 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375068 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3CDS | ENST00000375053 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000375053 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000375053 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| In-frame | ENST00000347546 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000347546 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000347546 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3CDS | ENST00000375062 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000375062 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000375062 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3CDS | ENST00000218439 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000218439 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000218439 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| Frame-shift | ENST00000375058 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375058 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375058 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| Frame-shift | ENST00000375060 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375060 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| 5CDS-3UTR | ENST00000375060 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3CDS | ENST00000396224 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000396224 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000396224 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3CDS | ENST00000497484 | ENST00000316097 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000497484 | ENST00000414057 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
| intron-3UTR | ENST00000497484 | ENST00000409472 | MAGED2 | chrX | 54842445 | + | SCAMP4 | chr19 | 1917693 | + |
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FusionProtFeatures for MAGED2_SCAMP4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAGED2 | SCAMP4 |
| Regulates the expression, localization to the plasmamembrane and function of the sodium chloride cotransportersSLC12A1 and SLC12A3, two key components of salt reabsorption inthe distal renal tubule. {ECO:0000269|PubMed:27120771}. | Probably involved in membrane protein trafficking.{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for MAGED2_SCAMP4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_MAGED2_ENST00000347546_chrX_54842445_+_SCAMP4_ENST00000316097_chr19_1917693_+_925aa MSDTSESGAGLTRFQAEASEKDSSSMMQTLLTVTQNVEVPETPKASKATEVSKTPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKK QNADPQAVTMPATETKKVSHVADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTRPKVKAKKARKVKHLDGEEDGSSDQSQASG TTGGRRVSKALMASMARRASRGPIAFWARRASRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEAPPPRDVALLQGRANDLVK YLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEKVFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSI IFMNGNRSSEAVIWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYETSKMKVLKFACKVQKKDP KEWAAQYREAMEADLKAAAEAAAEAKARAEIRARMGIGLGSENAAGPCNWDEADIGPWAKARIQAGAEAKAKAQESGSASTGASTSTNNS ASASASTSGGFSAGASLTATLTFGLFAGLGGAGASTSGSSGACGFSYKXDFRYLPWFQWGHLGLMGLGXGAGXFXEGPSWRMMWRVCQDT AFGILFLSVCWMSIDPFIFSYLCFQILLILPVFLFKPGCILRNLLNTALXAATINQLKLTLCIKSICQKENNFPPLPKFIPVKPCFYQNF SDEIPVEHQVLVKRIYRLWMFYCATLGVNLIACLAWWIGGGSGTNFGLAFVWLLLFTPCGYVCWFRPVYKAFRADSSFNFMAFFFIFGAQ FVLTVIQAIGFSGWGACGWLSAIGFFQYSPGAAVVMLLPAIMFSVSAAMMAIAIMKVHRIYRGAGGSFQKAQTEWNTGTWRNPPSREAQY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_MAGED2_ENST00000347546_chrX_54842445_+_SCAMP4_ENST00000316097_chr19_1917693_+_2775nt ATGTCTGACACAAGCGAGAGTGGTGCAGGTCTAACTCGCTTCCAGGCTGAAGCTTCAGAAAAGGACAGTAGCTCGATGATGCAGACTCTG TTGACAGTGACCCAGAATGTGGAGGTCCCAGAGACACCGAAGGCCTCAAAGGCCACAGAGGTCTCAAAGACCCCAGAGGCTCGGGAGGCA CCTGCCACCCAGGCCTCATCTACTACTCAGCTGACTGATACCCAGGTTCTGGCAGCTGAAAACAAGAGTCTAGCAGCTGACACCAAGAAA CAGAATGCTGACCCGCAGGCTGTGACAATGCCTGCCACTGAGACCAAAAAGGTCAGCCATGTGGCTGATACAAAGGTCAATACAAAGGCT CAGGAGACTGAGGCTGCACCCTCTCAGGCCCCAGCAGATGAACCTGAGCCTGAGAGTGCAGCTGCCCAGTCTCAGGAGAATCAGGATACT CGGCCCAAGGTCAAAGCCAAGAAAGCCCGAAAGGTGAAGCATCTGGATGGGGAAGAGGATGGCAGCAGTGATCAGAGTCAGGCTTCTGGA ACCACAGGTGGCCGAAGGGTCTCAAAGGCCCTAATGGCCTCAATGGCCCGCAGGGCTTCAAGGGGTCCCATAGCCTTTTGGGCCCGCAGG GCATCAAGGACTCGGTTGGCTGCTTGGGCCCGGAGAGCCTTGCTCTCCCTGAGATCACCTAAAGCCCGTAGGGGCAAGGCTCGCCGTAGA GCTGCCAAGCTCCAGTCATCCCAAGAGCCTGAAGCACCACCACCTCGGGATGTGGCCCTTTTGCAAGGGAGGGCAAATGATTTGGTGAAG TACCTTTTGGCTAAAGACCAGACGAAGATTCCCATCAAGCGCTCGGACATGCTGAAGGACATCATCAAAGAATACACTGATGTGTACCCC GAAATCATTGAACGAGCAGGCTATTCCTTGGAGAAGGTATTTGGGATTCAATTGAAGGAAATTGATAAGAATGACCACTTGTACATTCTT CTCAGCACCTTAGAGCCCACTGATGCAGGCATACTGGGAACGACTAAGGACTCACCCAAGCTGGGTCTGCTCATGGTGCTTCTTAGCATC ATCTTCATGAATGGAAATCGGTCCAGTGAGGCTGTCATCTGGGAGGTGCTGCGCAAGTTGGGGCTGCGCCCTGGGATACATCATTCACTC