FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 188

FusionGeneSummary for ABCF1_SHC2

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCF1_SHC2
Fusion gene ID: 188
HgeneTgene
Gene symbol

ABCF1

SHC2

Gene ID

23

25759

Gene nameATP binding cassette subfamily F member 1SHC adaptor protein 2
SynonymsABC27|ABC50SCK|SHCB|SLI
Cytomap

6p21.33

19p13.3

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family F member 1ATP-binding cassette 50 (TNF-alpha stimulated)ATP-binding cassette, sub-family F (GCN20), member 1TNF-alpha-stimulated ABC proteinTNFalpha-inducible ATP-binding proteinSHC-transforming protein 2SH2 domain protein C2SHC (Src homology 2 domain containing) transforming protein 2SHC-transforming protein Bneuronal Shc adaptor homologprotein Scksrc homology 2 domain-containing-transforming protein C2
Modification date2018051920180523
UniProtAcc

Q8NE71

P98077

Ensembl transtripts involved in fusion geneENST00000326195, ENST00000376545, 
ENST00000396515, ENST00000457111, 
ENST00000452530, ENST00000416932, 
ENST00000470464, ENST00000419893, 
ENST00000448939, ENST00000457970, 
ENST00000475528, ENST00000457078, 
ENST00000412443, ENST00000546690, 
ENST00000421608, ENST00000486105, 
ENST00000383588, ENST00000383587, 
ENST00000400609, ENST00000485585, 
ENST00000426219, ENST00000421042, 
ENST00000552867, ENST00000454094, 
ENST00000494413, ENST00000423247, 
ENST00000420257, ENST00000456791, 
ENST00000495194, 		ENST00000264554, 
Fusion gene scores* DoF score4 X 4 X 3=484 X 3 X 4=48
# samples 54
** MAII scorelog2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCF1 [Title/Abstract] AND SHC2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLGGTCGA-TM-A7CF-01AABCF1chr6

30554488

+SHC2chr19

440932

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000326195ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
In-frameENST00000376545ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000396515ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000457111ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000452530ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000416932ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000470464ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000419893ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000448939ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000457970ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000475528ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000457078ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000412443ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000546690ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000421608ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000486105ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000383588ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000383587ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000400609ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000485585ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000426219ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000421042ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000552867ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000454094ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000494413ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000423247ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000420257ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000456791ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-
intron-3CDSENST00000495194ENST00000264554ABCF1chr6

30554488

+SHC2chr19

440932

-

Top

FusionProtFeatures for ABCF1_SHC2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABCF1

Q8NE71

SHC2

P98077

Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved inthe ribosome biogenesis. {ECO:0000269|PubMed:19570978}. Signaling adapter that couples activated growth factorreceptors to signaling pathway in neurons. Involved in the signaltransduction pathways of neurotrophin-activated Trk receptors incortical neurons (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCF1chr6:30554488chr19:440932ENST00000326195+2025141_243677846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000376545+1924141_243639808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000326195+2025304_548677846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000376545+1924304_548639808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000326195+2025336_343677846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000326195+2025658_665677846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000376545+1924336_343639808Nucleotide bindingATP 1
TgeneSHC2chr6:30554488chr19:440932ENST00000264554-013487_578156694DomainSH2
TgeneSHC2chr6:30554488chr19:440932ENST00000264554-013330_486156694RegionNote=CH1

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCF1chr6:30554488chr19:440932ENST00000383587+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000383588+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000412443+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000419893+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000420257+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000421042+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000423247+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000426219+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000448939+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000452530+124141_243-32808Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000457078+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000457111+125141_243-38846Compositional biasNote=Glu-rich
HgeneABCF1chr6:30554488chr19:440932ENST00000326195+2025625_840677846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000376545+1924625_840639808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000383587+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000383587+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000383588+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000383588+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000412443+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000412443+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000419893+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000419893+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000420257+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000420257+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000421042+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000421042+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000423247+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000423247+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000426219+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000426219+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000448939+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000448939+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000452530+124304_548-32808DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000452530+124625_840-32808DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000457078+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000457078+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000457111+125304_548-38846DomainABC transporter 1
HgeneABCF1chr6:30554488chr19:440932ENST00000457111+125625_840-38846DomainABC transporter 2
HgeneABCF1chr6:30554488chr19:440932ENST00000376545+1924658_665639808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000383587+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000383587+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000383588+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000383588+125658_665-38846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000412443+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000412443+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000419893+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000419893+125658_665-38846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000420257+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000420257+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000421042+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000421042+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000423247+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000423247+125658_665-38846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000426219+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000426219+125658_665-38846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000448939+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000448939+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000452530+124336_343-32808Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000452530+124658_665-32808Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000457078+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000457078+125658_665-38846Nucleotide bindingATP 2
HgeneABCF1chr6:30554488chr19:440932ENST00000457111+125336_343-38846Nucleotide bindingATP 1
HgeneABCF1chr6:30554488chr19:440932ENST00000457111+125658_665-38846Nucleotide bindingATP 2
TgeneSHC2chr6:30554488chr19:440932ENST00000264554-013147_329156694DomainPID


