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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 19361

FusionGeneSummary for LAMA3_PSMA8

check button Fusion gene summary
Fusion gene informationFusion gene name: LAMA3_PSMA8
Fusion gene ID: 19361
HgeneTgene
Gene symbol

LAMA3

PSMA8

Gene ID

3910

143471

Gene namelaminin subunit alpha 4proteasome subunit alpha 8
SynonymsCMD1JJ|LAMA3|LAMA4*-1PSMA7L
Cytomap

6q21

18q11.2

Type of geneprotein-codingprotein-coding
Descriptionlaminin subunit alpha-4laminin alpha 4 chainlaminin, alpha 4proteasome subunit alpha-type 8proteasome subunit alpha type-7-likeproteasome (prosome, macropain) subunit, alpha type, 8proteasome subunit alpha type 7-like protein variant 1
Modification date2018052220180523
UniProtAcc

Q16787

Q8TAA3

Ensembl transtripts involved in fusion geneENST00000313654, ENST00000399516, 
ENST00000269217, ENST00000587184, 
ENST00000588770, 		ENST00000415576, 
ENST00000343848, ENST00000308268, 
Fusion gene scores* DoF score18 X 14 X 9=22682 X 2 X 2=8
# samples 232
** MAII scorelog2(23/2268*10)=-3.30171487399785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: LAMA3 [Title/Abstract] AND PSMA8 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-BH-A0H7-01ALAMA3chr18

21294036

+PSMA8chr18

23758794

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000313654ENST00000415576LAMA3chr18

21294036

+PSMA8chr18

23758794

+
In-frameENST00000313654ENST00000343848LAMA3chr18

21294036

+PSMA8chr18

23758794

+
In-frameENST00000313654ENST00000308268LAMA3chr18

21294036

+PSMA8chr18

23758794

+
In-frameENST00000399516ENST00000415576LAMA3chr18

21294036

+PSMA8chr18

23758794

+
In-frameENST00000399516ENST00000343848LAMA3chr18

21294036

+PSMA8chr18

23758794

+
In-frameENST00000399516ENST00000308268LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000269217ENST00000415576LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000269217ENST00000343848LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000269217ENST00000308268LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000587184ENST00000415576LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000587184ENST00000343848LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000587184ENST00000308268LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000588770ENST00000415576LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000588770ENST00000343848LAMA3chr18

21294036

+PSMA8chr18

23758794

+
intron-3CDSENST00000588770ENST00000308268LAMA3chr18

21294036

+PSMA8chr18

23758794

+

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FusionProtFeatures for LAMA3_PSMA8


