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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 20355

FusionGeneSummary for LTA4H_SLC25A24

check button Fusion gene summary
Fusion gene informationFusion gene name: LTA4H_SLC25A24
Fusion gene ID: 20355
HgeneTgene
Gene symbol

LTA4H

SLC25A24

Gene ID

4048

29957

Gene nameleukotriene A4 hydrolasesolute carrier family 25 member 24
Synonyms-APC1|SCAMC-1|SCAMC1
Cytomap

12q23.1

1p13.3

Type of geneprotein-codingprotein-coding
Descriptionleukotriene A-4 hydrolaseLTA-4 hydrolasetesticular secretory protein Li 27calcium-binding mitochondrial carrier protein SCaMC-1calcium-binding transportermitochondrial ATP-Mg/Pi carrier protein 1mitochondrial Ca(2+)-dependent solute carrier protein 1short calcium-binding mitochondrial carrier 1small calcium-binding mitocho
Modification date2018052320180523
UniProtAcc

P09960

Q6NUK1

Ensembl transtripts involved in fusion geneENST00000228740, ENST00000552789, 
ENST00000413268, ENST00000548375, 
ENST00000565488, ENST00000370041, 
ENST00000569674, 
Fusion gene scores* DoF score6 X 5 X 3=902 X 2 X 2=8
# samples 62
** MAII scorelog2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: LTA4H [Title/Abstract] AND SLC25A24 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLTA4H

GO:0019370

leukotriene biosynthetic process

9774412|15078870

HgeneLTA4H

GO:0043171

peptide catabolic process

9774412|15078870|18804029


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSTADTCGA-BR-A4J6-01ALTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000228740ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000228740ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000228740ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000552789ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000413268ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-intronENST00000548375ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-

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FusionProtFeatures for LTA4H_SLC25A24


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LTA4H

P09960

SLC25A24

Q6NUK1

Epoxide hydrolase that catalyzes the final step in thebiosynthesis of the proinflammatory mediator leukotriene B4. Hasalso aminopeptidase activity. {ECO:0000269|PubMed:11917124,ECO:0000269|PubMed:12207002, ECO:0000269|PubMed:15078870,ECO:0000269|PubMed:18804029, ECO:0000269|PubMed:1897988,ECO:0000269|PubMed:1975494, ECO:0000269|PubMed:2244921}. Calcium-dependent mitochondrial solute carrier. Mediatesthe reversible, electroneutral exchange of Mg-ATP or Mg-ADPagainst phosphate ions, catalyzing the net uptake or efflux ofadenine nucleotides across the mitochondrial inner membrane.Nucleotide transport is inactive when cytosolic calcium levels arelow, and is activated by an increase in cytosolic calcium levels.May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation ofcalcium-phosphate precipitates in the mitochondrial matrix, andthereby buffering calcium levels in the mitochondrial matrix.{ECO:0000269|PubMed:15123600, ECO:0000269|PubMed:22015608}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519135_137478612RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519267_272478612RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518135_137454489RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518267_272454489RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519135_137454588RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519267_272454588RegionSubstrate binding
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610383_471291459RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610383_471310478RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610310_345291459Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610366_388291459Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610407_445291459Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610466_477291459Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610310_345310478Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610366_388310478Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610407_445310478Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610466_477310478Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610296_309291459TransmembraneHelical%3B Name%3D3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610346_365291459TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610389_406291459TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610446_465291459TransmembraneHelical%3B Name%3D6
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610346_365310478TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610389_406310478TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610446_465310478TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519564_566478612RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518564_566454489RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519564_566454588RegionSubstrate binding
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610135_146291459Calcium bindingNote=4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61032_43291459Calcium bindingNote=1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61068_79291459Calcium bindingNote=2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61099_110291459Calcium bindingNote=3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610135_146310478Calcium bindingNote=4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61032_43310478Calcium bindingNote=1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61068_79310478Calcium bindingNote=2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61099_110310478Calcium bindingNote=3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610122_157291459DomainEF-hand 4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61019_54291459DomainEF-hand 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61055_88291459DomainEF-hand 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-61086_121291459DomainEF-hand 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610122_157310478DomainEF-hand 4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61019_54310478DomainEF-hand 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61055_88310478DomainEF-hand 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-61086_121310478DomainEF-hand 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610192_278291459RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610286_371291459RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610192_278310478RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610286_371310478RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-6101_197291459Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610216_252291459Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610273_295291459Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-6101_197310478Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610216_252310478Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610273_295310478Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610198_215291459TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041-610253_272291459TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610198_215310478TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610253_272310478TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488-610296_309310478TransmembraneHelical%3B Name%3D3


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FusionGeneSequence for LTA4H_SLC25A24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_646aa
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_646aa
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_622aa
MLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSS
ALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIA
LVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVI
AHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPY
EKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQ
RWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSS

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_622aa
MLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSS
ALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIA
LVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVI
AHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPY
EKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQ
RWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_1938nt
ATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCCGGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTT
ACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGTCCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTT
ACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCT
CTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACT
CCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACT
CCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCT
GACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTA
GAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCT
ATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGC
ATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCAT
AGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGC
GGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACA
CATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTA
CTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATA
ACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTAC
TCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATG
AAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCT
TTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGG
CTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCC
AGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGA
CGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTAT

>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_1938nt
ATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCCGGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTT
ACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGTCCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTT
ACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCT
CTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACT
CCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACT
CCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCT
GACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTA
GAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCT
ATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGC
ATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCAT
AGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGC
GGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACA
CATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTA
CTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATA
ACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTAC
TCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATG
AAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCT
TTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGG
CTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCC
AGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGA
CGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTAT

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_1866nt
ATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCAGCCTTAAAGGTT
TTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAAAGTTACAAGGGA
TCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCTCCAAAATCTTCT
GCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCACTGCAGAGCAATC
CTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTTATGAGTGCTATT
CGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGCTACCTGATTGCT
TTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAG
TTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTGGTCCTGCCACCA
TCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTCTCCAATGTCATT
GCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGACATACTGTGTAC
TTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTACAGAATTCGGTA
AAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCTTCAGTTCCCTAT
GAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAG
TTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTCAATCAAGTTGAT
TGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATTGCCTTAAGTCAA
AGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAA
CATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTTGCTGTGTATGAG
CTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGC
ACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCCCCACAGCTGAAT
ATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCT

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_1866nt
ATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCAGCCTTAAAGGTT
TTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAAAGTTACAAGGGA
TCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCTCCAAAATCTTCT
GCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCACTGCAGAGCAATC
CTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTTATGAGTGCTATT
CGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGCTACCTGATTGCT
TTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAG
TTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTGGTCCTGCCACCA
TCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTCTCCAATGTCATT
GCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGACATACTGTGTAC
TTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTACAGAATTCGGTA
AAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCTTCAGTTCCCTAT
GAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAG
TTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTCAATCAAGTTGAT
TGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATTGCCTTAAGTCAA
AGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAGAAGATTTTGAAA
CATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTTGCTGTGTATGAG
CTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGTGCCTTATCCAGC
ACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCCCCACAGCTGAAT
ATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATGAAGGTGCTCCCT


* Fusion transcript sequences (Full-length transcript).
>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_4697nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT
ACTTACAGTTTCTATCAAAAATATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCA
GTTTCCTAATTGAAAAAAAAAAATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATC
ATGCTTTTTACAGCTGGCTCCATGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTT
TGACACAAGGTGATATTTTTTGTGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCC
AGAGCCTCAGGATTGGCCAGGCTCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGT
AAGTAATTTTTTAAAATTTCATAATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTC
AACTCCAATACTATCCAGACTTCAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCT
GTAGCAGACACTGGCAGTTCCCTGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTC
CTCTGTTCTCAGGGAATCTTTGTTAGAAAAATGCTGCCATATTTGTTTCTCACCTATTAGTCTTGTCTCCCAGTCAAGAGAATAAATTTA

>In-frame_LTA4H_ENST00000228740_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_3910nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000565488_chr1_108686332_-_4585nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT
ATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCAGTTTCCTAATTGAAAAAAAAAA
ATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATCATGCTTTTTACAGCTGGCTCCA
TGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTTTGACACAAGGTGATATTTTTTG
TGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCCAGAGCCTCAGGATTGGCCAGGC
TCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGTAAGTAATTTTTTAAAATTTCAT
AATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTCAACTCCAATACTATCCAGACTT
CAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCTGTAGCAGACACTGGCAGTTCCC
TGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTCCTCTGTTCTCAGGGAATCTTTG

>In-frame_LTA4H_ENST00000552789_chr12_96402872_-_SLC25A24_ENST00000370041_chr1_108686332_-_3798nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT


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FusionGenePPI for LTA4H_SLC25A24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
LTA4HGH1, MCC, TMEM62, DDA1, UBA5, HDAC5, ELAVL1, SIRT7, TINF2, SIRT1, ZNF593, ALDOA, FKBP2, GALK2, IDH1, PGM1, PRPF4, SPR, TRAP1, NAPRT, TAGLN2, NTRK1, KRASSLC25A24HNRNPM, FAF2, FLOT1, MPV17, CD55, FBXO6, PARK2, BSG, TMEM171, LPAR6, SCN2B, SLC25A4, SLC25A5, SLC25A6, CHMP4B, NDUFA4, COQ9, APLNR, TMEM108, SLC39A9, SLC1A5, SLC15A1, MFSD4, SLC22A6, SLC2A12, ACVRL1, TOMM22, C1orf85, GYG2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LTA4H_SLC25A24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneLTA4HP09960DB01197CaptoprilLeukotriene A-4 hydrolasesmall moleculeapproved

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RelatedDiseases for LTA4H_SLC25A24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLTA4HC0004153Atherosclerosis1CTD_human
HgeneLTA4HC0011570Mental Depression1PSYGENET
HgeneLTA4HC0011581Depressive disorder1PSYGENET
HgeneLTA4HC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneSLC25A24C0023893Liver Cirrhosis, Experimental1CTD_human