TTTGGGGACGTGAAGAAGCTCATCACTGATGAGTTTGTGAAGCAGAAGTACCTGGACTATGCCAGAGTCCCCAATAGCAATCCCCCTGAA TATGAGTTCTTCTGGGGCCTGCGCTCTTACTATGAGACCAGCAAGATGAAAGTCCTCAAGTTTGCCTGCAAGGTACAAAAGAAGGATCCC AAGGAATGGGCAGCTCAGTACCGAGAGGCGATGGAAGCGGATTTGAAGGCTGCAGCTGAGGCTGCAGCTGAAGCCAAGGCTAGGGCCGAG ATTAGAGCTCGAATGGGCATTGGGCTCGGCTCGGAGAATGCTGCCGGGCCCTGCAACTGGGACGAAGCTGATATCGGACCCTGGGCCAAA GCCCGGATCCAGGCGGGAGCAGAAGCTAAAGCCAAAGCCCAAGAGAGTGGCAGTGCCAGCACTGGTGCCAGTACCAGTACCAATAACAGT GCCAGTGCCAGTGCCAGCACCAGTGGTGGCTTCAGTGCTGGTGCCAGCCTGACCGCCACTCTCACATTTGGGCTCTTCGCTGGCCTTGGT GGAGCTGGTGCCAGCACCAGTGGCAGCTCTGGTGCCTGTGGTTTCTCCTACAAGTGAGATTTTAGGTATCTGCCTTGGTTTCAGTGGGGA CATCTGGGGCTTATGGGGCTGGGATGAGGAGCTGGATGATTCTAGGAAGGCCCAAGTTGGAGAATGATGTGGAGAGTGTGCCAAGACACT GCTTTTGGCATTTTATTCCTTTCTGTTTGCTGGATGTCAATTGACCCTTTTATTTTCTCTTACTTGTGTTTTCAGATATTGTTAATCCTG CCAGTCTTTCTCTTCAAGCCAGGGTGCATCCTCAGAAACCTACTCAACACAGCACTCTAGGCAGCCACTATCAATCAATTGAAGTTGACA CTCTGCATTAAATCTATTTGCCAAAAGGAGAACAACTTCCCGCCACTGCCCAAGTTCATCCCTGTGAAGCCCTGCTTCTACCAGAACTTC TCCGACGAGATCCCAGTGGAGCACCAGGTCCTGGTGAAGAGGATCTACCGGCTGTGGATGTTTTACTGCGCCACCCTCGGCGTCAACCTC ATTGCCTGCCTGGCCTGGTGGATCGGCGGAGGCTCGGGGACCAACTTCGGCCTGGCCTTCGTGTGGCTGCTCCTGTTCACGCCTTGCGGC TACGTGTGCTGGTTCCGGCCTGTCTACAAGGCCTTCCGAGCCGACAGCTCCTTTAATTTCATGGCGTTTTTCTTCATCTTCGGAGCCCAG TTTGTCCTGACCGTCATCCAGGCGATTGGCTTCTCCGGCTGGGGCGCGTGCGGCTGGCTGTCGGCAATTGGATTCTTCCAGTACAGCCCG GGCGCTGCCGTGGTCATGCTGCTTCCAGCCATCATGTTCTCCGTGTCGGCTGCCATGATGGCCATCGCGATCATGAAGGTGCACAGGATC TACCGAGGGGCTGGCGGAAGCTTCCAGAAGGCACAGACGGAGTGGAACACGGGCACTTGGCGGAACCCACCGTCGAGGGAGGCCCAGTAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_MAGED2_ENST00000347546_chrX_54842445_+_SCAMP4_ENST00000316097_chr19_1917693_+_4593nt GACTTCGAGAGGGACTTAGAGAAGGCAGACGCATCCCGAACTCGCTGGAGGACAAGGCTCAGCTCTTGCCAGGCCAAATTGAGACATGTC TGACACAAGCGAGAGTGGTGCAGGTCTAACTCGCTTCCAGGCTGAAGCTTCAGAAAAGGACAGTAGCTCGATGATGCAGACTCTGTTGAC AGTGACCCAGAATGTGGAGGTCCCAGAGACACCGAAGGCCTCAAAGGCCACAGAGGTCTCAAAGACCCCAGAGGCTCGGGAGGCACCTGC CACCCAGGCCTCATCTACTACTCAGCTGACTGATACCCAGGTTCTGGCAGCTGAAAACAAGAGTCTAGCAGCTGACACCAAGAAACAGAA TGCTGACCCGCAGGCTGTGACAATGCCTGCCACTGAGACCAAAAAGGTCAGCCATGTGGCTGATACAAAGGTCAATACAAAGGCTCAGGA GACTGAGGCTGCACCCTCTCAGGCCCCAGCAGATGAACCTGAGCCTGAGAGTGCAGCTGCCCAGTCTCAGGAGAATCAGGATACTCGGCC CAAGGTCAAAGCCAAGAAAGCCCGAAAGGTGAAGCATCTGGATGGGGAAGAGGATGGCAGCAGTGATCAGAGTCAGGCTTCTGGAACCAC AGGTGGCCGAAGGGTCTCAAAGGCCCTAATGGCCTCAATGGCCCGCAGGGCTTCAAGGGGTCCCATAGCCTTTTGGGCCCGCAGGGCATC