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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 19880

FusionGeneSummary for LMBRD1_LGSN

check button Fusion gene summary
Fusion gene informationFusion gene name: LMBRD1_LGSN
Fusion gene ID: 19880
HgeneTgene
Gene symbol

LMBRD1

LGSN

Gene ID

55788

51557

Gene nameLMBR1 domain containing 1lengsin, lens protein with glutamine synthetase domain
SynonymsC6orf209|LMBD1|MAHCF|NESIGLULD1|LGS
Cytomap

6q13

6q12

Type of geneprotein-codingprotein-coding
Descriptionprobable lysosomal cobalamin transporterHDAg-L-interacting protein NESIhepatitis delta antigen-L interacting proteinliver regeneration p-53 related proteinnuclear export signal-interacting proteinlengsinglutamate-ammonia ligase (glutamine synthase) domain containing 1glutamate-ammonia ligase domain-containing protein 1
Modification date2018052220180523
UniProtAcc

Q9NUN5

Q5TDP6

Ensembl transtripts involved in fusion geneENST00000370577, ENST00000370570, 
ENST00000370658, ENST00000370657, 
Fusion gene scores* DoF score5 X 4 X 5=1001 X 1 X 1=1
# samples 51
** MAII scorelog2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: LMBRD1 [Title/Abstract] AND LGSN [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVTHCATCGA-FE-A239-01ALMBRD1chr6

70428848

-LGSNchr6

64004950

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000370577ENST00000370658LMBRD1chr6

70428848

-LGSNchr6

64004950

-
In-frameENST00000370577ENST00000370657LMBRD1chr6

70428848

-LGSNchr6

64004950

-
In-frameENST00000370570ENST00000370658LMBRD1chr6

70428848

-LGSNchr6

64004950

-
In-frameENST00000370570ENST00000370657LMBRD1chr6

70428848

-LGSNchr6

64004950

-

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FusionProtFeatures for LMBRD1_LGSN


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LMBRD1

Q9NUN5

LGSN

Q5TDP6

Probable lysosomal cobalamin transporter. Required toexport cobalamin from lysosomes allowing its conversion tocofactors. {ECO:0000269|PubMed:19136951}. (Microbial infection) Isoform 3: May play a role in theassembly of hepatitis delta virus (HDV).{ECO:0000269|PubMed:15956556}. May act as a component of the cytoskeleton or as achaperone for the reorganization of intermediate filament proteinsduring terminal differentiation in the lens. Does not seem to haveenzymatic activity (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715122_144181468Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-7151_10181468Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-71532_50181468Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-71572_100181468Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816122_144254541Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816166_188254541Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-8161_10254541Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-81632_50254541Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-81672_100254541Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715101_121181468TransmembraneHelical%3B Name%3D3
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-71511_31181468TransmembraneHelical%3B Name%3D1
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715145_165181468TransmembraneHelical%3B Name%3D4
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-71551_71181468TransmembraneHelical%3B Name%3D2
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816101_121254541TransmembraneHelical%3B Name%3D3
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-81611_31254541TransmembraneHelical%3B Name%3D1
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816145_165254541TransmembraneHelical%3B Name%3D4
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816189_209254541TransmembraneHelical%3B Name%3D5
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-81651_71254541TransmembraneHelical%3B Name%3D2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715166_188181468Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715210_305181468Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715327_364181468Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715386_408181468Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715430_486181468Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715508_540181468Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816210_305254541Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816327_364254541Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816386_408254541Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816430_486254541Topological domainExtracellular
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816508_540254541Topological domainCytoplasmic
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715189_209181468TransmembraneHelical%3B Name%3D5
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715306_326181468TransmembraneHelical%3B Name%3D6
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715365_385181468TransmembraneHelical%3B Name%3D7
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715409_429181468TransmembraneHelical%3B Name%3D8
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370570-715487_507181468TransmembraneHelical%3B Name%3D9
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816306_326254541TransmembraneHelical%3B Name%3D6
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816365_385254541TransmembraneHelical%3B Name%3D7
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816409_429254541TransmembraneHelical%3B Name%3D8
HgeneLMBRD1chr6:70428848chr6:64004950ENST00000370577-816487_507254541TransmembraneHelical%3B Name%3D9


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FusionGeneSequence for LMBRD1_LGSN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_453aa
MATSGAASAELVIGWCIFGLLLLAILAFCWITVRKYQSRRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANANVS
RQIEDTVLYGYTTLTSVILFCVFFWIPFVYFTTEEKDDDDTSKCTQIKTALKTTLGFVVICALLLLVGAFVPLNVPNNKNSTEWEKVKSL
FEELGSSHGLAALSFSISSLTLIGMLAAITYTATGMSALPLNLIKGTRSAATERLENTEDIEEVEQHIQTIKSKDSTRDEGNETEANSMN
TLRRTRKKVTKPTVCSTEVGETDMSNSNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHG
VCMPRGTLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTVSGMSIGRKTCSAALLELSSSRSLGKNGWQ

>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_754aa
MATSGAASAELVIGWCIFGLLLLAILAFCWITVRKYQSRRESEVVSTITAIFSLAIALITSALLPVDIFLVSYMKNQNGTFKDWANANVS
RQIEDTVLYGYTTLTSVILFCVFFWIPFVYFTTEEKDDDDTSKCTQIKTALKTTLGFVVICALLLLVGAFVPLNVPNNKNSTEWEKVKSL
FEELGSSHGLAALSFSISSLTLIGMLAAITYTATGMSALPLNLIKGTRSAATERLENTEDIEEVEQHIQTIKSKDSTRDEGNETEANSMN
TLRRTRKKVTKPTVCSTEVGETDMSNSNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVSRSKTIPAHFFQEKVSHG
VCMPRGTLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTGEPLLTSPRYIAKRQLSHLQASGFSLLSAF
ITDFCIFGVPEILNSKIISFPALTFLNNHDQPFMQELVDGLTHTGANVESFSSSTRPGQMEISFLPEFGISSADNAFTLRTGVKEVARKT
NYIASFFIETGFCDSGILSHSLWDVDRKKNMFCSTSGTEQLTITGKKWLAGLLKHSAALSCLMAPSVSCRKRTSKDRKDLKKSVPTTWGY
NDNSCIFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLHSSNEVLAGPDESTDFYQVEPSEIPLKLEDALVALEEDQCLRQAL

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_380aa
MKNQNGTFKDWANANVSRQIEDTVLYGYTTLTSVILFCVFFWIPFVYFTTEEKDDDDTSKCTQIKTALKTTLGFVVICALLLLVGAFVPL
NVPNNKNSTEWEKVKSLFEELGSSHGLAALSFSISSLTLIGMLAAITYTATGMSALPLNLIKGTRSAATERLENTEDIEEVEQHIQTIKS
KDSTRDEGNETEANSMNTLRRTRKKVTKPTVCSTEVGETDMSNSNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVS
RSKTIPAHFFQEKVSHGVCMPRGTLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTVSGMSIGRKTCSA

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_681aa
MKNQNGTFKDWANANVSRQIEDTVLYGYTTLTSVILFCVFFWIPFVYFTTEEKDDDDTSKCTQIKTALKTTLGFVVICALLLLVGAFVPL
NVPNNKNSTEWEKVKSLFEELGSSHGLAALSFSISSLTLIGMLAAITYTATGMSALPLNLIKGTRSAATERLENTEDIEEVEQHIQTIKS
KDSTRDEGNETEANSMNTLRRTRKKVTKPTVCSTEVGETDMSNSNDCMRDSSQILTPPQLSSRMKHIRQAMAKNRLQFVRFEATDLHGVS
RSKTIPAHFFQEKVSHGVCMPRGTLEVIPNPKDNEMNNIRATCFNSDIVLMPELSTFRVLPWADRTARVICDTFTVTGEPLLTSPRYIAK
RQLSHLQASGFSLLSAFITDFCIFGVPEILNSKIISFPALTFLNNHDQPFMQELVDGLTHTGANVESFSSSTRPGQMEISFLPEFGISSA
DNAFTLRTGVKEVARKTNYIASFFIETGFCDSGILSHSLWDVDRKKNMFCSTSGTEQLTITGKKWLAGLLKHSAALSCLMAPSVSCRKRT
SKDRKDLKKSVPTTWGYNDNSCIFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLHSSNEVLAGPDESTDFYQVEPSEIPLKL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_1359nt
ATGGCGACTTCTGGCGCGGCCTCGGCGGAGCTGGTGATCGGCTGGTGCATATTCGGCCTCTTACTACTGGCTATTTTGGCATTCTGCTGG
ATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAGTTGTCTCCACCATAACAGCAATTTTTTCTCTAGCAATTGCACTTATCACA
TCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACATGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGC
AGACAGATTGAGGACACTGTATTATACGGTTACTATACTTTATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTAC
TTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAATGTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATT
TGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGAATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTA
TTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGTCATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACT
TACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGATAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGAC
ATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAAAAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAAC
ACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATGTTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGC
ATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCTCTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAG
TTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCAGGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGT
GTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATCCAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGAC
ATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGCCATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACT
GTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAGCACTTCTGGAACTGAGCAGCTCACGATCACTGGGAAAAAATGGTTGGCAG

>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_2262nt
ATGGCGACTTCTGGCGCGGCCTCGGCGGAGCTGGTGATCGGCTGGTGCATATTCGGCCTCTTACTACTGGCTATTTTGGCATTCTGCTGG
ATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAGTTGTCTCCACCATAACAGCAATTTTTTCTCTAGCAATTGCACTTATCACA
TCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACATGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGC
AGACAGATTGAGGACACTGTATTATACGGTTACTATACTTTATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTAC
TTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAATGTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATT
TGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGAATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTA
TTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGTCATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACT
TACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGATAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGAC
ATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAAAAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAAC
ACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATGTTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGC
ATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCTCTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAG
TTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCAGGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGT
GTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATCCAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGAC
ATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGCCATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACT
GGTGAGCCTCTTTTGACTTCCCCAAGGTACATTGCAAAGAGGCAGCTGAGCCATCTGCAGGCCTCTGGCTTTTCCCTGCTTTCTGCTTTC
ATCTATGATTTTTGCATTTTTGGTGTGCCCGAAATTTTAAATTCAAAGATTATATCTTTTCCTGCTTTAACATTTTTAAATAACCATGAT
CAGCCCTTCATGCAGGAACTTGTTGATGGCTTGTATCACACTGGAGCCAATGTCGAGAGTTTTTCCTCCTCTACCAGGCCTGGTCAGATG
GAAATCTCTTTCCTGCCTGAATTTGGCATTAGCTCAGCTGATAATGCATTTACCCTCAGAACAGGTGTCAAAGAAGTGGCAAGGAAATAT
AATTACATTGCCAGCTTCTTCATTGAGACTGGATTTTGTGATTCAGGGATTTTGTCTCATAGTCTCTGGGATGTCGATAGGAAGAAAAAC
ATGTTCTGCAGCACTTCTGGAACTGAGCAGCTCACGATCACTGGGAAAAAATGGTTGGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGC
TGCCTGATGGCGCCTTCTGTTAGCTGCCGAAAGCGTTATTCCAAGGACAGGAAAGACCTGAAGAAGAGTGTGCCTACAACATGGGGATAC
AATGACAACAGCTGTATATTTAATATCAAATGTCATGGAGAGAAAGGCACCCGGATAGAAAATAAACTAGGCTCAGCAACAGCAAACCCT
TACTTGGTGCTGGCTGCAACTGTTGCTGCCGGCTTAGATGGACTTCATAGCAGTAATGAGGTCTTGGCTGGTCCAGATGAGAGCACAGAC
TTTTACCAAGTGGAACCTTCTGAGATCCCTTTAAAACTAGAAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTA
GGAGAAACCTTTATTCGATATTTTGTTGCCATGAAGAAATATGAGTTGGAGAATGAAGAAATAGCTGCAGAGAGAAATAAATTCTTAGAG

