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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 17974

FusionGeneSummary for ITSN1_MAP3K7CL

check button Fusion gene summary
Fusion gene informationFusion gene name: ITSN1_MAP3K7CL
Fusion gene ID: 17974
HgeneTgene
Gene symbol

ITSN1

MAP3K7CL

Gene ID

6453

56911

Gene nameintersectin 1MAP3K7 C-terminal like
SynonymsITSN|SH3D1A|SH3P17C21orf7|HC21ORF7|TAK1L|TAKL|TAKL-1|TAKL-2|TAKL-4
Cytomap

21q22.11

21q21.3

Type of geneprotein-codingprotein-coding
Descriptionintersectin-1SH3 domain-containing protein 1ASrc homology 3 domain-containing proteinhuman intersectin-SH3 domain-containing protein SH3P17intersectin 1 (SH3 domain protein)intersectin 1 short form variant 3intersectin 1 short form variant, 11interMAP3K7 C-terminal-like proteinTAK1-like protein 1TAK1-like protein 2TAK1-like protein 4TGF-beta activated kinase
Modification date2018052220180519
UniProtAcc

Q15811

P57077

Ensembl transtripts involved in fusion geneENST00000399353, ENST00000381318, 
ENST00000381291, ENST00000381285, 
ENST00000399367, ENST00000399352, 
ENST00000399355, ENST00000399349, 
ENST00000399338, ENST00000379960, 
ENST00000437442, ENST00000399326, 
ENST00000488166, 		ENST00000545939, 
ENST00000286791, ENST00000399934, 
ENST00000341618, ENST00000399935, 
ENST00000399947, ENST00000339024, 
ENST00000399928, ENST00000399926, 
ENST00000399925, ENST00000496779, 
Fusion gene scores* DoF score8 X 3 X 7=1682 X 2 X 2=8
# samples 82
** MAII scorelog2(8/168*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: ITSN1 [Title/Abstract] AND MAP3K7CL [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDTHYMTCGA-ZB-A969-01AITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000399353ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399353ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000399353ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000381318ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381318ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000381318ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000381291ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381291ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000381291ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000381285ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000381285ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000381285ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000399367ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399367ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000399367ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000399352ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399352ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000399352ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000399355ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399355ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000399355ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3CDSENST00000399349ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-3UTRENST00000399349ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
5UTR-intronENST00000399349ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3CDSENST00000399338ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399338ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-intronENST00000399338ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3CDSENST00000379960ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000379960ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-intronENST00000379960ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3CDSENST00000437442ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000437442ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-intronENST00000437442ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3CDSENST00000399326ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000399326ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-intronENST00000399326ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3CDSENST00000488166ENST00000545939ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000286791ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399934ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000341618ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399935ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399947ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000339024ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399928ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399926ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-3UTRENST00000488166ENST00000399925ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+
intron-intronENST00000488166ENST00000496779ITSN1chr21

35015019

+MAP3K7CLchr21

30532262

+

Top

FusionProtFeatures for ITSN1_MAP3K7CL


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITSN1

Q15811

MAP3K7CL

P57077


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for ITSN1_MAP3K7CL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for ITSN1_MAP3K7CL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ITSN1SCAMP1, TSG101, DISC1, SMARCC2, MRPL20, SNX5, EEF1A1, KIF5A, UNC119, STON2, SNAP25, SNAP23, EPHB2, SOS1, CDC42, WASL, CBL, DNM2, MAPK8IP2, SH3GL2, CSNK2B, RPS6KA5, TK1, UBE2K, MAPK6, PLK1, ZAK, AP2B1, ASAP2, PIK3AP1, PFDN5, SF3B4, CCNO, WBP11, EPN2, PICALM, FNBP4, ZFPM2, AGFG1, RAB11FIP2, DAB2, AGFG2, CLIP2, EPS15L1, GOLGA5, ITSN1, PPL, PIK3R1, PPFIA2, CYTH1, RNF40, SPDL1, CLTC, EPS15, KIF16B, ARFIP2, DES, FNBP1, GCC1, HIP1, MTUS2, CEP85L, PACSIN3, PDCD6IP, PREX1, RABEP1, RAI14, SCOC, TRIM8, PIK3C2B, GAREML, SPRY2, DLGAP1, SYNJ2, FCHSD2, ITSN2, RAB5A, ARF6, PDE4D, KHDRBS1, SH3KBP1, AMPH, SGIP1, REPS1, DNM1, ARHGAP31, SYNJ1, WAS, CBLB, PAK3, TTC37, SKIV2L, SETD3, IGBP1, RNASEH2A, DSTN, LMO4, PHGDH, NECAP2, DTX3, AP2M1, TFG, RAD18, ITCH, AP2S1, NCKIPSD, RUNDC3A, LSR, PDDC1, ALOX5, TRIM25MAP3K7CLTAB3, GPS2, CISH, KRT31, REL, AK8


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ITSN1_MAP3K7CL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ITSN1_MAP3K7CL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource