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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 18468

FusionGeneSummary for KDM4C_DMRT3

check button Fusion gene summary
Fusion gene informationFusion gene name: KDM4C_DMRT3
Fusion gene ID: 18468
HgeneTgene
Gene symbol

KDM4C

DMRT3

Gene ID

23081

58524

Gene namelysine demethylase 4Cdoublesex and mab-3 related transcription factor 3
SynonymsGASC1|JHDM3C|JMJD2C|TDRD14CDMRTA3
Cytomap

9p24.1

9p24.3

Type of geneprotein-codingprotein-coding
Descriptionlysine-specific demethylase 4CJmjC domain-containing histone demethylation protein 3Cgene amplified in squamous cell carcinoma 1 proteinjumonji domain-containing protein 2Clysine (K)-specific demethylase 4Ctudor domain containing 14Cdoublesex- and mab-3-related transcription factor 3DMRT-like family A3testis-specific protein
Modification date2018052320180523
UniProtAcc

Q9H3R0

Q9NQL9

Ensembl transtripts involved in fusion geneENST00000535193, ENST00000543771, 
ENST00000381306, ENST00000381309, 
ENST00000442236, ENST00000489243, 
ENST00000536108, ENST00000428870, 
ENST00000401787, 
ENST00000190165, 
Fusion gene scores* DoF score11 X 8 X 10=8801 X 1 X 1=1
# samples 121
** MAII scorelog2(12/880*10)=-2.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: KDM4C [Title/Abstract] AND DMRT3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKDM4C

GO:0006357

regulation of transcription by RNA polymerase II

17277772

HgeneKDM4C

GO:0033169

histone H3-K9 demethylation

18066052|21914792

HgeneKDM4C

GO:0070544

histone H3-K36 demethylation

21914792


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVCESCTCGA-EK-A2IR-01AKDM4Cchr9

6814745

+DMRT3chr9

990041

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000535193ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
In-frameENST00000543771ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
In-frameENST00000381306ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
In-frameENST00000381309ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
5UTR-3CDSENST00000442236ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
3UTR-3CDSENST00000489243ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
intron-3CDSENST00000536108ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
intron-3CDSENST00000428870ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+
Frame-shitENST00000401787ENST00000190165KDM4Cchr9

6814745

+DMRT3chr9

990041

+

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FusionProtFeatures for KDM4C_DMRT3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KDM4C

Q9H3R0

DMRT3

Q9NQL9

Probable transcription factor that plays a role inconfiguring the spinal circuits controlling stride in vertebrates.Involved in neuronal specification within specific subdivision ofspinal cord neurons and in the development of a coordinatedlocomotor network controlling limb movements. May regulatetranscription during sexual development (By similarity).{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+42116_581451048DomainJmjN
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+42216_581451057DomainJmjN
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+41816_58167836DomainJmjN
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+41816_58145814DomainJmjN

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421144_3101451048DomainJmjC
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421877_9341451048DomainNote=Tudor 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421935_9911451048DomainNote=Tudor 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422144_3101451057DomainJmjC
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422877_9341451057DomainNote=Tudor 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422935_9911451057DomainNote=Tudor 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418144_310167836DomainJmjC
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418877_934167836DomainNote=Tudor 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418935_991167836DomainNote=Tudor 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418144_310145814DomainJmjC
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418877_934145814DomainNote=Tudor 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418935_991145814DomainNote=Tudor 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421689_7471451048Zinc fingerNote=PHD-type 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421752_7851451048Zinc fingerC2HC pre-PHD-type
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381306+421808_8651451048Zinc fingerPHD-type 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422689_7471451057Zinc fingerNote=PHD-type 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422752_7851451057Zinc fingerC2HC pre-PHD-type
HgeneKDM4Cchr9:6814745chr9:990041ENST00000381309+422808_8651451057Zinc fingerPHD-type 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418689_747167836Zinc fingerNote=PHD-type 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418752_785167836Zinc fingerC2HC pre-PHD-type
HgeneKDM4Cchr9:6814745chr9:990041ENST00000535193+418808_865167836Zinc fingerPHD-type 2
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418689_747145814Zinc fingerNote=PHD-type 1
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418752_785145814Zinc fingerC2HC pre-PHD-type
HgeneKDM4Cchr9:6814745chr9:990041ENST00000543771+418808_865145814Zinc fingerPHD-type 2
TgeneDMRT3chr9:6814745chr9:990041ENST00000190165+0229_76151473DNA bindingDM


