	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 20435

FusionGeneSummary for LY6G5B_MICB

Fusion gene summary

Fusion gene information	Fusion gene name: LY6G5B_MICB
	Fusion gene ID: 20435
		Hgene	Tgene
	Gene symbol	LY6G5B	MICB
	Gene ID	58496	4277
	Gene name	lymphocyte antigen 6 family member G5B	MHC class I polypeptide-related sequence B
	Synonyms	C6orf19\|G5b	PERB11.2
	Cytomap	6p21.33	6p21.33
	Type of gene	protein-coding	protein-coding
	Description	lymphocyte antigen 6 complex locus protein G5blymphocyte antigen 6 complex, locus G5Blymphocyte antigen-6 G5B splicing isoform 288lymphocyte antigen-6 G5B splicing isoform 452lymphocyte antigen-6 G5B splicing isoform 690lymphocyte antigen-6 G5B splic	MHC class I polypeptide-related sequence BMHC class I chain-related protein BMHC class I mic-B antigenMHC class I-like molecule PERB11.2-IMXstress inducible class I homolog
	Modification date	20180519	20180523
	UniProtAcc	Q8NDX9	Q29980
	Ensembl transtripts involved in fusion gene	ENST00000375864, ENST00000409525, ENST00000471088, ENST00000480530, ENST00000484964, ENST00000556456, ENST00000437674, ENST00000383429, ENST00000480515, ENST00000456439,	ENST00000538442, ENST00000399150, ENST00000252229, ENST00000427115, ENST00000442104, ENST00000451603, ENST00000546706, ENST00000438954, ENST00000458032, ENST00000551950, ENST00000437651, ENST00000383514, ENST00000551608, ENST00000436531, ENST00000436655, ENST00000547574, ENST00000400313, ENST00000428416, ENST00000549014, ENST00000428059, ENST00000451789, ENST00000443156, ENST00000551960,
Fusion gene scores	* DoF score	1 X 1 X 1=1	6 X 4 X 4=96
	# samples	1	6
	** MAII score	log2(1/1*10)=3.32192809488736	log2(6/96*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: LY6G5B [Title/Abstract] AND MICB [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	LY6G5B	GO:0051260	protein homooligomerization	17008713
Tgene	MICB	GO:0002429	immune response-activating cell surface receptor signaling pathway	11491531
Tgene	MICB	GO:0006979	response to oxidative stress	11287116
Tgene	MICB	GO:0009408	response to heat	9497295
Tgene	MICB	GO:0032526	response to retinoic acid	12569559
Tgene	MICB	GO:0046629	gamma-delta T cell activation	9497295
Tgene	MICB	GO:0050689	negative regulation of defense response to virus by host	11239445\|12782710

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	LD	LIHC	TCGA-CC-A8HT-01A	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000375864	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-5UTR	ENST00000375864	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-5UTR	ENST00000375864	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000375864	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-5UTR	ENST00000409525	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-5UTR	ENST00000409525	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-5UTR	ENST00000409525	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
5CDS-intron	ENST00000409525	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000471088	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000471088	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000471088	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000471088	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480530	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480530	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480530	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480530	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000484964	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000484964	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000484964	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000484964	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000556456	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000556456	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000556456	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000556456	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000437674	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000437674	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000437674	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000437674	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000383429	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000383429	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000383429	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000383429	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480515	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480515	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000480515	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000480515	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000456439	ENST00000538442	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000456439	ENST00000399150	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-5UTR	ENST00000456439	ENST00000252229	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000427115	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000442104	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000451603	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000546706	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000438954	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000458032	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000551950	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000437651	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000383514	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000551608	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000436531	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000436655	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000547574	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000400313	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000428416	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000549014	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000428059	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000451789	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000443156	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+
intron-intron	ENST00000456439	ENST00000551960	LY6G5B	chr6	31639061	+	MICB	chr6	31473394	+

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FusionProtFeatures for LY6G5B_MICB

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
LY6G5B Q8NDX9	MICB Q29980

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for LY6G5B_MICB

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for LY6G5B_MICB

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene	Hgene's interactors	Tgene	Tgene's interactors
LY6G5B	FN1, VCAM1, CEP57, NEDD1, TP53, TUBGCP3, CDC14B, RNGTT	MICB	ELAVL1, ZCCHC8, EGFR, TRIM25

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for LY6G5B_MICB

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for LY6G5B_MICB

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	MICB	C0019100	Severe Dengue	1	CTD_human
Tgene	MICB	C0036341	Schizophrenia	1	PSYGENET

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Fusion gene ID: 20435

FusionGeneSummary for LY6G5B_MICB

FusionProtFeatures for LY6G5B_MICB

FusionGeneSequence for LY6G5B_MICB

FusionGenePPI for LY6G5B_MICB

RelatedDrugs for LY6G5B_MICB

RelatedDiseases for LY6G5B_MICB