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_1140nt
ATGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACT
TTATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAA
TGTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTG
AATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTG
TCATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTG
ATAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCA
AAAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATAT
GTTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTC
TCTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCC
AGGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAAT
CCAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTG
CCATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACTGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCA

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_2043nt
ATGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACT
TTATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAA
TGTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTG
AATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTG
TCATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTG
ATAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCA
AAAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATAT
GTTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTC
TCTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCC
AGGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAAT
CCAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTG
CCATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACTGGTGAGCCTCTTTTGACTTCCCCAAGGTACATTGCAAAG
AGGCAGCTGAGCCATCTGCAGGCCTCTGGCTTTTCCCTGCTTTCTGCTTTCATCTATGATTTTTGCATTTTTGGTGTGCCCGAAATTTTA
AATTCAAAGATTATATCTTTTCCTGCTTTAACATTTTTAAATAACCATGATCAGCCCTTCATGCAGGAACTTGTTGATGGCTTGTATCAC
ACTGGAGCCAATGTCGAGAGTTTTTCCTCCTCTACCAGGCCTGGTCAGATGGAAATCTCTTTCCTGCCTGAATTTGGCATTAGCTCAGCT
GATAATGCATTTACCCTCAGAACAGGTGTCAAAGAAGTGGCAAGGAAATATAATTACATTGCCAGCTTCTTCATTGAGACTGGATTTTGT
GATTCAGGGATTTTGTCTCATAGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAGCACTTCTGGAACTGAGCAGCTCACGATC
ACTGGGAAAAAATGGTTGGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGCTGCCTGATGGCGCCTTCTGTTAGCTGCCGAAAGCGTTAT
TCCAAGGACAGGAAAGACCTGAAGAAGAGTGTGCCTACAACATGGGGATACAATGACAACAGCTGTATATTTAATATCAAATGTCATGGA
GAGAAAGGCACCCGGATAGAAAATAAACTAGGCTCAGCAACAGCAAACCCTTACTTGGTGCTGGCTGCAACTGTTGCTGCCGGCTTAGAT
GGACTTCATAGCAGTAATGAGGTCTTGGCTGGTCCAGATGAGAGCACAGACTTTTACCAAGTGGAACCTTCTGAGATCCCTTTAAAACTA
GAAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTTTATTCGATATTTTGTTGCCATGAAGAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_6141nt
ACTGCGTCCGCACGCGCCCCGCCCCTGAGCAGTCCTTGCTGCCCCGCCCCCGCTCGGCTCGCCGCCAGGGGACGCTAGTGGGTCCAGTCT
CCTTGGCAACCACTTGCTCCTCCCCCTCCGCCCCTTTAACCTTTAGGGTGCGCGGGTGCAGTATATCTCGCGCTCTCTCCCCTTTCCCCC
TCCCCTTTCCCCACCCCGGGCGCTCAGGTTGGTCTGGACCGGAAGCGAAGATGGCGACTTCTGGCGCGGCCTCGGCGGAGCTGGTGATCG
GCTGGTGCATATTCGGCCTCTTACTACTGGCTATTTTGGCATTCTGCTGGATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAG
TTGTCTCCACCATAACAGCAATTTTTTCTCTAGCAATTGCACTTATCACATCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACA
TGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACTT
TATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAAT
GTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGA
ATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGT
CATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGA
TAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAA
AAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATG
TTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCT
CTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCA
GGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATC
CAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGC
CATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACTGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAG
CACTTCTGGAACTGAGCAGCTCACGATCACTGGGAAAAAATGGTTGGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGCTGCCTGATGGC
GCCTTCTGTTAGCTGCCGAAAGCGTTATTCCAAGGACAGGAAAGACCTGAAGAAGAGTGTGCCTACAACATGGGGATACAATGACAACAG
CTGTATATTTAATATCAAATGTCATGGAGAGAAAGGCACCCGGATAGAAAATAAACTAGGCTCAGCAACAGCAAACCCTTACTTGGTGCT
GGCTGCAACTGTTGCTGCCGGCTTAGATGGACTTCATAGCAGTAATGAGGTCTTGGCTGGTCCAGATGAGAGCACAGACTTTTACCAAGT