Top

FusionGeneSequence for ABCF1_SHC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ABCF1_ENST00000326195_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_677aa
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDD
DGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKE
EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEKKKLKKQMEYERQ
VASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQ
KFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGV

>In-frame_ABCF1_ENST00000376545_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_639aa
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDD
DGEEKELMERLKKLSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKE
EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEK
FSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQ
GQLEQGDDTAAERLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVI
WLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEA
LTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ABCF1_ENST00000326195_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_2031nt
ATGCCGAAGGCGCCCAAGCAGCAGCCGCCGGAGCCCGAGTGGATCGGGGACGGAGAGAGCACGAGCCCATCAGACAAAGTGGTGAAGAAA
GGGAAGAAGGACAAGAAGATCAAAAAAACGTTCTTTGAAGAGCTGGCAGTAGAAGATAAACAGGCTGGGGAAGAAGAGAAAGTGCTCAAG
GAGAAGGAGCAGCAGCAGCAGCAACAGCAACAGCAGCAAAAAAAAAAGCGAGATACCCGAAAAGGCAGGCGGAAGAAGGATGTGGATGAT
GATGGAGAAGAGAAAGAGCTCATGGAGCGTCTTAAGAAGCTCTCAGTGCCAACCAGTGATGAGGAGGATGAAGTACCCGCCCCAAAACCC
CGCGGAGGGAAGAAAACCAAGGGTGGTAATGTTTTTGCAGCCCTGATTCAGGATCAGAGTGAGGAAGAGGAGGAGGAAGAAAAACATCCT
CCTAAGCCTGCCAAGCCGGAGAAGAATCGGATCAATAAGGCCGTATCTGAGGAACAGCAGCCTGCACTCAAGGGCAAAAAGGGAAAGGAA
GAGAAGTCAAAAGGGAAGGCTAAGCCTCAAAATAAATTCGCTGCTCTGGACAATGAAGAGGAGGATAAAGAAGAAGAAATTATAAAGGAA
AAGGAGCCTCCCAAACAAGGGAAGGAGAAGGCCAAGAAGGCAGAGCAGGGTTCAGAGGAAGAAGGAGAAGGGGAAGAAGAGGAGGAGGAA
GGAGGAGAGTCTAAGGCAGATGATCCCTATGCTCATCTTAGCAAAAAGGAGAAGAAAAAGCTGAAAAAACAGATGGAGTATGAGCGCCAA
GTGGCTTCATTAAAAGCAGCCAATGCAGCTGAAAATGACTTCTCCGTGTCCCAGGCGGAGATGTCCTCCCGCCAAGCCATGTTAGAAAAT
GCATCTGACATCAAGCTGGAGAAGTTCAGCATCTCCGCTCATGGCAAGGAGCTGTTCGTCAATGCAGACCTGTACATTGTAGCCGGCCGC
CGCTACGGGCTGGTAGGACCCAATGGCAAGGGCAAGACCACACTCCTCAAGCACATTGCCAACCGAGCCCTGAGCATCCCTCCCAACATT
GATGTGTTGCTGTGTGAGCAGGAGGTGGTAGCAGATGAGACACCAGCAGTCCAGGCTGTTCTTCGAGCTGACACCAAGCGATTGAAGCTG
CTGGAAGAGGAGCGGCGGCTTCAGGGACAGCTGGAACAAGGGGATGACACAGCTGCTGAGAGGCTAGAGAAGGTGTATGAGGAATTGCGG
GCCACTGGGGCGGCAGCTGCAGAGGCCAAAGCACGGCGGATCCTGGCTGGCCTGGGCTTTGACCCTGAAATGCAGAATCGACCCACACAG
AAGTTCTCAGGGGGCTGGCGCATGCGTGTCTCCCTGGCCAGGGCACTGTTCATGGAGCCCACACTGCTGATGCTGGATGAGCCCACCAAC
CACCTGGACCTCAACGCTGTCATCTGGCTTAATAACTACCTCCAGGGCTGGCGGAAGACCTTGCTGATCGTCTCCCATGACCAGGGCTTC
TTGGATGATGTCTGCACTGATATCATCCACCTCGATGCCCAGCGGCTCCACTACTATAGGGGCAATTACATGACCTTCAAAAAGATGTAC
CAGCAGAAGCAGAAAGAACTGCTGAAACAGTATGAGAAGCAAGAGAAAAAGCTGAAGGAGCTGAAGGCAGGCGGGAAGTCCACCAAGCAG
GCGGAAAAACAAACGAAGGAAGCCCTGACTCGGAAGCAGCAGAAATGCCGACGGAAAAACCAAGATGAGGAATCCCAGGAGGCCCCTGAG
CTCCTGAAGCGCCCTAAGGAGTACACTGTGCGCTTCACTTTTCCAGACCCCCCACCACTCAGCCCTCCAGTGCTGGGTCTGCATGGTGTG
ACATTCGGCTACCAGGGACAGAAACCACTCTTTAAGAACTTGGATTTTGGCATCGACATGGATTCAAGGATTTGCATTGTGGGCCCTAAT

