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Fusion gene ID: 19888 |
FusionGeneSummary for LMCD1_PBX3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LMCD1_PBX3 | Fusion gene ID: 19888 | Hgene | Tgene | Gene symbol | LMCD1 | PBX3 | Gene ID | 29995 | 5090 |
| Gene name | LIM and cysteine rich domains 1 | PBX homeobox 3 | |
| Synonyms | - | - | |
| Cytomap | 3p25.3 | 9q33.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | LIM and cysteine-rich domains protein 1dyxin | pre-B-cell leukemia transcription factor 3homeobox protein PBX3pre-B-cell leukemia homeobox 3 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9NZU5 | P40426 | |
| Ensembl transtripts involved in fusion gene | ENST00000157600, ENST00000535732, ENST00000454244, ENST00000397386, | ENST00000342287, ENST00000373487, ENST00000373489, ENST00000373483, ENST00000447726, ENST00000538998, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 7 X 4 X 5=140 |
| # samples | 3 | 8 | |
| ** MAII score | log2(3/8*10)=1.90689059560852 | log2(8/140*10)=-0.807354922057604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LMCD1 [Title/Abstract] AND PBX3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Transcription factor involved fusion gene, inframe and retained DNA-binding domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA020849 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + | ||
| ChiTaRS3.1 | DA020867 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000157600 | ENST00000342287 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| In-frame | ENST00000157600 | ENST00000373487 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| In-frame | ENST00000157600 | ENST00000373489 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-5UTR | ENST00000157600 | ENST00000373483 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-5UTR | ENST00000157600 | ENST00000447726 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-3UTR | ENST00000157600 | ENST00000538998 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| In-frame | ENST00000535732 | ENST00000342287 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| In-frame | ENST00000535732 | ENST00000373487 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| In-frame | ENST00000535732 | ENST00000373489 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-5UTR | ENST00000535732 | ENST00000373483 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-5UTR | ENST00000535732 | ENST00000447726 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5CDS-3UTR | ENST00000535732 | ENST00000538998 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000454244 | ENST00000342287 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000454244 | ENST00000373487 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000454244 | ENST00000373489 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-5UTR | ENST00000454244 | ENST00000373483 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-5UTR | ENST00000454244 | ENST00000447726 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3UTR | ENST00000454244 | ENST00000538998 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000397386 | ENST00000342287 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000397386 | ENST00000373487 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3CDS | ENST00000397386 | ENST00000373489 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-5UTR | ENST00000397386 | ENST00000373483 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-5UTR | ENST00000397386 | ENST00000447726 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
