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Fusion gene ID: 19455 |
FusionGeneSummary for LARGE_GRAMD4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LARGE_GRAMD4 | Fusion gene ID: 19455 | Hgene | Tgene | Gene symbol | LARGE | GRAMD4 | Gene ID | 9215 | 23151 |
| Gene name | LARGE xylosyl- and glucuronyltransferase 1 | GRAM domain containing 4 | |
| Synonyms | LARGE|MDC1D|MDDGA6|MDDGB6 | DIP|dA59H18.1|dJ439F8.1 | |
| Cytomap | 22q12.3 | 22q13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | LARGE xylosyl- and glucuronyltransferase 1acetylglucosaminyltransferase-like 1Aacetylglucosaminyltransferase-like proteinglycosyltransferase-like protein LARGE1 | GRAM domain-containing protein 4death-inducing-protein | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q6IC98 | ||
| Ensembl transtripts involved in fusion gene | ENST00000337431, ENST00000354992, ENST00000397394, ENST00000402320, ENST00000452586, ENST00000437602, ENST00000421232, | ENST00000406902, ENST00000361034, ENST00000490378, ENST00000408031, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 5 X 3 X 4=60 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LARGE [Title/Abstract] AND GRAMD4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | LARGE | GO:0035269 | protein O-linked mannosylation | 22223806|25138275|25279697|25279699 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | TGCT | TCGA-2G-AAGP-01A | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000337431 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000337431 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000337431 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000337431 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000354992 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000354992 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000354992 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000354992 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000397394 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000397394 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000397394 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000397394 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000402320 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000402320 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000402320 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000402320 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000452586 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| Frame-shift | ENST00000452586 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000452586 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000452586 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| In-frame | ENST00000437602 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| In-frame | ENST00000437602 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-3UTR | ENST00000437602 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| 5CDS-intron | ENST00000437602 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| intron-3CDS | ENST00000421232 | ENST00000406902 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| intron-3CDS | ENST00000421232 | ENST00000361034 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| intron-3UTR | ENST00000421232 | ENST00000490378 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
