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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 18299

FusionGeneSummary for KCNMA1_MSMB

check button Fusion gene summary
Fusion gene informationFusion gene name: KCNMA1_MSMB
Fusion gene ID: 18299
HgeneTgene
Gene symbol

KCNMA1

MSMB

Gene ID

3778

4477

Gene namepotassium calcium-activated channel subfamily M alpha 1microseminoprotein beta
SynonymsBKTM|CADEDS|KCa1.1|MaxiK|PNKD3|SAKCA|SLO|SLO-ALPHA|SLO1|bA205K10.1|hSlo|mSLO1HPC13|IGBF|MSP|MSPB|PN44|PRPS|PSP|PSP-94|PSP57|PSP94
Cytomap

10q22.3

10q11.22

Type of geneprotein-codingprotein-coding
Descriptioncalcium-activated potassium channel subunit alpha-1uncharacterized proteinBK channel alpha subunitBKCA alpha subunitbig potassium channel alpha subunitcalcium-activated potassium channel, subfamily M subunit alpha-1k(VCA)alphamaxi-K channel HSLOpobeta-microseminoproteinimmunoglobulin binding factorprostate secreted seminal plasma proteinprostate secretory protein of 94 amino acidsseminal plasma beta-inhibin
Modification date2018052320180519
UniProtAcc

Q12791

P08118

Ensembl transtripts involved in fusion geneENST00000404771, ENST00000372440, 
ENST00000372443, ENST00000286628, 
ENST00000286627, ENST00000354353, 
ENST00000404857, ENST00000406533, 
ENST00000484507, ENST00000481070, 
ENST00000480683, 		ENST00000358559, 
ENST00000474170, ENST00000298239, 
Fusion gene scores* DoF score15 X 12 X 8=14403 X 1 X 5=15
# samples 175
** MAII scorelog2(17/1440*10)=-3.08246216019197
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/15*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: KCNMA1 [Title/Abstract] AND MSMB [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKCNMA1

GO:0001666

response to hypoxia

15528406

HgeneKCNMA1

GO:0006813

potassium ion transport

7573516|7877450|11245614|12388065|17706472|18458941

HgeneKCNMA1

GO:0006970

response to osmotic stress

10840032|12388065

HgeneKCNMA1

GO:0030007

cellular potassium ion homeostasis

11245614

HgeneKCNMA1

GO:0034465

response to carbon monoxide

15528406

HgeneKCNMA1

GO:0042391

regulation of membrane potential

7877450|7993625

HgeneKCNMA1

GO:0045794

negative regulation of cell volume

12388065

HgeneKCNMA1

GO:0051592

response to calcium ion

12388065|18458941

HgeneKCNMA1

GO:0060073

micturition

11641143

HgeneKCNMA1

GO:0060083

smooth muscle contraction involved in micturition

11641143


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-A2-A25D-01AKCNMA1chr10

78869931

-MSMBchr10

51555731

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000404771ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000404771ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000404771ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000372440ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000372440ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000372440ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000372443ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000372443ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000372443ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000286628ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000286628ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000286628ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000286627ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000286627ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000286627ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000354353ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000354353ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000354353ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000404857ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000404857ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000404857ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
In-frameENST00000406533ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000406533ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
5CDS-3UTRENST00000406533ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3CDSENST00000484507ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000484507ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000484507ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3CDSENST00000481070ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000481070ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000481070ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3CDSENST00000480683ENST00000358559KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000480683ENST00000474170KCNMA1chr10

