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Fusion gene ID: 20425 |
FusionGeneSummary for LUZP1_NEDD4L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LUZP1_NEDD4L | Fusion gene ID: 20425 | Hgene | Tgene | Gene symbol | LUZP1 | NEDD4L | Gene ID | 7798 | 23327 |
| Gene name | leucine zipper protein 1 | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | |
| Synonyms | LUZP | NEDD4-2|NEDD4.2|PVNH7|RSP5|hNEDD4-2 | |
| Cytomap | 1p36.12 | 18q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | leucine zipper protein 1 | E3 ubiquitin-protein ligase NEDD4-likeHECT-type E3 ubiquitin transferase NED4Lubiquitin-protein ligase Rsp5 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q86V48 | Q96PU5 | |
| Ensembl transtripts involved in fusion gene | ENST00000418342, ENST00000302291, ENST00000314174, ENST00000374623, | ENST00000356462, ENST00000400345, ENST00000589054, ENST00000256832, ENST00000382850, ENST00000256830, ENST00000588516, ENST00000456986, ENST00000435432, ENST00000357895, ENST00000586263, ENST00000456173, ENST00000431212, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 13 X 14 X 6=1092 |
| # samples | 5 | 16 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/1092*10)=-2.77082904603249 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LUZP1 [Title/Abstract] AND NEDD4L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NEDD4L | GO:0003254 | regulation of membrane depolarization | 15217910 |
| Tgene | NEDD4L | GO:0006511 | ubiquitin-dependent protein catabolic process | 21463633 |
| Tgene | NEDD4L | GO:0010038 | response to metal ion | 11244092 |
| Tgene | NEDD4L | GO:0016567 | protein ubiquitination | 15217910|25631046 |
| Tgene | NEDD4L | GO:0034765 | regulation of ion transmembrane transport | 17289006 |
| Tgene | NEDD4L | GO:0042391 | regulation of membrane potential | 17289006 |
| Tgene | NEDD4L | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 21463633 |
| Tgene | NEDD4L | GO:0060306 | regulation of membrane repolarization | 21463633 |
| Tgene | NEDD4L | GO:0070936 | protein K48-linked ubiquitination | 21463633 |
| Tgene | NEDD4L | GO:1901016 | regulation of potassium ion transmembrane transporter activity | 17289006 |
| Tgene | NEDD4L | GO:1901017 | negative regulation of potassium ion transmembrane transporter activity | 21463633 |
| Tgene | NEDD4L | GO:1901380 | negative regulation of potassium ion transmembrane transport | 21463633 |
| Tgene | NEDD4L | GO:1902306 | negative regulation of sodium ion transmembrane transport | 15217910 |
| Tgene | NEDD4L | GO:1903861 | positive regulation of dendrite extension | 23999003 |
| Tgene | NEDD4L | GO:2000009 | negative regulation of protein localization to cell surface | 21463633 |
| Tgene | NEDD4L | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity | 15217910 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-CU-A0YO-01A | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000418342 | ENST00000356462 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| Frame-shift | ENST00000418342 | ENST00000400345 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000418342 | ENST00000589054 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000256832 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000382850 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000256830 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000418342 | ENST00000588516 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000456986 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000435432 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000357895 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000586263 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000456173 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000418342 | ENST00000431212 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| Frame-shift | ENST00000302291 | ENST00000356462 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| Frame-shift | ENST00000302291 | ENST00000400345 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000302291 | ENST00000589054 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000256832 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000382850 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000256830 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000302291 | ENST00000588516 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000456986 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000435432 