| intron-intron | ENST00000421232 | ENST00000408031 | LARGE | chr22 | 33712071 | - | GRAMD4 | chr22 | 47033737 | + |
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FusionProtFeatures for LARGE_GRAMD4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LARGE | GRAMD4 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Plays a role as a mediator of E2F1-induced apoptosis inthe absence of p53/TP53. {ECO:0000269|PubMed:15565177}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for LARGE_GRAMD4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000406902_chr22_47033737_+_1008aa MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRMREVEEENRALRRQLSLAQGRA PSHRRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLV ENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRER FTVHRTHLYFLHYEYEPAADSTDVTLVAQLSMDRLVQGPSSWPQESRTLTGQSLIDXMRSKVTWKLPYWKNISYRRSSGSCEKKPTRRCC GRSWTASGSGGWSWSRRCRRCXRPEPRSRWLSSPQKGRPRPAMEQSAGARGCPRACRSGSTSGLGSTWRTSGSSPRRTLWRQRNPXAPAG XLKIXDGSSAVPSRSLTLXRTSLPYPTGTPSTRLPLPSPCTXMPCGMAGPSHCSYFXQFXGYPSITSSPGGGGYSGASCPKCLSPWNLQR KTXLCLRSSSWCWTSPRKPRTFSGRWLTSWRRSRTCSCGSSRRSHRSCMWRSGLPSWPPASSPTAWWGLPWDSMLVSSSSSLISSLNAAR GCAPSTTRPISSGGVSPPTRSSRSAPAPQSHAGCRRPRHGATYPAHRPAWVKRRTPVASTAPRRAISTRSSIXQKTSVRWRCARMAGAAA SSTGTGRCPRTTSGTGCSTSRRITCASKAPNLGPQRGTKSSSXWTSRTSRSTRSCLSSQAQAWGLPCRRHPPRNRSCLVPWCTGMRPSRP >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000361034_chr22_47033737_+_1008aa MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQRERESLEVRMREVEEENRALRRQLSLAQGRA PSHRRGNHSKTYSMEEGTGDSENLRAGIVAGNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIVLDTDITFATDIAELWAVFHKFKGQQVLGLV ENQSDWYLGNLWKNHRPWPALGRGYNTGVILLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCPSEADVNSENLQKQLSELDEDDLCYEFRRER FTVHRTHLYFLHYEYEPAADSTDVTLVAQLSMDRLVQGPSSWPQESRTLTGQSLIDXMRSKVTWKLPYWKNISYRRSSGSCEKKPTRRCC GRSWTASGSGGWSWSRRCRRCXRPEPRSRWLSSPQKGRPRPAMEQSAGARGCPRACRSGSTSGLGSTWRTSGSSPRRTLWRQRNPXAPAG XLKIXDGSSAVPSRSLTLXRTSLPYPTGTPSTRLPLPSPCTXMPCGMAGPSHCSYFXQFXGYPSITSSPGGGGYSGASCPKCLSPWNLQR KTXLCLRSSSWCWTSPRKPRTFSGRWLTSWRRSRTCSCGSSRRSHRSCMWRSGLPSWPPASSPTAWWGLPWDSMLVSSSSSLISSLNAAR GCAPSTTRPISSGGVSPPTRSSRSAPAPQSHAGCRRPRHGATYPAHRPAWVKRRTPVASTAPRRAISTRSSIXQKTSVRWRCARMAGAAA SSTGTGRCPRTTSGTGCSTSRRITCASKAPNLGPQRGTKSSSXWTSRTSRSTRSCLSSQAQAWGLPCRRHPPRNRSCLVPWCTGMRPSRP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000406902_chr22_47033737_+_3026nt ATGCTGGGAATCTGCAGGGGGAGACGGAAATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCCCAGCCATCACCTGGATTTACCTGTTT