>In-frame_ABCF1_ENST00000376545_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_1917nt
ATGCCGAAGGCGCCCAAGCAGCAGCCGCCGGAGCCCGAGTGGATCGGGGACGGAGAGAGCACGAGCCCATCAGACAAAGTGGTGAAGAAA
GGGAAGAAGGACAAGAAGATCAAAAAAACGTTCTTTGAAGAGCTGGCAGTAGAAGATAAACAGGCTGGGGAAGAAGAGAAAGTGCTCAAG
GAGAAGGAGCAGCAGCAGCAGCAACAGCAACAGCAGCAAAAAAAAAAGCGAGATACCCGAAAAGGCAGGCGGAAGAAGGATGTGGATGAT
GATGGAGAAGAGAAAGAGCTCATGGAGCGTCTTAAGAAGCTCTCAGTGCCAACCAGTGATGAGGAGGATGAAGTACCCGCCCCAAAACCC
CGCGGAGGGAAGAAAACCAAGGGTGGTAATGTTTTTGCAGCCCTGATTCAGGATCAGAGTGAGGAAGAGGAGGAGGAAGAAAAACATCCT
CCTAAGCCTGCCAAGCCGGAGAAGAATCGGATCAATAAGGCCGTATCTGAGGAACAGCAGCCTGCACTCAAGGGCAAAAAGGGAAAGGAA
GAGAAGTCAAAAGGGAAGGCTAAGCCTCAAAATAAATTCGCTGCTCTGGACAATGAAGAGGAGGATAAAGAAGAAGAAATTATAAAGGAA
AAGGAGCCTCCCAAACAAGGGAAGGAGAAGGCCAAGAAGGCAGAGCAGATGGAGTATGAGCGCCAAGTGGCTTCATTAAAAGCAGCCAAT
GCAGCTGAAAATGACTTCTCCGTGTCCCAGGCGGAGATGTCCTCCCGCCAAGCCATGTTAGAAAATGCATCTGACATCAAGCTGGAGAAG
TTCAGCATCTCCGCTCATGGCAAGGAGCTGTTCGTCAATGCAGACCTGTACATTGTAGCCGGCCGCCGCTACGGGCTGGTAGGACCCAAT
GGCAAGGGCAAGACCACACTCCTCAAGCACATTGCCAACCGAGCCCTGAGCATCCCTCCCAACATTGATGTGTTGCTGTGTGAGCAGGAG
GTGGTAGCAGATGAGACACCAGCAGTCCAGGCTGTTCTTCGAGCTGACACCAAGCGATTGAAGCTGCTGGAAGAGGAGCGGCGGCTTCAG
GGACAGCTGGAACAAGGGGATGACACAGCTGCTGAGAGGCTAGAGAAGGTGTATGAGGAATTGCGGGCCACTGGGGCGGCAGCTGCAGAG
GCCAAAGCACGGCGGATCCTGGCTGGCCTGGGCTTTGACCCTGAAATGCAGAATCGACCCACACAGAAGTTCTCAGGGGGCTGGCGCATG
CGTGTCTCCCTGGCCAGGGCACTGTTCATGGAGCCCACACTGCTGATGCTGGATGAGCCCACCAACCACCTGGACCTCAACGCTGTCATC
TGGCTTAATAACTACCTCCAGGGCTGGCGGAAGACCTTGCTGATCGTCTCCCATGACCAGGGCTTCTTGGATGATGTCTGCACTGATATC
ATCCACCTCGATGCCCAGCGGCTCCACTACTATAGGGGCAATTACATGACCTTCAAAAAGATGTACCAGCAGAAGCAGAAAGAACTGCTG
AAACAGTATGAGAAGCAAGAGAAAAAGCTGAAGGAGCTGAAGGCAGGCGGGAAGTCCACCAAGCAGGCGGAAAAACAAACGAAGGAAGCC
CTGACTCGGAAGCAGCAGAAATGCCGACGGAAAAACCAAGATGAGGAATCCCAGGAGGCCCCTGAGCTCCTGAAGCGCCCTAAGGAGTAC
ACTGTGCGCTTCACTTTTCCAGACCCCCCACCACTCAGCCCTCCAGTGCTGGGTCTGCATGGTGTGACATTCGGCTACCAGGGACAGAAA
CCACTCTTTAAGAACTTGGATTTTGGCATCGACATGGATTCAAGGATTTGCATTGTGGGCCCTAATGGTGTGGGGAAGAGTACGCTACTC