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FusionGeneSequence for KDM4C_DMRT3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_KDM4C_ENST00000535193_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_488aa
MKHTGLPWKRTEEAAADTALTIMEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCTDDIDNLL
IPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKTCTPRYLDYEDLERKYWKNLTFVAPITGADINGSITDEI_LKNDLETASRQ
TIQRSSVTKTLTRGVPQMWQRVRAASPLRALR_CPWRKGDTLSRKTEATPRAALTAPSVTRSRITS_LRAPRGLFLCPSA_KPTDRRLKC
_KRTSPTRSQRCLSSSSRAVAGTW_APWKSFCPADPQSREQSELPQNLRV_RCPPMGTSLNTP_APTPSRLPNGLWDQPFESQTR_GFLP
TLATLSPVPWLGLCSPLSPSHPGTR_C_GILWREASRAPFCPMMSPCGTP_RCSSSIS_GPSMSVLSPVTLPASSEARPSFLPAPRKTLG

>In-frame_KDM4C_ENST00000543771_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_466aa
MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCTDDIDNLLIPAPIQQMVTGQSGLFTQYNIQ
KKAMTVKEFRQLANSGKTCTPRYLDYEDLERKYWKNLTFVAPITGADINGSITDEI_LKNDLETASRQTIQRSSVTKTLTRGVPQMWQRV
RAASPLRALR_CPWRKGDTLSRKTEATPRAALTAPSVTRSRITS_LRAPRGLFLCPSA_KPTDRRLKC_KRTSPTRSQRCLSSSSRAVAG
TW_APWKSFCPADPQSREQSELPQNLRV_RCPPMGTSLNTP_APTPSRLPNGLWDQPFESQTR_GFLPTLATLSPVPWLGLCSPLSPSHP
GTR_C_GILWREASRAPFCPMMSPCGTP_RCSSSIS_GPSMSVLSPVTLPASSEARPSFLPAPRKTLGFPSLMMGVHLCQSSPFTPRTTM

>In-frame_KDM4C_ENST00000381306_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_466aa
MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCTDDIDNLLIPAPIQQMVTGQSGLFTQYNIQ
KKAMTVKEFRQLANSGKTCTPRYLDYEDLERKYWKNLTFVAPITGADINGSITDEI_LKNDLETASRQTIQRSSVTKTLTRGVPQMWQRV
RAASPLRALR_CPWRKGDTLSRKTEATPRAALTAPSVTRSRITS_LRAPRGLFLCPSA_KPTDRRLKC_KRTSPTRSQRCLSSSSRAVAG
TW_APWKSFCPADPQSREQSELPQNLRV_RCPPMGTSLNTP_APTPSRLPNGLWDQPFESQTR_GFLPTLATLSPVPWLGLCSPLSPSHP
GTR_C_GILWREASRAPFCPMMSPCGTP_RCSSSIS_GPSMSVLSPVTLPASSEARPSFLPAPRKTLGFPSLMMGVHLCQSSPFTPRTTM

>In-frame_KDM4C_ENST00000381309_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_466aa
MEVAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCTDDIDNLLIPAPIQQMVTGQSGLFTQYNIQ
KKAMTVKEFRQLANSGKTCTPRYLDYEDLERKYWKNLTFVAPITGADINGSITDEI_LKNDLETASRQTIQRSSVTKTLTRGVPQMWQRV
RAASPLRALR_CPWRKGDTLSRKTEATPRAALTAPSVTRSRITS_LRAPRGLFLCPSA_KPTDRRLKC_KRTSPTRSQRCLSSSSRAVAG
TW_APWKSFCPADPQSREQSELPQNLRV_RCPPMGTSLNTP_APTPSRLPNGLWDQPFESQTR_GFLPTLATLSPVPWLGLCSPLSPSHP
GTR_C_GILWREASRAPFCPMMSPCGTP_RCSSSIS_GPSMSVLSPVTLPASSEARPSFLPAPRKTLGFPSLMMGVHLCQSSPFTPRTTM