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000357895 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000586263 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000456173 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000302291 | ENST00000431212 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| In-frame | ENST00000314174 | ENST00000356462 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| In-frame | ENST00000314174 | ENST00000400345 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000314174 | ENST00000589054 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000256832 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000382850 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000256830 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000314174 | ENST00000588516 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000456986 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000435432 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000357895 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000586263 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000456173 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000314174 | ENST00000431212 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| Frame-shift | ENST00000374623 | ENST00000356462 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| Frame-shift | ENST00000374623 | ENST00000400345 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000374623 | ENST00000589054 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000256832 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000382850 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000256830 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-intron | ENST00000374623 | ENST00000588516 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000456986 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000435432 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000357895 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000586263 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000456173 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
| 5CDS-5UTR | ENST00000374623 | ENST00000431212 | LUZP1 | chr1 | 23417683 | - | NEDD4L | chr18 | 55919233 | + |
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FusionProtFeatures for LUZP1_NEDD4L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LUZP1 | NEDD4L |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for LUZP1_NEDD4L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000356462_chr18_55919233_+_1855aa MAEFTSYKETASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCR LMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLA SELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENE TRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEG EDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNNENYSLSNRQVSSPSFTNRRAAKASHMGVSTDSGTQETKK TEDRFVPGSSQSEGKKSREQPSVLSRYPPAAQEHSKAWKGTSKPGTESGLKGKVEKTTRTFSDTTHGSVPSDPLGRADKASDTSSETVFG KRGHVLGNGSQVTQAANSGCSKAIGALASSRRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPYSCRSQENILQGFSTSHKEGVNQP AAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKPQPNSREKAKTRGAPRTSLFENDKDAGMENESVKS VRASTNTMELPDTNGAGVKSQRPFSPREALRSRAIIKPVIVDKDVKKIMGGSGTETTLEKQKPVSKPGPNKVTSSITIYPSDSSSPRAAP GEALRERHTSTSNIQVGLAELTSVSNHVSSPFELSIHKHDITLQLAEAERMADGPLKDRPETVVSRSSIIIKPSDPVERNSHAPPAETIR WKSHSAPSEVGFSDARHVTVRNAWKSRRDLKSLEDPPTRIGKNVESTNSNAYTQRSSTDFSELEQPRSCLFEQGTRRVGPSSGDAPEPSS RRTQSSLTVSEVLTRRNRVGDTITVAAWNHSASMVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRS HKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLM DVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQI TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVK DTLSNPQSPQPSPYNSPKPQHKVTQSFLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLD GRTFYIDHNSKITQWEDPRLQNPAITGPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIE FESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLG KQITLNDMESVDSEYYNSLKWILENDPTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGF TELLPIDLIKIFDENELELLMCGLGDVDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNG >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000400345_chr18_55919233_+_1919aa MAEFTSYKETASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCR LMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLA SELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENE TRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEG EDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNNENYSLSNRQVSSPSFTNRRAAKASHMGVSTDSGTQETKK TEDRFVPGSSQSEGKKSREQPSVLSRYPPAAQEHSKAWKGTSKPGTESGLKGKVEKTTRTFSDTTHGSVPSDPLGRADKASDTSSETVFG KRGHVLGNGSQVTQAANSGCSKAIGALASSRRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPYSCRSQENILQGFSTSHKEGVNQP AAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKPQPNSREKAKTRGAPRTSLFENDKDAGMENESVKS VRASTNTMELPDTNGAGVKSQRPFSPREALRSRAIIKPVIVDKDVKKIMGGSGTETTLEKQKPVSKPGPNKVTSSITIYPSDSSSPRAAP GEALRERHTSTSNIQVGLAELTSVSNHVSSPFELSIHKHDITLQLAEAERMADGPLKDRPETVVSRSSIIIKPSDPVERNSHAPPAETIR WKSHSAPSEVGFSDARHVTVRNAWKSRRDLKSLEDPPTRIGKNVESTNSNAYTQRSSTDFSELEQPRSCLFEQGTRRVGPSSGDAPEPSS RRTQSSLTVSEVLTRRNRVGDTITVAAWNHSASMVNPSNHRLLFEVFDENRLTRDDFLGQVDVPLSHLPTEDPTMERPYTFKDFLLRPRS HKSRVKGFLRLKMAYMPKNGGQDEENSDQRDDMEHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLM DVSSESDNNIRQINQEAAHRRFRSRRHISEDLEPEPSEGGDVPEPWETISEEVNIAGDSLGLALPPPPASPGSRTSPQELSEELSRRLQI TPDSNGEQFSSLIQREPSSRLRSCSVTDAVAEQGHLPPPSAPAGRARSSTVTGGEEPTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHN NRTTTWTRPIMQLAEDGASGSATNSNNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHKVTQS FLPPGWEMRIAPNGRPFFIDHNTKTTTWEDPRLKFPVHMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQNPAIT GPAVPYSREFKQKYDYFRKKLKKPADIPNRFEMKLHRNNIFEESYRRIMSVKRPDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFN PYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFTFIGRVAGLAVFHGKLLDGFFIRPFYKMMLGKQITLNDMESVDSEYYNSLKWILEND PTELDLMFCIDEENFGQTYQVDLKPNGSEIMVTNENKREYIDLVIQWRFVNRVQKQMNAFLEGFTELLPIDLIKIFDENELELLMCGLGD VDVNDWRQHSIYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000356462_chr18_55919233_+_5565nt ATGGCCGAATTTACAAGCTACAAGGAGACGGCCTCCAGCCGCCACTTGCGGTTTAAGCTACAGAGTCTAAGCCGCCGCCTTGATGAGTTG GAGGAAGCCACAAAAAACCTCCAGAAAGCAGAGGATGAACTCCTGGATCTCCAGGACAAGGTGATTCAGGCAGAAGGTAGCAACTCCAGC ATGTTGGCGGAGATTGAAGTGCTGCGCCAGCGGGTGCTGAGAATTGAAGGCAAAGACGAGGAAATTAAGAGAGCAGAGGATCTGTGTCGT CTGATGAAGGAGAAACTTGAAGAGGAAGAAAACCTCACCCGGGAGCTGAAATCTGAGATTGAGCGGCTTCAGAAACGAATGGCTGAATTA GAGAAGCTAGAAGAGGCCTTCAGCAGGAGTAAGAATGACTGTACCCAGCTGTGTCTGAGCCTGAATGAGGAGAGAAATCTGACCAAGAAA ATCTCCTCTGAGCTGGAAATGCTCAGAGTCAAAGTGAAAGAACTAGAATCTTCTGAGGACCGCCTGGATAAAACTGAGCAGAGTTTAGCG TCAGAGTTAGAAAAGCTGAAATCATTAACTCTGAGCTTTGTAAGTGAGAGAAAATACTTGAATGAAAAGGAGAAAGAAAATGAGAAATTG ATAAAAGAACTCACTCAAAAACTAGAGCAGAACAAAAAAATGAACCGAGATTATACAAGGAATGCTTCTAATCTGGAAAGAAATGACCTA CGGATTGAGGATGGCATCTCTTCCACACTGCCGTCCAAAGAATCAAGAAGGAAGGGTGGTCTGGACTACCTAAAGCAGGTAGAGAATGAA ACAAGAAACAAATCAGAAAATGAAAAGAACCGCAATCAGGAAGACAACAAAGTCAAAGACCTTAACCAAGAGATTGAGAAACTTAAGACA CAAATCAAACACTTTGAATCGTTGGAAGAAGAGCTTAAGAAAATGAAGTCCAAAAATAACGACCTTCAGGATAATTACCTAAGTGAACAA AATAAAAACAAATTATTAGCCAGCCAACTGGAGGAGATAAAGCTACAAATCAAGAAACAGAAAGAGTTAGAAAATGGAGAGGTAGAAGGG GAAGATGCTTTCCTGTCCAGCAAAGGCAGACATGAGAGGACTAAGTTTAGAGGCCACGGAAGTGAAGCTTCTGTGTCCAAGCACACAGCG CGGGAACTGTCTCCTCAGCATAAGCGGGAACGACTCCGGAACAGGGAGTTTGCTCTCAACAATGAAAACTATTCTCTGAGCAACAGGCAG GTTTCTTCTCCCAGTTTCACCAACAGGAGGGCAGCAAAAGCTTCTCACATGGGGGTGAGTACAGACAGTGGGACTCAGGAGACAAAGAAA ACTGAAGACCGGTTTGTACCCGGCTCCTCCCAGAGCGAAGGGAAGAAGTCTAGGGAGCAGCCCTCAGTGCTGAGTCGCTACCCCCCGGCT GCTCAGGAGCACAGTAAAGCGTGGAAGGGGACTTCCAAGCCAGGCACCGAGAGCGGACTGAAGGGAAAAGTGGAGAAGACAACACGAACG TTTAGTGACACCACCCATGGATCTGTTCCCAGTGACCCATTGGGTAGAGCTGACAAGGCTTCTGACACCTCCTCTGAGACTGTCTTTGGC AAGAGGGGACACGTGCTTGGCAACGGAAGTCAAGTAACTCAGGCTGCAAACTCTGGCTGTTCTAAGGCCATTGGAGCCCTGGCCTCATCT CGAAGATCCTCCTCAGAAGGGCTCTCTAAAGGCAAAAAGGCTGCCAATGGCCTTGAGGCTGATAACAGTTGCCCGAATTCCAAGGCTCCT GTTCTATCGAAGTATCCTTATAGCTGTAGAAGCCAAGAGAACATCCTTCAGGGATTTTCAACCTCACATAAAGAAGGGGTTAATCAACCT GCAGCAGTTGTGATGGAAGACAGCAGTCCGCATGAAGCCTTGAGGTGTCGAGTCATCAAATCCAGTGGCAGAGAGAAGCCAGACTCAGAT GATGACTTGGACATAGCATCTCTTGTTACTGCCAAGTTGGTAAATACAACCATCACTCCAGAGCCAGAGCCCAAACCACAGCCTAACTCT AGAGAAAAGGCTAAAACCCGAGGGGCACCTAGAACCTCCCTATTTGAGAATGATAAAGATGCTGGAATGGAGAATGAATCTGTGAAATCT GTCAGAGCCTCCACCAATACCATGGAGCTCCCAGATACCAATGGTGCTGGGGTAAAAAGCCAAAGGCCCTTTAGCCCCAGAGAGGCGTTG CGGTCTAGAGCCATCATCAAACCTGTTATTGTTGATAAGGATGTGAAAAAAATCATGGGAGGATCTGGAACAGAGACTACGTTGGAGAAA CAGAAACCCGTCTCCAAACCAGGGCCAAACAAAGTGACAAGTAGCATTACTATATATCCATCTGACAGCAGCAGCCCCAGAGCTGCTCCG GGTGAGGCCCTGAGGGAGAGGCACACATCCACTAGCAATATCCAGGTGGGGCTGGCAGAGCTCACATCAGTTAGCAACCATGTCAGCTCC CCTTTTGAGCTCTCCATTCACAAACATGACATCACCCTGCAGCTTGCAGAAGCGGAGAGAATGGCAGATGGGCCCCTGAAGGACAGGCCA GAAACAGTGGTCTCTCGGAGCAGCATTATAATCAAGCCATCGGATCCTGTGGAGAGGAATAGCCATGCACCTCCAGCGGAGACAATCAGG