| 5UTR-3UTR | ENST00000397386 | ENST00000538998 | LMCD1 | chr3 | 8543667 | + | PBX3 | chr9 | 128691932 | + |
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FusionProtFeatures for LMCD1_PBX3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LMCD1 | PBX3 |
| Transcriptional cofactor that restricts GATA6 functionby inhibiting DNA-binding, resulting in repression of GATA6transcriptional activation of downstream target genes. RepressesGATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to thecTNC promoter (By similarity). Plays a critical role in thedevelopment of cardiac hypertrophy via activation ofcalcineurin/nuclear factor of activated T-cells signaling pathway.{ECO:0000250, ECO:0000269|PubMed:20026769}. | Transcriptional activator that binds the sequence 5'-ATCAATCAA-3'. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000373483 | + | 1 | 8 | 130_138 | -9 | 254 | Compositional bias | Note=Poly-Ala |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000447726 | + | 2 | 9 | 130_138 | 97 | 360 | Compositional bias | Note=Poly-Ala |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000342287 | + | 2 | 8 | 235_297 | 172 | 764 | DNA binding | Homeobox%3B TALE-type |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000373483 | + | 1 | 8 | 235_297 | -9 | 254 | DNA binding | Homeobox%3B TALE-type |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000373489 | + | 2 | 9 | 235_297 | 172 | 435 | DNA binding | Homeobox%3B TALE-type |
| Tgene | >PBX3 | chr3:8543667 | chr9:128691932 | ENST00000447726 | + | 2 | 9 | 235_297 | 97 | 360 | DNA binding | Homeobox%3B TALE-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >LMCD1 | chr3:8543667 | chr9:128691932 | ENST00000157600 | + | 1 | 6 | 28_58 | 14 | 366 | Compositional bias | Note=Cys-rich |
| Hgene | >LMCD1 | chr3:8543667 | chr9:128691932 | ENST00000157600 | + | 1 | 6 | 241_306 | 14 | 366 | Domain | LIM zinc-binding 1 |
| Hgene | >LMCD1 | chr3:8543667 | chr9:128691932 | ENST00000157600 | + | 1 | 6 | 307_365 | 14 | 366 | Domain | LIM zinc-binding 2 |
| Hgene | >LMCD1 | chr3:8543667 | chr9:128691932 | ENST00000157600 | + | 1 | 6 | 99_206 | 14 | 366 | Domain | PET |
| Tgene | PBX3 | chr3:8543667 | chr9:128691932 | ENST00000342287 | + | 2 | 8 | 130_138 | 172 | 764 | Compositional bias | Note=Poly-Ala |
| Tgene | PBX3 | chr3:8543667 | chr9:128691932 | ENST00000373489 | + | 2 | 9 | 130_138 | 172 | 435 | Compositional bias | Note=Poly-Ala |
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FusionGeneSequence for LMCD1_PBX3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_194aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGG >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_298aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPTSVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAH AVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANG >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_277aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGS SGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSV >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_194aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGG >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_298aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQSLVKDPKERGSKGSDIQPTSVVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAH AVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANG >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_277aa MAKVAKDLNPGVKKACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATE ILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGS SGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_582nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCT GCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTGGA >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_894nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGAGTCTTGTAAAGGATCCAAAAGAAAGAGGGAGCAAAGGTTCTGACATCCAGCCAACTAGCGTGGTATCCAATTGGTTTGGC AACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACAC GCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCT GGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGAGCCAATGTGCAATCACAGGTGGATACC CTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGA >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_831nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCT GCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCT TCTGGTTCTTTTAACCTCCCAAATTCTGGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGA GCCAATGTGCAATCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTAC AGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCTCCTACAGAAGGCCCAGGAAGTGTG >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_582nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCT GCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTGGA >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_894nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGAGTCTTGTAAAGGATCCAAAAGAAAGAGGGAGCAAAGGTTCTGACATCCAGCCAACTAGCGTGGTATCCAATTGGTTTGGC AACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACAC GCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCT GGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGAGCCAATGTGCAATCACAGGTGGATACC CTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGA >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_831nt ATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAG AGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAA CAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAA ATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACA GTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCT GCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCT TCTGGTTCTTTTAACCTCCCAAATTCTGGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGA GCCAATGTGCAATCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTAC AGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCTCCTACAGAAGGCCCAGGAAGTGTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_2404nt GGACAGCCTCGCGCTGGGATTGGCTGGCCTCGCGCGAGCGCCGGCGCGGAGTGGCTGGCGAGGTTTTAGAGGGAGTCCCGCTCTCCAATT AAAGCGGCCCAGCTGCGCCTGGCTGCGCACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGC CCTCGCGCCTCTGCCTGAGAAGCCAGGCGCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAA AAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAG AATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAG GTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCC CTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAAT CAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGC AGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACA GTGATGGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGA CTTCTCCTACAGAAGGCCCAGGAAGTGTGCACTCGGATACCTCTAACTAATCTCTGGCCACACTTTTCCCTGAGCTACATGCCTTGATAA GTGCATTCAGAGCAATAGGAGGAAAAGGAAAGCGTTTTTGTAGCCCACCATCTACAGCTTTACTGTAAAACCTTGTCTTATTCGAGAACT TGGTAAATCTGTTTTTTAAGGAATCATAATCATTTGTATTTATACTTAAAAACACACAATGTTAAAAAAAATAAAGCACTTTATCCAATT AGGCCAAGATTTAACATTGTTGACAGTCCTGTAGCTATTTTATCATAATTTATTATCAATATTTTACATTAATGGTTTCACAGTTGCCAA TTACTTGGCCTTAAGGGTAAAAAGTACAATATACACTAAACCTCAACCGTTAAAGCAGATGCAAAAATTCACCTCACCTAAATTGAACTT CTTGCATATTTCCATTACTGACTTGGATTGTCTTTCTTTCATATCACTAATGGAGTTGGAATAAAGAGCTGTTTGCCTATCCCTGTTAAT GATGGTTGTGTTTAAGAATCTTCCTCGTCACGTTTGTGTTCAGATCTCTTATGTTATAATTAGATCAGAGACTGGTAGCATCGTTTCTCT CTCTGAAAGCACCAGTGCCCAGAGTCTGCTCGGTAATAAAATTATGGATCCAGATTGTTCTGAGAGACGAAGATACTTGCTGCTGATAGA GGTGAAAACGAGATTGATCCGTCTGGGGTTTTACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAGGTTTGCTACGTCCTCTGGGCATC TGCAAAAGGCCCTGCTCTCTGGAGTGTTGTATATAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCT CATGCGAACTCATACAAACCAATAGAATTTCAACATGTTCTGTAGCTTAGAGTGCTCACTTACTACCTCTGAACAATACTCACGCTGTAG TTTGTCTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGTTTCCCTTCATAAAATGTAATGTACATTGTAATCTTTTAAAAGAAA AATCAGGGTTGCACTTGCAACTTTTAAAAAACCGAGTGTGGAAACATTGGGTCTTAATTCAACACAGGATCGGTAAAACTGTTGTAAATA CTGAGAAACATTTTGAATGTTCTTCATCTTATTACTAATCCATGCAAAAAAAAAAAAAAAAGCAGCGACTAATTGTGATGCATTCAGATT TCAGTATTCAGTACTGTATATTTCACCCTGTGTAATGGGGCCCCCTCTCCTTTCTCTCTTTTTGTATTGTATGCGATTCTGAAACTGATT GAGTCATGAAAATAATTTGTGGCGGTGATTCTAATGTATTAAAAACGTTTCGTGTTCCTTTCTAACTGGATTACACCCTGGATTGAAAAA >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_2580nt GGACAGCCTCGCGCTGGGATTGGCTGGCCTCGCGCGAGCGCCGGCGCGGAGTGGCTGGCGAGGTTTTAGAGGGAGTCCCGCTCTCCAATT AAAGCGGCCCAGCTGCGCCTGGCTGCGCACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGC CCTCGCGCCTCTGCCTGAGAAGCCAGGCGCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAA AAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAG AATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAG GTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCC CTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTGTCACAGAGTCTTGTAAAGGATCCAAAAGAAAGAGG GAGCAAAGGTTCTGACATCCAGCCAACTAGCGTGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTT TCAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTC GCCCACCACACCAAATTCCGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCTGGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGA TTCTTACCAAGGGTCCCAAGTCGGAGCCAATGTGCAATCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGA TGGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTC TCCTACAGAAGGCCCAGGAAGTGTGCACTCGGATACCTCTAACTAATCTCTGGCCACACTTTTCCCTGAGCTACATGCCTTGATAAGTGC ATTCAGAGCAATAGGAGGAAAAGGAAAGCGTTTTTGTAGCCCACCATCTACAGCTTTACTGTAAAACCTTGTCTTATTCGAGAACTTGGT AAATCTGTTTTTTAAGGAATCATAATCATTTGTATTTATACTTAAAAACACACAATGTTAAAAAAAATAAAGCACTTTATCCAATTAGGC CAAGATTTAACATTGTTGACAGTCCTGTAGCTATTTTATCATAATTTATTATCAATATTTTACATTAATGGTTTCACAGTTGCCAATTAC TTGGCCTTAAGGGTAAAAAGTACAATATACACTAAACCTCAACCGTTAAAGCAGATGCAAAAATTCACCTCACCTAAATTGAACTTCTTG CATATTTCCATTACTGACTTGGATTGTCTTTCTTTCATATCACTAATGGAGTTGGAATAAAGAGCTGTTTGCCTATCCCTGTTAATGATG GTTGTGTTTAAGAATCTTCCTCGTCACGTTTGTGTTCAGATCTCTTATGTTATAATTAGATCAGAGACTGGTAGCATCGTTTCTCTCTCT GAAAGCACCAGTGCCCAGAGTCTGCTCGGTAATAAAATTATGGATCCAGATTGTTCTGAGAGACGAAGATACTTGCTGCTGATAGAGGTG AAAACGAGATTGATCCGTCTGGGGTTTTACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAGGTTTGCTACGTCCTCTGGGCATCTGCA AAAGGCCCTGCTCTCTGGAGTGTTGTATATAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATG CGAACTCATACAAACCAATAGAATTTCAACATGTTCTGTAGCTTAGAGTGCTCACTTACTACCTCTGAACAATACTCACGCTGTAGTTTG TCTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGTTTCCCTTCATAAAATGTAATGTACATTGTAATCTTTTAAAAGAAAAATC AGGGTTGCACTTGCAACTTTTAAAAAACCGAGTGTGGAAACATTGGGTCTTAATTCAACACAGGATCGGTAAAACTGTTGTAAATACTGA GAAACATTTTGAATGTTCTTCATCTTATTACTAATCCATGCAAAAAAAAAAAAAAAAGCAGCGACTAATTGTGATGCATTCAGATTTCAG TATTCAGTACTGTATATTTCACCCTGTGTAATGGGGCCCCCTCTCCTTTCTCTCTTTTTGTATTGTATGCGATTCTGAAACTGATTGAGT CATGAAAATAATTTGTGGCGGTGATTCTAATGTATTAAAAACGTTTCGTGTTCCTTTCTAACTGGATTACACCCTGGATTGAAAAAGTCT >In-frame_LMCD1_ENST00000157600_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_2244nt GGACAGCCTCGCGCTGGGATTGGCTGGCCTCGCGCGAGCGCCGGCGCGGAGTGGCTGGCGAGGTTTTAGAGGGAGTCCCGCTCTCCAATT AAAGCGGCCCAGCTGCGCCTGGCTGCGCACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGC CCTCGCGCCTCTGCCTGAGAAGCCAGGCGCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAA AAAGGCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAG AATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAG GTTCCTTGATGCCAGACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCC CTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAAT CAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGC AGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCTGGGGACATGTT CATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGAGCCAATGTGCAATCACAGGTGGATACCCTCCGTCATGT TATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGA CGCAACAACTCCATCTTCTGTGACTTCTCCTACAGAAGGCCCAGGAAGTGTGCACTCGGATACCTCTAACTAATCTCTGGCCACACTTTT CCCTGAGCTACATGCCTTGATAAGTGCATTCAGAGCAATAGGAGGAAAAGGAAAGCGTTTTTGTAGCCCACCATCTACAGCTTTACTGTA AAACCTTGTCTTATTCGAGAACTTGGTAAATCTGTTTTTTAAGGAATCATAATCATTTGTATTTATACTTAAAAACACACAATGTTAAAA AAAATAAAGCACTTTATCCAATTAGGCCAAGATTTAACATTGTTGACAGTCCTGTAGCTATTTTATCATAATTTATTATCAATATTTTAC ATTAATGGTTTCACAGTTGCCAATTACTTGGCCTTAAGGGTAAAAAGTACAATATACACTAAACCTCAACCGTTAAAGCAGATGCAAAAA TTCACCTCACCTAAATTGAACTTCTTGCATATTTCCATTACTGACTTGGATTGTCTTTCTTTCATATCACTAATGGAGTTGGAATAAAGA GCTGTTTGCCTATCCCTGTTAATGATGGTTGTGTTTAAGAATCTTCCTCGTCACGTTTGTGTTCAGATCTCTTATGTTATAATTAGATCA GAGACTGGTAGCATCGTTTCTCTCTCTGAAAGCACCAGTGCCCAGAGTCTGCTCGGTAATAAAATTATGGATCCAGATTGTTCTGAGAGA CGAAGATACTTGCTGCTGATAGAGGTGAAAACGAGATTGATCCGTCTGGGGTTTTACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAG GTTTGCTACGTCCTCTGGGCATCTGCAAAAGGCCCTGCTCTCTGGAGTGTTGTATATAGTGTAGCAAAAGAGTATTTATACATCCCACCA ATCAAAACACAGCTTTATTACCTCATGCGAACTCATACAAACCAATAGAATTTCAACATGTTCTGTAGCTTAGAGTGCTCACTTACTACC TCTGAACAATACTCACGCTGTAGTTTGTCTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGTTTCCCTTCATAAAATGTAATGT ACATTGTAATCTTTTAAAAGAAAAATCAGGGTTGCACTTGCAACTTTTAAAAAACCGAGTGTGGAAACATTGGGTCTTAATTCAACACAG >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000342287_chr9_128691932_+_2286nt ACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGCCCTCGCGCCTCTGCCTGAGAAGCCAGGC GCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACAT GTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTT AGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGT AACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAG CTGGCCAAGAAATGCAGCATCACAGTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTT CAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCG CCCACCACACCAAATTCCGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTA CAGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCTCCTACAGAAGGCCCAGGAAGTGT