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_KDM4C_ENST00000535193_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_1466nt
ATGAAGCACTATGGGCTGCCCTGGAAGAGGACTGAAGAAGCAGCTGCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGT
CCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCT
AAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTC
ATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAG
TTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACT
TTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCATATATGATGAGATTTGACTGAAGAACGACTTGGAGACGGCAAGTCGGCAG
ACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTAAGGGCTGCTTCACCCCTGAGAGCC
CTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCCGCCCTGACAGCCCCAAGTGTCACG
CGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAGCCAACAGACCGCCGCTTGAAGTGT
TAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGGACCTGGTGAGCGCCGTGGAAGTCC
TTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGTTGCCCTCCAATGGGCACATCTTTG
AACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCCCAGACACGTTGAGGTTTTCTGCCG
ACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCCGGTACCCGCTGATGCTGAGGAATA
CTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGCTGCAGCAGCAGTATCAGCTGAGGT
CCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTGCCCGCGCCACGGAAGACCCTCGGA
TTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATGACGAGAGGTCTGACTCCTCAGACT

>In-frame_KDM4C_ENST00000543771_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_1400nt
ATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAAC
AAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGC
TATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAG
AAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAG
CGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCATATATGATGAGATTTGACTGAAGAAC
GACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTA
AGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCC
GCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAG
CCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGG
ACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGT
TGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCC
CAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCC
GGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGC
TGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTG
CCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATG

>In-frame_KDM4C_ENST00000381306_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_1400nt
ATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAAC
AAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGC
TATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAG
AAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAG
CGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCATATATGATGAGATTTGACTGAAGAAC
GACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTA
AGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCC
GCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAG
CCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGG
ACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGT
TGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCC
CAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCC
GGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGC
TGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTG
CCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATG

>In-frame_KDM4C_ENST00000381309_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_1400nt
ATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAAC
AAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGC
TATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAG
AAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAG
CGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCATATATGATGAGATTTGACTGAAGAAC
GACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTA
AGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCC
GCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAG
CCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGG
ACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGT
TGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCC
CAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCC
GGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGC
TGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTG
CCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATG


* Fusion transcript sequences (Full-length transcript).
>In-frame_KDM4C_ENST00000535193_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_2278nt
ATGGCTGACATGATGGTCTGTGACCTGAAAGTTGTTGAATAGTTGGAGTGTTCTGCATTCATGTGGAAGAGGCTAAAGGATGTTTGATGA
AGCACTATGGGCTGCCCTGGAAGAGGACTGAAGAAGCAGCTGCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTC
TGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAG
GAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTC
CAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAGTTCA
GGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTG
TGGCACCTATCTATGGTGCAGATATTAATGGGAGCATATATGATGAGATTTGACTGAAGAACGACTTGGAGACGGCAAGTCGGCAGACAA
TACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTAAGGGCTGCTTCACCCCTGAGAGCCCTGA
GATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCCGCCCTGACAGCCCCAAGTGTCACGCGGA
GCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAGCCAACAGACCGCCGCTTGAAGTGTTAAA
AAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGGACCTGGTGAGCGCCGTGGAAGTCCTTCT
GTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGTTGCCCTCCAATGGGCACATCTTTGAACA
CACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCCCAGACACGTTGAGGTTTTCTGCCGACTC
TAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCCGGTACCCGCTGATGCTGAGGAATACTTT
GGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGCTGCAGCAGCAGTATCAGCTGAGGTCCCA
GTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTGCCCGCGCCACGGAAGACCCTCGGATTTC
CATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATGACGAGAGGTCTGACTCCTCAGACTCTAG
AACACTCAACACATCATCTTAAAGTGGTGCTGGATGGGTGGTGGCCAGGTGACATTTTCTGTGCGTTTTGACCCTGAGGCATCTGAGGAG
AGGCCACATCTTGTGTATGCCCTTTCCTTCTGTTTGACAAAGTGACTGTGCTTGATTCTATACATTAGCAATAAAAACATAACTTATTTA
ACTTCTTGCACTTCACTGGAAAATGCCAAATAGCTCTGTTCTGTGGCTTTAGTGCTGAATGTTTATTGTAAAAGAGAGTCTAATGTTAAG
AATAGTCTTGGGAAGGCTGGGTCCGTGGAAGATTTATTTGGGGATGTAAAGCTGAAGGTCAGCCTTGCACCTAAACCCAACCTGGAATGT
TAAATGAAATAATATACTTGAATGCAATTTTGTAAAAGTGGATTCCTCAGGATATGTGAAACCTAAAGGAAGTGGTTCTGTTGCAAATGG
ACTATAAACAGGGACATTATATTCTTACACTAAAAATCCTTGCATTTTAAAGAGAGATGCACTTAAGAATAGAGTGAACTGCTCATATGC
TTATTTAAGCTTGGACAGTTTTCAGAGACAAACCCCATTAAGAATTACTCTTTTCACATGGCTGAATCGAAACATGTGTAATGTCAATGT
AAAACCAATCACAGCTGTGAACTGCATGAAATGTATTGTGAAACGAACACAAGATTAAGCTTTGTCAGGTTAATGTAGCATGTTAAGGAC