78869931

-MSMBchr10

51555731

+
intron-3UTRENST00000480683ENST00000298239KCNMA1chr10

78869931

-MSMBchr10

51555731

+

Top

FusionProtFeatures for KCNMA1_MSMB


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KCNMA1

Q12791

MSMB

P08118


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-82713_203771179Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-82739_603771179Compositional biasNote=Poly-Ser
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-8274_103771179Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-82813_203771237Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-82839_603771237Compositional biasNote=Poly-Ser
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-8284_103771237Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-82813_203771220Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-82839_603771220Compositional biasNote=Poly-Ser
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-8284_103771220Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827336_3583771179IntramembranePore-forming%3B Name%3DP region
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828336_3583771237IntramembranePore-forming%3B Name%3DP region
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828336_3583771220IntramembranePore-forming%3B Name%3DP region
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827352_3553771179MotifNote=Selectivity for potassium
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828352_3553771237MotifNote=Selectivity for potassium
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828352_3553771220MotifNote=Selectivity for potassium
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827108_1783771179Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-8271_863771179Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827200_2143771179Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827236_2393771179Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827261_2643771179Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827286_3003771179Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827322_3353771179Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827359_3673771179Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828108_1783771237Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-8281_863771237Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828200_2143771237Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828236_2393771237Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828261_2643771237Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828286_3003771237Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828322_3353771237Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828359_3673771237Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828108_1783771220Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-8281_863771220Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828200_2143771220Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828236_2393771220Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828261_2643771220Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828286_3003771220Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828322_3353771220Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828359_3673771220Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827179_1993771179TransmembraneHelical%3B Name%3DSegment S1
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827215_2353771179TransmembraneHelical%3B Name%3DSegment S2
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827240_2603771179TransmembraneHelical%3B Name%3DSegment S3
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827265_2853771179TransmembraneHelical%3B Name%3DSegment S4
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827301_3213771179TransmembraneHelical%3B Name%3DSegment S5
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-82787_1073771179TransmembraneHelical%3B Name%3DSegment S0
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828179_1993771237TransmembraneHelical%3B Name%3DSegment S1
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828215_2353771237TransmembraneHelical%3B Name%3DSegment S2
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828240_2603771237TransmembraneHelical%3B Name%3DSegment S3
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828265_2853771237TransmembraneHelical%3B Name%3DSegment S4
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828301_3213771237TransmembraneHelical%3B Name%3DSegment S5
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-82887_1073771237TransmembraneHelical%3B Name%3DSegment S0
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828179_1993771220TransmembraneHelical%3B Name%3DSegment S1
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828215_2353771220TransmembraneHelical%3B Name%3DSegment S2
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828240_2603771220TransmembraneHelical%3B Name%3DSegment S3
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828265_2853771220TransmembraneHelical%3B Name%3DSegment S4
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828301_3213771220TransmembraneHelical%3B Name%3DSegment S5
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-82887_1073771220TransmembraneHelical%3B Name%3DSegment S0

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-1213_20-117169Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-1239_60-117169Compositional biasNote=Poly-Ser
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-124_10-117169Compositional biasNote=Poly-Gly
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827415_5583771179DomainNote=RCK N-terminal
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828415_5583771237DomainNote=RCK N-terminal
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828415_5583771220DomainNote=RCK N-terminal
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12415_558-117169DomainNote=RCK N-terminal
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12336_358-117169IntramembranePore-forming%3B Name%3DP region
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-8271003_10253771179MotifNote=Calcium bowl
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-8281003_10253771237MotifNote=Calcium bowl
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-8281003_10253771220MotifNote=Calcium bowl
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-121003_1025-117169MotifNote=Calcium bowl
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12352_355-117169MotifNote=Selectivity for potassium
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-8271032_10523771179RegionNote=Segment S10
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827556_5763771179RegionNote=Segment S7
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827613_6333771179RegionNote=Segment S8
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827677_6813771179RegionNote=Heme-binding motif
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827837_8573771179RegionNote=Segment S9
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-8281032_10523771237RegionNote=Segment S10
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828556_5763771237RegionNote=Segment S7
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828613_6333771237RegionNote=Segment S8
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828677_6813771237RegionNote=Heme-binding motif
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828837_8573771237RegionNote=Segment S9
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-8281032_10523771220RegionNote=Segment S10
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828556_5763771220RegionNote=Segment S7
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828613_6333771220RegionNote=Segment S8
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828677_6813771220RegionNote=Heme-binding motif
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828837_8573771220RegionNote=Segment S9
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-121032_1052-117169RegionNote=Segment S10
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12556_576-117169RegionNote=Segment S7
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12613_633-117169RegionNote=Segment S8
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12677_681-117169RegionNote=Heme-binding motif
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12837_857-117169RegionNote=Segment S9
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827389_12363771179Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828389_12363771237Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828389_12363771220Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12108_178-117169Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-121_86-117169Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12200_214-117169Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12236_239-117169Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12261_264-117169Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12286_300-117169Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12322_335-117169Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12359_367-117169Topological domainExtracellular
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12389_1236-117169Topological domainCytoplasmic
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286627-827368_3883771179TransmembraneHelical%3B Name%3DSegment S6
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000286628-828368_3883771237TransmembraneHelical%3B Name%3DSegment S6
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000404857-828368_3883771220TransmembraneHelical%3B Name%3DSegment S6
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12179_199-117169TransmembraneHelical%3B Name%3DSegment S1
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12215_235-117169TransmembraneHelical%3B Name%3DSegment S2
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12240_260-117169TransmembraneHelical%3B Name%3DSegment S3
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12265_285-117169TransmembraneHelical%3B Name%3DSegment S4
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12301_321-117169TransmembraneHelical%3B Name%3DSegment S5
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-12368_388-117169TransmembraneHelical%3B Name%3DSegment S6
HgeneKCNMA1chr10:78869931chr10:51555731ENST00000480683-1287_107-117169TransmembraneHelical%3B Name%3DSegment S0


