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Fusion gene ID: 19415 |
FusionGeneSummary for LAMP1_F7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LAMP1_F7 | Fusion gene ID: 19415 | Hgene | Tgene | Gene symbol | LAMP1 | F7 | Gene ID | 3916 | 2155 |
| Gene name | lysosomal associated membrane protein 1 | coagulation factor VII | |
| Synonyms | CD107a|LAMPA|LGP120 | SPCA | |
| Cytomap | 13q34 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lysosome-associated membrane glycoprotein 1CD107 antigen-like family member ALAMP-1lysosome-associated membrane protein 1 | coagulation factor VIIFVII coagulation proteincoagulation factor VII (serum prothrombin conversion accelerator)eptacog alfaproconvertin | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | P11279 | P08709 | |
| Ensembl transtripts involved in fusion gene | ENST00000332556, ENST00000397181, ENST00000471046, | ENST00000541084, ENST00000346342, ENST00000375581, ENST00000473085, | |
| Fusion gene scores | * DoF score | 6 X 6 X 3=108 | 4 X 3 X 4=48 |
| # samples | 9 | 4 | |
| ** MAII score | log2(9/108*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: LAMP1 [Title/Abstract] AND F7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | F7 | GO:0002690 | positive regulation of leukocyte chemotaxis | 17991872 |
| Tgene | F7 | GO:0007596 | blood coagulation | 8632006|24998411 |
| Tgene | F7 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway | 17991872 |
| Tgene | F7 | GO:0016485 | protein processing | 24998411 |
| Tgene | F7 | GO:0050927 | positive regulation of positive chemotaxis | 17991872 |
| Tgene | F7 | GO:0051897 | positive regulation of protein kinase B signaling | 18612547 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-KF-A41W-01A | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000332556 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000332556 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000332556 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| 5CDS-3UTR | ENST00000332556 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| In-frame | ENST00000397181 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| 5CDS-3UTR | ENST00000397181 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000541084 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000346342 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3CDS | ENST00000471046 | ENST00000375581 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
| intron-3UTR | ENST00000471046 | ENST00000473085 | LAMP1 | chr13 | 113951810 | + | F7 | chr13 | 113768161 | + |
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FusionProtFeatures for LAMP1_F7 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LAMP1 | F7 |
| Presents carbohydrate ligands to selectins. Alsoimplicated in tumor cell metastasis. Acts as a receptor for Lassa virus protein.{ECO:0000269|PubMed:24970085}. | Initiates the extrinsic pathway of blood coagulation.Serine protease that circulates in the blood in a zymogen form.Factor VII is converted to factor VIIa by factor Xa, factor XIIa,factor IXa, or thrombin by minor proteolysis. In the presence oftissue factor and calcium ions, factor VIIa then converts factor Xto factor Xa by limited proteolysis. Factor VIIa will also convertfactor IX to factor IXa in the presence of tissue factor andcalcium. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | + | 2 | 8 | 106_142 | 83 | 445 | Domain | EGF-like 1%3B calcium-binding |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | + | 2 | 8 | 147_188 | 83 | 445 | Domain | EGF-like 2 |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | + | 2 | 8 | 213_452 | 83 | 445 | Domain | Peptidase S1 |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | + | 3 | 9 | 106_142 | 105 | 467 | Domain | EGF-like 1%3B calcium-binding |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | + | 3 | 9 | 147_188 | 105 | 467 | Domain | EGF-like 2 |
| Tgene | >F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | + | 3 | 9 | 213_452 | 105 | 467 | Domain | Peptidase S1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 195_227 | 20 | 418 | Region | Note=Hinge |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 228_382 | 20 | 418 | Region | Note=Second lumenal domain |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 29_194 | 20 | 418 | Region | Note=First lumenal domain |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 29_382 | 20 | 418 | Topological domain | Lumenal |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 406_417 | 20 | 418 | Topological domain | Cytoplasmic |
| Hgene | >LAMP1 | chr13:113951810 | chr13:113768161 | ENST00000332556 | + | 1 | 9 | 383_405 | 20 | 418 | Transmembrane | Helical |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000346342 | + | 2 | 8 | 61_105 | 83 | 445 | Domain | Gla |
| Tgene | F7 | chr13:113951810 | chr13:113768161 | ENST00000375581 | + | 3 | 9 | 61_105 | 105 | 467 | Domain | Gla |
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FusionGeneSequence for LAMP1_F7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_382aa MAAPGSARRPLLLLLLLLLLDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCH EGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLI AVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATAL ELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_1146nt ATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGC CAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAG GATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCAC GAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAAT GCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCT CAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATC GCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTC CCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAA CGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTG GAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAG TACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACG TGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_1448nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_2363nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG CATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGA CATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGAC AGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCC ACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAGTAGAGGCATGAACACACATGGATGCACACACAC ACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGATGGTCACACAGAGATACGCAAACACACCGATGCACAC GCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCACGCACATGCCAATGCACGCACACATCAGTGCACACGG ATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACACCG ATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCAC TTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCA AATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGCTTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCG >In-frame_LAMP1_ENST00000332556_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_3013nt GTGACAAGCGCTGCCGGCCGCGGTGTCTTCTTCGTGCCGGCGTCGCAGTGGCCGGGCCTCTTGCGTCTGGTAACGCCGCTGTCTCTAACG CCAGCCCTTGGCGCCCGCGCCCCGCCACCGCAGCGCCCGGCAGTCCGCGGCCCAACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCC GGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGCTACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTG CCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATATCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACT GTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGCGCT CCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCACAGTTGAATATCCATGTGGAAAAATACCTATTC TAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGT TGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACT GGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCC CCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCC TCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTG GCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCC CAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCC ACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCT CCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCC CTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGG CATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGA CATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGAC AGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCC ACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAGTAGAGGCATGAACACACATGGATGCACACACAC ACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGATGGTCACACAGAGATACGCAAACACACCGATGCACAC GCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCACGCACATGCCAATGCACGCACACATCAGTGCACACGG ATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACACCG ATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCAC TTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCA AATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGCTTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCG CACACCTGTGGTGCCTGCCACCCACTGGGTTGCCCATGATTCATTTTTGGAGCCCCCGGTGCTCATCCTCTGAGATGCTCTTTTCTTTCA CAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAACAAAAGCTGTTTGATAGATGTTTGAGGCTGTAGCTCC CAGGATCCTGTGGAATTGGATGTTCTCTCCCTGCCACAGCCCTTGTCAATGATATTTCACAGAGACCCTGGGAGCACCTGCTCAAGAGTC AGGGACACACGCATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGGACCTGGCAAGCTGCACTCTTGCTGAGTCCCCAGGGT GGTGGAAGAAGAATGAGAAACACATGAACAGAGAAATGGGGAGGTGACAAACAGTGCCCCCACTCAGACTCCGGCAAGCACGGCTCAGAG AGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGCACCACTGGCACTCACAGCAGCAAGGTGGGCACCATTGGCACTCACAGCAGCA AGGCAGGCACCAGCAACCCACCTCGGGGGCACTCAGGCATCATCTACTTCAGAGCAGACAGGGTCTATGAACTACAGCCGTGGGCTGCTT >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000541084_chr13_113768161_+_1304nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000346342_chr13_113768161_+_2219nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC CATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGAC AGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACA GAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGC CCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCCACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGA CAGTAGAGGCATGAACACACATGGATGCACACACACACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGAT GGTCACACAGAGATACGCAAACACACCGATGCACACGCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCAC GCACATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACAT GGATGAGCACACACACACCAATGCGCACACACACCGATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATG TGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCAC CATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCAAATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGC >In-frame_LAMP1_ENST00000397181_chr13_113951810_+_F7_ENST00000375581_chr13_113768161_+_2869nt ACCGCCGCCCGCGCCCCCGCTCCCCGCACCGTACCCGGCCGCCTCGCGCCATGGCGGCCCCCGGCAGCGCCCGGCGACCCCTGCTGCTGC TACTGCTGTTGCTGCTGCTCGATGGGGACCAGTGTGCCTCAAGTCCATGCCAGAATGGGGGCTCCTGCAAGGACCAGCTCCAGTCCTATA TCTGCTTCTGCCTCCCTGCCTTCGAGGGCCGGAACTGTGAGACGCACAAGGATGACCAGCTGATCTGTGTGAACGAGAACGGCGGCTGTG AGCAGTACTGCAGTGACCACACGGGCACCAAGCGCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACAC CCACAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCCAAGGCCGAATTGTGGGGGGCAAGGTGT GCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGTTGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGG TCTCCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCGAGCACGACCTCAGCGAGCACGACGGGG ATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCATCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGC ACCAGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTGAGAGGACGCTGGCCTTCGTGCGCTTCT CATTGGTCAGCGGCTGGGGCCAGCTGCTGGACCGTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGG ACTGCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTGCCGGCTACTCGGATGGCAGCAAGGACT CCTGCAAGGGGGACAGTGGAGGCCCACATGCCACCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCG CAACCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGCTCATGCGCTCAGAGCCACGCCCAGGAG TCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCAGCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCC CATATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAGGGAGGGAGAGGTGGGGAGGGAGACAGAGACAGAAACAGAGAGAGAC AGAGACAGAGAGAGACTGAGGGAGAGACTCTGAGGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACA GAGATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGTGCCAAGGTTGTCCTGGAGGCAGACAGC CCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAGCCCACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGA CAGTAGAGGCATGAACACACATGGATGCACACACACACACGCCAATGCACACACACAGAGATATGCACACACACGGATGCACACACAGAT GGTCACACAGAGATACGCAAACACACCGATGCACACGCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCAC GCACATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACACACCGATGTGCGCACACACAGATATGCACACACAT GGATGAGCACACACACACCAATGCGCACACACACCGATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATG TGTGCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCTTCACTTCAGACAATTCAGAAGCATCAC CATGCATGGTGGCGAATGCCCCCAAACTCTCCCCCAAATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGC TTCCCAGCTTCACAATAAACGGCTGCGTCTCCTCCGCACACCTGTGGTGCCTGCCACCCACTGGGTTGCCCATGATTCATTTTTGGAGCC CCCGGTGCTCATCCTCTGAGATGCTCTTTTCTTTCACAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAAC AAAAGCTGTTTGATAGATGTTTGAGGCTGTAGCTCCCAGGATCCTGTGGAATTGGATGTTCTCTCCCTGCCACAGCCCTTGTCAATGATA TTTCACAGAGACCCTGGGAGCACCTGCTCAAGAGTCAGGGACACACGCATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGG ACCTGGCAAGCTGCACTCTTGCTGAGTCCCCAGGGTGGTGGAAGAAGAATGAGAAACACATGAACAGAGAAATGGGGAGGTGACAAACAG TGCCCCCACTCAGACTCCGGCAAGCACGGCTCAGAGAGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGCACCACTGGCACTCACA GCAGCAAGGTGGGCACCATTGGCACTCACAGCAGCAAGGCAGGCACCAGCAACCCACCTCGGGGGCACTCAGGCATCATCTACTTCAGAG |
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FusionGenePPI for LAMP1_F7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| LAMP1 | TNFAIP3, SVIP, ELAVL1, ALG2, LAPTM5, ATP13A2, ATP6V1B1, ILF3, PTP4A1, TM9SF4, SDAD1, ILF2, UBL4A, FBXO6, AIP, HSD17B10, OSGEP, LGALS3, EPAS1, HNRNPA1, ZFPL1, EWSR1, NOTCH1, STK17B, SLC38A7, FZD7, RAB4A, FZD2, PLAA, C4A, LEMD3, LGALS1, ELP6, RARS, ORC4, DNM3, CUX1, FAM3C, ANAPC7, FAM207A | F7 | F3, F10, USP49, UIMC1, DMWD, ALB, RCHY1, CEP250, CEP76, VCP, FUS, USP7, C1QL1, NMU, CRELD2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for LAMP1_F7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | F7 | P08709 | DB00036 | Coagulation factor VIIa Recombinant Human | Coagulation factor VII | biotech | approved |
| Tgene | F7 | P08709 | DB00100 | Coagulation Factor IX (Recombinant) | Coagulation factor VII | biotech | approved|investigational |
| Tgene | F7 | P08709 | DB13151 | Anti-inhibitor coagulant complex | Coagulation factor VII | biotech | approved|investigational |
| Tgene | F7 | P08709 | DB00170 | Menadione | Coagulation factor VII | small molecule | approved|nutraceutical |
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RelatedDiseases for LAMP1_F7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | F7 | C0015503 | Factor VII Deficiency | 16 | CTD_human;HPO;ORPHANET;UNIPROT |
| Tgene | F7 | C0151699 | Intracranial Hemorrhages | 5 | CTD_human;HPO |
| Tgene | F7 | C0019080 | Hemorrhage | 3 | CTD_human |
| Tgene | F7 | C2937358 | Cerebral Hemorrhage | 2 | CTD_human |
| Tgene | F7 | C0012739 | Disseminated Intravascular Coagulation | 1 | CTD_human |
| Tgene | F7 | C0018965 | Hematuria | 1 | CTD_human |
| Tgene | F7 | C0019087 | Hemorrhagic Disorders | 1 | CTD_human |
| Tgene | F7 | C0032787 | Postoperative Complications | 1 | CTD_human |
| Tgene | F7 | C0040038 | Thromboembolism | 1 | CTD_human |
| Tgene | F7 | C0042487 | Venous Thrombosis | 1 | CTD_human |
| Tgene | F7 | C0273058 | Traumatic intracranial hemorrhage | 1 | CTD_human |
| Tgene | F7 | C0749098 | Hematoma, Subdural, Acute | 1 | CTD_human |
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