TGGAAAAGCCATAGTGCCCCTTCAGAAGTGGGCTTCTCAGATGCCAGACATGTTACTGTGCGGAATGCCTGGAAGAGTAGGCGAGACTTG AAATCTTTAGAAGACCCCCCAACTCGAATAGGTAAAAACGTGGAATCTACCAATAGCAATGCCTACACCCAGAGGTCTTCCACAGACTTC TCAGAACTCGAACAGCCCAGGTCCTGCCTTTTTGAGCAGGGCACTCGAAGGGTAGGACCAAGTTCAGGGGATGCCCCTGAGCCCTCCTCC AGAAGGACCCAAAGTAGCCTCACTGTGTCAGAGGTGCTTACCCGTCGGAATCGGGTAGGAGACACCATCACTGTCGCAGCCTGGAACCAC TCAGCAAGCATGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAG GTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGT CATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGG GATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCC GGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATG GACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAA GACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTC GGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATC ACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTT GCAGAACAGGGCCATCTACCACCGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATC CGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAA GACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCC GGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAA TTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGAT GGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTC CCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAA CTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAG TTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGC CTCTTTGAGTACTCTGCCACGGACAACTACACCCTTCAGATCAACCCTAATTCAGGCCTCTGTAATGAGGATCATTTGTCCTACTTCACT TTTATTGGAAGAGTTGCTGGTCTGGCCGTATTTCATGGGAAGCTCTTAGATGGTTTCTTCATTAGACCATTTTACAAGATGATGTTGGGA AAGCAGATAACCCTGAATGACATGGAATCTGTGGATAGTGAATATTACAACTCTTTGAAATGGATCCTGGAGAATGACCCTACTGAGCTG GACCTCATGTTCTGCATAGACGAAGAAAACTTTGGACAGACATATCAAGTGGATTTGAAGCCCAATGGGTCAGAAATAATGGTCACAAAT GAAAACAAAAGGGAATATATCGACTTAGTCATCCAGTGGAGATTTGTGAACAGGGTCCAGAAGCAGATGAACGCCTTCTTGGAGGGATTC ACAGAACTACTTCCTATTGATTTGATTAAAATTTTTGATGAAAATGAGCTGGAGTTGCTCATGTGCGGCCTCGGTGATGTGGATGTGAAT GACTGGAGACAGCATTCTATTTACAAGAACGGCTACTGCCCAAACCACCCCGTCATTCAGTGGTTCTGGAAGGCTGTGCTACTCATGGAC GCCGAAAAGCGTATCCGGTTACTGCAGTTTGTCACAGGGACATCGCGAGTACCTATGAATGGATTTGCCGAACTTTATGGTTCCAATGGT CCTCAGCTGTTTACAATAGAGCAATGGGGCAGTCCTGAGAAACTGCCCAGAGCTCACACATGCTTTAATCGCCTTGACTTACCTCCATAT >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000400345_chr18_55919233_+_5757nt ATGGCCGAATTTACAAGCTACAAGGAGACGGCCTCCAGCCGCCACTTGCGGTTTAAGCTACAGAGTCTAAGCCGCCGCCTTGATGAGTTG GAGGAAGCCACAAAAAACCTCCAGAAAGCAGAGGATGAACTCCTGGATCTCCAGGACAAGGTGATTCAGGCAGAAGGTAGCAACTCCAGC ATGTTGGCGGAGATTGAAGTGCTGCGCCAGCGGGTGCTGAGAATTGAAGGCAAAGACGAGGAAATTAAGAGAGCAGAGGATCTGTGTCGT CTGATGAAGGAGAAACTTGAAGAGGAAGAAAACCTCACCCGGGAGCTGAAATCTGAGATTGAGCGGCTTCAGAAACGAATGGCTGAATTA GAGAAGCTAGAAGAGGCCTTCAGCAGGAGTAAGAATGACTGTACCCAGCTGTGTCTGAGCCTGAATGAGGAGAGAAATCTGACCAAGAAA ATCTCCTCTGAGCTGGAAATGCTCAGAGTCAAAGTGAAAGAACTAGAATCTTCTGAGGACCGCCTGGATAAAACTGAGCAGAGTTTAGCG TCAGAGTTAGAAAAGCTGAAATCATTAACTCTGAGCTTTGTAAGTGAGAGAAAATACTTGAATGAAAAGGAGAAAGAAAATGAGAAATTG ATAAAAGAACTCACTCAAAAACTAGAGCAGAACAAAAAAATGAACCGAGATTATACAAGGAATGCTTCTAATCTGGAAAGAAATGACCTA CGGATTGAGGATGGCATCTCTTCCACACTGCCGTCCAAAGAATCAAGAAGGAAGGGTGGTCTGGACTACCTAAAGCAGGTAGAGAATGAA ACAAGAAACAAATCAGAAAATGAAAAGAACCGCAATCAGGAAGACAACAAAGTCAAAGACCTTAACCAAGAGATTGAGAAACTTAAGACA CAAATCAAACACTTTGAATCGTTGGAAGAAGAGCTTAAGAAAATGAAGTCCAAAAATAACGACCTTCAGGATAATTACCTAAGTGAACAA AATAAAAACAAATTATTAGCCAGCCAACTGGAGGAGATAAAGCTACAAATCAAGAAACAGAAAGAGTTAGAAAATGGAGAGGTAGAAGGG GAAGATGCTTTCCTGTCCAGCAAAGGCAGACATGAGAGGACTAAGTTTAGAGGCCACGGAAGTGAAGCTTCTGTGTCCAAGCACACAGCG CGGGAACTGTCTCCTCAGCATAAGCGGGAACGACTCCGGAACAGGGAGTTTGCTCTCAACAATGAAAACTATTCTCTGAGCAACAGGCAG GTTTCTTCTCCCAGTTTCACCAACAGGAGGGCAGCAAAAGCTTCTCACATGGGGGTGAGTACAGACAGTGGGACTCAGGAGACAAAGAAA ACTGAAGACCGGTTTGTACCCGGCTCCTCCCAGAGCGAAGGGAAGAAGTCTAGGGAGCAGCCCTCAGTGCTGAGTCGCTACCCCCCGGCT GCTCAGGAGCACAGTAAAGCGTGGAAGGGGACTTCCAAGCCAGGCACCGAGAGCGGACTGAAGGGAAAAGTGGAGAAGACAACACGAACG TTTAGTGACACCACCCATGGATCTGTTCCCAGTGACCCATTGGGTAGAGCTGACAAGGCTTCTGACACCTCCTCTGAGACTGTCTTTGGC AAGAGGGGACACGTGCTTGGCAACGGAAGTCAAGTAACTCAGGCTGCAAACTCTGGCTGTTCTAAGGCCATTGGAGCCCTGGCCTCATCT CGAAGATCCTCCTCAGAAGGGCTCTCTAAAGGCAAAAAGGCTGCCAATGGCCTTGAGGCTGATAACAGTTGCCCGAATTCCAAGGCTCCT GTTCTATCGAAGTATCCTTATAGCTGTAGAAGCCAAGAGAACATCCTTCAGGGATTTTCAACCTCACATAAAGAAGGGGTTAATCAACCT GCAGCAGTTGTGATGGAAGACAGCAGTCCGCATGAAGCCTTGAGGTGTCGAGTCATCAAATCCAGTGGCAGAGAGAAGCCAGACTCAGAT GATGACTTGGACATAGCATCTCTTGTTACTGCCAAGTTGGTAAATACAACCATCACTCCAGAGCCAGAGCCCAAACCACAGCCTAACTCT