GCACTCGGATACCTCTAACTAATCTCTGGCCACACTTTTCCCTGAGCTACATGCCTTGATAAGTGCATTCAGAGCAATAGGAGGAAAAGG AAAGCGTTTTTGTAGCCCACCATCTACAGCTTTACTGTAAAACCTTGTCTTATTCGAGAACTTGGTAAATCTGTTTTTTAAGGAATCATA ATCATTTGTATTTATACTTAAAAACACACAATGTTAAAAAAAATAAAGCACTTTATCCAATTAGGCCAAGATTTAACATTGTTGACAGTC CTGTAGCTATTTTATCATAATTTATTATCAATATTTTACATTAATGGTTTCACAGTTGCCAATTACTTGGCCTTAAGGGTAAAAAGTACA ATATACACTAAACCTCAACCGTTAAAGCAGATGCAAAAATTCACCTCACCTAAATTGAACTTCTTGCATATTTCCATTACTGACTTGGAT TGTCTTTCTTTCATATCACTAATGGAGTTGGAATAAAGAGCTGTTTGCCTATCCCTGTTAATGATGGTTGTGTTTAAGAATCTTCCTCGT CACGTTTGTGTTCAGATCTCTTATGTTATAATTAGATCAGAGACTGGTAGCATCGTTTCTCTCTCTGAAAGCACCAGTGCCCAGAGTCTG CTCGGTAATAAAATTATGGATCCAGATTGTTCTGAGAGACGAAGATACTTGCTGCTGATAGAGGTGAAAACGAGATTGATCCGTCTGGGG TTTTACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAGGTTTGCTACGTCCTCTGGGCATCTGCAAAAGGCCCTGCTCTCTGGAGTGTT GTATATAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATGCGAACTCATACAAACCAATAGAAT TTCAACATGTTCTGTAGCTTAGAGTGCTCACTTACTACCTCTGAACAATACTCACGCTGTAGTTTGTCTCTTTCTTATCTTTTTGCATCT TGTAATTAACTCTTTGTTTCCCTTCATAAAATGTAATGTACATTGTAATCTTTTAAAAGAAAAATCAGGGTTGCACTTGCAACTTTTAAA AAACCGAGTGTGGAAACATTGGGTCTTAATTCAACACAGGATCGGTAAAACTGTTGTAAATACTGAGAAACATTTTGAATGTTCTTCATC TTATTACTAATCCATGCAAAAAAAAAAAAAAAAGCAGCGACTAATTGTGATGCATTCAGATTTCAGTATTCAGTACTGTATATTTCACCC TGTGTAATGGGGCCCCCTCTCCTTTCTCTCTTTTTGTATTGTATGCGATTCTGAAACTGATTGAGTCATGAAAATAATTTGTGGCGGTGA TTCTAATGTATTAAAAACGTTTCGTGTTCCTTTCTAACTGGATTACACCCTGGATTGAAAAAGTCTTCCTCGTGGTAGTTATATGTAGTT >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373487_chr9_128691932_+_2462nt ACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGCCCTCGCGCCTCTGCCTGAGAAGCCAGGC GCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACAT GTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTT AGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGT AACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAG CTGGCCAAGAAATGCAGCATCACAGTGTCACAGAGTCTTGTAAAGGATCCAAAAGAAAGAGGGAGCAAAGGTTCTGACATCCAGCCAACT AGCGTGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTTCAGGAAGAAGCCAACCTCTATGCTGCA AAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCGCCCACCACACCAAATTCCGGTTCTTCT GGTTCTTTTAACCTCCCAAATTCTGGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGAGCC AATGTGCAATCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGATGGCCTTGGAGGAAATTCACTGTACAGT CCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCTCCTACAGAAGGCCCAGGAAGTGTGCAC TCGGATACCTCTAACTAATCTCTGGCCACACTTTTCCCTGAGCTACATGCCTTGATAAGTGCATTCAGAGCAATAGGAGGAAAAGGAAAG CGTTTTTGTAGCCCACCATCTACAGCTTTACTGTAAAACCTTGTCTTATTCGAGAACTTGGTAAATCTGTTTTTTAAGGAATCATAATCA TTTGTATTTATACTTAAAAACACACAATGTTAAAAAAAATAAAGCACTTTATCCAATTAGGCCAAGATTTAACATTGTTGACAGTCCTGT AGCTATTTTATCATAATTTATTATCAATATTTTACATTAATGGTTTCACAGTTGCCAATTACTTGGCCTTAAGGGTAAAAAGTACAATAT ACACTAAACCTCAACCGTTAAAGCAGATGCAAAAATTCACCTCACCTAAATTGAACTTCTTGCATATTTCCATTACTGACTTGGATTGTC TTTCTTTCATATCACTAATGGAGTTGGAATAAAGAGCTGTTTGCCTATCCCTGTTAATGATGGTTGTGTTTAAGAATCTTCCTCGTCACG TTTGTGTTCAGATCTCTTATGTTATAATTAGATCAGAGACTGGTAGCATCGTTTCTCTCTCTGAAAGCACCAGTGCCCAGAGTCTGCTCG GTAATAAAATTATGGATCCAGATTGTTCTGAGAGACGAAGATACTTGCTGCTGATAGAGGTGAAAACGAGATTGATCCGTCTGGGGTTTT ACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAGGTTTGCTACGTCCTCTGGGCATCTGCAAAAGGCCCTGCTCTCTGGAGTGTTGTAT ATAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATGCGAACTCATACAAACCAATAGAATTTCA ACATGTTCTGTAGCTTAGAGTGCTCACTTACTACCTCTGAACAATACTCACGCTGTAGTTTGTCTCTTTCTTATCTTTTTGCATCTTGTA