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LAMA3

Q16787

PSMA8

Q8TAA3

Component of the spermatoproteasome, a form of theproteasome specifically found in testis that promotes degradationof histones, thereby participating actively to the exchange ofhistones during spermatogenesis. The proteasome is amulticatalytic proteinase complex which is characterized by itsability to cleave peptides with Arg, Phe, Tyr, Leu, and Gluadjacent to the leaving group at neutral or slightly basic pH (Bysimilarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751852_19411493334Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751987_21691493334Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752322_23881493334Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741852_19411493278Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741987_21691493278Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742322_23881493278Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371852_194101669Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371987_216901669Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372322_238801669Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751266_13111493334DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751312_13551493334DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751356_14041493334DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751405_14551493334DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751476_16531493334DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751687_17331493334DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751734_17861493334DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751787_18211493334DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752390_25911493334DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752598_27601493334DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752767_29271493334DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752986_31501493334DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275299_3551493334DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2753157_33301493334DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275356_4251493334DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275426_4691493334DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+27543_2981493334DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275491_5351493334DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275536_5881493334DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275590_6301493334DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275631_6831493334DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275684_7281493334DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741266_13111493278DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741312_13551493278DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741356_14041493278DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741405_14551493278DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741476_16531493278DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741687_17331493278DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741734_17861493278DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741787_18211493278DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742390_25911493278DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742598_27601493278DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742767_29271493278DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742986_31501493278DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274299_3551493278DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2743157_33301493278DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274356_4251493278DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274426_4691493278DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+27443_2981493278DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274491_5351493278DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274536_5881493278DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274590_6301493278DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274631_6831493278DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274684_7281493278DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371266_131101669DomainLaminin EGF-like 9
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371312_135501669DomainLaminin EGF-like 10
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371356_140401669DomainLaminin EGF-like 11
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371405_145501669DomainLaminin EGF-like 12
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371476_165301669DomainLaminin IV type A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371687_173301669DomainLaminin EGF-like 13
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371734_178601669DomainLaminin EGF-like 14
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371787_182101669DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372390_259101669DomainLaminin G-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372598_276001669DomainLaminin G-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372767_292701669DomainLaminin G-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372986_315001669DomainLaminin G-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137299_35501669DomainLaminin EGF-like 1
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1373157_333001669DomainLaminin G-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137356_42501669DomainLaminin EGF-like 2
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137426_46901669DomainLaminin EGF-like 3
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+13743_29801669DomainLaminin N-terminal
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137491_53501669DomainLaminin EGF-like 4
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137536_58801669DomainLaminin EGF-like 5
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137590_63001669DomainLaminin EGF-like 6
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137631_68301669DomainLaminin EGF-like 7
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137684_72801669DomainLaminin EGF-like 8
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2752278_22801493334MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2742278_22801493278MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1372278_228001669MotifCell attachment site
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751266_14651493334RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751654_18211493334RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+2751822_23891493334RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275298_7281493334RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:23758794ENST00000313654+275796_12651493334RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741266_14651493278RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741654_18211493278RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+2741822_23891493278RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274298_7281493278RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:23758794ENST00000399516+274796_12651493278RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371266_146501669RegionNote=Domain III B
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371654_182101669RegionNote=Domain III A
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+1371822_238901669RegionNote=Domain II and I
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137298_72801669RegionNote=Domain V
HgeneLAMA3chr18:21294036chr18:23758794ENST00000587184+137796_126501669RegionNote=Domain IV 1 (domain IV B)


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FusionGeneSequence for LAMA3_PSMA8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_241aa
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQANAIGRSAKTVREFLEKNYTEDAIASDSEAI


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_723nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_1377nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCAAATGCAATAGGCCGAAGTGCTAAAACTGT
TCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATCAAGTTAGCAATAAAAGCTTTGCTAGAAGT
TGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAGATGTTTAGTGCAAAAGAAGTTGAATTATA
TGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTCTAATTCTTAGGATGACCACTGGGAGGTCT
TAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTTATTTTGCAGCATTACATGCAGTACTTGTG
TGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGGTTTATGTGAAGATTTTCTTTGAAAGGGGA
TTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCCAGTGTCTTACTTACCTTCATATATGCAAA
TATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTGACTGTCAGTTAAGGACATAGCTATTCCAA

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_1908nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCAAATGCAATAGGCCGAAGTGCTAAAACTGT
TCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATCAAGTTAGCAATAAAAGCTTTGCTAGAAGT
TGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAGATGTTTAGTGCAAAAGAAGTTGAATTATA
TGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTCTAATTCTTAGGATGACCACTGGGAGGTCT
TAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTTATTTTGCAGCATTACATGCAGTACTTGTG
TGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGGTTTATGTGAAGATTTTCTTTGAAAGGGGA
TTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCCAGTGTCTTACTTACCTTCATATATGCAAA
TATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTGACTGTCAGTTAAGGACATAGCTATTCCAA
ATAAACTAAATATAATATTGAGCTGCATTTCTCAAAGAATGACAAAAGCATCCTTATACTGATGAGTTCTTAAAATTTTGTCAGAGCCTT
CTTCATTTTACAATATTTTGTTATTTTTATTTTACCTTTTTCATTTTACAATATTTCGTTATTTTTATTTTACCTTTTTCATTTTACAAG
TTGCAATATATTGTTTCGTTCATGGAACAAATATAGGCTGAATTCAAACATGCAATTAAAGCATGGGAAGAGCTTCTAAGGGCATCTTAA
CAGGATGCTACATGAAAATAAGGAAAGAAATTAATACATATCACTTTTAGTTTAGATTTTTATTTTATCTCAAGTATGTCCAGTGTGTTC
GGTTTGTTACATATTCCATGAAATATCTGAGTGTGTATTTTATGATTGGTATTATGGAAGGCTTATTGGGGGAACAAGAAAAATATAAAA
AGTGATCTCTGCCCACGGAAAGGATTTAATCCAAATGGTCCACAAGAGGAATGTGCTTAATTCCTACAGTGAGTTTATATTTTTGAAAAT