>In-frame_KDM4C_ENST00000543771_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_2706nt
GCCATAGGTGCGCGTCGGCGCCCAGGAGGACGTGTGGCGCGTGGACTACATCAGGTCCAGCCCTGCGGGACCCCAGCCAGCGCTTCCGGG
CAAGGTTCTGTGCACCTGTTTTCTCCTTCTACGCGAGTATCTTTCCCCTCCGGAAAGAATGGGATATGCCTGTGTCCAAAGGACAAGAAG
ATGCGCGCCAGCAAGCCTAAGTTAACCACAGCGCGGAAGTTGAGCCCAAAGCAAGAGCGTGCCGGGCACCTTTAAGCTGTTTGTAAGCCC
ACGTGACTCACCAAGTGCGGGCCCCAGCGGTCACGTGACGGCGCGCGCGCCCTCGCGCAGGGAGAGCCGGCGGTGCGCGCGCCTTCGCCG
CTGCCTCCCACCCACCCCCTCGACGGGAGGGTGAGGCGCGGCGCAGTGATCGGGCGGCCGGGGTCCTGTGCGCGTGCGCAGCGAACAGCT
GTCACCTAGTGCGGAACAAGTCTCCCAAATTTCCCAAATCTCCCTGGGCCGGAGGCCACTGTCTTCTCTTCCTCCTCCACCGAGTCGTGC
TCTCGCCCCAACCCGCGCGCCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAAT
GACCTTCAGACCCTCCATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGC
AAAGGTGATTCCTCCTAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGT
CACAGGGCAGTCAGGACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAA
ATATTGTACTCCAAGATACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGA
TATTAATGGGAGCATATATGATGAGATTTGACTGAAGAACGACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAA
GACACTGACCAGAGGAGTTCCCCAGATGTGGCAAAGAGTAAGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGG
GGATACGCTGTCCAGAAAAACGGAGGCAACCCCGAGAGCCGCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAG
GGCCCCTCGGGGACTGTTTCTCTGCCCTTCAGCTTGAAAGCCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAG
CCAACGGTGCTTGAGCTCATCCTCAAGGGCTGTGGCGGGGACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACG
GGAGCAGAGCGAACTTCCGCAGAACCTGAGAGTCTAGCGTTGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATC
TCGTCTTCCAAATGGTCTGTGGGATCAGCCTTTCGAGTCCCAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCC
TTGGCTGGGCCTCTGCAGCCCCCTTTCCCCCAGCCACCCCGGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCC
TTTTTGCCCAATGATGTCACCCTGTGGAACACCATGACGCTGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGT
AACTCTACCAGCGTCTTCAGAAGCTCGCCCGTCCTTCCTGCCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCA
TTTGTGTCAAAGCAGTCCATTTACACCGAGGACGACTATGACGAGAGGTCTGACTCCTCAGACTCTAGAACACTCAACACATCATCTTAA
AGTGGTGCTGGATGGGTGGTGGCCAGGTGACATTTTCTGTGCGTTTTGACCCTGAGGCATCTGAGGAGAGGCCACATCTTGTGTATGCCC
TTTCCTTCTGTTTGACAAAGTGACTGTGCTTGATTCTATACATTAGCAATAAAAACATAACTTATTTAACTTCTTGCACTTCACTGGAAA
ATGCCAAATAGCTCTGTTCTGTGGCTTTAGTGCTGAATGTTTATTGTAAAAGAGAGTCTAATGTTAAGAATAGTCTTGGGAAGGCTGGGT
CCGTGGAAGATTTATTTGGGGATGTAAAGCTGAAGGTCAGCCTTGCACCTAAACCCAACCTGGAATGTTAAATGAAATAATATACTTGAA
TGCAATTTTGTAAAAGTGGATTCCTCAGGATATGTGAAACCTAAAGGAAGTGGTTCTGTTGCAAATGGACTATAAACAGGGACATTATAT
TCTTACACTAAAAATCCTTGCATTTTAAAGAGAGATGCACTTAAGAATAGAGTGAACTGCTCATATGCTTATTTAAGCTTGGACAGTTTT
CAGAGACAAACCCCATTAAGAATTACTCTTTTCACATGGCTGAATCGAAACATGTGTAATGTCAATGTAAAACCAATCACAGCTGTGAAC
TGCATGAAATGTATTGTGAAACGAACACAAGATTAAGCTTTGTCAGGTTAATGTAGCATGTTAAGGACTCTAGAAAAAAATAAACTAAGG