AGAGAAAAGGCTAAAACCCGAGGGGCACCTAGAACCTCCCTATTTGAGAATGATAAAGATGCTGGAATGGAGAATGAATCTGTGAAATCT GTCAGAGCCTCCACCAATACCATGGAGCTCCCAGATACCAATGGTGCTGGGGTAAAAAGCCAAAGGCCCTTTAGCCCCAGAGAGGCGTTG CGGTCTAGAGCCATCATCAAACCTGTTATTGTTGATAAGGATGTGAAAAAAATCATGGGAGGATCTGGAACAGAGACTACGTTGGAGAAA CAGAAACCCGTCTCCAAACCAGGGCCAAACAAAGTGACAAGTAGCATTACTATATATCCATCTGACAGCAGCAGCCCCAGAGCTGCTCCG GGTGAGGCCCTGAGGGAGAGGCACACATCCACTAGCAATATCCAGGTGGGGCTGGCAGAGCTCACATCAGTTAGCAACCATGTCAGCTCC CCTTTTGAGCTCTCCATTCACAAACATGACATCACCCTGCAGCTTGCAGAAGCGGAGAGAATGGCAGATGGGCCCCTGAAGGACAGGCCA GAAACAGTGGTCTCTCGGAGCAGCATTATAATCAAGCCATCGGATCCTGTGGAGAGGAATAGCCATGCACCTCCAGCGGAGACAATCAGG TGGAAAAGCCATAGTGCCCCTTCAGAAGTGGGCTTCTCAGATGCCAGACATGTTACTGTGCGGAATGCCTGGAAGAGTAGGCGAGACTTG AAATCTTTAGAAGACCCCCCAACTCGAATAGGTAAAAACGTGGAATCTACCAATAGCAATGCCTACACCCAGAGGTCTTCCACAGACTTC TCAGAACTCGAACAGCCCAGGTCCTGCCTTTTTGAGCAGGGCACTCGAAGGGTAGGACCAAGTTCAGGGGATGCCCCTGAGCCCTCCTCC AGAAGGACCCAAAGTAGCCTCACTGTGTCAGAGGTGCTTACCCGTCGGAATCGGGTAGGAGACACCATCACTGTCGCAGCCTGGAACCAC TCAGCAAGCATGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAG GTGGACGTGCCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGT CATAAGTCTCGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGG GATGACATGGAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCC GGGTGGGAAGAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATG GACGTGTCCTCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAA GACTTGGAGCCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTC GGTCTGGCTCTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATC ACTCCAGACTCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTT GCAGAACAGGGCCATCTACCACCGCCCAGTGCCCCAGCTGGGAGAGCGCGTTCATCAACTGTCACGGGTGGTGAGGAACCAACGCCATCA GTGGCCTATGTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAAC AATCGAACCACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATC GAGCCTCAGATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGT CGGGCTGTGAAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGC TTCTTGCCACCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGAT CCACGTTTGAAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGA ATTCACTTGGATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACT GGTCCGGCTGTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGG TTTGAAATGAAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGA CTGTGGATTGAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAAC CCCTACTACGGCCTCTTTGAGTACTCTGCCACGGACAACTACACCCTTCAGATCAACCCTAATTCAGGCCTCTGTAATGAGGATCATTTG TCCTACTTCACTTTTATTGGAAGAGTTGCTGGTCTGGCCGTATTTCATGGGAAGCTCTTAGATGGTTTCTTCATTAGACCATTTTACAAG ATGATGTTGGGAAAGCAGATAACCCTGAATGACATGGAATCTGTGGATAGTGAATATTACAACTCTTTGAAATGGATCCTGGAGAATGAC CCTACTGAGCTGGACCTCATGTTCTGCATAGACGAAGAAAACTTTGGACAGACATATCAAGTGGATTTGAAGCCCAATGGGTCAGAAATA ATGGTCACAAATGAAAACAAAAGGGAATATATCGACTTAGTCATCCAGTGGAGATTTGTGAACAGGGTCCAGAAGCAGATGAACGCCTTC TTGGAGGGATTCACAGAACTACTTCCTATTGATTTGATTAAAATTTTTGATGAAAATGAGCTGGAGTTGCTCATGTGCGGCCTCGGTGAT GTGGATGTGAATGACTGGAGACAGCATTCTATTTACAAGAACGGCTACTGCCCAAACCACCCCGTCATTCAGTGGTTCTGGAAGGCTGTG CTACTCATGGACGCCGAAAAGCGTATCCGGTTACTGCAGTTTGTCACAGGGACATCGCGAGTACCTATGAATGGATTTGCCGAACTTTAT GGTTCCAATGGTCCTCAGCTGTTTACAATAGAGCAATGGGGCAGTCCTGAGAAACTGCCCAGAGCTCACACATGCTTTAATCGCCTTGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000356462_chr18_55919233_+_6041nt AGCTGAGCGGCGGAACCCTTCGCTGGCGGGAGCGCGGTTCGGGGCCGCAGAGATTGATGATGGTCTCCAGCTGTCAAAGAAGATTGTGGT TGCCAAGAGAAAGGTAACCATTTCTCATCCCCTTGAGTGGAATTGGATGCCTCTAGGAGCCCACATTGGCTGGCAGTAGACATGGCCGAA TTTACAAGCTACAAGGAGACGGCCTCCAGCCGCCACTTGCGGTTTAAGCTACAGAGTCTAAGCCGCCGCCTTGATGAGTTGGAGGAAGCC ACAAAAAACCTCCAGAAAGCAGAGGATGAACTCCTGGATCTCCAGGACAAGGTGATTCAGGCAGAAGGTAGCAACTCCAGCATGTTGGCG GAGATTGAAGTGCTGCGCCAGCGGGTGCTGAGAATTGAAGGCAAAGACGAGGAAATTAAGAGAGCAGAGGATCTGTGTCGTCTGATGAAG GAGAAACTTGAAGAGGAAGAAAACCTCACCCGGGAGCTGAAATCTGAGATTGAGCGGCTTCAGAAACGAATGGCTGAATTAGAGAAGCTA GAAGAGGCCTTCAGCAGGAGTAAGAATGACTGTACCCAGCTGTGTCTGAGCCTGAATGAGGAGAGAAATCTGACCAAGAAAATCTCCTCT GAGCTGGAAATGCTCAGAGTCAAAGTGAAAGAACTAGAATCTTCTGAGGACCGCCTGGATAAAACTGAGCAGAGTTTAGCGTCAGAGTTA GAAAAGCTGAAATCATTAACTCTGAGCTTTGTAAGTGAGAGAAAATACTTGAATGAAAAGGAGAAAGAAAATGAGAAATTGATAAAAGAA CTCACTCAAAAACTAGAGCAGAACAAAAAAATGAACCGAGATTATACAAGGAATGCTTCTAATCTGGAAAGAAATGACCTACGGATTGAG GATGGCATCTCTTCCACACTGCCGTCCAAAGAATCAAGAAGGAAGGGTGGTCTGGACTACCTAAAGCAGGTAGAGAATGAAACAAGAAAC AAATCAGAAAATGAAAAGAACCGCAATCAGGAAGACAACAAAGTCAAAGACCTTAACCAAGAGATTGAGAAACTTAAGACACAAATCAAA CACTTTGAATCGTTGGAAGAAGAGCTTAAGAAAATGAAGTCCAAAAATAACGACCTTCAGGATAATTACCTAAGTGAACAAAATAAAAAC