GGAACCTTCTGAGATCCCTTTAAAACTAGAAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTT
TATTCGATATTTTGTTGCCATGAAGAAATATGAGTTGGAGAATGAAGAAATAGCTGCAGAGAGAAATAAATTCTTAGAGTATTTTATTTA
GAATAGAGCTCACAACTACTCCTTTAGACATGTAATTGTTACTTAAAGCTAATCTACCAAAACAAAAAGACTGAACTTTTGTAATTAACA
ACAGCAACAATAACAAGATTACGAATGCTTTTGACTTTTTTTTTTGTCCATGGAATATTTGACAGATGAAGTAGGACTGCTGAGAAGATT
CTGATAACAGAAACAAACAACAAAGTTGTGGTGAAGCTATAATATGCAAACTTACCAGATCTTGTCAGTCATTTCCTATGTGTATGTTGA
CCTGGATAAGAATATCCAATTTTGGGTGGCAATAAATATATTCGCACATTAAGAAAAAAAAGACTTAAGCATTAGAAAGCAAAATTTAAA
TGACTAAAAAAGAAAAAAAAGAAAAGGAGAAAAAATTTTAATGGTACACATAGGTTATGATTTCCAGGGAGACAAATATACTAATATAGT
CTCGCTAATCAAATAATATTGTGAATCCAGGTTGTATGCACCATTATGGTCTTTCTAAACAAGTTAAATAAACTTTTGCCAAAATATAAT
GACAGGTAGGCAGTTTTCCCCTAAGTCTCTTCTCTTTTCACCCTTCTCCACTAGCTCCTGAAAAGCTTATGAACTTCAAGGTTATAATGT
CCTCAAGAAACAAATCCCTAAGGAATAGAATTGGAGCTGAGAACAACGAGGTCAGATTTTAAAAGTAGTTAAAGCCTTTCTTTTAACAAT
GCCTCATATAGAAGTTCAATACACAAAGTATAGATAGAAAGATGTTTGTGTGTGAGGGTAGGTGGGCTCTGTCTACTCTGCTTCATTCTT
TGAAACTAGATGTTCCTCTGAAACCTCTAGTGCTCTGTGGAGTGTGAGAACAACTGCCTGGCTAGCCAGGGCTATGTTTGGAGTTTAAGT
TTGTTATTCAAATTACTGAATCTGCTGCTCACAGAGGTTGGTACCTCCCCAGAGAATATTACCTGTTCCAGGCCTTTGTTTGAATGAGAT
AATATTGTAACTATCACAAAAGTTTAGCTGCTTTTGGGAAGAAGTCCAAAATCCACTTACTAGCAAATGAAACATTATTCTACTGCTTAG
GATCAAACAGCAGATTTTATGTTCAATTAAAACTGACTGTAGTCTCAATTTAGATAGCAATTGCACAAGCAGAGGATTAGAATTTGGCTC
AGATCCTCTTATTAAAATTCATATTACTCAGTAGCTTAAATAGTGAAAGTCAGTCTATCCTTCACTAATTACTCCCTTCTTTTTTCCTTT
GAGCAGGAGAAGTGTGTTTGGATACATAAGAAGAAAGTTCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATTGCTTGAGGCCAGGAGTTT
GAGTCCAGCCTGGACCACATAGTGAGACCCCTGTTTCTACAAAAAAAAAAAAAAAAATGCCTCGCATGGTGGCACATGCCTGTAGTCCCA
GCTACGTGGGAGGCTGAGAAGGGAGGATCGCTTGAGCCTGGGAGTTTCAGGCTGCAGTGAGCCATAATCACACCACTGCACTCCAGCTTG
GGTGACAGAGTGAGACACTGTCTTAAAAAAAAGAGAAGAATAAAATTCATGGATGCATATGGGGTAGAGAGAAAGATAGTGTAGGGTAGC
TGGGGGAAGGAAGGGAACCTGTCCTGAAACCTCCAGAATGAAATCCCACACATTACATCATGGGAGGGATAAGGAAGACTCTCATGCCAA
TTTTCTAGCTGTCTGCTAGAAAATTCCCCTCTGTTCATTTTCCCCTCTGTTCTCAGTAATAAAACCTCAATATGTTCTTTGAAAGCAATG
AAAAATGAAATGATATTTCTGAGCCTTCATTAAGGTTGGATGTGGTCATGTTATTAGGTTCAGTGCAAAGAGGTGAAAGTAGAAGTGTTG
CATATAAGTTCTTTAGGACATTTTCTTTTCTTTTCTTGTATTTTTTTTTTTTTTCCGAGATGGAGTCTCGCTTTGTCACCCAGGCTGAAG
TGCAATGTGGGGGGGTCTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATCC
CAGGTGCCTGCTACCATGCCTGGCCTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGTCTGGTCTTGAACTCCTGAACTCAGGTGAT
CAGCCTGCCTTGGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCATGCCCTACCACACTTTAGAACATTTTTTTAAATGACGGAT
GCTGTGTGCTCTGCCCTTTCTTTCTCTTGCTGCCTTCACCCTTCCTGCTGAGTGGCCTACAGATAATGTGGCTAGGATTATGTCCTTGGG
AAGGGAGGTTTGCTCCACAGGGTACAGTAATAAGGTGGAATCTCTGCTTTGTAGAGCAGTTTGACTTGCCTACATCCAGATGTTTACCTG
AGAGAGAACCAAACTTCTATCTTCTTTAAGCCACAATGATTTTGATTCTTTGTTAGTTGCAATGAAATTTATTTTCTCTTTTCCATGTGT
GTGTTGTATGTGTGTTTGTGTGTGAGTGTGTGCATATGAGTGGGGAATTTGAGGGATTTGGGGATGAAAGAACAAAGGTATAAGAACCAG
TGAAAGACGACTTCCTCAATATTCCCACTTCTAGAGAGGATAATCTGAGTTAATCAAAGGGATCCACACATCCAAAAAATGGGATTGGCT
CTAACCCATCCCTATAAAGTGGCATATCCCTTTATAGTCCACGGGCCTTAATGAAACATGTCTAATGCATTGACTTCATTTTACCATAAT
GAGTAAAGATGCTGTAAAAAGTCTGATAATCACAGTGTTTGAAGCCGTTTTTTCCCCTTTCGCATTATTAGCATAACTTAAAAACACAGT
ACTCAGGATGCCATGTGAAGGAATTATATAACTAGGAATATTATCTTCAGTATTAAGTGTACAGTCGTGAGTCAAAGAAAATATTCAGCC
ATAGATTACAAATCAGTTGATAACGTAAGTTGGTGTGGCAGTTTCCACCAAGATTTCAGTTAGGTGTGTGCTGATGTATATTCTTGTTCT
TTAAGGCAACCCAAAAAGAGGCATTGGCCAGCAGAGTTCAGGGCCAAAGACAAATTGGGGTAGGTACATGTAAAAATCAGTTATCTATTT
TTCTATTTCTTTCATCTGTTCATAGGCTTTCTATTGTTGAAAGGACTTTCTGCTGATGCTTCTACCTTCTTGGTCTGGGTTAAGAGGGTC
AGACATTCATTCAGCAGCACTTATTGAGCACCATTTGTGTGCTAAGCCTTCAGCTGGGAGCCATCATACTAGGGGAGACCAAAACAAAGA
TGAGCAGACAATGAAAGAGTTTTGGATCTGTGTATCTTAAGCAGAACATAAATAATTTTTTTTGTAGACCTAATGCTGAAAAAAGCTATT
TGGAAAGCTTCTTTATGGCTCGAAAAGGGTGCCTTATAAATAGCTTTACAAAAATTGCTTTCTTATTTTCATTTACTATAATTGTTCTAA
TCAAAGCTTAGGGGAAAAATGTGATTACTGAATTTAAAGTTGGTAATTAAATGAGTATACATAAGAAATGTAAATTAAAAGCGATAATAT
TTTAAGACTAGAAATTAAAACATTAGTATTGTAGTAACAAGTTTCTATTTTCAAGGACATTCTATAATCTAAAATTTCATTTTACAGTGT
GTGAATAACAACAACGCTTGAAATGATTATTTGAAGGCAATGAAAGATCAAAAAACTTTAATCTGAATAAAAATTGAAAGCATACAGTGA
AGTCTGAGCTTATCAGTAAAACAGAACAGTCTATTGACATATCTCCAGTCACCTGTTTGACAAAATACACTCACCAATATGTTTATGATA
TAGGTATGACTGGACAATACCTTTAACCTTGGGTTTTCTATGACAGGGGTAAGAATTTGTGTCTTTAAACATTACCTATGTGCACAGTGC
CTTCCCTGTTAAAGCTCTTCTCATGCTGCCTATAATTAGGGGTTTACATGATACTTCCTAATTGCTAATTAGGATGTGAATTCTCAGAAT