TCTGGGAGCTTCGAAGATGGAAAGCCCGTGTCTCTGTCACCGCTGGAGTCCCAGGCACACAGCCCCAGGTACACGGCCTCCAGCCAGCGG GAGCGCGAGAGCCTGGAGGTGCGCATGCGCGAGGTGGAGGAGGAGAACCGCGCCCTCCGCAGGCAGCTCAGCCTGGCCCAGGGCCGAGCC CCATCCCATCGCCGAGGCAACCACTCCAAGACCTACTCCATGGAGGAGGGCACTGGAGACAGCGAGAACCTTCGGGCTGGCATCGTGGCA GGCAACAGCTCCGAGTGTGGGCAGCAGCCGGTCGTGGAGAAATGCGAGACAATCCACGTTGCTATTGTCTGCGCCGGATACAATGCCAGC CGGGATGTCGTCACCCTGGTCAAATCCGTCCTGTTCCATAGACGGAACCCTCTGCACTTCCACCTTATTGCTGACTCCATTGCGGAGCAG ATCCTGGCCACGCTCTTCCAGACCTGGATGGTGCCCGCTGTGCGTGTGGACTTCTACAATGCAGACGAGCTCAAGTCTGAAGTTTCCTGG ATCCCCAATAAACATTACTCTGGGATTTATGGTCTGATGAAGCTTGTCCTGACCAAGACTCTTCCTGCCAACCTGGAGAGAGTCATCGTC CTTGACACGGATATCACCTTTGCCACTGACATTGCAGAGCTGTGGGCTGTGTTCCACAAGTTCAAAGGTCAGCAAGTCCTGGGCTTGGTG GAGAACCAGAGTGACTGGTACCTTGGAAACCTGTGGAAAAATCACCGCCCATGGCCAGCCCTTGGAAGAGGCTACAACACAGGGGTGATC CTGTTACTTCTGGATAAGCTGCGGAAGATGAAATGGGAGCAGATGTGGAGGCTGACCGCAGAGAGGGAGCTCATGGGCATGCTCTCTACA TCCTTAGCTGACCAGGATATTTTCAATGCCGTCATCAAACAAAACCCCTTCCTTGTGTACCAGCTCCCCTGCTTCTGGAATGTGCAGCTG TCAGACCACACCCGCTCCGAGCAGTGCTACAGAGACGTGTCTGATCTAAAGGTCATTCACTGGAACTCCCCCAAGAAGCTCCGGGTGAAG AACAAGCATGTGGAGTTTTTTCGCAACCTCTACCTGACCTTCCTGGAGTATGACGGCAATCTTCTGAGGCGGGAACTGTTTGGCTGCCCC AGTGAGGCTGATGTCAACAGTGAAAACCTCCAGAAGCAGCTGTCTGAGCTGGACGAGGACGACCTGTGCTATGAGTTCCGGCGAGAGCGC TTCACTGTCCACCGCACCCACCTGTACTTCCTGCACTACGAGTATGAGCCTGCAGCAGACAGCACGGACGTCACCCTGGTCGCTCAGCTG TCCATGGACAGGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCA AAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCGGAGATGCTGC GGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAGGAGCAGATGG CTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAGAAGTGGTTCT ACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGCGCCCGCAGGT TAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGACTGGTACTCCG TCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTAGCAATTCTGA GGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAACCTCCAAAGG AAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCTGACATCCTGG AGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTGGCCTCCTGCT TCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAACGCTGCCCGA GGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGCGCCGCAGTCT CACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGTCGCTTCCACA GCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGTGTGCGAGAATGGCTGGCGCTGCTGCC TCATCAACAGGGACCGGAAGATGCCCACGGACTACATCAGGAACGGGGTGCTCTACGTCACGGAGAATTACTTGTGCTTCGAAAGCTCCA AATCTGGGTCCTCAAAGAGGAACAAAGTCATCAAGCTAGTGGACATCACGGACATCCAGAAGTACAAGGTCCTGTCTGTCCTCCCAGGCT CAGGCATGGGGATTGCCGTGTCGACGCCATCCACCCAGAAACCGCTCGTGTTTGGTGCCATGGTGCACAGGGATGAGGCCTTCGAGACCA >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000361034_chr22_47033737_+_3026nt ATGCTGGGAATCTGCAGGGGGAGACGGAAATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCCCAGCCATCACCTGGATTTACCTGTTT TCTGGGAGCTTCGAAGATGGAAAGCCCGTGTCTCTGTCACCGCTGGAGTCCCAGGCACACAGCCCCAGGTACACGGCCTCCAGCCAGCGG GAGCGCGAGAGCCTGGAGGTGCGCATGCGCGAGGTGGAGGAGGAGAACCGCGCCCTCCGCAGGCAGCTCAGCCTGGCCCAGGGCCGAGCC