AAATTATTAGCCAGCCAACTGGAGGAGATAAAGCTACAAATCAAGAAACAGAAAGAGTTAGAAAATGGAGAGGTAGAAGGGGAAGATGCT TTCCTGTCCAGCAAAGGCAGACATGAGAGGACTAAGTTTAGAGGCCACGGAAGTGAAGCTTCTGTGTCCAAGCACACAGCGCGGGAACTG TCTCCTCAGCATAAGCGGGAACGACTCCGGAACAGGGAGTTTGCTCTCAACAATGAAAACTATTCTCTGAGCAACAGGCAGGTTTCTTCT CCCAGTTTCACCAACAGGAGGGCAGCAAAAGCTTCTCACATGGGGGTGAGTACAGACAGTGGGACTCAGGAGACAAAGAAAACTGAAGAC CGGTTTGTACCCGGCTCCTCCCAGAGCGAAGGGAAGAAGTCTAGGGAGCAGCCCTCAGTGCTGAGTCGCTACCCCCCGGCTGCTCAGGAG CACAGTAAAGCGTGGAAGGGGACTTCCAAGCCAGGCACCGAGAGCGGACTGAAGGGAAAAGTGGAGAAGACAACACGAACGTTTAGTGAC ACCACCCATGGATCTGTTCCCAGTGACCCATTGGGTAGAGCTGACAAGGCTTCTGACACCTCCTCTGAGACTGTCTTTGGCAAGAGGGGA CACGTGCTTGGCAACGGAAGTCAAGTAACTCAGGCTGCAAACTCTGGCTGTTCTAAGGCCATTGGAGCCCTGGCCTCATCTCGAAGATCC TCCTCAGAAGGGCTCTCTAAAGGCAAAAAGGCTGCCAATGGCCTTGAGGCTGATAACAGTTGCCCGAATTCCAAGGCTCCTGTTCTATCG AAGTATCCTTATAGCTGTAGAAGCCAAGAGAACATCCTTCAGGGATTTTCAACCTCACATAAAGAAGGGGTTAATCAACCTGCAGCAGTT GTGATGGAAGACAGCAGTCCGCATGAAGCCTTGAGGTGTCGAGTCATCAAATCCAGTGGCAGAGAGAAGCCAGACTCAGATGATGACTTG GACATAGCATCTCTTGTTACTGCCAAGTTGGTAAATACAACCATCACTCCAGAGCCAGAGCCCAAACCACAGCCTAACTCTAGAGAAAAG GCTAAAACCCGAGGGGCACCTAGAACCTCCCTATTTGAGAATGATAAAGATGCTGGAATGGAGAATGAATCTGTGAAATCTGTCAGAGCC TCCACCAATACCATGGAGCTCCCAGATACCAATGGTGCTGGGGTAAAAAGCCAAAGGCCCTTTAGCCCCAGAGAGGCGTTGCGGTCTAGA GCCATCATCAAACCTGTTATTGTTGATAAGGATGTGAAAAAAATCATGGGAGGATCTGGAACAGAGACTACGTTGGAGAAACAGAAACCC GTCTCCAAACCAGGGCCAAACAAAGTGACAAGTAGCATTACTATATATCCATCTGACAGCAGCAGCCCCAGAGCTGCTCCGGGTGAGGCC CTGAGGGAGAGGCACACATCCACTAGCAATATCCAGGTGGGGCTGGCAGAGCTCACATCAGTTAGCAACCATGTCAGCTCCCCTTTTGAG CTCTCCATTCACAAACATGACATCACCCTGCAGCTTGCAGAAGCGGAGAGAATGGCAGATGGGCCCCTGAAGGACAGGCCAGAAACAGTG GTCTCTCGGAGCAGCATTATAATCAAGCCATCGGATCCTGTGGAGAGGAATAGCCATGCACCTCCAGCGGAGACAATCAGGTGGAAAAGC CATAGTGCCCCTTCAGAAGTGGGCTTCTCAGATGCCAGACATGTTACTGTGCGGAATGCCTGGAAGAGTAGGCGAGACTTGAAATCTTTA GAAGACCCCCCAACTCGAATAGGTAAAAACGTGGAATCTACCAATAGCAATGCCTACACCCAGAGGTCTTCCACAGACTTCTCAGAACTC GAACAGCCCAGGTCCTGCCTTTTTGAGCAGGGCACTCGAAGGGTAGGACCAAGTTCAGGGGATGCCCCTGAGCCCTCCTCCAGAAGGACC CAAAGTAGCCTCACTGTGTCAGAGGTGCTTACCCGTCGGAATCGGGTAGGAGACACCATCACTGTCGCAGCCTGGAACCACTCAGCAAGC ATGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTG CCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCT CGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATG GAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAA GAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCC TCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAG CCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCT CTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGAC TCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAG GGCCATCTACCACCGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAGATCCGCCGGCCT CGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTGAAAGACACCCTT TCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCACCCGGCTGGGAA ATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTGAAATTTCCAGTA CATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTGGATGGCCGAACG TTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCTGTCCCTTACTCC AGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATGAAACTTCACAGA AATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATTGAGTTTGAATCA GAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTACGGCCTCTTTGAG TACTCTGCCACGGACAACTACACCCTTCAGATCAACCCTAATTCAGGCCTCTGTAATGAGGATCATTTGTCCTACTTCACTTTTATTGGA AGAGTTGCTGGTCTGGCCGTATTTCATGGGAAGCTCTTAGATGGTTTCTTCATTAGACCATTTTACAAGATGATGTTGGGAAAGCAGATA ACCCTGAATGACATGGAATCTGTGGATAGTGAATATTACAACTCTTTGAAATGGATCCTGGAGAATGACCCTACTGAGCTGGACCTCATG TTCTGCATAGACGAAGAAAACTTTGGACAGACATATCAAGTGGATTTGAAGCCCAATGGGTCAGAAATAATGGTCACAAATGAAAACAAA AGGGAATATATCGACTTAGTCATCCAGTGGAGATTTGTGAACAGGGTCCAGAAGCAGATGAACGCCTTCTTGGAGGGATTCACAGAACTA CTTCCTATTGATTTGATTAAAATTTTTGATGAAAATGAGCTGGAGTTGCTCATGTGCGGCCTCGGTGATGTGGATGTGAATGACTGGAGA CAGCATTCTATTTACAAGAACGGCTACTGCCCAAACCACCCCGTCATTCAGTGGTTCTGGAAGGCTGTGCTACTCATGGACGCCGAAAAG CGTATCCGGTTACTGCAGTTTGTCACAGGGACATCGCGAGTACCTATGAATGGATTTGCCGAACTTTATGGTTCCAATGGTCCTCAGCTG TTTACAATAGAGCAATGGGGCAGTCCTGAGAAACTGCCCAGAGCTCACACATGCTTTAATCGCCTTGACTTACCTCCATATGAAACCTTT GAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGCCTCGGGGGTGGTT GTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTGCAGGCATGGTCCC TGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCCCACCACAAATTAT CAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTTGTGCCTCTGCAGGCAAAGCCCTTAATAAATATT >In-frame_LUZP1_ENST00000314174_chr1_23417683_-_NEDD4L_ENST00000400345_chr18_55919233_+_6364nt