>In-frame_LMBRD1_ENST00000370577_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_2877nt
ACTGCGTCCGCACGCGCCCCGCCCCTGAGCAGTCCTTGCTGCCCCGCCCCCGCTCGGCTCGCCGCCAGGGGACGCTAGTGGGTCCAGTCT
CCTTGGCAACCACTTGCTCCTCCCCCTCCGCCCCTTTAACCTTTAGGGTGCGCGGGTGCAGTATATCTCGCGCTCTCTCCCCTTTCCCCC
TCCCCTTTCCCCACCCCGGGCGCTCAGGTTGGTCTGGACCGGAAGCGAAGATGGCGACTTCTGGCGCGGCCTCGGCGGAGCTGGTGATCG
GCTGGTGCATATTCGGCCTCTTACTACTGGCTATTTTGGCATTCTGCTGGATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAG
TTGTCTCCACCATAACAGCAATTTTTTCTCTAGCAATTGCACTTATCACATCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACA
TGAAAAATCAAAATGGTACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACTT
TATATTCTGTTATATTGTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAAT
GTACTCAAATTAAAACGGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGA
ATGTTCCCAATAACAAAAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGT
CATTTTCTATCAGTTCTCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGA
TAAAAGGCACTAGAAGCGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAA
AAGACTCAACAAGAGATGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATG
TTTGTTCAACTGAAGTGGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCT
CTTCTAGAATGAAACACATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCA
GGTCTAAGACTATCCCTGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATC
CAAAGGACAATGAAATGAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGC
CATGGGCTGACAGAACTGCAAGAGTGATATGTGATACCTTCACTGTGACTGGTGAGCCTCTTTTGACTTCCCCAAGGTACATTGCAAAGA
GGCAGCTGAGCCATCTGCAGGCCTCTGGCTTTTCCCTGCTTTCTGCTTTCATCTATGATTTTTGCATTTTTGGTGTGCCCGAAATTTTAA
ATTCAAAGATTATATCTTTTCCTGCTTTAACATTTTTAAATAACCATGATCAGCCCTTCATGCAGGAACTTGTTGATGGCTTGTATCACA
CTGGAGCCAATGTCGAGAGTTTTTCCTCCTCTACCAGGCCTGGTCAGATGGAAATCTCTTTCCTGCCTGAATTTGGCATTAGCTCAGCTG
ATAATGCATTTACCCTCAGAACAGGTGTCAAAGAAGTGGCAAGGAAATATAATTACATTGCCAGCTTCTTCATTGAGACTGGATTTTGTG
ATTCAGGGATTTTGTCTCATAGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAGCACTTCTGGAACTGAGCAGCTCACGATCA
CTGGGAAAAAATGGTTGGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGCTGCCTGATGGCGCCTTCTGTTAGCTGCCGAAAGCGTTATT
CCAAGGACAGGAAAGACCTGAAGAAGAGTGTGCCTACAACATGGGGATACAATGACAACAGCTGTATATTTAATATCAAATGTCATGGAG
AGAAAGGCACCCGGATAGAAAATAAACTAGGCTCAGCAACAGCAAACCCTTACTTGGTGCTGGCTGCAACTGTTGCTGCCGGCTTAGATG
GACTTCATAGCAGTAATGAGGTCTTGGCTGGTCCAGATGAGAGCACAGACTTTTACCAAGTGGAACCTTCTGAGATCCCTTTAAAACTAG
AAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTTTATTCGATATTTTGTTGCCATGAAGAAAT
ATGAGTTGGAGAATGAAGAAATAGCTGCAGAGAGAAATAAATTCTTAGAGTATTTTATTTAGAATAGAGCTCACAACTACTCCTTTAGAC
ATGTAATTGTTACTTAAAGCTAATCTACCAAAACAAAAAGACTGAACTTTTGTAATTAACAACAGCAACAATAACAAGATTACGAATGCT
TTTGACTTTTTTTTTTGTCCATGGAATATTTGACAGATGAAGTAGGACTGCTGAGAAGATTCTGATAACAGAAACAAACAACAAAGTTGT
GGTGAAGCTATAATATGCAAACTTACCAGATCTTGTCAGTCATTTCCTATGTGTATGTTGACCTGGATAAGAATATCCAATTTTGGGTGG