* Fusion transcript sequences (Full-length transcript).
>In-frame_ABCF1_ENST00000326195_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_4169nt
CGGGGGCGGGGTTGGCCGCGCCAGCTTGGAGAGCCAGCCCCATCGGGGTTCCCCGCCGCCGGAAGCGGAAATAGCACCGGGCGCCGCCAC
AGTAGCTGTAACTGCCACCGCGATGCCGAAGGCGCCCAAGCAGCAGCCGCCGGAGCCCGAGTGGATCGGGGACGGAGAGAGCACGAGCCC
ATCAGACAAAGTGGTGAAGAAAGGGAAGAAGGACAAGAAGATCAAAAAAACGTTCTTTGAAGAGCTGGCAGTAGAAGATAAACAGGCTGG
GGAAGAAGAGAAAGTGCTCAAGGAGAAGGAGCAGCAGCAGCAGCAACAGCAACAGCAGCAAAAAAAAAAGCGAGATACCCGAAAAGGCAG
GCGGAAGAAGGATGTGGATGATGATGGAGAAGAGAAAGAGCTCATGGAGCGTCTTAAGAAGCTCTCAGTGCCAACCAGTGATGAGGAGGA
TGAAGTACCCGCCCCAAAACCCCGCGGAGGGAAGAAAACCAAGGGTGGTAATGTTTTTGCAGCCCTGATTCAGGATCAGAGTGAGGAAGA
GGAGGAGGAAGAAAAACATCCTCCTAAGCCTGCCAAGCCGGAGAAGAATCGGATCAATAAGGCCGTATCTGAGGAACAGCAGCCTGCACT
CAAGGGCAAAAAGGGAAAGGAAGAGAAGTCAAAAGGGAAGGCTAAGCCTCAAAATAAATTCGCTGCTCTGGACAATGAAGAGGAGGATAA
AGAAGAAGAAATTATAAAGGAAAAGGAGCCTCCCAAACAAGGGAAGGAGAAGGCCAAGAAGGCAGAGCAGGGTTCAGAGGAAGAAGGAGA
AGGGGAAGAAGAGGAGGAGGAAGGAGGAGAGTCTAAGGCAGATGATCCCTATGCTCATCTTAGCAAAAAGGAGAAGAAAAAGCTGAAAAA
ACAGATGGAGTATGAGCGCCAAGTGGCTTCATTAAAAGCAGCCAATGCAGCTGAAAATGACTTCTCCGTGTCCCAGGCGGAGATGTCCTC
CCGCCAAGCCATGTTAGAAAATGCATCTGACATCAAGCTGGAGAAGTTCAGCATCTCCGCTCATGGCAAGGAGCTGTTCGTCAATGCAGA
CCTGTACATTGTAGCCGGCCGCCGCTACGGGCTGGTAGGACCCAATGGCAAGGGCAAGACCACACTCCTCAAGCACATTGCCAACCGAGC
CCTGAGCATCCCTCCCAACATTGATGTGTTGCTGTGTGAGCAGGAGGTGGTAGCAGATGAGACACCAGCAGTCCAGGCTGTTCTTCGAGC
TGACACCAAGCGATTGAAGCTGCTGGAAGAGGAGCGGCGGCTTCAGGGACAGCTGGAACAAGGGGATGACACAGCTGCTGAGAGGCTAGA
GAAGGTGTATGAGGAATTGCGGGCCACTGGGGCGGCAGCTGCAGAGGCCAAAGCACGGCGGATCCTGGCTGGCCTGGGCTTTGACCCTGA
AATGCAGAATCGACCCACACAGAAGTTCTCAGGGGGCTGGCGCATGCGTGTCTCCCTGGCCAGGGCACTGTTCATGGAGCCCACACTGCT
GATGCTGGATGAGCCCACCAACCACCTGGACCTCAACGCTGTCATCTGGCTTAATAACTACCTCCAGGGCTGGCGGAAGACCTTGCTGAT
CGTCTCCCATGACCAGGGCTTCTTGGATGATGTCTGCACTGATATCATCCACCTCGATGCCCAGCGGCTCCACTACTATAGGGGCAATTA
CATGACCTTCAAAAAGATGTACCAGCAGAAGCAGAAAGAACTGCTGAAACAGTATGAGAAGCAAGAGAAAAAGCTGAAGGAGCTGAAGGC
AGGCGGGAAGTCCACCAAGCAGGCGGAAAAACAAACGAAGGAAGCCCTGACTCGGAAGCAGCAGAAATGCCGACGGAAAAACCAAGATGA
GGAATCCCAGGAGGCCCCTGAGCTCCTGAAGCGCCCTAAGGAGTACACTGTGCGCTTCACTTTTCCAGACCCCCCACCACTCAGCCCTCC
AGTGCTGGGTCTGCATGGTGTGACATTCGGCTACCAGGGACAGAAACCACTCTTTAAGAACTTGGATTTTGGCATCGACATGGATTCAAG
GATTTGCATTGTGGGCCCTAATGGTGTGGGGAAGAGTACGCTACTCCTGCTGCTGACTGGCAAGCTGACACCGTACATGGGCTGCATCGA
GGTTCTCCGCTCTATGCGCTCCCTGGACTTTAACACGCGCACGCAGGTGACCAGGGAAGCCATCAACCGGCTCCATGAGGCCGTGCCTGG
CGTCCGGGGATCCTGGAAGAAAAAGGCCCCCAACAAGGCCCTGGCGTCCGTCCTGGGCAAGAGCAACCTTCGCTTTGCCGGCATGAGCAT
CTCCATCCACATCTCCACTGATGGCCTCAGCCTCTCCGTGCCTGCCACGCGCCAGGTCATCGCCAACCACCACATGCCGTCCATCTCCTT
CGCGTCAGGCGGAGACACGGACATGACGGATTACGTGGCCTACGTCGCCAAGGACCCCATCAACCAGAGAGCCTGCCACATCCTGGAGTG
CTGTGAGGGCCTGGCACAGAGCATCATCAGCACCGTGGGCCAAGCTTTCGAGCTGCGCTTCAAGCAGTACCTGCACAGCCCGCCCAAGGT
GGCGCTGCCCCCAGAAAGGCTGGCAGGGCCGGAGGAGTCGGCCTGGGGGGACGAGGAGGACTCTTTGGAGCACAATTACTACAACAGCAT
CCCGGGGAAGGAGCCGCCGCTGGGCGGGCTAGTGGACTCCAGGCTGGCCCTGACACAGCCCTGCGCCCTCACGGCCCTCGACCAGGGCCC
ATCTCCTTCTCTAAGAGATGCCTGCAGCCTGCCATGGGACGTGGGGTCCACCGGTACAGCTCCACCGGGGGACGGCTACGTGCAGGCGGA
CGCCCGGGGCCCCCCGGACCACGAGGAGCACCTGTATGTCAACACCCAGGGTCTGGACGCCCCCGAGCCGGAGGACAGCCCCAAAAAGGA
TCTGTTTGACATGCGACCCTTTGAGGATGCCCTGAAGTTGCATGAGTGCTCAGTGGCGGCAGGCGTGACAGCAGCCCCTCTTCCCTTGGA
GGACCAGTGGCCCAGCCCCCCTACCCGCCGGGCCCCTGTGGCCCCCACGGAGGAACAGCTGCGTCAGGAGCCCTGGTACCACGGCCGGAT
GAGCCGCCGGGCGGCAGAGAGGATGCTTCGAGCTGACGGGGACTTCCTTGTGCGAGACAGCGTCACCAACCCCGGGCAGTATGTCCTCAC
CGGCATGCACGCCGGGCAGCCCAAGCACCTGCTGCTCGTGGACCCCGAGGGCGTGGTACGGACGAAGGACGTGCTGTTTGAGAGCATCAG
CCACCTGATCGACCACCACCTGCAGAACGGGCAGCCCATCGTGGCCGCCGAGAGTGAGCTGCACCTGCGTGGCGTGGTCTCACGGGAGCC
CTGAGCCAGGTGACCGTTCTCAGCCCTGGCTCCTGCCTGTTCTCAGCCCCGGCTCCTGCCTGTCATGGCCTTGGGGCTCTCAGCCCTCCT
CCTGGATCCTGGTCAGGCCGAACCACCGCTGCCTCTCCTTCCTCCGCATGAGCCTCTGGCATGGTCCTTCCTCCAGCTGGCCCCGGGCTG
GGCAGAGCCTCCTCCTGCCGGGGCCCCTGCCCACCCCCTCCTTTGCCTGGAGTGAGGGTGTTCATACCAAAGACGGAACCATTTCGCCTT
TAAAGAAAATATATCCAGAAGCAGCCGCTGCCTCGGAGCCCTGGCCCTTGGGTCCCCCTCTCGCCTGGCTGGTTCGGTCTAACGCCCCGG
AGAGTCAGGGCTCCCAGGACCCTGGGGAGGAGGCGGATTCCGGGCCTGGCTGGGCTTCCTCTTCCCACCTGAGGACTGGGTGCACAGTTG
TCTTTGAGGGGGGACGCTTAAGGTGCTTTGGGGTTCTCAGGCCAGGATACATGCTGGCGCTGAAGTGCAGGCAGCCTTGAGGTCACCTGG
GATCTCGGGGTAGCCAGGCTGCTCCAAGACAGTGGATATCGAGGCAGTCGTGAGGCCCCTACTCCACCTGGGAGCAGGGGAAGGACGTGG
TTGCCTGGCCTGGGCTGCGCCCAGCAGCTTCCCCCCAGTCCTGCCCTCCCAGCTGTCGACCCAGATGGGATGTTCGGATCGGTTTGTAAT