>In-frame_KDM4C_ENST00000381306_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_2691nt
CGGCGCCCAGGAGGACGTGTGGCGCGTGGACTACATCAGGTCCAGCCCTGCGGGACCCCAGCCAGCGCTTCCGGGCAAGGTTCTGTGCAC
CTGTTTTCTCCTTCTACGCGAGTATCTTTCCCCTCCGGAAAGAATGGGATATGCCTGTGTCCAAAGGACAAGAAGATGCGCGCCAGCAAG
CCTAAGTTAACCACAGCGCGGAAGTTGAGCCCAAAGCAAGAGCGTGCCGGGCACCTTTAAGCTGTTTGTAAGCCCACGTGACTCACCAAG
TGCGGGCCCCAGCGGTCACGTGACGGCGCGCGCGCCCTCGCGCAGGGAGAGCCGGCGGTGCGCGCGCCTTCGCCGCTGCCTCCCACCCAC
CCCCTCGACGGGAGGGTGAGGCGCGGCGCAGTGATCGGGCGGCCGGGGTCCTGTGCGCGTGCGCAGCGAACAGCTGTCACCTAGTGCGGA
ACAAGTCTCCCAAATTTCCCAAATCTCCCTGGGCCGGAGGCCACTGTCTTCTCTTCCTCCTCCACCGAGTCGTGCTCTCGCCCCAACCCG
CGCGCCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTC
CATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCC
TAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGG
ACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAG
ATACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCAT
ATATGATGAGATTTGACTGAAGAACGACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGG
AGTTCCCCAGATGTGGCAAAGAGTAAGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAG
AAAAACGGAGGCAACCCCGAGAGCCGCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACT
GTTTCTCTGCCCTTCAGCTTGAAAGCCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAG
CTCATCCTCAAGGGCTGTGGCGGGGACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACT
TCCGCAGAACCTGAGAGTCTAGCGTTGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGG
TCTGTGGGATCAGCCTTTCGAGTCCCAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTG
CAGCCCCCTTTCCCCCAGCCACCCCGGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGAT
GTCACCCTGTGGAACACCATGACGCTGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTC
TTCAGAAGCTCGCCCGTCCTTCCTGCCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAG
TCCATTTACACCGAGGACGACTATGACGAGAGGTCTGACTCCTCAGACTCTAGAACACTCAACACATCATCTTAAAGTGGTGCTGGATGG
GTGGTGGCCAGGTGACATTTTCTGTGCGTTTTGACCCTGAGGCATCTGAGGAGAGGCCACATCTTGTGTATGCCCTTTCCTTCTGTTTGA
CAAAGTGACTGTGCTTGATTCTATACATTAGCAATAAAAACATAACTTATTTAACTTCTTGCACTTCACTGGAAAATGCCAAATAGCTCT
GTTCTGTGGCTTTAGTGCTGAATGTTTATTGTAAAAGAGAGTCTAATGTTAAGAATAGTCTTGGGAAGGCTGGGTCCGTGGAAGATTTAT
TTGGGGATGTAAAGCTGAAGGTCAGCCTTGCACCTAAACCCAACCTGGAATGTTAAATGAAATAATATACTTGAATGCAATTTTGTAAAA
GTGGATTCCTCAGGATATGTGAAACCTAAAGGAAGTGGTTCTGTTGCAAATGGACTATAAACAGGGACATTATATTCTTACACTAAAAAT
CCTTGCATTTTAAAGAGAGATGCACTTAAGAATAGAGTGAACTGCTCATATGCTTATTTAAGCTTGGACAGTTTTCAGAGACAAACCCCA
TTAAGAATTACTCTTTTCACATGGCTGAATCGAAACATGTGTAATGTCAATGTAAAACCAATCACAGCTGTGAACTGCATGAAATGTATT