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370658_chr6_64004950_-_6035nt
GTACTGCATTCATGAAGTAGGCTTTGAAAATTATACATCTTGGACAAGTTTTTAAGGGATAGTGGGCTTTCCTTACACAACTAAAATAAC
CTTTACTTCACATAAGGTTTCCTGCTAGAAACTTTCAAACACATACAAAAATCAGAGAAAATACACTGGGTAGTAACAAACATCTCTTTT
TGTTCTATTTCAGGCTATTTTGGCATTCTGCTGGATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAGTTGTCTCCACCATAAC
AGCAATTTTTTCTCTAGCAATTGCACTTATCACATCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACATGAAAAATCAAAATGG
TACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACTTTATATTCTGTTATATT
GTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAATGTACTCAAATTAAAAC
GGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGAATGTTCCCAATAACAA
AAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGTCATTTTCTATCAGTTC
TCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGATAAAAGGCACTAGAAG
CGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAAAAGACTCAACAAGAGA
TGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATGTTTGTTCAACTGAAGT
GGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCTCTTCTAGAATGAAACA
CATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCAGGTCTAAGACTATCCC
TGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATCCAAAGGACAATGAAAT
GAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGCCATGGGCTGACAGAAC
TGCAAGAGTGATATGTGATACCTTCACTGTGACTGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAGCACTTCTGGAACTGAG
CAGCTCACGATCACTGGGAAAAAATGGTTGGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGCTGCCTGATGGCGCCTTCTGTTAGCTGC
CGAAAGCGTTATTCCAAGGACAGGAAAGACCTGAAGAAGAGTGTGCCTACAACATGGGGATACAATGACAACAGCTGTATATTTAATATC
AAATGTCATGGAGAGAAAGGCACCCGGATAGAAAATAAACTAGGCTCAGCAACAGCAAACCCTTACTTGGTGCTGGCTGCAACTGTTGCT
GCCGGCTTAGATGGACTTCATAGCAGTAATGAGGTCTTGGCTGGTCCAGATGAGAGCACAGACTTTTACCAAGTGGAACCTTCTGAGATC
CCTTTAAAACTAGAAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTTTATTCGATATTTTGTT
GCCATGAAGAAATATGAGTTGGAGAATGAAGAAATAGCTGCAGAGAGAAATAAATTCTTAGAGTATTTTATTTAGAATAGAGCTCACAAC
TACTCCTTTAGACATGTAATTGTTACTTAAAGCTAATCTACCAAAACAAAAAGACTGAACTTTTGTAATTAACAACAGCAACAATAACAA
GATTACGAATGCTTTTGACTTTTTTTTTTGTCCATGGAATATTTGACAGATGAAGTAGGACTGCTGAGAAGATTCTGATAACAGAAACAA
ACAACAAAGTTGTGGTGAAGCTATAATATGCAAACTTACCAGATCTTGTCAGTCATTTCCTATGTGTATGTTGACCTGGATAAGAATATC
CAATTTTGGGTGGCAATAAATATATTCGCACATTAAGAAAAAAAAGACTTAAGCATTAGAAAGCAAAATTTAAATGACTAAAAAAGAAAA
AAAAGAAAAGGAGAAAAAATTTTAATGGTACACATAGGTTATGATTTCCAGGGAGACAAATATACTAATATAGTCTCGCTAATCAAATAA
TATTGTGAATCCAGGTTGTATGCACCATTATGGTCTTTCTAAACAAGTTAAATAAACTTTTGCCAAAATATAATGACAGGTAGGCAGTTT
TCCCCTAAGTCTCTTCTCTTTTCACCCTTCTCCACTAGCTCCTGAAAAGCTTATGAACTTCAAGGTTATAATGTCCTCAAGAAACAAATC
CCTAAGGAATAGAATTGGAGCTGAGAACAACGAGGTCAGATTTTAAAAGTAGTTAAAGCCTTTCTTTTAACAATGCCTCATATAGAAGTT
CAATACACAAAGTATAGATAGAAAGATGTTTGTGTGTGAGGGTAGGTGGGCTCTGTCTACTCTGCTTCATTCTTTGAAACTAGATGTTCC
TCTGAAACCTCTAGTGCTCTGTGGAGTGTGAGAACAACTGCCTGGCTAGCCAGGGCTATGTTTGGAGTTTAAGTTTGTTATTCAAATTAC
TGAATCTGCTGCTCACAGAGGTTGGTACCTCCCCAGAGAATATTACCTGTTCCAGGCCTTTGTTTGAATGAGATAATATTGTAACTATCA
CAAAAGTTTAGCTGCTTTTGGGAAGAAGTCCAAAATCCACTTACTAGCAAATGAAACATTATTCTACTGCTTAGGATCAAACAGCAGATT