AGCTGAGCGGCGGAACCCTTCGCTGGCGGGAGCGCGGTTCGGGGCCGCAGAGATTGATGATGGTCTCCAGCTGTCAAAGAAGATTGTGGT TGCCAAGAGAAAGGTAACCATTTCTCATCCCCTTGAGTGGAATTGGATGCCTCTAGGAGCCCACATTGGCTGGCAGTAGACATGGCCGAA TTTACAAGCTACAAGGAGACGGCCTCCAGCCGCCACTTGCGGTTTAAGCTACAGAGTCTAAGCCGCCGCCTTGATGAGTTGGAGGAAGCC ACAAAAAACCTCCAGAAAGCAGAGGATGAACTCCTGGATCTCCAGGACAAGGTGATTCAGGCAGAAGGTAGCAACTCCAGCATGTTGGCG GAGATTGAAGTGCTGCGCCAGCGGGTGCTGAGAATTGAAGGCAAAGACGAGGAAATTAAGAGAGCAGAGGATCTGTGTCGTCTGATGAAG GAGAAACTTGAAGAGGAAGAAAACCTCACCCGGGAGCTGAAATCTGAGATTGAGCGGCTTCAGAAACGAATGGCTGAATTAGAGAAGCTA GAAGAGGCCTTCAGCAGGAGTAAGAATGACTGTACCCAGCTGTGTCTGAGCCTGAATGAGGAGAGAAATCTGACCAAGAAAATCTCCTCT GAGCTGGAAATGCTCAGAGTCAAAGTGAAAGAACTAGAATCTTCTGAGGACCGCCTGGATAAAACTGAGCAGAGTTTAGCGTCAGAGTTA GAAAAGCTGAAATCATTAACTCTGAGCTTTGTAAGTGAGAGAAAATACTTGAATGAAAAGGAGAAAGAAAATGAGAAATTGATAAAAGAA CTCACTCAAAAACTAGAGCAGAACAAAAAAATGAACCGAGATTATACAAGGAATGCTTCTAATCTGGAAAGAAATGACCTACGGATTGAG GATGGCATCTCTTCCACACTGCCGTCCAAAGAATCAAGAAGGAAGGGTGGTCTGGACTACCTAAAGCAGGTAGAGAATGAAACAAGAAAC AAATCAGAAAATGAAAAGAACCGCAATCAGGAAGACAACAAAGTCAAAGACCTTAACCAAGAGATTGAGAAACTTAAGACACAAATCAAA CACTTTGAATCGTTGGAAGAAGAGCTTAAGAAAATGAAGTCCAAAAATAACGACCTTCAGGATAATTACCTAAGTGAACAAAATAAAAAC AAATTATTAGCCAGCCAACTGGAGGAGATAAAGCTACAAATCAAGAAACAGAAAGAGTTAGAAAATGGAGAGGTAGAAGGGGAAGATGCT TTCCTGTCCAGCAAAGGCAGACATGAGAGGACTAAGTTTAGAGGCCACGGAAGTGAAGCTTCTGTGTCCAAGCACACAGCGCGGGAACTG TCTCCTCAGCATAAGCGGGAACGACTCCGGAACAGGGAGTTTGCTCTCAACAATGAAAACTATTCTCTGAGCAACAGGCAGGTTTCTTCT CCCAGTTTCACCAACAGGAGGGCAGCAAAAGCTTCTCACATGGGGGTGAGTACAGACAGTGGGACTCAGGAGACAAAGAAAACTGAAGAC CGGTTTGTACCCGGCTCCTCCCAGAGCGAAGGGAAGAAGTCTAGGGAGCAGCCCTCAGTGCTGAGTCGCTACCCCCCGGCTGCTCAGGAG CACAGTAAAGCGTGGAAGGGGACTTCCAAGCCAGGCACCGAGAGCGGACTGAAGGGAAAAGTGGAGAAGACAACACGAACGTTTAGTGAC ACCACCCATGGATCTGTTCCCAGTGACCCATTGGGTAGAGCTGACAAGGCTTCTGACACCTCCTCTGAGACTGTCTTTGGCAAGAGGGGA CACGTGCTTGGCAACGGAAGTCAAGTAACTCAGGCTGCAAACTCTGGCTGTTCTAAGGCCATTGGAGCCCTGGCCTCATCTCGAAGATCC TCCTCAGAAGGGCTCTCTAAAGGCAAAAAGGCTGCCAATGGCCTTGAGGCTGATAACAGTTGCCCGAATTCCAAGGCTCCTGTTCTATCG AAGTATCCTTATAGCTGTAGAAGCCAAGAGAACATCCTTCAGGGATTTTCAACCTCACATAAAGAAGGGGTTAATCAACCTGCAGCAGTT GTGATGGAAGACAGCAGTCCGCATGAAGCCTTGAGGTGTCGAGTCATCAAATCCAGTGGCAGAGAGAAGCCAGACTCAGATGATGACTTG GACATAGCATCTCTTGTTACTGCCAAGTTGGTAAATACAACCATCACTCCAGAGCCAGAGCCCAAACCACAGCCTAACTCTAGAGAAAAG GCTAAAACCCGAGGGGCACCTAGAACCTCCCTATTTGAGAATGATAAAGATGCTGGAATGGAGAATGAATCTGTGAAATCTGTCAGAGCC TCCACCAATACCATGGAGCTCCCAGATACCAATGGTGCTGGGGTAAAAAGCCAAAGGCCCTTTAGCCCCAGAGAGGCGTTGCGGTCTAGA GCCATCATCAAACCTGTTATTGTTGATAAGGATGTGAAAAAAATCATGGGAGGATCTGGAACAGAGACTACGTTGGAGAAACAGAAACCC GTCTCCAAACCAGGGCCAAACAAAGTGACAAGTAGCATTACTATATATCCATCTGACAGCAGCAGCCCCAGAGCTGCTCCGGGTGAGGCC CTGAGGGAGAGGCACACATCCACTAGCAATATCCAGGTGGGGCTGGCAGAGCTCACATCAGTTAGCAACCATGTCAGCTCCCCTTTTGAG CTCTCCATTCACAAACATGACATCACCCTGCAGCTTGCAGAAGCGGAGAGAATGGCAGATGGGCCCCTGAAGGACAGGCCAGAAACAGTG GTCTCTCGGAGCAGCATTATAATCAAGCCATCGGATCCTGTGGAGAGGAATAGCCATGCACCTCCAGCGGAGACAATCAGGTGGAAAAGC CATAGTGCCCCTTCAGAAGTGGGCTTCTCAGATGCCAGACATGTTACTGTGCGGAATGCCTGGAAGAGTAGGCGAGACTTGAAATCTTTA GAAGACCCCCCAACTCGAATAGGTAAAAACGTGGAATCTACCAATAGCAATGCCTACACCCAGAGGTCTTCCACAGACTTCTCAGAACTC GAACAGCCCAGGTCCTGCCTTTTTGAGCAGGGCACTCGAAGGGTAGGACCAAGTTCAGGGGATGCCCCTGAGCCCTCCTCCAGAAGGACC CAAAGTAGCCTCACTGTGTCAGAGGTGCTTACCCGTCGGAATCGGGTAGGAGACACCATCACTGTCGCAGCCTGGAACCACTCAGCAAGC ATGGTAAACCCATCTAATCACAGACTCCTATTTGAAGTATTTGACGAAAATAGACTGACACGAGACGACTTCCTGGGCCAGGTGGACGTG CCCCTTAGTCACCTTCCGACAGAAGATCCAACCATGGAGCGACCCTATACATTTAAGGACTTTCTCCTCAGACCAAGAAGTCATAAGTCT CGAGTTAAGGGATTTTTGCGATTGAAAATGGCCTATATGCCAAAAAATGGAGGTCAAGATGAAGAAAACAGTGACCAGAGGGATGACATG GAGCATGGATGGGAAGTTGTTGACTCAAATGACTCGGCTTCTCAGCACCAAGAGGAACTTCCTCCTCCTCCTCTGCCTCCCGGGTGGGAA GAAAAAGTGGACAATTTAGGCCGAACTTACTATGTCAACCACAACAACCGGACCACTCAGTGGCACAGACCAAGCCTGATGGACGTGTCC TCGGAGTCGGACAATAACATCAGACAGATCAACCAGGAGGCAGCACACCGGCGCTTCCGCTCCCGCAGGCACATCAGCGAAGACTTGGAG CCCGAGCCCTCGGAGGGCGGGGATGTCCCCGAGCCTTGGGAGACCATTTCAGAGGAAGTGAATATCGCTGGAGACTCTCTCGGTCTGGCT CTGCCCCCACCACCGGCCTCCCCAGGATCTCGGACCAGCCCTCAGGAGCTGTCAGAGGAACTAAGCAGAAGGCTTCAGATCACTCCAGAC TCCAATGGGGAACAGTTCAGCTCTTTGATTCAAAGAGAACCCTCCTCAAGGTTGAGGTCATGCAGTGTCACCGACGCAGTTGCAGAACAG GGCCATCTACCACCGCCCAGTGCCCCAGCTGGGAGAGCGCGTTCATCAACTGTCACGGGTGGTGAGGAACCAACGCCATCAGTGGCCTAT GTACATACCACGCCGGGTCTGCCTTCAGGCTGGGAAGAAAGAAAAGATGCTAAGGGGCGCACATACTATGTCAATCATAACAATCGAACC ACAACTTGGACTCGACCTATCATGCAGCTTGCAGAAGATGGTGCGTCCGGATCAGCCACAAACAGTAACAACCATCTAATCGAGCCTCAG ATCCGCCGGCCTCGTAGCCTCAGCTCGCCAACAGTAACTTTATCTGCCCCGCTGGAGGGTGCCAAGGACTCACCCGTACGTCGGGCTGTG