>In-frame_LAMA3_ENST00000313654_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_1908nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCAAATGCAATAGGCCGAAGTGCTAAAACTGT
TCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATCAAGTTAGCAATAAAAGCTTTGCTAGAAGT
TGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAGATGTTTAGTGCAAAAGAAGTTGAATTATA
TGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTCTAATTCTTAGGATGACCACTGGGAGGTCT
TAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTTATTTTGCAGCATTACATGCAGTACTTGTG
TGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGGTTTATGTGAAGATTTTCTTTGAAAGGGGA
TTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCCAGTGTCTTACTTACCTTCATATATGCAAA
TATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTGACTGTCAGTTAAGGACATAGCTATTCCAA
ATAAACTAAATATAATATTGAGCTGCATTTCTCAAAGAATGACAAAAGCATCCTTATACTGATGAGTTCTTAAAATTTTGTCAGAGCCTT
CTTCATTTTACAATATTTTGTTATTTTTATTTTACCTTTTTCATTTTACAATATTTCGTTATTTTTATTTTACCTTTTTCATTTTACAAG
TTGCAATATATTGTTTCGTTCATGGAACAAATATAGGCTGAATTCAAACATGCAATTAAAGCATGGGAAGAGCTTCTAAGGGCATCTTAA
CAGGATGCTACATGAAAATAAGGAAAGAAATTAATACATATCACTTTTAGTTTAGATTTTTATTTTATCTCAAGTATGTCCAGTGTGTTC
GGTTTGTTACATATTCCATGAAATATCTGAGTGTGTATTTTATGATTGGTATTATGGAAGGCTTATTGGGGGAACAAGAAAAATATAAAA
AGTGATCTCTGCCCACGGAAAGGATTTAATCCAAATGGTCCACAAGAGGAATGTGCTTAATTCCTACAGTGAGTTTATATTTTTGAAAAT

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000415576_chr18_23758794_+_1136nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC
TAATTCTTAGGATGACCACTGGGAGGTCTTAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTT
ATTTTGCAGCATTACATGCAGTACTTGTGTGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGG
TTTATGTGAAGATTTTCTTTGAAAGGGGATTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCC
AGTGTCTTACTTACCTTCATATATGCAAATATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTG

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000343848_chr18_23758794_+_1667nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC
TAATTCTTAGGATGACCACTGGGAGGTCTTAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTT
ATTTTGCAGCATTACATGCAGTACTTGTGTGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGG
TTTATGTGAAGATTTTCTTTGAAAGGGGATTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCC
AGTGTCTTACTTACCTTCATATATGCAAATATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTG
ACTGTCAGTTAAGGACATAGCTATTCCAAATAAACTAAATATAATATTGAGCTGCATTTCTCAAAGAATGACAAAAGCATCCTTATACTG
ATGAGTTCTTAAAATTTTGTCAGAGCCTTCTTCATTTTACAATATTTTGTTATTTTTATTTTACCTTTTTCATTTTACAATATTTCGTTA
TTTTTATTTTACCTTTTTCATTTTACAAGTTGCAATATATTGTTTCGTTCATGGAACAAATATAGGCTGAATTCAAACATGCAATTAAAG
CATGGGAAGAGCTTCTAAGGGCATCTTAACAGGATGCTACATGAAAATAAGGAAAGAAATTAATACATATCACTTTTAGTTTAGATTTTT
ATTTTATCTCAAGTATGTCCAGTGTGTTCGGTTTGTTACATATTCCATGAAATATCTGAGTGTGTATTTTATGATTGGTATTATGGAAGG
CTTATTGGGGGAACAAGAAAAATATAAAAAGTGATCTCTGCCCACGGAAAGGATTTAATCCAAATGGTCCACAAGAGGAATGTGCTTAAT