>In-frame_KDM4C_ENST00000381309_chr9_6814745_+_DMRT3_ENST00000190165_chr9_990041_+_2691nt
CGGCGCCCAGGAGGACGTGTGGCGCGTGGACTACATCAGGTCCAGCCCTGCGGGACCCCAGCCAGCGCTTCCGGGCAAGGTTCTGTGCAC
CTGTTTTCTCCTTCTACGCGAGTATCTTTCCCCTCCGGAAAGAATGGGATATGCCTGTGTCCAAAGGACAAGAAGATGCGCGCCAGCAAG
CCTAAGTTAACCACAGCGCGGAAGTTGAGCCCAAAGCAAGAGCGTGCCGGGCACCTTTAAGCTGTTTGTAAGCCCACGTGACTCACCAAG
TGCGGGCCCCAGCGGTCACGTGACGGCGCGCGCGCCCTCGCGCAGGGAGAGCCGGCGGTGCGCGCGCCTTCGCCGCTGCCTCCCACCCAC
CCCCTCGACGGGAGGGTGAGGCGCGGCGCAGTGATCGGGCGGCCGGGGTCCTGTGCGCGTGCGCAGCGAACAGCTGTCACCTAGTGCGGA
ACAAGTCTCCCAAATTTCCCAAATCTCCCTGGGCCGGAGGCCACTGTCTTCTCTTCCTCCTCCACCGAGTCGTGCTCTCGCCCCAACCCG
CGCGCCAGACACTGCCCTAACCATCATGGAGGTGGCCGAGGTGGAAAGTCCTCTGAACCCCAGCTGTAAGATAATGACCTTCAGACCCTC
CATGGAGGAGTTCCGGGAGTTCAACAAATACCTTGCATACATGGAGTCTAAAGGAGCCCATCGTGCGGGTCTTGCAAAGGTGATTCCTCC
TAAGGAGTGGAAGCCAAGACAGTGCTATGATGACATTGATAATTTGCTCATTCCAGCACCAATTCAGCAGATGGTCACAGGGCAGTCAGG
ACTGTTCACTCAGTACAACATCCAGAAAAAAGCGATGACTGTGAAGGAGTTCAGGCAGCTGGCCAACAGTGGCAAATATTGTACTCCAAG
ATACTTGGATTACGAAGATTTGGAGCGCAAGTACTGGAAGAACTTAACTTTTGTGGCACCTATCTATGGTGCAGATATTAATGGGAGCAT
ATATGATGAGATTTGACTGAAGAACGACTTGGAGACGGCAAGTCGGCAGACAATACAGAGGTCTTCAGTGACAAAGACACTGACCAGAGG
AGTTCCCCAGATGTGGCAAAGAGTAAGGGCTGCTTCACCCCTGAGAGCCCTGAGATAGTGTCCGTGGAGGAAGGGGGATACGCTGTCCAG
AAAAACGGAGGCAACCCCGAGAGCCGCCCTGACAGCCCCAAGTGTCACGCGGAGCAGAATCACCTCCTGATTGAGGGCCCCTCGGGGACT
GTTTCTCTGCCCTTCAGCTTGAAAGCCAACAGACCGCCGCTTGAAGTGTTAAAAAAGATATTCCCCAACCAGAAGCCAACGGTGCTTGAG
CTCATCCTCAAGGGCTGTGGCGGGGACCTGGTGAGCGCCGTGGAAGTCCTTCTGTCCAGCCGATCCTCAGTCACGGGAGCAGAGCGAACT
TCCGCAGAACCTGAGAGTCTAGCGTTGCCCTCCAATGGGCACATCTTTGAACACACCTTGAGCTCCTACCCCATCTCGTCTTCCAAATGG
TCTGTGGGATCAGCCTTTCGAGTCCCAGACACGTTGAGGTTTTCTGCCGACTCTAGCAACGTTGTCCCCAGTCCCTTGGCTGGGCCTCTG