AAGGACTCGGTTGGCTGCTTGGGCCCGGAGAGCCTTGCTCTCCCTGAGATCACCTAAAGCCCGTAGGGGCAAGGCTCGCCGTAGAGCTGC CAAGCTCCAGTCATCCCAAGAGCCTGAAGCACCACCACCTCGGGATGTGGCCCTTTTGCAAGGGAGGGCAAATGATTTGGTGAAGTACCT TTTGGCTAAAGACCAGACGAAGATTCCCATCAAGCGCTCGGACATGCTGAAGGACATCATCAAAGAATACACTGATGTGTACCCCGAAAT CATTGAACGAGCAGGCTATTCCTTGGAGAAGGTATTTGGGATTCAATTGAAGGAAATTGATAAGAATGACCACTTGTACATTCTTCTCAG CACCTTAGAGCCCACTGATGCAGGCATACTGGGAACGACTAAGGACTCACCCAAGCTGGGTCTGCTCATGGTGCTTCTTAGCATCATCTT CATGAATGGAAATCGGTCCAGTGAGGCTGTCATCTGGGAGGTGCTGCGCAAGTTGGGGCTGCGCCCTGGGATACATCATTCACTCTTTGG GGACGTGAAGAAGCTCATCACTGATGAGTTTGTGAAGCAGAAGTACCTGGACTATGCCAGAGTCCCCAATAGCAATCCCCCTGAATATGA GTTCTTCTGGGGCCTGCGCTCTTACTATGAGACCAGCAAGATGAAAGTCCTCAAGTTTGCCTGCAAGGTACAAAAGAAGGATCCCAAGGA ATGGGCAGCTCAGTACCGAGAGGCGATGGAAGCGGATTTGAAGGCTGCAGCTGAGGCTGCAGCTGAAGCCAAGGCTAGGGCCGAGATTAG AGCTCGAATGGGCATTGGGCTCGGCTCGGAGAATGCTGCCGGGCCCTGCAACTGGGACGAAGCTGATATCGGACCCTGGGCCAAAGCCCG GATCCAGGCGGGAGCAGAAGCTAAAGCCAAAGCCCAAGAGAGTGGCAGTGCCAGCACTGGTGCCAGTACCAGTACCAATAACAGTGCCAG TGCCAGTGCCAGCACCAGTGGTGGCTTCAGTGCTGGTGCCAGCCTGACCGCCACTCTCACATTTGGGCTCTTCGCTGGCCTTGGTGGAGC TGGTGCCAGCACCAGTGGCAGCTCTGGTGCCTGTGGTTTCTCCTACAAGTGAGATTTTAGGTATCTGCCTTGGTTTCAGTGGGGACATCT GGGGCTTATGGGGCTGGGATGAGGAGCTGGATGATTCTAGGAAGGCCCAAGTTGGAGAATGATGTGGAGAGTGTGCCAAGACACTGCTTT TGGCATTTTATTCCTTTCTGTTTGCTGGATGTCAATTGACCCTTTTATTTTCTCTTACTTGTGTTTTCAGATATTGTTAATCCTGCCAGT CTTTCTCTTCAAGCCAGGGTGCATCCTCAGAAACCTACTCAACACAGCACTCTAGGCAGCCACTATCAATCAATTGAAGTTGACACTCTG CATTAAATCTATTTGCCAAAAGGAGAACAACTTCCCGCCACTGCCCAAGTTCATCCCTGTGAAGCCCTGCTTCTACCAGAACTTCTCCGA CGAGATCCCAGTGGAGCACCAGGTCCTGGTGAAGAGGATCTACCGGCTGTGGATGTTTTACTGCGCCACCCTCGGCGTCAACCTCATTGC CTGCCTGGCCTGGTGGATCGGCGGAGGCTCGGGGACCAACTTCGGCCTGGCCTTCGTGTGGCTGCTCCTGTTCACGCCTTGCGGCTACGT GTGCTGGTTCCGGCCTGTCTACAAGGCCTTCCGAGCCGACAGCTCCTTTAATTTCATGGCGTTTTTCTTCATCTTCGGAGCCCAGTTTGT CCTGACCGTCATCCAGGCGATTGGCTTCTCCGGCTGGGGCGCGTGCGGCTGGCTGTCGGCAATTGGATTCTTCCAGTACAGCCCGGGCGC TGCCGTGGTCATGCTGCTTCCAGCCATCATGTTCTCCGTGTCGGCTGCCATGATGGCCATCGCGATCATGAAGGTGCACAGGATCTACCG AGGGGCTGGCGGAAGCTTCCAGAAGGCACAGACGGAGTGGAACACGGGCACTTGGCGGAACCCACCGTCGAGGGAGGCCCAGTACAACAA CTTCTCAGGCAACAGCCTGCCCGAGTACCCCACTGTGCCCAGCTACCCGGGCAGTGGCCAGTGGCCTTAGAGGGAGCCTGCCCTGCCCCC ACCGCCCACCACCTCCTCCCCTTCATTCCTGCTGCTACCCCTGGTCCCGAGGGCTGGGAGTACCTGGGGCCCCATCCCCCCAGCTGGGAT GGTGGAAGCCGGTGGTGGCCACGGACCGCCCCCCTCCTGCCAGGGCCACAGAACCCGTGTTCATCTCATCCGAGAGCGGAGTTCCTCACA AGCACTCCCCAGCAGCCCTTGGCCTCTGCCGTCCACAGGACGCCCTCTTGCTCCCGGAAACGTGTGGTCACCCGCCGTCCACTGCACGGC