TTATGTTCAATTAAAACTGACTGTAGTCTCAATTTAGATAGCAATTGCACAAGCAGAGGATTAGAATTTGGCTCAGATCCTCTTATTAAA
ATTCATATTACTCAGTAGCTTAAATAGTGAAAGTCAGTCTATCCTTCACTAATTACTCCCTTCTTTTTTCCTTTGAGCAGGAGAAGTGTG
TTTGGATACATAAGAAGAAAGTTCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATTGCTTGAGGCCAGGAGTTTGAGTCCAGCCTGGACC
ACATAGTGAGACCCCTGTTTCTACAAAAAAAAAAAAAAAAATGCCTCGCATGGTGGCACATGCCTGTAGTCCCAGCTACGTGGGAGGCTG
AGAAGGGAGGATCGCTTGAGCCTGGGAGTTTCAGGCTGCAGTGAGCCATAATCACACCACTGCACTCCAGCTTGGGTGACAGAGTGAGAC
ACTGTCTTAAAAAAAAGAGAAGAATAAAATTCATGGATGCATATGGGGTAGAGAGAAAGATAGTGTAGGGTAGCTGGGGGAAGGAAGGGA
ACCTGTCCTGAAACCTCCAGAATGAAATCCCACACATTACATCATGGGAGGGATAAGGAAGACTCTCATGCCAATTTTCTAGCTGTCTGC
TAGAAAATTCCCCTCTGTTCATTTTCCCCTCTGTTCTCAGTAATAAAACCTCAATATGTTCTTTGAAAGCAATGAAAAATGAAATGATAT
TTCTGAGCCTTCATTAAGGTTGGATGTGGTCATGTTATTAGGTTCAGTGCAAAGAGGTGAAAGTAGAAGTGTTGCATATAAGTTCTTTAG
GACATTTTCTTTTCTTTTCTTGTATTTTTTTTTTTTTTCCGAGATGGAGTCTCGCTTTGTCACCCAGGCTGAAGTGCAATGTGGGGGGGT
CTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGTAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATCCCAGGTGCCTGCTACCA
TGCCTGGCCTTTTAGTAGAGATGGGGTTTCACCATATTGGCCAGTCTGGTCTTGAACTCCTGAACTCAGGTGATCAGCCTGCCTTGGCCT
CCCAAAGTGCTAGGATTACAGGCATGAGCCACCATGCCCTACCACACTTTAGAACATTTTTTTAAATGACGGATGCTGTGTGCTCTGCCC
TTTCTTTCTCTTGCTGCCTTCACCCTTCCTGCTGAGTGGCCTACAGATAATGTGGCTAGGATTATGTCCTTGGGAAGGGAGGTTTGCTCC
ACAGGGTACAGTAATAAGGTGGAATCTCTGCTTTGTAGAGCAGTTTGACTTGCCTACATCCAGATGTTTACCTGAGAGAGAACCAAACTT
CTATCTTCTTTAAGCCACAATGATTTTGATTCTTTGTTAGTTGCAATGAAATTTATTTTCTCTTTTCCATGTGTGTGTTGTATGTGTGTT
TGTGTGTGAGTGTGTGCATATGAGTGGGGAATTTGAGGGATTTGGGGATGAAAGAACAAAGGTATAAGAACCAGTGAAAGACGACTTCCT
CAATATTCCCACTTCTAGAGAGGATAATCTGAGTTAATCAAAGGGATCCACACATCCAAAAAATGGGATTGGCTCTAACCCATCCCTATA
AAGTGGCATATCCCTTTATAGTCCACGGGCCTTAATGAAACATGTCTAATGCATTGACTTCATTTTACCATAATGAGTAAAGATGCTGTA
AAAAGTCTGATAATCACAGTGTTTGAAGCCGTTTTTTCCCCTTTCGCATTATTAGCATAACTTAAAAACACAGTACTCAGGATGCCATGT
GAAGGAATTATATAACTAGGAATATTATCTTCAGTATTAAGTGTACAGTCGTGAGTCAAAGAAAATATTCAGCCATAGATTACAAATCAG
TTGATAACGTAAGTTGGTGTGGCAGTTTCCACCAAGATTTCAGTTAGGTGTGTGCTGATGTATATTCTTGTTCTTTAAGGCAACCCAAAA
AGAGGCATTGGCCAGCAGAGTTCAGGGCCAAAGACAAATTGGGGTAGGTACATGTAAAAATCAGTTATCTATTTTTCTATTTCTTTCATC
TGTTCATAGGCTTTCTATTGTTGAAAGGACTTTCTGCTGATGCTTCTACCTTCTTGGTCTGGGTTAAGAGGGTCAGACATTCATTCAGCA
GCACTTATTGAGCACCATTTGTGTGCTAAGCCTTCAGCTGGGAGCCATCATACTAGGGGAGACCAAAACAAAGATGAGCAGACAATGAAA
GAGTTTTGGATCTGTGTATCTTAAGCAGAACATAAATAATTTTTTTTGTAGACCTAATGCTGAAAAAAGCTATTTGGAAAGCTTCTTTAT
GGCTCGAAAAGGGTGCCTTATAAATAGCTTTACAAAAATTGCTTTCTTATTTTCATTTACTATAATTGTTCTAATCAAAGCTTAGGGGAA
AAATGTGATTACTGAATTTAAAGTTGGTAATTAAATGAGTATACATAAGAAATGTAAATTAAAAGCGATAATATTTTAAGACTAGAAATT
AAAACATTAGTATTGTAGTAACAAGTTTCTATTTTCAAGGACATTCTATAATCTAAAATTTCATTTTACAGTGTGTGAATAACAACAACG
CTTGAAATGATTATTTGAAGGCAATGAAAGATCAAAAAACTTTAATCTGAATAAAAATTGAAAGCATACAGTGAAGTCTGAGCTTATCAG
TAAAACAGAACAGTCTATTGACATATCTCCAGTCACCTGTTTGACAAAATACACTCACCAATATGTTTATGATATAGGTATGACTGGACA
ATACCTTTAACCTTGGGTTTTCTATGACAGGGGTAAGAATTTGTGTCTTTAAACATTACCTATGTGCACAGTGCCTTCCCTGTTAAAGCT
CTTCTCATGCTGCCTATAATTAGGGGTTTACATGATACTTCCTAATTGCTAATTAGGATGTGAATTCTCAGAATAAAAGGTACAGATCTT