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FusionGeneSequence for KCNMA1_MSMB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_KCNMA1_ENST00000404771_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000372440_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000372443_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000286628_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000286627_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000354353_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000404857_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS

>In-frame_KCNMA1_ENST00000406533_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_491aa
MANGGGGGGGSSGGGGGGGGSSLRMSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAF
LASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVL
VVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLG
LRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYA
KTTLGRLFMVFFILGGLNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETCTCYETEISCCTLVS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_KCNMA1_ENST00000404771_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000372440_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000372443_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000286628_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000286627_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000354353_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000404857_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA

>In-frame_KCNMA1_ENST00000406533_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1473nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_KCNMA1_ENST00000404771_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1706nt
GGCGGCGGCGGCGGCGGCAGCAGTAGCAGCAATATGGCTGTTGATGGGTGTTTGGGGTGGCGCTGGCGGCGGGAGGAGCTCCCCCGAGCC
CCTGCGCCGGCTGCCCGTTGCTAGCTATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCA
GTCTTAGAATGAGTAGCAATATCCACGCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTT
CCTCCTCCTCTTCCTCCTCGTCCTCGGTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCC
GGGGCCAACGCATGTGGTGGGCTTTCCTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCA
AGTACCTGTGGACCGTGTGCTGCCACTGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTC
TCAAACCAGTGGATGAAAAAGAGGAGGCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCG
CCCAGACACTGACTGGCAGAGTCCTGGTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACC
CAATAGAATCCTGCCAGAATTTCTACAAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGC
GGTTTATTGCAGCCAACGATAAATTGTGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTG
TGTACTTAAACAGAAGTTGGCTTGGTTTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTC
TTAAAACAAGTAATTCCATCAAGCTGGTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGG
AGAATTCAGGGGACCCATGGGAAAATTTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCA
CCGTTGGTTATGGGGATGTTTATGCAAAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGG
GCAGCGTTGTGATCTTTGCCACCTTCGTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCA
GGAAATGCATGGATCTCAAAGGAAACAAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAG
AAATTTCATGTTGCACCCTTGTTTCTACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATA
TCGTGGTGGAGAAGAAGGACCCAAAAAAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGC

>In-frame_KCNMA1_ENST00000372440_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1941nt
GGCGCAGACCCCGGGCGCGGGCGGCCCGCGGCGCCCCCTGGCTCTCGGCGCTCGGGGCCAGCGCAGCCCGGGGCGAGCGGGGCGCGGGCC
GGGGAGGGGGAGCTGCCCGCGCACTCCATCCCCCTCCCCCCCGGGCGGGCGGCGGCGGCTCGCTGTATATATCTCGGCGCACCCCGCCAG
GTCGCGCACAGCGCCCCGAGCCCAGGCGCCTCCCCGCCCCCCTCCCGCGCTCCGCGGCGGCGGCGGCGGCGGCAGCAGTAGCAGCAATAT
GGCTGTTGATGGGTGTTTGGGGTGGCGCTGGCGGCGGGAGGAGCTCCCCCGAGCCCCTGCGCCGGCTGCCCGTTGCTAGCTATGGCAAAT
GGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCACGCGAACCAT
CTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCGGTCCACGAG
CCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTCCTGGCCTCC
TCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCACTGCGGGGGC
AAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAGGCAGTGGCC
GCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTGGTTGTCTTA
GTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTACAAAGATTTC
ACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTGTGGTTCTGG
CTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGTTTGAGATTT
TTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTGGTGAATCTG
CTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAATTTCCAAAAC
AACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCAAAAACCACA
CTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTCGTGACTTTA
TGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAACAAACACCCA
ATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCTACACCTGTG
GGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAAAAGACCTGT
TCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTAATAGTCAAT

>In-frame_KCNMA1_ENST00000372443_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_2317nt
GCGAGCGGAGGCCGAGGGGCTCAGCGGCGTGGCGACAGGACTAGGGGGTCCCGAGAACATGGGCTAGCAGGCGGCCACGGGCCGGCGGCC
GGACGCGGTGAACCTGCCGCGGCCGGGCGCGCACTGGCGCGGCGAGCCGGAGCCGAGCGCAGCCGGGGGAGGAGGGCTGGCGCAGGGGCG
CCCGGGCGGAGGGGGCCGATTATCCATTATTAACGAGTTACCACCTAATAAGCGGAGAGCGGCTCGTTAGCCGCGCGGGAGGCGCTCGGG
GAAGGGGGTCACCGGCCGAGCGCAGCGCACACCCGTGGCGCACGGCGGGCGGCGCGGCGCCGAGGACACCCGGGACCGCGCGCGGAGCCG
GGGCGGGCCCGGGGGCGGCGCAGACCCCGGGCGCGGGCGGCCCGCGGCGCCCCCTGGCTCTCGGCGCTCGGGGCCAGCGCAGCCCGGGGC
GAGCGGGGCGCGGGCCGGGGAGGGGGAGCTGCCCGCGCACTCCATCCCCCTCCCCCCCGGGCGGGCGGCGGCGGCTCGCTGTATATATCT
CGGCGCACCCCGCCAGGTCGCGCACAGCGCCCCGAGCCCAGGCGCCTCCCCGCCCCCCTCCCGCGCTCCGCGGCGGCGGCGGCGGCGGCA
GCAGTAGCAGCAATATGGCTGTTGATGGGTGTTTGGGGTGGCGCTGGCGGCGGGAGGAGCTCCCCCGAGCCCCTGCGCCGGCTGCCCGTT
GCTAGCTATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAA
TATCCACGCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTC
GTCCTCGGTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTG
GGCTTTCCTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTG
CTGCCACTGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAA
AGAGGAGGCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAG
AGTCCTGGTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAA
TTTCTACAAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGA
TAAATTGTGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTG
GCTTGGTTTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCAT
CAAGCTGGTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATG
GGAAAATTTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGT
TTATGCAAAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGC
CACCTTCGTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAA
AGGAAACAAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCT
TGTTTCTACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGA
CCCAAAAAAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTG

>In-frame_KCNMA1_ENST00000286628_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1590nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA
AAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTA

>In-frame_KCNMA1_ENST00000286627_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_2543nt
CCGGGCCGCTGCCGAGGGGCCCTGCCCACCCCTGCCCAGCCCGGAGCCCAGGCGAGCCAGCGCGGCGAGCCTCCTCCCCTCCCGCCTGGG
TCGTCCTGAGTCCGCGCCCGCTCCAGTTGCTGCAGCTGCTGCTGCTGGCGGCTGCGGGGAGCGCGGGGCGCGCGCCGAAGAGGCTTGGGC
GGCGAGGACGGGGACGAGGAGGAGTCGGAGGCGGCAAGGAGGAAGAGCGAGCGGAGGCCGAGGGGCTCAGCGGCGTGGCGACAGGACTAG
GGGGTCCCGAGAACATGGGCTAGCAGGCGGCCACGGGCCGGCGGCCGGACGCGGTGAACCTGCCGCGGCCGGGCGCGCACTGGCGCGGCG
AGCCGGAGCCGAGCGCAGCCGGGGGAGGAGGGCTGGCGCAGGGGCGCCCGGGCGGAGGGGGCCGATTATCCATTATTAACGAGTTACCAC
CTAATAAGCGGAGAGCGGCTCGTTAGCCGCGCGGGAGGCGCTCGGGGAAGGGGGTCACCGGCCGAGCGCAGCGCACACCCGTGGCGCACG
GCGGGCGGCGCGGCGCCGAGGACACCCGGGACCGCGCGCGGAGCCGGGGCGGGCCCGGGGGCGGCGCAGACCCCGGGCGCGGGCGGCCCG
CGGCGCCCCCTGGCTCTCGGCGCTCGGGGCCAGCGCAGCCCGGGGCGAGCGGGGCGCGGGCCGGGGAGGGGGAGCTGCCCGCGCACTCCA
TCCCCCTCCCCCCCGGGCGGGCGGCGGCGGCTCGCTGTATATATCTCGGCGCACCCCGCCAGGTCGCGCACAGCGCCCCGAGCCCAGGCG
CCTCCCCGCCCCCCTCCCGCGCTCCGCGGCGGCGGCGGCGGCGGCAGCAGTAGCAGCAATATGGCTGTTGATGGGTGTTTGGGGTGGCGC
TGGCGGCGGGAGGAGCTCCCCCGAGCCCCTGCGCCGGCTGCCCGTTGCTAGCTATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCG
GCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCACGCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCT
CCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCGGTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGG
TGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTCCTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCT
TCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCACTGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACA
ATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAGGCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGA
AGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTGGTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTG
TAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTACAAAGATTTCACATTACAGATCGACATGGCTTTCAACG
TGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTGTGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCT
TCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGTTTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTT
CAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTGGTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGA
CTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAATTTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTG
TCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCAAAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCA
TCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTCGTGACTTTATGCAATGCATCATGCTATTTCATACCTA
ATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAACAAACACCCAATAAACTCGGAGTGGCAGACTGACAACT
GTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCTACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAA
TCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAAAAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTG
CTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTAATAGTCAATGATTGTGTAGCCATGCCTATCAGTAAAA

>In-frame_KCNMA1_ENST00000354353_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1590nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA
AAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTA

>In-frame_KCNMA1_ENST00000404857_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1590nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA
AAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTA

>In-frame_KCNMA1_ENST00000406533_chr10_78869931_-_MSMB_ENST00000358559_chr10_51555731_+_1590nt
ATGGCAAATGGTGGCGGCGGCGGCGGCGGCAGCAGCGGCGGCGGCGGCGGCGGCGGAGGCAGCAGTCTTAGAATGAGTAGCAATATCCAC
GCGAACCATCTCAGCCTAGACGCGTCCTCCTCCTCCTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCCTCTTCCTCCTCGTCCTCG
GTCCACGAGCCCAAGATGGATGCGCTCATCATCCCGGTGACCATGGAGGTGCCGTGCGACAGCCGGGGCCAACGCATGTGGTGGGCTTTC
CTGGCCTCCTCCATGGTGACTTTCTTCGGGGGCCTCTTCATCATCTTGCTCTGGCGGACGCTCAAGTACCTGTGGACCGTGTGCTGCCAC
TGCGGGGGCAAGACGAAGGAGGCCCAGAAGATTAACAATGGCTCAAGCCAGGCGGATGGCACTCTCAAACCAGTGGATGAAAAAGAGGAG
GCAGTGGCCGCCGAGGTCGGCTGGATGACCTCCGTGAAGGACTGGGCGGGGGTGATGATATCCGCCCAGACACTGACTGGCAGAGTCCTG
GTTGTCTTAGTCTTTGCTCTCAGCATCGGTGCACTTGTAATATACTTCATAGATTCATCAAACCCAATAGAATCCTGCCAGAATTTCTAC
AAAGATTTCACATTACAGATCGACATGGCTTTCAACGTGTTCTTCCTTCTCTACTTCGGCTTGCGGTTTATTGCAGCCAACGATAAATTG
TGGTTCTGGCTGGAAGTGAACTCTGTAGTGGATTTCTTCACGGTGCCCCCCGTGTTTGTGTCTGTGTACTTAAACAGAAGTTGGCTTGGT
TTGAGATTTTTAAGAGCTCTGAGACTGATACAGTTTTCAGAAATTTTGCAGTTTCTGAATATTCTTAAAACAAGTAATTCCATCAAGCTG
GTGAATCTGCTCTCCATATTTATCAGCACGTGGCTGACTGCAGCCGGGTTCATCCATTTGGTGGAGAATTCAGGGGACCCATGGGAAAAT
TTCCAAAACAACCAGGCTCTCACCTACTGGGAATGTGTCTATTTACTCATGGTCACAATGTCCACCGTTGGTTATGGGGATGTTTATGCA
AAAACCACACTTGGGCGCCTCTTCATGGTCTTCTTCATCCTCGGGGGACTGAATGTTCTCCTGGGCAGCGTTGTGATCTTTGCCACCTTC
GTGACTTTATGCAATGCATCATGCTATTTCATACCTAATGAGGGAGTTCCAGGAGATTCAACCAGGAAATGCATGGATCTCAAAGGAAAC
AAACACCCAATAAACTCGGAGTGGCAGACTGACAACTGTGAGACATGCACTTGCTACGAAACAGAAATTTCATGTTGCACCCTTGTTTCT
ACACCTGTGGGTTATGACAAAGACAACTGCCAAAGAATCTTCAAGAAGGAGGACTGCAAGTATATCGTGGTGGAGAAGAAGGACCCAAAA
AAGACCTGTTCTGTCAGTGAATGGATAATCTAATGTGCTTCTAGTAGGCACAGGGCTCCCAGGCCAGGCCTCATTCTCCTCTGGCCTCTA