ATTAACTCTTTGTTTCCCTTCATAAAATGTAATGTACATTGTAATCTTTTAAAAGAAAAATCAGGGTTGCACTTGCAACTTTTAAAAAAC CGAGTGTGGAAACATTGGGTCTTAATTCAACACAGGATCGGTAAAACTGTTGTAAATACTGAGAAACATTTTGAATGTTCTTCATCTTAT TACTAATCCATGCAAAAAAAAAAAAAAAAGCAGCGACTAATTGTGATGCATTCAGATTTCAGTATTCAGTACTGTATATTTCACCCTGTG TAATGGGGCCCCCTCTCCTTTCTCTCTTTTTGTATTGTATGCGATTCTGAAACTGATTGAGTCATGAAAATAATTTGTGGCGGTGATTCT AATGTATTAAAAACGTTTCGTGTTCCTTTCTAACTGGATTACACCCTGGATTGAAAAAGTCTTCCTCGTGGTAGTTATATGTAGTTTCAA >In-frame_LMCD1_ENST00000535732_chr3_8543667_+_PBX3_ENST00000373489_chr9_128691932_+_2126nt ACAGAGCTCCCTCCCAGGCCCGCGAACTTGGCCATTCAGCCGCCGCTGTCCCCGCTGCGCGCCCTCGCGCCTCTGCCTGAGAAGCCAGGC GCTGTTCCCCCACCCCAGAAGAGGATGGCAAAGGTGGCTAAGGACCTCAACCCAGGAGTTAAAAAGGCATGTAATGAATTTACTACACAT GTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTT AGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGT AACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAG CTGGCCAAGAAATGCAGCATCACAGTGTCACAGGTATCCAATTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATTGGCAAGTTT CAGGAAGAAGCCAACCTCTATGCTGCAAAGACGGCCGTGACAGCTGCACACGCAGTAGCAGCAGCTGTGCAGAACAACCAGACCAATTCG CCCACCACACCAAATTCCGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCTGGGGACATGTTCATGAACATGCAGAGTCTGAATGGGGAT TCTTACCAAGGGTCCCAAGTCGGAGCCAATGTGCAATCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGAT GGCCTTGGAGGAAATTCACTGTACAGTCCACATAATTTAAATGCTAATGGAGGCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCT CCTACAGAAGGCCCAGGAAGTGTGCACTCGGATACCTCTAACTAATCTCTGGCCACACTTTTCCCTGAGCTACATGCCTTGATAAGTGCA TTCAGAGCAATAGGAGGAAAAGGAAAGCGTTTTTGTAGCCCACCATCTACAGCTTTACTGTAAAACCTTGTCTTATTCGAGAACTTGGTA AATCTGTTTTTTAAGGAATCATAATCATTTGTATTTATACTTAAAAACACACAATGTTAAAAAAAATAAAGCACTTTATCCAATTAGGCC AAGATTTAACATTGTTGACAGTCCTGTAGCTATTTTATCATAATTTATTATCAATATTTTACATTAATGGTTTCACAGTTGCCAATTACT TGGCCTTAAGGGTAAAAAGTACAATATACACTAAACCTCAACCGTTAAAGCAGATGCAAAAATTCACCTCACCTAAATTGAACTTCTTGC ATATTTCCATTACTGACTTGGATTGTCTTTCTTTCATATCACTAATGGAGTTGGAATAAAGAGCTGTTTGCCTATCCCTGTTAATGATGG TTGTGTTTAAGAATCTTCCTCGTCACGTTTGTGTTCAGATCTCTTATGTTATAATTAGATCAGAGACTGGTAGCATCGTTTCTCTCTCTG AAAGCACCAGTGCCCAGAGTCTGCTCGGTAATAAAATTATGGATCCAGATTGTTCTGAGAGACGAAGATACTTGCTGCTGATAGAGGTGA AAACGAGATTGATCCGTCTGGGGTTTTACGGTGTGCACTGGGTGCTGCACAGACTTGTCAAGGTTTGCTACGTCCTCTGGGCATCTGCAA AAGGCCCTGCTCTCTGGAGTGTTGTATATAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATGC GAACTCATACAAACCAATAGAATTTCAACATGTTCTGTAGCTTAGAGTGCTCACTTACTACCTCTGAACAATACTCACGCTGTAGTTTGT CTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGTTTCCCTTCATAAAATGTAATGTACATTGTAATCTTTTAAAAGAAAAATCA GGGTTGCACTTGCAACTTTTAAAAAACCGAGTGTGGAAACATTGGGTCTTAATTCAACACAGGATCGGTAAAACTGTTGTAAATACTGAG 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FusionGenePPI for LMCD1_PBX3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LMCD1 | IKBKG, PRKAG3, APP, NKX3-1, FBXO25, TRIM63, TRIM55, SCLT1 | PBX3 | AGTRAP, HOXA9, HOXB8, ZNHIT3, RABAC1, MAGEA1, TPM3, TRAF1, ARL6IP1, MAGEC2, TRIM44, MAL2, FSD2, LMX1B, MAB21L1, MEIS2, MAB21L2, PTEN, FOXE1, FAM222A, C5orf24, C16orf71, VWA5A, CCDC120, TMOD3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LMCD1_PBX3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LMCD1_PBX3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | LMCD1 | C0026266 | Mitral Valve Insufficiency | 1 | CTD_human |
| Hgene | LMCD1 | C0026267 | Mitral Valve Prolapse Syndrome | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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