CCATCCCATCGCCGAGGCAACCACTCCAAGACCTACTCCATGGAGGAGGGCACTGGAGACAGCGAGAACCTTCGGGCTGGCATCGTGGCA GGCAACAGCTCCGAGTGTGGGCAGCAGCCGGTCGTGGAGAAATGCGAGACAATCCACGTTGCTATTGTCTGCGCCGGATACAATGCCAGC CGGGATGTCGTCACCCTGGTCAAATCCGTCCTGTTCCATAGACGGAACCCTCTGCACTTCCACCTTATTGCTGACTCCATTGCGGAGCAG ATCCTGGCCACGCTCTTCCAGACCTGGATGGTGCCCGCTGTGCGTGTGGACTTCTACAATGCAGACGAGCTCAAGTCTGAAGTTTCCTGG ATCCCCAATAAACATTACTCTGGGATTTATGGTCTGATGAAGCTTGTCCTGACCAAGACTCTTCCTGCCAACCTGGAGAGAGTCATCGTC CTTGACACGGATATCACCTTTGCCACTGACATTGCAGAGCTGTGGGCTGTGTTCCACAAGTTCAAAGGTCAGCAAGTCCTGGGCTTGGTG GAGAACCAGAGTGACTGGTACCTTGGAAACCTGTGGAAAAATCACCGCCCATGGCCAGCCCTTGGAAGAGGCTACAACACAGGGGTGATC CTGTTACTTCTGGATAAGCTGCGGAAGATGAAATGGGAGCAGATGTGGAGGCTGACCGCAGAGAGGGAGCTCATGGGCATGCTCTCTACA TCCTTAGCTGACCAGGATATTTTCAATGCCGTCATCAAACAAAACCCCTTCCTTGTGTACCAGCTCCCCTGCTTCTGGAATGTGCAGCTG TCAGACCACACCCGCTCCGAGCAGTGCTACAGAGACGTGTCTGATCTAAAGGTCATTCACTGGAACTCCCCCAAGAAGCTCCGGGTGAAG AACAAGCATGTGGAGTTTTTTCGCAACCTCTACCTGACCTTCCTGGAGTATGACGGCAATCTTCTGAGGCGGGAACTGTTTGGCTGCCCC AGTGAGGCTGATGTCAACAGTGAAAACCTCCAGAAGCAGCTGTCTGAGCTGGACGAGGACGACCTGTGCTATGAGTTCCGGCGAGAGCGC TTCACTGTCCACCGCACCCACCTGTACTTCCTGCACTACGAGTATGAGCCTGCAGCAGACAGCACGGACGTCACCCTGGTCGCTCAGCTG TCCATGGACAGGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAGTTTGATCGACTGAATGAGATCA AAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAAGAAACCAACGCGGAGATGCTGC GGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAGGCCAGAACCGAGGAGCAGATGG CTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCCTCGCGCCTGCAGAAGTGGTTCT ACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAGGAACCCCTGAGCGCCCGCAGGT TAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCTGCCTTATCCGACTGGTACTCCG TCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTGTTCTTATTTCTAGCAATTCTGA GGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCTGAGCCCGTGGAACCTCCAAAGG AAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTCGGGAAGATGGCTGACATCCTGG AGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGGGCTGCCTTCCTGGCCTCCTGCT TCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGATTTCATCTTTAAACGCTGCCCGA GGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAGGAGCGCTCCAGCGCCGCAGTCT CACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAGGAGGACGCCGGTCGCTTCCACA GCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGTGTGCGAGAATGGCTGGCGCTGCTGCC TCATCAACAGGGACCGGAAGATGCCCACGGACTACATCAGGAACGGGGTGCTCTACGTCACGGAGAATTACTTGTGCTTCGAAAGCTCCA AATCTGGGTCCTCAAAGAGGAACAAAGTCATCAAGCTAGTGGACATCACGGACATCCAGAAGTACAAGGTCCTGTCTGTCCTCCCAGGCT CAGGCATGGGGATTGCCGTGTCGACGCCATCCACCCAGAAACCGCTCGTGTTTGGTGCCATGGTGCACAGGGATGAGGCCTTCGAGACCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000406902_chr22_47033737_+_5762nt GCAGTTAACTTATCCCGAAGCTCCAAAGCAAACGTCTTTTACTTCTTCGCCGGGGACGCTGCTGTACCACCGCTGCCTCCCTTTCGCATT CTGCTGGGCTCGGTCAGCCGCTGAGATTAGAGAGTATTATGAGGGAGGCCGAGGACTTCATGCTCCGGACAGAGAAACGGCGCTGGGATT AGGGATTGCCACTTCTGAGAGGATGCTGGGAATCTGCAGGGGGAGACGGAAATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCCCAGC CATCACCTGGATTTACCTGTTTTCTGGGAGCTTCGAAGATGGAAAGCCCGTGTCTCTGTCACCGCTGGAGTCCCAGGCACACAGCCCCAG GTACACGGCCTCCAGCCAGCGGGAGCGCGAGAGCCTGGAGGTGCGCATGCGCGAGGTGGAGGAGGAGAACCGCGCCCTCCGCAGGCAGCT CAGCCTGGCCCAGGGCCGAGCCCCATCCCATCGCCGAGGCAACCACTCCAAGACCTACTCCATGGAGGAGGGCACTGGAGACAGCGAGAA CCTTCGGGCTGGCATCGTGGCAGGCAACAGCTCCGAGTGTGGGCAGCAGCCGGTCGTGGAGAAATGCGAGACAATCCACGTTGCTATTGT CTGCGCCGGATACAATGCCAGCCGGGATGTCGTCACCCTGGTCAAATCCGTCCTGTTCCATAGACGGAACCCTCTGCACTTCCACCTTAT TGCTGACTCCATTGCGGAGCAGATCCTGGCCACGCTCTTCCAGACCTGGATGGTGCCCGCTGTGCGTGTGGACTTCTACAATGCAGACGA GCTCAAGTCTGAAGTTTCCTGGATCCCCAATAAACATTACTCTGGGATTTATGGTCTGATGAAGCTTGTCCTGACCAAGACTCTTCCTGC CAACCTGGAGAGAGTCATCGTCCTTGACACGGATATCACCTTTGCCACTGACATTGCAGAGCTGTGGGCTGTGTTCCACAAGTTCAAAGG TCAGCAAGTCCTGGGCTTGGTGGAGAACCAGAGTGACTGGTACCTTGGAAACCTGTGGAAAAATCACCGCCCATGGCCAGCCCTTGGAAG AGGCTACAACACAGGGGTGATCCTGTTACTTCTGGATAAGCTGCGGAAGATGAAATGGGAGCAGATGTGGAGGCTGACCGCAGAGAGGGA GCTCATGGGCATGCTCTCTACATCCTTAGCTGACCAGGATATTTTCAATGCCGTCATCAAACAAAACCCCTTCCTTGTGTACCAGCTCCC CTGCTTCTGGAATGTGCAGCTGTCAGACCACACCCGCTCCGAGCAGTGCTACAGAGACGTGTCTGATCTAAAGGTCATTCACTGGAACTC CCCCAAGAAGCTCCGGGTGAAGAACAAGCATGTGGAGTTTTTTCGCAACCTCTACCTGACCTTCCTGGAGTATGACGGCAATCTTCTGAG GCGGGAACTGTTTGGCTGCCCCAGTGAGGCTGATGTCAACAGTGAAAACCTCCAGAAGCAGCTGTCTGAGCTGGACGAGGACGACCTGTG CTATGAGTTCCGGCGAGAGCGCTTCACTGTCCACCGCACCCACCTGTACTTCCTGCACTACGAGTATGAGCCTGCAGCAGACAGCACGGA CGTCACCCTGGTCGCTCAGCTGTCCATGGACAGGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAG TTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAA GAAACCAACGCGGAGATGCTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAG GCCAGAACCGAGGAGCAGATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCC TCGCGCCTGCAGAAGTGGTTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAG GAACCCCTGAGCGCCCGCAGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCT GCCTTATCCGACTGGTACTCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTG TTCTTATTTCTAGCAATTCTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCT GAGCCCGTGGAACCTCCAAAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTC GGGAAGATGGCTGACATCCTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGG GCTGCCTTCCTGGCCTCCTGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGAT TTCATCTTTAAACGCTGCCCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAG GAGCGCTCCAGCGCCGCAGTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAG GAGGACGCCGGTCGCTTCCACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGTGTGC GAGAATGGCTGGCGCTGCTGCCTCATCAACAGGGACCGGAAGATGCCCACGGACTACATCAGGAACGGGGTGCTCTACGTCACGGAGAAT TACTTGTGCTTCGAAAGCTCCAAATCTGGGTCCTCAAAGAGGAACAAAGTCATCAAGCTAGTGGACATCACGGACATCCAGAAGTACAAG GTCCTGTCTGTCCTCCCAGGCTCAGGCATGGGGATTGCCGTGTCGACGCCATCCACCCAGAAACCGCTCGTGTTTGGTGCCATGGTGCAC AGGGATGAGGCCTTCGAGACCATTCTCAGCCAGTACATCAAGATCACCTCAGCGGCAGCGTCTGGCGGGGACAGCTAGTATTGACTTGCC CAGGACGTTGCTGGAATTTTCTTTTTCTTTTTCTTTTTCTTTTTTTTTTTTTACGATTTGGTAGTGGAAACAATTGGACATCCTCATGAG