>In-frame_LAMA3_ENST00000399516_chr18_21294036_+_PSMA8_ENST00000308268_chr18_23758794_+_1667nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGGCA
AATGCAATAGGCCGAAGTGCTAAAACTGTTCGAGAATTTCTAGAAAAGAATTACACAGAAGATGCCATAGCAAGTGACAGTGAAGCTATC
AAGTTAGCAATAAAAGCTTTGCTAGAAGTTGTCCAGTCTGGTGGAAAAAACATTGAACTTGCTATAATAAGAAGAAATCAACCTTTGAAG
ATGTTTAGTGCAAAAGAAGTTGAATTATATGTAACTGAAATAGAAAAGGAAAAGGAAGAAGCAGAGAAGAAAAAATCAAAGAAATCTGTC
TAATTCTTAGGATGACCACTGGGAGGTCTTAATGTTTTGTTTTATTGTACTGCCTGAGGTTGTTTAGTGAAATTTTAGAGGAAAACAGTT
ATTTTGCAGCATTACATGCAGTACTTGTGTGATGTTTTGAGAATGCCAGATCTGTGGCTGTCTTCATTCTATTACATAGTCAAACATAGG
TTTATGTGAAGATTTTCTTTGAAAGGGGATTTCAGTAATTGTTGAGAGCAGTCATAATTCCACATAAGCCTGAGACTCTATAATTTGTCC
AGTGTCTTACTTACCTTCATATATGCAAATATAATTTTAAAAAATTTTTTAATTAAAAAAATTTAATAATTTGGTGATGTTTGAATATTG
ACTGTCAGTTAAGGACATAGCTATTCCAAATAAACTAAATATAATATTGAGCTGCATTTCTCAAAGAATGACAAAAGCATCCTTATACTG
ATGAGTTCTTAAAATTTTGTCAGAGCCTTCTTCATTTTACAATATTTTGTTATTTTTATTTTACCTTTTTCATTTTACAATATTTCGTTA
TTTTTATTTTACCTTTTTCATTTTACAAGTTGCAATATATTGTTTCGTTCATGGAACAAATATAGGCTGAATTCAAACATGCAATTAAAG
CATGGGAAGAGCTTCTAAGGGCATCTTAACAGGATGCTACATGAAAATAAGGAAAGAAATTAATACATATCACTTTTAGTTTAGATTTTT
ATTTTATCTCAAGTATGTCCAGTGTGTTCGGTTTGTTACATATTCCATGAAATATCTGAGTGTGTATTTTATGATTGGTATTATGGAAGG
CTTATTGGGGGAACAAGAAAAATATAAAAAGTGATCTCTGCCCACGGAAAGGATTTAATCCAAATGGTCCACAAGAGGAATGTGCTTAAT


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FusionGenePPI for LAMA3_PSMA8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
LAMA3SDC2, APC, SIRT1, TUBG1, TSHR, TAZ, PTPRK, PLG, PLAT, SPINK4, CD44, DEFA1, SCGB2A2, GML, SCGB1D4, SLAMF1PSMA8XBP1, MDM2, PSMB6, PSMB7, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMB1, PSMB5, PSMB3, PSMB8, PSMB2, PSMB4, PSMC2, PSMC6, PSMA7, PSMD7, PSMD8, PSMC4, PSMC1, PSMD2, PSMC3, PSMC5, PSMD6, PSME3, PSMD14, PSMD3, PSMD13, VIM, PSMB9, PSMD1, MCM2, TSC22D2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for LAMA3_PSMA8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LAMA3_PSMA8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneLAMA3C0027339Nail Diseases1CTD_human
HgeneLAMA3C0037299Skin Ulcer1CTD_human;HPO
HgeneLAMA3C0079301Junctional Epidermolysis Bullosa1CTD_human
HgeneLAMA3C1328355Laryngoonychocutaneous syndrome1CTD_human;ORPHANET