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FusionGenePPI for KCNMA1_MSMB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
KCNMA1ALB, CAV1, CAV2, CAV3, ACTA2, ACTG2, TBXA2R, KCNMA1, KCNMB1, EED, PTPRAMSMBAPP, SGTA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for KCNMA1_MSMB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneKCNMA1Q12791DB00356ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1small moleculeapproved
HgeneKCNMA1Q12791DB00436BendroflumethiazideCalcium-activated potassium channel subunit alpha-1small moleculeapproved
HgeneKCNMA1Q12791DB01003Cromoglicic acidCalcium-activated potassium channel subunit alpha-1small moleculeapproved
HgeneKCNMA1Q12791DB01119DiazoxideCalcium-activated potassium channel subunit alpha-1small moleculeapproved
HgeneKCNMA1Q12791DB09089TrimebutineCalcium-activated potassium channel subunit alpha-1small moleculeapproved
HgeneKCNMA1Q12791DB00774HydroflumethiazideCalcium-activated potassium channel subunit alpha-1small moleculeapproved|investigational
HgeneKCNMA1Q12791DB04209DequaliniumCalcium-activated potassium channel subunit alpha-1small moleculeapproved|investigational
HgeneKCNMA1Q12791DB00721ProcaineCalcium-activated potassium channel subunit alpha-1small moleculeapproved|investigational|vet_approved
HgeneKCNMA1Q12791DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1small moleculeapproved|investigational|vet_approved
HgeneKCNMA1Q12791DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1small moleculeapproved|vet_approved
HgeneKCNMA1Q12791DB01159HalothaneCalcium-activated potassium channel subunit alpha-1small moleculeapproved|vet_approved

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RelatedDiseases for KCNMA1_MSMB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKCNMA1C0004352Autistic Disorder1CTD_human
HgeneKCNMA1C0005944Metabolic Bone Disorder1CTD_human
HgeneKCNMA1C0007134Renal Cell Carcinoma1CTD_human
HgeneKCNMA1C0019284Diaphragmatic Hernia1CTD_human
HgeneKCNMA1C0028756Obesity, Morbid1CTD_human
HgeneKCNMA1C0038220Status Epilepticus1CTD_human
HgeneKCNMA1C1836173Generalized Epilepsy and Paroxysmal Dyskinesia1CTD_human;ORPHANET;UNIPROT
TgeneMSMBC0033578Prostatic Neoplasms3CTD_human