CTTTTGCAATAATTCTCCTGGACCTGTGGTTCTATTGTGTTGACCTCTGCGTTTTATCGACCAAGAAGGGGCCAGGGCTCACAGGGACGG GGGTGCCCCTCTCCCACAGGGCACGTCAGGTGCCTCTGAGGGCCACCCGCAGACTGGGGGAGGGGGCAGAGGCCCTCGGGGGCCCGTGGA GAAGACACACAGGACCCCTGGCCCTGCCCTTCTCCGTTCCAGCCTGGACAGAGAAACCTCTCCAGCCACCCCAAGAGGTTCTCGCAACCT TGTGTCCCGCTCTCCAGAGGCCAGAAGCTCGTCCACCACCAAAGCCATAGCTGAAGAGTGCGGGGCCCTTCCTCCTGGGGACAGAAAGAT GTCGTCAAGGAGGGACATGGGGGCCTTTCACCAACCACCGAGAAACGGGCCTGGCGGCCCTCCTTCCTCTTACATGAGACCCTCCTGTGG CATTTGCCCTTGGTGCCGGGCTGGGGCCGGGCGCAGTGACCCTGCCTGCGCTCCACACTCGCTCCACGGGAACAGAGAGGGTGAGAAGGG CCCACCCCTCGCCTGCCCTCAGTGTCTTTGGTGGCACCTTCCTTGCTGGCCTCCAGGGCGCTCAGCACCGCGTCTGTAAGGGCCTGCCTG CTGCTCTCGGCCTGACACGCCGGCCAGGAGGTCTGTAGCTGGGGACCAGTAAGGGCACAGGATGGTGCAGGTAAAAGCACATCTTTCTCA CACTTTGCTCTTTGGAAGGCCCAGGAGAACATCCGCGAAGGCTGTTGGAGGTGCTCCGAGCACTGTGGCATGTCTGGCACATGGCCCCCA GGCTGCGGTTGCCTGGGTTGGTTGGGGGAGGAAGTGGGGAGGAGTGTTCCGGGACCATGGTGGCCCAGGCTGCAGCCGCCTTTGGGCCAT CCGAGAGGCTCTGGCAGCCCCTGTGCTTTAGGGAGCAACCGTGAGCCGAGCCCAGAGGCCTGGGCCTGCACTGCCTGCAGCCGACATGCG ACAGCGTTCCCTCCCCCGCGTGCCTAGCCGGTGCCGGTCCGGGCACAGACCCCCCCAGCCCCCGCCCTGCCCCAGGGAAGCCTGGGCTTC CCGGGAACAAGGTGGCATTTGTGGAGGGAGCGCCCGCAGGCCTGGTCTGCTGGGGCCGCCTGCGCTGGGCTGAAGGGAGGGAAAGGCGGC TTGGGCCTCCTGGAAGGAGGTGGCCACCCCGCGGGCCTGCGTGTCTGCTGGGGCGGATCCCGCAGCTCCCTCAGCTTGTCCTGAGTCCCT TGGGTGTCGTTGAGATTGTTGTTTTTTGAAGAAACAGAAGATTCTATTTTTTACAGCGAGCAAGCTGGTTTTCTTATTTTTGTATCCTTT TTCAGATGTAATTTTTATCTTTGCTCCGATCCTCATTTGCTGGTGTGGGTGAGGGATCCGGCGGCATGGGCTGGTTTCACCCCCTTCACG AGGGGCCGCAGAGTCACACGCTGGTGCCGGGGGTGCTTTGGGGGGAGCTGCGCCGATCACCAGATTAAGCACATGTCCTATCCCAGGCGG TGGAGCGGAGCCCCCGTGGCTCTGGACTGCGCGGACGTTGGCGTCAGGATGACCACACGGCGGCCTTTCCCGAATGGGGACAGAACCCGC TCTGAGCCGTGGGTCTGGCTCCTGTAGGGGACTGGCTCTCTTGGTGCACCAGGGGAGGGGGACATATCCCAGTGAACCCCACCTTGGCGC CTGAGGCAACACAGGGTGGGCACTGACCCACCCCCAGGGGCGGCTGCAGAGGCAGTGCCCGCAGACAATGGCCACACCTCTCTCCCCAGG GCCCGGCAGTGCCCAAGGATGGGTCCGGGGCCTCGGGGCCAATGAGCGCCTCTTCCTAGGTGCTGGGATTCAGTCCCCAAACACAGCGGG AGGGGTCCCTGGGGCAGATGGGGCTTTACCAGCGTCGGGTGGTTTAGTTCGAGTCCCTTTTGTGGAGAAAGGGAGATGAAAACTGACCAC GTGCCAGGTGTGGCCGAAGCCCCCAGGGAGGGCCACATTCGGGGAGCGGGGGGTCGGGGGAGGGCCACCGACTGGCTCTGCTGCCAGCAC AGGCCCCTCCCTGGAAGTCCTCGGGAGCGGAGCGCGGATCGGCACGGGCTCTGGGCTCCCCGTGGAGAGAAGCTGTAGTTTTTACCAAAT TGTGTACATCTGGGCAGATGTTTAATTTCTGTGACTAATCACTGAACTAGACGAATGTTAAATTTTTTATGTCTGAAGCCTGAGTCTATT TTGGATCTGTAAATAATCATTGCCAGTGTGACTTTTGTTCAACAAAAGGATTGTACTGTATTAAGAACCGATGAAAAAAATTCTCCTGTA ACATTTTTTTAAGAAAACTTTGTTTGTTTAAAGAAAAAGTATTGTATAAATTATAATTTTTATTTAAATAAACCTAAAATGCTTTGTGCT >In-frame_LARGE_ENST00000437602_chr22_33712071_-_GRAMD4_ENST00000361034_chr22_47033737_+_5768nt GCAGTTAACTTATCCCGAAGCTCCAAAGCAAACGTCTTTTACTTCTTCGCCGGGGACGCTGCTGTACCACCGCTGCCTCCCTTTCGCATT CTGCTGGGCTCGGTCAGCCGCTGAGATTAGAGAGTATTATGAGGGAGGCCGAGGACTTCATGCTCCGGACAGAGAAACGGCGCTGGGATT AGGGATTGCCACTTCTGAGAGGATGCTGGGAATCTGCAGGGGGAGACGGAAATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCCCAGC CATCACCTGGATTTACCTGTTTTCTGGGAGCTTCGAAGATGGAAAGCCCGTGTCTCTGTCACCGCTGGAGTCCCAGGCACACAGCCCCAG