AAAGACACCCTTTCCAACCCACAGTCCCCACAGCCATCACCTTACAACTCCCCCAAACCACAACACAAAGTCACACAGAGCTTCTTGCCA CCCGGCTGGGAAATGAGGATAGCGCCAAACGGCCGGCCCTTCTTCATTGATCATAACACAAAGACTACAACCTGGGAAGATCCACGTTTG AAATTTCCAGTACATATGCGGTCAAAGACATCTTTAAACCCCAATGACCTTGGCCCCCTTCCTCCTGGCTGGGAAGAAAGAATTCACTTG GATGGCCGAACGTTTTATATTGATCATAATAGCAAAATTACTCAGTGGGAAGACCCAAGACTGCAGAACCCAGCTATTACTGGTCCGGCT GTCCCTTACTCCAGAGAATTTAAGCAGAAATATGACTACTTCAGGAAGAAATTAAAGAAACCTGCTGATATCCCCAATAGGTTTGAAATG AAACTTCACAGAAATAACATATTTGAAGAGTCCTATCGGAGAATTATGTCCGTGAAAAGACCAGATGTCCTAAAAGCTAGACTGTGGATT GAGTTTGAATCAGAGAAAGGTCTTGACTATGGGGGTGTGGCCAGAGAATGGTTCTTCTTACTGTCCAAAGAGATGTTCAACCCCTACTAC GGCCTCTTTGAGTACTCTGCCACGGACAACTACACCCTTCAGATCAACCCTAATTCAGGCCTCTGTAATGAGGATCATTTGTCCTACTTC ACTTTTATTGGAAGAGTTGCTGGTCTGGCCGTATTTCATGGGAAGCTCTTAGATGGTTTCTTCATTAGACCATTTTACAAGATGATGTTG GGAAAGCAGATAACCCTGAATGACATGGAATCTGTGGATAGTGAATATTACAACTCTTTGAAATGGATCCTGGAGAATGACCCTACTGAG CTGGACCTCATGTTCTGCATAGACGAAGAAAACTTTGGACAGACATATCAAGTGGATTTGAAGCCCAATGGGTCAGAAATAATGGTCACA AATGAAAACAAAAGGGAATATATCGACTTAGTCATCCAGTGGAGATTTGTGAACAGGGTCCAGAAGCAGATGAACGCCTTCTTGGAGGGA TTCACAGAACTACTTCCTATTGATTTGATTAAAATTTTTGATGAAAATGAGCTGGAGTTGCTCATGTGCGGCCTCGGTGATGTGGATGTG AATGACTGGAGACAGCATTCTATTTACAAGAACGGCTACTGCCCAAACCACCCCGTCATTCAGTGGTTCTGGAAGGCTGTGCTACTCATG GACGCCGAAAAGCGTATCCGGTTACTGCAGTTTGTCACAGGGACATCGCGAGTACCTATGAATGGATTTGCCGAACTTTATGGTTCCAAT GGTCCTCAGCTGTTTACAATAGAGCAATGGGGCAGTCCTGAGAAACTGCCCAGAGCTCACACATGCTTTAATCGCCTTGACTTACCTCCA TATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGCC TCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTGC AGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCCC ACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTTGTGCCTCTGCAGGCAAAGCCC TTAATAAATATTTTACATCCTTTCTAATGACAATGAATGGAATTAATCACTCAACAGGTATAGTATTACGACTCATGTTTACTTTTTAAA |
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FusionGenePPI for LUZP1_NEDD4L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LUZP1 | TADA2A, SP1, CUL5, YWHAB, LUZP4, C9orf41, C17orf59, DHCR24, HSPB1, MED4, PCM1, SCLT1, SSX2IP, OFD1, CEP170, KIAA0753, CEP104, CEP162, CEP290, CEP120, CEP152, CNTROB, SPICE1, CEP128, CEP135, CEP63, CEP89, CNTRL, NINL, NIN, ODF2, RPGRIP1L, DCTN1, DYNLT1, LCA5, POC1A, CAPZA2, CDK2, DBN1, FLNA, KIF11, MYH9, PPP1CB, IQGAP1, PDLIM7, ACTR2, SYNPO, MAPRE1, LIMA1, ANLN, MYO5C, MYO19, MYO18A, CDH1, CDC14A, KLHDC3, SCOC, MGME1, AARSD1, PLEC, AAK1, PPIP5K2, SEC24B, CCDC88A, EYA4, UBE2D2, TRIM25, G3BP1 | NEDD4L | SFN, NR3C1, ARHGDIA, SCNN1A, SCNN1B, SCNN1G, NEDD4L, AMOT, YWHAG, YWHAZ, PSMD4, YWHAB, TNK2, OCLN, APBB1, TOLLIP, NDFIP1, KCNB1, MAPKAPK3, CLIC2, EFEMP2, HGS, NDFIP2, MAP3K3, VDAC2, ZDHHC3, CAMK1D, RANBP10, CDK5, ABL1, MAGEB1, DMTN, AICDA, MARK2, KCNAB1, FKBP3, DAPK3, BRAF, MAP3K5, DDX54, ZAK, KCNAB3, NTRK1, CUEDC1, RPS6KB2, ABL2, CACNB1, YY1, MAP3K2, BBX, PRKX, ACVR1B, ADAP2, BMPR1A, AKT3, MINK1, AURKC, NSRP1, WIBG, SGK2, UBAC1, RPL30, MERTK, SRMS, SERPINF1, DYRK3, IFRD2, SCD, ROBO3, TRIM41, TMA16, TAF1B, SPAG8, STAC, H1F0, PRR16, KIFC3, RASL10B, PRRG1, CDK3, KCNAB2, FGF12, RNF7, APEX2, MRPL19, TGFB1I1, TBC1D7, NHP2, TMEM55A, CYP26B1, DECR2, SENP2, SIVA1, RASL11B, MAP2, STK40, NUDT16L1, C7orf50, TCEAL2, ZC3HAV1L, MOB3A, TARBP2, ZADH2, WBP2, ELAVL1, YWHAH, SGK1, RAF1, TSC22D3, WNK4, WNK1, IKBKB, SMAD7, AMOTL1, UBE2D2, UBC, SMAD2, SMAD3, YWHAQ, NPC2, MT2A, ATP1B1, CYBRD1, SLC7A7, PBX1, ACY3, HAX1, KIF3B, KCNH2, CAV3, UBE2L3, UBE2K, UBE2D1, UBE2E3, UBE2J2, CDC34, ARRDC3, ARRDC4, MED28, FBXL15, LAPTM5, RNF11, KCNQ1, SGK3, UBE2D3, NOTCH1, AATF, GORAB, UBE2N, HCN1, SMAD6, SLC9A3, SNCA, WNK3, PTCH1, DAZAP2, MOV10, CCDC8, FAM189B, PRRG3, TMEM51, TMEM171, SUSD6, FAM189A2, WBP1, ARRDC1, TMEM92, TMEM52B, LDLRAD4, XPO1, LITAF, SLC22A11, SLC22A8, RHOB, CRYAB, GRB10, KCNA3, ULK1, ERBB3, PTK2B, GRIA1, ILDR1, TNFAIP3, TNFRSF19, LPAR1, EDEM3, TRIM25, SCN5A, UBE2E1, UBE2E2, UBE2L6 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LUZP1_NEDD4L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LUZP1_NEDD4L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | NEDD4L | C0020538 | Hypertensive disease | 2 | CTD_human |
| Tgene | NEDD4L | C0008925 | Cleft Palate | 1 | CTD_human |
| Tgene | NEDD4L | C0014175 | Endometriosis | 1 | CTD_human |
| Tgene | NEDD4L | C0039075 | Syndactyly | 1 | CTD_human |
| Tgene | NEDD4L | C1868720 | Periventricular Nodular Heterotopia | 1 | CTD_human;ORPHANET |
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