TGGTACGGCCTTGTCTTCAGGTCTCGAGGCCTGACTCCGGGGGACAGGTGGCAGCAGGTCGGCCGCCCTCCCGTCCTCCCAGAGCTGCTG GCGCTGAGGTCAGAGCGGGTCTGATGGGGAGCTCCGTCTCACCGGCCACCCGCCGTCACCATGGCAGATGCCCTTGGCCGGAACTAATAA GAGGCGTCGGGGCCAGCTTCCGGTCCCCTGCAGTGATAGAGGGCTTGGTGCCTAGCTGAGTCCTCGCTGTCCCCGCCATCCCCTGATCTG TGCGGCTCCAGCCTCGCCCCCTCCCCACGTGCACCATACCTGGGGAGTTCCTGGTCCAGGGTATCCTGGGGCCACCCTCCCTGCCTCCAA AACAGGGATCCCTGGCAGGCTGTCTTTCCACGCCCCTGAGTTCAGAGTCGGGGACCCAGGCCAGGTCGGGAGCACAGCCGCTCCCCAAAC CCAGCAAACCGGCAGAGAGCCGGTTTCCCAGCAGCCGGAGCCCTGCAGGAGAGGCCTTTGTGTTTTGTTTTGTTTTGTTTTTTCTCTTTT GAGACAAGAGTTTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCAACCTCTGCCTCCCGTGTTCAAGCAGTT CTCCTGCCTCAGCCTCCCAAATAGCTGGGATTACAGTTGCCTGCCACCACGCCCAGCTAATTTTTATATTTTTAGTACAGATGGGGTTTC ACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATAATAGGTGTCAGCC ACCGCGCCCAGCCTGGAGTGGCCTTTTATGAGAGGGGACCCGTCAAATCTGTGCCTTATGGAGGGGTCCGGCAGCGGCCACAATTGTCTT GTCCCCTCACCCCCCAACTCCCCCTGGAACACCTCTCCCAGGCAAGACATTTTCACAGCACCATTCACAACGGTTGGGCCAAAAAGAAAC TTTTCCTTCATCATTTCCTGCACTCGCTGACCACAACTTTGGACACCCCAGGCTGCCACCCCTCCCCACCCGTTCACCCCCAGGATGCTG TTGCTGTAGGACGCCTGCTGCCCTGGAGCCCTCCCCAGGATGTGAGCCAGTCCCCTCGCTGGTACGGAATGCCGCTGGGTGCCCGGAGGC GGCCATGGTGTCTCGATGGACGGCAGCCAGGATGGAGCACCCATGGGTCTCACGGCCATGCTTCAGGGTCTTCAGGTCCTGCCCCCGGCC AGTCTGCCAAGAGGCACCCCCTTCCCCAGCCTCTCGCCTGCACTGATGCAGACAAAATCTCACCTGGCAGGCCCAACCCCCCCCCACCCC TCCCCCGCCGTGTGTGGCCCCTCGCCGCATCGTTGGGGTTTTGTTATGTGAAAATATCCTGGAAATAAATACATGTTTCTGCACTTAGAG |
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FusionGenePPI for MAGED2_SCAMP4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| MAGED2 | MEPCE, RPAP1, TCEA2, ATG2A, PCK1, CUL3, COPS5, TP53, LAGE3, NSMCE4A, EID3, EID1, EID2, MMS19, SOX2, CDK18, CDK20, FKBP5, HSP90AB1, ACLY, HSP90AA1, MCM5, MGEA5, OGFR, SRRT, TPM3, USP7, TRAP1, IRS4, SPRTN, CEP250, TPGS1, C1QBP, TUBB, GIGYF2, HNRNPU, HSPA5, MAGED1, LGALS3BP, TUBG1, TUBGCP3, NAP1L1, NAP1L4, PIK3C2A, PJA2, TUBA1A, TUBA1C, TUBA4A, TUBB4B, UBB, XRN2, RNF2, JAK3, GNAS, RPS6KB2, NTRK1, XPO1, PRKCI, NCSTN, ZNF281, TMEM63B, TIGD6, ARMC6, TGS1, MCM2, SNW1, OTUB1, DNAJB1, NCL, ZNF746, EGFR, GNAL, RIC8B, INTU, CYLD, DLST, TRIM25, G3BP1, TES | SCAMP4 | ELAVL1, TMEM17, CREB3, REEP5, GDPD5, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for MAGED2_SCAMP4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MAGED2_SCAMP4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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