GTACACGGCCTCCAGCCAGCGGGAGCGCGAGAGCCTGGAGGTGCGCATGCGCGAGGTGGAGGAGGAGAACCGCGCCCTCCGCAGGCAGCT CAGCCTGGCCCAGGGCCGAGCCCCATCCCATCGCCGAGGCAACCACTCCAAGACCTACTCCATGGAGGAGGGCACTGGAGACAGCGAGAA CCTTCGGGCTGGCATCGTGGCAGGCAACAGCTCCGAGTGTGGGCAGCAGCCGGTCGTGGAGAAATGCGAGACAATCCACGTTGCTATTGT CTGCGCCGGATACAATGCCAGCCGGGATGTCGTCACCCTGGTCAAATCCGTCCTGTTCCATAGACGGAACCCTCTGCACTTCCACCTTAT TGCTGACTCCATTGCGGAGCAGATCCTGGCCACGCTCTTCCAGACCTGGATGGTGCCCGCTGTGCGTGTGGACTTCTACAATGCAGACGA GCTCAAGTCTGAAGTTTCCTGGATCCCCAATAAACATTACTCTGGGATTTATGGTCTGATGAAGCTTGTCCTGACCAAGACTCTTCCTGC CAACCTGGAGAGAGTCATCGTCCTTGACACGGATATCACCTTTGCCACTGACATTGCAGAGCTGTGGGCTGTGTTCCACAAGTTCAAAGG TCAGCAAGTCCTGGGCTTGGTGGAGAACCAGAGTGACTGGTACCTTGGAAACCTGTGGAAAAATCACCGCCCATGGCCAGCCCTTGGAAG AGGCTACAACACAGGGGTGATCCTGTTACTTCTGGATAAGCTGCGGAAGATGAAATGGGAGCAGATGTGGAGGCTGACCGCAGAGAGGGA GCTCATGGGCATGCTCTCTACATCCTTAGCTGACCAGGATATTTTCAATGCCGTCATCAAACAAAACCCCTTCCTTGTGTACCAGCTCCC CTGCTTCTGGAATGTGCAGCTGTCAGACCACACCCGCTCCGAGCAGTGCTACAGAGACGTGTCTGATCTAAAGGTCATTCACTGGAACTC CCCCAAGAAGCTCCGGGTGAAGAACAAGCATGTGGAGTTTTTTCGCAACCTCTACCTGACCTTCCTGGAGTATGACGGCAATCTTCTGAG GCGGGAACTGTTTGGCTGCCCCAGTGAGGCTGATGTCAACAGTGAAAACCTCCAGAAGCAGCTGTCTGAGCTGGACGAGGACGACCTGTG CTATGAGTTCCGGCGAGAGCGCTTCACTGTCCACCGCACCCACCTGTACTTCCTGCACTACGAGTATGAGCCTGCAGCAGACAGCACGGA CGTCACCCTGGTCGCTCAGCTGTCCATGGACAGGCTGGTCCAGGGACCCTCATCATGGCCACAGGAGTCCAGGACTTTAACCGGACAGAG TTTGATCGACTGAATGAGATCAAAGGTCACCTGGAAATTGCCTTATTGGAAAAACATTTCTTACAGGAGGAGCTCCGGAAGCTGCGAGAA GAAACCAACGCGGAGATGCTGCGGCAGGAGCTGGACCGCGAGCGGCAGCGGCGGATGGAGCTGGAGCAGAAGGTGCAGGAGGTGCTGAAG GCCAGAACCGAGGAGCAGATGGCTCAGCAGCCCCCAAAAGGGCAGGCCCAGGCCAGCAATGGAGCAGAGCGCCGGAGCCAGGGGCTGTCC TCGCGCCTGCAGAAGTGGTTCTACGAGCGGTTTGGGGAGTACGTGGAGGACTTCCGGTTCCAGCCCGAGGAGAACACTGTGGAGACAGAG GAACCCCTGAGCGCCCGCAGGTTAACTGAAAATATGAGACGGCTCAAGCGCGGTGCCAAGCCGGTCACTAACTTTGTGAAGAACCTCTCT GCCTTATCCGACTGGTACTCCGTCTACACGTCTGCCATTGCCTTCACCGTGTACATGAATGCCGTGTGGCATGGCTGGGCCATCCCATTG TTCTTATTTCTAGCAATTCTGAGGTTATCCCTCAATTACCTCATCGCCAGGGGGTGGCGGATACAGTGGAGCATCGTGCCCGAAGTGTCT GAGCCCGTGGAACCTCCAAAGGAAGACCTGACTGTGTCTGAGAAGTTCCAGCTGGTGCTGGACGTCGCCCAGAAAGCCCAGAACCTTTTC GGGAAGATGGCTGACATCCTGGAGAAGATCAAGAACTTGTTCATGTGGGTCCAGCCGGAGATCACACAGAAGCTGTATGTGGCGCTCTGG GCTGCCTTCCTGGCCTCCTGCTTCTTCCCCTACCGCCTGGTGGGGCTTGCCGTGGGACTCTATGCTGGTATCAAGTTCTTCCTCATTGAT TTCATCTTTAAACGCTGCCCGAGGCTGCGCGCCAAGTACGACACGCCCTATATCATCTGGAGGAGTCTCCCCACCGACCCGCAGCTCAAG GAGCGCTCCAGCGCCGCAGTCTCACGCAGGCTGCAGACGACCTCGTCACGGAGCTACGTACCCAGCGCACCGGCCGGCCTGGGTAAAGAG GAGGACGCCGGTCGCTTCCACAGCACCAAGAAGGGCAATTTCCACGAGATCTTCAATCTGACAGAAAACGAGCGTCCGCTGGCGGTGTGC GAGAATGGCTGGCGCTGCTGCCTCATCAACAGGGACCGGAAGATGCCCACGGACTACATCAGGAACGGGGTGCTCTACGTCACGGAGAAT TACTTGTGCTTCGAAAGCTCCAAATCTGGGTCCTCAAAGAGGAACAAAGTCATCAAGCTAGTGGACATCACGGACATCCAGAAGTACAAG GTCCTGTCTGTCCTCCCAGGCTCAGGCATGGGGATTGCCGTGTCGACGCCATCCACCCAGAAACCGCTCGTGTTTGGTGCCATGGTGCAC AGGGATGAGGCCTTCGAGACCATTCTCAGCCAGTACATCAAGATCACCTCAGCGGCAGCGTCTGGCGGGGACAGCTAGTATTGACTTGCC CAGGACGTTGCTGGAATTTTCTTTTTCTTTTTCTTTTTCTTTTTTTTTTTTTACGATTTGGTAGTGGAAACAATTGGACATCCTCATGAG