>In-frame_LMBRD1_ENST00000370570_chr6_70428848_-_LGSN_ENST00000370657_chr6_64004950_-_2771nt
GTACTGCATTCATGAAGTAGGCTTTGAAAATTATACATCTTGGACAAGTTTTTAAGGGATAGTGGGCTTTCCTTACACAACTAAAATAAC
CTTTACTTCACATAAGGTTTCCTGCTAGAAACTTTCAAACACATACAAAAATCAGAGAAAATACACTGGGTAGTAACAAACATCTCTTTT
TGTTCTATTTCAGGCTATTTTGGCATTCTGCTGGATATATGTTCGTAAATACCAAAGTCGGCGGGAAAGTGAAGTTGTCTCCACCATAAC
AGCAATTTTTTCTCTAGCAATTGCACTTATCACATCAGCACTTCTACCAGTGGATATATTTTTGGTTTCTTACATGAAAAATCAAAATGG
TACATTTAAGGACTGGGCTAATGCTAATGTCAGCAGACAGATTGAGGACACTGTATTATACGGTTACTATACTTTATATTCTGTTATATT
GTTCTGTGTGTTCTTCTGGATCCCTTTTGTCTACTTCTATTATGAAGAAAAGGATGATGATGATACTAGTAAATGTACTCAAATTAAAAC
GGCACTCAAGTATACTTTGGGATTTGTTGTGATTTGTGCACTGCTTCTTTTAGTTGGTGCCTTTGTTCCATTGAATGTTCCCAATAACAA
AAATTCTACAGAGTGGGAAAAAGTGAAGTCCCTATTTGAAGAACTTGGAAGTAGTCATGGTTTAGCTGCATTGTCATTTTCTATCAGTTC
TCTGACCTTGATTGGAATGTTGGCAGCTATAACTTACACAGCCTATGGCATGTCTGCGTTACCTTTAAATCTGATAAAAGGCACTAGAAG
CGCTGCTTATGAACGTTTGGAAAACACTGAAGACATTGAAGAAGTAGAACAACACATTCAAACGATTAAATCAAAAGACTCAACAAGAGA
TGAAGGCAATGAGACTGAAGCCAACAGCATGAACACATTAAGAAGGACAAGGAAGAAAGTCACTAAACCATATGTTTGTTCAACTGAAGT
GGGAGAAACGGATATGTCCAATTCAAATGATTGCATGAGGGACAGCAGTCAAATTTTGACCCCACCTCAACTCTCTTCTAGAATGAAACA
CATTAGACAAGCCATGGCCAAAAATCGCCTCCAGTTTGTACGATTTGAAGCAACAGACCTCCACGGCGTGTCCAGGTCTAAGACTATCCC
TGCACACTTTTTTCAAGAGAAAGTGAGCCATGGTGTTTGCATGCCCCGAGGTTATCTTGAAGTGATACCAAATCCAAAGGACAATGAAAT
GAATAACATAAGAGCCACATGTTTTAATAGCGACATAGTCCTAATGCCAGAGTTATCAACCTTTAGAGTTTTGCCATGGGCTGACAGAAC
TGCAAGAGTGATATGTGATACCTTCACTGTGACTGGTGAGCCTCTTTTGACTTCCCCAAGGTACATTGCAAAGAGGCAGCTGAGCCATCT
GCAGGCCTCTGGCTTTTCCCTGCTTTCTGCTTTCATCTATGATTTTTGCATTTTTGGTGTGCCCGAAATTTTAAATTCAAAGATTATATC
TTTTCCTGCTTTAACATTTTTAAATAACCATGATCAGCCCTTCATGCAGGAACTTGTTGATGGCTTGTATCACACTGGAGCCAATGTCGA
GAGTTTTTCCTCCTCTACCAGGCCTGGTCAGATGGAAATCTCTTTCCTGCCTGAATTTGGCATTAGCTCAGCTGATAATGCATTTACCCT
CAGAACAGGTGTCAAAGAAGTGGCAAGGAAATATAATTACATTGCCAGCTTCTTCATTGAGACTGGATTTTGTGATTCAGGGATTTTGTC
TCATAGTCTCTGGGATGTCGATAGGAAGAAAAACATGTTCTGCAGCACTTCTGGAACTGAGCAGCTCACGATCACTGGGAAAAAATGGTT
GGCAGGACTCTTGAAGCACTCTGCTGCGCTCAGCTGCCTGATGGCGCCTTCTGTTAGCTGCCGAAAGCGTTATTCCAAGGACAGGAAAGA
CCTGAAGAAGAGTGTGCCTACAACATGGGGATACAATGACAACAGCTGTATATTTAATATCAAATGTCATGGAGAGAAAGGCACCCGGAT
AGAAAATAAACTAGGCTCAGCAACAGCAAACCCTTACTTGGTGCTGGCTGCAACTGTTGCTGCCGGCTTAGATGGACTTCATAGCAGTAA
TGAGGTCTTGGCTGGTCCAGATGAGAGCACAGACTTTTACCAAGTGGAACCTTCTGAGATCCCTTTAAAACTAGAAGATGCCCTTGTGGC
ACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTTTATTCGATATTTTGTTGCCATGAAGAAATATGAGTTGGAGAATGA
AGAAATAGCTGCAGAGAGAAATAAATTCTTAGAGTATTTTATTTAGAATAGAGCTCACAACTACTCCTTTAGACATGTAATTGTTACTTA
AAGCTAATCTACCAAAACAAAAAGACTGAACTTTTGTAATTAACAACAGCAACAATAACAAGATTACGAATGCTTTTGACTTTTTTTTTT
GTCCATGGAATATTTGACAGATGAAGTAGGACTGCTGAGAAGATTCTGATAACAGAAACAAACAACAAAGTTGTGGTGAAGCTATAATAT
GCAAACTTACCAGATCTTGTCAGTCATTTCCTATGTGTATGTTGACCTGGATAAGAATATCCAATTTTGGGTGGCAATAAATATATTCGC


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FusionGenePPI for LMBRD1_LGSN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
LMBRD1HNRNPC, CSGALNACT2, MBOAT7LGSNTBCB


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LMBRD1_LGSN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneLGSNQ5TDP6DB00142Glutamic AcidLengsinsmall moleculeapproved|nutraceutical

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RelatedDiseases for LMBRD1_LGSN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource