|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 1856 |
FusionGeneSummary for ANKRD42_PICALM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD42_PICALM | Fusion gene ID: 1856 | Hgene | Tgene | Gene symbol | ANKRD42 | PICALM | Gene ID | 338699 | 8301 |
| Gene name | ankyrin repeat domain 42 | phosphatidylinositol binding clathrin assembly protein | |
| Synonyms | PPP1R79|SARP | CALM|CLTH|LAP | |
| Cytomap | 11q14.1 | 11q14.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 42protein phosphatase 1, regulatory subunit 79several ankyrin repeat protein | phosphatidylinositol-binding clathrin assembly proteinclathrin assembly lymphoid myeloid leukemia protein | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8N9B4 | Q13492 | |
| Ensembl transtripts involved in fusion gene | ENST00000528190, ENST00000393389, ENST00000528722, ENST00000260047, ENST00000526731, ENST00000531895, ENST00000393392, ENST00000533342, | ENST00000532317, ENST00000526033, ENST00000393346, ENST00000528398, ENST00000356360, ENST00000528411, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 7 X 12 X 4=336 |
| # samples | 2 | 14 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(14/336*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD42 [Title/Abstract] AND PICALM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PICALM | GO:0006898 | receptor-mediated endocytosis | 10436022 |
| Tgene | PICALM | GO:0032880 | regulation of protein localization | 10436022 |
| Tgene | PICALM | GO:0045893 | positive regulation of transcription, DNA-templated | 11425879 |
| Tgene | PICALM | GO:0048261 | negative regulation of receptor-mediated endocytosis | 10436022 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | HNSC | TCGA-CV-7422-01A | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000528190 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000528190 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000528190 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000528190 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000528190 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-intron | ENST00000528190 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000393389 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000393389 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000393389 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000393389 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000393389 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5CDS-intron | ENST00000393389 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-3CDS | ENST00000528722 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-3CDS | ENST00000528722 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-3CDS | ENST00000528722 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-3CDS | ENST00000528722 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-3CDS | ENST00000528722 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5UTR-intron | ENST00000528722 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000260047 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000260047 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000260047 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000260047 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000260047 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5CDS-intron | ENST00000260047 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000526731 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000526731 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000526731 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000526731 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000526731 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5CDS-intron | ENST00000526731 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000531895 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000531895 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000531895 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000531895 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000531895 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5CDS-intron | ENST00000531895 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000393392 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000393392 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000393392 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000393392 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-3CDS | ENST00000393392 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| intron-intron | ENST00000393392 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000533342 | ENST00000532317 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000533342 | ENST00000526033 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000533342 | ENST00000393346 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| Frame-shift | ENST00000533342 | ENST00000528398 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| In-frame | ENST00000533342 | ENST00000356360 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
| 5CDS-intron | ENST00000533342 | ENST00000528411 | ANKRD42 | chr11 | 82909684 | + | PICALM | chr11 | 85670103 | - |
Top |
FusionProtFeatures for ANKRD42_PICALM |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD42 | PICALM |
| Assembly protein recruiting clathrin and adapter proteincomplex 2 (AP2) to cell membranes at sites of coated-pit formationand clathrin-vesicle assembly. May be required to determine theamount of membrane to be recycled, possibly by regulating the sizeof the clathrin cage. Involved in AP2-dependent clathrin-mediatedendocytosis at the neuromuscular junction.{ECO:0000269|PubMed:10436022}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for ANKRD42_PICALM |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_79aa >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_79aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_237nt ATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATA CATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_2531nt GCCTCTCCAGCCAAGTGGCTGGAGTCGGGAGGCTGGAAAGAGACTCCGAGAAAGTACCAGCGGAAGGCGGCCGCCGCTACGGCGATTCGC AGGGAGTAGCAGACGAAGACGGTGGCCGCCGCACTAGCCACCACGTGTGGAGGATAAACGGTCTACACGGCCATTCCGGCGCCGAGTCTA GGGAAAGAGTTAGCGACGACGGGGAAAGAAAATGTGAAGAGAGCGACCGCCGCTCCAGGGTCGCTGCAGGAAGCCTAAGTGCAGACGCCG GCTTCTCCCGCAGTGACTTGAGAAGGGTCAGTGAAAACCTCGGCCACTGCCGCAGCGTCTCTAGGGAGAGAGTTAGGGGAGATAGTGGCC ACAGTCACAGCTGCTCTTGGGAGAGAGTTAGGGGAGACAGCACCTTCTGCAGCAGCGACGTGAATTTTAGTGAAGTTGGAGGCCACCAAA CTACCGACTCCAGGGGAACAGCCAGAGAAGACCGAGGCCTCCGCCTCAGTGGTCCTTGGGAGGGAGTCAGTGACATTCGGGACCCGCGAA CTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTCAGTGGCTCCTGGGAGGGAGGGAGTGTCGAAGGCGGCCACAGCG TTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACC GCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTC CTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACT CAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCT GTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAG CCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAAC TTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTA AATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACG TATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCC TGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGA ACTGTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCC TCACAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTG TATTTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGA TTTTTATCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTG AATCTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTG CCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGC ATGTCATTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAA ACTCTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTT TAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTG TGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCAT TCTTGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGCAAAATGGGTGGATTTTCAAATAAAATGCAG >In-frame_ANKRD42_ENST00000393389_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_1228nt GCCTCTCCAGCCAAGTGGCTGGAGTCGGGAGGCTGGAAAGAGACTCCGAGAAAGTACCAGCGGAAGGCGGCCGCCGCTACGGCGATTCGC AGGGAGTAGCAGACGAAGACGGTGGCCGCCGCACTAGCCACCACGTGTGGAGGATAAACGGTCTACACGGCCATTCCGGCGCCGAGTCTA GGGAAAGAGTTAGCGACGACGGGGAAAGAAAATGTGAAGAGAGCGACCGCCGCTCCAGGGTCGCTGCAGGAAGCCTAAGTGCAGACGCCG GCTTCTCCCGCAGTGACTTGAGAAGGGTCAGTGAAAACCTCGGCCACTGCCGCAGCGTCTCTAGGGAGAGAGTTAGGGGAGATAGTGGCC ACAGTCACAGCTGCTCTTGGGAGAGAGTTAGGGGAGACAGCACCTTCTGCAGCAGCGACGTGAATTTTAGTGAAGTTGGAGGCCACCAAA CTACCGACTCCAGGGGAACAGCCAGAGAAGACCGAGGCCTCCGCCTCAGTGGTCCTTGGGAGGGAGTCAGTGACATTCGGGACCCGCGAA CTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTCAGTGGCTCCTGGGAGGGAGGGAGTGTCGAAGGCGGCCACAGCG TTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACC GCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTC CTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACT CAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCT GTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAG CCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAAC >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_2394nt TGGAGGATAAACGGTCTACACGGCCATTCCGGCGCCGAGTCTAGGGAAAGAGTTAGCGACGACGGGGAAAGAAAATGTGAAGAGAGCGAC CGCCGCTCCAGGGTCGCTGCAGGAAGCCTAAGTGCAGACGCCGGCTTCTCCCGCAGTGACTTGAGAAGGGTCAGTGAAAACCTCGGCCAC TGCCGCAGCGTCTCTAGGGAGAGAGTTAGGGGAGATAGTGGCCACAGTCACAGCTGCTCTTGGGAGAGAGTTAGGGGAGACAGCACCTTC TGCAGCAGCGACGTGAATTTTAGTGAAGTTGGAGGCCACCAAACTACCGACTCCAGGGGAACAGCCAGAGAAGACCGAGGCCTCCGCCTC AGTGGTCCTTGGGAGGGAGTCAGTGACATTCGGGACCCGCGAACTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTC AGTGGCTCCTGGGAGGGAGGGAGTGTCGAAGGCGGCCACAGCGTTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCC AGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGC TGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGG GTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCC AATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGA GCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACAT TGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCA GCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAG TGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAA GATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGG AAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAA ATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAA AAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAG ACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTG ACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTAT AAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCA GCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGT GAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTG AACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGT TTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGA CAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAA >In-frame_ANKRD42_ENST00000260047_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_1091nt TGGAGGATAAACGGTCTACACGGCCATTCCGGCGCCGAGTCTAGGGAAAGAGTTAGCGACGACGGGGAAAGAAAATGTGAAGAGAGCGAC CGCCGCTCCAGGGTCGCTGCAGGAAGCCTAAGTGCAGACGCCGGCTTCTCCCGCAGTGACTTGAGAAGGGTCAGTGAAAACCTCGGCCAC TGCCGCAGCGTCTCTAGGGAGAGAGTTAGGGGAGATAGTGGCCACAGTCACAGCTGCTCTTGGGAGAGAGTTAGGGGAGACAGCACCTTC TGCAGCAGCGACGTGAATTTTAGTGAAGTTGGAGGCCACCAAACTACCGACTCCAGGGGAACAGCCAGAGAAGACCGAGGCCTCCGCCTC AGTGGTCCTTGGGAGGGAGTCAGTGACATTCGGGACCCGCGAACTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTC AGTGGCTCCTGGGAGGGAGGGAGTGTCGAAGGCGGCCACAGCGTTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCC AGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGC TGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGG GTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCC AATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGA GCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACAT TGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCA >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_2021nt AGGGAGTCAGTGACATTCGGGACCCGCGAACTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTCAGTGGCTCCTGGG AGGGAGGGAGTGTCGAAGGCGGCCACAGCGTTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCCAGCGACTCCTCTG GTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGCTGCAGCTTCTGGG AGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGGGTGAGAGCAAGTG AAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCT CCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAA AGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATT CTGGAAGTTTGGAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTAC TTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGA AGGAAATTGGGACTAGTTTATAGGAGAACGTATCAATACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTT GGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATT TGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTA ATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAAATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTC AGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACCTCCTTATGAA AATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTGACATACAGAGCAC TAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATC CTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTGCATT GGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTT CACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTG GCTCGTGCCATGTTATGATCATATACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAG AATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAG GAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGC >In-frame_ANKRD42_ENST00000526731_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_718nt AGGGAGTCAGTGACATTCGGGACCCGCGAACTAGTGACTTCGGGGATAGAGTCAGTGACGATCGCAGTCGCCGCTTCAGTGGCTCCTGGG AGGGAGGGAGTGTCGAAGGCGGCCACAGCGTTGGTAGTTCTTGGGAGGAAGTAAGTGGAGACCGCGGCTACGCAGCCAGCGACTCCTCTG GTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGTGAAGACGAAGGTTTCCGCTGCAGCTTCTGGG AGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGCCGCTGCAGTGGCTCGTGGGTGAGAGCAAGTG AAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCT CCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAA AGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATT >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_1872nt GACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGT GAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGC CGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGC GCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGC ATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCAT AAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAA AAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTCTTAAACTCTCTTCTTCCATTAGA ATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTATCAATACAGTTTATAAAGCCAAGAATT GCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAATACCCATAATCAGTAACCTATCA AGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTGTCCTTTACTGTATTTCAACAGGA CTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAAATACAGAAACAATAACTGAAATT AACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTATTTATGATTATCAATTTTACATA ACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTATCCACAAGAATGAATCTGATTCA GAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTCTTAAGAATTCTCGGCCTCTGTGG GATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGGAACAGTTCACTGACTAGGAAAAG CACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCATTATTTTCCATTTGACATTAGGG CCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTAGAAGGTGTTACAAGGGGGAGGGA AGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAAATAAGGGGAAATAGTATCTTTAAAGT TAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAATACATCTTTAACATTTGGGTGGA GAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGTTGCATTGTCTCTGCAGATTCTAT >In-frame_ANKRD42_ENST00000531895_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_569nt GACCGCGGCTACGCAGCCAGCGACTCCTCTGGTGTGAGCGGCAGTGAAGACGCCAGCTACCGCTTCAGTGGCTTTTGGGAGAGAGAAAGT GAAGACGAAGGTTTCCGCTGCAGCTTCTGGGAGAGAGCAAGAGAGGACCTTGGGCCCCGTCCTAGTGACGACGGAGAAGAGGGCCGCTGC CGCTGCAGTGGCTCGTGGGTGAGAGCAAGTGAAGACCGCCGCAGCATCAGGGGCCTGGACTCAACTCCTCCCCAGAGTCGGAGGTGTTGC GCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCAGGAAGAAGGTGCATTTTGGCAGC ATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCATTAATGAACTTGATGTTCTCCAT AAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATGGAAGAAAATGGAATTACTCCAAA >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000532317_chr11_85670103_-_1625nt CTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCA GGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCA TTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATG GAAGAAAATGGAATTACTCCAAAAAGACAAGTGCTCAAGCAGCAAAATCCTTACTTCCAGCAAAATCCAAACTGCTGTCTCTTAAATCTC TTAAACTCTCTTCTTCCATTAGAATGCTACAAGTAACTCAGTGAAGGCCCATGAAGGAAATTGGGACTAGTTTATAGGAGAACGTATCAA TACAGTTTATAAAGCCAAGAATTGCTATGATTTAAGACTAAGATCTGTCTTTTTGGTGACTAACCCTTCAATTCTTTCAACTCCTGTTAA TACCCATAATCAGTAACCTATCAAGAAAAGCCCTTATTTGGAAAGTGTGAAATTTGTATTTGGAAAAGCTGCCTGGAGAGAAGAACTGTG TCCTTTACTGTATTTCAACAGGACTCTTTTGGGGGATCAAAATTAAAATTCCTAATTATGCATTATCTTTCTTTTCTCCAGTCCTCACAA ATACAGAAACAATAACTGAAATTAACTTTTCTTTTTTTAAAAAAAATTATATTCAGTTTGCAGTAGACATTCCTTAAGTATTTGTATTTA TTTATGATTATCAATTTTACATAACATTAATATTGTATCAGACCTCCTTATGAAAATGAGTATGGATGTGCACAGTATGTTTGATTTTTA TCCACAAGAATGAATCTGATTCAGAATGCTTTTCTCAGCTGACATACAGAGCACTAAATATTTTAAGGCAAGTCCATAGGTCTGAATCTC TTAAGAATTCTCGGCCTCTGTGGGATTTAGGGAAGCATTATAAATGCATTAATCCTTATAGTCAATTCTGTGCCTAGGATTTTGCCAGGG AACAGTTCACTGACTAGGAAAAGCACTACATTTTAAATTCAGCATTAGTGCATTGGGAAGGATCTTTACTGCTTTGTGCTTGGCATGTCA TTATTTTCCATTTGACATTAGGGCCTTTCCAAAATGAATGTGAGGAATTGCTTTCACTTCAAGACTTTCCTTCTTTTCACTAAAACTCTA GAAGGTGTTACAAGGGGGAGGGAAGGGGGGCAAAGTCCTTGAACATTTTCTTTGGCTCGTGCCATGTTATGATCATATACCTTTTAAATA AGGGGAAATAGTATCTTTAAAGTTAATGTCTAGCCAAGAGTTTAGTAAACGAAGAATTAAACTGCACTGTTGATCGGTGCTTTGTGTAAA TACATCTTTAACATTTGGGTGGAGAGGGGCCTTAAGAAGGACAGTTCATTGTAGGAAAGCAATTCTGTACATGAGTTTAAGCATTCTTGT TGCATTGTCTCTGCAGATTCTATTTTTGTTTACAATATTAAAATGTATGTTAGCAAAATGGGTGGATTTTCAAATAAAATGCAGCTTCCA >In-frame_ANKRD42_ENST00000533342_chr11_82909684_+_PICALM_ENST00000356360_chr11_85670103_-_322nt CTCCCCAGAGTCGGAGGTGTTGCGCCATGCCCGGGGTGGCCAATTCAGGCCCCTCCACTTCCTCTAGGGAGACTGCAAACCCCTGTTCCA GGAAGAAGGTGCATTTTGGCAGCATACATGATGCAGTACGAGCTGGAGATGTAAAGCAGCTTTCAGAAATAGTGGTACGTGGAGCCAGCA TTAATGAACTTGATGTTCTCCATAAGTTTACCCCTTTACATTGGGCAGCACATTCTGGAAGTTTGGAGATACAGTTTATGTAACTTGATG |
Top |
FusionGenePPI for ANKRD42_PICALM |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ANKRD42 | PPP1CC | PICALM | PLCG1, CLTC, ITSN1, AP2A1, HIP1R, LAMTOR3, EEF1A1, SEC24D, DNM2, EGFR, FLOT1, SEC24C, ATP6V1E1, ILF3, HNRNPDL, SH3GLB2, ABCC2, ATP6V1F, CD55, SIRT1, FN1, VCAM1, ITGA4, PELI2, KLHL20, SLC25A41, ITLN1, ATF6B, SLC25A32, SOX2, FAM64A, CYP1A1, HNRNPA1, UNK, NTRK1, C14orf166, CARS, CPPED1, HNRNPD, ILVBL, ITGB1, LPP, PAPOLA, DDX1, EWSR1, FERMT2, FUS, ILK, NPLOC4, PFKM, PTPRF, VCL, PXN, STXBP1, TRIM25, UNC13D, XPO1, AP2B1, AP2M1, CLTA, CLTB, DAB2, EPS15, GAK, MYO6, PIK3C2A, SEC13, CLTCL1, CAPZA2, DBN1, MYH9, LIMA1, GTSE1, ANLN, MYO19, MYO18A, CLINT1, SEC16A, TNRC6A, BMP2K, MICAL3, DENND1A, WNK1, PRRC2B, STON2, FCHO2, MCM2, SNW1, CDC5L, SMURF1, CDH1, STAMBPL1, RALBP1, SNRNP27, DLST |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for ANKRD42_PICALM |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ANKRD42_PICALM |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PICALM | C0002395 | Alzheimer's Disease | 2 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|