>In-frame_ABCF1_ENST00000376545_chr6_30554488_+_SHC2_ENST00000264554_chr19_440932_-_4038nt
GCGCCAGCTTGGAGAGCCAGCCCCATCGGGGTTCCCCGCCGCCGGAAGCGGAAATAGCACCGGGCGCCGCCACAGTAGCTGTAACTGCCA
CCGCGATGCCGAAGGCGCCCAAGCAGCAGCCGCCGGAGCCCGAGTGGATCGGGGACGGAGAGAGCACGAGCCCATCAGACAAAGTGGTGA
AGAAAGGGAAGAAGGACAAGAAGATCAAAAAAACGTTCTTTGAAGAGCTGGCAGTAGAAGATAAACAGGCTGGGGAAGAAGAGAAAGTGC
TCAAGGAGAAGGAGCAGCAGCAGCAGCAACAGCAACAGCAGCAAAAAAAAAAGCGAGATACCCGAAAAGGCAGGCGGAAGAAGGATGTGG
ATGATGATGGAGAAGAGAAAGAGCTCATGGAGCGTCTTAAGAAGCTCTCAGTGCCAACCAGTGATGAGGAGGATGAAGTACCCGCCCCAA
AACCCCGCGGAGGGAAGAAAACCAAGGGTGGTAATGTTTTTGCAGCCCTGATTCAGGATCAGAGTGAGGAAGAGGAGGAGGAAGAAAAAC
ATCCTCCTAAGCCTGCCAAGCCGGAGAAGAATCGGATCAATAAGGCCGTATCTGAGGAACAGCAGCCTGCACTCAAGGGCAAAAAGGGAA
AGGAAGAGAAGTCAAAAGGGAAGGCTAAGCCTCAAAATAAATTCGCTGCTCTGGACAATGAAGAGGAGGATAAAGAAGAAGAAATTATAA
AGGAAAAGGAGCCTCCCAAACAAGGGAAGGAGAAGGCCAAGAAGGCAGAGCAGATGGAGTATGAGCGCCAAGTGGCTTCATTAAAAGCAG
CCAATGCAGCTGAAAATGACTTCTCCGTGTCCCAGGCGGAGATGTCCTCCCGCCAAGCCATGTTAGAAAATGCATCTGACATCAAGCTGG
AGAAGTTCAGCATCTCCGCTCATGGCAAGGAGCTGTTCGTCAATGCAGACCTGTACATTGTAGCCGGCCGCCGCTACGGGCTGGTAGGAC
CCAATGGCAAGGGCAAGACCACACTCCTCAAGCACATTGCCAACCGAGCCCTGAGCATCCCTCCCAACATTGATGTGTTGCTGTGTGAGC
AGGAGGTGGTAGCAGATGAGACACCAGCAGTCCAGGCTGTTCTTCGAGCTGACACCAAGCGATTGAAGCTGCTGGAAGAGGAGCGGCGGC
TTCAGGGACAGCTGGAACAAGGGGATGACACAGCTGCTGAGAGGCTAGAGAAGGTGTATGAGGAATTGCGGGCCACTGGGGCGGCAGCTG
CAGAGGCCAAAGCACGGCGGATCCTGGCTGGCCTGGGCTTTGACCCTGAAATGCAGAATCGACCCACACAGAAGTTCTCAGGGGGCTGGC
GCATGCGTGTCTCCCTGGCCAGGGCACTGTTCATGGAGCCCACACTGCTGATGCTGGATGAGCCCACCAACCACCTGGACCTCAACGCTG
TCATCTGGCTTAATAACTACCTCCAGGGCTGGCGGAAGACCTTGCTGATCGTCTCCCATGACCAGGGCTTCTTGGATGATGTCTGCACTG
ATATCATCCACCTCGATGCCCAGCGGCTCCACTACTATAGGGGCAATTACATGACCTTCAAAAAGATGTACCAGCAGAAGCAGAAAGAAC
TGCTGAAACAGTATGAGAAGCAAGAGAAAAAGCTGAAGGAGCTGAAGGCAGGCGGGAAGTCCACCAAGCAGGCGGAAAAACAAACGAAGG
AAGCCCTGACTCGGAAGCAGCAGAAATGCCGACGGAAAAACCAAGATGAGGAATCCCAGGAGGCCCCTGAGCTCCTGAAGCGCCCTAAGG
AGTACACTGTGCGCTTCACTTTTCCAGACCCCCCACCACTCAGCCCTCCAGTGCTGGGTCTGCATGGTGTGACATTCGGCTACCAGGGAC
AGAAACCACTCTTTAAGAACTTGGATTTTGGCATCGACATGGATTCAAGGATTTGCATTGTGGGCCCTAATGGTGTGGGGAAGAGTACGC
TACTCCTGCTGCTGACTGGCAAGCTGACACCGTACATGGGCTGCATCGAGGTTCTCCGCTCTATGCGCTCCCTGGACTTTAACACGCGCA
CGCAGGTGACCAGGGAAGCCATCAACCGGCTCCATGAGGCCGTGCCTGGCGTCCGGGGATCCTGGAAGAAAAAGGCCCCCAACAAGGCCC
TGGCGTCCGTCCTGGGCAAGAGCAACCTTCGCTTTGCCGGCATGAGCATCTCCATCCACATCTCCACTGATGGCCTCAGCCTCTCCGTGC
CTGCCACGCGCCAGGTCATCGCCAACCACCACATGCCGTCCATCTCCTTCGCGTCAGGCGGAGACACGGACATGACGGATTACGTGGCCT
ACGTCGCCAAGGACCCCATCAACCAGAGAGCCTGCCACATCCTGGAGTGCTGTGAGGGCCTGGCACAGAGCATCATCAGCACCGTGGGCC
AAGCTTTCGAGCTGCGCTTCAAGCAGTACCTGCACAGCCCGCCCAAGGTGGCGCTGCCCCCAGAAAGGCTGGCAGGGCCGGAGGAGTCGG
CCTGGGGGGACGAGGAGGACTCTTTGGAGCACAATTACTACAACAGCATCCCGGGGAAGGAGCCGCCGCTGGGCGGGCTAGTGGACTCCA
GGCTGGCCCTGACACAGCCCTGCGCCCTCACGGCCCTCGACCAGGGCCCATCTCCTTCTCTAAGAGATGCCTGCAGCCTGCCATGGGACG
TGGGGTCCACCGGTACAGCTCCACCGGGGGACGGCTACGTGCAGGCGGACGCCCGGGGCCCCCCGGACCACGAGGAGCACCTGTATGTCA
ACACCCAGGGTCTGGACGCCCCCGAGCCGGAGGACAGCCCCAAAAAGGATCTGTTTGACATGCGACCCTTTGAGGATGCCCTGAAGTTGC
ATGAGTGCTCAGTGGCGGCAGGCGTGACAGCAGCCCCTCTTCCCTTGGAGGACCAGTGGCCCAGCCCCCCTACCCGCCGGGCCCCTGTGG
CCCCCACGGAGGAACAGCTGCGTCAGGAGCCCTGGTACCACGGCCGGATGAGCCGCCGGGCGGCAGAGAGGATGCTTCGAGCTGACGGGG
ACTTCCTTGTGCGAGACAGCGTCACCAACCCCGGGCAGTATGTCCTCACCGGCATGCACGCCGGGCAGCCCAAGCACCTGCTGCTCGTGG