CTTTTGCAATAATTCTCCTGGACCTGTGGTTCTATTGTGTTGACCTCTGCGTTTTATCGACCAAGAAGGGGCCAGGGCTCACAGGGACGG GGGTGCCCCTCTCCCACAGGGCACGTCAGGTGCCTCTGAGGGCCACCCGCAGACTGGGGGAGGGGGCAGAGGCCCTCGGGGGCCCGTGGA GAAGACACACAGGACCCCTGGCCCTGCCCTTCTCCGTTCCAGCCTGGACAGAGAAACCTCTCCAGCCACCCCAAGAGGTTCTCGCAACCT TGTGTCCCGCTCTCCAGAGGCCAGAAGCTCGTCCACCACCAAAGCCATAGCTGAAGAGTGCGGGGCCCTTCCTCCTGGGGACAGAAAGAT GTCGTCAAGGAGGGACATGGGGGCCTTTCACCAACCACCGAGAAACGGGCCTGGCGGCCCTCCTTCCTCTTACATGAGACCCTCCTGTGG CATTTGCCCTTGGTGCCGGGCTGGGGCCGGGCGCAGTGACCCTGCCTGCGCTCCACACTCGCTCCACGGGAACAGAGAGGGTGAGAAGGG CCCACCCCTCGCCTGCCCTCAGTGTCTTTGGTGGCACCTTCCTTGCTGGCCTCCAGGGCGCTCAGCACCGCGTCTGTAAGGGCCTGCCTG CTGCTCTCGGCCTGACACGCCGGCCAGGAGGTCTGTAGCTGGGGACCAGTAAGGGCACAGGATGGTGCAGGTAAAAGCACATCTTTCTCA CACTTTGCTCTTTGGAAGGCCCAGGAGAACATCCGCGAAGGCTGTTGGAGGTGCTCCGAGCACTGTGGCATGTCTGGCACATGGCCCCCA GGCTGCGGTTGCCTGGGTTGGTTGGGGGAGGAAGTGGGGAGGAGTGTTCCGGGACCATGGTGGCCCAGGCTGCAGCCGCCTTTGGGCCAT CCGAGAGGCTCTGGCAGCCCCTGTGCTTTAGGGAGCAACCGTGAGCCGAGCCCAGAGGCCTGGGCCTGCACTGCCTGCAGCCGACATGCG ACAGCGTTCCCTCCCCCGCGTGCCTAGCCGGTGCCGGTCCGGGCACAGACCCCCCCAGCCCCCGCCCTGCCCCAGGGAAGCCTGGGCTTC CCGGGAACAAGGTGGCATTTGTGGAGGGAGCGCCCGCAGGCCTGGTCTGCTGGGGCCGCCTGCGCTGGGCTGAAGGGAGGGAAAGGCGGC TTGGGCCTCCTGGAAGGAGGTGGCCACCCCGCGGGCCTGCGTGTCTGCTGGGGCGGATCCCGCAGCTCCCTCAGCTTGTCCTGAGTCCCT TGGGTGTCGTTGAGATTGTTGTTTTTTGAAGAAACAGAAGATTCTATTTTTTACAGCGAGCAAGCTGGTTTTCTTATTTTTGTATCCTTT TTCAGATGTAATTTTTATCTTTGCTCCGATCCTCATTTGCTGGTGTGGGTGAGGGATCCGGCGGCATGGGCTGGTTTCACCCCCTTCACG AGGGGCCGCAGAGTCACACGCTGGTGCCGGGGGTGCTTTGGGGGGAGCTGCGCCGATCACCAGATTAAGCACATGTCCTATCCCAGGCGG TGGAGCGGAGCCCCCGTGGCTCTGGACTGCGCGGACGTTGGCGTCAGGATGACCACACGGCGGCCTTTCCCGAATGGGGACAGAACCCGC TCTGAGCCGTGGGTCTGGCTCCTGTAGGGGACTGGCTCTCTTGGTGCACCAGGGGAGGGGGACATATCCCAGTGAACCCCACCTTGGCGC CTGAGGCAACACAGGGTGGGCACTGACCCACCCCCAGGGGCGGCTGCAGAGGCAGTGCCCGCAGACAATGGCCACACCTCTCTCCCCAGG GCCCGGCAGTGCCCAAGGATGGGTCCGGGGCCTCGGGGCCAATGAGCGCCTCTTCCTAGGTGCTGGGATTCAGTCCCCAAACACAGCGGG AGGGGTCCCTGGGGCAGATGGGGCTTTACCAGCGTCGGGTGGTTTAGTTCGAGTCCCTTTTGTGGAGAAAGGGAGATGAAAACTGACCAC GTGCCAGGTGTGGCCGAAGCCCCCAGGGAGGGCCACATTCGGGGAGCGGGGGGTCGGGGGAGGGCCACCGACTGGCTCTGCTGCCAGCAC AGGCCCCTCCCTGGAAGTCCTCGGGAGCGGAGCGCGGATCGGCACGGGCTCTGGGCTCCCCGTGGAGAGAAGCTGTAGTTTTTACCAAAT TGTGTACATCTGGGCAGATGTTTAATTTCTGTGACTAATCACTGAACTAGACGAATGTTAAATTTTTTATGTCTGAAGCCTGAGTCTATT TTGGATCTGTAAATAATCATTGCCAGTGTGACTTTTGTTCAACAAAAGGATTGTACTGTATTAAGAACCGATGAAAAAAATTCTCCTGTA ACATTTTTTTAAGAAAACTTTGTTTGTTTAAAGAAAAAGTATTGTATAAATTATAATTTTTATTTAAATAAACCTAAAATGCTTTGTGCT 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FusionGenePPI for LARGE_GRAMD4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LARGE | PLAUR, TMEM25, SCGB2A2, SLAMF1, GAA, RANBP10 | GRAMD4 | APP, RBL2, TBC1D15 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LARGE_GRAMD4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LARGE_GRAMD4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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