CAGCCCCCTTTCCCCCAGCCACCCCGGTACCCGCTGATGCTGAGGAATACTTTGGCGAGAAGCCAGTCGAGCCCCTTTTTGCCCAATGAT
GTCACCCTGTGGAACACCATGACGCTGCAGCAGCAGTATCAGCTGAGGTCCCAGTATGTCAGTCCTTTCCCCAGTAACTCTACCAGCGTC
TTCAGAAGCTCGCCCGTCCTTCCTGCCCGCGCCACGGAAGACCCTCGGATTTCCATCCCTGATGATGGGTGTCCATTTGTGTCAAAGCAG
TCCATTTACACCGAGGACGACTATGACGAGAGGTCTGACTCCTCAGACTCTAGAACACTCAACACATCATCTTAAAGTGGTGCTGGATGG
GTGGTGGCCAGGTGACATTTTCTGTGCGTTTTGACCCTGAGGCATCTGAGGAGAGGCCACATCTTGTGTATGCCCTTTCCTTCTGTTTGA
CAAAGTGACTGTGCTTGATTCTATACATTAGCAATAAAAACATAACTTATTTAACTTCTTGCACTTCACTGGAAAATGCCAAATAGCTCT
GTTCTGTGGCTTTAGTGCTGAATGTTTATTGTAAAAGAGAGTCTAATGTTAAGAATAGTCTTGGGAAGGCTGGGTCCGTGGAAGATTTAT
TTGGGGATGTAAAGCTGAAGGTCAGCCTTGCACCTAAACCCAACCTGGAATGTTAAATGAAATAATATACTTGAATGCAATTTTGTAAAA
GTGGATTCCTCAGGATATGTGAAACCTAAAGGAAGTGGTTCTGTTGCAAATGGACTATAAACAGGGACATTATATTCTTACACTAAAAAT
CCTTGCATTTTAAAGAGAGATGCACTTAAGAATAGAGTGAACTGCTCATATGCTTATTTAAGCTTGGACAGTTTTCAGAGACAAACCCCA
TTAAGAATTACTCTTTTCACATGGCTGAATCGAAACATGTGTAATGTCAATGTAAAACCAATCACAGCTGTGAACTGCATGAAATGTATT


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FusionGenePPI for KDM4C_DMRT3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
KDM4CKDM4A, KDM4C, HIST1H3A, H3F3A, PPARG, HDAC1, HDAC3, HIST2H3C, SHMT2, MOV10, NXF1, TRIM25DMRT3TRIM23, KRTAP5-9, KRT31, MDFI, PLSCR1, PSMA3, REL, TRIM27, SAT1, TCF4, TRAF1, TRIP6, KHDRBS3, RBPMS, MID2, MTUS2, CCNDBP1, UBASH3B, KRT40, MGAT5B, KRTAP10-7, KRTAP10-9, KRTAP10-8, KRTAP10-3, INCA1, NOTCH2NL


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for KDM4C_DMRT3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for KDM4C_DMRT3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKDM4CC0025149Medulloblastoma1CTD_human
HgeneKDM4CC0236663Alcohol withdrawal syndrome1PSYGENET