ACCCCGAGGGCGTGGTACGGACGAAGGACGTGCTGTTTGAGAGCATCAGCCACCTGATCGACCACCACCTGCAGAACGGGCAGCCCATCG
TGGCCGCCGAGAGTGAGCTGCACCTGCGTGGCGTGGTCTCACGGGAGCCCTGAGCCAGGTGACCGTTCTCAGCCCTGGCTCCTGCCTGTT
CTCAGCCCCGGCTCCTGCCTGTCATGGCCTTGGGGCTCTCAGCCCTCCTCCTGGATCCTGGTCAGGCCGAACCACCGCTGCCTCTCCTTC
CTCCGCATGAGCCTCTGGCATGGTCCTTCCTCCAGCTGGCCCCGGGCTGGGCAGAGCCTCCTCCTGCCGGGGCCCCTGCCCACCCCCTCC
TTTGCCTGGAGTGAGGGTGTTCATACCAAAGACGGAACCATTTCGCCTTTAAAGAAAATATATCCAGAAGCAGCCGCTGCCTCGGAGCCC
TGGCCCTTGGGTCCCCCTCTCGCCTGGCTGGTTCGGTCTAACGCCCCGGAGAGTCAGGGCTCCCAGGACCCTGGGGAGGAGGCGGATTCC
GGGCCTGGCTGGGCTTCCTCTTCCCACCTGAGGACTGGGTGCACAGTTGTCTTTGAGGGGGGACGCTTAAGGTGCTTTGGGGTTCTCAGG
CCAGGATACATGCTGGCGCTGAAGTGCAGGCAGCCTTGAGGTCACCTGGGATCTCGGGGTAGCCAGGCTGCTCCAAGACAGTGGATATCG
AGGCAGTCGTGAGGCCCCTACTCCACCTGGGAGCAGGGGAAGGACGTGGTTGCCTGGCCTGGGCTGCGCCCAGCAGCTTCCCCCCAGTCC


Top

FusionGenePPI for ABCF1_SHC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ABCF1EIF6, HDGF, SIRT7, CUL2, COPS5, GRK5, APP, FMNL1, FN1, MMS19, C14orf166, RTCB, NELFB, YBX3, DDX1, DIMT1, EDC4, EIF2B2, EIF2B3, FKBP3, FRYL, RFC4, DHX9, DYNC1I2, HNRNPA0, HNRNPA2B1, HNRNPM, HNRNPU, IGF2BP3, ILF2, MAP2, MRE11A, NMT1, PSMC5, PSMC6, PSMD13, PSMD7, PSMD8, PTBP1, RPL27A, TBL1XR1, OBSL1, CCDC8, EED, RNF2, ABCE1, SPAG6, SUB1, HMGN1P30, NTRK1, XPO1, EMC2, NOP56, CNOT1, TIGD6, MCM2, UBXN7, OTUB1, POU5F1, RPGRIP1L, TRIM25SHC2KDR, ARHGAP32, FLT1, EGFR, ERBB2, ERRFI1, GRB2, SHC1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for ABCF1_SHC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for ABCF1_SHC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCF1C0020517Hypersensitivity1CTD_human
HgeneABCF1C0032285Pneumonia1CTD_human